

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of osteoblast proliferation (GO:0033690) | 9.50703977 |
| 2 | cellular response to thyroid hormone stimulus (GO:0097067) | 8.55485667 |
| 3 | granulocyte differentiation (GO:0030851) | 7.03080392 |
| 4 | negative regulation of bone mineralization (GO:0030502) | 6.31218494 |
| 5 | erythrocyte development (GO:0048821) | 6.29709385 |
| 6 | response to thyroid hormone (GO:0097066) | 5.93107794 |
| 7 | positive regulation by symbiont of host defense response (GO:0052509) | 5.54573373 |
| 8 | modulation by symbiont of host defense response (GO:0052031) | 5.54573373 |
| 9 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.54573373 |
| 10 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.54573373 |
| 11 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.54573373 |
| 12 | modulation by symbiont of host immune response (GO:0052553) | 5.54573373 |
| 13 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 5.52135747 |
| 14 | negative regulation of biomineral tissue development (GO:0070168) | 5.48417668 |
| 15 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 5.40879622 |
| 16 | microglial cell activation (GO:0001774) | 5.18863728 |
| 17 | positive regulation of insulin receptor signaling pathway (GO:0046628) | 5.17633537 |
| 18 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 5.16955459 |
| 19 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 5.16955459 |
| 20 | positive regulation of erythrocyte differentiation (GO:0045648) | 5.12639074 |
| 21 | platelet formation (GO:0030220) | 5.08065976 |
| 22 | detection of molecule of bacterial origin (GO:0032490) | 4.87339248 |
| 23 | negative regulation of mast cell activation (GO:0033004) | 4.77898282 |
| 24 | embryonic hemopoiesis (GO:0035162) | 4.70771955 |
| 25 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.59116686 |
| 26 | nuclear envelope reassembly (GO:0031468) | 4.41742743 |
| 27 | mitotic nuclear envelope reassembly (GO:0007084) | 4.41742743 |
| 28 | natural killer cell activation involved in immune response (GO:0002323) | 4.39073282 |
| 29 | positive regulation of interferon-alpha production (GO:0032727) | 4.29197635 |
| 30 | purine ribonucleotide transport (GO:0015868) | 4.28055935 |
| 31 | mitochondrial calcium ion transport (GO:0006851) | 4.27621907 |
| 32 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.26556102 |
| 33 | macrophage activation involved in immune response (GO:0002281) | 4.22866478 |
| 34 | adenine nucleotide transport (GO:0051503) | 4.06735295 |
| 35 | positive regulation of cell cycle checkpoint (GO:1901978) | 4.05132524 |
| 36 | neutrophil mediated immunity (GO:0002446) | 4.04454597 |
| 37 | regulation of interferon-alpha production (GO:0032647) | 3.99261277 |
| 38 | negative regulation of gluconeogenesis (GO:0045721) | 3.99005296 |
| 39 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.85167139 |
| 40 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.76743427 |
| 41 | macrophage activation (GO:0042116) | 3.62773649 |
| 42 | regulation of erythrocyte differentiation (GO:0045646) | 3.58853610 |
| 43 | cell wall macromolecule catabolic process (GO:0016998) | 3.57909576 |
| 44 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 3.56247275 |
| 45 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.54905310 |
| 46 | regulation of pigment cell differentiation (GO:0050932) | 3.54459773 |
| 47 | myeloid cell development (GO:0061515) | 3.52888943 |
| 48 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.50568944 |
| 49 | response to host immune response (GO:0052572) | 3.50568944 |
| 50 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.50519233 |
| 51 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.49315942 |
| 52 | female mating behavior (GO:0060180) | 3.45864121 |
| 53 | positive regulation of cellular response to insulin stimulus (GO:1900078) | 3.45473423 |
| 54 | myeloid leukocyte mediated immunity (GO:0002444) | 3.40219486 |
| 55 | regulation of osteoblast proliferation (GO:0033688) | 3.36191707 |
| 56 | mannose metabolic process (GO:0006013) | 3.33003353 |
| 57 | outer ear morphogenesis (GO:0042473) | 3.32955200 |
| 58 | mitochondrial calcium ion homeostasis (GO:0051560) | 3.30880857 |
| 59 | protein targeting to vacuole (GO:0006623) | 3.29768583 |
| 60 | protein targeting to lysosome (GO:0006622) | 3.29768583 |
| 61 | establishment of protein localization to vacuole (GO:0072666) | 3.29768583 |
