Rank | Gene Set | Z-score |
---|---|---|
1 | neural tube formation (GO:0001841) | 4.38718139 |
2 | indolalkylamine metabolic process (GO:0006586) | 4.19927451 |
3 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.14761783 |
4 | kynurenine metabolic process (GO:0070189) | 4.09600929 |
5 | indole-containing compound catabolic process (GO:0042436) | 4.02795929 |
6 | indolalkylamine catabolic process (GO:0046218) | 4.02795929 |
7 | tryptophan catabolic process (GO:0006569) | 4.02795929 |
8 | replication fork processing (GO:0031297) | 3.98157085 |
9 | regulation of sarcomere organization (GO:0060297) | 3.97446907 |
10 | protein K11-linked deubiquitination (GO:0035871) | 3.96809841 |
11 | DNA double-strand break processing (GO:0000729) | 3.90072971 |
12 | tryptophan metabolic process (GO:0006568) | 3.71492081 |
13 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.61593176 |
14 | signal peptide processing (GO:0006465) | 3.61504783 |
15 | tachykinin receptor signaling pathway (GO:0007217) | 3.43164055 |
16 | protein K48-linked deubiquitination (GO:0071108) | 3.43103651 |
17 | regulation of hippo signaling (GO:0035330) | 3.33622628 |
18 | behavioral response to nicotine (GO:0035095) | 3.32973092 |
19 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.32453643 |
20 | photoreceptor cell maintenance (GO:0045494) | 3.31359788 |
21 | detection of light stimulus involved in visual perception (GO:0050908) | 3.21454054 |
22 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.21454054 |
23 | recombinational repair (GO:0000725) | 3.20973856 |
24 | double-strand break repair via homologous recombination (GO:0000724) | 3.20079872 |
25 | protein prenylation (GO:0018342) | 3.14534451 |
26 | prenylation (GO:0097354) | 3.14534451 |
27 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.12442845 |
28 | positive regulation of developmental pigmentation (GO:0048087) | 3.12377588 |
29 | fucose catabolic process (GO:0019317) | 3.08804057 |
30 | L-fucose metabolic process (GO:0042354) | 3.08804057 |
31 | L-fucose catabolic process (GO:0042355) | 3.08804057 |
32 | establishment of protein localization to Golgi (GO:0072600) | 3.06952277 |
33 | retinal cone cell development (GO:0046549) | 3.04409244 |
34 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.00694278 |
35 | rRNA catabolic process (GO:0016075) | 3.00062667 |
36 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.99716692 |
37 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.98677321 |
38 | protein localization to cilium (GO:0061512) | 2.98401782 |
39 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.94498217 |
40 | regulation of gene silencing by miRNA (GO:0060964) | 2.94498217 |
41 | regulation of gene silencing by RNA (GO:0060966) | 2.94498217 |
42 | resolution of meiotic recombination intermediates (GO:0000712) | 2.93911819 |
43 | DNA deamination (GO:0045006) | 2.92118735 |
44 | behavioral response to ethanol (GO:0048149) | 2.92039032 |
45 | indole-containing compound metabolic process (GO:0042430) | 2.90130710 |
46 | protein polyglutamylation (GO:0018095) | 2.89426329 |
47 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.86886285 |
48 | axoneme assembly (GO:0035082) | 2.85066061 |
49 | reflex (GO:0060004) | 2.84489676 |
50 | interkinetic nuclear migration (GO:0022027) | 2.83149353 |
51 | microtubule anchoring (GO:0034453) | 2.80844827 |
52 | protein K63-linked deubiquitination (GO:0070536) | 2.78367840 |
53 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.78165433 |
54 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.78165433 |
55 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.78165433 |
56 | regulation of establishment of cell polarity (GO:2000114) | 2.77751117 |
57 | regulation of protein glycosylation (GO:0060049) | 2.76905527 |
58 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.76463631 |
59 | microtubule depolymerization (GO:0007019) | 2.75024926 |
60 | cornea development in camera-type eye (GO:0061303) | 2.71299250 |
61 | cilium organization (GO:0044782) | 2.71234523 |
62 | microtubule polymerization or depolymerization (GO:0031109) | 2.70574973 |
63 | reciprocal DNA recombination (GO:0035825) | 2.70498751 |
