ZNF672

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of erythrocyte differentiation (GO:0045647)5.10704438
2response to peptidoglycan (GO:0032494)4.40726696
3immunoglobulin mediated immune response (GO:0016064)4.23157324
4positive regulation of gamma-delta T cell activation (GO:0046645)4.02705856
5positive regulation by symbiont of host defense response (GO:0052509)3.84569031
6modulation by symbiont of host defense response (GO:0052031)3.84569031
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.84569031
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.84569031
9positive regulation by organism of defense response of other organism involved in symbiotic interact3.84569031
10modulation by symbiont of host immune response (GO:0052553)3.84569031
11neutrophil activation involved in immune response (GO:0002283)3.82703452
12detection of bacterium (GO:0016045)3.78753297
13antigen processing and presentation of endogenous antigen (GO:0019883)3.78450009
14antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.68605107
15detection of other organism (GO:0098543)3.65920841
16NIK/NF-kappaB signaling (GO:0038061)3.58668819
17response to muramyl dipeptide (GO:0032495)3.52356956
18antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.52180400
193-UTR-mediated mRNA stabilization (GO:0070935)3.33677880
20negative regulation of cell killing (GO:0031342)3.32099294
21negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.32099294
22negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.31071201
23negative regulation of cell size (GO:0045792)3.29844997
24macrophage activation involved in immune response (GO:0002281)3.28707748
25germinal center formation (GO:0002467)3.25172737
26type I interferon signaling pathway (GO:0060337)3.19605822
27cellular response to type I interferon (GO:0071357)3.19605822
28response to type I interferon (GO:0034340)3.17666467
29N-acetylneuraminate metabolic process (GO:0006054)3.02561335
30regulation of mast cell degranulation (GO:0043304)3.01266902
31regulation of gamma-delta T cell activation (GO:0046643)3.01172732
32B cell mediated immunity (GO:0019724)3.00856217
33regulation of necrotic cell death (GO:0010939)2.98324956
34negative regulation of necrotic cell death (GO:0060547)2.96739768
35positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.96540314
36cellular response to thyroid hormone stimulus (GO:0097067)2.96476308
37antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.96227785
38interferon-gamma-mediated signaling pathway (GO:0060333)2.95107129
39mannose metabolic process (GO:0006013)2.91465697
40Arp2/3 complex-mediated actin nucleation (GO:0034314)2.88561120
41response to host immune response (GO:0052572)2.87000290
42response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.87000290
43detection of external biotic stimulus (GO:0098581)2.86636635
44modulation by symbiont of host cellular process (GO:0044068)2.83684909
45negative regulation of interleukin-12 production (GO:0032695)2.83155275
46amino sugar catabolic process (GO:0046348)2.81766858
47negative regulation of necroptotic process (GO:0060546)2.80329555
48negative regulation of innate immune response (GO:0045824)2.77409477
49response to protozoan (GO:0001562)2.76440679
50defense response to protozoan (GO:0042832)2.76098995
51regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.75418614
52lipopolysaccharide-mediated signaling pathway (GO:0031663)2.74836559
53regulation of interferon-beta biosynthetic process (GO:0045357)2.74533060
54regulation of antigen processing and presentation (GO:0002577)2.73567866
55regulation of necroptotic process (GO:0060544)2.73496181
56regulation of dendritic cell antigen processing and presentation (GO:0002604)2.72905913
