

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 8.69147111 |
| 2 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 7.99440181 |
| 3 | negative regulation of metanephros development (GO:0072217) | 7.86031294 |
| 4 | iron coordination entity transport (GO:1901678) | 7.27348257 |
| 5 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 6.76947878 |
| 6 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 6.76947878 |
| 7 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 5.57808787 |
| 8 | regulation of mitotic spindle checkpoint (GO:1903504) | 5.57808787 |
| 9 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 5.35307260 |
| 10 | regulation of vitamin D biosynthetic process (GO:0060556) | 4.91581985 |
| 11 | regulation of podosome assembly (GO:0071801) | 4.89613774 |
| 12 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 4.75494714 |
| 13 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 4.73379948 |
| 14 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.67189355 |
| 15 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.50105320 |
| 16 | regulation of gene silencing by miRNA (GO:0060964) | 4.50105320 |
| 17 | regulation of gene silencing by RNA (GO:0060966) | 4.50105320 |
| 18 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.43949674 |
| 19 | defense response to protozoan (GO:0042832) | 4.40369083 |
| 20 | regulation of gastrulation (GO:0010470) | 4.38297397 |
| 21 | presynaptic membrane assembly (GO:0097105) | 4.31040498 |
| 22 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 4.17452130 |
| 23 | magnesium ion transport (GO:0015693) | 4.07776310 |
| 24 | L-serine metabolic process (GO:0006563) | 4.07292670 |
| 25 | negative regulation of kidney development (GO:0090185) | 4.07063215 |
| 26 | regulation of chemokine biosynthetic process (GO:0045073) | 4.02891433 |
| 27 | regulation of vitamin metabolic process (GO:0030656) | 3.98426648 |
| 28 | regulation of nephron tubule epithelial cell differentiation (GO:0072182) | 3.95446163 |
| 29 | vocalization behavior (GO:0071625) | 3.94130454 |
| 30 | anterior/posterior axis specification, embryo (GO:0008595) | 3.90911333 |
| 31 | response to protozoan (GO:0001562) | 3.82233189 |
| 32 | protein K6-linked ubiquitination (GO:0085020) | 3.75398321 |
| 33 | organelle disassembly (GO:1903008) | 3.72073987 |
| 34 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.65808192 |
| 35 | regulation of epithelial cell differentiation involved in kidney development (GO:2000696) | 3.60268558 |
| 36 | platelet dense granule organization (GO:0060155) | 3.60055605 |
| 37 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.58723591 |
| 38 | serine family amino acid biosynthetic process (GO:0009070) | 3.57594718 |
| 39 | ovulation from ovarian follicle (GO:0001542) | 3.55131045 |
| 40 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.51418186 |
| 41 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.46696478 |
| 42 | otic vesicle formation (GO:0030916) | 3.46642026 |
| 43 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.44255607 |
| 44 | leukocyte apoptotic process (GO:0071887) | 3.43941244 |
| 45 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 3.37531356 |
| 46 | regulation of metanephros development (GO:0072215) | 3.35707331 |
| 47 | mitotic metaphase plate congression (GO:0007080) | 3.33400043 |
| 48 | regulation of cell fate specification (GO:0042659) | 3.32596379 |
| 49 | neuromuscular process controlling posture (GO:0050884) | 3.30571297 |
| 50 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.29784193 |
| 51 | presynaptic membrane organization (GO:0097090) | 3.28670921 |
| 52 | folic acid metabolic process (GO:0046655) | 3.27746020 |
| 53 | regulation of collateral sprouting (GO:0048670) | 3.26634468 |
| 54 | glycine metabolic process (GO:0006544) | 3.19388915 |
| 55 | negative regulation of neurological system process (GO:0031645) | 3.18975130 |
| 56 | positive regulation of muscle cell apoptotic process (GO:0010661) | 3.18543549 |
| 57 | zinc ion transmembrane transport (GO:0071577) | 3.18078002 |
| 58 | intra-S DNA damage checkpoint (GO:0031573) | 3.17936638 |
| 59 | negative regulation of interleukin-17 production (GO:0032700) | 3.17700155 |
| 60 | protein import into nucleus, translocation (GO:0000060) | 3.16344240 |
| 61 | positive regulation of isotype switching (GO:0045830) | 3.13725656 |
| 62 | DNA replication checkpoint (GO:0000076) | 3.13454804 |