64 | reciprocal meiotic recombination (GO:0007131) | 2.70498751 |
65 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.69693119 |
66 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.69693119 |
67 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.69632310 |
68 | ncRNA catabolic process (GO:0034661) | 2.69152342 |
69 | regulation of telomere maintenance (GO:0032204) | 2.69043150 |
70 | benzene-containing compound metabolic process (GO:0042537) | 2.68269750 |
71 | mannosylation (GO:0097502) | 2.67951772 |
72 | intraciliary transport (GO:0042073) | 2.64815902 |
73 | regulation of pigment cell differentiation (GO:0050932) | 2.64556475 |
74 | DNA integration (GO:0015074) | 2.64035146 |
75 | cilium assembly (GO:0042384) | 2.63024946 |
76 | cellular ketone body metabolic process (GO:0046950) | 2.62318471 |
77 | regulation of centriole replication (GO:0046599) | 2.61689444 |
78 | respiratory chain complex IV assembly (GO:0008535) | 2.59194601 |
79 | centriole replication (GO:0007099) | 2.58180717 |
80 | cilium morphogenesis (GO:0060271) | 2.58049024 |
81 | seminiferous tubule development (GO:0072520) | 2.57022618 |
82 | protein complex biogenesis (GO:0070271) | 2.56741149 |
83 | anterograde synaptic vesicle transport (GO:0048490) | 2.55656460 |
84 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.53618860 |
85 | isotype switching (GO:0045190) | 2.53618860 |
86 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.53618860 |
87 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.53004410 |
88 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.53004410 |
89 | NADH dehydrogenase complex assembly (GO:0010257) | 2.53004410 |
90 | cellular response to sterol (GO:0036315) | 2.52352754 |
91 | peptidyl-histidine modification (GO:0018202) | 2.50875523 |
92 | DNA methylation involved in gamete generation (GO:0043046) | 2.49200685 |
93 | response to pheromone (GO:0019236) | 2.49001645 |
94 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.48016418 |
95 | histone H3-K9 methylation (GO:0051567) | 2.47602605 |
96 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.47390164 |
97 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.47390164 |
98 | acrosome assembly (GO:0001675) | 2.46807869 |
99 | negative regulation of mast cell activation (GO:0033004) | 2.46399806 |
100 | embryonic epithelial tube formation (GO:0001838) | 2.44644191 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.51342376 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.21707267 |
3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.07065501 |
4 | VDR_22108803_ChIP-Seq_LS180_Human | 2.97334778 |
5 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.89536507 |
6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.87883238 |
7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.70942117 |
8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.67679635 |
9 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.64682865 |
10 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.53392208 |
11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.52914340 |
12 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.42388439 |
13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.39169292 |
14 | FUS_26573619_Chip-Seq_HEK293_Human | 2.36855056 |
15 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.28698794 |
16 | P300_19829295_ChIP-Seq_ESCs_Human | 2.25243822 |
17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.08208279 |
18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.08080954 |
19 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 2.03006800 |
20 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.92526753 |
21 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.87999496 |
22 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.87653806 |
23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.87520789 |
24 | STAT3_23295773_ChIP-Seq_U87_Human | 1.73304647 |
25 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.69416282 |
26 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.68034662 |
27 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.67923664 |
28 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.67712321 |