57B cell receptor signaling pathway (GO:0050853)2.72646853
58positive thymic T cell selection (GO:0045059)2.70535944
59regulation of skeletal muscle contraction (GO:0014819)2.70181002
60modulation by virus of host process (GO:0019054)2.68731075
61T-helper 1 type immune response (GO:0042088)2.67252239
62regulation of type I interferon-mediated signaling pathway (GO:0060338)2.65468998
63positive regulation of antigen processing and presentation (GO:0002579)2.62568185
64glycosphingolipid catabolic process (GO:0046479)2.61656885
65negative regulation of myeloid cell apoptotic process (GO:0033033)2.60987100
66regulation of cholesterol storage (GO:0010885)2.60925560
67positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.60788469
68cellular response to arsenic-containing substance (GO:0071243)2.59068275
69positive regulation of Cdc42 GTPase activity (GO:0043089)2.58795417
70creatine metabolic process (GO:0006600)2.58782928
71regulation of leukocyte degranulation (GO:0043300)2.58336748
72regulation of mast cell activation involved in immune response (GO:0033006)2.58034481
73response to host (GO:0075136)2.57293808
74response to host defenses (GO:0052200)2.57293808
75response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.57293808
76positive regulation of B cell differentiation (GO:0045579)2.57122129
77regulation of gamma-delta T cell differentiation (GO:0045586)2.56005970
78activation of MAPKKK activity (GO:0000185)2.55290128
79adenosine receptor signaling pathway (GO:0001973)2.54782393
80pentose-phosphate shunt (GO:0006098)2.54397769
81positive regulation of type 2 immune response (GO:0002830)2.51354855
82regulation of myeloid leukocyte mediated immunity (GO:0002886)2.51013158
83response to thyroid hormone (GO:0097066)2.50790090
84myeloid cell activation involved in immune response (GO:0002275)2.49865353
85myeloid dendritic cell differentiation (GO:0043011)2.49832165
86detection of biotic stimulus (GO:0009595)2.49143840
87mature B cell differentiation involved in immune response (GO:0002313)2.47925354
88G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.45988344
89regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.45695522
90chaperone mediated protein folding requiring cofactor (GO:0051085)2.45265225
91amyloid precursor protein catabolic process (GO:0042987)2.43186347
92granulocyte activation (GO:0036230)2.42249615
93regulation of interleukin-2 biosynthetic process (GO:0045076)2.41748869
94CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.41707823
95positive regulation of fatty acid biosynthetic process (GO:0045723)2.40922672
96negative regulation of cytokine production involved in immune response (GO:0002719)2.40620177
97positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.39686924
98G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.39250816
99cellular response to virus (GO:0098586)2.36496512
100intracellular estrogen receptor signaling pathway (GO:0030520)2.35618214

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1VDR_21846776_ChIP-Seq_THP-1_Human3.43139852
2MYC_22102868_ChIP-Seq_BL_Human2.92326868
3LXR_22292898_ChIP-Seq_THP-1_Human2.61127564
4IRF8_22096565_ChIP-ChIP_GC-B_Human2.44089786
5TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.37461353
6NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.19870041
7KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.18648837
8* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.13723922
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.10644274
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.10459374
11* ELK3_25401928_ChIP-Seq_HUVEC_Human2.08097602
12* MAF_26560356_Chip-Seq_TH1_Human2.06658527
13* VDR_24763502_ChIP-Seq_THP-1_Human2.03821351
