ZNF629

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1planar cell polarity pathway involved in neural tube closure (GO:0090179)4.32630576
2regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.93438674
3semaphorin-plexin signaling pathway (GO:0071526)3.71358268
4cell migration in hindbrain (GO:0021535)3.64073273
5regulation of NFAT protein import into nucleus (GO:0051532)3.45324072
6regulation of mammary gland epithelial cell proliferation (GO:0033599)3.26426913
7neuron projection extension involved in neuron projection guidance (GO:1902284)3.20001368
8axon extension involved in axon guidance (GO:0048846)3.20001368
9convergent extension (GO:0060026)3.18282502
10paraxial mesoderm development (GO:0048339)3.13792877
11protein retention in ER lumen (GO:0006621)3.12369457
12positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.11386675
13cell-cell junction maintenance (GO:0045217)3.03883874
14dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.03746960
15DNA strand renaturation (GO:0000733)2.98863990
16camera-type eye morphogenesis (GO:0048593)2.98025800
17heterochromatin organization (GO:0070828)2.95823108
18cranial nerve morphogenesis (GO:0021602)2.95417534
19adherens junction assembly (GO:0034333)2.93166881
20Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.87977227
21skeletal muscle organ development (GO:0060538)2.84038772
22maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.76892275
23diaphragm development (GO:0060539)2.76228986
24G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.72890487
25regulation of establishment of planar polarity (GO:0090175)2.70410563
26negative regulation of catenin import into nucleus (GO:0035414)2.65789705
27body morphogenesis (GO:0010171)2.63528078
28axon extension (GO:0048675)2.62360284
29protein-DNA complex disassembly (GO:0032986)2.61686178
30nucleosome disassembly (GO:0006337)2.61686178
31cell-substrate adherens junction assembly (GO:0007045)2.61377372
32focal adhesion assembly (GO:0048041)2.61377372
33hippo signaling (GO:0035329)2.60192974
34establishment of monopolar cell polarity (GO:0061162)2.55865374
35establishment or maintenance of monopolar cell polarity (GO:0061339)2.55865374
36atrial septum morphogenesis (GO:0060413)2.54068343
37cochlea morphogenesis (GO:0090103)2.51236618
38peptidyl-glutamic acid carboxylation (GO:0017187)2.48110046
39protein carboxylation (GO:0018214)2.48110046
40regulation of synapse structural plasticity (GO:0051823)2.47765202
41negative regulation of cell size (GO:0045792)2.47391320
42regulation of cholesterol biosynthetic process (GO:0045540)2.47085290
43protein complex localization (GO:0031503)2.43942273
44axonal fasciculation (GO:0007413)2.43772977
45cellular protein complex localization (GO:0034629)2.42328256
46adenine nucleotide transport (GO:0051503)2.40546363
47regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.39511357
48regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.37736909
49establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.37414990
50establishment of apical/basal cell polarity (GO:0035089)2.36640171
51mitochondrion transport along microtubule (GO:0047497)2.34789521
52establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.34789521
53regulation of axon extension involved in axon guidance (GO:0048841)2.34648625
54basement membrane organization (GO:0071711)2.34167340
55eye morphogenesis (GO:0048592)2.34089309
56atrioventricular valve morphogenesis (GO:0003181)2.33956086
57embryonic body morphogenesis (GO:0010172)2.32260870
58non-canonical Wnt signaling pathway (GO:0035567)2.32196826