29 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.66674562 |
30 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.65525660 |
31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.63556607 |
32 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.62590011 |
33 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.61051767 |
34 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.60086684 |
35 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.60086684 |
36 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.57773703 |
37 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.56379375 |
38 | TCF4_23295773_ChIP-Seq_U87_Human | 1.54691272 |
39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.51782534 |
40 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.51612009 |
41 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.50265750 |
42 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.48652598 |
43 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.48410504 |
44 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.45298044 |
45 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.44828129 |
46 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.44828129 |
47 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.44751621 |
48 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.43660908 |
49 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.43513409 |
50 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42120163 |
51 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.40998672 |
52 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.40826536 |
53 | AR_25329375_ChIP-Seq_VCAP_Human | 1.38724703 |
54 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.38435741 |
55 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.37967649 |
56 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.37519779 |
57 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.36619346 |
58 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.36024422 |
59 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.33471231 |
60 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.33242229 |
61 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.32633894 |
62 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.31052737 |
63 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30847856 |
64 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.30297450 |
65 | * NANOG_19829295_ChIP-Seq_ESCs_Human | 1.28400420 |
66 | * SOX2_19829295_ChIP-Seq_ESCs_Human | 1.28400420 |
67 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.26586150 |
68 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.26513133 |
69 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.25755107 |
70 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.25043891 |
71 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.24853794 |
72 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.22755918 |
73 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.20141607 |
74 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.19247029 |
75 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.18528278 |
76 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.18451000 |
77 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.17930353 |
78 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.17094712 |
79 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.16305193 |
80 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.15883611 |
81 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.15344966 |
82 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.13512092 |
83 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.12567428 |
84 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.11900909 |
85 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.11655298 |
86 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11384087 |
87 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.09897368 |
88 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.08731561 |
89 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.08626514 |
90 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.08136059 |
91 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.06983463 |