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.99223706
15TCF7_22412390_ChIP-Seq_EML_Mouse1.97239701
16KDM2B_26808549_Chip-Seq_DND41_Human1.97209901
17E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.96470625
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.82914009
19MAF_26560356_Chip-Seq_TH2_Human1.81782159
20RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.81291842
21EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.79776602
22UTX_26944678_Chip-Seq_JUKART_Human1.78578641
23P68_20966046_ChIP-Seq_HELA_Human1.78471946
24SCL_19346495_ChIP-Seq_HPC-7_Human1.75583496
25PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.75141920
26RACK7_27058665_Chip-Seq_MCF-7_Human1.73638825
27BCL6_27268052_Chip-Seq_Bcells_Human1.66517429
28ELF1_20517297_ChIP-Seq_JURKAT_Human1.65513718
29TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65028253
30NCOR1_26117541_ChIP-Seq_K562_Human1.63600035
31IRF8_21731497_ChIP-ChIP_J774_Mouse1.62472780
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.62284665
33MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.58099819
34BCOR_27268052_Chip-Seq_Bcells_Human1.57853081
35CTCF_27219007_Chip-Seq_ERYTHROID_Human1.54516293
36SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.53453362
37KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.52196173
38NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.50801884
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.50374756
40GATA1_22383799_ChIP-Seq_G1ME_Mouse1.49916981
41SA1_27219007_Chip-Seq_ERYTHROID_Human1.49865922
42GATA1_19941827_ChIP-Seq_MEL_Mouse1.46462348
43TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.46193398
44TET1_21451524_ChIP-Seq_MESCs_Mouse1.46159480
45SRY_22984422_ChIP-ChIP_TESTIS_Rat1.44242395
46DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.43493831
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43249263
48* SPI1_23547873_ChIP-Seq_NB4_Human1.41782358
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41417610
50RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41180781
51STAT4_19710469_ChIP-ChIP_TH1__Mouse1.40252414
52SPI1_23127762_ChIP-Seq_K562_Human1.38996768
53CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.38775406
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.38537634
55PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.38102619
56* CIITA_25753668_ChIP-Seq_RAJI_Human1.37675551
57PU.1_20513432_ChIP-Seq_Bcells_Mouse1.34031892
58SMC4_20622854_ChIP-Seq_HELA_Human1.33560380
59EGR1_19374776_ChIP-ChIP_THP-1_Human1.32503632
60GATA1_19941826_ChIP-Seq_K562_Human1.30626083
61NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.30377126
62STAT6_21828071_ChIP-Seq_BEAS2B_Human1.30319915
63SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.27183699
64KDM2B_26808549_Chip-Seq_K562_Human1.25873908
65CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.24380898
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23118687
67HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.21085230
68CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.19886086
69CTCF_21964334_ChIP-Seq_BJAB-B_Human1.19311406
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.18694571
71IRF8_27001747_Chip-Seq_BMDM_Mouse1.18221797
72RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.17959683
73ZNF263_19887448_ChIP-Seq_K562_Human1.16842303
74* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16241527
75LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.16142479
76GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16055513
77CTCF_21964334_Chip-Seq_Bcells_Human1.15997298
78CTCF_26484167_Chip-Seq_Bcells_Mouse1.14957635
79E2F1_20622854_ChIP-Seq_HELA_Human1.14614407
80PHF8_20622854_ChIP-Seq_HELA_Human1.14407964
81SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14125161
82SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.13793557
83VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.13574704
84MYB_21317192_ChIP-Seq_ERMYB_Mouse1.13106023
85CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12855003
86KDM2B_26808549_Chip-Seq_JURKAT_Human1.12833729
87GATA1_22025678_ChIP-Seq_K562_Human1.12067933
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.10801301
89SA1_27219007_Chip-Seq_Bcells_Human1.10092333
90YY1_22570637_ChIP-Seq_MALME-3M_Human1.09915797
91PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09185095
92ELF1_17652178_ChIP-ChIP_JURKAT_Human1.08756348
93DNAJC2_21179169_ChIP-ChIP_NT2_Human1.07774992
94IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.07281383
95* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.06562280
96CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06431311
97TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06110023
98GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.05787807
99SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04670804
100BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04436256

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation4.10284839
2MP0005451_abnormal_body_composition3.92639348
3MP0009278_abnormal_bone_marrow3.61766308
4MP0009840_abnormal_foam_cell3.40157239
5MP0005058_abnormal_lysosome_morphology3.39974943
6MP0003436_decreased_susceptibility_to3.12745507
7MP0001835_abnormal_antigen_presentation2.51484234
8MP0005397_hematopoietic_system_phenotyp2.47917216
9MP0001545_abnormal_hematopoietic_system2.47917216
10MP0003191_abnormal_cellular_cholesterol2.44868047
11MP0008260_abnormal_autophagy2.34094067
12MP0005464_abnormal_platelet_physiology2.31713547
13MP0001790_abnormal_immune_system2.29062327
14MP0005387_immune_system_phenotype2.29062327
15MP0005025_abnormal_response_to2.25967704
16MP0003724_increased_susceptibility_to2.21471570
17MP0000685_abnormal_immune_system2.16814017
18MP0005000_abnormal_immune_tolerance2.14490916
19MP0002419_abnormal_innate_immunity2.10224286
20MP0003172_abnormal_lysosome_physiology2.09167428
21MP0003806_abnormal_nucleotide_metabolis2.04473025
22MP0002148_abnormal_hypersensitivity_rea2.02361600
23MP0009785_altered_susceptibility_to2.00606284
24MP0003656_abnormal_erythrocyte_physiolo1.99771520
25MP0001800_abnormal_humoral_immune1.98691036
26MP0009333_abnormal_splenocyte_physiolog1.98200151
27MP0002723_abnormal_immune_serum1.90271632
28MP0002452_abnormal_antigen_presenting1.88971453
29MP0004510_myositis1.79450627
30MP0003300_gastrointestinal_ulcer1.77464296
31MP0002420_abnormal_adaptive_immunity1.76877093
32MP0001819_abnormal_immune_cell1.75537904
33MP0005671_abnormal_response_to1.70689695
34MP0004947_skin_inflammation1.68399042
35MP0002398_abnormal_bone_marrow1.60505470
36MP0000465_gastrointestinal_hemorrhage1.58308156
37MP0003763_abnormal_thymus_physiology1.52408686
38MP0010155_abnormal_intestine_physiology1.51154163
39MP0003646_muscle_fatigue1.49239255
40MP0005083_abnormal_biliary_tract1.47723576
41MP0000716_abnormal_immune_system1.46694550
42MP0000858_altered_metastatic_potential1.45699804
43MP0000751_myopathy1.44684343
44MP0008004_abnormal_stomach_pH1.43069650
45MP0000343_altered_response_to1.37773822
46MP0002429_abnormal_blood_cell1.35691995
47MP0001845_abnormal_inflammatory_respons1.34191639
48MP0009764_decreased_sensitivity_to1.32950652
49MP0002132_abnormal_respiratory_system1.32297648
50MP0003183_abnormal_peptide_metabolism1.32278739
51MP0000747_muscle_weakness1.28517383
52MP0000689_abnormal_spleen_morphology1.28378021
53MP0002722_abnormal_immune_system1.27745011
54MP0000750_abnormal_muscle_regeneration1.26628525
