

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pseudouridine synthesis (GO:0001522) | 5.17299831 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.16347462 |
| 3 | protein complex biogenesis (GO:0070271) | 5.13090224 |
| 4 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.95198335 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.86327032 |
| 6 | proteasome assembly (GO:0043248) | 4.66841551 |
| 7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.64850441 |
| 8 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.53144946 |
| 9 | NADH dehydrogenase complex assembly (GO:0010257) | 4.53144946 |
| 10 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.53144946 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.40065894 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.40065894 |
| 13 | termination of RNA polymerase III transcription (GO:0006386) | 4.38808787 |
| 14 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.38808787 |
| 15 | chaperone-mediated protein transport (GO:0072321) | 4.13989610 |
| 16 | protein-cofactor linkage (GO:0018065) | 4.01889998 |
| 17 | base-excision repair, AP site formation (GO:0006285) | 3.97982871 |
| 18 | platelet dense granule organization (GO:0060155) | 3.97554162 |
| 19 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.96833253 |
| 20 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.93739242 |
| 21 | electron transport chain (GO:0022900) | 3.91730134 |
| 22 | respiratory electron transport chain (GO:0022904) | 3.91416637 |
| 23 | maturation of 5.8S rRNA (GO:0000460) | 3.91076219 |
| 24 | DNA deamination (GO:0045006) | 3.87238731 |
| 25 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.85730424 |
| 26 | respiratory chain complex IV assembly (GO:0008535) | 3.83791738 |
| 27 | cytochrome complex assembly (GO:0017004) | 3.77007101 |
| 28 | rRNA modification (GO:0000154) | 3.64350220 |
| 29 | protein targeting to mitochondrion (GO:0006626) | 3.54828810 |
| 30 | protein K6-linked ubiquitination (GO:0085020) | 3.52296708 |
| 31 | cullin deneddylation (GO:0010388) | 3.47834252 |
| 32 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.46047809 |
| 33 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.46047809 |
| 34 | establishment of protein localization to mitochondrion (GO:0072655) | 3.41269291 |
| 35 | protein neddylation (GO:0045116) | 3.40807115 |
| 36 | peptidyl-histidine modification (GO:0018202) | 3.40677218 |
| 37 | mitochondrial RNA metabolic process (GO:0000959) | 3.36394582 |
| 38 | protein deneddylation (GO:0000338) | 3.34736965 |
| 39 | intracellular protein transmembrane import (GO:0044743) | 3.31016060 |
| 40 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.30883670 |
| 41 | tRNA processing (GO:0008033) | 3.29577965 |
| 42 | regulation of mitochondrial translation (GO:0070129) | 3.28182699 |
| 43 | protein localization to mitochondrion (GO:0070585) | 3.21633365 |
| 44 | transcription from mitochondrial promoter (GO:0006390) | 3.21227362 |
| 45 | DNA replication checkpoint (GO:0000076) | 3.20055546 |
| 46 | DNA double-strand break processing (GO:0000729) | 3.14666175 |
| 47 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.13558234 |
| 48 | protein polyglutamylation (GO:0018095) | 3.12535172 |
| 49 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.11959070 |
| 50 | replication fork processing (GO:0031297) | 3.11873007 |
| 51 | ubiquinone biosynthetic process (GO:0006744) | 3.11726769 |
| 52 | metallo-sulfur cluster assembly (GO:0031163) | 3.09908962 |
| 53 | iron-sulfur cluster assembly (GO:0016226) | 3.09908962 |
| 54 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.05854682 |
| 55 | DNA damage response, detection of DNA damage (GO:0042769) | 3.05476571 |
| 56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.99259118 |
| 57 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.93628146 |
| 58 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.93628146 |
| 59 | cellular component biogenesis (GO:0044085) | 2.89513003 |
| 60 | rRNA methylation (GO:0031167) | 2.89011361 |
| 61 | tRNA modification (GO:0006400) | 2.88802055 |
| 62 | hydrogen ion transmembrane transport (GO:1902600) | 2.88399625 |
| 63 | tRNA metabolic process (GO:0006399) | 2.87816359 |
| 64 | response to pheromone (GO:0019236) | 2.87528018 |
