

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit biogenesis (GO:0042274) | 6.39372322 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 6.22901108 |
| 3 | viral transcription (GO:0019083) | 6.21715699 |
| 4 | translational termination (GO:0006415) | 5.92541619 |
| 5 | maturation of SSU-rRNA (GO:0030490) | 5.36840645 |
| 6 | translational elongation (GO:0006414) | 5.31029386 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.08750904 |
| 8 | formation of translation preinitiation complex (GO:0001731) | 5.00380826 |
| 9 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.96838883 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 4.94788221 |
| 11 | protein targeting to ER (GO:0045047) | 4.90938290 |
| 12 | translational initiation (GO:0006413) | 4.84680357 |
| 13 | viral life cycle (GO:0019058) | 4.80402052 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.67284181 |
| 15 | ribosomal large subunit biogenesis (GO:0042273) | 4.67142693 |
| 16 | protein localization to endoplasmic reticulum (GO:0070972) | 4.64216383 |
| 17 | cellular protein complex disassembly (GO:0043624) | 4.49637965 |
| 18 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.39557679 |
| 19 | protein complex disassembly (GO:0043241) | 4.07050272 |
| 20 | chaperone-mediated protein transport (GO:0072321) | 3.99978899 |
| 21 | translation (GO:0006412) | 3.96739216 |
| 22 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.89247142 |
| 23 | macromolecular complex disassembly (GO:0032984) | 3.83782176 |
| 24 | rRNA modification (GO:0000154) | 3.74902504 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.72608039 |
| 26 | ribosome biogenesis (GO:0042254) | 3.70068160 |
| 27 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.63535600 |
| 28 | rRNA processing (GO:0006364) | 3.62236247 |
| 29 | regulation of mitochondrial translation (GO:0070129) | 3.56891081 |
| 30 | cellular component biogenesis (GO:0044085) | 3.56340296 |
| 31 | transcription from mitochondrial promoter (GO:0006390) | 3.53254616 |
| 32 | base-excision repair, AP site formation (GO:0006285) | 3.52631191 |
| 33 | protein targeting to membrane (GO:0006612) | 3.48335808 |
| 34 | mRNA catabolic process (GO:0006402) | 3.45127673 |
| 35 | rRNA metabolic process (GO:0016072) | 3.44286730 |
| 36 | deoxyribonucleotide catabolic process (GO:0009264) | 3.36319964 |
| 37 | protein targeting to mitochondrion (GO:0006626) | 3.35893132 |
| 38 | RNA catabolic process (GO:0006401) | 3.31483707 |
| 39 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.31067770 |
| 40 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.30064191 |
| 41 | DNA strand elongation (GO:0022616) | 3.27773900 |
| 42 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.25701069 |
| 43 | deoxyribose phosphate catabolic process (GO:0046386) | 3.25488360 |
| 44 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.23298446 |
| 45 | termination of RNA polymerase III transcription (GO:0006386) | 3.23298446 |
| 46 | peptidyl-histidine modification (GO:0018202) | 3.20558693 |
| 47 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.16903513 |
| 48 | proteasome assembly (GO:0043248) | 3.16451179 |
| 49 | spliceosomal snRNP assembly (GO:0000387) | 3.16246310 |
| 50 | establishment of integrated proviral latency (GO:0075713) | 3.14232641 |
| 51 | purine nucleobase biosynthetic process (GO:0009113) | 3.14197085 |
| 52 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.13799830 |
| 53 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.12856033 |
| 54 | establishment of protein localization to mitochondrion (GO:0072655) | 3.12316109 |
| 55 | rRNA methylation (GO:0031167) | 3.12254451 |
| 56 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.12005198 |
| 57 | protein maturation by protein folding (GO:0022417) | 3.11050388 |
| 58 | IMP biosynthetic process (GO:0006188) | 3.05072904 |
| 59 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.03320817 |
| 60 | pentose metabolic process (GO:0019321) | 3.01766034 |
| 61 | ribosome assembly (GO:0042255) | 3.01014110 |
| 62 | DNA replication checkpoint (GO:0000076) | 2.99580859 |
| 63 | pseudouridine synthesis (GO:0001522) | 2.98137304 |
| 64 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.97906029 |
| 65 | establishment of viral latency (GO:0019043) | 2.95747692 |