59proline biosynthetic process (GO:0006561)2.31867685
60cell junction maintenance (GO:0034331)2.28939965
61myelination in peripheral nervous system (GO:0022011)2.28354514
62peripheral nervous system axon ensheathment (GO:0032292)2.28354514
63regulation of cardioblast differentiation (GO:0051890)2.26548110
64embryonic skeletal joint morphogenesis (GO:0060272)2.26153683
65neural tube development (GO:0021915)2.25703921
66establishment of tissue polarity (GO:0007164)2.25222028
67establishment of planar polarity (GO:0001736)2.25222028
68mRNA stabilization (GO:0048255)2.22063069
69RNA stabilization (GO:0043489)2.22063069
70negative regulation of fatty acid transport (GO:2000192)2.19738486
71positive regulation of cell size (GO:0045793)2.18765657
72positive regulation of canonical Wnt signaling pathway (GO:0090263)2.18583086
73cardiac myofibril assembly (GO:0055003)2.18467193
74epithelial cell-cell adhesion (GO:0090136)2.18343056
75UV protection (GO:0009650)2.18205540
76regulation of translational fidelity (GO:0006450)2.18036954
77bone development (GO:0060348)2.17183864
78neuron recognition (GO:0008038)2.15422039
79positive regulation of axonogenesis (GO:0050772)2.15377211
80mammary gland epithelial cell differentiation (GO:0060644)2.15156060
81chromatin silencing (GO:0006342)2.13916150
82protein heterotrimerization (GO:0070208)2.13045138
83neuron projection extension (GO:1990138)2.12902185
84negative regulation of cell aging (GO:0090344)2.12421562
85protein insertion into membrane (GO:0051205)2.12256684
86histone H2B ubiquitination (GO:0033523)2.12139113
87establishment of mitochondrion localization (GO:0051654)2.11675913
88positive regulation of catecholamine secretion (GO:0033605)2.09848395
89developmental cell growth (GO:0048588)2.09544909
90regulation of axon guidance (GO:1902667)2.09292135
91ganglion development (GO:0061548)2.08953412
92proximal/distal pattern formation (GO:0009954)2.08709692
93respiratory system process (GO:0003016)2.07521089
94cell-substrate junction assembly (GO:0007044)2.07182681
95bone trabecula formation (GO:0060346)2.06906873
96lens morphogenesis in camera-type eye (GO:0002089)2.06613293
97establishment or maintenance of apical/basal cell polarity (GO:0035088)2.05890409
98establishment or maintenance of bipolar cell polarity (GO:0061245)2.05890409
99negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.05592218
100mitotic chromosome condensation (GO:0007076)2.03199080

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.99817378
2LXR_22292898_ChIP-Seq_THP-1_Human2.61628292
3ERG_21242973_ChIP-ChIP_JURKAT_Human2.50939293
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.49590888
5STAT6_21828071_ChIP-Seq_BEAS2B_Human2.45279686
6* VDR_21846776_ChIP-Seq_THP-1_Human2.42348684
7RARG_19884340_ChIP-ChIP_MEFs_Mouse2.40026449
8TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.33071265
9* KDM2B_26808549_Chip-Seq_K562_Human2.21101654
10* RACK7_27058665_Chip-Seq_MCF-7_Human2.16658465
11ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.13706785
12FOXM1_23109430_ChIP-Seq_U2OS_Human2.04127523
13ZFP281_18757296_ChIP-ChIP_E14_Mouse2.03673775
14KDM2B_26808549_Chip-Seq_SUP-B15_Human2.00489988
15EZH2_22144423_ChIP-Seq_EOC_Human1.95442479
16DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.92320618
17WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.90544259
18* P68_20966046_ChIP-Seq_HELA_Human1.82721732
19KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.82424897
20* XRN2_22483619_ChIP-Seq_HELA_Human1.80255325
21TP63_17297297_ChIP-ChIP_HaCaT_Human1.78885836
22* KDM2B_26808549_Chip-Seq_DND41_Human1.77161038
23EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.76356651
24ELK3_25401928_ChIP-Seq_HUVEC_Human1.75900492
25CTCF_27219007_Chip-Seq_Bcells_Human1.71679811
26TET1_21451524_ChIP-Seq_MESCs_Mouse1.71558624
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.71086609
28CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.69720910
29ZFP281_27345836_Chip-Seq_ESCs_Mouse1.69199661
30ESR2_21235772_ChIP-Seq_MCF-7_Human1.67301043
31DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.65693948
32RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.64291032
33TP53_22127205_ChIP-Seq_IMR90_Human1.63436348
34CREB1_26743006_Chip-Seq_LNCaP_Human1.63322155
35ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.62962701
36* SMC4_20622854_ChIP-Seq_HELA_Human1.62448382
37MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.62305601
38TP63_19390658_ChIP-ChIP_HaCaT_Human1.60967176
39E2F7_22180533_ChIP-Seq_HELA_Human1.58043028
40UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.56686567
41CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.56662138
42ESR1_15608294_ChIP-ChIP_MCF-7_Human1.56479716
43ZNF263_19887448_ChIP-Seq_K562_Human1.55069981
44THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.54216070
45CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.52557152
46RNF2_18974828_ChIP-Seq_MESCs_Mouse1.51330438
47EZH2_18974828_ChIP-Seq_MESCs_Mouse1.51330438
48CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.49183250
49EZH2_27304074_Chip-Seq_ESCs_Mouse1.49149553
50MYC_22102868_ChIP-Seq_BL_Human1.48333213
51ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47229195
52OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.45091458
53SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.43252812
54SA1_27219007_Chip-Seq_ERYTHROID_Human1.40705253
55KDM2B_26808549_Chip-Seq_JURKAT_Human1.39913749
56MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.38796554
57JARID2_20075857_ChIP-Seq_MESCs_Mouse1.38392665
58TP53_20018659_ChIP-ChIP_R1E_Mouse1.37814699
59CTCF_27219007_Chip-Seq_ERYTHROID_Human1.36950852
60P300_27058665_Chip-Seq_ZR-75-30cells_Human1.36712990
61EED_16625203_ChIP-ChIP_MESCs_Mouse1.33359247
62TCF7_22412390_ChIP-Seq_EML_Mouse1.30882492
63EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.30495241
64HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.29244405
65EZH2_27294783_Chip-Seq_ESCs_Mouse1.29087855
66RNF2_27304074_Chip-Seq_ESCs_Mouse1.26054524
67PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25908242
68DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24310272
69SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22932449
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.22203635
71JARID2_20064375_ChIP-Seq_MESCs_Mouse1.21842103
72RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.21377864
73SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.21169190
74UBF1/2_26484160_Chip-Seq_HMECs_Human1.19936845
75* RUNX1_27514584_Chip-Seq_MCF-7_Human1.19393540
76SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.19375037
77NFIB_24661679_ChIP-Seq_LUNG_Mouse1.19235184
78RARA_24833708_ChIP-Seq_LIVER_Mouse1.18625982
79TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17689601
80SRY_22984422_ChIP-ChIP_TESTIS_Rat1.16997549
81CLOCK_20551151_ChIP-Seq_293T_Human1.16235237
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.15636425
83KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14894758
84CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.13998010
85RING1B_27294783_Chip-Seq_NPCs_Mouse1.13444104
86FOXP1_21924763_ChIP-Seq_HESCs_Human1.13046684
87SOX3_22085726_ChIP-Seq_NPCs_Mouse1.12785807
88DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.10666955
89STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.09636560
90RARB_27405468_Chip-Seq_BRAIN_Mouse1.09186963
91KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.07186787
92SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.06492276
93ATF3_27146783_Chip-Seq_COLON_Human1.05162098
94TP53_23651856_ChIP-Seq_MEFs_Mouse1.04242297
95RING1B_27294783_Chip-Seq_ESCs_Mouse1.03853549
96PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.02391083
97RARB_24833708_ChIP-Seq_LIVER_Mouse1.01109158
98PKCTHETA_26484144_Chip-Seq_BREAST_Human1.00413827
99TET1_21490601_ChIP-Seq_MESCs_Mouse1.00178824
100* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00039461

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.47992675
2MP0005409_darkened_coat_color2.95025962
3MP0000566_synostosis2.67678523
4MP0010030_abnormal_orbit_morphology2.57166302
5MP0005423_abnormal_somatic_nervous2.36817035
6MP0000537_abnormal_urethra_morphology2.32208663
7MP0005171_absent_coat_pigmentation2.31446211
8MP0004858_abnormal_nervous_system2.22767026
9MP0005257_abnormal_intraocular_pressure2.18501751
10MP0005076_abnormal_cell_differentiation2.10917316
11MP0002249_abnormal_larynx_morphology2.09436831
12MP0000751_myopathy2.08076685
13MP0004233_abnormal_muscle_weight1.97387942
14MP0003942_abnormal_urinary_system1.90871990
15MP0009053_abnormal_anal_canal1.84911206
16MP0003123_paternal_imprinting1.64407211
17MP0001188_hyperpigmentation1.63570364
18MP0005623_abnormal_meninges_morphology1.62821081
19MP0000534_abnormal_ureter_morphology1.60847503
20MP0003136_yellow_coat_color1.56792914
21MP0000750_abnormal_muscle_regeneration1.54575456
22MP0003385_abnormal_body_wall1.53058663
23MP0001299_abnormal_eye_distance/1.44283491
24MP0000733_abnormal_muscle_development1.42208428
25MP0010368_abnormal_lymphatic_system1.41388699
26MP0004272_abnormal_basement_membrane1.40765735
27MP0000778_abnormal_nervous_system1.40432833
28MP0003315_abnormal_perineum_morphology1.40019237
29MP0001849_ear_inflammation1.38507139
30MP0001346_abnormal_lacrimal_gland1.35719866
31MP0003937_abnormal_limbs/digits/tail_de1.34059789
32MP0002697_abnormal_eye_size1.30401628
33MP0003283_abnormal_digestive_organ1.29070222
34MP0000579_abnormal_nail_morphology1.26152652
35MP0000049_abnormal_middle_ear1.25030944
36MP0009384_cardiac_valve_regurgitation1.25015677
37MP0008438_abnormal_cutaneous_collagen1.24457290
38MP0002092_abnormal_eye_morphology1.22809723
39MP0001348_abnormal_lacrimal_gland1.22120201
40MP0000462_abnormal_digestive_system1.18655040
41MP0000747_muscle_weakness1.17990556
42MP0003111_abnormal_nucleus_morphology1.16777926
43MP0000003_abnormal_adipose_tissue1.16522601
44MP0002116_abnormal_craniofacial_bone1.16417474
45MP0003935_abnormal_craniofacial_develop1.15495220
46MP0002233_abnormal_nose_morphology1.15432206
47MP0003861_abnormal_nervous_system1.14747032
48MP0009250_abnormal_appendicular_skeleto1.14232095
49MP0000428_abnormal_craniofacial_morphol1.14135938
50MP0003115_abnormal_respiratory_system1.12347798
51MP0005503_abnormal_tendon_morphology1.10415010
52MP0003755_abnormal_palate_morphology1.09013178
53MP0001661_extended_life_span1.06560872
54MP0003453_abnormal_keratinocyte_physiol1.05626281
55MP0005058_abnormal_lysosome_morphology1.04387644
56MP0005174_abnormal_tail_pigmentation1.03671226
57MP0004087_abnormal_muscle_fiber1.02716315
58MP0004185_abnormal_adipocyte_glucose1.00714681
59MP0000759_abnormal_skeletal_muscle1.00600171
60MP0005330_cardiomyopathy1.00084103
61MP0000762_abnormal_tongue_morphology0.99714454
62MP0002084_abnormal_developmental_patter0.98440581
63MP0002085_abnormal_embryonic_tissue0.98139154
64MP0003119_abnormal_digestive_system0.96444533
65MP0010630_abnormal_cardiac_muscle0.96147757
66MP0000538_abnormal_urinary_bladder0.95562456
67MP0002932_abnormal_joint_morphology0.94843747
68MP0004197_abnormal_fetal_growth/weight/0.94513438
69MP0002234_abnormal_pharynx_morphology0.94334308
70MP0000955_abnormal_spinal_cord0.93444841
71MP0004859_abnormal_synaptic_plasticity0.91939137
72MP0009672_abnormal_birth_weight0.90323247
73MP0002081_perinatal_lethality0.89132089
74MP0000432_abnormal_head_morphology0.88641698
75MP0002184_abnormal_innervation0.88276806
76MP0002089_abnormal_postnatal_growth/wei0.87426715
77MP0002108_abnormal_muscle_morphology0.86948209
78MP0002114_abnormal_axial_skeleton0.85723309
79MP0002160_abnormal_reproductive_system0.85573650
80MP0005508_abnormal_skeleton_morphology0.85443788
81MP0001502_abnormal_circadian_rhythm0.85201943
82MP0000767_abnormal_smooth_muscle0.85125477
83MP0001672_abnormal_embryogenesis/_devel0.84940742
84MP0005380_embryogenesis_phenotype0.84940742
85MP0002111_abnormal_tail_morphology0.84691284
86MP0004130_abnormal_muscle_cell0.84631934
87MP0005197_abnormal_uvea_morphology0.83970620
88MP0000678_abnormal_parathyroid_gland0.83608686
89MP0003984_embryonic_growth_retardation0.82998644
90MP0002152_abnormal_brain_morphology0.82697632
91MP0009780_abnormal_chondrocyte_physiolo0.80125961
92MP0003941_abnormal_skin_development0.79162777
93MP0002088_abnormal_embryonic_growth/wei0.78454277
94MP0003091_abnormal_cell_migration0.77906983
95MP0001270_distended_abdomen0.76980087
96MP0003279_aneurysm0.76925378
97MP0000467_abnormal_esophagus_morphology0.76263498
98MP0001293_anophthalmia0.75472946
99MP0005501_abnormal_skin_physiology0.73287129
100MP0003890_abnormal_embryonic-extraembry0.72437429

Predicted human phenotypes

RankGene SetZ-score
1Turricephaly (HP:0000262)4.46247313
2Ulnar bowing (HP:0003031)4.22555457
3Intestinal fistula (HP:0100819)3.34001010
4Hyperacusis (HP:0010780)3.30296416
5Rib fusion (HP:0000902)3.12432540
6Coronal craniosynostosis (HP:0004440)3.04534451
7Thin bony cortex (HP:0002753)2.91865732
8Annular pancreas (HP:0001734)2.71187004
9Facial hemangioma (HP:0000329)2.59082348
10Asymmetry of the thorax (HP:0001555)2.55293610
11Popliteal pterygium (HP:0009756)2.54831035
12Thin ribs (HP:0000883)2.47639207
13Vaginal fistula (HP:0004320)2.42959012
14Pterygium (HP:0001059)2.38669624
15Shallow orbits (HP:0000586)2.38090010
16Rectovaginal fistula (HP:0000143)2.37715757
17Rectal fistula (HP:0100590)2.37715757
18Aplasia of the musculature (HP:0100854)2.30753234
19High anterior hairline (HP:0009890)2.30369918
20Fetal akinesia sequence (HP:0001989)2.25681177
21Testicular atrophy (HP:0000029)2.22601552
22Protrusio acetabuli (HP:0003179)2.22587597
23Broad distal phalanx of finger (HP:0009836)2.19827012
24Bowing of the arm (HP:0006488)2.10280471
25Bowed forearm bones (HP:0003956)2.10280471
26Long palpebral fissure (HP:0000637)2.09868099
27Akinesia (HP:0002304)2.08881616
28Partial duplication of thumb phalanx (HP:0009944)2.06314842
29Genu recurvatum (HP:0002816)2.01784735
30Abnormality of the intrinsic pathway (HP:0010989)2.01659248
31Disproportionate tall stature (HP:0001519)2.01251465
32Abnormality of the distal phalanx of the thumb (HP:0009617)2.01159312
33Choanal stenosis (HP:0000452)2.00808194
34Premature rupture of membranes (HP:0001788)1.99990926
35Renal duplication (HP:0000075)1.96522118
36Capillary hemangiomas (HP:0005306)1.95066952
37Abnormality of the aortic arch (HP:0012303)1.94549297
38Spina bifida occulta (HP:0003298)1.93722016
39Insomnia (HP:0100785)1.93282121
40Abnormality of the phalanges of the hallux (HP:0010057)1.92937574
41Sparse lateral eyebrow (HP:0005338)1.92610668
42Bladder diverticulum (HP:0000015)1.90572837
43Partial duplication of the phalanx of hand (HP:0009999)1.88811231
44Spinal rigidity (HP:0003306)1.88021245
45Aplasia involving bones of the upper limbs (HP:0009823)1.87900979
46Aplasia of the phalanges of the hand (HP:0009802)1.87900979
47Aplasia involving bones of the extremities (HP:0009825)1.87900979
48Anal stenosis (HP:0002025)1.85566587
49Slender long bone (HP:0003100)1.82191006
50Pointed chin (HP:0000307)1.80727226
51Elfin facies (HP:0004428)1.78426834
52Patellar aplasia (HP:0006443)1.75350474
53Poikiloderma (HP:0001029)1.73569562
54Renovascular hypertension (HP:0100817)1.72345339
55Broad thumb (HP:0011304)1.71238733
56Broad phalanges of the hand (HP:0009768)1.68789451
57Cerebral aneurysm (HP:0004944)1.67662602
58Self-mutilation (HP:0000742)1.67507141
59Overriding aorta (HP:0002623)1.67003624
60Transposition of the great arteries (HP:0001669)1.66847093
61Abnormal connection of the cardiac segments (HP:0011545)1.66847093
62Abnormal ventriculo-arterial connection (HP:0011563)1.66847093
63Mitral regurgitation (HP:0001653)1.66754096
64Arnold-Chiari malformation (HP:0002308)1.65716198
65Aplasia/Hypoplasia of the patella (HP:0006498)1.65290547
66Myopathic facies (HP:0002058)1.64319621
67Abnormality of the radial head (HP:0003995)1.63574310
68Trigonocephaly (HP:0000243)1.63555741
69Precocious puberty (HP:0000826)1.62517235
70Hemorrhage of the eye (HP:0011885)1.61910703
71Carpal synostosis (HP:0009702)1.61601695
72Broad finger (HP:0001500)1.61085482
73Obstructive sleep apnea (HP:0002870)1.60636981
74Preauricular pit (HP:0004467)1.60227010
75Periauricular skin pits (HP:0100277)1.60227010
76Obsessive-compulsive behavior (HP:0000722)1.60079557
77Morphological abnormality of the middle ear (HP:0008609)1.59462818
78Congenital hip dislocation (HP:0001374)1.59359619
79Short 5th finger (HP:0009237)1.57231268
80Dislocated radial head (HP:0003083)1.56484423
81Atelectasis (HP:0100750)1.54629617
82Cervical subluxation (HP:0003308)1.53998190
83Mesangial abnormality (HP:0001966)1.53790365
84Germ cell neoplasia (HP:0100728)1.53595665
85Patellar dislocation (HP:0002999)1.53092653
86Buphthalmos (HP:0000557)1.52547915
87Duplication of thumb phalanx (HP:0009942)1.52488752
88Rectal prolapse (HP:0002035)1.51060827
89Increased number of teeth (HP:0011069)1.51050491
90Anteriorly placed anus (HP:0001545)1.51012295
91Abnormality of the thoracic spine (HP:0100711)1.50444989
92Congenital glaucoma (HP:0001087)1.50232048
93Bowel diverticulosis (HP:0005222)1.47661251
94Abnormality of the fingertips (HP:0001211)1.47011045
95Wide anterior fontanel (HP:0000260)1.46823494
96Delayed epiphyseal ossification (HP:0002663)1.45844948
97Exostoses (HP:0100777)1.43768056
98Broad face (HP:0000283)1.43577104
99Broad phalanx (HP:0006009)1.43456877
100Mildly elevated creatine phosphokinase (HP:0008180)1.40869649

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.59802768
2EEF2K4.19793800
3ICK3.45700780
4MAPK152.87813786
5CDK122.74911804
6SIK12.43438503
7MAP3K102.17332623
8PKN22.05728682
9RIPK11.94452024
10CAMK1D1.94272192
11LATS21.91343464
12EPHB21.87762434
13SMG11.84096398
14CAMK1G1.80992907
15WNK41.79600328
16TTN1.77630027
17MARK11.73539547
18PDGFRA1.70369026
19MTOR1.67298324
20IRAK31.57943561
21TYRO31.45999062
22NTRK11.31881395
23RPS6KA21.26044025
24LATS11.21403502
25EPHA21.20862561
26DDR21.20086355
27NME21.13871259
28CHEK21.01433944
29CDC71.01412890
30PTK20.99760121
31MARK20.93683292
32PINK10.93516564
33MUSK0.92594905
34CCNB10.92541872
35ILK0.91592555
36DYRK1B0.90368179
37STK240.85957383
38NEK20.84208081
39CASK0.82621932
40RPS6KL10.82568694
41RPS6KC10.82568694
42SIK20.81018442
43WNK10.80373337
44NTRK20.80320763
45FGFR40.80077691
46CDK150.79591717
47PRPF4B0.78274522
48PRKD30.77999469
49CDK11A0.72896006
50CAMK40.71362677
51CDK180.70971177
52RPS6KB20.69955154
53MST1R0.69518153
54CDK70.67777553
55RPS6KA60.67414910
56MET0.67151750
57CSNK1A1L0.65425787
58IRAK20.65163112
59PRKAA10.64248270
60CDK140.64220720
61PHKG10.63490050
62PHKG20.63490050
63AURKA0.62943406
64AKT20.62770271
65DYRK30.58206984
66TTK0.58160050
67PAK20.58030286
68RET0.57150407
69CDC42BPA0.55563165
70BRD40.54300462
71SGK30.53504885
72DYRK20.51302050
73PDGFRB0.50575674
74SGK4940.49811477
75SGK2230.49811477
76PDPK10.49066512
77DMPK0.49021393
78CDK20.48446349
79CDK10.48221852
80CAMK10.47765951
81FGFR20.46367969
82CSNK1G30.45626412
83PAK40.44331533
84RPS6KB10.42755025
85BRAF0.42451772
86PRKD20.42125708
87MAPK80.42082253
88CAMKK10.41964518
89CHEK10.41545972
90CSNK1E0.41197860
91RPS6KA10.40051458
92GSK3B0.39845356
93MAP2K70.39482468
94PTK60.38966565
95BMX0.38576546
96STK390.38176268
97MAP2K40.37754258
98PIM20.36896859
99CDK40.36866779
100MINK10.36809240

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041222.24175269
2Hedgehog signaling pathway_Homo sapiens_hsa043401.86214999
3Basal cell carcinoma_Homo sapiens_hsa052171.85960475
4Lysine degradation_Homo sapiens_hsa003101.84055268
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.82838284
6Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.81955080
7Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.81434417
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.79840153
9Hippo signaling pathway_Homo sapiens_hsa043901.77090938
10Notch signaling pathway_Homo sapiens_hsa043301.74562870
11Axon guidance_Homo sapiens_hsa043601.60570202
12Bladder cancer_Homo sapiens_hsa052191.58386765
13Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.57036532
14Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.56169729
15Dilated cardiomyopathy_Homo sapiens_hsa054141.54183294
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.48637305
17Endometrial cancer_Homo sapiens_hsa052131.47476789
18Central carbon metabolism in cancer_Homo sapiens_hsa052301.42053616
19Thyroid hormone signaling pathway_Homo sapiens_hsa049191.34333475
20Glycosaminoglycan degradation_Homo sapiens_hsa005311.31676055
21mTOR signaling pathway_Homo sapiens_hsa041501.29955419
22AMPK signaling pathway_Homo sapiens_hsa041521.29800902
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.29512773
24Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.28732555
25Melanogenesis_Homo sapiens_hsa049161.27810855
26Chronic myeloid leukemia_Homo sapiens_hsa052201.27810576
27Longevity regulating pathway - mammal_Homo sapiens_hsa042111.27294169
28Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.26724470
29Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.21653409
30Glioma_Homo sapiens_hsa052141.20066003
31Thyroid cancer_Homo sapiens_hsa052161.19972775
32ECM-receptor interaction_Homo sapiens_hsa045121.19661969
33Adherens junction_Homo sapiens_hsa045201.19259847
34MicroRNAs in cancer_Homo sapiens_hsa052061.17275056
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.16312630
36Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.14327452
37Gap junction_Homo sapiens_hsa045401.10715934
38Insulin signaling pathway_Homo sapiens_hsa049101.09794310
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.08841827