55MP0003453_abnormal_keratinocyte_physiol1.26091743
56MP0002139_abnormal_hepatobiliary_system1.23292721
57MP0002653_abnormal_ependyma_morphology1.22748694
58MP0008469_abnormal_protein_level1.22373298
59MP0001533_abnormal_skeleton_physiology1.21373377
60MP0003075_altered_response_to1.18941189
61MP0002405_respiratory_system_inflammati1.18647500
62MP0006082_CNS_inflammation1.15270794
63MP0000490_abnormal_crypts_of1.12474782
64MP0001873_stomach_inflammation1.09812692
65MP0003221_abnormal_cardiomyocyte_apopto1.09288058
66MP0002332_abnormal_exercise_endurance1.08794093
67MP0005666_abnormal_adipose_tissue1.05612921
68MP0000604_amyloidosis1.02842209
69MP0004233_abnormal_muscle_weight1.02189999
70MP0000678_abnormal_parathyroid_gland1.01634356
71MP0000015_abnormal_ear_pigmentation0.99955216
72MP0005076_abnormal_cell_differentiation0.95757666
73MP0000703_abnormal_thymus_morphology0.94309252
74MP0001853_heart_inflammation0.93366500
75MP0004185_abnormal_adipocyte_glucose0.92823034
76MP0006036_abnormal_mitochondrial_physio0.91993360
77MP0004130_abnormal_muscle_cell0.90812217
78MP0005584_abnormal_enzyme/coenzyme_acti0.82751245
79MP0000759_abnormal_skeletal_muscle0.82693804
80MP0005166_decreased_susceptibility_to0.81317033
81MP0008874_decreased_physiological_sensi0.78798802
82MP0002106_abnormal_muscle_physiology0.78428176
83MP0000609_abnormal_liver_physiology0.77243665
84MP0001986_abnormal_taste_sensitivity0.76973830
85MP0001663_abnormal_digestive_system0.76672338
86MP0000681_abnormal_thyroid_gland0.76036336
87MP0004381_abnormal_hair_follicle0.75178989
88MP0003329_amyloid_beta_deposits0.74930265
89MP0002998_abnormal_bone_remodeling0.74041019
90MP0001849_ear_inflammation0.73414445
91MP0009763_increased_sensitivity_to0.71308059
92MP0009931_abnormal_skin_appearance0.71074380
93MP0002019_abnormal_tumor_incidence0.70606711
94MP0004858_abnormal_nervous_system0.70124880
95MP0005330_cardiomyopathy0.69398094
96MP0004087_abnormal_muscle_fiber0.69285255
97MP0001851_eye_inflammation0.66895292
98MP0005319_abnormal_enzyme/_coenzyme0.66298281
99MP0005501_abnormal_skin_physiology0.66273977
100MP0009765_abnormal_xenobiotic_induced0.66256700

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced myalgia (HP:0003738)4.01848116
2Myopathic facies (HP:0002058)3.97511740
3Eczematoid dermatitis (HP:0000976)3.92908173
4Abnormality of macrophages (HP:0004311)3.49111401
5Petechiae (HP:0000967)3.40081560
6Centrally nucleated skeletal muscle fibers (HP:0003687)3.32605550
7Recurrent abscess formation (HP:0002722)3.25426841
8Ragged-red muscle fibers (HP:0003200)3.24757194
9Hypertensive crisis (HP:0100735)3.18537249
10Recurrent bacterial skin infections (HP:0005406)3.15534668
11Colitis (HP:0002583)3.12561061
12Obstructive lung disease (HP:0006536)3.11494141
13Chronic obstructive pulmonary disease (HP:0006510)3.11494141
14Mediastinal lymphadenopathy (HP:0100721)3.10748788
15Rhabdomyolysis (HP:0003201)3.07092195
16Abnormality of liposaccharide metabolism (HP:0010968)3.05703717
17Abnormality of glycosphingolipid metabolism (HP:0004343)3.05703717
18Abnormality of glycolipid metabolism (HP:0010969)3.05703717
19Purpura (HP:0000979)3.03241335
20Increased serum ferritin (HP:0003281)2.97072386
21Increased cerebral lipofuscin (HP:0011813)2.92232113
22Increased IgE level (HP:0003212)2.84884102
23Systemic lupus erythematosus (HP:0002725)2.83657933
24Reticulocytosis (HP:0001923)2.81265719
25Cellulitis (HP:0100658)2.78112910
26Prolonged bleeding time (HP:0003010)2.71424502
27Abnormal gallbladder physiology (HP:0012438)2.68294600
28Cholecystitis (HP:0001082)2.68294600
29Abnormality of the heme biosynthetic pathway (HP:0010472)2.66482238
30Loss of speech (HP:0002371)2.65747762
31Polycythemia (HP:0001901)2.63439454
