

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neutrophil activation involved in immune response (GO:0002283) | 6.88868978 |
| 2 | response to peptidoglycan (GO:0032494) | 4.81693050 |
| 3 | modulation by symbiont of host immune response (GO:0052553) | 4.60235738 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 4.60235738 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 4.60235738 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.60235738 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.60235738 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.60235738 |
| 9 | neutrophil activation (GO:0042119) | 4.50155015 |
| 10 | negative regulation of interleukin-12 production (GO:0032695) | 4.42148601 |
| 11 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.41703250 |
| 12 | granulocyte activation (GO:0036230) | 4.37604842 |
| 13 | macrophage activation involved in immune response (GO:0002281) | 4.37190966 |
| 14 | detection of molecule of bacterial origin (GO:0032490) | 4.36677096 |
| 15 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.33512637 |
| 16 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.32643431 |
| 17 | cellular extravasation (GO:0045123) | 4.23530720 |
| 18 | positive regulation of mast cell activation (GO:0033005) | 4.11860003 |
| 19 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.95512382 |
| 20 | regulation of mast cell degranulation (GO:0043304) | 3.86476674 |
| 21 | microglial cell activation (GO:0001774) | 3.83179375 |
| 22 | immunoglobulin mediated immune response (GO:0016064) | 3.75403765 |
| 23 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.69459830 |
| 24 | negative regulation of cell killing (GO:0031342) | 3.69459830 |
| 25 | myeloid cell activation involved in immune response (GO:0002275) | 3.68999871 |
| 26 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.66950440 |
| 27 | detection of other organism (GO:0098543) | 3.66328810 |
| 28 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.64657785 |
| 29 | positive regulation of mast cell degranulation (GO:0043306) | 3.64657785 |
| 30 | detection of external biotic stimulus (GO:0098581) | 3.58520584 |
| 31 | macrophage activation (GO:0042116) | 3.57839946 |
| 32 | regulation of mast cell activation (GO:0033003) | 3.52214611 |
| 33 | regulation of platelet activation (GO:0010543) | 3.40249473 |
| 34 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.39603749 |
| 35 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.33056055 |
| 36 | regulation of platelet aggregation (GO:0090330) | 3.29801176 |
| 37 | response to host immune response (GO:0052572) | 3.29124931 |
| 38 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.29124931 |
| 39 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.29015532 |
| 40 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.26931752 |
| 41 | detection of bacterium (GO:0016045) | 3.21174228 |
| 42 | neutrophil mediated immunity (GO:0002446) | 3.20180846 |
| 43 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.19192421 |
| 44 | regulation of leukocyte degranulation (GO:0043300) | 3.17439269 |
| 45 | detection of biotic stimulus (GO:0009595) | 3.10409139 |
| 46 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.10181899 |
| 47 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.09517012 |
| 48 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.08635199 |
| 49 | negative regulation of interleukin-17 production (GO:0032700) | 3.07433095 |
| 50 | germinal center formation (GO:0002467) | 3.04690615 |
| 51 | B cell mediated immunity (GO:0019724) | 3.03956047 |
| 52 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.01347909 |
| 53 | leukocyte degranulation (GO:0043299) | 3.00359130 |
| 54 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.00093726 |
| 55 | positive regulation of leukocyte degranulation (GO:0043302) | 2.99416415 |
| 56 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.95591239 |
| 57 | adenosine receptor signaling pathway (GO:0001973) | 2.91123199 |
| 58 | T-helper 1 type immune response (GO:0042088) | 2.90212475 |
| 59 | regulation of regulatory T cell differentiation (GO:0045589) | 2.89562167 |
| 60 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.88824929 |
| 61 | myeloid leukocyte activation (GO:0002274) | 2.87790257 |