| 65 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.85721061 |
| 66 | rRNA processing (GO:0006364) | 2.84723015 |
| 67 | ubiquinone metabolic process (GO:0006743) | 2.83334820 |
| 68 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.82934438 |
| 69 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.82265049 |
| 70 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.82246164 |
| 71 | rRNA metabolic process (GO:0016072) | 2.82047509 |
| 72 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.80300463 |
| 73 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.79068601 |
| 74 | negative regulation of ligase activity (GO:0051352) | 2.79068601 |
| 75 | ATP biosynthetic process (GO:0006754) | 2.76456919 |
| 76 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.76435999 |
| 77 | GTP biosynthetic process (GO:0006183) | 2.76369753 |
| 78 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.73752306 |
| 79 | proton transport (GO:0015992) | 2.73603919 |
| 80 | inner mitochondrial membrane organization (GO:0007007) | 2.73464146 |
| 81 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.68777464 |
| 82 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.68265274 |
| 83 | mitochondrial transport (GO:0006839) | 2.68003620 |
| 84 | ncRNA processing (GO:0034470) | 2.67437056 |
| 85 | hydrogen transport (GO:0006818) | 2.66692163 |
| 86 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.66064464 |
| 87 | spliceosomal snRNP assembly (GO:0000387) | 2.65796552 |
| 88 | postreplication repair (GO:0006301) | 2.65768948 |
| 89 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.65669708 |
| 90 | anterograde synaptic vesicle transport (GO:0048490) | 2.64863141 |
| 91 | protein transmembrane transport (GO:0071806) | 2.64042511 |
| 92 | positive regulation of ligase activity (GO:0051351) | 2.63528157 |
| 93 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.63498007 |
| 94 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.63498007 |
| 95 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.63498007 |
| 96 | behavioral response to nicotine (GO:0035095) | 2.62353698 |
| 97 | ncRNA metabolic process (GO:0034660) | 2.61853172 |
| 98 | intracellular protein transmembrane transport (GO:0065002) | 2.61304076 |
| 99 | transcription from RNA polymerase III promoter (GO:0006383) | 2.60898076 |
| 100 | 7-methylguanosine mRNA capping (GO:0006370) | 2.60781141 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.19134097 |
| 2 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.01569549 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.60597502 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.31464748 |
| 5 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.27593304 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.11182126 |
| 7 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.76961122 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.55953569 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.88293679 |
| 10 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.72362063 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.71369625 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.69742963 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.67558645 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.64008768 |
| 15 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.63473267 |
| 16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.58989826 |
| 17 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.53394192 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.46473218 |
| 19 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.40616230 |
| 20 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.37966662 |
| 21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.29638611 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.23028632 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.08428509 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.05789893 |
| 25 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.00662344 |
| 26 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.95546172 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.92605077 |
| 28 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.90382056 |
| 29 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.90101812 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.88361856 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.79272193 |