92 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.04811696 |
93 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.04163593 |
94 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.04011540 |
95 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.03984503 |
96 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.03156011 |
97 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.00491692 |
98 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.99146619 |
99 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.99090438 |
100 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98976588 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 3.94159932 |
2 | MP0008057_abnormal_DNA_replication | 3.60399835 |
3 | MP0008877_abnormal_DNA_methylation | 3.17233974 |
4 | MP0003646_muscle_fatigue | 2.61904936 |
5 | MP0003787_abnormal_imprinting | 2.50861011 |
6 | MP0002102_abnormal_ear_morphology | 2.47757901 |
7 | MP0005551_abnormal_eye_electrophysiolog | 2.41251781 |
8 | MP0003890_abnormal_embryonic-extraembry | 2.24878988 |
9 | MP0008058_abnormal_DNA_repair | 2.23198307 |
10 | MP0010094_abnormal_chromosome_stability | 2.07586417 |
11 | MP0003195_calcinosis | 1.97807483 |
12 | MP0005253_abnormal_eye_physiology | 1.97243044 |
13 | MP0000372_irregular_coat_pigmentation | 1.97154707 |
14 | MP0002736_abnormal_nociception_after | 1.96385498 |
15 | MP0005075_abnormal_melanosome_morpholog | 1.93819746 |
16 | MP0006072_abnormal_retinal_apoptosis | 1.89104584 |
17 | MP0006292_abnormal_olfactory_placode | 1.86606792 |
18 | MP0009046_muscle_twitch | 1.86465674 |
19 | MP0000427_abnormal_hair_cycle | 1.73258735 |
20 | MP0001968_abnormal_touch/_nociception | 1.70223174 |
21 | MP0004043_abnormal_pH_regulation | 1.69514811 |
22 | MP0002234_abnormal_pharynx_morphology | 1.68380276 |
23 | MP0008872_abnormal_physiological_respon | 1.67409188 |
24 | MP0002837_dystrophic_cardiac_calcinosis | 1.66652779 |
25 | MP0006276_abnormal_autonomic_nervous | 1.61894713 |
26 | MP0003718_maternal_effect | 1.60988222 |
27 | MP0002938_white_spotting | 1.54337218 |
28 | MP0001501_abnormal_sleep_pattern | 1.52472346 |
29 | MP0004142_abnormal_muscle_tone | 1.50530543 |
30 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46513280 |
31 | MP0003121_genomic_imprinting | 1.42334636 |
32 | MP0004215_abnormal_myocardial_fiber | 1.38964481 |
33 | MP0003937_abnormal_limbs/digits/tail_de | 1.35931355 |
34 | MP0001529_abnormal_vocalization | 1.32549126 |
35 | MP0001485_abnormal_pinna_reflex | 1.31295567 |
36 | MP0009697_abnormal_copulation | 1.29418460 |
37 | MP0000631_abnormal_neuroendocrine_gland | 1.29345370 |
38 | MP0010386_abnormal_urinary_bladder | 1.28525071 |
39 | MP0004133_heterotaxia | 1.28078957 |
40 | MP0005174_abnormal_tail_pigmentation | 1.26990053 |
41 | MP0004147_increased_porphyrin_level | 1.25926033 |
42 | MP0003786_premature_aging | 1.24890779 |
43 | MP0003880_abnormal_central_pattern | 1.24458710 |
44 | MP0003136_yellow_coat_color | 1.21250637 |
45 | MP0004145_abnormal_muscle_electrophysio | 1.20920822 |
46 | MP0005646_abnormal_pituitary_gland | 1.20699521 |
47 | MP0005645_abnormal_hypothalamus_physiol | 1.19733814 |
48 | MP0006035_abnormal_mitochondrial_morpho | 1.17705018 |
49 | MP0001293_anophthalmia | 1.13273505 |
50 | MP0002638_abnormal_pupillary_reflex | 1.12114008 |
51 | MP0002751_abnormal_autonomic_nervous | 1.10217480 |
52 | MP0002095_abnormal_skin_pigmentation | 1.08708596 |
53 | MP0004924_abnormal_behavior | 1.06147474 |
54 | MP0005386_behavior/neurological_phenoty | 1.06147474 |
55 | MP0001486_abnormal_startle_reflex | 1.05055591 |
56 | MP0005367_renal/urinary_system_phenotyp | 1.04816536 |
57 | MP0000516_abnormal_urinary_system | 1.04816536 |
58 | MP0009745_abnormal_behavioral_response | 1.04119106 |
59 | MP0002876_abnormal_thyroid_physiology | 1.02304063 |
60 | MP0005195_abnormal_posterior_eye | 1.02073201 |
61 | MP0002272_abnormal_nervous_system | 0.99830828 |
62 | MP0001984_abnormal_olfaction | 0.99618950 |
63 | MP0000383_abnormal_hair_follicle | 0.99259298 |
64 | MP0008789_abnormal_olfactory_epithelium | 0.99131442 |
65 | MP0002254_reproductive_system_inflammat | 0.98440457 |
66 | MP0008995_early_reproductive_senescence | 0.97837106 |
67 | MP0005391_vision/eye_phenotype | 0.97672853 |
68 | MP0003119_abnormal_digestive_system | 0.96656999 |
69 | MP0002160_abnormal_reproductive_system | 0.95760665 |
70 | MP0000371_diluted_coat_color | 0.95568115 |
71 | MP0001324_abnormal_eye_pigmentation | 0.95384818 |
72 | MP0000778_abnormal_nervous_system | 0.95184058 |
73 | MP0005266_abnormal_metabolism | 0.94362796 |
74 | MP0003698_abnormal_male_reproductive | 0.92488305 |
75 | MP0005395_other_phenotype | 0.92221245 |
76 | MP0005389_reproductive_system_phenotype | 0.91993558 |
77 | MP0001986_abnormal_taste_sensitivity | 0.90646152 |
78 | MP0001929_abnormal_gametogenesis | 0.86844372 |
79 | MP0002735_abnormal_chemical_nociception | 0.84855994 |
80 | MP0002752_abnormal_somatic_nervous | 0.84824417 |
81 | MP0005410_abnormal_fertilization | 0.83861272 |
82 | MP0000653_abnormal_sex_gland | 0.83709065 |
83 | MP0002067_abnormal_sensory_capabilities | 0.83579725 |
84 | MP0000538_abnormal_urinary_bladder | 0.83293984 |
85 | MP0001764_abnormal_homeostasis | 0.83138697 |
86 | MP0001919_abnormal_reproductive_system | 0.82602555 |
87 | MP0002210_abnormal_sex_determination | 0.82258466 |
88 | MP0002557_abnormal_social/conspecific_i | 0.80253180 |
89 | MP0001145_abnormal_male_reproductive | 0.79806256 |
90 | MP0002090_abnormal_vision | 0.79778801 |
91 | MP0003137_abnormal_impulse_conducting | 0.79334485 |
92 | MP0004085_abnormal_heartbeat | 0.78267930 |
93 | MP0000647_abnormal_sebaceous_gland | 0.77398828 |
94 | MP0005085_abnormal_gallbladder_physiolo | 0.76922390 |
95 | MP0000230_abnormal_systemic_arterial | 0.73628669 |
96 | MP0002184_abnormal_innervation | 0.73626570 |
97 | MP0006054_spinal_hemorrhage | 0.72501458 |
98 | MP0002233_abnormal_nose_morphology | 0.71210608 |
99 | MP0002229_neurodegeneration | 0.70534984 |
100 | MP0008775_abnormal_heart_ventricle | 0.70310810 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pancreatic cysts (HP:0001737) | 4.11100001 |
2 | Pancreatic fibrosis (HP:0100732) | 3.77582636 |
3 | True hermaphroditism (HP:0010459) | 3.70035349 |
4 | Abnormality of midbrain morphology (HP:0002418) | 3.39721809 |
5 | Molar tooth sign on MRI (HP:0002419) | 3.39721809 |
6 | Nephronophthisis (HP:0000090) | 3.28052740 |
7 | Chronic hepatic failure (HP:0100626) | 3.27612111 |
8 | Attenuation of retinal blood vessels (HP:0007843) | 3.18776456 |
9 | Abnormality of the renal cortex (HP:0011035) | 3.08635219 |
10 | Medial flaring of the eyebrow (HP:0010747) | 3.04474146 |
11 | Congenital stationary night blindness (HP:0007642) | 3.03610750 |
12 | Hyperventilation (HP:0002883) | 2.98971733 |
13 | Renal cortical cysts (HP:0000803) | 2.96229939 |
14 | Abnormality of the renal medulla (HP:0100957) | 2.92533220 |
15 | Genetic anticipation (HP:0003743) | 2.84359802 |
16 | Volvulus (HP:0002580) | 2.81932549 |
17 | Protruding tongue (HP:0010808) | 2.71442863 |
18 | Gaze-evoked nystagmus (HP:0000640) | 2.68019588 |
19 | Abolished electroretinogram (ERG) (HP:0000550) | 2.64445498 |
20 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.61358846 |
21 | Nephrogenic diabetes insipidus (HP:0009806) | 2.60268398 |
22 | Intestinal atresia (HP:0011100) | 2.56279394 |
23 | Congenital primary aphakia (HP:0007707) | 2.54529361 |
24 | Colon cancer (HP:0003003) | 2.53375488 |
25 | Chromsome breakage (HP:0040012) | 2.48684481 |
26 | Gait imbalance (HP:0002141) | 2.48037241 |
27 | Abnormality of chromosome stability (HP:0003220) | 2.47767114 |
28 | Genital tract atresia (HP:0001827) | 2.45655634 |
29 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.40379383 |
30 | Progressive inability to walk (HP:0002505) | 2.37973636 |
31 | Sclerocornea (HP:0000647) | 2.37878263 |
32 | Vaginal atresia (HP:0000148) | 2.32555152 |
33 | Cystic liver disease (HP:0006706) | 2.31243810 |
34 | Thyroiditis (HP:0100646) | 2.31079922 |
35 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.30719350 |
36 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.25896731 |
37 | Anencephaly (HP:0002323) | 2.25478364 |
38 | Postaxial foot polydactyly (HP:0001830) | 2.22641291 |
39 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.20847882 |
40 | Tubulointerstitial nephritis (HP:0001970) | 2.18066798 |
41 | Abnormality of the labia minora (HP:0012880) | 2.17118374 |
42 | Abnormality of alanine metabolism (HP:0010916) | 2.16103986 |
43 | Hyperalaninemia (HP:0003348) | 2.16103986 |
44 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.16103986 |
45 | Oligodactyly (hands) (HP:0001180) | 2.11646565 |
46 | Type II lissencephaly (HP:0007260) | 2.11047329 |
47 | Lissencephaly (HP:0001339) | 2.09311194 |
48 | Central scotoma (HP:0000603) | 2.07749286 |
49 | Sloping forehead (HP:0000340) | 2.07117802 |
50 | Neoplasm of the adrenal cortex (HP:0100641) | 2.06080194 |
51 | Inability to walk (HP:0002540) | 2.04726002 |
52 | Abnormality of the ileum (HP:0001549) | 2.04578655 |
53 | Progressive cerebellar ataxia (HP:0002073) | 2.03886833 |
54 | Increased CSF lactate (HP:0002490) | 2.02544981 |
55 | Poor coordination (HP:0002370) | 1.99385010 |
56 | Abnormality of B cell number (HP:0010975) | 1.99201546 |
57 | Small hand (HP:0200055) | 1.98040139 |
58 | Cerebellar dysplasia (HP:0007033) | 1.96994038 |
59 | Congenital hepatic fibrosis (HP:0002612) | 1.96192338 |
60 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.95177856 |
61 | Male pseudohermaphroditism (HP:0000037) | 1.94933370 |
62 | Meckel diverticulum (HP:0002245) | 1.94563491 |
63 | Fair hair (HP:0002286) | 1.92011860 |
64 | Absent speech (HP:0001344) | 1.87412399 |
65 | Facial diplegia (HP:0001349) | 1.85779854 |
66 | Astigmatism (HP:0000483) | 1.85412668 |
67 | Broad-based gait (HP:0002136) | 1.84807478 |
68 | Acute necrotizing encephalopathy (HP:0006965) | 1.84688233 |
69 | Abnormality of macular pigmentation (HP:0008002) | 1.83787724 |
70 | Increased corneal curvature (HP:0100692) | 1.81231048 |
71 | Keratoconus (HP:0000563) | 1.81231048 |
72 | Methylmalonic acidemia (HP:0002912) | 1.80596335 |
73 | Methylmalonic aciduria (HP:0012120) | 1.79583653 |
74 | Tubular atrophy (HP:0000092) | 1.78065519 |
75 | Preaxial hand polydactyly (HP:0001177) | 1.77597224 |
76 | Chorioretinal atrophy (HP:0000533) | 1.77225489 |
77 | Patellar aplasia (HP:0006443) | 1.76937269 |
78 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.76338051 |
79 | Hypoplasia of the pons (HP:0012110) | 1.76305196 |
80 | Constricted visual fields (HP:0001133) | 1.75812305 |
81 | Abnormality of the pons (HP:0007361) | 1.74932266 |
82 | Furrowed tongue (HP:0000221) | 1.74855627 |
83 | Clubbing of toes (HP:0100760) | 1.74529807 |
84 | Dandy-Walker malformation (HP:0001305) | 1.74145458 |
85 | Acute encephalopathy (HP:0006846) | 1.73099920 |
86 | Hypoplastic iliac wings (HP:0002866) | 1.73043879 |
87 | Abnormal biliary tract physiology (HP:0012439) | 1.71898701 |
88 | Bile duct proliferation (HP:0001408) | 1.71898701 |
89 | Postaxial hand polydactyly (HP:0001162) | 1.71735510 |
90 | Absent forearm bone (HP:0003953) | 1.70214861 |
91 | Aplasia involving forearm bones (HP:0009822) | 1.70214861 |
92 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.69805034 |
93 | Progressive macrocephaly (HP:0004481) | 1.69566804 |
94 | Clumsiness (HP:0002312) | 1.69286412 |
95 | Thyroid-stimulating hormone excess (HP:0002925) | 1.68454501 |
96 | Congenital sensorineural hearing impairment (HP:0008527) | 1.66773738 |
97 | B lymphocytopenia (HP:0010976) | 1.66308587 |
98 | Absent radius (HP:0003974) | 1.66127996 |
99 | Bifid tongue (HP:0010297) | 1.66021187 |
100 | Drooling (HP:0002307) | 1.65840211 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 7.67886089 |
2 | MAP4K2 | 3.33454863 |
3 | NUAK1 | 3.11927721 |
4 | WNK3 | 3.08749232 |
5 | ACVR1B | 3.07525945 |
6 | BMPR1B | 2.61484035 |
7 | TRIM28 | 2.23633958 |
8 | MAPK13 | 2.06974964 |
9 | STK38L | 2.04604703 |
10 | ADRBK2 | 2.02498851 |
11 | MKNK2 | 1.92201638 |
12 | ZAK | 1.88890556 |
13 | TAOK3 | 1.75072696 |
14 | BCR | 1.65173616 |
15 | CASK | 1.62397962 |
16 | GRK1 | 1.57381718 |
17 | ERBB3 | 1.56874498 |
18 | INSRR | 1.55406859 |
19 | BRSK2 | 1.43543462 |
20 | STK39 | 1.38004374 |
21 | OXSR1 | 1.33247611 |
22 | MKNK1 | 1.22565998 |
23 | PLK4 | 1.14604080 |
24 | TEC | 1.10997795 |
25 | PBK | 1.10711465 |
26 | TXK | 1.07810653 |
27 | PINK1 | 1.03399466 |
28 | PAK3 | 1.02332193 |
29 | MAP3K4 | 0.98238631 |
30 | EIF2AK3 | 0.97740929 |