| 62 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.86817881 |
| 63 | thrombin receptor signaling pathway (GO:0070493) | 2.86592418 |
| 64 | defense response to protozoan (GO:0042832) | 2.85371331 |
| 65 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.85206897 |
| 66 | response to host (GO:0075136) | 2.85206897 |
| 67 | response to host defenses (GO:0052200) | 2.85206897 |
| 68 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.84162757 |
| 69 | phagocytosis, engulfment (GO:0006911) | 2.83750495 |
| 70 | regulation of tolerance induction (GO:0002643) | 2.82746340 |
| 71 | regulation of gamma-delta T cell activation (GO:0046643) | 2.82065585 |
| 72 | respiratory burst (GO:0045730) | 2.81534252 |
| 73 | type I interferon signaling pathway (GO:0060337) | 2.79628508 |
| 74 | cellular response to type I interferon (GO:0071357) | 2.79628508 |
| 75 | myeloid leukocyte mediated immunity (GO:0002444) | 2.79415470 |
| 76 | glycosphingolipid catabolic process (GO:0046479) | 2.78805292 |
| 77 | regulation of T cell tolerance induction (GO:0002664) | 2.77506388 |
| 78 | response to type I interferon (GO:0034340) | 2.74422485 |
| 79 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.72375581 |
| 80 | superoxide anion generation (GO:0042554) | 2.71632247 |
| 81 | neutrophil chemotaxis (GO:0030593) | 2.71277093 |
| 82 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.69025546 |
| 83 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.69025546 |
| 84 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.68626358 |
| 85 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.68034357 |
| 86 | response to protozoan (GO:0001562) | 2.66335877 |
| 87 | positive regulation of interleukin-6 production (GO:0032755) | 2.65852498 |
| 88 | positive regulation of type 2 immune response (GO:0002830) | 2.64829203 |
| 89 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.64218440 |
| 90 | neutrophil migration (GO:1990266) | 2.63410399 |
| 91 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.62684734 |
| 92 | amino sugar catabolic process (GO:0046348) | 2.62639010 |
| 93 | leukocyte aggregation (GO:0070486) | 2.62532784 |
| 94 | positive regulation of tolerance induction (GO:0002645) | 2.61271762 |
| 95 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.60457567 |
| 96 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.59435615 |
| 97 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.58251452 |
| 98 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.57103570 |
| 99 | regulation of mononuclear cell migration (GO:0071675) | 2.56241865 |
| 100 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.56133729 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.91703352 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.82938203 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.66671536 |
| 4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.71765196 |
| 5 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.59103831 |
| 6 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.43728275 |
| 7 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.37188393 |
| 8 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.23605467 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.12976744 |
| 10 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.12331818 |
| 11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.11306323 |
| 12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.10057879 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.83617819 |
| 14 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.64306628 |
| 15 | SPI1_23127762_ChIP-Seq_K562_Human | 2.55344228 |
| 16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.52115273 |
| 17 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.51646319 |
| 18 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.48166865 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.47126819 |
| 20 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.26444676 |
| 21 | * VDR_24787735_ChIP-Seq_THP-1_Human | 2.25426335 |
| 22 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.20256254 |
| 23 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.11596275 |
| 24 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.07447003 |
| 25 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.02938825 |
| 26 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.00769709 |
| 27 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.99377516 |
| 28 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.92335241 |
| 29 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.89979277 |
| 30 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.81864317 |
| 31 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.77853124 |
| 32 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.76624263 |
| 33 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72892008 |
| 34 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.71812297 |
| 35 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.71356845 |
| 36 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.69976770 |
| 37 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.68706381 |
| 38 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.68236122 |
| 39 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.66419641 |
| 40 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.66322419 |
| 41 | GATA1_22025678_ChIP-Seq_K562_Human | 1.61195903 |
| 42 | MYB_26560356_Chip-Seq_TH2_Human | 1.59206163 |
| 43 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.57791837 |
| 44 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.45644593 |
| 45 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.42738635 |
| 46 | GATA1_19941826_ChIP-Seq_K562_Human | 1.40941789 |
| 47 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.39656827 |
| 48 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.37856890 |
| 49 | GATA3_26560356_Chip-Seq_TH2_Human | 1.32783085 |
| 50 | GATA2_19941826_ChIP-Seq_K562_Human | 1.29119123 |
| 51 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.28435075 |
| 52 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.27100970 |
| 53 | * NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.24740394 |
| 54 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.19451714 |
| 55 | MYB_26560356_Chip-Seq_TH1_Human | 1.18160555 |
| 56 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.13060741 |
| 57 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.11804268 |
| 58 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11748611 |
| 59 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11205424 |
| 60 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.10982826 |
| 61 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.10863700 |
| 62 | * MAF_26560356_Chip-Seq_TH1_Human | 1.08643221 |
| 63 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.08076236 |
| 64 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07737306 |
| 65 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06522386 |
| 66 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.05554675 |
| 67 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.05104405 |
| 68 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.04454336 |
| 69 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.02394093 |
| 70 | UTX_26944678_Chip-Seq_JUKART_Human | 1.02383496 |
| 71 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98164948 |
| 72 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.97812419 |
| 73 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95991709 |
| 74 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.92402441 |
| 75 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.92402441 |
| 76 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.92031180 |
| 77 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.90975801 |
| 78 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.90119819 |
| 79 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.87866234 |
| 80 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.86743238 |
| 81 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.86620862 |
| 82 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.85032638 |
| 83 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.84615537 |
| 84 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.83629926 |
| 85 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.83454525 |
| 86 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.83383988 |
| 87 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.79692188 |
| 88 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.77368026 |
| 89 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.75807307 |
| 90 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.74915259 |
| 91 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.73392368 |
| 92 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.73244690 |
| 93 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.72474250 |
| 94 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.71684838 |
| 95 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.70006909 |
| 96 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.66639356 |
| 97 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.66580509 |
| 98 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.63376837 |
| 99 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.62707297 |
| 100 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.62383385 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.70242781 |
| 2 | MP0005464_abnormal_platelet_physiology | 3.98035629 |
| 3 | MP0003303_peritoneal_inflammation | 3.90394336 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.36304714 |
| 5 | MP0003436_decreased_susceptibility_to | 2.97153658 |
| 6 | MP0005058_abnormal_lysosome_morphology | 2.87491380 |
| 7 | MP0002419_abnormal_innate_immunity | 2.82081260 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.81357896 |
| 9 | MP0006082_CNS_inflammation | 2.76299251 |
| 10 | MP0009785_altered_susceptibility_to | 2.66840003 |
| 11 | MP0005671_abnormal_response_to | 2.43940155 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.43302410 |
| 13 | MP0008004_abnormal_stomach_pH | 2.40506107 |
| 14 | MP0005025_abnormal_response_to | 2.35283043 |
| 15 | MP0000343_altered_response_to | 2.34022947 |
| 16 | MP0003172_abnormal_lysosome_physiology | 2.29160603 |
| 17 | MP0003191_abnormal_cellular_cholesterol | 2.28659240 |
| 18 | MP0004510_myositis | 2.25545789 |
| 19 | MP0001790_abnormal_immune_system | 2.15181451 |
| 20 | MP0005387_immune_system_phenotype | 2.15181451 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.10651005 |
| 22 | MP0002723_abnormal_immune_serum | 2.10453085 |
| 23 | MP0003828_pulmonary_edema | 2.06026006 |
| 24 | MP0001800_abnormal_humoral_immune | 2.04876524 |
| 25 | MP0003300_gastrointestinal_ulcer | 2.01578700 |
| 26 | MP0009764_decreased_sensitivity_to | 1.95185848 |
| 27 | MP0005167_abnormal_blood-brain_barrier | 1.94463695 |
| 28 | MP0008260_abnormal_autophagy | 1.93900651 |
| 29 | MP0001545_abnormal_hematopoietic_system | 1.92309069 |
| 30 | MP0005397_hematopoietic_system_phenotyp | 1.92309069 |
| 31 | MP0001533_abnormal_skeleton_physiology | 1.89984761 |
| 32 | MP0002420_abnormal_adaptive_immunity | 1.85437871 |
| 33 | MP0001819_abnormal_immune_cell | 1.83203858 |
| 34 | MP0000685_abnormal_immune_system | 1.83165181 |
| 35 | MP0003075_altered_response_to | 1.76770541 |
| 36 | MP0003656_abnormal_erythrocyte_physiolo | 1.75269238 |
| 37 | MP0000465_gastrointestinal_hemorrhage | 1.75114459 |
| 38 | MP0006054_spinal_hemorrhage | 1.75010610 |
| 39 | MP0009278_abnormal_bone_marrow | 1.70241960 |
| 40 | MP0009840_abnormal_foam_cell | 1.68569700 |
| 41 | MP0001845_abnormal_inflammatory_respons | 1.66464186 |
| 42 | MP0002405_respiratory_system_inflammati | 1.58141514 |
| 43 | MP0002998_abnormal_bone_remodeling | 1.55414311 |
| 44 | MP0005451_abnormal_body_composition | 1.50317774 |
| 45 | MP0010155_abnormal_intestine_physiology | 1.47265545 |
| 46 | MP0004947_skin_inflammation | 1.39649804 |
| 47 | MP0000569_abnormal_digit_pigmentation | 1.36579429 |
| 48 | MP0008469_abnormal_protein_level | 1.36211060 |
| 49 | MP0004883_abnormal_blood_vessel | 1.32918042 |
| 50 | MP0000604_amyloidosis | 1.32575943 |
| 51 | MP0000716_abnormal_immune_system | 1.31854533 |
| 52 | MP0005310_abnormal_salivary_gland | 1.31595091 |
| 53 | MP0002398_abnormal_bone_marrow | 1.31539686 |
| 54 | MP0003183_abnormal_peptide_metabolism | 1.30549974 |
| 55 | MP0005164_abnormal_response_to | 1.28420887 |
| 56 | MP0000858_altered_metastatic_potential | 1.27547471 |
| 57 | MP0002332_abnormal_exercise_endurance | 1.25945508 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.24748921 |
| 59 | MP0001851_eye_inflammation | 1.19687153 |
| 60 | MP0000015_abnormal_ear_pigmentation | 1.17689609 |
| 61 | MP0000689_abnormal_spleen_morphology | 1.16828061 |
| 62 | MP0005166_decreased_susceptibility_to | 1.11625139 |
| 63 | MP0003448_altered_tumor_morphology | 1.10017204 |
| 64 | MP0002429_abnormal_blood_cell | 1.07169813 |
| 65 | MP0002722_abnormal_immune_system | 1.05840878 |
| 66 | MP0003690_abnormal_glial_cell | 1.05731543 |
| 67 | MP0003646_muscle_fatigue | 1.05508230 |
| 68 | MP0009333_abnormal_splenocyte_physiolog | 1.05021815 |
| 69 | MP0009763_increased_sensitivity_to | 1.00400028 |
| 70 | MP0000249_abnormal_blood_vessel | 1.00215822 |
| 71 | MP0001853_heart_inflammation | 0.99089115 |
| 72 | MP0004130_abnormal_muscle_cell | 0.91307045 |
| 73 | MP0004808_abnormal_hematopoietic_stem | 0.87136072 |
| 74 | MP0005174_abnormal_tail_pigmentation | 0.83135321 |
| 75 | MP0008874_decreased_physiological_sensi | 0.82388192 |
| 76 | MP0002132_abnormal_respiratory_system | 0.81449052 |
| 77 | MP0001542_abnormal_bone_strength | 0.80327036 |
| 78 | MP0009765_abnormal_xenobiotic_induced | 0.78549701 |
| 79 | MP0004484_altered_response_of | 0.78102280 |
| 80 | MP0003795_abnormal_bone_structure | 0.76864289 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.76097214 |
| 82 | MP0003453_abnormal_keratinocyte_physiol | 0.75298951 |
| 83 | MP0005390_skeleton_phenotype | 0.73120900 |
| 84 | MP0001663_abnormal_digestive_system | 0.70680565 |
| 85 | MP0004036_abnormal_muscle_relaxation | 0.70618121 |
| 86 | MP0003763_abnormal_thymus_physiology | 0.70101716 |
| 87 | MP0005165_increased_susceptibility_to | 0.69311307 |
| 88 | MP0003091_abnormal_cell_migration | 0.69131488 |
| 89 | MP0000920_abnormal_myelination | 0.66719099 |
| 90 | MP0005647_abnormal_sex_gland | 0.65170804 |
| 91 | MP0003045_fibrosis | 0.61562659 |
| 92 | MP0002139_abnormal_hepatobiliary_system | 0.60657631 |
| 93 | MP0005410_abnormal_fertilization | 0.60312710 |
| 94 | MP0000230_abnormal_systemic_arterial | 0.59450017 |
| 95 | MP0003221_abnormal_cardiomyocyte_apopto | 0.59082959 |
| 96 | MP0002972_abnormal_cardiac_muscle | 0.58825683 |
| 97 | MP0000703_abnormal_thymus_morphology | 0.58313899 |
| 98 | MP0005376_homeostasis/metabolism_phenot | 0.57452032 |
| 99 | MP0005319_abnormal_enzyme/_coenzyme | 0.57159404 |
| 100 | MP0004084_abnormal_cardiac_muscle | 0.57154838 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of macrophages (HP:0004311) | 5.33952864 |
| 2 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.26803740 |
| 3 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.26803740 |
| 4 | Abnormality of glycolipid metabolism (HP:0010969) | 5.26803740 |
| 5 | Recurrent abscess formation (HP:0002722) | 5.13522489 |
| 6 | Recurrent bacterial skin infections (HP:0005406) | 5.01939625 |
| 7 | Prolonged bleeding time (HP:0003010) | 4.90536114 |
| 8 | Eczematoid dermatitis (HP:0000976) | 4.86811556 |
| 9 | Petechiae (HP:0000967) | 4.66475376 |
| 10 | Stomatitis (HP:0010280) | 4.34289870 |
| 11 | Purpura (HP:0000979) | 4.29768055 |
| 12 | Epistaxis (HP:0000421) | 3.95177621 |
| 13 | Gingival bleeding (HP:0000225) | 3.86858988 |
| 14 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.86078056 |
| 15 | Spontaneous hematomas (HP:0007420) | 3.78379736 |
| 16 | Orchitis (HP:0100796) | 3.72072153 |
| 17 | Myositis (HP:0100614) | 3.67790934 |
| 18 | Optic neuritis (HP:0100653) | 3.63620704 |
| 19 | Retrobulbar optic neuritis (HP:0100654) | 3.63620704 |
| 20 | Vacuolated lymphocytes (HP:0001922) | 3.55643375 |
| 21 | Abnormal platelet volume (HP:0011876) | 3.55476684 |
| 22 | Increased cerebral lipofuscin (HP:0011813) | 3.54495165 |
| 23 | Obstructive lung disease (HP:0006536) | 3.38259902 |
| 24 | Chronic obstructive pulmonary disease (HP:0006510) | 3.38259902 |
| 25 | Disinhibition (HP:0000734) | 3.31626692 |
| 26 | Increased mean platelet volume (HP:0011877) | 3.31103283 |
| 27 | Menorrhagia (HP:0000132) | 3.25735608 |
| 28 | Dysostosis multiplex (HP:0000943) | 3.20962500 |
| 29 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 3.19366209 |
| 30 | Loss of speech (HP:0002371) | 3.11696106 |
| 31 | Recurrent skin infections (HP:0001581) | 2.97907552 |
| 32 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.90799985 |
| 33 | Mediastinal lymphadenopathy (HP:0100721) | 2.90145384 |
| 34 | Systemic lupus erythematosus (HP:0002725) | 2.89356942 |
| 35 | Conjunctival telangiectasia (HP:0000524) | 2.80822906 |
| 36 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.79194657 |
| 37 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.75630290 |
| 38 | Hepatosplenomegaly (HP:0001433) | 2.72926455 |
| 39 | Recurrent fungal infections (HP:0002841) | 2.70908824 |
| 40 | Gingivitis (HP:0000230) | 2.70792336 |
| 41 | Amyloidosis (HP:0011034) | 2.61702473 |
| 42 | Increased IgM level (HP:0003496) | 2.61470530 |
| 43 | Keratoconjunctivitis sicca (HP:0001097) | 2.58532381 |
| 44 | Arterial thrombosis (HP:0004420) | 2.57980042 |
| 45 | Chest pain (HP:0100749) | 2.55393557 |
| 46 | Encephalitis (HP:0002383) | 2.52734707 |
| 47 | Abnormal platelet function (HP:0011869) | 2.51505820 |
| 48 | Impaired platelet aggregation (HP:0003540) | 2.51505820 |
| 49 | Myocardial infarction (HP:0001658) | 2.51473013 |
| 50 | Episodic fever (HP:0001954) | 2.50997561 |
| 51 | Autoimmune thrombocytopenia (HP:0001973) | 2.46835482 |
| 52 | Meningitis (HP:0001287) | 2.41280769 |
| 53 | Urticaria (HP:0001025) | 2.35788548 |
| 54 | Keratoconjunctivitis (HP:0001096) | 2.34524026 |
| 55 | Recurrent cutaneous fungal infections (HP:0011370) | 2.32676372 |
| 56 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.32676372 |
| 57 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.31962749 |
| 58 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.31962749 |
| 59 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.31962749 |
| 60 | Vasculitis (HP:0002633) | 2.29978613 |
| 61 | Hematochezia (HP:0002573) | 2.27383492 |
| 62 | Pulmonary infiltrates (HP:0002113) | 2.25928865 |
| 63 | Increased serum ferritin (HP:0003281) | 2.25196103 |
| 64 | Abnormality of iron homeostasis (HP:0011031) | 2.25147419 |
| 65 | Hemoptysis (HP:0002105) | 2.23130834 |
| 66 | Leukocytosis (HP:0001974) | 2.20980073 |
| 67 | Hyperlipoproteinemia (HP:0010980) | 2.20510089 |
| 68 | Gastrointestinal infarctions (HP:0005244) | 2.19273284 |
| 69 | Axonal loss (HP:0003447) | 2.18741721 |
| 70 | T lymphocytopenia (HP:0005403) | 2.16345995 |
| 71 | Abnormality of lateral ventricle (HP:0030047) | 2.13745779 |
| 72 | Upper motor neuron abnormality (HP:0002127) | 2.11221718 |
| 73 | Dyschromatopsia (HP:0007641) | 2.10562907 |
| 74 | Muscle fiber splitting (HP:0003555) | 2.09928155 |
| 75 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.09339377 |
| 76 | Mucopolysacchariduria (HP:0008155) | 2.09339377 |
| 77 | Polyneuropathy (HP:0001271) | 2.08065254 |
| 78 | Abnormality of T cell number (HP:0011839) | 2.07336621 |
| 79 | Mutism (HP:0002300) | 2.05295199 |
| 80 | Polycythemia (HP:0001901) | 2.05243844 |
| 81 | Pulmonary embolism (HP:0002204) | 2.04379611 |
| 82 | Vertigo (HP:0002321) | 1.99216195 |
| 83 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.98973435 |
| 84 | Basal ganglia calcification (HP:0002135) | 1.95174500 |
| 85 | Progressive neurologic deterioration (HP:0002344) | 1.92228518 |
| 86 | Inflammation of the large intestine (HP:0002037) | 1.91945046 |
| 87 | Gangrene (HP:0100758) | 1.91354658 |
| 88 | Joint swelling (HP:0001386) | 1.90757238 |
| 89 | Recurrent viral infections (HP:0004429) | 1.89624380 |
| 90 | Paralysis (HP:0003470) | 1.89482684 |
| 91 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.86963939 |
| 92 | Osteomyelitis (HP:0002754) | 1.85256349 |
| 93 | Bruising susceptibility (HP:0000978) | 1.83509585 |
| 94 | Hypergammaglobulinemia (HP:0010702) | 1.83023966 |
| 95 | Agnosia (HP:0010524) | 1.82115022 |
| 96 | Mucosal telangiectasiae (HP:0100579) | 1.79789156 |
| 97 | Asymmetric septal hypertrophy (HP:0001670) | 1.77667208 |
| 98 | Nausea (HP:0002018) | 1.76835333 |
| 99 | Granulocytopenia (HP:0001913) | 1.76110640 |
| 100 | Abnormality of the prostate (HP:0008775) | 1.75043823 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.58986514 |
| 2 | BLK | 3.28532671 |
| 3 | MAP2K3 | 2.94441827 |
| 4 | FGR | 2.70050350 |
| 5 | IRAK3 | 2.47933307 |
| 6 | CSK | 2.38894757 |
| 7 | TYK2 | 2.35039585 |
| 8 | IRAK4 | 2.34307634 |
| 9 | ZAP70 | 2.30434080 |
| 10 | ACVR1B | 2.12578325 |
| 11 | CSF1R | 2.05657656 |
| 12 | BTK | 1.98097823 |
| 13 | MAP3K14 | 1.97926824 |
| 14 | MAP4K1 | 1.89511894 |
| 15 | FES | 1.84047837 |
| 16 | SYK | 1.81687060 |
| 17 | TXK | 1.80286229 |
| 18 | PTK2B | 1.80186906 |
| 19 | TGFBR2 | 1.79509999 |
| 20 | GRK7 | 1.77773582 |
| 21 | TNK2 | 1.77063623 |
| 22 | EPHB1 | 1.73645262 |
| 23 | BMX | 1.69452973 |
| 24 | PIK3CG | 1.66798920 |
| 25 | TAOK3 | 1.65700819 |
| 26 | HCK | 1.57777560 |
| 27 | MATK | 1.53843611 |
| 28 | JAK3 | 1.50754071 |
| 29 | LYN | 1.50517189 |
| 30 | TBK1 | 1.48712275 |
| 31 | TEC | 1.48183186 |
| 32 | MARK3 | 1.46534179 |
| 33 | BMPR2 | 1.45259600 |
| 34 | TAOK1 | 1.42725262 |
| 35 | IKBKE | 1.34180412 |
| 36 | IKBKB | 1.29697957 |
| 37 | IRAK1 | 1.21818197 |
| 38 | YES1 | 1.20423499 |
| 39 | MAP3K5 | 1.19001872 |
| 40 | MAP3K3 | 1.17736941 |
| 41 | JAK2 | 1.17588308 |
| 42 | TAOK2 | 1.15966704 |
| 43 | MAP3K1 | 1.15057388 |
| 44 | MAP3K11 | 1.07831520 |
| 45 | KIT | 1.03956538 |
| 46 | JAK1 | 1.03091726 |
| 47 | OBSCN | 1.02915068 |
| 48 | EPHA3 | 1.01822538 |
| 49 | MYLK | 0.99846570 |
| 50 | CAMKK2 | 0.98621401 |
| 51 | ERN1 | 0.94804939 |
| 52 | GRK6 | 0.94275171 |
| 53 | MAP3K6 | 0.94121514 |
| 54 | LCK | 0.93584553 |
| 55 | ADRBK2 | 0.92268947 |
| 56 | IRAK2 | 0.90918915 |
| 57 | MAP2K6 | 0.88309676 |
| 58 | MOS | 0.79886010 |
| 59 | SIK3 | 0.75312358 |
| 60 | NEK9 | 0.73648877 |
| 61 | PDK1 | 0.72894342 |
| 62 | GRK5 | 0.71731425 |
| 63 | DDR2 | 0.69236364 |
| 64 | CDC42BPA | 0.62431168 |
| 65 | MST4 | 0.61857509 |
| 66 | ITK | 0.60868217 |
| 67 | FRK | 0.59050487 |
| 68 | PDPK1 | 0.57987079 |
| 69 | MAPK12 | 0.56666624 |
| 70 | STK3 | 0.55476918 |
| 71 | KSR1 | 0.54606334 |
| 72 | MAP2K4 | 0.54396013 |
| 73 | MAP3K13 | 0.53672668 |
| 74 | PDGFRB | 0.52756849 |
| 75 | RET | 0.50676394 |
| 76 | FYN | 0.50401346 |
| 77 | PRPF4B | 0.48279453 |
| 78 | DAPK2 | 0.45816756 |
| 79 | SGK3 | 0.45179380 |
| 80 | DYRK3 | 0.42833541 |
| 81 | MARK2 | 0.42503531 |
| 82 | ABL1 | 0.42457014 |
| 83 | PRKD1 | 0.42251582 |
| 84 | MAP3K2 | 0.39102815 |
| 85 | TTN | 0.37130479 |
| 86 | ABL2 | 0.36918568 |
| 87 | PKN1 | 0.35459137 |
| 88 | PRKCQ | 0.35119714 |
| 89 | FER | 0.34889101 |
| 90 | SGK2 | 0.34709926 |
| 91 | STK10 | 0.33617180 |
| 92 | KSR2 | 0.33615535 |
| 93 | STK24 | 0.32365993 |
| 94 | PIM2 | 0.31987272 |
| 95 | PLK2 | 0.30550015 |
| 96 | DYRK1B | 0.29953178 |
| 97 | GSK3A | 0.29589290 |
| 98 | FGFR3 | 0.28409662 |
| 99 | EGFR | 0.28305923 |
| 100 | PRKG1 | 0.28243401 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.94739629 |
| 2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.85575461 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.63959975 |
| 4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.45144068 |
| 5 | Lysosome_Homo sapiens_hsa04142 | 2.29119200 |
| 6 | Tuberculosis_Homo sapiens_hsa05152 | 2.21142876 |
| 7 | Malaria_Homo sapiens_hsa05144 | 2.15343096 |
| 8 | Other glycan degradation_Homo sapiens_hsa00511 | 2.09983872 |
| 9 | Platelet activation_Homo sapiens_hsa04611 | 2.00912667 |
| 10 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.95723699 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 1.94626400 |
| 12 | Phagosome_Homo sapiens_hsa04145 | 1.92673706 |
| 13 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.88427392 |
| 14 | Legionellosis_Homo sapiens_hsa05134 | 1.84089368 |
| 15 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.81381227 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.77724824 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.73238213 |
| 18 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.67240061 |
| 19 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.65942915 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.65420599 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.64951139 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.63682443 |
| 23 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.63409013 |
| 24 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.57118564 |
| 25 | Pertussis_Homo sapiens_hsa05133 | 1.53234277 |
| 26 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.52172859 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.50958217 |
| 28 | Salmonella infection_Homo sapiens_hsa05132 | 1.50710303 |
| 29 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.47682517 |
| 30 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.47128284 |
| 31 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.44920937 |
| 32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.43402296 |
| 33 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.36052530 |
| 34 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.31849241 |
| 35 | Shigellosis_Homo sapiens_hsa05131 | 1.31206420 |
| 36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.30730350 |
| 37 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.29810433 |
| 38 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.29257804 |
| 39 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.29093462 |
| 40 | Influenza A_Homo sapiens_hsa05164 | 1.28949335 |
| 41 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.27439150 |
| 42 | Measles_Homo sapiens_hsa05162 | 1.23287121 |
| 43 | Viral myocarditis_Homo sapiens_hsa05416 | 1.23211280 |
| 44 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.21041778 |
| 45 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.20390083 |
| 46 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.18969029 |
| 47 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.14291149 |
| 48 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.12805580 |
| 49 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.11091795 |
| 50 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.10028556 |
| 51 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.09412085 |
| 52 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.97737681 |
| 53 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.94021210 |
| 54 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.86807087 |
| 55 | Hepatitis C_Homo sapiens_hsa05160 | 0.84406424 |
| 56 | Amoebiasis_Homo sapiens_hsa05146 | 0.84145400 |
| 57 | Hepatitis B_Homo sapiens_hsa05161 | 0.81593537 |
| 58 | Apoptosis_Homo sapiens_hsa04210 | 0.81180696 |
| 59 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.77872959 |
| 60 | Endocytosis_Homo sapiens_hsa04144 | 0.77073272 |
| 61 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.76988949 |
| 62 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.73902645 |
| 63 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70517988 |
| 64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69409899 |
| 65 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.68324249 |
| 66 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66560890 |
| 67 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.65872089 |
| 68 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.65504936 |
| 69 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.64907916 |
| 70 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.64880709 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63810074 |
| 72 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.58177981 |
| 73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.54614711 |
| 74 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.53762741 |
| 75 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.53647131 |
| 76 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53027899 |
| 77 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.52819530 |
| 78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52690136 |
| 79 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.51980001 |
| 80 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.51008903 |
| 81 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.46317548 |
| 82 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.46249656 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45925460 |
| 84 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.44642757 |
| 85 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.42802931 |
| 86 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.42092474 |
| 87 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.39405568 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.39355049 |
| 89 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.36811390 |
| 90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.34264739 |
| 91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32679269 |
| 92 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.32275466 |
| 93 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.30626466 |
| 94 | Galactose metabolism_Homo sapiens_hsa00052 | 0.30384450 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.29232735 |
| 96 | Insulin resistance_Homo sapiens_hsa04931 | 0.28412348 |
| 97 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.27975375 |
| 98 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.27720788 |
| 99 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.26731253 |
| 100 | Gap junction_Homo sapiens_hsa04540 | 0.26725466 |