| 32 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.79108244 |
| 33 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.70889899 |
| 34 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69869064 |
| 35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.68770614 |
| 36 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.65217133 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.63797706 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.54577447 |
| 39 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.52708586 |
| 40 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.52134592 |
| 41 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.43189235 |
| 42 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.38771959 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.35975598 |
| 44 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.35234134 |
| 45 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.34478993 |
| 46 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.33322625 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27290595 |
| 48 | EWS_26573619_Chip-Seq_HEK293_Human | 1.25252217 |
| 49 | VDR_22108803_ChIP-Seq_LS180_Human | 1.24562059 |
| 50 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.23457345 |
| 51 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.22618130 |
| 52 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.21916592 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.18536431 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.17781618 |
| 55 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.17017683 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16471692 |
| 57 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.14940354 |
| 58 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.14344287 |
| 59 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.13361678 |
| 60 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.10869357 |
| 61 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.10496980 |
| 62 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.06464465 |
| 63 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.05947715 |
| 64 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.05780001 |
| 65 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.04550846 |
| 66 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.01431591 |
| 67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.01389358 |
| 68 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.01264387 |
| 69 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.98347216 |
| 70 | FUS_26573619_Chip-Seq_HEK293_Human | 0.95019990 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.92746051 |
| 72 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.92746051 |
| 73 | AR_20517297_ChIP-Seq_VCAP_Human | 0.92710948 |
| 74 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88829553 |
| 75 | ERA_21632823_ChIP-Seq_H3396_Human | 0.88399987 |
| 76 | NCOR_22424771_ChIP-Seq_293T_Human | 0.88365341 |
| 77 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.88095079 |
| 78 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87531604 |
| 79 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.86597068 |
| 80 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.86592478 |
| 81 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.86556024 |
| 82 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.85424599 |
| 83 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.85188945 |
| 84 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.84980758 |
| 85 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84043131 |
| 86 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.83763720 |
| 87 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.82230647 |
| 88 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.82102022 |
| 89 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.81874980 |
| 90 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.80908635 |
| 91 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.79561617 |
| 92 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.78762911 |
| 93 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.77643817 |
| 94 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.77394168 |
| 95 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.76509692 |
| 96 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.76439650 |
| 97 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.76159398 |
| 98 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.75600535 |
| 99 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.74116894 |
| 100 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.72985208 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.17571437 |
| 2 | MP0003693_abnormal_embryo_hatching | 2.88158670 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 2.84651714 |
| 4 | MP0002163_abnormal_gland_morphology | 2.80480979 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.55975822 |
| 6 | MP0006036_abnormal_mitochondrial_physio | 2.50221517 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.37631294 |
| 8 | MP0005075_abnormal_melanosome_morpholog | 2.29794322 |
| 9 | MP0003786_premature_aging | 2.29600412 |
| 10 | MP0003718_maternal_effect | 2.29186981 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.21945494 |
| 12 | MP0005551_abnormal_eye_electrophysiolog | 2.02886984 |
| 13 | MP0005379_endocrine/exocrine_gland_phen | 2.00845553 |
| 14 | MP0010094_abnormal_chromosome_stability | 1.98204973 |
| 15 | MP0004142_abnormal_muscle_tone | 1.95108772 |
| 16 | MP0002102_abnormal_ear_morphology | 1.93757013 |
| 17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.91088839 |
| 18 | MP0006035_abnormal_mitochondrial_morpho | 1.89117815 |
| 19 | MP0003646_muscle_fatigue | 1.87171671 |
| 20 | MP0001968_abnormal_touch/_nociception | 1.85039367 |
| 21 | MP0002736_abnormal_nociception_after | 1.81289513 |
| 22 | MP0008872_abnormal_physiological_respon | 1.74384732 |
| 23 | MP0003186_abnormal_redox_activity | 1.73437004 |
| 24 | MP0001529_abnormal_vocalization | 1.70385819 |
| 25 | MP0009046_muscle_twitch | 1.68959082 |
| 26 | MP0004885_abnormal_endolymph | 1.68139644 |
| 27 | MP0002638_abnormal_pupillary_reflex | 1.67894031 |
| 28 | MP0002938_white_spotting | 1.67639264 |
| 29 | MP0005253_abnormal_eye_physiology | 1.65494006 |
| 30 | MP0003011_delayed_dark_adaptation | 1.65297995 |
| 31 | MP0005645_abnormal_hypothalamus_physiol | 1.63044142 |
| 32 | MP0003195_calcinosis | 1.59088474 |
| 33 | MP0004147_increased_porphyrin_level | 1.57747090 |
| 34 | MP0001905_abnormal_dopamine_level | 1.56638508 |
| 35 | MP0008789_abnormal_olfactory_epithelium | 1.51223502 |
| 36 | MP0005423_abnormal_somatic_nervous | 1.48028475 |
| 37 | MP0003111_abnormal_nucleus_morphology | 1.46376107 |
| 38 | MP0000372_irregular_coat_pigmentation | 1.44693351 |
| 39 | MP0002160_abnormal_reproductive_system | 1.44299566 |
| 40 | MP0001764_abnormal_homeostasis | 1.43237387 |
| 41 | MP0008995_early_reproductive_senescence | 1.42802260 |
| 42 | MP0001986_abnormal_taste_sensitivity | 1.41732421 |
| 43 | MP0002272_abnormal_nervous_system | 1.38589766 |
| 44 | MP0001346_abnormal_lacrimal_gland | 1.35202220 |
| 45 | MP0005084_abnormal_gallbladder_morpholo | 1.35174623 |
| 46 | MP0004957_abnormal_blastocyst_morpholog | 1.34737258 |
| 47 | MP0004133_heterotaxia | 1.33375854 |
| 48 | MP0009745_abnormal_behavioral_response | 1.31654874 |
| 49 | MP0005389_reproductive_system_phenotype | 1.29305655 |
| 50 | MP0005332_abnormal_amino_acid | 1.28187775 |
| 51 | MP0001727_abnormal_embryo_implantation | 1.25455117 |
| 52 | MP0005646_abnormal_pituitary_gland | 1.20433585 |
| 53 | MP0001919_abnormal_reproductive_system | 1.20266504 |
| 54 | MP0000015_abnormal_ear_pigmentation | 1.17750215 |
| 55 | MP0002210_abnormal_sex_determination | 1.17152319 |
| 56 | MP0008932_abnormal_embryonic_tissue | 1.15673668 |
| 57 | MP0000516_abnormal_urinary_system | 1.15404671 |
| 58 | MP0005367_renal/urinary_system_phenotyp | 1.15404671 |
| 59 | MP0001929_abnormal_gametogenesis | 1.14954313 |
| 60 | MP0005174_abnormal_tail_pigmentation | 1.13992900 |
| 61 | MP0000631_abnormal_neuroendocrine_gland | 1.11009982 |
| 62 | MP0002095_abnormal_skin_pigmentation | 1.08080614 |
| 63 | MP0000358_abnormal_cell_content/ | 1.05986949 |
| 64 | MP0002876_abnormal_thyroid_physiology | 1.05885374 |
| 65 | MP0000653_abnormal_sex_gland | 1.05432092 |
| 66 | MP0006292_abnormal_olfactory_placode | 1.03682999 |
| 67 | MP0002653_abnormal_ependyma_morphology | 1.03511854 |