31 | WNK4 | 0.96400978 |
32 | CSNK1G2 | 0.93404045 |
33 | ADRBK1 | 0.92270066 |
34 | AKT3 | 0.88747015 |
35 | CDC7 | 0.86958058 |
36 | FER | 0.83433747 |
37 | MARK1 | 0.83195956 |
38 | TNIK | 0.81488903 |
39 | MST4 | 0.81314358 |
40 | CSNK1G1 | 0.79662255 |
41 | PLK3 | 0.78905914 |
42 | PRKCE | 0.75920557 |
43 | PDK2 | 0.74836155 |
44 | LATS1 | 0.74208006 |
45 | NLK | 0.73835997 |
46 | CSNK1A1L | 0.73562457 |
47 | PLK2 | 0.72685641 |
48 | ATR | 0.72385531 |
49 | STK16 | 0.71816981 |
50 | SRPK1 | 0.71789055 |
51 | TAF1 | 0.70355026 |
52 | VRK1 | 0.70258233 |
53 | OBSCN | 0.69589852 |
54 | STK3 | 0.69108093 |
55 | PIK3CG | 0.67210572 |
56 | TGFBR1 | 0.66755898 |
57 | ATM | 0.66753516 |
58 | WEE1 | 0.66459352 |
59 | PIK3CA | 0.66232273 |
60 | BCKDK | 0.64808446 |
61 | PLK1 | 0.64306976 |
62 | TLK1 | 0.63433442 |
63 | NTRK3 | 0.63183556 |
64 | CSNK1G3 | 0.62428467 |
65 | FGFR2 | 0.57991358 |
66 | CAMKK2 | 0.54873452 |
67 | DYRK3 | 0.54539361 |
68 | CHEK2 | 0.54379721 |
69 | EPHA4 | 0.54120988 |
70 | BRD4 | 0.50472674 |
71 | TIE1 | 0.49484813 |
72 | NEK1 | 0.49450721 |
73 | BUB1 | 0.49258447 |
74 | CAMK4 | 0.49205173 |
75 | PRKCG | 0.47604343 |
76 | PRKAA2 | 0.46652659 |
77 | IRAK1 | 0.43001729 |
78 | PRKCQ | 0.42991632 |
79 | SGK2 | 0.42179641 |
80 | CAMK2A | 0.42154312 |
81 | EPHA3 | 0.41470522 |
82 | MAP2K7 | 0.40526907 |
83 | DYRK1A | 0.39611668 |
84 | CSNK1D | 0.38027064 |
85 | DYRK2 | 0.37598922 |
86 | FLT3 | 0.37589769 |
87 | CSNK1A1 | 0.37416918 |
88 | RPS6KA5 | 0.37299522 |
89 | ITK | 0.35309118 |
90 | PRKCB | 0.33757013 |
91 | PRKACB | 0.33477370 |
92 | VRK2 | 0.33383165 |
93 | RPS6KA4 | 0.32496601 |
94 | CDK3 | 0.32467835 |
95 | MARK3 | 0.30399776 |
96 | DAPK2 | 0.29556879 |
97 | PRKACA | 0.29149247 |
98 | PRKAA1 | 0.29024514 |
99 | CCNB1 | 0.28806530 |
100 | PKN1 | 0.28129776 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Homologous recombination_Homo sapiens_hsa03440 | 3.04125360 |
2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.00311082 |
3 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.82135863 |
4 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.82050663 |
5 | Phototransduction_Homo sapiens_hsa04744 | 2.48487021 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.40580058 |
7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.40357520 |
8 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.40142446 |
9 | RNA polymerase_Homo sapiens_hsa03020 | 2.37796860 |
10 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.95153867 |
11 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.87223162 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.86501618 |
13 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.82601565 |
14 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.76857224 |
15 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.76728327 |
16 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.76038546 |
17 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.73805908 |
18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.71640235 |
19 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.71353418 |
20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.70430595 |
21 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.69915985 |
22 | Protein export_Homo sapiens_hsa03060 | 1.69256521 |
23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.68061643 |
24 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.62717803 |
25 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.60545117 |
26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.53646207 |
27 | RNA degradation_Homo sapiens_hsa03018 | 1.53018296 |
28 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.48992035 |
29 | ABC transporters_Homo sapiens_hsa02010 | 1.48116475 |
30 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.48112681 |
31 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.38476701 |
32 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.35248956 |
33 | Mismatch repair_Homo sapiens_hsa03430 | 1.32887617 |
34 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.25715398 |
35 | Retinol metabolism_Homo sapiens_hsa00830 | 1.22499114 |
36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.21398222 |
37 | Taste transduction_Homo sapiens_hsa04742 | 1.18934601 |
38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.15173204 |
39 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.12843813 |
40 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.12769831 |
41 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.07573658 |
42 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.03511280 |
43 | Lysine degradation_Homo sapiens_hsa00310 | 1.00588687 |
44 | Peroxisome_Homo sapiens_hsa04146 | 0.95404248 |
45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.94327021 |
46 | Purine metabolism_Homo sapiens_hsa00230 | 0.94187292 |
47 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.92711800 |
48 | Morphine addiction_Homo sapiens_hsa05032 | 0.91644447 |
49 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.88752181 |
50 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.87831523 |
51 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.87371267 |
52 | RNA transport_Homo sapiens_hsa03013 | 0.85864075 |
53 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.85267574 |
54 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.85084255 |
55 | Histidine metabolism_Homo sapiens_hsa00340 | 0.84723497 |
56 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.83681046 |
57 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.81950293 |
58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.79713644 |
59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.77413685 |
60 | GABAergic synapse_Homo sapiens_hsa04727 | 0.76298777 |
61 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.75559883 |
62 | Circadian rhythm_Homo sapiens_hsa04710 | 0.74169542 |
63 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.73860588 |
64 | Huntingtons disease_Homo sapiens_hsa05016 | 0.71333645 |
65 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.71203688 |
66 | Cell cycle_Homo sapiens_hsa04110 | 0.70366513 |
67 | Circadian entrainment_Homo sapiens_hsa04713 | 0.68866501 |
68 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.67577338 |
69 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.67521786 |
70 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67175515 |
71 | Base excision repair_Homo sapiens_hsa03410 | 0.67154821 |
72 | Salivary secretion_Homo sapiens_hsa04970 | 0.66600095 |
73 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.64367433 |
74 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62438299 |
75 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.60569527 |
76 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.60182327 |
77 | Parkinsons disease_Homo sapiens_hsa05012 | 0.59688015 |
78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59262243 |
79 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.57906488 |
80 | Proteasome_Homo sapiens_hsa03050 | 0.56132313 |
81 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.53529617 |
82 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.52826010 |
83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52369775 |
84 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.45515136 |
85 | DNA replication_Homo sapiens_hsa03030 | 0.44030266 |
86 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.39811181 |
87 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.37965199 |
88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37690089 |
89 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.36682955 |
90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.36672856 |
91 | Spliceosome_Homo sapiens_hsa03040 | 0.36466325 |
92 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.36315294 |
93 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.36098619 |
94 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.36012802 |
95 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.35572688 |
96 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.33265189 |
97 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.32352869 |
98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30623560 |
99 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.30512812 |
100 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.30055516 |