| 62 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 3.29284595 |
| 63 | N-terminal protein amino acid acetylation (GO:0006474) | 3.26876555 |
| 64 | histone H3-K36 demethylation (GO:0070544) | 3.26042210 |
| 65 | protein targeting to Golgi (GO:0000042) | 3.22200434 |
| 66 | establishment of protein localization to Golgi (GO:0072600) | 3.21794674 |
| 67 | dendritic cell differentiation (GO:0097028) | 3.21079422 |
| 68 | negative regulation of anoikis (GO:2000811) | 3.20056192 |
| 69 | negative regulation of protein localization to cell surface (GO:2000009) | 3.18916992 |
| 70 | cellular response to exogenous dsRNA (GO:0071360) | 3.18408296 |
| 71 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.17470932 |
| 72 | mitotic cell cycle arrest (GO:0071850) | 3.16587027 |
| 73 | positive regulation of B cell differentiation (GO:0045579) | 3.12048701 |
| 74 | positive regulation of interferon-beta production (GO:0032728) | 3.09712254 |
| 75 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.08729683 |
| 76 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.08115277 |
| 77 | response to host (GO:0075136) | 3.08115277 |
| 78 | response to host defenses (GO:0052200) | 3.08115277 |
| 79 | iron ion import (GO:0097286) | 3.07401299 |
| 80 | centriole replication (GO:0007099) | 3.06937164 |
| 81 | regulation of mast cell degranulation (GO:0043304) | 3.06880779 |
| 82 | multicellular organismal reproductive behavior (GO:0033057) | 3.06268172 |
| 83 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.05646288 |
| 84 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.04018043 |
| 85 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.04018043 |
| 86 | response to exogenous dsRNA (GO:0043330) | 3.03996747 |
| 87 | urinary tract smooth muscle contraction (GO:0014848) | 3.02132854 |
| 88 | purine nucleotide transport (GO:0015865) | 3.01567857 |
| 89 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.01315092 |
| 90 | pore complex assembly (GO:0046931) | 2.99727866 |
| 91 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.99618571 |
| 92 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.99305946 |
| 93 | cellular response to interferon-beta (GO:0035458) | 2.97142613 |
| 94 | cell wall macromolecule metabolic process (GO:0044036) | 2.92149221 |
| 95 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.91970869 |
| 96 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 2.88569344 |
| 97 | regulation of glycoprotein biosynthetic process (GO:0010559) | 2.88161401 |
| 98 | aerobic respiration (GO:0009060) | 2.85765412 |
| 99 | respiratory chain complex IV assembly (GO:0008535) | 2.84216071 |
| 100 | regulation of gamma-delta T cell activation (GO:0046643) | 2.81920877 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 4.96135019 |
| 2 | GATA1_22025678_ChIP-Seq_K562_Human | 4.35423164 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.67656510 |
| 4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.49441525 |
| 5 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.20952505 |
| 6 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.08252427 |
| 7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.02419325 |
| 8 | GATA1_19941826_ChIP-Seq_K562_Human | 2.01336197 |
| 9 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.00676313 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.97031837 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.89349806 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.87661064 |
| 13 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.80236436 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.75921785 |
| 15 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.75451201 |
| 16 | TP53_16413492_ChIP-PET_HCT116_Human | 1.74629929 |
| 17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.74452263 |
| 18 | SPI1_23127762_ChIP-Seq_K562_Human | 1.65024156 |
| 19 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.64954890 |
| 20 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.60527468 |
| 21 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.60185652 |
| 22 | GATA3_26560356_Chip-Seq_TH2_Human | 1.58223373 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54307355 |
| 24 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.52932295 |
| 25 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.51528132 |
| 26 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.51302228 |
| 27 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.49415966 |
| 28 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.49415966 |
| 29 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.48054539 |
| 30 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.44180546 |
| 31 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.43830315 |
| 32 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.43488355 |
| 33 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.42822804 |
| 34 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.42814263 |
| 35 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.42670074 |
| 36 | GATA2_19941826_ChIP-Seq_K562_Human | 1.41825541 |
| 37 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.41620062 |
| 38 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.40558699 |
| 39 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.39737603 |
| 40 | STAT3_23295773_ChIP-Seq_U87_Human | 1.38037791 |
| 41 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.35124848 |
| 42 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.34753864 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.33656860 |
| 44 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.32210395 |
| 45 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.31782681 |
| 46 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.30061186 |
| 47 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.28632259 |
| 48 | VDR_22108803_ChIP-Seq_LS180_Human | 1.28237394 |
| 49 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.25801495 |
| 50 | AR_25329375_ChIP-Seq_VCAP_Human | 1.25639417 |
| 51 | MYB_26560356_Chip-Seq_TH2_Human | 1.23166935 |
| 52 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.22730900 |
| 53 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.21831083 |
| 54 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.21606457 |
| 55 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.20157921 |
| 56 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.20100805 |
| 57 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.20031340 |
| 58 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.19474388 |
| 59 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.19430519 |
| 60 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.19087497 |
| 61 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.18801818 |
| 62 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.17766667 |
| 63 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.16042406 |
| 64 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.15978988 |
| 65 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.15573099 |
| 66 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.14924417 |
| 67 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.13715436 |
| 68 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.13238937 |
| 69 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.13223119 |
| 70 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.12300945 |
| 71 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.12026074 |
| 72 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.10400899 |
| 73 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.10326677 |
| 74 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10210875 |
| 75 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.09539188 |
| 76 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.09276473 |
| 77 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.09003639 |
| 78 | EWS_26573619_Chip-Seq_HEK293_Human | 1.08779773 |
| 79 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.08515890 |
| 80 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.08365508 |
| 81 | TCF4_23295773_ChIP-Seq_U87_Human | 1.08131893 |
| 82 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.07382370 |
| 83 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06513118 |
| 84 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.06429819 |
| 85 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.05680240 |
| 86 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.05577482 |
| 87 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.04715771 |
| 88 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.03438050 |
| 89 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.02297535 |
| 90 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.01979818 |
| 91 | CJUN_26792858_Chip-Seq_BT549_Human | 1.01021575 |
| 92 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00825732 |
| 93 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.00596948 |
| 94 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.00278308 |
| 95 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.99552142 |
| 96 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.97740153 |
| 97 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.97730797 |
| 98 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.96710182 |
| 99 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96542337 |
| 100 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.96335459 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002132_abnormal_respiratory_system | 7.74576596 |
| 2 | MP0000569_abnormal_digit_pigmentation | 5.05276758 |
| 3 | MP0001661_extended_life_span | 4.23250760 |
| 4 | MP0005397_hematopoietic_system_phenotyp | 3.95793377 |
| 5 | MP0001545_abnormal_hematopoietic_system | 3.95793377 |
| 6 | MP0003787_abnormal_imprinting | 3.25966554 |
| 7 | MP0005174_abnormal_tail_pigmentation | 3.01410547 |
| 8 | MP0000015_abnormal_ear_pigmentation | 2.86774758 |
| 9 | MP0006054_spinal_hemorrhage | 2.38524090 |
| 10 | MP0003724_increased_susceptibility_to | 2.35366286 |
| 11 | MP0004883_abnormal_blood_vessel | 2.19874199 |
| 12 | MP0001853_heart_inflammation | 2.12279816 |
| 13 | MP0003950_abnormal_plasma_membrane | 2.11083952 |
| 14 | MP0004885_abnormal_endolymph | 2.05081720 |
| 15 | MP0003656_abnormal_erythrocyte_physiolo | 2.01652634 |
| 16 | MP0009697_abnormal_copulation | 2.00618445 |
| 17 | MP0008872_abnormal_physiological_respon | 1.89903368 |
| 18 | MP0008057_abnormal_DNA_replication | 1.89021452 |
| 19 | MP0005409_darkened_coat_color | 1.81315343 |
| 20 | MP0000685_abnormal_immune_system | 1.77549097 |
| 21 | MP0004484_altered_response_of | 1.74168463 |
| 22 | MP0002736_abnormal_nociception_after | 1.64693356 |
| 23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.64152723 |
| 24 | MP0005164_abnormal_response_to | 1.61533155 |
| 25 | MP0006082_CNS_inflammation | 1.59700555 |
| 26 | MP0001835_abnormal_antigen_presentation | 1.55968831 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.53868829 |
| 28 | MP0010352_gastrointestinal_tract_polyps | 1.48042792 |
| 29 | MP0001188_hyperpigmentation | 1.46391106 |
| 30 | MP0009379_abnormal_foot_pigmentation | 1.44435380 |
| 31 | MP0004782_abnormal_surfactant_physiolog | 1.39458366 |
| 32 | MP0005360_urolithiasis | 1.38832284 |
| 33 | MP0003828_pulmonary_edema | 1.37822416 |
| 34 | MP0005171_absent_coat_pigmentation | 1.36288296 |
| 35 | MP0008877_abnormal_DNA_methylation | 1.27417780 |
| 36 | MP0002723_abnormal_immune_serum | 1.25909449 |
| 37 | MP0004147_increased_porphyrin_level | 1.25047924 |
| 38 | MP0002419_abnormal_innate_immunity | 1.23915689 |
| 39 | MP0002254_reproductive_system_inflammat | 1.22415762 |
| 40 | MP0001968_abnormal_touch/_nociception | 1.22145523 |
| 41 | MP0002095_abnormal_skin_pigmentation | 1.15761439 |
| 42 | MP0009764_decreased_sensitivity_to | 1.12603021 |
| 43 | MP0005464_abnormal_platelet_physiology | 1.09847684 |
| 44 | MP0009115_abnormal_fat_cell | 1.09256083 |
| 45 | MP0005167_abnormal_blood-brain_barrier | 1.08651792 |
| 46 | MP0001800_abnormal_humoral_immune | 1.08328093 |
| 47 | MP0006138_congestive_heart_failure | 1.06955268 |
| 48 | MP0000427_abnormal_hair_cycle | 1.06553980 |
| 49 | MP0002133_abnormal_respiratory_system | 1.03061642 |
| 50 | MP0005388_respiratory_system_phenotype | 1.03061642 |
| 51 | MP0002722_abnormal_immune_system | 1.01769278 |
| 52 | MP0003303_peritoneal_inflammation | 0.99824443 |
| 53 | MP0003763_abnormal_thymus_physiology | 0.97931146 |
| 54 | MP0002452_abnormal_antigen_presenting | 0.97556285 |
| 55 | MP0006036_abnormal_mitochondrial_physio | 0.95500161 |
| 56 | MP0005636_abnormal_mineral_homeostasis | 0.93348066 |
| 57 | MP0005000_abnormal_immune_tolerance | 0.93316569 |
| 58 | MP0005376_homeostasis/metabolism_phenot | 0.92720587 |
| 59 | MP0009785_altered_susceptibility_to | 0.90605429 |
| 60 | MP0002398_abnormal_bone_marrow | 0.90369032 |
| 61 | MP0000716_abnormal_immune_system | 0.88203685 |
| 62 | MP0005025_abnormal_response_to | 0.87913855 |
| 63 | MP0003646_muscle_fatigue | 0.86944099 |
| 64 | MP0008469_abnormal_protein_level | 0.86378370 |
| 65 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.85139930 |