| 63 | metaphase plate congression (GO:0051310) | 3.12712003 |
| 64 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.12248673 |
| 65 | regulation of cell fate commitment (GO:0010453) | 3.10636261 |
| 66 | regulation of regulatory T cell differentiation (GO:0045589) | 3.06156323 |
| 67 | organ growth (GO:0035265) | 3.05681839 |
| 68 | protein localization to kinetochore (GO:0034501) | 3.05583098 |
| 69 | regulation of spindle checkpoint (GO:0090231) | 3.03885072 |
| 70 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.01092740 |
| 71 | positive regulation of steroid biosynthetic process (GO:0010893) | 3.00947852 |
| 72 | male meiosis (GO:0007140) | 2.93654546 |
| 73 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.89511689 |
| 74 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 2.89489744 |
| 75 | ATP synthesis coupled proton transport (GO:0015986) | 2.89035458 |
| 76 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.89035458 |
| 77 | regulation of stem cell maintenance (GO:2000036) | 2.88514763 |
| 78 | cell-cell junction maintenance (GO:0045217) | 2.88238726 |
| 79 | tetrahydrofolate metabolic process (GO:0046653) | 2.86096803 |
| 80 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 2.81991918 |
| 81 | positive regulation of osteoclast differentiation (GO:0045672) | 2.81955600 |
| 82 | serine family amino acid catabolic process (GO:0009071) | 2.81514158 |
| 83 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.81143324 |
| 84 | purine nucleobase biosynthetic process (GO:0009113) | 2.75818956 |
| 85 | maturation of 5.8S rRNA (GO:0000460) | 2.72237140 |
| 86 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 2.71128193 |
| 87 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.69752012 |
| 88 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.69752012 |
| 89 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.69752012 |
| 90 | positive regulation of DNA recombination (GO:0045911) | 2.67348410 |
| 91 | negative regulation of cell fate specification (GO:0009996) | 2.66730225 |
| 92 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.66517189 |
| 93 | establishment of endothelial barrier (GO:0061028) | 2.66384568 |
| 94 | negative regulation of cardiac muscle tissue development (GO:0055026) | 2.64429892 |
| 95 | T cell differentiation involved in immune response (GO:0002292) | 2.64101881 |
| 96 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.64101881 |
| 97 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.64101881 |
| 98 | regulation of smooth muscle cell apoptotic process (GO:0034391) | 2.63153623 |
| 99 | ncRNA catabolic process (GO:0034661) | 2.62761281 |
| 100 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 2.62495699 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 5.65172177 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.03307855 |
| 3 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.88683817 |
| 4 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.72637878 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.23378580 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.97074941 |
| 7 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.91488471 |
| 8 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.79622241 |
| 9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.79094334 |
| 10 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.57635945 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.53709504 |
| 12 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.51783105 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.49177974 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.42681721 |
| 15 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.34943685 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.30688070 |
| 17 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 2.16553395 |
| 18 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.10231915 |
| 19 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.93850908 |
| 20 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.93779105 |
| 21 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.89125097 |
| 22 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.87998953 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.85579483 |
| 24 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.84267960 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.83742787 |
| 26 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.82125324 |
| 27 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.79323957 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.78036382 |
| 29 | GATA1_22025678_ChIP-Seq_K562_Human | 1.72843793 |
| 30 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.72623360 |
| 31 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.65328917 |
| 32 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.62738230 |
| 33 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.60602460 |
| 34 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.56868211 |
| 35 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.55829294 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.50427838 |
| 37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.46408512 |
| 38 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45987757 |
| 39 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.45871246 |
| 40 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.45871246 |
| 41 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.45871246 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.44376654 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.41064224 |
| 44 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.39953103 |
| 45 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.38489705 |
| 46 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.38231384 |
| 47 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.35740304 |
| 48 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.33941531 |
| 49 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.26507246 |
| 50 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.23751766 |
| 51 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.22447354 |
| 52 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.22329512 |
| 53 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21998549 |
| 54 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.21827040 |
| 55 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.21371737 |
| 56 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.20897443 |
| 57 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.20878296 |
| 58 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.17435944 |
| 59 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.15499018 |
| 60 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.13760715 |
| 61 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.13201150 |
| 62 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.12353081 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.10521400 |
| 64 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.10113404 |
| 65 | P300_19829295_ChIP-Seq_ESCs_Human | 1.08657028 |
| 66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.06644493 |
| 67 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.04613095 |
| 68 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.04418298 |
| 69 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.03790909 |
| 70 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.93855087 |
| 71 | TP53_16413492_ChIP-PET_HCT116_Human | 0.93129517 |
| 72 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.92932814 |
| 73 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92132334 |
| 74 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.91248747 |
| 75 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.90595742 |
| 76 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.90315216 |
| 77 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.89964168 |
| 78 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.89764351 |
| 79 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.89001365 |
| 80 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.88922177 |
| 81 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.87365779 |
| 82 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.85437888 |
| 83 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.84692248 |
| 84 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.84002951 |
| 85 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.83017112 |
| 86 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.82845014 |
| 87 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.82260903 |
| 88 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.82000507 |
| 89 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.81690831 |
| 90 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.81018243 |
| 91 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.80947339 |
| 92 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.80594283 |
| 93 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.79614717 |
| 94 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.79454415 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.79064298 |
| 96 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.77283892 |
| 97 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.77283892 |
| 98 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.75492660 |
| 99 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.75126724 |
| 100 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.74966084 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003941_abnormal_skin_development | 5.53420297 |
| 2 | MP0001873_stomach_inflammation | 4.76994323 |
| 3 | MP0002254_reproductive_system_inflammat | 4.52129267 |
| 4 | MP0010307_abnormal_tumor_latency | 3.53377765 |
| 5 | MP0004019_abnormal_vitamin_homeostasis | 2.99834780 |
| 6 | MP0004782_abnormal_surfactant_physiolog | 2.82771355 |
| 7 | MP0005503_abnormal_tendon_morphology | 2.73351482 |
| 8 | MP0001881_abnormal_mammary_gland | 2.64107160 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.52887847 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.52133135 |
| 11 | MP0009333_abnormal_splenocyte_physiolog | 2.38676401 |
| 12 | MP0003718_maternal_effect | 2.32319910 |
| 13 | MP0000579_abnormal_nail_morphology | 2.31689507 |
| 14 | MP0003646_muscle_fatigue | 2.28688841 |
| 15 | MP0006292_abnormal_olfactory_placode | 2.26936023 |
| 16 | MP0003011_delayed_dark_adaptation | 2.26782279 |
| 17 | MP0003329_amyloid_beta_deposits | 2.25050657 |
| 18 | MP0008877_abnormal_DNA_methylation | 2.17659222 |
| 19 | MP0008058_abnormal_DNA_repair | 2.11344858 |
| 20 | MP0003950_abnormal_plasma_membrane | 2.06897741 |
| 21 | MP0003183_abnormal_peptide_metabolism | 2.02943001 |
| 22 | MP0000467_abnormal_esophagus_morphology | 2.00340867 |
| 23 | MP0000569_abnormal_digit_pigmentation | 1.96487169 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.95854257 |
| 25 | MP0001188_hyperpigmentation | 1.86818373 |
| 26 | MP0002928_abnormal_bile_duct | 1.76358671 |
| 27 | MP0003195_calcinosis | 1.75455277 |
| 28 | MP0010094_abnormal_chromosome_stability | 1.72715075 |
| 29 | MP0000049_abnormal_middle_ear | 1.58129448 |
| 30 | MP0003936_abnormal_reproductive_system | 1.56414866 |
| 31 | MP0002405_respiratory_system_inflammati | 1.51366153 |
| 32 | MP0001835_abnormal_antigen_presentation | 1.48901869 |
| 33 | MP0001663_abnormal_digestive_system | 1.46451808 |
| 34 | MP0009785_altered_susceptibility_to | 1.46390057 |
| 35 | MP0003186_abnormal_redox_activity | 1.35441338 |
| 36 | MP0000627_abnormal_mammary_gland | 1.29808071 |
| 37 | MP0002277_abnormal_respiratory_mucosa | 1.25946459 |
| 38 | MP0000762_abnormal_tongue_morphology | 1.22274828 |
| 39 | MP0005332_abnormal_amino_acid | 1.21583817 |
| 40 | MP0000678_abnormal_parathyroid_gland | 1.20495494 |
| 41 | MP0001501_abnormal_sleep_pattern | 1.20436016 |
| 42 | MP0004185_abnormal_adipocyte_glucose | 1.19962509 |
| 43 | MP0004957_abnormal_blastocyst_morpholog | 1.19762934 |
| 44 | MP0003806_abnormal_nucleotide_metabolis | 1.18907934 |
| 45 | MP0000566_synostosis | 1.18877700 |
| 46 | MP0005381_digestive/alimentary_phenotyp | 1.16847677 |
| 47 | MP0000749_muscle_degeneration | 1.13612731 |
| 48 | MP0002796_impaired_skin_barrier | 1.11332285 |
| 49 | MP0001293_anophthalmia | 1.10607991 |
| 50 | MP0005501_abnormal_skin_physiology | 1.08659579 |
| 51 | MP0002111_abnormal_tail_morphology | 1.05039565 |
| 52 | MP0000604_amyloidosis | 1.04083174 |
| 53 | MP0000631_abnormal_neuroendocrine_gland | 1.03358510 |
| 54 | MP0002876_abnormal_thyroid_physiology | 1.03215870 |
| 55 | MP0001958_emphysema | 1.03196429 |
| 56 | MP0003638_abnormal_response/metabolism_ | 1.02555373 |
| 57 | MP0003699_abnormal_female_reproductive | 1.02528854 |
| 58 | MP0002160_abnormal_reproductive_system | 1.02361121 |
| 59 | MP0005671_abnormal_response_to | 1.01691611 |
| 60 | MP0002177_abnormal_outer_ear | 0.97171989 |
| 61 | MP0002909_abnormal_adrenal_gland | 0.96958271 |
| 62 | MP0005551_abnormal_eye_electrophysiolog | 0.93623566 |
| 63 | MP0008872_abnormal_physiological_respon | 0.91142223 |
| 64 | MP0005508_abnormal_skeleton_morphology | 0.85302411 |
| 65 | MP0004272_abnormal_basement_membrane | 0.84712565 |
| 66 | MP0000013_abnormal_adipose_tissue | 0.83879953 |
| 67 | MP0002210_abnormal_sex_determination | 0.83338625 |
| 68 | MP0003937_abnormal_limbs/digits/tail_de | 0.80978322 |
| 69 | MP0008770_decreased_survivor_rate | 0.79776049 |
| 70 | MP0002295_abnormal_pulmonary_circulatio | 0.78341088 |
| 71 | MP0005389_reproductive_system_phenotype | 0.78335811 |
| 72 | MP0002136_abnormal_kidney_physiology | 0.77747938 |
| 73 | MP0001119_abnormal_female_reproductive | 0.76959401 |
| 74 | MP0002933_joint_inflammation | 0.76121986 |
| 75 | MP0003938_abnormal_ear_development | 0.74912005 |
| 76 | MP0010678_abnormal_skin_adnexa | 0.71771050 |
| 77 | MP0002127_abnormal_cardiovascular_syste | 0.71748838 |
| 78 | MP0003119_abnormal_digestive_system | 0.71484638 |
| 79 | MP0005083_abnormal_biliary_tract | 0.71010200 |
| 80 | MP0009780_abnormal_chondrocyte_physiolo | 0.68023637 |
| 81 | MP0003828_pulmonary_edema | 0.67477610 |
| 82 | MP0002697_abnormal_eye_size | 0.65463730 |
| 83 | MP0003943_abnormal_hepatobiliary_system | 0.64881353 |
| 84 | MP0005636_abnormal_mineral_homeostasis | 0.63527836 |
| 85 | MP0000470_abnormal_stomach_morphology | 0.63190656 |
| 86 | MP0000685_abnormal_immune_system | 0.63108946 |
| 87 | MP0001286_abnormal_eye_development | 0.62347737 |
| 88 | MP0002108_abnormal_muscle_morphology | 0.60972678 |
| 89 | MP0005174_abnormal_tail_pigmentation | 0.60867543 |
| 90 | MP0001299_abnormal_eye_distance/ | 0.60556880 |
| 91 | MP0003077_abnormal_cell_cycle | 0.59974859 |
| 92 | MP0000383_abnormal_hair_follicle | 0.58494651 |
| 93 | MP0003448_altered_tumor_morphology | 0.58325721 |
| 94 | MP0004197_abnormal_fetal_growth/weight/ | 0.58316830 |
| 95 | MP0003385_abnormal_body_wall | 0.58088080 |
| 96 | MP0000681_abnormal_thyroid_gland | 0.56991600 |
| 97 | MP0000639_abnormal_adrenal_gland | 0.56360042 |
| 98 | MP0001986_abnormal_taste_sensitivity | 0.55701689 |
| 99 | MP0010234_abnormal_vibrissa_follicle | 0.55160973 |
| 100 | MP0005319_abnormal_enzyme/_coenzyme | 0.54094640 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hypomagnesemia (HP:0002917) | 5.94851589 |
| 2 | Tetany (HP:0001281) | 5.86512763 |
| 3 | Abnormality of magnesium homeostasis (HP:0004921) | 4.92418487 |
| 4 | Abnormality of homocysteine metabolism (HP:0010919) | 4.50209193 |
| 5 | Homocystinuria (HP:0002156) | 4.50209193 |
| 6 | Pancreatic islet-cell hyperplasia (HP:0004510) | 4.45016886 |
| 7 | Methylmalonic aciduria (HP:0012120) | 3.89846530 |
| 8 | Abnormal drinking behavior (HP:0030082) | 3.71826280 |
| 9 | Polydipsia (HP:0001959) | 3.71826280 |
| 10 | Hyperglycinuria (HP:0003108) | 3.53910458 |
| 11 | Hyperglycinemia (HP:0002154) | 3.43140020 |
| 12 | Split foot (HP:0001839) | 3.26321619 |
| 13 | Abnormality of the vertebral endplates (HP:0005106) | 3.22017051 |
| 14 | Irregular epiphyses (HP:0010582) | 3.14321075 |
| 15 | Thyroid-stimulating hormone excess (HP:0002925) | 3.12578359 |
| 16 | Hyperuricemia (HP:0002149) | 3.11639303 |
| 17 | Increased purine levels (HP:0004368) | 3.11639303 |
| 18 | Hypoglycemic seizures (HP:0002173) | 3.04030321 |
| 19 | Humeroradial synostosis (HP:0003041) | 2.98767290 |
| 20 | Synostosis involving the elbow (HP:0003938) | 2.98767290 |
| 21 | Increased hepatocellular lipid droplets (HP:0006565) | 2.88983143 |
| 22 | Septo-optic dysplasia (HP:0100842) | 2.87572726 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 2.87570658 |
| 24 | Hypoplasia of the pons (HP:0012110) | 2.83473561 |
| 25 | Abnormality of the pons (HP:0007361) | 2.78567299 |
| 26 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.71608567 |
| 27 | Confusion (HP:0001289) | 2.68173090 |
| 28 | Abnormality of glycine metabolism (HP:0010895) | 2.58150428 |
| 29 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.58150428 |
| 30 | Methylmalonic acidemia (HP:0002912) | 2.57996401 |
| 31 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.56201850 |
| 32 | Stridor (HP:0010307) | 2.54723188 |
| 33 | Esophageal atresia (HP:0002032) | 2.54176221 |
| 34 | Stomach cancer (HP:0012126) | 2.52939438 |
| 35 | Exercise-induced muscle cramps (HP:0003710) | 2.52024233 |
| 36 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.47254773 |
| 37 | Aplasia of the phalanges of the hand (HP:0009802) | 2.47254773 |
| 38 | Aplasia involving bones of the extremities (HP:0009825) | 2.47254773 |
| 39 | Multifactorial inheritance (HP:0001426) | 2.46993261 |
| 40 | Broad metatarsal (HP:0001783) | 2.46504501 |
| 41 | Absent epiphyses (HP:0010577) | 2.46101704 |
| 42 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.46101704 |
| 43 | Polyuria (HP:0000103) | 2.43334188 |
| 44 | Hypoplasia of the radius (HP:0002984) | 2.42971967 |
| 45 | Impulsivity (HP:0100710) | 2.41708159 |
| 46 | Hypothermia (HP:0002045) | 2.41267426 |
| 47 | Exertional dyspnea (HP:0002875) | 2.39135497 |
| 48 | Short hallux (HP:0010109) | 2.35150489 |
| 49 | Anomalous pulmonary venous return (HP:0010772) | 2.34818191 |
| 50 | Abnormal number of erythroid precursors (HP:0012131) | 2.30102498 |
| 51 | Polygenic inheritance (HP:0010982) | 2.29579145 |
| 52 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.29045156 |
| 53 | Abnormality of serum amino acid levels (HP:0003112) | 2.26430661 |
| 54 | Symptomatic seizures (HP:0011145) | 2.26204117 |
| 55 | Bilateral microphthalmos (HP:0007633) | 2.24270348 |
| 56 | Abnormality of chromosome stability (HP:0003220) | 2.23498049 |
| 57 | Meckel diverticulum (HP:0002245) | 2.19470480 |
| 58 | Enlarged epiphyses (HP:0010580) | 2.17452345 |
| 59 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.17239240 |
| 60 | Hypoplastic pelvis (HP:0008839) | 2.16476806 |
| 61 | Abnormality of the ileum (HP:0001549) | 2.14464118 |
| 62 | Diaphragmatic weakness (HP:0009113) | 2.10237884 |
| 63 | Absent septum pellucidum (HP:0001331) | 2.07847248 |
| 64 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.07653200 |
| 65 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.07653200 |
| 66 | Hypoglycemic coma (HP:0001325) | 2.05862031 |
| 67 | Fibular aplasia (HP:0002990) | 2.04222186 |
| 68 | Renal tubular acidosis (HP:0001947) | 2.02911663 |
| 69 | Attenuation of retinal blood vessels (HP:0007843) | 2.02607969 |
| 70 | IgA deficiency (HP:0002720) | 2.01797695 |
| 71 | Acute necrotizing encephalopathy (HP:0006965) | 2.01721610 |
| 72 | Abnormality of the pulmonary veins (HP:0011718) | 1.98784904 |
| 73 | Irregular vertebral endplates (HP:0003301) | 1.97389686 |
| 74 | Hyperlipoproteinemia (HP:0010980) | 1.96911089 |
| 75 | Abnormality of vitamin metabolism (HP:0100508) | 1.95265558 |
| 76 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 1.94608224 |
| 77 | Acute encephalopathy (HP:0006846) | 1.93787126 |
| 78 | Cutaneous finger syndactyly (HP:0010554) | 1.92782139 |
| 79 | Cerebellar dysplasia (HP:0007033) | 1.92614850 |
| 80 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.90368948 |
| 81 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.90169775 |
| 82 | Abnormality of femoral epiphyses (HP:0006499) | 1.90169775 |
| 83 | Flattened epiphyses (HP:0003071) | 1.89665471 |
| 84 | Forearm undergrowth (HP:0009821) | 1.86920823 |
| 85 | Carpal bone hypoplasia (HP:0001498) | 1.86800808 |
| 86 | Mitochondrial inheritance (HP:0001427) | 1.86759848 |
| 87 | Type II lissencephaly (HP:0007260) | 1.86430393 |
| 88 | Abnormal urine output (HP:0012590) | 1.86086779 |
| 89 | Cutaneous syndactyly (HP:0012725) | 1.85785249 |
| 90 | Lethargy (HP:0001254) | 1.85401506 |
| 91 | Abnormality of the labia minora (HP:0012880) | 1.85176108 |
| 92 | Intrahepatic cholestasis (HP:0001406) | 1.83719599 |
| 93 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.83169980 |
| 94 | Dialeptic seizures (HP:0011146) | 1.82741429 |
| 95 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.81156916 |
| 96 | Abnormality of purine metabolism (HP:0004352) | 1.80246450 |
| 97 | Chronic otitis media (HP:0000389) | 1.79264394 |
| 98 | Abnormality of cochlea (HP:0000375) | 1.78877179 |
| 99 | Barrel-shaped chest (HP:0001552) | 1.78502376 |
| 100 | Renal Fanconi syndrome (HP:0001994) | 1.76784293 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME1 | 4.79933752 |
| 2 | PBK | 4.63511906 |
| 3 | TRIB3 | 3.61859048 |
| 4 | BUB1 | 3.40572053 |
| 5 | MAP3K14 | 2.78654450 |
| 6 | MST4 | 2.66911891 |
| 7 | CDK12 | 2.52775743 |
| 8 | BMPR1B | 2.39650769 |
| 9 | TXK | 2.23341877 |
| 10 | FGFR2 | 2.21713683 |
| 11 | MAPK15 | 2.14675525 |
| 12 | CDC7 | 2.09010561 |
| 13 | STK4 | 2.00768677 |
| 14 | TAOK3 | 1.82863062 |
| 15 | MKNK2 | 1.79913707 |
| 16 | TNIK | 1.74981356 |
| 17 | TLK1 | 1.68117184 |
| 18 | PNCK | 1.62142094 |
| 19 | EIF2AK2 | 1.58023314 |
| 20 | WNK3 | 1.55575191 |
| 21 | GRK1 | 1.53500891 |
| 22 | NTRK2 | 1.53412957 |
| 23 | EPHA2 | 1.52912003 |
| 24 | OXSR1 | 1.48259153 |
| 25 | CDK19 | 1.43983492 |
| 26 | FGFR1 | 1.40362169 |
| 27 | NEK1 | 1.33966312 |
| 28 | PKN1 | 1.29930589 |
| 29 | PTK6 | 1.29386059 |
| 30 | TTK | 1.27138562 |
| 31 | PLK1 | 1.22639528 |
| 32 | CLK1 | 1.17179121 |
| 33 | BMX | 1.12702869 |
| 34 | ADRBK2 | 1.09412785 |
| 35 | PLK3 | 1.09221438 |
| 36 | ZAK | 1.08714186 |
| 37 | ILK | 1.06329906 |
| 38 | PAK3 | 1.01343738 |
| 39 | NEK2 | 0.99913552 |
| 40 | ACVR1B | 0.99069629 |
| 41 | FLT3 | 0.95747486 |
| 42 | ERN1 | 0.89499380 |
| 43 | CSNK1A1 | 0.88957631 |
| 44 | EIF2AK3 | 0.86969083 |
| 45 | CDK7 | 0.85113990 |
| 46 | CAMK1 | 0.83799718 |
| 47 | CSF1R | 0.83187077 |
| 48 | MKNK1 | 0.82785047 |
| 49 | AURKB | 0.80468310 |
| 50 | CHUK | 0.77977336 |
| 51 | ATR | 0.77010399 |
| 52 | VRK1 | 0.73215582 |
| 53 | STK3 | 0.70670490 |
| 54 | MAP3K10 | 0.69692775 |
| 55 | CHEK2 | 0.68364937 |
| 56 | PKN2 | 0.67811502 |
| 57 | PRKCE | 0.65489761 |
| 58 | ERBB2 | 0.64996415 |
| 59 | AKT3 | 0.63403006 |
| 60 | IGF1R | 0.62828877 |
| 61 | MAP3K7 | 0.60636563 |
| 62 | BRSK2 | 0.59029814 |
| 63 | MAP3K3 | 0.58915023 |
| 64 | CAMK1G | 0.58086267 |
| 65 | MAP3K9 | 0.58013099 |
| 66 | DMPK | 0.57054729 |
| 67 | IKBKE | 0.55351301 |
| 68 | PINK1 | 0.54611900 |
| 69 | STK11 | 0.54383559 |
| 70 | CSNK1E | 0.52604877 |
| 71 | PRKCG | 0.51006193 |
| 72 | MAPKAPK2 | 0.48655719 |
| 73 | CSNK2A2 | 0.47265067 |
| 74 | ATM | 0.46120360 |
| 75 | TEC | 0.44864213 |
| 76 | PIM1 | 0.43132924 |
| 77 | MYLK | 0.42455882 |
| 78 | CDK3 | 0.41048004 |
| 79 | PRKCQ | 0.40666875 |
| 80 | CSNK2A1 | 0.40538664 |
| 81 | CHEK1 | 0.40075610 |
| 82 | WEE1 | 0.39503518 |
| 83 | INSR | 0.39182514 |
| 84 | GSK3A | 0.39126934 |
| 85 | CSNK1G1 | 0.38063577 |
| 86 | PDK2 | 0.35981905 |
| 87 | PDK1 | 0.34890541 |
| 88 | PRKDC | 0.34126574 |
| 89 | MAP3K4 | 0.33663618 |
| 90 | CAMK2A | 0.32981903 |
| 91 | ERBB4 | 0.32507618 |
| 92 | MET | 0.32222476 |
| 93 | IKBKB | 0.31322991 |
| 94 | CAMK4 | 0.31029822 |
| 95 | TIE1 | 0.31022967 |
| 96 | CSNK1D | 0.30408465 |
| 97 | MAPK14 | 0.29099497 |
| 98 | CSNK1G3 | 0.27612738 |
| 99 | PRKACB | 0.27386236 |
| 100 | CSNK1G2 | 0.26745644 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | One carbon pool by folate_Homo sapiens_hsa00670 | 4.20793863 |
| 2 | Homologous recombination_Homo sapiens_hsa03440 | 4.00407693 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.15968981 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.12863898 |
| 5 | African trypanosomiasis_Homo sapiens_hsa05143 | 2.97483860 |
| 6 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.70005124 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.35850879 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.21692793 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.14121532 |
| 10 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.99049572 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 1.96257971 |
| 12 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.89515941 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.88042987 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.83526467 |
| 15 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.82922288 |
| 16 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.79234556 |
| 17 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.72792241 |
| 18 | Spliceosome_Homo sapiens_hsa03040 | 1.71684423 |
| 19 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.53191827 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.51759862 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.48695756 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.47848617 |
| 23 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.45077504 |
| 24 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.44801245 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.37064770 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.28583128 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.20802095 |
| 28 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.16996689 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.15196546 |
| 30 | Protein export_Homo sapiens_hsa03060 | 1.14677933 |
| 31 | Salivary secretion_Homo sapiens_hsa04970 | 1.14507245 |
| 32 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.12602360 |
| 33 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.12144656 |
| 34 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.12015484 |
| 35 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.10565400 |
| 36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.09702708 |
| 37 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.08891530 |
| 38 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.04557861 |
| 39 | Basal transcription factors_Homo sapiens_hsa03022 | 1.01717733 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 0.99248280 |
| 41 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.97835800 |
| 42 | Tight junction_Homo sapiens_hsa04530 | 0.97131867 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 0.89258079 |
| 44 | Mismatch repair_Homo sapiens_hsa03430 | 0.88352810 |
| 45 | Base excision repair_Homo sapiens_hsa03410 | 0.87533043 |
| 46 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.86348642 |
| 47 | Allograft rejection_Homo sapiens_hsa05330 | 0.84693060 |
| 48 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.83948310 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.83662374 |
| 50 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.79599187 |
| 51 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.78214556 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78134225 |
| 53 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.77171565 |
| 54 | Retinol metabolism_Homo sapiens_hsa00830 | 0.75060560 |
| 55 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.74894822 |
| 56 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.74068210 |
| 57 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.73807273 |
| 58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.73419280 |
| 59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.72591836 |
| 60 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.72373125 |
| 61 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.71847261 |
| 62 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.70282534 |
| 63 | Hepatitis C_Homo sapiens_hsa05160 | 0.66091999 |
| 64 | RNA transport_Homo sapiens_hsa03013 | 0.64884339 |
| 65 | Malaria_Homo sapiens_hsa05144 | 0.64062080 |
| 66 | Amoebiasis_Homo sapiens_hsa05146 | 0.62625206 |
| 67 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.62099112 |
| 68 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.62027512 |
| 69 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.61845690 |
| 70 | DNA replication_Homo sapiens_hsa03030 | 0.61811126 |
| 71 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.61692041 |
| 72 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.59894680 |
| 73 | Taste transduction_Homo sapiens_hsa04742 | 0.59759105 |
| 74 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.59285088 |
| 75 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.57102646 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56789189 |
| 77 | Thyroid cancer_Homo sapiens_hsa05216 | 0.56178506 |
| 78 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.55057321 |
| 79 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.54973070 |
| 80 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.53906161 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51444430 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51390104 |
| 83 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.51307312 |
| 84 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.48021972 |
| 85 | Measles_Homo sapiens_hsa05162 | 0.47442530 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.46758653 |
| 87 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.45969406 |
| 88 | Prostate cancer_Homo sapiens_hsa05215 | 0.44541857 |
| 89 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.44152729 |
| 90 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.42203292 |
| 91 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42071675 |
| 92 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.37297862 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.36047388 |
| 94 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.36046646 |
| 95 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.34201873 |
| 96 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.33941482 |
| 97 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.33732449 |
| 98 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.33287010 |
| 99 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.33024848 |
| 100 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.32545828 |