| 68 | MP0001145_abnormal_male_reproductive | 1.03459227 |
| 69 | MP0001984_abnormal_olfaction | 1.02819520 |
| 70 | MP0003880_abnormal_central_pattern | 1.02697256 |
| 71 | MP0002277_abnormal_respiratory_mucosa | 1.00771902 |
| 72 | MP0003077_abnormal_cell_cycle | 0.98882798 |
| 73 | MP0003698_abnormal_male_reproductive | 0.98212012 |
| 74 | MP0003787_abnormal_imprinting | 0.98159828 |
| 75 | MP0004043_abnormal_pH_regulation | 0.97038631 |
| 76 | MP0001188_hyperpigmentation | 0.95147928 |
| 77 | MP0008007_abnormal_cellular_replicative | 0.94292736 |
| 78 | MP0002751_abnormal_autonomic_nervous | 0.93880854 |
| 79 | MP0003137_abnormal_impulse_conducting | 0.91072657 |
| 80 | MP0006276_abnormal_autonomic_nervous | 0.90185434 |
| 81 | MP0003136_yellow_coat_color | 0.88832044 |
| 82 | MP0005410_abnormal_fertilization | 0.88380213 |
| 83 | MP0004145_abnormal_muscle_electrophysio | 0.88094579 |
| 84 | MP0002572_abnormal_emotion/affect_behav | 0.85078499 |
| 85 | MP0005394_taste/olfaction_phenotype | 0.83099356 |
| 86 | MP0005499_abnormal_olfactory_system | 0.83099356 |
| 87 | MP0005195_abnormal_posterior_eye | 0.81996064 |
| 88 | MP0003121_genomic_imprinting | 0.81920155 |
| 89 | MP0002557_abnormal_social/conspecific_i | 0.79116299 |
| 90 | MP0002229_neurodegeneration | 0.78969229 |
| 91 | MP0002064_seizures | 0.78109000 |
| 92 | MP0002752_abnormal_somatic_nervous | 0.76749996 |
| 93 | MP0005395_other_phenotype | 0.74905471 |
| 94 | MP0001501_abnormal_sleep_pattern | 0.72045145 |
| 95 | MP0001963_abnormal_hearing_physiology | 0.70643891 |
| 96 | MP0000026_abnormal_inner_ear | 0.69758069 |
| 97 | MP0000538_abnormal_urinary_bladder | 0.69380696 |
| 98 | MP0010386_abnormal_urinary_bladder | 0.67269689 |
| 99 | MP0003567_abnormal_fetal_cardiomyocyte | 0.66608563 |
| 100 | MP0002735_abnormal_chemical_nociception | 0.65800357 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.75401011 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.58443174 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.31284393 |
| 4 | Increased CSF lactate (HP:0002490) | 4.16746603 |
| 5 | Acute encephalopathy (HP:0006846) | 4.05841133 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.05329085 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.66848594 |
| 8 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.58678850 |
| 9 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.58678850 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 3.53143278 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.50282328 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.45339976 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.45339976 |
| 14 | Hepatic necrosis (HP:0002605) | 3.41007828 |
| 15 | Pancreatic cysts (HP:0001737) | 3.24673790 |
| 16 | Congenital stationary night blindness (HP:0007642) | 3.16142024 |
| 17 | Increased serum lactate (HP:0002151) | 3.12187629 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.11790214 |
| 19 | Pancreatic fibrosis (HP:0100732) | 3.04794835 |
| 20 | Abnormal number of erythroid precursors (HP:0012131) | 2.95508347 |
| 21 | 3-Methylglutaconic aciduria (HP:0003535) | 2.94753441 |
| 22 | Increased intramyocellular lipid droplets (HP:0012240) | 2.91906916 |
| 23 | Nephronophthisis (HP:0000090) | 2.88676051 |
| 24 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.88264981 |
| 25 | Lactic acidosis (HP:0003128) | 2.87196847 |
| 26 | True hermaphroditism (HP:0010459) | 2.86943831 |
| 27 | Cerebral edema (HP:0002181) | 2.86618745 |
| 28 | Medial flaring of the eyebrow (HP:0010747) | 2.79131549 |
| 29 | Methylmalonic aciduria (HP:0012120) | 2.67592323 |
| 30 | Optic disc pallor (HP:0000543) | 2.57427976 |
| 31 | Absent thumb (HP:0009777) | 2.56057829 |
| 32 | Increased muscle lipid content (HP:0009058) | 2.55412526 |
| 33 | Methylmalonic acidemia (HP:0002912) | 2.50824895 |
| 34 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.49718005 |
| 35 | Reticulocytopenia (HP:0001896) | 2.49034871 |
| 36 | Respiratory failure (HP:0002878) | 2.47017216 |
| 37 | Abnormal biliary tract physiology (HP:0012439) | 2.39713418 |
| 38 | Bile duct proliferation (HP:0001408) | 2.39713418 |
| 39 | Exercise intolerance (HP:0003546) | 2.38992804 |
| 40 | Pendular nystagmus (HP:0012043) | 2.31307344 |
| 41 | Sclerocornea (HP:0000647) | 2.29598180 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.26684522 |