| 66 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.94270754 |
| 67 | protein localization to mitochondrion (GO:0070585) | 2.93286181 |
| 68 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.92415260 |
| 69 | negative regulation of ligase activity (GO:0051352) | 2.92415260 |
| 70 | ncRNA 3-end processing (GO:0043628) | 2.91798415 |
| 71 | DNA unwinding involved in DNA replication (GO:0006268) | 2.89558228 |
| 72 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.89472173 |
| 73 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.89472173 |
| 74 | nucleobase biosynthetic process (GO:0046112) | 2.88684139 |
| 75 | mitotic metaphase plate congression (GO:0007080) | 2.86344728 |
| 76 | rRNA transcription (GO:0009303) | 2.86298965 |
| 77 | iron-sulfur cluster assembly (GO:0016226) | 2.85367944 |
| 78 | metallo-sulfur cluster assembly (GO:0031163) | 2.85367944 |
| 79 | ncRNA processing (GO:0034470) | 2.85100198 |
| 80 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 2.84881883 |
| 81 | nucleotide salvage (GO:0043173) | 2.84462223 |
| 82 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.84282621 |
| 83 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.82117984 |
| 84 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.81976709 |
| 85 | base-excision repair (GO:0006284) | 2.81619992 |
| 86 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.81311602 |
| 87 | chromatin remodeling at centromere (GO:0031055) | 2.80522827 |
| 88 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.79190469 |
| 89 | CENP-A containing nucleosome assembly (GO:0034080) | 2.78161719 |
| 90 | histone arginine methylation (GO:0034969) | 2.78148843 |
| 91 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.76455179 |
| 92 | negative regulation of RNA splicing (GO:0033119) | 2.76284242 |
| 93 | L-serine metabolic process (GO:0006563) | 2.75661042 |
| 94 | GDP-mannose metabolic process (GO:0019673) | 2.75383525 |
| 95 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.74412496 |
| 96 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.73901898 |
| 97 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.70892179 |
| 98 | mitochondrial fusion (GO:0008053) | 2.67646942 |
| 99 | ncRNA metabolic process (GO:0034660) | 2.66703799 |
| 100 | CTP metabolic process (GO:0046036) | 2.65546614 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.95781337 |
| 2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.84527562 |
| 3 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.52881907 |
| 4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.51150575 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.16643690 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.13947857 |
| 7 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.94553778 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.92636692 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.83740986 |
| 10 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.76300108 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.69753325 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.69455729 |
| 13 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.60473856 |
| 14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.55822200 |
| 15 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.50880750 |
| 16 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.40246451 |
| 17 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.34359163 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.31820627 |
| 19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.26171863 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.21500163 |
| 21 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.16072974 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.13252527 |
| 23 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.11782004 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.05017158 |
| 25 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04388347 |
| 26 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.03698867 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.00698256 |
| 28 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.97637089 |
| 29 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.95964853 |
| 30 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.92224100 |
| 31 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.89630662 |
| 32 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.84693031 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.83233671 |
| 34 | MYC_22102868_ChIP-Seq_BL_Human | 1.81465772 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.80063677 |
| 36 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.77476979 |
| 37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.76861722 |
| 38 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.76720563 |
| 39 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.75361902 |
| 40 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69991488 |
| 41 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.69331377 |
| 42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.69252760 |
| 43 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.65653482 |
| 44 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.64477517 |
| 45 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.56609584 |
| 46 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.56477811 |
| 47 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.54280297 |
| 48 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.51499946 |
| 49 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51210517 |
| 50 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.48220406 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.47261589 |
| 52 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.47207424 |
| 53 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.45469544 |
| 54 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40927194 |
| 55 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38218161 |
| 56 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.37722600 |
| 57 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.36988335 |
| 58 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.30312801 |
| 59 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.29799335 |
| 60 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.29587946 |
| 61 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.28940195 |
| 62 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.28647844 |
| 63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.28278310 |
| 64 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.27649764 |
| 65 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.25423252 |
| 66 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.25029144 |
| 67 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.24099002 |
| 68 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.23405328 |
| 69 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.21354196 |
| 70 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.21248517 |
| 71 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.19875256 |
| 72 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.19467765 |
| 73 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.16203333 |
| 74 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.12959896 |
| 75 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.10995313 |
| 76 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.10593473 |
| 77 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07817808 |
| 78 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.07390527 |
| 79 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.03481874 |
| 80 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.03345146 |
| 81 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.02996568 |
| 82 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.01279771 |
| 83 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.01022625 |
| 84 | MAF_26560356_Chip-Seq_TH2_Human | 1.00715876 |
| 85 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.99732756 |
| 86 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98083187 |
| 87 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.96943232 |
| 88 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.96431136 |
| 89 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.95594950 |
| 90 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.94888212 |
| 91 | P68_20966046_ChIP-Seq_HELA_Human | 0.92923604 |
| 92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.91815922 |
| 93 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.90997416 |
| 94 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.89629411 |
| 95 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.89401609 |
| 96 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.87621425 |
| 97 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.86700645 |
| 98 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.86395059 |
| 99 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.85686016 |
| 100 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.85686016 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.09908488 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.98980140 |
| 3 | MP0008058_abnormal_DNA_repair | 3.49659913 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 3.45953317 |
| 5 | MP0009379_abnormal_foot_pigmentation | 3.35914828 |
| 6 | MP0003111_abnormal_nucleus_morphology | 3.30587660 |
| 7 | MP0003077_abnormal_cell_cycle | 2.94729165 |
| 8 | MP0010094_abnormal_chromosome_stability | 2.82460056 |
| 9 | MP0010030_abnormal_orbit_morphology | 2.73703994 |
| 10 | MP0008932_abnormal_embryonic_tissue | 2.51068722 |
| 11 | MP0009333_abnormal_splenocyte_physiolog | 2.22578733 |
| 12 | MP0008260_abnormal_autophagy | 2.21593360 |
| 13 | MP0003186_abnormal_redox_activity | 2.07032139 |
| 14 | MP0008007_abnormal_cellular_replicative | 1.91057595 |
| 15 | MP0006035_abnormal_mitochondrial_morpho | 1.87986071 |
| 16 | MP0008789_abnormal_olfactory_epithelium | 1.87656849 |
| 17 | MP0001730_embryonic_growth_arrest | 1.85261244 |
| 18 | MP0000490_abnormal_crypts_of | 1.85082196 |
| 19 | MP0003806_abnormal_nucleotide_metabolis | 1.84584170 |
| 20 | MP0003786_premature_aging | 1.81149573 |
| 21 | MP0003718_maternal_effect | 1.75488298 |
| 22 | MP0003123_paternal_imprinting | 1.74204486 |
| 23 | MP0001293_anophthalmia | 1.73731526 |
| 24 | MP0008877_abnormal_DNA_methylation | 1.73253190 |
| 25 | MP0005499_abnormal_olfactory_system | 1.70948410 |
| 26 | MP0005394_taste/olfaction_phenotype | 1.70948410 |
| 27 | MP0000350_abnormal_cell_proliferation | 1.67829827 |
| 28 | MP0006036_abnormal_mitochondrial_physio | 1.65001278 |
| 29 | MP0005058_abnormal_lysosome_morphology | 1.59554230 |
| 30 | MP0002254_reproductive_system_inflammat | 1.58278001 |
| 31 | MP0000313_abnormal_cell_death | 1.56735170 |
| 32 | MP0000358_abnormal_cell_content/ | 1.48848088 |
| 33 | MP0005380_embryogenesis_phenotype | 1.48045067 |
| 34 | MP0001672_abnormal_embryogenesis/_devel | 1.48045067 |
| 35 | MP0005501_abnormal_skin_physiology | 1.41558905 |
| 36 | MP0001697_abnormal_embryo_size | 1.40208318 |
| 37 | MP0002080_prenatal_lethality | 1.37803102 |
| 38 | MP0003315_abnormal_perineum_morphology | 1.35800514 |
| 39 | MP0000678_abnormal_parathyroid_gland | 1.34906626 |
| 40 | MP0002210_abnormal_sex_determination | 1.33731190 |
| 41 | MP0002132_abnormal_respiratory_system | 1.30689918 |
| 42 | MP0009053_abnormal_anal_canal | 1.30339874 |
| 43 | MP0003984_embryonic_growth_retardation | 1.29568242 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.28610417 |
| 45 | MP0002163_abnormal_gland_morphology | 1.24575505 |
| 46 | MP0009278_abnormal_bone_marrow | 1.23853133 |
| 47 | MP0002085_abnormal_embryonic_tissue | 1.22461438 |
| 48 | MP0002088_abnormal_embryonic_growth/wei | 1.21549211 |
| 49 | MP0002396_abnormal_hematopoietic_system | 1.21002190 |
| 50 | MP0003941_abnormal_skin_development | 1.19407497 |
| 51 | MP0009697_abnormal_copulation | 1.18739070 |
| 52 | MP0000049_abnormal_middle_ear | 1.18032296 |
| 53 | MP0002796_impaired_skin_barrier | 1.17965516 |
| 54 | MP0005075_abnormal_melanosome_morpholog | 1.17283129 |
| 55 | MP0008995_early_reproductive_senescence | 1.17041174 |
| 56 | MP0002019_abnormal_tumor_incidence | 1.14023513 |
| 57 | MP0001145_abnormal_male_reproductive | 1.13555742 |
| 58 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12196916 |
| 59 | MP0002160_abnormal_reproductive_system | 1.11398052 |
| 60 | MP0005451_abnormal_body_composition | 1.09143605 |
| 61 | MP0001929_abnormal_gametogenesis | 1.07136377 |
| 62 | MP0005083_abnormal_biliary_tract | 1.06898090 |
| 63 | MP0000750_abnormal_muscle_regeneration | 1.06509421 |
| 64 | MP0004185_abnormal_adipocyte_glucose | 1.01937837 |
| 65 | MP0008057_abnormal_DNA_replication | 0.99798802 |
| 66 | MP0009672_abnormal_birth_weight | 0.98340024 |
| 67 | MP0000653_abnormal_sex_gland | 0.96395861 |
| 68 | MP0001764_abnormal_homeostasis | 0.95760994 |
| 69 | MP0005377_hearing/vestibular/ear_phenot | 0.93837531 |
| 70 | MP0003878_abnormal_ear_physiology | 0.93837531 |
| 71 | MP0000703_abnormal_thymus_morphology | 0.92689957 |
| 72 | MP0002653_abnormal_ependyma_morphology | 0.92251411 |
| 73 | MP0002249_abnormal_larynx_morphology | 0.91907052 |
| 74 | MP0002398_abnormal_bone_marrow | 0.90859293 |
| 75 | MP0002722_abnormal_immune_system | 0.88739011 |
| 76 | MP0000689_abnormal_spleen_morphology | 0.86863664 |
| 77 | MP0002938_white_spotting | 0.86255828 |
| 78 | MP0002084_abnormal_developmental_patter | 0.85884363 |
| 79 | MP0001849_ear_inflammation | 0.84145199 |
| 80 | MP0002429_abnormal_blood_cell | 0.84128244 |
| 81 | MP0009840_abnormal_foam_cell | 0.82463544 |
| 82 | MP0001119_abnormal_female_reproductive | 0.78256963 |
| 83 | MP0005670_abnormal_white_adipose | 0.77683175 |
| 84 | MP0002086_abnormal_extraembryonic_tissu | 0.77569446 |
| 85 | MP0001545_abnormal_hematopoietic_system | 0.77186720 |
| 86 | MP0005397_hematopoietic_system_phenotyp | 0.77186720 |
| 87 | MP0002111_abnormal_tail_morphology | 0.73752539 |
| 88 | MP0005384_cellular_phenotype | 0.72300734 |
| 89 | MP0002697_abnormal_eye_size | 0.70934589 |
| 90 | MP0004197_abnormal_fetal_growth/weight/ | 0.69571381 |
| 91 | MP0005367_renal/urinary_system_phenotyp | 0.68626501 |
| 92 | MP0000516_abnormal_urinary_system | 0.68626501 |
| 93 | MP0001188_hyperpigmentation | 0.68614191 |
| 94 | MP0002092_abnormal_eye_morphology | 0.68493814 |
| 95 | MP0010307_abnormal_tumor_latency | 0.68263853 |
| 96 | MP0005084_abnormal_gallbladder_morpholo | 0.65877493 |
| 97 | MP0003698_abnormal_male_reproductive | 0.65479127 |
| 98 | MP0000716_abnormal_immune_system | 0.64947022 |
| 99 | MP0004264_abnormal_extraembryonic_tissu | 0.64754965 |
| 100 | MP0001529_abnormal_vocalization | 0.63743018 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.41751873 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.52805439 |
| 3 | Abnormal number of erythroid precursors (HP:0012131) | 4.25830466 |
| 4 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 4.24907870 |
| 5 | Microvesicular hepatic steatosis (HP:0001414) | 4.08303393 |
| 6 | Macrocytic anemia (HP:0001972) | 3.45185298 |
| 7 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.35312101 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.22675400 |
| 9 | Multiple enchondromatosis (HP:0005701) | 3.17380302 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.15724493 |
| 11 | Microretrognathia (HP:0000308) | 3.14215610 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.12288881 |
| 13 | Pallor (HP:0000980) | 3.11029313 |
| 14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.06352261 |
| 15 | Increased CSF lactate (HP:0002490) | 3.05584330 |
| 16 | Respiratory difficulties (HP:0002880) | 2.95946296 |
| 17 | Hepatocellular necrosis (HP:0001404) | 2.93709763 |
| 18 | Acute encephalopathy (HP:0006846) | 2.93657026 |
| 19 | Progressive muscle weakness (HP:0003323) | 2.91391277 |
| 20 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.89469785 |
| 21 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.89469785 |
| 22 | Increased intramyocellular lipid droplets (HP:0012240) | 2.89237294 |
| 23 | Aplastic anemia (HP:0001915) | 2.80594705 |
| 24 | Progressive external ophthalmoplegia (HP:0000590) | 2.76993615 |
| 25 | Lipid accumulation in hepatocytes (HP:0006561) | 2.73680774 |
| 26 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.72087285 |
| 27 | Type I transferrin isoform profile (HP:0003642) | 2.68251625 |
| 28 | Cleft eyelid (HP:0000625) | 2.65379967 |
| 29 | Increased serum lactate (HP:0002151) | 2.64813514 |
| 30 | Horseshoe kidney (HP:0000085) | 2.63516541 |
| 31 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.60885819 |
| 32 | Single umbilical artery (HP:0001195) | 2.60885819 |
| 33 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.60885819 |
| 34 | Testicular atrophy (HP:0000029) | 2.60282292 |
| 35 | Broad distal phalanx of finger (HP:0009836) | 2.55678173 |
| 36 | Increased muscle lipid content (HP:0009058) | 2.54539520 |
| 37 | Reduced antithrombin III activity (HP:0001976) | 2.51834826 |
| 38 | Facial cleft (HP:0002006) | 2.51412623 |
| 39 | Hepatic necrosis (HP:0002605) | 2.49139471 |
| 40 | Lactic acidosis (HP:0003128) | 2.44985597 |
| 41 | Colon cancer (HP:0003003) | 2.40338288 |
| 42 | Exercise intolerance (HP:0003546) | 2.36577739 |
| 43 | Renal Fanconi syndrome (HP:0001994) | 2.35303644 |
| 44 | Abnormality of reticulocytes (HP:0004312) | 2.32183871 |
| 45 | Vaginal fistula (HP:0004320) | 2.30913875 |
| 46 | Thrombocytosis (HP:0001894) | 2.30429877 |
| 47 | Absent thumb (HP:0009777) | 2.30062660 |
| 48 | Trismus (HP:0000211) | 2.27897701 |
| 49 | Poikiloderma (HP:0001029) | 2.27691644 |
| 50 | Ragged-red muscle fibers (HP:0003200) | 2.26923320 |
| 51 | Cerebral hypomyelination (HP:0006808) | 2.21741997 |
| 52 | Progressive macrocephaly (HP:0004481) | 2.19981086 |
| 53 | Premature ovarian failure (HP:0008209) | 2.19640606 |
| 54 | Short middle phalanx of the 5th finger (HP:0004220) | 2.19352122 |
| 55 | Abnormality of the umbilical cord (HP:0010881) | 2.18089462 |
| 56 | Cholecystitis (HP:0001082) | 2.17627662 |
| 57 | Abnormal gallbladder physiology (HP:0012438) | 2.17627662 |
| 58 | Abnormal lung lobation (HP:0002101) | 2.16958691 |
| 59 | Facial hemangioma (HP:0000329) | 2.16182783 |
| 60 | Rectovaginal fistula (HP:0000143) | 2.16115314 |
| 61 | Rectal fistula (HP:0100590) | 2.16115314 |
| 62 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.13510892 |
| 63 | Abnormal protein glycosylation (HP:0012346) | 2.11772435 |
| 64 | Abnormal glycosylation (HP:0012345) | 2.11772435 |
| 65 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.11772435 |
| 66 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.11772435 |
| 67 | Triphalangeal thumb (HP:0001199) | 2.10705498 |
| 68 | Birth length less than 3rd percentile (HP:0003561) | 2.08347978 |
| 69 | Carpal bone hypoplasia (HP:0001498) | 2.06553583 |
| 70 | Cerebral edema (HP:0002181) | 2.05951316 |
| 71 | 3-Methylglutaconic aciduria (HP:0003535) | 1.99129348 |
| 72 | Rough bone trabeculation (HP:0100670) | 1.97738495 |
| 73 | Squamous cell carcinoma (HP:0002860) | 1.96237941 |
| 74 | Absent radius (HP:0003974) | 1.91649823 |
| 75 | Stenosis of the external auditory canal (HP:0000402) | 1.90082650 |
| 76 | Abnormality of the preputium (HP:0100587) | 1.89088339 |
| 77 | Deep palmar crease (HP:0006191) | 1.88903902 |
| 78 | Chromsome breakage (HP:0040012) | 1.88608071 |
| 79 | Agammaglobulinemia (HP:0004432) | 1.87946944 |
| 80 | Ectopic kidney (HP:0000086) | 1.81007591 |
| 81 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.80136188 |
| 82 | Patent foramen ovale (HP:0001655) | 1.79407781 |
| 83 | Intestinal fistula (HP:0100819) | 1.77998884 |
| 84 | Capillary hemangiomas (HP:0005306) | 1.73680020 |
| 85 | Death in infancy (HP:0001522) | 1.73062156 |
| 86 | Pancytopenia (HP:0001876) | 1.72598555 |
| 87 | Basal cell carcinoma (HP:0002671) | 1.72538537 |
| 88 | Absent forearm bone (HP:0003953) | 1.72146122 |
| 89 | Aplasia involving forearm bones (HP:0009822) | 1.72146122 |
| 90 | Meckel diverticulum (HP:0002245) | 1.71720529 |
| 91 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.71165807 |
| 92 | Exertional dyspnea (HP:0002875) | 1.69092878 |
| 93 | Hyperglycinemia (HP:0002154) | 1.68098190 |
| 94 | Petechiae (HP:0000967) | 1.67656159 |
| 95 | Hypoplastic pelvis (HP:0008839) | 1.65885654 |
| 96 | Oligodactyly (HP:0012165) | 1.64674801 |
| 97 | Partial duplication of thumb phalanx (HP:0009944) | 1.64473973 |
| 98 | Choanal stenosis (HP:0000452) | 1.62941453 |
| 99 | Upper motor neuron abnormality (HP:0002127) | 1.61944543 |
| 100 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.61012755 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME2 | 5.39336028 |
| 2 | CDK19 | 4.27410339 |
| 3 | BUB1 | 4.19669194 |
| 4 | STK16 | 3.94244303 |
| 5 | VRK2 | 3.75137856 |
| 6 | TESK2 | 2.60844195 |
| 7 | PBK | 2.54876541 |
| 8 | CDC7 | 2.41520738 |
| 9 | SMG1 | 2.20135047 |
| 10 | ARAF | 2.11338845 |
| 11 | SRPK1 | 2.06238741 |
| 12 | BCKDK | 1.97059342 |
| 13 | PIM2 | 1.83152857 |
| 14 | PASK | 1.74861194 |
| 15 | BRAF | 1.59148319 |
| 16 | DYRK3 | 1.52252413 |
| 17 | TAOK2 | 1.51892238 |
| 18 | TTK | 1.48422735 |
| 19 | LRRK2 | 1.43737662 |
| 20 | PDK2 | 1.37098993 |
| 21 | PRPF4B | 1.31188693 |
| 22 | NUAK1 | 1.27326517 |
| 23 | AURKA | 1.26200374 |
| 24 | IRAK3 | 1.24847897 |
| 25 | ERN1 | 1.24840451 |
| 26 | CHEK2 | 1.24721461 |
| 27 | CDK7 | 1.23977716 |
| 28 | PLK4 | 1.23268449 |
| 29 | VRK1 | 1.21647694 |
| 30 | MAP4K1 | 1.20941019 |
| 31 | MAP3K8 | 1.19343005 |
| 32 | PLK1 | 1.18734656 |
| 33 | MAP2K3 | 1.14264741 |
| 34 | BMX | 1.12936383 |
| 35 | TAF1 | 1.12686788 |
| 36 | TRIM28 | 1.12223012 |
| 37 | MAP3K10 | 1.08279862 |
| 38 | ATR | 0.96554148 |
| 39 | STK4 | 0.94537415 |
| 40 | NME1 | 0.87745150 |
| 41 | AURKB | 0.87505762 |
| 42 | MAP3K11 | 0.87369006 |
| 43 | CDK4 | 0.83620899 |
| 44 | KDR | 0.82068620 |
| 45 | CHEK1 | 0.80727238 |
| 46 | PAK4 | 0.79328747 |
| 47 | NEK2 | 0.78796073 |
| 48 | MST4 | 0.77953259 |
| 49 | PAK1 | 0.77080112 |
| 50 | DYRK2 | 0.76310642 |
| 51 | RPS6KB2 | 0.76307093 |
| 52 | ABL2 | 0.75451479 |
| 53 | ZAK | 0.74738882 |
| 54 | ILK | 0.73826393 |
| 55 | TESK1 | 0.73028186 |
| 56 | PRKCI | 0.72478356 |
| 57 | BRSK1 | 0.72027045 |
| 58 | FLT3 | 0.70675218 |
| 59 | NEK1 | 0.68782581 |
| 60 | MUSK | 0.68328808 |
| 61 | IRAK4 | 0.65609413 |
| 62 | IKBKB | 0.64796330 |
| 63 | PLK3 | 0.63943535 |
| 64 | PIM1 | 0.62971765 |
| 65 | RAF1 | 0.61475877 |
| 66 | GRK6 | 0.60425024 |
| 67 | CSNK2A2 | 0.60163617 |
| 68 | RPS6KA4 | 0.58844109 |
| 69 | CSNK2A1 | 0.57731871 |
| 70 | DAPK3 | 0.56780937 |
| 71 | RPS6KA5 | 0.56653847 |
| 72 | STK10 | 0.55924650 |
| 73 | TNK2 | 0.55680312 |
| 74 | TRIB3 | 0.50685093 |
| 75 | MATK | 0.50626584 |
| 76 | DAPK1 | 0.49656924 |
| 77 | SIK3 | 0.49293839 |
| 78 | CLK1 | 0.48526113 |
| 79 | IRAK2 | 0.48348565 |
| 80 | SIK1 | 0.47720695 |
| 81 | WEE1 | 0.47689352 |
| 82 | RPS6KC1 | 0.45343868 |
| 83 | RPS6KL1 | 0.45343868 |
| 84 | CDK2 | 0.44901946 |
| 85 | MKNK1 | 0.44457264 |
| 86 | CDK8 | 0.42547935 |
| 87 | EIF2AK2 | 0.41872972 |
| 88 | CSF1R | 0.38342611 |
| 89 | MAP3K3 | 0.37173377 |
| 90 | RPS6KA1 | 0.36768906 |
| 91 | TAOK1 | 0.36566644 |
| 92 | AKT2 | 0.36280469 |
| 93 | ATM | 0.34548548 |
| 94 | MAP2K2 | 0.34234037 |
| 95 | CDK11A | 0.33487539 |
| 96 | TBK1 | 0.32909278 |
| 97 | MARK3 | 0.30238972 |
| 98 | RPS6KA6 | 0.30159027 |
| 99 | CDK1 | 0.30074848 |
| 100 | EIF2AK3 | 0.29210091 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.67582802 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 3.80844984 |
| 3 | Base excision repair_Homo sapiens_hsa03410 | 3.36330548 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.16333823 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.10470913 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 3.03720654 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.89446325 |
| 8 | Spliceosome_Homo sapiens_hsa03040 | 2.53129571 |
| 9 | Sulfur relay system_Homo sapiens_hsa04122 | 2.39791528 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 2.33383684 |
| 11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.28193223 |
| 12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.18233904 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 2.17777287 |
| 14 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.07359693 |
| 15 | Parkinsons disease_Homo sapiens_hsa05012 | 2.06064526 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.79238945 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.74420817 |
| 18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.70814837 |
| 19 | Cell cycle_Homo sapiens_hsa04110 | 1.67656225 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.58014131 |
| 21 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.56951862 |
| 22 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.51107964 |
| 23 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.49472380 |
| 24 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.48708592 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.48461672 |
| 26 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.39551566 |
| 27 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.38435929 |
| 28 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.34896874 |
| 29 | Basal transcription factors_Homo sapiens_hsa03022 | 1.29020799 |
| 30 | Purine metabolism_Homo sapiens_hsa00230 | 1.23486659 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.23467198 |
| 32 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.19177088 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.18631065 |
| 34 | Carbon metabolism_Homo sapiens_hsa01200 | 1.18009026 |
| 35 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.17953353 |
| 36 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.11616098 |
| 37 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.11361957 |
| 38 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.10348291 |
| 39 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.09065093 |
| 40 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.00319334 |
| 41 | Alzheimers disease_Homo sapiens_hsa05010 | 0.93594656 |
| 42 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.92107798 |
| 43 | Galactose metabolism_Homo sapiens_hsa00052 | 0.89544627 |
| 44 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.89457217 |
| 45 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.88370566 |
| 46 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.84644413 |
| 47 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84614557 |
| 48 | Protein export_Homo sapiens_hsa03060 | 0.83451087 |
| 49 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.83376108 |
| 50 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.81170710 |
| 51 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.79973318 |
| 52 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.77864233 |
| 53 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.73811741 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70771360 |
| 55 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67042870 |
| 56 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.65644209 |
| 57 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.63668236 |
| 58 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.62332051 |
| 59 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.60706744 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60656531 |
| 61 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.56697267 |
| 62 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52264937 |
| 63 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.50310559 |
| 64 | Shigellosis_Homo sapiens_hsa05131 | 0.49676197 |
| 65 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49255385 |
| 66 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.45952571 |
| 67 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.45151632 |
| 68 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.43585695 |
| 69 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.43100735 |
| 70 | Bladder cancer_Homo sapiens_hsa05219 | 0.39434370 |
| 71 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.39100340 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.38897344 |
| 73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.37118951 |
| 74 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.35961032 |
| 75 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.34255389 |
| 76 | Thyroid cancer_Homo sapiens_hsa05216 | 0.33644915 |
| 77 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.32680956 |
| 78 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.31499641 |
| 79 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.28662396 |
| 80 | Colorectal cancer_Homo sapiens_hsa05210 | 0.28323937 |
| 81 | Other glycan degradation_Homo sapiens_hsa00511 | 0.27634171 |
| 82 | Apoptosis_Homo sapiens_hsa04210 | 0.26686004 |
| 83 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.24813433 |
| 84 | Legionellosis_Homo sapiens_hsa05134 | 0.24646206 |
| 85 | Asthma_Homo sapiens_hsa05310 | 0.21569491 |
| 86 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.21173069 |
| 87 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.20642260 |
| 88 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.20488237 |
| 89 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.19001178 |
| 90 | Hepatitis B_Homo sapiens_hsa05161 | 0.17795969 |
| 91 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.17258139 |
| 92 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.17116623 |
| 93 | Viral myocarditis_Homo sapiens_hsa05416 | 0.15979757 |
| 94 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.15662739 |
| 95 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.15073771 |
| 96 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.14747897 |
| 97 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.11640989 |
| 98 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.11563796 |
| 99 | Allograft rejection_Homo sapiens_hsa05330 | 0.10716219 |
| 100 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.10336849 |

