ZNF663P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.88664736
2nonmotile primary cilium assembly (GO:0035058)5.30974521
3presynaptic membrane assembly (GO:0097105)4.79520240
4nucleobase catabolic process (GO:0046113)4.64648832
5somite development (GO:0061053)4.52771087
6presynaptic membrane organization (GO:0097090)4.21133884
7postsynaptic membrane organization (GO:0001941)4.14774249
8neuron fate determination (GO:0048664)3.86459990
9negative regulation of inclusion body assembly (GO:0090084)3.80192840
10behavioral response to nicotine (GO:0035095)3.69259114
11cerebral cortex radially oriented cell migration (GO:0021799)3.67599046
12neuron cell-cell adhesion (GO:0007158)3.30094378
13otic vesicle formation (GO:0030916)3.25969568
14epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.24212745
15regulation of inclusion body assembly (GO:0090083)3.23443017
16regulation of telomere maintenance (GO:0032204)3.20561584
17negative regulation of DNA-dependent DNA replication (GO:2000104)3.19559517
18intraciliary transport (GO:0042073)3.19183551
19somatic diversification of immune receptors via somatic mutation (GO:0002566)3.15394542
20somatic hypermutation of immunoglobulin genes (GO:0016446)3.15394542
21regulation of cilium movement (GO:0003352)3.13507019
22limb bud formation (GO:0060174)3.11406892
23detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.07365019
24axon ensheathment in central nervous system (GO:0032291)3.06921134
25central nervous system myelination (GO:0022010)3.06921134
26retinal ganglion cell axon guidance (GO:0031290)3.05915686
27righting reflex (GO:0060013)3.05604628
28regulation of feeding behavior (GO:0060259)3.03562692
29mechanosensory behavior (GO:0007638)3.02196775
30negative regulation of telomere maintenance (GO:0032205)3.00427127
31neuronal action potential propagation (GO:0019227)2.97596861
32G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94221817
33axonal fasciculation (GO:0007413)2.92233146
34gamma-aminobutyric acid transport (GO:0015812)2.92085087
35vocalization behavior (GO:0071625)2.91503663
36dendritic spine morphogenesis (GO:0060997)2.91274016
37negative regulation of transcription regulatory region DNA binding (GO:2000678)2.87141637
38heart valve formation (GO:0003188)2.86869373
39axoneme assembly (GO:0035082)2.84809010
40seminiferous tubule development (GO:0072520)2.82925918
41calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.80615867
42neuron recognition (GO:0008038)2.78223607
43regulation of collateral sprouting (GO:0048670)2.77781108
44central nervous system projection neuron axonogenesis (GO:0021952)2.74483182
45phenylpropanoid metabolic process (GO:0009698)2.73142532
46startle response (GO:0001964)2.72536219
47cellular response to cholesterol (GO:0071397)2.71519923
48smoothened signaling pathway (GO:0007224)2.71514371
49regulation of telomere maintenance via telomerase (GO:0032210)2.71397391
50photoreceptor cell maintenance (GO:0045494)2.69424755
51cilium organization (GO:0044782)2.67688434
52cilium morphogenesis (GO:0060271)2.66381216
53cilium assembly (GO:0042384)2.64714349
54protein polyglutamylation (GO:0018095)2.62953110
55regulation of centriole replication (GO:0046599)2.61693165
56negative regulation of multicellular organism growth (GO:0040015)2.61652819
57cilium movement (GO:0003341)2.61497394
58synapse assembly (GO:0007416)2.59792920
59cochlea development (GO:0090102)2.58452073
60epithelial cilium movement (GO:0003351)2.57849752
61regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.57655399
62negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.57532911
63negative regulation of translation, ncRNA-mediated (GO:0040033)2.57532911
64regulation of translation, ncRNA-mediated (GO:0045974)2.57532911
65serotonin metabolic process (GO:0042428)2.54061103
66forebrain neuron differentiation (GO:0021879)2.53909242
67photoreceptor cell differentiation (GO:0046530)2.53890709
68eye photoreceptor cell differentiation (GO:0001754)2.53890709
69auditory behavior (GO:0031223)2.49848162
70microtubule polymerization or depolymerization (GO:0031109)2.49051193
71hindbrain development (GO:0030902)2.46297071
72regulation of non-canonical Wnt signaling pathway (GO:2000050)2.46119293
73nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.45768956
74neurotransmitter-gated ion channel clustering (GO:0072578)2.45185490
75radial glial cell differentiation (GO:0060019)2.43113458
76C4-dicarboxylate transport (GO:0015740)2.42122007
77artery development (GO:0060840)2.41963272
78inner ear receptor stereocilium organization (GO:0060122)2.41949185
79neuronal stem cell maintenance (GO:0097150)2.41931671
80ncRNA catabolic process (GO:0034661)2.41769937
81cullin deneddylation (GO:0010388)2.41752682
82retina layer formation (GO:0010842)2.40258762
83axonemal dynein complex assembly (GO:0070286)2.39569861
84microtubule severing (GO:0051013)2.38703082
85membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.38089645
86auditory receptor cell stereocilium organization (GO:0060088)2.37930786
87microtubule depolymerization (GO:0007019)2.37821050
88DNA damage response, detection of DNA damage (GO:0042769)2.36208132
89regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.36096511
90exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.35989051
91replication fork processing (GO:0031297)2.35145393
92Sertoli cell development (GO:0060009)2.34312398
93G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.33824142
94acrosome reaction (GO:0007340)2.32945405
95cerebral cortex cell migration (GO:0021795)2.32633107
96neural tube formation (GO:0001841)2.32397584
97reflex (GO:0060004)2.30676107
98central nervous system neuron axonogenesis (GO:0021955)2.30178114
99regulation of development, heterochronic (GO:0040034)2.30045857
100regulation of timing of cell differentiation (GO:0048505)2.28707949

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.24853485
2EZH2_22144423_ChIP-Seq_EOC_Human3.39015683
3GBX2_23144817_ChIP-Seq_PC3_Human3.24870787
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.15607874
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.93956727
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.91899852
7ZNF274_21170338_ChIP-Seq_K562_Hela2.75003352
8FUS_26573619_Chip-Seq_HEK293_Human2.67239363
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.53877397
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.39346692
11IGF1R_20145208_ChIP-Seq_DFB_Human2.33314196
12CTBP2_25329375_ChIP-Seq_LNCAP_Human2.26556026
13VDR_22108803_ChIP-Seq_LS180_Human2.25414811
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.23495208
15EWS_26573619_Chip-Seq_HEK293_Human2.21154533
16TAF15_26573619_Chip-Seq_HEK293_Human2.19629660
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.17021706
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.14242790
19P300_19829295_ChIP-Seq_ESCs_Human2.11693815
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.07984317
21POU5F1_16153702_ChIP-ChIP_HESCs_Human1.99805641
22PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.92277217
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.89117145
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.88696793
25TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.83338146
26POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.83338146
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77317085
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.76960349
29REST_21632747_ChIP-Seq_MESCs_Mouse1.70634511
30RNF2_27304074_Chip-Seq_NSC_Mouse1.66407819
31PIAS1_25552417_ChIP-Seq_VCAP_Human1.60690367
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.58194435
33SMAD4_21799915_ChIP-Seq_A2780_Human1.57142429
34SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56762470
35AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56269430
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.55362097
37SMAD3_21741376_ChIP-Seq_EPCs_Human1.54499555
38BMI1_23680149_ChIP-Seq_NPCS_Mouse1.53563253
39SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.53019725
40UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.48139254
41MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.46838585
42HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.46545779
43SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45168545
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44349886
45STAT3_23295773_ChIP-Seq_U87_Human1.43015814
46JARID2_20064375_ChIP-Seq_MESCs_Mouse1.42442089
47TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40445247
48SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.39262403
49ER_23166858_ChIP-Seq_MCF-7_Human1.38730109
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.38179288
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37708098
52NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35881696
53SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.35825298
54FLI1_27457419_Chip-Seq_LIVER_Mouse1.35539811
55AR_25329375_ChIP-Seq_VCAP_Human1.33487914
56SOX2_16153702_ChIP-ChIP_HESCs_Human1.31136474
57SOX9_26525672_Chip-Seq_HEART_Mouse1.30807815
58RUNX2_22187159_ChIP-Seq_PCA_Human1.27357334
59BCAT_22108803_ChIP-Seq_LS180_Human1.26844771
60RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.22127825
61EZH2_27294783_Chip-Seq_ESCs_Mouse1.21546912
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.20724225
63TCF4_23295773_ChIP-Seq_U87_Human1.18904987
64TCF4_22108803_ChIP-Seq_LS180_Human1.18610074
65PCGF2_27294783_Chip-Seq_NPCs_Mouse1.17988112
66REST_18959480_ChIP-ChIP_MESCs_Mouse1.17716989
67GATA1_26923725_Chip-Seq_HPCs_Mouse1.16967693
68KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15966574
69EST1_17652178_ChIP-ChIP_JURKAT_Human1.14725642
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13313096
71SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.12712901
72MYC_18940864_ChIP-ChIP_HL60_Human1.12196397
73AR_21572438_ChIP-Seq_LNCaP_Human1.12018008
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11243701
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10662455
76CBP_20019798_ChIP-Seq_JUKART_Human1.10662455
77PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.09205369
78TBX3_20139965_ChIP-Seq_ESCs_Mouse1.09109109
79TBX3_20139965_ChIP-Seq_MESCs_Mouse1.08935861
80TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08470101
81FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.07657140
82TP63_19390658_ChIP-ChIP_HaCaT_Human1.06096204
83SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.05625107
84TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.05187580
85NANOG_19829295_ChIP-Seq_ESCs_Human1.04393340
86SOX2_19829295_ChIP-Seq_ESCs_Human1.04393340
87KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03544000
88EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03180183
89SOX2_21211035_ChIP-Seq_LN229_Gbm1.02111406
90NANOG_16153702_ChIP-ChIP_HESCs_Human1.01645757
91SUZ12_27294783_Chip-Seq_ESCs_Mouse1.00966307
92EZH2_18974828_ChIP-Seq_MESCs_Mouse1.00682433
93RNF2_18974828_ChIP-Seq_MESCs_Mouse1.00682433
94RNF2_27304074_Chip-Seq_ESCs_Mouse1.00549497
95IRF1_19129219_ChIP-ChIP_H3396_Human1.00107969
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99305845
97TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98713090
98STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.98478167
99SMAD3_21741376_ChIP-Seq_ESCs_Human0.97531518
100JARID2_20075857_ChIP-Seq_MESCs_Mouse0.96480853

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting4.97346311
2MP0003880_abnormal_central_pattern3.92284813
3MP0003787_abnormal_imprinting3.83819423
4MP0006292_abnormal_olfactory_placode3.42221548
5MP0003121_genomic_imprinting2.88180931
6MP0005423_abnormal_somatic_nervous2.42286618
7MP0004133_heterotaxia2.37365819
8MP0008877_abnormal_DNA_methylation2.32869833
9MP0001529_abnormal_vocalization2.29418508
10MP0008789_abnormal_olfactory_epithelium2.26887925
11MP0002938_white_spotting2.21230359
12MP0003136_yellow_coat_color2.10735514
13MP0001486_abnormal_startle_reflex2.05514286
14MP0000778_abnormal_nervous_system2.02489075
15MP0006276_abnormal_autonomic_nervous1.96273626
16MP0002736_abnormal_nociception_after1.90997240
17MP0000569_abnormal_digit_pigmentation1.82917949
18MP0001293_anophthalmia1.81455496
19MP0002653_abnormal_ependyma_morphology1.80112328
20MP0001968_abnormal_touch/_nociception1.79436879
21MP0005499_abnormal_olfactory_system1.75571037
22MP0005394_taste/olfaction_phenotype1.75571037
23MP0001984_abnormal_olfaction1.75055777
24MP0001485_abnormal_pinna_reflex1.65077469
25MP0000049_abnormal_middle_ear1.62540772
26MP0004742_abnormal_vestibular_system1.57296920
27MP0002233_abnormal_nose_morphology1.54873644
28MP0001188_hyperpigmentation1.49354254
29MP0004142_abnormal_muscle_tone1.47851712
30MP0000631_abnormal_neuroendocrine_gland1.45367443
31MP0005171_absent_coat_pigmentation1.45262284
32MP0002102_abnormal_ear_morphology1.44758218
33MP0002272_abnormal_nervous_system1.43400738
34MP0010030_abnormal_orbit_morphology1.42737124
35MP0002734_abnormal_mechanical_nocicepti1.42691781
36MP0009745_abnormal_behavioral_response1.40276235
37MP0003635_abnormal_synaptic_transmissio1.40010152
38MP0000566_synostosis1.39313589
39MP0008058_abnormal_DNA_repair1.35138770
40MP0003937_abnormal_limbs/digits/tail_de1.31191690
41MP0004859_abnormal_synaptic_plasticity1.31012135
42MP0002572_abnormal_emotion/affect_behav1.30573933
43MP0001286_abnormal_eye_development1.29197668
44MP0006072_abnormal_retinal_apoptosis1.27144847
45MP0002063_abnormal_learning/memory/cond1.26437079
46MP0003890_abnormal_embryonic-extraembry1.25302162
47MP0004885_abnormal_endolymph1.24698351
48MP0005377_hearing/vestibular/ear_phenot1.19928489
49MP0003878_abnormal_ear_physiology1.19928489
50MP0009046_muscle_twitch1.19226496
51MP0002067_abnormal_sensory_capabilities1.18671346
52MP0002184_abnormal_innervation1.18118212
53MP0003938_abnormal_ear_development1.18101802
54MP0002557_abnormal_social/conspecific_i1.18037994
55MP0002064_seizures1.18010375
56MP0002234_abnormal_pharynx_morphology1.13688222
57MP0003755_abnormal_palate_morphology1.13058343
58MP0004270_analgesia1.12679000
59MP0002735_abnormal_chemical_nociception1.11981283
60MP0009379_abnormal_foot_pigmentation1.11761170
61MP0005551_abnormal_eye_electrophysiolog1.05540391
62MP0002697_abnormal_eye_size1.05079893
63MP0000955_abnormal_spinal_cord1.04797955
64MP0000647_abnormal_sebaceous_gland1.04469513
65MP0002249_abnormal_larynx_morphology1.04141110
66MP0002928_abnormal_bile_duct1.02624373
67MP0000026_abnormal_inner_ear1.01710541
68MP0003861_abnormal_nervous_system1.01059469
69MP0005646_abnormal_pituitary_gland0.99823784
70MP0001970_abnormal_pain_threshold0.98117906
71MP0002152_abnormal_brain_morphology0.97190891
72MP0002752_abnormal_somatic_nervous0.96165638
73MP0005248_abnormal_Harderian_gland0.94925991
74MP0005187_abnormal_penis_morphology0.93504229
75MP0001440_abnormal_grooming_behavior0.92218046
76MP0001299_abnormal_eye_distance/0.91301162
77MP0005084_abnormal_gallbladder_morpholo0.90480551
78MP0003137_abnormal_impulse_conducting0.90472135
79MP0002882_abnormal_neuron_morphology0.90255530
80MP0005253_abnormal_eye_physiology0.89306306
81MP0004858_abnormal_nervous_system0.89139359
82MP0002095_abnormal_skin_pigmentation0.88951885
83MP0005386_behavior/neurological_phenoty0.88499585
84MP0004924_abnormal_behavior0.88499585
85MP0002751_abnormal_autonomic_nervous0.88381588
86MP0008569_lethality_at_weaning0.86959746
87MP0001963_abnormal_hearing_physiology0.84665679
88MP0005195_abnormal_posterior_eye0.84413828
89MP0003941_abnormal_skin_development0.80754413
90MP0002822_catalepsy0.80672904
91MP0003119_abnormal_digestive_system0.79420164
92MP0004811_abnormal_neuron_physiology0.78645456
93MP0005391_vision/eye_phenotype0.76094443
94MP0001177_atelectasis0.75026495
95MP0001324_abnormal_eye_pigmentation0.74051130
96MP0002282_abnormal_trachea_morphology0.71830327
97MP0003942_abnormal_urinary_system0.71829706
98MP0000534_abnormal_ureter_morphology0.71782994
99MP0009703_decreased_birth_body0.71655243
100MP0002116_abnormal_craniofacial_bone0.70074705

Predicted human phenotypes

RankGene SetZ-score
1True hermaphroditism (HP:0010459)4.04059351
2Abnormality of the labia minora (HP:0012880)3.86445135
3Pancreatic fibrosis (HP:0100732)3.61505662
4Focal motor seizures (HP:0011153)3.41628694
5Hepatoblastoma (HP:0002884)3.37020798
6Gait imbalance (HP:0002141)3.31079781
7Pancreatic cysts (HP:0001737)3.28413392
8Colon cancer (HP:0003003)3.23506033
9Medial flaring of the eyebrow (HP:0010747)3.21259851
10Congenital primary aphakia (HP:0007707)3.13118806
11Abnormality of midbrain morphology (HP:0002418)3.06504215
12Molar tooth sign on MRI (HP:0002419)3.06504215
13Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.04485862
14Degeneration of the lateral corticospinal tracts (HP:0002314)3.04485862
15Nephrogenic diabetes insipidus (HP:0009806)2.94089267
16Genital tract atresia (HP:0001827)2.82232695
17Aplasia/Hypoplasia of the sternum (HP:0006714)2.79357031
18Vaginal atresia (HP:0000148)2.78036498
19Volvulus (HP:0002580)2.73502908
20Type II lissencephaly (HP:0007260)2.71897772
21Genetic anticipation (HP:0003743)2.68638601
22Abnormality of the corticospinal tract (HP:0002492)2.62884373
23Atonic seizures (HP:0010819)2.61788961
24Abnormality of the aortic arch (HP:0012303)2.56906554
25Poor coordination (HP:0002370)2.54564969
26Cystic liver disease (HP:0006706)2.47133684
27Nephronophthisis (HP:0000090)2.45958793
28Septo-optic dysplasia (HP:0100842)2.45854787
29Febrile seizures (HP:0002373)2.45092162
30Median cleft lip (HP:0000161)2.44153776
31Sclerocornea (HP:0000647)2.40937874
32Aplasia/Hypoplasia of the tongue (HP:0010295)2.40737689
33Anophthalmia (HP:0000528)2.37930199
34Bilateral microphthalmos (HP:0007633)2.32325594
35Medulloblastoma (HP:0002885)2.30164607
36Focal seizures (HP:0007359)2.26244018
37Glioma (HP:0009733)2.24872841
38Anencephaly (HP:0002323)2.23372568
39Specific learning disability (HP:0001328)2.22272180
40Urinary urgency (HP:0000012)2.20578384
41Intestinal atresia (HP:0011100)2.09816077
42Retinal dysplasia (HP:0007973)2.09809288
43Oligodactyly (hands) (HP:0001180)2.08568376
44Postaxial hand polydactyly (HP:0001162)2.07141934
45Oligodactyly (HP:0012165)2.06630973
46Dialeptic seizures (HP:0011146)2.06067853
47Lissencephaly (HP:0001339)2.05650660
48Postaxial foot polydactyly (HP:0001830)2.04587606
49Congenital sensorineural hearing impairment (HP:0008527)2.04029481
50Broad foot (HP:0001769)2.02193175
51Midline defect of the nose (HP:0004122)2.00860732
52Abnormality of the renal medulla (HP:0100957)1.98953876
53Abnormal ciliary motility (HP:0012262)1.96267414
54Supernumerary spleens (HP:0009799)1.95432551
55Progressive cerebellar ataxia (HP:0002073)1.94157745
56Chronic hepatic failure (HP:0100626)1.93886677
57Bifid tongue (HP:0010297)1.92857034
58Male pseudohermaphroditism (HP:0000037)1.92450908
59Myokymia (HP:0002411)1.91797903
60Neoplasm of the oral cavity (HP:0100649)1.90731656
61Preaxial hand polydactyly (HP:0001177)1.89864573
62Bile duct proliferation (HP:0001408)1.88841549
63Abnormal biliary tract physiology (HP:0012439)1.88841549
64Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.86482559
65Short 4th metacarpal (HP:0010044)1.86482559
66Scrotal hypoplasia (HP:0000046)1.86173882
67Impaired vibration sensation in the lower limbs (HP:0002166)1.86138476
68Abnormal number of erythroid precursors (HP:0012131)1.84764016
69Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.84231068
70Facial hemangioma (HP:0000329)1.84174390
71Abnormal respiratory epithelium morphology (HP:0012253)1.82721220
72Abnormal respiratory motile cilium morphology (HP:0005938)1.82721220
73Abnormal respiratory motile cilium physiology (HP:0012261)1.82620289
74Narrow forehead (HP:0000341)1.81088703
75Urinary bladder sphincter dysfunction (HP:0002839)1.81017627
76Hyperglycinemia (HP:0002154)1.80815685
77Occipital encephalocele (HP:0002085)1.79970087
78Abnormality of the 4th metacarpal (HP:0010012)1.79748913
79Labial hypoplasia (HP:0000066)1.78828636
80Drooling (HP:0002307)1.76973344
81Micropenis (HP:0000054)1.76861719
82Neoplasm of striated muscle (HP:0009728)1.76595684
83Renal hypoplasia (HP:0000089)1.76554311
84Optic nerve hypoplasia (HP:0000609)1.76519817
85Polyphagia (HP:0002591)1.75943973
86Absence seizures (HP:0002121)1.75448774
87Holoprosencephaly (HP:0001360)1.74823276
88Dandy-Walker malformation (HP:0001305)1.74565061
89High anterior hairline (HP:0009890)1.73533723
90Supernumerary bones of the axial skeleton (HP:0009144)1.73132160
91Gastrointestinal atresia (HP:0002589)1.71504396
92Short foot (HP:0001773)1.70755249
93Aplasia/Hypoplasia of the tibia (HP:0005772)1.68092918
94Tubulointerstitial nephritis (HP:0001970)1.67746170
95Status epilepticus (HP:0002133)1.66886405
96Hypothermia (HP:0002045)1.66808988
9711 pairs of ribs (HP:0000878)1.66154824
98Abnormality of the nasal septum (HP:0000419)1.65293075
99Bicornuate uterus (HP:0000813)1.63836265
100Decreased testicular size (HP:0008734)1.63682232

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK3.71162006
2TSSK63.60109918
3MAPK153.20961983
4TNIK3.20125532
5CASK3.09932508
6MAP4K23.07217650
7MARK13.02406547
8WNK32.93203951
9MKNK22.40087554
10TRIM282.27117538
11DYRK22.03626993
12MAPK131.97553842
13NUAK11.92907129
14PLK41.88578908
15MKNK11.86472275
16FRK1.80309571
17EPHA41.78988796
18NTRK31.69488487
19CDC71.59224155
20PINK11.49956644
21MAPKAPK51.36884244
22PASK1.31606833
23VRK11.24513122
24LATS11.21564680
25PLK21.20016975
26PAK31.16859810
27EPHB21.15025243
28NTRK21.10124983
29MAP3K41.09845163
30WEE11.09758800
31CDK31.07872013
32BCR1.07864743
33CSNK1G21.05511309
34STK38L1.04469767
35DYRK31.02857392
36MINK11.02460809
37PRKCG0.98687854
38ERN10.97795766
39KSR10.96198010
40SRPK10.94911292
41UHMK10.92625987
42TIE10.92166574
43EPHA30.91140605
44CDK190.91005142
45PLK30.90744617
46BMPR1B0.88586362
47STK110.86120518
48NLK0.85551309
49BCKDK0.84084291
50TYRO30.83317512
51CSNK1G10.83201958
52CAMK10.80530950
53INSRR0.80014979
54GRK10.79588287
55NME10.78584283
56MAP2K70.76633670
57OXSR10.74870622
58CSNK1G30.70842078
59CSNK1A1L0.70609936
60MAP3K70.70431898
61ERBB30.69936159
62DYRK1A0.69167387
63ADRBK20.69165038
64SGK20.64256727
65TAOK10.64062742
66ZAK0.64045972
67PKN10.62560813
68AKT30.59648386
69BRD40.57527004
70OBSCN0.56836806
71CAMK1G0.55127807
72CDK180.53938926
73CAMKK20.52426645
74CDK150.51503788
75PRKCE0.51330981
76CAMK2A0.51091496
77TAOK30.50298809
78TGFBR10.48857765
79DAPK20.48464570
80SGK2230.47939221
81SGK4940.47939221
82CAMK40.47820899
83CDK11A0.47124215
84ACVR1B0.46629540
85PRKACA0.46164182
86PLK10.45005022
87VRK20.43554025
88STK390.43053412
89CDK50.42960500
90NEK20.42649275
91PRKDC0.40935033
92FGFR10.40751796
93CSNK1E0.40422295
94DMPK0.40261702
95MAP3K20.39227752
96RPS6KB20.39060557
97TAF10.38691940
98PRKG10.38556697
99RAF10.35579496
100DYRK1B0.34931829

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.28602938
2Protein export_Homo sapiens_hsa030602.61296351
3Steroid biosynthesis_Homo sapiens_hsa001002.28158743
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26351885
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.05100726
6Ribosome_Homo sapiens_hsa030101.92796682
7Selenocompound metabolism_Homo sapiens_hsa004501.91840217
8Butanoate metabolism_Homo sapiens_hsa006501.88399070
9Basal cell carcinoma_Homo sapiens_hsa052171.87418146
10Cardiac muscle contraction_Homo sapiens_hsa042601.73511951
11Fanconi anemia pathway_Homo sapiens_hsa034601.68697169
12Basal transcription factors_Homo sapiens_hsa030221.68254827
13Nitrogen metabolism_Homo sapiens_hsa009101.67272271
14Propanoate metabolism_Homo sapiens_hsa006401.65778499
15Taste transduction_Homo sapiens_hsa047421.62338430
16Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.55534266
17RNA polymerase_Homo sapiens_hsa030201.53511247
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.52736174
19Oxidative phosphorylation_Homo sapiens_hsa001901.51949158
20Circadian entrainment_Homo sapiens_hsa047131.50895189
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50127510
22Hedgehog signaling pathway_Homo sapiens_hsa043401.49264234
23RNA degradation_Homo sapiens_hsa030181.48171316
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.42203683
25GABAergic synapse_Homo sapiens_hsa047271.41009209
26Morphine addiction_Homo sapiens_hsa050321.39904708
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.39466301
28Glutamatergic synapse_Homo sapiens_hsa047241.37595364
29Parkinsons disease_Homo sapiens_hsa050121.34058284
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.33952838
31Phototransduction_Homo sapiens_hsa047441.33192863
32Insulin secretion_Homo sapiens_hsa049111.31277348
33beta-Alanine metabolism_Homo sapiens_hsa004101.29198951
34Mismatch repair_Homo sapiens_hsa034301.24779793
35Huntingtons disease_Homo sapiens_hsa050161.24470429
36Homologous recombination_Homo sapiens_hsa034401.17615838
37One carbon pool by folate_Homo sapiens_hsa006701.16702776
38Olfactory transduction_Homo sapiens_hsa047401.13296309
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13190524
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11605999
41Spliceosome_Homo sapiens_hsa030401.10935421
42Serotonergic synapse_Homo sapiens_hsa047261.10774034
43Axon guidance_Homo sapiens_hsa043601.07786945
44Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.07059202
45Hippo signaling pathway_Homo sapiens_hsa043901.05263635
46Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.03547382
47Dopaminergic synapse_Homo sapiens_hsa047281.03249314
48Peroxisome_Homo sapiens_hsa041461.00910196
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.99219115
50TGF-beta signaling pathway_Homo sapiens_hsa043500.96297247
51Wnt signaling pathway_Homo sapiens_hsa043100.95969914
52Long-term depression_Homo sapiens_hsa047300.94170643
53DNA replication_Homo sapiens_hsa030300.93402675
54Amphetamine addiction_Homo sapiens_hsa050310.91207294
55Tryptophan metabolism_Homo sapiens_hsa003800.88360058
56Alzheimers disease_Homo sapiens_hsa050100.85138930
57RNA transport_Homo sapiens_hsa030130.84723277
58Salivary secretion_Homo sapiens_hsa049700.84358236
59Fatty acid metabolism_Homo sapiens_hsa012120.83129223
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.77639436
61Synaptic vesicle cycle_Homo sapiens_hsa047210.75397628
62Linoleic acid metabolism_Homo sapiens_hsa005910.73700069
63Collecting duct acid secretion_Homo sapiens_hsa049660.72452069
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71877646
65Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69904041
66Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.69882278
67Vitamin digestion and absorption_Homo sapiens_hsa049770.69672464
68Histidine metabolism_Homo sapiens_hsa003400.68657247
69Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.68427799
70Cholinergic synapse_Homo sapiens_hsa047250.67984988
71Pyruvate metabolism_Homo sapiens_hsa006200.67516211
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67063980
73Dorso-ventral axis formation_Homo sapiens_hsa043200.67051220
74Oxytocin signaling pathway_Homo sapiens_hsa049210.66652049
75Chemical carcinogenesis_Homo sapiens_hsa052040.66133149
76Ether lipid metabolism_Homo sapiens_hsa005650.65246630
77Purine metabolism_Homo sapiens_hsa002300.64575723
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64061774
79Glutathione metabolism_Homo sapiens_hsa004800.63819173
80Primary bile acid biosynthesis_Homo sapiens_hsa001200.63524433
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63240431
82Oocyte meiosis_Homo sapiens_hsa041140.63086930
83cAMP signaling pathway_Homo sapiens_hsa040240.62764746
84Cocaine addiction_Homo sapiens_hsa050300.62230327
85Non-homologous end-joining_Homo sapiens_hsa034500.61951718
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61781898
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60984215
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.59129929
89mRNA surveillance pathway_Homo sapiens_hsa030150.58952782
90Fatty acid elongation_Homo sapiens_hsa000620.56844835
91Melanogenesis_Homo sapiens_hsa049160.55335436
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.54971465
93Retinol metabolism_Homo sapiens_hsa008300.53666749
94Gastric acid secretion_Homo sapiens_hsa049710.53600776
95Fatty acid degradation_Homo sapiens_hsa000710.51679535
96Thyroid hormone synthesis_Homo sapiens_hsa049180.50471466
97Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50056685
98Tight junction_Homo sapiens_hsa045300.49963850
99Gap junction_Homo sapiens_hsa045400.48025223
100Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.47554915

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