40ErbB signaling pathway_Homo sapiens_hsa040121.08384124
41Other glycan degradation_Homo sapiens_hsa005111.06217518
42Fructose and mannose metabolism_Homo sapiens_hsa000511.03682952
43Arginine biosynthesis_Homo sapiens_hsa002201.02695451
44Non-small cell lung cancer_Homo sapiens_hsa052231.02140973
45Wnt signaling pathway_Homo sapiens_hsa043101.01558184
46Focal adhesion_Homo sapiens_hsa045100.99417247
47VEGF signaling pathway_Homo sapiens_hsa043700.94534268
48Biosynthesis of amino acids_Homo sapiens_hsa012300.92703629
49Colorectal cancer_Homo sapiens_hsa052100.92553096
50Proteoglycans in cancer_Homo sapiens_hsa052050.91434175
51mRNA surveillance pathway_Homo sapiens_hsa030150.90058142
52TGF-beta signaling pathway_Homo sapiens_hsa043500.90044532
53Melanoma_Homo sapiens_hsa052180.88101151
54Renal cell carcinoma_Homo sapiens_hsa052110.87301124
55Sphingolipid metabolism_Homo sapiens_hsa006000.86400196
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.84961759
57Tight junction_Homo sapiens_hsa045300.80761876
58Cell cycle_Homo sapiens_hsa041100.80757083
59Prion diseases_Homo sapiens_hsa050200.80494459
60Estrogen signaling pathway_Homo sapiens_hsa049150.78604065
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73958001
62Prostate cancer_Homo sapiens_hsa052150.72579379
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71839224
64Glucagon signaling pathway_Homo sapiens_hsa049220.71770583
65Alcoholism_Homo sapiens_hsa050340.70944755
66Inositol phosphate metabolism_Homo sapiens_hsa005620.70248226
67Small cell lung cancer_Homo sapiens_hsa052220.68025511
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65058806
69Pathways in cancer_Homo sapiens_hsa052000.64902393
70Phospholipase D signaling pathway_Homo sapiens_hsa040720.63166370
71Oxytocin signaling pathway_Homo sapiens_hsa049210.62987848
72GnRH signaling pathway_Homo sapiens_hsa049120.62562301
73Aldosterone synthesis and secretion_Homo sapiens_hsa049250.61936038
74Steroid biosynthesis_Homo sapiens_hsa001000.61371251
75Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.61206841
76Vitamin B6 metabolism_Homo sapiens_hsa007500.60995105
77Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60315241
78AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59490802
79Cocaine addiction_Homo sapiens_hsa050300.59023451
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58280166
81N-Glycan biosynthesis_Homo sapiens_hsa005100.57885958
82Pancreatic cancer_Homo sapiens_hsa052120.57013302
83Cholinergic synapse_Homo sapiens_hsa047250.55771810
84FoxO signaling pathway_Homo sapiens_hsa040680.54497404
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53172115
86Circadian rhythm_Homo sapiens_hsa047100.52761757
87PI3K-Akt signaling pathway_Homo sapiens_hsa041510.51130957
88Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50390677
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.49616036
90Choline metabolism in cancer_Homo sapiens_hsa052310.48007751
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47607765
92Insulin resistance_Homo sapiens_hsa049310.47216875
93MAPK signaling pathway_Homo sapiens_hsa040100.47172394
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.47170690
95Long-term potentiation_Homo sapiens_hsa047200.46992451
96Rap1 signaling pathway_Homo sapiens_hsa040150.46090684
97Cardiac muscle contraction_Homo sapiens_hsa042600.45497969
98Vibrio cholerae infection_Homo sapiens_hsa051100.45009288
99Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43756196
100Arginine and proline metabolism_Homo sapiens_hsa003300.43347391

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »