Rank | Gene Set | Z-score |
---|---|---|
1 | DNA deamination (GO:0045006) | 4.60379321 |
2 | fucose catabolic process (GO:0019317) | 4.54179499 |
3 | L-fucose metabolic process (GO:0042354) | 4.54179499 |
4 | L-fucose catabolic process (GO:0042355) | 4.54179499 |
5 | behavioral response to nicotine (GO:0035095) | 4.36462002 |
6 | neural tube formation (GO:0001841) | 4.11089403 |
7 | DNA double-strand break processing (GO:0000729) | 3.65261795 |
8 | negative regulation of telomere maintenance (GO:0032205) | 3.42198868 |
9 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.39835331 |
10 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.39835331 |
11 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.39835331 |
12 | response to pheromone (GO:0019236) | 3.36097792 |
13 | replication fork processing (GO:0031297) | 3.35447808 |
14 | indolalkylamine metabolic process (GO:0006586) | 3.34295211 |
15 | axoneme assembly (GO:0035082) | 3.27559758 |
16 | indole-containing compound catabolic process (GO:0042436) | 3.27396092 |
17 | indolalkylamine catabolic process (GO:0046218) | 3.27396092 |
18 | tryptophan catabolic process (GO:0006569) | 3.27396092 |
19 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.23529389 |
20 | protein K11-linked deubiquitination (GO:0035871) | 3.20678487 |
21 | piRNA metabolic process (GO:0034587) | 3.14857158 |
22 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.09725058 |
23 | tryptophan metabolic process (GO:0006568) | 3.09284138 |
24 | cytochrome complex assembly (GO:0017004) | 3.06446967 |
25 | regulation of telomere maintenance (GO:0032204) | 3.06143532 |
26 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.01780953 |
27 | protein complex biogenesis (GO:0070271) | 3.01142737 |
28 | respiratory chain complex IV assembly (GO:0008535) | 3.00884459 |
29 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.00748848 |
30 | kynurenine metabolic process (GO:0070189) | 2.98703886 |
31 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.98155311 |
32 | kidney morphogenesis (GO:0060993) | 2.94927512 |
33 | recombinational repair (GO:0000725) | 2.92647611 |
34 | double-strand break repair via homologous recombination (GO:0000724) | 2.91002230 |
35 | centriole replication (GO:0007099) | 2.89160726 |
36 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.86873344 |
37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.85819032 |
38 | protein-cofactor linkage (GO:0018065) | 2.81496221 |
39 | somite rostral/caudal axis specification (GO:0032525) | 2.81472114 |
40 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.80861607 |
41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.80737892 |
42 | platelet dense granule organization (GO:0060155) | 2.78731374 |
43 | reciprocal meiotic recombination (GO:0007131) | 2.78540146 |
44 | reciprocal DNA recombination (GO:0035825) | 2.78540146 |
45 | epithelial cilium movement (GO:0003351) | 2.76577471 |
46 | DNA demethylation (GO:0080111) | 2.76454288 |
47 | negative regulation of mast cell activation (GO:0033004) | 2.73560212 |
48 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.73150433 |
49 | protein polyglutamylation (GO:0018095) | 2.73067536 |
50 | regulation of mesoderm development (GO:2000380) | 2.69269405 |
51 | signal peptide processing (GO:0006465) | 2.67556270 |
52 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.66014213 |
53 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.66014213 |
54 | NADH dehydrogenase complex assembly (GO:0010257) | 2.66014213 |
55 | maturation of 5.8S rRNA (GO:0000460) | 2.65405524 |
56 | sulfation (GO:0051923) | 2.65318788 |
57 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.64811833 |
58 | protein localization to cilium (GO:0061512) | 2.64756394 |
59 | adaptation of signaling pathway (GO:0023058) | 2.60597352 |
60 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.59190517 |
61 | cilium morphogenesis (GO:0060271) | 2.57597426 |
62 | protein K6-linked ubiquitination (GO:0085020) | 2.51946501 |
63 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.51906927 |
64 | detection of light stimulus involved in visual perception (GO:0050908) | 2.51906927 |
65 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.50985734 |
66 | regulation of memory T cell differentiation (GO:0043380) | 2.50320879 |
67 | reflex (GO:0060004) | 2.49428072 |
68 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.49341647 |
69 | mannosylation (GO:0097502) | 2.48675014 |
70 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 2.48377691 |
71 | retinal cone cell development (GO:0046549) | 2.47036934 |
72 | cellular ketone body metabolic process (GO:0046950) | 2.45936545 |
73 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.45675002 |
74 | GPI anchor metabolic process (GO:0006505) | 2.45537447 |
75 | regulation of glucokinase activity (GO:0033131) | 2.44276203 |
76 | regulation of hexokinase activity (GO:1903299) | 2.44276203 |
77 | embryonic epithelial tube formation (GO:0001838) | 2.43483579 |
78 | behavioral response to ethanol (GO:0048149) | 2.41987087 |
79 | rRNA catabolic process (GO:0016075) | 2.41907458 |
80 | neuronal action potential (GO:0019228) | 2.41782617 |
81 | activated T cell proliferation (GO:0050798) | 2.41641114 |
82 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.41374414 |
83 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.41374414 |
84 | establishment of protein localization to Golgi (GO:0072600) | 2.38595300 |
85 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.36798275 |
86 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.36798275 |
87 | cAMP catabolic process (GO:0006198) | 2.36642422 |
88 | positive regulation of mRNA catabolic process (GO:0061014) | 2.36581549 |
89 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.35489364 |
90 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.35489364 |
91 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.34842267 |
92 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.34842267 |
93 | cilium organization (GO:0044782) | 2.34189045 |
94 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.33807394 |
95 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.33807394 |
96 | indole-containing compound metabolic process (GO:0042430) | 2.33665965 |
97 | regulation of hippo signaling (GO:0035330) | 2.32684629 |
98 | gamma-aminobutyric acid transport (GO:0015812) | 2.31819210 |
99 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.31585925 |
100 | DNA integration (GO:0015074) | 2.31299066 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.56744784 |
2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.11316946 |
3 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.74148361 |
4 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.74062215 |
5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.66472591 |
6 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.63076575 |
7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.58678731 |
8 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.57038079 |
9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.50537918 |
10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.40901548 |
11 | EWS_26573619_Chip-Seq_HEK293_Human | 2.35386840 |
12 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.31563126 |
13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.23093276 |
14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21841931 |
15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.19368600 |
16 | P300_19829295_ChIP-Seq_ESCs_Human | 2.11998557 |
17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.08782667 |
18 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.07927489 |
19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04798072 |
20 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.99337919 |
21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.99185662 |
22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.96990018 |
23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.93954406 |
24 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.86914369 |
25 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.76723562 |
26 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.71833109 |
27 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.68963349 |
28 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.66752250 |
29 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.65877726 |
30 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.60492145 |
31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.58311596 |
32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.57562821 |
33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.55425250 |
34 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.53884881 |
35 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.53018559 |
36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.53007096 |
37 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.52283166 |
38 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.52089513 |
39 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.50308489 |
40 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.49186323 |
41 | STAT3_23295773_ChIP-Seq_U87_Human | 1.46129466 |
42 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.44894867 |
43 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.44894867 |
44 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.44453653 |
45 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.44453653 |
46 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.43252553 |
47 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.42775233 |
48 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.42117759 |
49 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.41821811 |
50 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40015061 |
51 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.39600345 |
52 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.33704135 |
53 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33288468 |
54 | TCF4_23295773_ChIP-Seq_U87_Human | 1.33002666 |
55 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.32217553 |
56 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.31385620 |
57 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.30106529 |
58 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.30050559 |
59 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.29952681 |
60 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.29525112 |
61 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.29074903 |
62 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.27993685 |
63 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26767556 |
64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.25827005 |
65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.25598887 |
66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.25598887 |
67 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.25429259 |
68 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.24243154 |
69 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.23196491 |
70 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.23163747 |
71 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.23025323 |
72 | * GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.21900516 |
73 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.19291166 |
74 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.18281284 |
75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.18281284 |
76 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.18218297 |
77 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.17546310 |
78 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.17346740 |
79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.16938841 |
80 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.16193414 |
81 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.16072004 |
82 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.14109226 |
83 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.13703533 |
84 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.12417802 |
85 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.12391341 |
86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.10982470 |
87 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.07530201 |
88 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.07198341 |
89 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.06172046 |
90 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.05579879 |
91 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.05185180 |
92 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03644012 |
93 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.03540606 |
94 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.02977085 |
95 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.02695054 |
96 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.02196653 |
97 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.01930918 |
98 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.01883127 |
99 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.98882678 |
100 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.97996871 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008877_abnormal_DNA_methylation | 3.30998553 |
2 | MP0000569_abnormal_digit_pigmentation | 3.03721835 |
3 | MP0002102_abnormal_ear_morphology | 2.70575734 |
4 | MP0003195_calcinosis | 2.67564473 |
5 | MP0003787_abnormal_imprinting | 2.59938475 |
6 | MP0003646_muscle_fatigue | 2.47871737 |
7 | MP0000372_irregular_coat_pigmentation | 2.41014205 |
8 | MP0006292_abnormal_olfactory_placode | 2.30638157 |
9 | MP0006072_abnormal_retinal_apoptosis | 2.17619707 |
10 | MP0008057_abnormal_DNA_replication | 2.16442046 |
11 | MP0005253_abnormal_eye_physiology | 1.94356164 |
12 | MP0005551_abnormal_eye_electrophysiolog | 1.92860702 |
13 | MP0001986_abnormal_taste_sensitivity | 1.91506543 |
14 | MP0001968_abnormal_touch/_nociception | 1.89818243 |
15 | MP0004142_abnormal_muscle_tone | 1.83767182 |
16 | MP0002638_abnormal_pupillary_reflex | 1.81819762 |
17 | MP0000427_abnormal_hair_cycle | 1.81378443 |
18 | MP0008058_abnormal_DNA_repair | 1.80057553 |
19 | MP0003880_abnormal_central_pattern | 1.74490444 |
20 | MP0002938_white_spotting | 1.71466091 |
21 | MP0005075_abnormal_melanosome_morpholog | 1.68841778 |
22 | MP0009046_muscle_twitch | 1.68125601 |
23 | MP0002736_abnormal_nociception_after | 1.67457248 |
24 | MP0002837_dystrophic_cardiac_calcinosis | 1.65887436 |
25 | MP0005645_abnormal_hypothalamus_physiol | 1.63584540 |
26 | MP0008872_abnormal_physiological_respon | 1.58690964 |
27 | MP0004043_abnormal_pH_regulation | 1.57977969 |
28 | MP0003136_yellow_coat_color | 1.54400798 |
29 | MP0002234_abnormal_pharynx_morphology | 1.53630898 |
30 | MP0004885_abnormal_endolymph | 1.48740114 |
31 | MP0009745_abnormal_behavioral_response | 1.48299644 |
32 | MP0005084_abnormal_gallbladder_morpholo | 1.47649273 |
33 | MP0004133_heterotaxia | 1.43079172 |
34 | MP0003121_genomic_imprinting | 1.41762869 |
35 | MP0000631_abnormal_neuroendocrine_gland | 1.41482227 |
36 | MP0002653_abnormal_ependyma_morphology | 1.41343549 |
37 | MP0002163_abnormal_gland_morphology | 1.37287976 |
38 | MP0006276_abnormal_autonomic_nervous | 1.35818398 |
39 | MP0008995_early_reproductive_senescence | 1.35076117 |
40 | MP0002277_abnormal_respiratory_mucosa | 1.31824169 |
41 | MP0003890_abnormal_embryonic-extraembry | 1.31326310 |
42 | MP0005646_abnormal_pituitary_gland | 1.30056864 |
43 | MP0002272_abnormal_nervous_system | 1.29828217 |
44 | MP0003011_delayed_dark_adaptation | 1.21366603 |
45 | MP0000383_abnormal_hair_follicle | 1.21206073 |
46 | MP0001486_abnormal_startle_reflex | 1.20945581 |
47 | MP0002735_abnormal_chemical_nociception | 1.19972607 |
48 | MP0005379_endocrine/exocrine_gland_phen | 1.19710356 |
49 | MP0002876_abnormal_thyroid_physiology | 1.18263301 |
50 | MP0005174_abnormal_tail_pigmentation | 1.17653904 |
51 | MP0001529_abnormal_vocalization | 1.16283368 |
52 | MP0002928_abnormal_bile_duct | 1.14496026 |
53 | MP0001501_abnormal_sleep_pattern | 1.14125899 |
54 | MP0008875_abnormal_xenobiotic_pharmacok | 1.13359324 |
55 | MP0005389_reproductive_system_phenotype | 1.11611954 |
56 | MP0002095_abnormal_skin_pigmentation | 1.11504279 |
57 | MP0001984_abnormal_olfaction | 1.10486827 |
58 | MP0004742_abnormal_vestibular_system | 1.08834305 |
59 | MP0002751_abnormal_autonomic_nervous | 1.07842571 |
60 | MP0004147_increased_porphyrin_level | 1.07738943 |
61 | MP0005671_abnormal_response_to | 1.07008485 |
62 | MP0001485_abnormal_pinna_reflex | 1.04284398 |
63 | MP0003786_premature_aging | 1.02144573 |
64 | MP0010094_abnormal_chromosome_stability | 0.98863157 |
65 | MP0004924_abnormal_behavior | 0.98792502 |
66 | MP0005386_behavior/neurological_phenoty | 0.98792502 |
67 | MP0001919_abnormal_reproductive_system | 0.96595050 |
68 | MP0002557_abnormal_social/conspecific_i | 0.96041774 |
69 | MP0004145_abnormal_muscle_electrophysio | 0.94410383 |
70 | MP0002067_abnormal_sensory_capabilities | 0.92535041 |
71 | MP0002572_abnormal_emotion/affect_behav | 0.92439011 |
72 | MP0003567_abnormal_fetal_cardiomyocyte | 0.91608731 |
73 | MP0002160_abnormal_reproductive_system | 0.90884265 |
74 | MP0003718_maternal_effect | 0.88315008 |
75 | MP0001188_hyperpigmentation | 0.87477059 |
76 | MP0001929_abnormal_gametogenesis | 0.86910449 |
77 | MP0000647_abnormal_sebaceous_gland | 0.86192372 |
78 | MP0001970_abnormal_pain_threshold | 0.84154642 |
79 | MP0002210_abnormal_sex_determination | 0.83022951 |
80 | MP0003698_abnormal_male_reproductive | 0.82879378 |
81 | MP0002138_abnormal_hepatobiliary_system | 0.82742070 |
82 | MP0005195_abnormal_posterior_eye | 0.81517122 |
83 | MP0005410_abnormal_fertilization | 0.80686514 |
84 | MP0000653_abnormal_sex_gland | 0.79045500 |
85 | MP0010386_abnormal_urinary_bladder | 0.78973530 |
86 | MP0002693_abnormal_pancreas_physiology | 0.77637644 |
87 | MP0002064_seizures | 0.76711228 |
88 | MP0002733_abnormal_thermal_nociception | 0.76140126 |
89 | MP0003119_abnormal_digestive_system | 0.75978771 |
90 | MP0008961_abnormal_basal_metabolism | 0.75370308 |
91 | MP0009697_abnormal_copulation | 0.74805663 |
92 | MP0001764_abnormal_homeostasis | 0.74691529 |
93 | MP0006035_abnormal_mitochondrial_morpho | 0.74311111 |
94 | MP0001145_abnormal_male_reproductive | 0.73240497 |
95 | MP0000516_abnormal_urinary_system | 0.72497493 |
96 | MP0005367_renal/urinary_system_phenotyp | 0.72497493 |
97 | MP0003122_maternal_imprinting | 0.72100312 |
98 | MP0002752_abnormal_somatic_nervous | 0.71811533 |
99 | MP0005391_vision/eye_phenotype | 0.71491299 |
100 | MP0003137_abnormal_impulse_conducting | 0.70782903 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pancreatic cysts (HP:0001737) | 4.17382944 |
2 | Pancreatic fibrosis (HP:0100732) | 3.75886706 |
3 | True hermaphroditism (HP:0010459) | 3.56185167 |
4 | Abnormality of midbrain morphology (HP:0002418) | 3.47632865 |
5 | Molar tooth sign on MRI (HP:0002419) | 3.47632865 |
6 | Hyperventilation (HP:0002883) | 3.41194129 |
7 | Nephronophthisis (HP:0000090) | 3.19973433 |
8 | Abnormality of the renal cortex (HP:0011035) | 3.18696216 |
9 | Congenital stationary night blindness (HP:0007642) | 3.16617026 |
10 | Medial flaring of the eyebrow (HP:0010747) | 2.91012105 |
11 | Abnormality of the renal medulla (HP:0100957) | 2.89030864 |
12 | Abolished electroretinogram (ERG) (HP:0000550) | 2.80594248 |
13 | Chronic hepatic failure (HP:0100626) | 2.79428131 |
14 | Type II lissencephaly (HP:0007260) | 2.77446816 |
15 | Renal cortical cysts (HP:0000803) | 2.67978202 |
16 | Genetic anticipation (HP:0003743) | 2.49155184 |
17 | Attenuation of retinal blood vessels (HP:0007843) | 2.47858295 |
18 | Gaze-evoked nystagmus (HP:0000640) | 2.46886838 |
19 | Pendular nystagmus (HP:0012043) | 2.35829436 |
20 | Hypothermia (HP:0002045) | 2.34998360 |
21 | Abnormality of the labia minora (HP:0012880) | 2.32164272 |
22 | Progressive cerebellar ataxia (HP:0002073) | 2.31490639 |
23 | Stomach cancer (HP:0012126) | 2.26379611 |
24 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.22759203 |
25 | Broad-based gait (HP:0002136) | 2.22425009 |
26 | Birth length less than 3rd percentile (HP:0003561) | 2.22186701 |
27 | Cystic liver disease (HP:0006706) | 2.21811764 |
28 | Gait imbalance (HP:0002141) | 2.18287933 |
29 | Congenital primary aphakia (HP:0007707) | 2.18188876 |
30 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.14166358 |
31 | Abnormality of alanine metabolism (HP:0010916) | 2.14166358 |
32 | Hyperalaninemia (HP:0003348) | 2.14166358 |
33 | Methylmalonic acidemia (HP:0002912) | 2.10740075 |
34 | Lissencephaly (HP:0001339) | 2.08874147 |
35 | Volvulus (HP:0002580) | 2.07814077 |
36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.07253339 |
37 | Thyroiditis (HP:0100646) | 2.06989125 |
38 | Cerebellar dysplasia (HP:0007033) | 2.06626349 |
39 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.04479436 |
40 | Large for gestational age (HP:0001520) | 2.03410674 |
41 | Sclerocornea (HP:0000647) | 2.03165041 |
42 | Abnormality of the pons (HP:0007361) | 2.03070982 |
43 | Nephrogenic diabetes insipidus (HP:0009806) | 2.02210972 |
44 | Tubular atrophy (HP:0000092) | 2.00364999 |
45 | Febrile seizures (HP:0002373) | 2.00055554 |
46 | Genital tract atresia (HP:0001827) | 1.99773906 |
47 | Inability to walk (HP:0002540) | 1.99736617 |
48 | Colon cancer (HP:0003003) | 1.97975673 |
49 | Bile duct proliferation (HP:0001408) | 1.96807864 |
50 | Abnormal biliary tract physiology (HP:0012439) | 1.96807864 |
51 | Pachygyria (HP:0001302) | 1.96240378 |
52 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.95940919 |
53 | Hypoplasia of the pons (HP:0012110) | 1.95249659 |
54 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.93307313 |
55 | Patellar aplasia (HP:0006443) | 1.93187459 |
56 | Anencephaly (HP:0002323) | 1.92768017 |
57 | Furrowed tongue (HP:0000221) | 1.90958933 |
58 | Fair hair (HP:0002286) | 1.90882478 |
59 | Abnormal drinking behavior (HP:0030082) | 1.88311592 |
60 | Polydipsia (HP:0001959) | 1.88311592 |
61 | Male pseudohermaphroditism (HP:0000037) | 1.87823195 |
62 | Progressive inability to walk (HP:0002505) | 1.87728459 |
63 | 3-Methylglutaconic aciduria (HP:0003535) | 1.87155500 |
64 | Increased CSF lactate (HP:0002490) | 1.86444278 |
65 | Abnormality of chromosome stability (HP:0003220) | 1.86257577 |
66 | Intestinal atresia (HP:0011100) | 1.84743223 |
67 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.84632401 |
68 | Protruding tongue (HP:0010808) | 1.83973401 |
69 | Keratoconus (HP:0000563) | 1.83097551 |
70 | Increased corneal curvature (HP:0100692) | 1.83097551 |
71 | Postaxial foot polydactyly (HP:0001830) | 1.82890304 |
72 | Vaginal atresia (HP:0000148) | 1.82122361 |
73 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.79761066 |
74 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.77620132 |
75 | Congenital hepatic fibrosis (HP:0002612) | 1.77414209 |
76 | Methylmalonic aciduria (HP:0012120) | 1.74858318 |
77 | Clubbing of toes (HP:0100760) | 1.73924212 |
78 | Abnormality of the ileum (HP:0001549) | 1.73742467 |
79 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.73511311 |
80 | Optic nerve hypoplasia (HP:0000609) | 1.73054575 |
81 | Stomatitis (HP:0010280) | 1.72893435 |
82 | Acute necrotizing encephalopathy (HP:0006965) | 1.72521719 |
83 | Mitochondrial inheritance (HP:0001427) | 1.72470903 |
84 | Disproportionate short-trunk short stature (HP:0003521) | 1.71735147 |
85 | Progressive macrocephaly (HP:0004481) | 1.71285328 |
86 | Abnormality of T cell number (HP:0011839) | 1.70892524 |
87 | IgG deficiency (HP:0004315) | 1.70503658 |
88 | Decreased central vision (HP:0007663) | 1.70483822 |
89 | Meckel diverticulum (HP:0002245) | 1.69192629 |
90 | Small hand (HP:0200055) | 1.68102800 |
91 | Constricted visual fields (HP:0001133) | 1.67671838 |
92 | Sloping forehead (HP:0000340) | 1.64975528 |
93 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.64688820 |
94 | Oligodactyly (hands) (HP:0001180) | 1.64434928 |
95 | Widely spaced teeth (HP:0000687) | 1.63782029 |
96 | Absent speech (HP:0001344) | 1.63376878 |
97 | Hypoplasia of the uterus (HP:0000013) | 1.62561824 |
98 | Dandy-Walker malformation (HP:0001305) | 1.62427689 |
99 | Short tibia (HP:0005736) | 1.61774637 |
100 | Postaxial hand polydactyly (HP:0001162) | 1.60842404 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 5.40683005 |
2 | BMPR1B | 3.38125516 |
3 | MAP4K2 | 3.20886962 |
4 | NUAK1 | 2.55754706 |
5 | WNK3 | 2.30054873 |
6 | ADRBK2 | 2.29974056 |
7 | TRIM28 | 2.26553564 |
8 | ZAK | 2.25730027 |
9 | TLK1 | 2.25454609 |
10 | ACVR1B | 2.12833783 |
11 | GRK1 | 1.93116728 |
12 | MKNK2 | 1.91286026 |
13 | TAOK3 | 1.69747900 |
14 | MAP3K4 | 1.69608301 |
15 | OXSR1 | 1.65151606 |
16 | PINK1 | 1.60738783 |
17 | MAPK13 | 1.60054597 |
18 | TXK | 1.56059000 |
19 | TNIK | 1.55595105 |
20 | CASK | 1.52725503 |
21 | INSRR | 1.51541419 |
22 | TGFBR1 | 1.40000024 |
23 | MST4 | 1.35196255 |
24 | PLK4 | 1.30397895 |
25 | PIK3CA | 1.28737271 |
26 | ERBB3 | 1.22292524 |
27 | CAMKK2 | 1.18723788 |
28 | BRSK2 | 1.18396076 |
29 | TEC | 1.10959078 |
30 | MKNK1 | 1.09774975 |
31 | NLK | 1.09120707 |
32 | EIF2AK3 | 1.09002118 |
33 | PRKCG | 1.07053782 |
34 | WNK4 | 1.05808265 |
35 | BCR | 1.05049813 |
36 | STK39 | 1.04148103 |
37 | PASK | 1.02361294 |
38 | TAF1 | 0.97312937 |
39 | PAK3 | 0.96715352 |
40 | PLK2 | 0.92354786 |
41 | WEE1 | 0.91106132 |
42 | VRK1 | 0.89697596 |
43 | PRKCE | 0.87816984 |
44 | PNCK | 0.86103087 |
45 | STK38L | 0.85747448 |
46 | CDK19 | 0.84832548 |
47 | ADRBK1 | 0.84712366 |
48 | DYRK2 | 0.83262203 |
49 | BMPR2 | 0.79998794 |
50 | PLK3 | 0.79572950 |
51 | MAP4K1 | 0.77215438 |
52 | CSNK1G1 | 0.76928185 |
53 | MARK1 | 0.76622481 |
54 | MAP2K7 | 0.75567813 |
55 | IKBKB | 0.73290139 |
56 | KIT | 0.73204922 |
57 | FGFR2 | 0.70095089 |
58 | IRAK1 | 0.68099336 |
59 | DYRK3 | 0.64573582 |
60 | FLT3 | 0.64341461 |
61 | PRKCQ | 0.62449693 |
62 | CCNB1 | 0.61334296 |
63 | CSNK1G2 | 0.61041123 |
64 | MARK3 | 0.59063320 |
65 | PRKCI | 0.59028992 |
66 | CDK8 | 0.58351348 |
67 | SRPK1 | 0.57632463 |
68 | ITK | 0.56678725 |
69 | SGK2 | 0.55388365 |
70 | STK16 | 0.54737436 |
71 | DAPK2 | 0.53324197 |
72 | AKT3 | 0.52769541 |
73 | NTRK2 | 0.51808991 |
74 | CSNK1G3 | 0.51396344 |
75 | STK3 | 0.50963189 |
76 | TIE1 | 0.48340793 |
77 | SYK | 0.47564313 |
78 | BUB1 | 0.46109206 |
79 | ATR | 0.44869532 |
80 | CDC7 | 0.44478119 |
81 | NTRK3 | 0.44164560 |
82 | STK11 | 0.42595069 |
83 | BCKDK | 0.41185330 |
84 | CSNK1A1L | 0.40587667 |
85 | ATM | 0.40325937 |
86 | RPS6KA5 | 0.40236253 |
87 | EPHA3 | 0.40106767 |
88 | PLK1 | 0.38305075 |
89 | PTK2B | 0.38043058 |
90 | YES1 | 0.37499273 |
91 | LYN | 0.37171267 |
92 | GRK7 | 0.36000807 |
93 | CSNK1A1 | 0.35704033 |
94 | CAMK2A | 0.35333001 |
95 | MAP2K6 | 0.34866352 |
96 | LCK | 0.34065251 |
97 | DYRK1A | 0.33813035 |
98 | PRKG1 | 0.33090823 |
99 | PRKACA | 0.32561981 |
100 | CHUK | 0.30534264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Phototransduction_Homo sapiens_hsa04744 | 2.49343537 |
2 | Protein export_Homo sapiens_hsa03060 | 2.46376222 |
3 | Homologous recombination_Homo sapiens_hsa03440 | 2.45974733 |
4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.42165181 |
5 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.30197116 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.28492057 |
7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.15319002 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 2.11183870 |
9 | Nicotine addiction_Homo sapiens_hsa05033 | 2.07767963 |
10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.02723855 |
11 | RNA degradation_Homo sapiens_hsa03018 | 2.00247542 |
12 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.94299086 |
13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.93863491 |
14 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.92655453 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.90327646 |
16 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.88949908 |
17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.86945114 |
18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.86069634 |
19 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.84717865 |
20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.77644296 |
21 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.77273554 |
22 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.61601792 |
23 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.61552936 |
24 | Parkinsons disease_Homo sapiens_hsa05012 | 1.55190022 |
25 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.46253282 |
26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.45898430 |
27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.44701977 |
28 | Taste transduction_Homo sapiens_hsa04742 | 1.43926400 |
29 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.41164556 |
30 | Olfactory transduction_Homo sapiens_hsa04740 | 1.39970309 |
31 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.38520910 |
32 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.34383862 |
33 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.32604878 |
34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.24591790 |
35 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.24306583 |
36 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.23275100 |
37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16207002 |
38 | Allograft rejection_Homo sapiens_hsa05330 | 1.12025778 |
39 | Morphine addiction_Homo sapiens_hsa05032 | 1.09922172 |
40 | Asthma_Homo sapiens_hsa05310 | 1.02417101 |
41 | Peroxisome_Homo sapiens_hsa04146 | 1.02168670 |
42 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.01874236 |
43 | Mismatch repair_Homo sapiens_hsa03430 | 0.99031782 |
44 | Huntingtons disease_Homo sapiens_hsa05016 | 0.99016065 |
45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.98557668 |
46 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.94291059 |
47 | Purine metabolism_Homo sapiens_hsa00230 | 0.91742769 |
48 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.91577037 |
49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.91031630 |
50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.85870588 |
51 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.85277512 |
52 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.83930297 |
53 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.83402158 |
54 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.82182567 |
55 | Alzheimers disease_Homo sapiens_hsa05010 | 0.79114879 |
56 | GABAergic synapse_Homo sapiens_hsa04727 | 0.78787455 |
57 | ABC transporters_Homo sapiens_hsa02010 | 0.77946918 |
58 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.76610579 |
59 | RNA transport_Homo sapiens_hsa03013 | 0.75235050 |
60 | Proteasome_Homo sapiens_hsa03050 | 0.75156434 |
61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.74528498 |
62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72391047 |
63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.71379559 |
64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.71203049 |
65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.71177833 |
66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.70662853 |
67 | Circadian entrainment_Homo sapiens_hsa04713 | 0.68791868 |
68 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68733479 |
69 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.67599489 |
70 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.65443019 |
71 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.65236197 |
72 | Ribosome_Homo sapiens_hsa03010 | 0.63786086 |
73 | Insulin secretion_Homo sapiens_hsa04911 | 0.62899773 |
74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62146893 |
75 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60595071 |
76 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60166848 |
77 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.60000425 |
78 | Salivary secretion_Homo sapiens_hsa04970 | 0.56687614 |
79 | Circadian rhythm_Homo sapiens_hsa04710 | 0.54010460 |
80 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.52886569 |
81 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.50598666 |
82 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.50006722 |
83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48114121 |
84 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47868269 |
85 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.46297695 |
86 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.44184967 |
87 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44046180 |
88 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.42004090 |
89 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.41329302 |
90 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.41294635 |
91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40541684 |
92 | Base excision repair_Homo sapiens_hsa03410 | 0.40335277 |
93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.40330153 |
94 | Spliceosome_Homo sapiens_hsa03040 | 0.39749067 |
95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.37800516 |
96 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.35705435 |
97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.34771929 |
98 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.32664873 |
99 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.32461690 |
100 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.31258583 |