| 43 | Progressive inability to walk (HP:0002505) | 2.20488388 |
| 44 | Gait imbalance (HP:0002141) | 2.20083803 |
| 45 | Abnormality of the labia minora (HP:0012880) | 2.17827241 |
| 46 | Abnormality of the renal medulla (HP:0100957) | 2.16676370 |
| 47 | Abnormality of DNA repair (HP:0003254) | 2.13640911 |
| 48 | Exertional dyspnea (HP:0002875) | 2.13198294 |
| 49 | Congenital primary aphakia (HP:0007707) | 2.10684197 |
| 50 | Lethargy (HP:0001254) | 2.10289409 |
| 51 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.06108178 |
| 52 | Chronic hepatic failure (HP:0100626) | 2.05858872 |
| 53 | Hypoplasia of the pons (HP:0012110) | 2.05627855 |
| 54 | Abnormality of alanine metabolism (HP:0010916) | 2.04529681 |
| 55 | Hyperalaninemia (HP:0003348) | 2.04529681 |
| 56 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.04529681 |
| 57 | Nephrogenic diabetes insipidus (HP:0009806) | 2.02616582 |
| 58 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.01555668 |
| 59 | Attenuation of retinal blood vessels (HP:0007843) | 2.01347282 |
| 60 | Abnormality of the renal cortex (HP:0011035) | 1.98074090 |
| 61 | Type I transferrin isoform profile (HP:0003642) | 1.97727803 |
| 62 | Abnormality of urine glucose concentration (HP:0011016) | 1.96648531 |
| 63 | Glycosuria (HP:0003076) | 1.96648531 |
| 64 | Hyperglycinemia (HP:0002154) | 1.92922915 |
| 65 | Abnormal protein glycosylation (HP:0012346) | 1.92721794 |
| 66 | Abnormal glycosylation (HP:0012345) | 1.92721794 |
| 67 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.92721794 |
| 68 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.92721794 |
| 69 | Abnormality of renal resorption (HP:0011038) | 1.92259185 |
| 70 | Meckel diverticulum (HP:0002245) | 1.92227466 |
| 71 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.90417788 |
| 72 | Progressive microcephaly (HP:0000253) | 1.90173030 |
| 73 | Abnormality of the pons (HP:0007361) | 1.88994321 |
| 74 | Anencephaly (HP:0002323) | 1.88316154 |
| 75 | Abnormality of the ileum (HP:0001549) | 1.88087656 |
| 76 | Leukodystrophy (HP:0002415) | 1.87568518 |
| 77 | Renal cortical cysts (HP:0000803) | 1.82981527 |
| 78 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.82732497 |
| 79 | Tongue fasciculations (HP:0001308) | 1.82645510 |
| 80 | Retinal dysplasia (HP:0007973) | 1.81468236 |
| 81 | Hemiparesis (HP:0001269) | 1.79883548 |
| 82 | Type II lissencephaly (HP:0007260) | 1.79806794 |
| 83 | CNS demyelination (HP:0007305) | 1.79115190 |
| 84 | Colon cancer (HP:0003003) | 1.77908993 |
| 85 | Cutaneous melanoma (HP:0012056) | 1.77543949 |
| 86 | Male pseudohermaphroditism (HP:0000037) | 1.76816141 |
| 87 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.76167190 |
| 88 | Dicarboxylic aciduria (HP:0003215) | 1.76167190 |
| 89 | Chromsome breakage (HP:0040012) | 1.75918177 |
| 90 | Horseshoe kidney (HP:0000085) | 1.75629766 |
| 91 | Inability to walk (HP:0002540) | 1.73535548 |
| 92 | Polyphagia (HP:0002591) | 1.73473956 |
| 93 | Pancytopenia (HP:0001876) | 1.69676614 |
| 94 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.69298380 |
| 95 | Generalized aminoaciduria (HP:0002909) | 1.66394297 |
| 96 | Tubular atrophy (HP:0000092) | 1.66233191 |
| 97 | Patellar aplasia (HP:0006443) | 1.66160560 |
| 98 | Abolished electroretinogram (ERG) (HP:0000550) | 1.64864013 |
| 99 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.63150629 |
| 100 | Limb dystonia (HP:0002451) | 1.62699819 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.74836117 |
| 2 | ZAK | 2.91467399 |
| 3 | BUB1 | 2.80135584 |
| 4 | FRK | 2.75211810 |
| 5 | STK16 | 2.72787924 |
| 6 | NUAK1 | 2.68911567 |
| 7 | TLK1 | 2.66308584 |
| 8 | ADRBK2 | 2.44776987 |
| 9 | MUSK | 2.40377572 |
| 10 | GRK1 | 2.38398208 |
| 11 | NME1 | 2.29829076 |
| 12 | MAP4K2 | 2.25009957 |
| 13 | ACVR1B | 2.15493633 |
| 14 | VRK1 | 2.14269143 |
| 15 | PINK1 | 2.12444778 |
| 16 | BMPR1B | 2.02737398 |
| 17 | TESK2 | 1.79605562 |
| 18 | WNK3 | 1.77969732 |
| 19 | SRPK1 | 1.71385233 |
| 20 | NME2 | 1.55838773 |
| 21 | BCKDK | 1.54244857 |
| 22 | CDC7 | 1.53552032 |
| 23 | CDK8 | 1.47134266 |
| 24 | MST4 | 1.46276795 |
| 25 | PLK4 | 1.46145287 |
| 26 | PLK3 | 1.41589780 |
| 27 | PBK | 1.39420319 |
| 28 | DYRK2 | 1.38609349 |
| 29 | EIF2AK3 | 1.32345673 |
| 30 | MAP3K4 | 1.32275090 |
| 31 | EIF2AK1 | 1.29544587 |
| 32 | CSNK1G2 | 1.27770602 |
| 33 | PLK1 | 1.19450928 |
| 34 | CSNK1G3 | 1.16096621 |
| 35 | PHKG2 | 1.12341186 |
| 36 | PHKG1 | 1.12341186 |
| 37 | LIMK1 | 1.08044093 |
| 38 | CCNB1 | 1.07373252 |
| 39 | ERBB3 | 1.03905527 |
| 40 | PDK2 | 1.02784997 |
| 41 | TAF1 | 1.01673861 |
| 42 | TSSK6 | 0.99192528 |
| 43 | WNK4 | 0.98966886 |
| 44 | ATR | 0.97181543 |
| 45 | ABL2 | 0.95790808 |
| 46 | PIM2 | 0.94896636 |
| 47 | CHEK2 | 0.94727510 |
| 48 | CSNK1G1 | 0.94243918 |
| 49 | MAPK13 | 0.90332860 |
| 50 | MAP2K7 | 0.89869934 |
| 51 | ADRBK1 | 0.86925641 |
| 52 | AURKA | 0.86235902 |
| 53 | PRKCG | 0.84780251 |
| 54 | TRIM28 | 0.83048583 |
| 55 | CSNK1A1L | 0.81838654 |
| 56 | TXK | 0.80235856 |
| 57 | OXSR1 | 0.79380105 |
| 58 | RPS6KA5 | 0.76702879 |
| 59 | MAPKAPK3 | 0.74950406 |
| 60 | DAPK1 | 0.74891860 |
| 61 | TIE1 | 0.74440650 |
| 62 | TAOK3 | 0.73904512 |
| 63 | PRKCI | 0.69349483 |
| 64 | MKNK2 | 0.68831787 |
| 65 | IKBKB | 0.68642490 |
| 66 | MAPK15 | 0.66486133 |
| 67 | INSRR | 0.58654273 |
| 68 | TTK | 0.58290611 |
| 69 | PKN1 | 0.58020910 |
| 70 | PASK | 0.57003522 |
| 71 | STK39 | 0.56147115 |
| 72 | DAPK2 | 0.55102937 |
| 73 | AURKB | 0.53080797 |
| 74 | GRK7 | 0.52990919 |
| 75 | TGFBR1 | 0.50385947 |
| 76 | GRK5 | 0.49456151 |
| 77 | CSNK2A1 | 0.49438352 |
| 78 | PAK3 | 0.47765792 |
| 79 | KDR | 0.47754699 |
| 80 | EIF2AK2 | 0.46724857 |
| 81 | PRKCE | 0.46501261 |
| 82 | WEE1 | 0.45370294 |
| 83 | PNCK | 0.43842614 |
| 84 | NEK1 | 0.43733315 |
| 85 | CSNK1A1 | 0.43210642 |
| 86 | MAP2K2 | 0.40803872 |
| 87 | CDK19 | 0.40402460 |
| 88 | CSNK2A2 | 0.39972481 |
| 89 | PLK2 | 0.39966012 |
| 90 | ATM | 0.39364931 |
| 91 | MAPKAPK5 | 0.39357730 |
| 92 | DAPK3 | 0.37701741 |
| 93 | MAP2K6 | 0.36005215 |
| 94 | ILK | 0.35718498 |
| 95 | MAP3K12 | 0.35221234 |
| 96 | TEC | 0.35061255 |
| 97 | PRKACA | 0.33590387 |
| 98 | PRKCQ | 0.31960625 |
| 99 | PRKCA | 0.30840755 |
| 100 | CHEK1 | 0.30748745 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.95168874 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.48829096 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.37764922 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.22783105 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.77168110 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.61903115 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.55402520 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.37836010 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.29905686 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.21772976 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 2.06372282 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.05553559 |
| 13 | Sulfur relay system_Homo sapiens_hsa04122 | 2.00874360 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.94410215 |
| 15 | Base excision repair_Homo sapiens_hsa03410 | 1.92030724 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.85199745 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.84940958 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.81899915 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.76850247 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.76531587 |
| 21 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.75423098 |
| 22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.69884564 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.69170883 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.48967872 |
| 25 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.48208229 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.46999656 |
| 27 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.46466801 |
| 28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.46072481 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.38398058 |
| 30 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.37785215 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.37404475 |
| 32 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.33153982 |
| 33 | Phototransduction_Homo sapiens_hsa04744 | 1.29932948 |
| 34 | Purine metabolism_Homo sapiens_hsa00230 | 1.28345915 |
| 35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.27602506 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.26358572 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.25914486 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.23346654 |
| 39 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.17974912 |
| 40 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.15458616 |
| 41 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.15180381 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 1.14397932 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 1.13263094 |
| 44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.13103498 |
| 45 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.10035001 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.09734409 |
| 47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.04683704 |
| 48 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01435973 |
| 49 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.97996709 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.93686996 |
| 51 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.88057855 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.87791194 |
| 53 | Metabolic pathways_Homo sapiens_hsa01100 | 0.87262185 |
| 54 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.84772838 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82052412 |
| 56 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.77988287 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74528370 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.73672581 |
| 59 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73331388 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.73290794 |
| 61 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.72844400 |
| 62 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.68998981 |
| 63 | Nicotine addiction_Homo sapiens_hsa05033 | 0.66800250 |
| 64 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.63444213 |
| 65 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.62078777 |
| 66 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.59640631 |
| 67 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58607417 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.56782291 |
| 69 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.56605652 |
| 70 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.53845178 |
| 71 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.52942302 |
| 72 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.52859251 |
| 73 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50621630 |
| 74 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.49903807 |
| 75 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47639184 |
| 76 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.45896486 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.44526041 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.43220560 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43135867 |
| 80 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42353534 |
| 81 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.41912867 |
| 82 | Cell cycle_Homo sapiens_hsa04110 | 0.40449297 |
| 83 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.39852986 |
| 84 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.39529000 |
| 85 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.36254310 |
| 86 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.36027257 |
| 87 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.35899502 |
| 88 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.35839129 |
| 89 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34612688 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.32966554 |
| 91 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.32912542 |
| 92 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.30661014 |
| 93 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.28400293 |
| 94 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.28140052 |
| 95 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.27482121 |
| 96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26757530 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.26048497 |
| 98 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24798533 |
| 99 | Morphine addiction_Homo sapiens_hsa05032 | 0.24556755 |
| 100 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.24002407 |