32Gastrointestinal inflammation (HP:0004386)2.61100649
33Myositis (HP:0100614)2.59918612
34Myoglobinuria (HP:0002913)2.57079263
35Recurrent fungal infections (HP:0002841)2.55830231
36Distal lower limb muscle weakness (HP:0009053)2.54242793
37Muscle fiber inclusion bodies (HP:0100299)2.52984297
38Meningitis (HP:0001287)2.49388461
39Abnormality of iron homeostasis (HP:0011031)2.46526497
40Increased neuronal autofluorescent lipopigment (HP:0002074)2.46121503
41Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.45212033
42Recurrent viral infections (HP:0004429)2.42661057
43Recurrent gram-negative bacterial infections (HP:0005420)2.40367770
44Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.39780181
45Agammaglobulinemia (HP:0004432)2.39322929
46Nemaline bodies (HP:0003798)2.38809440
47Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.37826284
48Inflammation of the large intestine (HP:0002037)2.36804256
49Distal lower limb amyotrophy (HP:0008944)2.35613907
50Stomatitis (HP:0010280)2.34881996
51Dysostosis multiplex (HP:0000943)2.31004316
52Urticaria (HP:0001025)2.30820882
53Orchitis (HP:0100796)2.29638549
54Epistaxis (HP:0000421)2.26530679
55Gastrointestinal stroma tumor (HP:0100723)2.25147773
56Hemorrhage of the eye (HP:0011885)2.24400957
57Bulbar palsy (HP:0001283)2.24026939
58Asymmetric septal hypertrophy (HP:0001670)2.24012709
59Cholelithiasis (HP:0001081)2.23097121
60Progressive muscle weakness (HP:0003323)2.22347657
61Fatigue (HP:0012378)2.21994899
62Increased connective tissue (HP:0009025)2.15637894
63Increased IgM level (HP:0003496)2.15152472
64Abnormality of skeletal muscle fiber size (HP:0012084)2.13436930
65Vacuolated lymphocytes (HP:0001922)2.13133818
66Elevated erythrocyte sedimentation rate (HP:0003565)2.09394436
67Recurrent skin infections (HP:0001581)2.08007214
68Increased muscle lipid content (HP:0009058)2.05865423
69Chest pain (HP:0100749)2.05497459
70Spontaneous hematomas (HP:0007420)2.03752161
71Neuronal loss in central nervous system (HP:0002529)2.03553381
72Gastrointestinal infarctions (HP:0005244)2.02887508
73Hyperthyroidism (HP:0000836)2.02041921
74EMG: myopathic abnormalities (HP:0003458)2.00709169
75Chronic mucocutaneous candidiasis (HP:0002728)2.00414802
76Recurrent cutaneous fungal infections (HP:0011370)2.00414802
77Abnormality of reticulocytes (HP:0004312)2.00009300
78Hyperacusis (HP:0010780)1.99115429
79Vasculitis (HP:0002633)1.97596656
80Hepatosplenomegaly (HP:0001433)1.95563376
81Diaphragmatic weakness (HP:0009113)1.95154305
82Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.93549906
83Progressive external ophthalmoplegia (HP:0000590)1.92594220
84Pustule (HP:0200039)1.88765974
85Upper motor neuron abnormality (HP:0002127)1.87435362
86Thrombocytosis (HP:0001894)1.86659488
87Abnormal platelet function (HP:0011869)1.84971652
88Impaired platelet aggregation (HP:0003540)1.84971652
89Osteomyelitis (HP:0002754)1.84930770
90Muscle stiffness (HP:0003552)1.84540473
91Increased variability in muscle fiber diameter (HP:0003557)1.84251887
92Interstitial pulmonary disease (HP:0006530)1.84037069
93Retrobulbar optic neuritis (HP:0100654)1.83890121
94Optic neuritis (HP:0100653)1.83890121
95Increased intramyocellular lipid droplets (HP:0012240)1.83309796
96Gastrointestinal dysmotility (HP:0002579)1.83299964
97Gingivitis (HP:0000230)1.82697103
98Rimmed vacuoles (HP:0003805)1.82651539
99Abnormal gallbladder morphology (HP:0012437)1.82507267
100Encephalitis (HP:0002383)1.81950126

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.93339293
2ERN13.63741539
3PRPF4B3.52308465
4MAP3K113.23199762
5MAP2K32.67336495
6TRIB32.49596202
7SMG12.49583036
8RIPK42.44315424
9IRAK32.42956802
10NME22.34642348
11ICK2.13395858
12TBK12.02796728
13IRAK41.94166053
14TAOK21.93280141
15TESK21.91549189
16BLK1.91053104
17TTN1.84371605
18TYK21.80677121
19MAP3K141.56535112
20MAP3K131.52528841
21SIK11.45525028
22BTK1.43642834
23EPHB11.42917560
24MAP3K11.42852792
25DYRK1B1.40968034
26SIK21.40611723
27JAK31.39603718
28ZAP701.39536623
29EEF2K1.35189368
30PIM21.29068010
31SIK31.25739773
32MATK1.24839837
33TAOK11.23010869
34OBSCN1.21080191
35MAP3K31.19523338
36FGR1.07934129
37CDK191.06361350
38BMX1.04774166
39SYK1.03714359
40PRKD21.02339047
41TNK21.01312281
42IKBKB1.01144379
43MARK20.99626760
44CSK0.99383586
45MAPK120.96660320
46GRK60.90609551
47KSR20.90602060
48MAPK110.87477497
49HCK0.84975974
50CSF1R0.84909222
51MAP2K60.83449534
52MAP3K60.83110055
53PDPK10.79808790
54MAP3K100.78515212
55RIPK10.77704949
56ARAF0.77244413
57FGFR40.75922562
58RPS6KC10.75653036
59RPS6KL10.75653036
60MARK30.75127333
61CDK40.74678090
62HIPK20.71627763
63IKBKE0.71399181
64JAK20.70738909
65PKN20.70535940
66LYN0.69308274
67PTK60.68653208
68MAP2K40.68362761
69CDC42BPA0.65996211
70MAP3K70.65979668
71LRRK20.65613628
72BCKDK0.65165204
73IRAK20.64995224
74FES0.60980174
75CDK60.58288118
76RPS6KA20.57303838
77RPS6KA60.56749308
78MAP2K20.56000585
79PDK10.53862251
80MAPKAPK30.50784245
81MAP3K50.48985304
82LCK0.47413297
83PIM10.47412323
84SCYL20.44169444
85MTOR0.43408082
86MAP3K80.42838740
87TESK10.41898658
88DDR20.40315297
89BRAF0.40083160
90DYRK30.40031853
91TAOK30.38635724
92MAPK40.37724270
93TYRO30.37556501
94RPS6KA10.37527476
95CDK120.36068276
96PRKD10.33977590
97PAK40.32963723
98CHUK0.30346138
99KIT0.30205224
100AKT20.29999671

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005113.16641164
2Leishmaniasis_Homo sapiens_hsa051402.62419641
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.57760361
4Allograft rejection_Homo sapiens_hsa053302.54080889
5Staphylococcus aureus infection_Homo sapiens_hsa051502.38183403
6Asthma_Homo sapiens_hsa053102.30606520
7Autoimmune thyroid disease_Homo sapiens_hsa053202.27819813
8Fructose and mannose metabolism_Homo sapiens_hsa000512.21658239
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.20404471
10Osteoclast differentiation_Homo sapiens_hsa043802.18114091
11Graft-versus-host disease_Homo sapiens_hsa053322.11381104
12Pentose phosphate pathway_Homo sapiens_hsa000302.04628584
13B cell receptor signaling pathway_Homo sapiens_hsa046621.97275055
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.95317382
15Viral myocarditis_Homo sapiens_hsa054161.86752021
16Tuberculosis_Homo sapiens_hsa051521.85979539
17Acute myeloid leukemia_Homo sapiens_hsa052211.71795594
18Primary immunodeficiency_Homo sapiens_hsa053401.69177809
19Type I diabetes mellitus_Homo sapiens_hsa049401.65409558
20Influenza A_Homo sapiens_hsa051641.61568239
21Lysosome_Homo sapiens_hsa041421.60419488
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.54571207
23Herpes simplex infection_Homo sapiens_hsa051681.53728445
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.52861334
25Toxoplasmosis_Homo sapiens_hsa051451.46944166
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.46785334
27Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.43604580
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.40503938
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.39991092
30Antigen processing and presentation_Homo sapiens_hsa046121.34661660
31Galactose metabolism_Homo sapiens_hsa000521.29331963
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.28175028
33Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.26365800
34Rheumatoid arthritis_Homo sapiens_hsa053231.15016238
35VEGF signaling pathway_Homo sapiens_hsa043701.14747064
36Biosynthesis of amino acids_Homo sapiens_hsa012301.14744293
37Phagosome_Homo sapiens_hsa041451.13908693
38Salmonella infection_Homo sapiens_hsa051321.13148551
39Notch signaling pathway_Homo sapiens_hsa043301.12639672
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.12529868
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.12455143
42Bladder cancer_Homo sapiens_hsa052191.10787221
43Hematopoietic cell lineage_Homo sapiens_hsa046401.09896051
44TNF signaling pathway_Homo sapiens_hsa046681.09068562
45Systemic lupus erythematosus_Homo sapiens_hsa053221.06665113
46Shigellosis_Homo sapiens_hsa051311.05708263
47Hepatitis B_Homo sapiens_hsa051611.05693863
48Pertussis_Homo sapiens_hsa051331.03611067
49Carbon metabolism_Homo sapiens_hsa012001.03463726
50Chronic myeloid leukemia_Homo sapiens_hsa052201.03268918
51Malaria_Homo sapiens_hsa051441.02134058
52Sulfur relay system_Homo sapiens_hsa041221.01958374
53Apoptosis_Homo sapiens_hsa042101.01203297
54Hepatitis C_Homo sapiens_hsa051601.00501806
55Measles_Homo sapiens_hsa051620.99436724
56Non-small cell lung cancer_Homo sapiens_hsa052230.94063767
57NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93702479
58Legionellosis_Homo sapiens_hsa051340.93518279
59Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.92054426
60Base excision repair_Homo sapiens_hsa034100.90861122
61Chemokine signaling pathway_Homo sapiens_hsa040620.89316528
62Epstein-Barr virus infection_Homo sapiens_hsa051690.88432170
63Adipocytokine signaling pathway_Homo sapiens_hsa049200.87840959
64Pancreatic cancer_Homo sapiens_hsa052120.82888070
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.82732024
66Insulin resistance_Homo sapiens_hsa049310.80988893
67Viral carcinogenesis_Homo sapiens_hsa052030.79537705
68Insulin signaling pathway_Homo sapiens_hsa049100.77413848
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76474518
70Jak-STAT signaling pathway_Homo sapiens_hsa046300.73715576
71Platelet activation_Homo sapiens_hsa046110.72472322
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.69638953
73HTLV-I infection_Homo sapiens_hsa051660.68644097
74Central carbon metabolism in cancer_Homo sapiens_hsa052300.65540228
75T cell receptor signaling pathway_Homo sapiens_hsa046600.61447683
76Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60503375
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59324918
78Prion diseases_Homo sapiens_hsa050200.56695041
79Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.56350746
80Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55873787
81Prolactin signaling pathway_Homo sapiens_hsa049170.55006402
82Endocytosis_Homo sapiens_hsa041440.54632822
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54397263
84Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53169273
85HIF-1 signaling pathway_Homo sapiens_hsa040660.52460456
86mTOR signaling pathway_Homo sapiens_hsa041500.51974608
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51358237
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50646002
89Glycerophospholipid metabolism_Homo sapiens_hsa005640.50154887
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.47172044
91Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43963624
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.42855313
93Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42045037
94AMPK signaling pathway_Homo sapiens_hsa041520.37320940
95SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37159265
96Renal cell carcinoma_Homo sapiens_hsa052110.36353871
97Arginine biosynthesis_Homo sapiens_hsa002200.34924091
98Inositol phosphate metabolism_Homo sapiens_hsa005620.33794062
99African trypanosomiasis_Homo sapiens_hsa051430.33502145
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33372039

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »