ZNF602P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of chromatin binding (GO:0035561)5.24515365
2synapsis (GO:0007129)4.89006069
3resolution of meiotic recombination intermediates (GO:0000712)4.86123580
4ganglion development (GO:0061548)4.74892068
5detection of light stimulus involved in sensory perception (GO:0050962)4.70966186
6detection of light stimulus involved in visual perception (GO:0050908)4.70966186
7protein heterotetramerization (GO:0051290)4.66840519
8male meiosis I (GO:0007141)4.61606693
9mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.53218460
10chromosome organization involved in meiosis (GO:0070192)4.48567086
11synaptonemal complex assembly (GO:0007130)4.37409950
12establishment of mitochondrion localization (GO:0051654)4.30631672
13mitochondrion transport along microtubule (GO:0047497)4.30030478
14establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.30030478
15piRNA metabolic process (GO:0034587)4.11835395
16ATP synthesis coupled proton transport (GO:0015986)4.04518519
17energy coupled proton transport, down electrochemical gradient (GO:0015985)4.04518519
18transmission of nerve impulse (GO:0019226)4.01694744
19pyrimidine nucleobase catabolic process (GO:0006208)4.00252408
20chaperone-mediated protein transport (GO:0072321)3.92552125
21synaptonemal complex organization (GO:0070193)3.78141075
22ectoderm development (GO:0007398)3.76364150
23ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043163.72990122
24dorsal/ventral axis specification (GO:0009950)3.68238159
25detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)3.65779041
26meiosis I (GO:0007127)3.58499253
27gamma-aminobutyric acid transport (GO:0015812)3.53643631
28protein complex biogenesis (GO:0070271)3.52917189
29mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.52710095
30respiratory electron transport chain (GO:0022904)3.50771466
31axonal fasciculation (GO:0007413)3.46445525
32electron transport chain (GO:0022900)3.40533359
33positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.35925682
34axon extension involved in axon guidance (GO:0048846)3.33811506
35neuron projection extension involved in neuron projection guidance (GO:1902284)3.33811506
36synaptic vesicle docking involved in exocytosis (GO:0016081)3.33662307
37positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.32235454
38detection of chemical stimulus involved in sensory perception of taste (GO:0050912)3.31901574
39innervation (GO:0060384)3.30354148
40calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.27582183
41regulation of short-term neuronal synaptic plasticity (GO:0048172)3.22570518
42DNA methylation involved in gamete generation (GO:0043046)3.22372882
43male sex determination (GO:0030238)3.21493547
44mitochondrial respiratory chain complex assembly (GO:0033108)3.20080740
45sensory perception of smell (GO:0007608)3.19867956
46cellular ketone body metabolic process (GO:0046950)3.15964605
47neuron fate determination (GO:0048664)3.14999848
48synaptic vesicle maturation (GO:0016188)3.14383985
49neurofilament cytoskeleton organization (GO:0060052)3.12776400
50cholesterol biosynthetic process (GO:0006695)3.11575151
51inner ear receptor cell development (GO:0060119)3.11446987
52ATP hydrolysis coupled proton transport (GO:0015991)3.09010449
53energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.09010449
54nucleobase catabolic process (GO:0046113)3.07160506
55negative regulation of synaptic transmission, GABAergic (GO:0032229)3.03870474
56regulation of telomere maintenance via telomerase (GO:0032210)3.03463778
57negative regulation of mast cell activation (GO:0033004)3.00618704
58male meiosis (GO:0007140)2.99644849
59establishment of protein localization to mitochondrial membrane (GO:0090151)2.98784631
60regulation of rhodopsin mediated signaling pathway (GO:0022400)2.97759654
61reciprocal DNA recombination (GO:0035825)2.97319407
62reciprocal meiotic recombination (GO:0007131)2.97319407
63ketone body metabolic process (GO:1902224)2.96618560
64organelle disassembly (GO:1903008)2.94118249
65neuron remodeling (GO:0016322)2.90014995
66base-excision repair, AP site formation (GO:0006285)2.89784569
67tachykinin receptor signaling pathway (GO:0007217)2.89113291
68ncRNA 3-end processing (GO:0043628)2.88018127
69mitochondrial respiratory chain complex I assembly (GO:0032981)2.85768901
70NADH dehydrogenase complex assembly (GO:0010257)2.85768901
71mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.85768901
72positive regulation of amino acid transport (GO:0051957)2.84717518
73sterol biosynthetic process (GO:0016126)2.84261124
74negative regulation of nitric-oxide synthase activity (GO:0051001)2.83947571
75embryonic eye morphogenesis (GO:0048048)2.81959473
76respiratory chain complex IV assembly (GO:0008535)2.79398907
77hippocampus development (GO:0021766)2.79383632
78neuron recognition (GO:0008038)2.78503974
79striatum development (GO:0021756)2.75985026
80DNA synthesis involved in DNA repair (GO:0000731)2.75717741
81negative regulation of axon extension involved in axon guidance (GO:0048843)2.75679738
82hydrogen ion transmembrane transport (GO:1902600)2.75422753
83S-adenosylmethionine metabolic process (GO:0046500)2.75410761
84axonemal dynein complex assembly (GO:0070286)2.74165485
85protein neddylation (GO:0045116)2.71069630
86establishment of nucleus localization (GO:0040023)2.70202253
87rhodopsin mediated signaling pathway (GO:0016056)2.69727251
88meiotic nuclear division (GO:0007126)2.68579294
89meiotic cell cycle process (GO:1903046)2.67080682
90regulation of potassium ion transmembrane transporter activity (GO:1901016)2.65820792
91water-soluble vitamin biosynthetic process (GO:0042364)2.64513197
92peptidyl-cysteine modification (GO:0018198)2.63496781
93positive regulation of vesicle fusion (GO:0031340)2.62114174
94substrate-independent telencephalic tangential migration (GO:0021826)2.61789245
95substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.61789245
96preassembly of GPI anchor in ER membrane (GO:0016254)2.58964564
97negative regulation of axon guidance (GO:1902668)2.56303577
98estrogen biosynthetic process (GO:0006703)2.54852901
99response to histamine (GO:0034776)2.54393227
100regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108)2.54117480

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human8.50648674
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse4.93485295
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.06346421
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.45100605
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.27691024
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.83719946
7CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.77245742
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.41233690
9ZNF274_21170338_ChIP-Seq_K562_Hela2.39159247
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.37885867
11RNF2_27304074_Chip-Seq_NSC_Mouse2.22902244
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.08943593
13REST_18959480_ChIP-ChIP_MESCs_Mouse2.04640732
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.01444906
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.96829779
16FUS_26573619_Chip-Seq_HEK293_Human1.95499220
17JARID2_20064375_ChIP-Seq_MESCs_Mouse1.88320383
18BP1_19119308_ChIP-ChIP_Hs578T_Human1.86060866
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.85000083
20TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.84376682
21REST_21632747_ChIP-Seq_MESCs_Mouse1.82551724
22TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.63700915
23GATA1_26923725_Chip-Seq_HPCs_Mouse1.63333142
24EED_16625203_ChIP-ChIP_MESCs_Mouse1.61174038
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.57706528
26EST1_17652178_ChIP-ChIP_JURKAT_Human1.57280771
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55404488
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.55283705
29GBX2_23144817_ChIP-Seq_PC3_Human1.52379456
30JARID2_20075857_ChIP-Seq_MESCs_Mouse1.50553688
31JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.47366699
32GABP_17652178_ChIP-ChIP_JURKAT_Human1.44824396
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.40786805
34SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.40144315
35FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.38388970
36TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37787965
37POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.37787965
38SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.35180086
39PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.33996870
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.32537459
41EZH2_27294783_Chip-Seq_ESCs_Mouse1.31126606
42EZH2_18974828_ChIP-Seq_MESCs_Mouse1.26376670
43RNF2_18974828_ChIP-Seq_MESCs_Mouse1.26376670
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.24904028
45CTBP1_25329375_ChIP-Seq_LNCAP_Human1.24606427
46RNF2_27304074_Chip-Seq_ESCs_Mouse1.24235374
47IKZF1_21737484_ChIP-ChIP_HCT116_Human1.24146033
48IRF1_19129219_ChIP-ChIP_H3396_Human1.23276908
49IGF1R_20145208_ChIP-Seq_DFB_Human1.21623200
50PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.17876930
51THAP11_20581084_ChIP-Seq_MESCs_Mouse1.16478690
52SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16374707
53TP53_22573176_ChIP-Seq_HFKS_Human1.16101872
54SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.15174287
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.12339307
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.11402088
57ERA_21632823_ChIP-Seq_H3396_Human1.11171214
58RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.10920553
59SUZ12_27294783_Chip-Seq_ESCs_Mouse1.09847957
60CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.04533200
61SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03780675
62MYC_18940864_ChIP-ChIP_HL60_Human1.02026957
63SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.99386660
64SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.99207508
65CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96184473
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95733739
67FOXH1_21741376_ChIP-Seq_EPCs_Human0.94554298
68ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.92998373
69TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.92284465
70OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.91101695
71SMAD4_21799915_ChIP-Seq_A2780_Human0.90411300
72RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89326879
73E2F1_17053090_ChIP-ChIP_MCF-7_Human0.88059505
74JUN_21703547_ChIP-Seq_K562_Human0.84795801
75HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.84469624
76TOP2B_26459242_ChIP-Seq_MCF-7_Human0.84114867
77CREB1_15753290_ChIP-ChIP_HEK293T_Human0.84099751
78GATA3_21878914_ChIP-Seq_MCF-7_Human0.83147844
79TDRD3_21172665_ChIP-Seq_MCF-7_Human0.83027391
80GABP_19822575_ChIP-Seq_HepG2_Human0.82912640
81SRF_21415370_ChIP-Seq_HL-1_Mouse0.82906292
82EWS_26573619_Chip-Seq_HEK293_Human0.81919174
83NCOR_22424771_ChIP-Seq_293T_Human0.81366869
84TAL1_26923725_Chip-Seq_HPCs_Mouse0.80904483
85ELK1_19687146_ChIP-ChIP_HELA_Human0.80886775
86SOX2_19829295_ChIP-Seq_ESCs_Human0.80353458
87NANOG_19829295_ChIP-Seq_ESCs_Human0.80353458
88YY1_21170310_ChIP-Seq_MESCs_Mouse0.79987727
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.79680873
90ZFP57_27257070_Chip-Seq_ESCs_Mouse0.79048412
91P300_19829295_ChIP-Seq_ESCs_Human0.78548078
92FLI1_27457419_Chip-Seq_LIVER_Mouse0.78505679
93STAT3_23295773_ChIP-Seq_U87_Human0.77190829
94MTF2_20144788_ChIP-Seq_MESCs_Mouse0.76639412
95AR_25329375_ChIP-Seq_VCAP_Human0.74983235
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.74595337
97VDR_23849224_ChIP-Seq_CD4+_Human0.73976449
98VDR_22108803_ChIP-Seq_LS180_Human0.73785376
99PCGF2_27294783_Chip-Seq_ESCs_Mouse0.73763232
100FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.73077381

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy4.50054833
2MP0008789_abnormal_olfactory_epithelium4.14756261
3MP0005499_abnormal_olfactory_system3.73909000
4MP0005394_taste/olfaction_phenotype3.73909000
5MP0002163_abnormal_gland_morphology3.66280452
6MP0005379_endocrine/exocrine_gland_phen2.87708551
7MP0008877_abnormal_DNA_methylation2.85584774
8MP0001542_abnormal_bone_strength2.82314522
9MP0002160_abnormal_reproductive_system2.72423682
10MP0005645_abnormal_hypothalamus_physiol2.61962445
11MP0002102_abnormal_ear_morphology2.52973188
12MP0003880_abnormal_central_pattern2.33385170
13MP0003315_abnormal_perineum_morphology2.33102747
14MP0000778_abnormal_nervous_system2.27141691
15MP0006276_abnormal_autonomic_nervous2.10801721
16MP0003122_maternal_imprinting2.04617309
17MP0002653_abnormal_ependyma_morphology2.02570607
18MP0003123_paternal_imprinting1.92304464
19MP0009046_muscle_twitch1.89496774
20MP0004130_abnormal_muscle_cell1.87927504
21MP0004859_abnormal_synaptic_plasticity1.85685457
22MP0002272_abnormal_nervous_system1.84526748
23MP0002184_abnormal_innervation1.81557834
24MP0004270_analgesia1.77631535
25MP0002837_dystrophic_cardiac_calcinosis1.76633395
26MP0003787_abnormal_imprinting1.74250021
27MP0004147_increased_porphyrin_level1.71847007
28MP0005389_reproductive_system_phenotype1.71214637
29MP0005551_abnormal_eye_electrophysiolog1.68437148
30MP0001529_abnormal_vocalization1.65430105
31MP0001188_hyperpigmentation1.62637714
32MP0003121_genomic_imprinting1.60878986
33MP0002210_abnormal_sex_determination1.58729259
34MP0005410_abnormal_fertilization1.58319758
35MP0003635_abnormal_synaptic_transmissio1.55661527
36MP0004858_abnormal_nervous_system1.53668639
37MP0004811_abnormal_neuron_physiology1.44008403
38MP0002752_abnormal_somatic_nervous1.41350223
39MP0008058_abnormal_DNA_repair1.40803056
40MP0003646_muscle_fatigue1.38802657
41MP0002882_abnormal_neuron_morphology1.37808675
42MP0009745_abnormal_behavioral_response1.36593082
43MP0002064_seizures1.34063570
44MP0002557_abnormal_social/conspecific_i1.32743646
45MP0005646_abnormal_pituitary_gland1.31886424
46MP0002733_abnormal_thermal_nociception1.30414727
47MP0005423_abnormal_somatic_nervous1.29515361
48MP0003890_abnormal_embryonic-extraembry1.28768347
49MP0000955_abnormal_spinal_cord1.27955569
50MP0005195_abnormal_posterior_eye1.26187174
51MP0002063_abnormal_learning/memory/cond1.25962614
52MP0001986_abnormal_taste_sensitivity1.24873808
53MP0003632_abnormal_nervous_system1.24566351
54MP0003045_fibrosis1.21446204
55MP0001929_abnormal_gametogenesis1.20649149
56MP0002909_abnormal_adrenal_gland1.18658724
57MP0001145_abnormal_male_reproductive1.18186249
58MP0002572_abnormal_emotion/affect_behav1.16265545
59MP0003698_abnormal_male_reproductive1.14931468
60MP0002233_abnormal_nose_morphology1.13645784
61MP0000653_abnormal_sex_gland1.12831058
62MP0006036_abnormal_mitochondrial_physio1.12193692
63MP0004142_abnormal_muscle_tone1.07904664
64MP0001970_abnormal_pain_threshold1.06492969
65MP0002229_neurodegeneration1.05922003
66MP0003011_delayed_dark_adaptation1.03417516
67MP0000372_irregular_coat_pigmentation1.01819462
68MP0003879_abnormal_hair_cell0.99773529
69MP0002735_abnormal_chemical_nociception0.99745909
70MP0004924_abnormal_behavior0.98373499
71MP0005386_behavior/neurological_phenoty0.98373499
72MP0006072_abnormal_retinal_apoptosis0.97475697
73MP0004145_abnormal_muscle_electrophysio0.97411908
74MP0001905_abnormal_dopamine_level0.96574050
75MP0002734_abnormal_mechanical_nocicepti0.95235583
76MP0003329_amyloid_beta_deposits0.92640802
77MP0005253_abnormal_eye_physiology0.90466615
78MP0002152_abnormal_brain_morphology0.89774468
79MP0000427_abnormal_hair_cycle0.84611412
80MP0005083_abnormal_biliary_tract0.84251731
81MP0004885_abnormal_endolymph0.80580360
82MP0003718_maternal_effect0.80416562
83MP0003861_abnormal_nervous_system0.79590675
84MP0003631_nervous_system_phenotype0.79358530
85MP0000003_abnormal_adipose_tissue0.78657544
86MP0001486_abnormal_startle_reflex0.77200131
87MP0002066_abnormal_motor_capabilities/c0.76668001
88MP0004133_heterotaxia0.74185842
89MP0002067_abnormal_sensory_capabilities0.71938571
90MP0001984_abnormal_olfaction0.71038094
91MP0005408_hypopigmentation0.70595437
92MP0002876_abnormal_thyroid_physiology0.68688096
93MP0001119_abnormal_female_reproductive0.63947143
94MP0005058_abnormal_lysosome_morphology0.63708060
95MP0001286_abnormal_eye_development0.62153540
96MP0001919_abnormal_reproductive_system0.62068446
97MP0005248_abnormal_Harderian_gland0.60404593
98MP0002161_abnormal_fertility/fecundity0.56981548
99MP0000026_abnormal_inner_ear0.56095129
100MP0001963_abnormal_hearing_physiology0.54651523

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.37370294
2Bony spicule pigmentary retinopathy (HP:0007737)5.20220615
3Polyphagia (HP:0002591)4.41479259
4Hypoplasia of the uterus (HP:0000013)4.29522063
5Acute necrotizing encephalopathy (HP:0006965)3.85319518
6Methylmalonic acidemia (HP:0002912)3.83355547
7Sex reversal (HP:0012245)3.70009222
8Abnormal sex determination (HP:0012244)3.70009222
9Intestinal atresia (HP:0011100)3.53783448
10Abnormal mitochondria in muscle tissue (HP:0008316)3.47840234
113-Methylglutaconic aciduria (HP:0003535)3.46674529
12Impaired vibration sensation in the lower limbs (HP:0002166)3.43400229
13Osteomalacia (HP:0002749)3.38684296
14Methylmalonic aciduria (HP:0012120)3.38671064
15Mitochondrial inheritance (HP:0001427)3.33649215
16Medial flaring of the eyebrow (HP:0010747)3.31268630
17Progressive macrocephaly (HP:0004481)3.23380041
18Gait imbalance (HP:0002141)3.20766534
19Abnormality of renal resorption (HP:0011038)3.15510525
20Increased hepatocellular lipid droplets (HP:0006565)3.09554117
21Abnormality of the corticospinal tract (HP:0002492)3.06997426
22Progressive cerebellar ataxia (HP:0002073)3.06582357
23Pancreatic fibrosis (HP:0100732)3.02830763
24Abnormal ciliary motility (HP:0012262)2.93778559
25Aplasia/hypoplasia of the uterus (HP:0008684)2.89673116
26Renal Fanconi syndrome (HP:0001994)2.83846790
27Congenital primary aphakia (HP:0007707)2.82021519
28Acute encephalopathy (HP:0006846)2.81294613
29Increased CSF lactate (HP:0002490)2.74143398
30Hypoplasia of the brainstem (HP:0002365)2.73371033
31Aplasia/Hypoplasia of the brainstem (HP:0007362)2.73371033
32Aplasia/Hypoplasia of the tibia (HP:0005772)2.69322495
33Poor suck (HP:0002033)2.67959793
34Nephrogenic diabetes insipidus (HP:0009806)2.64236937
35Hepatic necrosis (HP:0002605)2.62661274
36Hepatocellular necrosis (HP:0001404)2.60287804
37Rib fusion (HP:0000902)2.57555436
38Hand muscle atrophy (HP:0009130)2.49363639
39Lipid accumulation in hepatocytes (HP:0006561)2.48807429
40True hermaphroditism (HP:0010459)2.48310135
41Hyperthyroidism (HP:0000836)2.46856568
42Abnormal rod and cone electroretinograms (HP:0008323)2.42518937
43Agitation (HP:0000713)2.38122136
44Short tibia (HP:0005736)2.36384429
45Increased intramyocellular lipid droplets (HP:0012240)2.35353845
46Gaze-evoked nystagmus (HP:0000640)2.34889635
47Abnormality of urine glucose concentration (HP:0011016)2.32744881
48Glycosuria (HP:0003076)2.32744881
49Pachygyria (HP:0001302)2.32282622
50Abnormality of cells of the erythroid lineage (HP:0012130)2.28732479
51Congenital stationary night blindness (HP:0007642)2.28518080
52Spastic tetraparesis (HP:0001285)2.28508572
53Abnormality of vitamin B metabolism (HP:0004340)2.22387405
54Abnormal eating behavior (HP:0100738)2.20655258
55Gonadal dysgenesis (HP:0000133)2.20331942
56Renal cortical cysts (HP:0000803)2.19715976
57Poor coordination (HP:0002370)2.19428514
58Occipital encephalocele (HP:0002085)2.19003328
59Pancreatic cysts (HP:0001737)2.16757139
60Adrenal hypoplasia (HP:0000835)2.15516556
61Cerebral edema (HP:0002181)2.13570089
62Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.11493352
63Degeneration of the lateral corticospinal tracts (HP:0002314)2.11493352
64Abnormal number of erythroid precursors (HP:0012131)2.05655958
65Retinitis pigmentosa (HP:0000510)2.04975392
66Male pseudohermaphroditism (HP:0000037)2.04917152
67Exertional dyspnea (HP:0002875)2.04734821
68Aplasia/Hypoplasia of the tongue (HP:0010295)2.02805936
69Spastic tetraplegia (HP:0002510)2.02522874
70Febrile seizures (HP:0002373)2.02155421
71Abnormal hair whorl (HP:0010721)2.01804409
72Abnormality of midbrain morphology (HP:0002418)2.01476781
73Molar tooth sign on MRI (HP:0002419)2.01476781
74Abnormal respiratory motile cilium physiology (HP:0012261)1.99243019
75Sensorimotor neuropathy (HP:0007141)1.98707340
76Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.97821722
77Sclerocornea (HP:0000647)1.95889589
78Abnormality of the vitamin B12 metabolism (HP:0004341)1.93921703
79Narrow forehead (HP:0000341)1.93897175
80Abnormal urine phosphate concentration (HP:0012599)1.93080381
81Dyskinesia (HP:0100660)1.92335274
82Neonatal onset (HP:0003623)1.92329623
83Spastic gait (HP:0002064)1.92062511
84Rimmed vacuoles (HP:0003805)1.85883564
85Anencephaly (HP:0002323)1.83446345
86Astigmatism (HP:0000483)1.83308145
87Hyperglycinemia (HP:0002154)1.83282124
88Absent rod-and cone-mediated responses on ERG (HP:0007688)1.83158676
89Urinary urgency (HP:0000012)1.82931318
90Hyperphosphatemia (HP:0002905)1.82797023
91Brushfield spots (HP:0001088)1.81990902
92Anteriorly placed anus (HP:0001545)1.81322837
93Respiratory failure (HP:0002878)1.80613607
94Limb dystonia (HP:0002451)1.80064166
95Lactic acidosis (HP:0003128)1.79805039
96Abnormality of the lower motor neuron (HP:0002366)1.78610225
97Spontaneous abortion (HP:0005268)1.78260085
98Nephronophthisis (HP:0000090)1.75519019
99Generalized aminoaciduria (HP:0002909)1.74416506
100Focal dystonia (HP:0004373)1.73872988

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.05368995
2TRIM283.36402543
3MAP2K73.20500313
4STK163.08538204
5MAP3K43.08350672
6BRAF2.72287382
7MARK12.64302436
8WNK32.58982185
9MINK12.33745587
10PRKCG2.06045290
11BCR2.02763477
12CDK191.95701763
13EPHB11.84022159
14NTRK31.77771631
15STK381.73830270
16OXSR11.71535711
17FRK1.69714421
18DYRK21.67425510
19WNK41.63978060
20GRK11.60763091
21MAPK131.58611272
22SIK21.54006988
23RPS6KA21.53853162
24STK391.30039560
25PHKG11.28235073
26PHKG21.28235073
27SGK4941.27433456
28SGK2231.27433456
29MAP3K61.25240593
30VRK11.24177137
31CSNK1G31.22686073
32MAP2K41.22253122
33CDK141.15120085
34CSNK1A1L1.11031631
35EPHA41.09106709
36TNK21.08736500
37CSNK1G21.06891977
38PAK31.03423928
39SGK21.01464579
40MAP2K21.00958862
41NME20.98822802
42PRKD30.97172707
43ZAK0.96620635
44EIF2AK10.95028029
45CSNK1E0.94286927
46CSNK1G10.93304081
47CDK50.89871274
48EPHB20.89596024
49CAMKK20.88349873
50CDK180.87283629
51DAPK10.87268473
52CDK150.87113610
53LIMK10.86555372
54PNCK0.85963225
55BRSK10.85282822
56TNIK0.85135362
57DYRK30.84584336
58DYRK1B0.81331858
59SGK10.78705626
60PRKG10.73768583
61NTRK20.73744514
62CDK11A0.72103144
63UHMK10.71958608
64ATR0.71309871
65INSRR0.69193181
66ADRBK20.65559223
67CASK0.65131872
68STK110.64910305
69PRKACA0.64376928
70CSNK1A10.63075092
71PRKCH0.61146238
72PLK20.59437908
73CAMK2A0.58457181
74PAK60.58198094
75KSR10.56807329
76PLK10.56638923
77RPS6KA50.56508352
78MAP3K50.55581492
79MAPK150.54936118
80RIPK10.53850744
81CLK10.52225006
82PDK10.51418340
83PRKCB0.50661484
84DYRK1A0.49554088
85CAMKK10.49189707
86MAPKAPK30.48887468
87RPS6KA30.46906879
88PRKDC0.46711469
89PRKCE0.46437444
90WEE10.44359451
91PLK30.43551969
92NEK90.43467119
93TIE10.43246831
94PINK10.43206107
95RPS6KA60.43159198
96CHEK20.40798219
97MARK30.40667050
98TYRO30.38422229
99PRKCD0.37457325
100CDK10.37455412

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.05309783
2Oxidative phosphorylation_Homo sapiens_hsa001904.04379592
3Parkinsons disease_Homo sapiens_hsa050123.59649014
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.57915982
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.53354523
6Cardiac muscle contraction_Homo sapiens_hsa042602.83133817
7Steroid biosynthesis_Homo sapiens_hsa001002.62083777
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.27755325
9Huntingtons disease_Homo sapiens_hsa050162.27412597
10Protein export_Homo sapiens_hsa030602.25798537
11Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.25616484
12Alzheimers disease_Homo sapiens_hsa050102.22340425
13Nicotine addiction_Homo sapiens_hsa050332.15100708
14GABAergic synapse_Homo sapiens_hsa047272.05458725
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.95650803
16Butanoate metabolism_Homo sapiens_hsa006501.94546746
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.93515029
18Morphine addiction_Homo sapiens_hsa050321.90558684
19Synaptic vesicle cycle_Homo sapiens_hsa047211.89282332
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.81615605
21Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.79178909
22Taste transduction_Homo sapiens_hsa047421.76617490
23Collecting duct acid secretion_Homo sapiens_hsa049661.66375213
24Fatty acid elongation_Homo sapiens_hsa000621.56286326
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.52457325
26Homologous recombination_Homo sapiens_hsa034401.45201991
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.19681845
28Olfactory transduction_Homo sapiens_hsa047401.19474058
29Dopaminergic synapse_Homo sapiens_hsa047281.19045440
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.03720708
31Serotonergic synapse_Homo sapiens_hsa047261.00786999
32Fatty acid metabolism_Homo sapiens_hsa012120.99326452
33Ribosome_Homo sapiens_hsa030100.98704808
34Insulin secretion_Homo sapiens_hsa049110.97671498
35Sulfur relay system_Homo sapiens_hsa041220.95825786
36Hedgehog signaling pathway_Homo sapiens_hsa043400.93726039
37Circadian entrainment_Homo sapiens_hsa047130.92175576
38Fanconi anemia pathway_Homo sapiens_hsa034600.91344227
39Oocyte meiosis_Homo sapiens_hsa041140.91230723
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90581007
41Ether lipid metabolism_Homo sapiens_hsa005650.90389369
42Peroxisome_Homo sapiens_hsa041460.90353309
43Glycerolipid metabolism_Homo sapiens_hsa005610.90058195
44Glutamatergic synapse_Homo sapiens_hsa047240.88944594
45Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87669183
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.85931985
47Axon guidance_Homo sapiens_hsa043600.84047205
48Base excision repair_Homo sapiens_hsa034100.76452432
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.75459795
50Linoleic acid metabolism_Homo sapiens_hsa005910.72818819
51Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.71594414
52Long-term depression_Homo sapiens_hsa047300.65541515
53Cocaine addiction_Homo sapiens_hsa050300.65027185
54Non-homologous end-joining_Homo sapiens_hsa034500.65001389
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64891878
56Pyruvate metabolism_Homo sapiens_hsa006200.63758491
57Metabolic pathways_Homo sapiens_hsa011000.62063922
58Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.61088747
59Vibrio cholerae infection_Homo sapiens_hsa051100.59999291
60Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.59451743
61Fatty acid degradation_Homo sapiens_hsa000710.57606324
62cAMP signaling pathway_Homo sapiens_hsa040240.55761749
63Alcoholism_Homo sapiens_hsa050340.52253211
64Mineral absorption_Homo sapiens_hsa049780.50595598
65Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49578305
66Mismatch repair_Homo sapiens_hsa034300.48574123
67Gap junction_Homo sapiens_hsa045400.47613517
68Oxytocin signaling pathway_Homo sapiens_hsa049210.46699284
69Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.46640423
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.45335674
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43512593
72Propanoate metabolism_Homo sapiens_hsa006400.43298299
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41846607
74Nucleotide excision repair_Homo sapiens_hsa034200.39600164
75Cholinergic synapse_Homo sapiens_hsa047250.39453564
76Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.38458205
77Cyanoamino acid metabolism_Homo sapiens_hsa004600.37455914
78Basal transcription factors_Homo sapiens_hsa030220.36286909
79RNA transport_Homo sapiens_hsa030130.35958566
80Long-term potentiation_Homo sapiens_hsa047200.34978494
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.34746573
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.34682332
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.34109800
84Proteasome_Homo sapiens_hsa030500.32618768
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.32581497
86Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.31436918
87Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31368171
88Calcium signaling pathway_Homo sapiens_hsa040200.31007737
89MAPK signaling pathway_Homo sapiens_hsa040100.30294907
90Tryptophan metabolism_Homo sapiens_hsa003800.30282173
91Salivary secretion_Homo sapiens_hsa049700.30077661
92Pyrimidine metabolism_Homo sapiens_hsa002400.26777844
93Amphetamine addiction_Homo sapiens_hsa050310.26636838
94Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.25818854
95Fat digestion and absorption_Homo sapiens_hsa049750.25324995
96RNA degradation_Homo sapiens_hsa030180.24204378
97Dilated cardiomyopathy_Homo sapiens_hsa054140.24185460
98Melanogenesis_Homo sapiens_hsa049160.22044344
99Purine metabolism_Homo sapiens_hsa002300.20071907
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.19802880

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