| 66 | MP0000689_abnormal_spleen_morphology | 0.84451545 |
| 67 | MP0003436_decreased_susceptibility_to | 0.84336975 |
| 68 | MP0005310_abnormal_salivary_gland | 0.84182161 |
| 69 | MP0004264_abnormal_extraembryonic_tissu | 0.81246066 |
| 70 | MP0002420_abnormal_adaptive_immunity | 0.80289395 |
| 71 | MP0008874_decreased_physiological_sensi | 0.78946859 |
| 72 | MP0002148_abnormal_hypersensitivity_rea | 0.78725542 |
| 73 | MP0001819_abnormal_immune_cell | 0.78608849 |
| 74 | MP0008770_decreased_survivor_rate | 0.78290133 |
| 75 | MP0001845_abnormal_inflammatory_respons | 0.75436173 |
| 76 | MP0000383_abnormal_hair_follicle | 0.74829366 |
| 77 | MP0000703_abnormal_thymus_morphology | 0.74800290 |
| 78 | MP0005387_immune_system_phenotype | 0.74660295 |
| 79 | MP0001790_abnormal_immune_system | 0.74660295 |
| 80 | MP0001915_intracranial_hemorrhage | 0.73720971 |
| 81 | MP0004142_abnormal_muscle_tone | 0.69746761 |
| 82 | MP0004084_abnormal_cardiac_muscle | 0.69638767 |
| 83 | MP0002429_abnormal_blood_cell | 0.68624455 |
| 84 | MP0002405_respiratory_system_inflammati | 0.66478815 |
| 85 | MP0000858_altered_metastatic_potential | 0.65616987 |
| 86 | MP0004043_abnormal_pH_regulation | 0.65159744 |
| 87 | MP0009278_abnormal_bone_marrow | 0.63714189 |
| 88 | MP0005253_abnormal_eye_physiology | 0.63201098 |
| 89 | MP0002177_abnormal_outer_ear | 0.61528693 |
| 90 | MP0001191_abnormal_skin_condition | 0.60063418 |
| 91 | MP0005647_abnormal_sex_gland | 0.59157452 |
| 92 | MP0003172_abnormal_lysosome_physiology | 0.58226422 |
| 93 | MP0003221_abnormal_cardiomyocyte_apopto | 0.57360750 |
| 94 | MP0004947_skin_inflammation | 0.54990358 |
| 95 | MP0000249_abnormal_blood_vessel | 0.54829365 |
| 96 | MP0005076_abnormal_cell_differentiation | 0.54151713 |
| 97 | MP0005075_abnormal_melanosome_morpholog | 0.53445691 |
| 98 | MP0001879_abnormal_lymphatic_vessel | 0.50733424 |
| 99 | MP0005395_other_phenotype | 0.50012995 |
| 100 | MP0003632_abnormal_nervous_system | 0.49800047 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Short middle phalanx of the 5th finger (HP:0004220) | 9.44123696 |
| 2 | Acanthocytosis (HP:0001927) | 7.90976745 |
| 3 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 5.88431659 |
| 4 | Petechiae (HP:0000967) | 5.42479152 |
| 5 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 5.33925031 |
| 6 | Hypoplastic iliac wings (HP:0002866) | 5.22882823 |
| 7 | Protruding tongue (HP:0010808) | 5.07869014 |
| 8 | Broad palm (HP:0001169) | 4.98966333 |
| 9 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 4.87660915 |
| 10 | Polycythemia (HP:0001901) | 4.67732268 |
| 11 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 4.48138858 |
| 12 | Prolonged bleeding time (HP:0003010) | 4.45296375 |
| 13 | Poikilocytosis (HP:0004447) | 4.37644737 |
| 14 | Absent/shortened dynein arms (HP:0200106) | 4.19155981 |
| 15 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.19155981 |
| 16 | Short 5th finger (HP:0009237) | 4.18989283 |
| 17 | Facial hemangioma (HP:0000329) | 4.13758257 |
| 18 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 4.04600737 |
| 19 | Brushfield spots (HP:0001088) | 3.99570892 |
| 20 | Abnormal platelet function (HP:0011869) | 3.87730867 |
| 21 | Impaired platelet aggregation (HP:0003540) | 3.87730867 |
| 22 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 3.86212255 |
| 23 | Abnormality of dental color (HP:0011073) | 3.53483634 |
| 24 | Reticulocytosis (HP:0001923) | 3.51379054 |
| 25 | Complete atrioventricular canal defect (HP:0001674) | 3.48195465 |
| 26 | Rectal prolapse (HP:0002035) | 3.31143004 |
| 27 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.08920505 |
| 28 | Abnormality of the wing of the ilium (HP:0011867) | 2.70515292 |
| 29 | Hypoplastic ilia (HP:0000946) | 2.62750044 |
| 30 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.61248913 |
| 31 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.60140132 |
| 32 | Conjunctival telangiectasia (HP:0000524) | 2.49019342 |
| 33 | Microtia (HP:0008551) | 2.47858271 |
| 34 | Short middle phalanx of finger (HP:0005819) | 2.45842482 |
| 35 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.42816759 |
| 36 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.42816759 |
| 37 | Abnormality of alanine metabolism (HP:0010916) | 2.41571513 |
| 38 | Hyperalaninemia (HP:0003348) | 2.41571513 |
| 39 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.41571513 |
| 40 | Abnormal ciliary motility (HP:0012262) | 2.39941052 |
| 41 | Nonimmune hydrops fetalis (HP:0001790) | 2.37091126 |
| 42 | Atrioventricular canal defect (HP:0006695) | 2.37022563 |
| 43 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.36694962 |
| 44 | Abnormality of secondary sexual hair (HP:0009888) | 2.36239345 |
| 45 | Abnormality of the axillary hair (HP:0100134) | 2.36239345 |
| 46 | Abnormality of reticulocytes (HP:0004312) | 2.30710655 |
| 47 | Epistaxis (HP:0000421) | 2.30707085 |
| 48 | Recurrent fungal infections (HP:0002841) | 2.29557432 |
| 49 | Deep palmar crease (HP:0006191) | 2.19683162 |
| 50 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.18475800 |
| 51 | Recurrent cutaneous fungal infections (HP:0011370) | 2.18475800 |
| 52 | Rhinitis (HP:0012384) | 2.14829469 |
| 53 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.14290391 |
| 54 | Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843) | 2.12404602 |
| 55 | Duodenal stenosis (HP:0100867) | 2.12344201 |
| 56 | Small intestinal stenosis (HP:0012848) | 2.12344201 |
| 57 | Eczematoid dermatitis (HP:0000976) | 2.09972426 |
| 58 | Menstrual irregularities (HP:0000858) | 2.07010879 |
| 59 | Neurodegeneration (HP:0002180) | 2.01520504 |
| 60 | Recurrent bacterial skin infections (HP:0005406) | 2.01379897 |
| 61 | Keratoconjunctivitis (HP:0001096) | 1.99266144 |
| 62 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.98297107 |
| 63 | Macroglossia (HP:0000158) | 1.98163898 |
| 64 | Type I transferrin isoform profile (HP:0003642) | 1.97437950 |
| 65 | Chronic bronchitis (HP:0004469) | 1.97183793 |
| 66 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.96875927 |
| 67 | Heterotopia (HP:0002282) | 1.94359209 |
| 68 | Abnormality of the renal collecting system (HP:0004742) | 1.92833104 |
| 69 | Abnormal sex determination (HP:0012244) | 1.88555512 |
| 70 | Sex reversal (HP:0012245) | 1.88555512 |
| 71 | Cutaneous photosensitivity (HP:0000992) | 1.88117872 |
| 72 | Duplicated collecting system (HP:0000081) | 1.87376073 |
| 73 | Cupped ear (HP:0000378) | 1.85644698 |
| 74 | Pulmonary artery stenosis (HP:0004415) | 1.84670350 |
| 75 | Supernumerary nipples (HP:0002558) | 1.81477204 |
| 76 | Neutropenia (HP:0001875) | 1.80011296 |
| 77 | Abnormality of midbrain morphology (HP:0002418) | 1.79366868 |
| 78 | Molar tooth sign on MRI (HP:0002419) | 1.79366868 |
| 79 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.77039969 |
| 80 | Spontaneous hematomas (HP:0007420) | 1.76896517 |
| 81 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.76895881 |
| 82 | Esophageal neoplasm (HP:0100751) | 1.76616417 |
| 83 | Neoplasm of head and neck (HP:0012288) | 1.76616417 |
| 84 | Optic nerve coloboma (HP:0000588) | 1.75138046 |
| 85 | Anal atresia (HP:0002023) | 1.74059687 |
| 86 | Abnormality of the middle phalanges of the hand (HP:0009833) | 1.71846302 |
| 87 | Abnormality of the acetabulum (HP:0003170) | 1.71327486 |
| 88 | Chronic hepatic failure (HP:0100626) | 1.68577933 |
| 89 | Bronchitis (HP:0012387) | 1.65302018 |
| 90 | Hepatocellular necrosis (HP:0001404) | 1.64368760 |
| 91 | Thickened nuchal skin fold (HP:0000474) | 1.64150358 |
| 92 | Abnormal biliary tract physiology (HP:0012439) | 1.63711426 |
| 93 | Bile duct proliferation (HP:0001408) | 1.63711426 |
| 94 | Low anterior hairline (HP:0000294) | 1.63527804 |
| 95 | Gingivitis (HP:0000230) | 1.63508182 |
| 96 | Abnormality of the duodenum (HP:0002246) | 1.60176319 |
| 97 | Upper motor neuron abnormality (HP:0002127) | 1.59536363 |
| 98 | Recurrent skin infections (HP:0001581) | 1.59089273 |
| 99 | Overlapping toe (HP:0001845) | 1.58583353 |
| 100 | Hematochezia (HP:0002573) | 1.57654487 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PDK2 | 6.51892972 |
| 2 | CDK12 | 6.47263087 |
| 3 | ERN1 | 3.70947096 |
| 4 | FRK | 2.41497565 |
| 5 | ARAF | 2.36817609 |
| 6 | NUAK1 | 2.31245631 |
| 7 | EIF2AK1 | 2.23848140 |
| 8 | CDK8 | 2.22121342 |
| 9 | RAF1 | 2.07974294 |
| 10 | IRAK1 | 2.04154122 |
| 11 | MAP3K1 | 2.03351580 |
| 12 | PIM2 | 2.00595111 |
| 13 | EPHA3 | 1.89976997 |
| 14 | IRAK4 | 1.81890529 |
| 15 | WNK1 | 1.80119258 |
| 16 | AKT3 | 1.75939727 |
| 17 | BRAF | 1.75761468 |
| 18 | PLK2 | 1.65280832 |
| 19 | RIPK4 | 1.61216221 |
| 20 | TEC | 1.55765847 |
| 21 | DMPK | 1.49494434 |
| 22 | BLK | 1.39226089 |
| 23 | OXSR1 | 1.38207451 |
| 24 | MAP3K2 | 1.31978608 |
| 25 | STK4 | 1.27050892 |
| 26 | PTK2B | 1.24149153 |
| 27 | CCNB1 | 1.09752157 |
| 28 | BTK | 1.08337226 |
| 29 | EPHB1 | 1.06801940 |
| 30 | SYK | 1.05599183 |
| 31 | EIF2AK3 | 1.01828847 |
| 32 | WNK3 | 0.98838108 |
| 33 | FES | 0.97787938 |
| 34 | BRSK2 | 0.97021591 |
| 35 | PRKCI | 0.96897046 |
| 36 | TRPM7 | 0.95570835 |
| 37 | PRKD1 | 0.91321995 |
| 38 | CSK | 0.88938430 |
| 39 | ITK | 0.85085611 |
| 40 | ERBB2 | 0.83863280 |
| 41 | PIK3CG | 0.83014488 |
| 42 | MAPKAPK5 | 0.81758941 |
| 43 | MAPK12 | 0.80545977 |
| 44 | TYK2 | 0.79168877 |
| 45 | NLK | 0.78932763 |
| 46 | WNK4 | 0.74864212 |
| 47 | PAK3 | 0.73455080 |
| 48 | FGFR3 | 0.73446417 |
| 49 | PDPK1 | 0.72595109 |
| 50 | BMPR1B | 0.71305584 |
| 51 | MAP2K6 | 0.70758250 |
| 52 | TAF1 | 0.70537202 |
| 53 | GRK5 | 0.69735900 |
| 54 | HCK | 0.69575345 |
| 55 | JAK2 | 0.69341262 |
| 56 | BMPR2 | 0.68368191 |
| 57 | TAOK3 | 0.67652672 |
| 58 | PDK1 | 0.64083252 |
| 59 | STK39 | 0.60578953 |
| 60 | YES1 | 0.58909220 |
| 61 | PIM1 | 0.58111162 |
| 62 | RPS6KA5 | 0.58002494 |
| 63 | MST4 | 0.56430034 |
| 64 | BRD4 | 0.55634240 |
| 65 | ACVR1B | 0.55260801 |
| 66 | ADRBK2 | 0.54655342 |
| 67 | MAP2K3 | 0.54503819 |
| 68 | IKBKE | 0.51093198 |
| 69 | SGK2 | 0.51081104 |
| 70 | FGFR4 | 0.51030156 |
| 71 | KIT | 0.51009845 |
| 72 | PRKCE | 0.50834636 |
| 73 | MAP3K7 | 0.49490610 |
| 74 | IRAK2 | 0.49018868 |
| 75 | PRKG2 | 0.47828290 |
| 76 | EEF2K | 0.47605157 |
| 77 | WEE1 | 0.46814309 |
| 78 | TXK | 0.46448043 |
| 79 | RPS6KA6 | 0.46411093 |
| 80 | MAPK13 | 0.45321620 |
| 81 | RPS6KA2 | 0.45181044 |
| 82 | AKT1 | 0.44538859 |
| 83 | NEK6 | 0.40903276 |
| 84 | LYN | 0.40499008 |
| 85 | PRKAA2 | 0.40081563 |
| 86 | EIF2AK2 | 0.39874826 |
| 87 | NTRK3 | 0.36668376 |
| 88 | RPS6KL1 | 0.35584424 |
| 89 | RPS6KC1 | 0.35584424 |
| 90 | ADRBK1 | 0.34871199 |
| 91 | LRRK2 | 0.33953038 |
| 92 | SIK2 | 0.33387745 |
| 93 | MAPK3 | 0.30943751 |
| 94 | PAK1 | 0.30301144 |
| 95 | RPS6KA1 | 0.28443327 |
| 96 | JAK3 | 0.28326965 |
| 97 | FGR | 0.27555700 |
| 98 | MAPKAPK2 | 0.27199004 |
| 99 | BCR | 0.25507191 |
| 100 | JAK1 | 0.25208760 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.68556401 |
| 2 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.54533070 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.32530049 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.30179944 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.18471187 |
| 6 | African trypanosomiasis_Homo sapiens_hsa05143 | 2.16928822 |
| 7 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.08281319 |
| 8 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.90069347 |
| 9 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.86754128 |
| 10 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.85211062 |
| 11 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.73413502 |
| 12 | Salmonella infection_Homo sapiens_hsa05132 | 1.72519031 |
| 13 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.65485922 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.65038561 |
| 15 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.63063607 |
| 16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.57641986 |
| 17 | Platelet activation_Homo sapiens_hsa04611 | 1.53241209 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.50731901 |
| 19 | Tuberculosis_Homo sapiens_hsa05152 | 1.48092125 |
| 20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.48091558 |
| 21 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.47357329 |
| 22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.47157531 |
| 23 | Legionellosis_Homo sapiens_hsa05134 | 1.41836623 |
| 24 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.35592445 |
| 25 | Hepatitis B_Homo sapiens_hsa05161 | 1.27057368 |
| 26 | Asthma_Homo sapiens_hsa05310 | 1.21270003 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.19081033 |
| 28 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.19013869 |
| 29 | ABC transporters_Homo sapiens_hsa02010 | 1.17049642 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.12554991 |
| 31 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.12151560 |
| 32 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.09262636 |
| 33 | Taste transduction_Homo sapiens_hsa04742 | 1.07492200 |
| 34 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.07058621 |
| 35 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.05521263 |
| 36 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.05075991 |
| 37 | Influenza A_Homo sapiens_hsa05164 | 1.04007960 |
| 38 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.02040515 |
| 39 | Apoptosis_Homo sapiens_hsa04210 | 1.01536411 |
| 40 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.98550142 |
| 41 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.98411588 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.98221985 |
| 43 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.97196385 |
| 44 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.93230174 |
| 45 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.93196463 |
| 46 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.91475250 |
| 47 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.91230577 |
| 48 | Measles_Homo sapiens_hsa05162 | 0.89860328 |
| 49 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.89415176 |
| 50 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.89115971 |
| 51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.88241529 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.88015110 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.87069441 |
| 54 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.86567074 |
| 55 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.85532970 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.84155668 |
| 57 | Long-term depression_Homo sapiens_hsa04730 | 0.82108572 |
| 58 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.81308595 |
| 59 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.81029619 |
| 60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.79600455 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.79244982 |
| 62 | Phagosome_Homo sapiens_hsa04145 | 0.78622641 |
| 63 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.78470745 |
| 64 | Lysine degradation_Homo sapiens_hsa00310 | 0.76154244 |
| 65 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.74767823 |
| 66 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.74160789 |
| 67 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.73833394 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.73687250 |
| 69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.72770019 |
| 70 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.71778585 |
| 71 | Mineral absorption_Homo sapiens_hsa04978 | 0.71608114 |
| 72 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.71082296 |
| 73 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.67911922 |
| 74 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.67720647 |
| 75 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.65816446 |
| 76 | Gap junction_Homo sapiens_hsa04540 | 0.64157161 |
| 77 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.63824738 |
| 78 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.60678597 |
| 79 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.60625420 |
| 80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.59641574 |
| 81 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.59621289 |
| 82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58776984 |
| 83 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.56378643 |
| 84 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.56001096 |
| 85 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.55349997 |
| 86 | Allograft rejection_Homo sapiens_hsa05330 | 0.55255363 |
| 87 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.52963921 |
| 88 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.51186027 |
| 89 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.50933267 |
| 90 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.50048296 |
| 91 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49561789 |
| 92 | Pertussis_Homo sapiens_hsa05133 | 0.48869525 |
| 93 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.47327807 |
| 94 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.46538134 |
| 95 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.46403376 |
| 96 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.44622863 |
| 97 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.41403474 |
| 98 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.41168032 |
| 99 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.40546892 |
| 100 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40466644 |

