

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.23945769 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.58912309 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.58912309 |
| 4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.57036109 |
| 5 | respiratory electron transport chain (GO:0022904) | 5.16971125 |
| 6 | electron transport chain (GO:0022900) | 5.07355134 |
| 7 | protein complex biogenesis (GO:0070271) | 4.76702840 |
| 8 | proteasome assembly (GO:0043248) | 4.64501797 |
| 9 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.60425926 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.60425926 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.60425926 |
| 12 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.41495578 |
| 13 | oxidative phosphorylation (GO:0006119) | 3.82446589 |
| 14 | respiratory chain complex IV assembly (GO:0008535) | 3.80536564 |
| 15 | protein neddylation (GO:0045116) | 3.80319363 |
| 16 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.72806816 |
| 17 | cytochrome complex assembly (GO:0017004) | 3.70310503 |
| 18 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.69230321 |
| 19 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.69230321 |
| 20 | hydrogen ion transmembrane transport (GO:1902600) | 3.59284588 |
| 21 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.52251607 |
| 22 | chaperone-mediated protein transport (GO:0072321) | 3.50036288 |
| 23 | rRNA modification (GO:0000154) | 3.48266572 |
| 24 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.47165302 |
| 25 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.43980340 |
| 26 | platelet dense granule organization (GO:0060155) | 3.42777478 |
| 27 | cotranslational protein targeting to membrane (GO:0006613) | 3.42671703 |
| 28 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.41677065 |
| 29 | termination of RNA polymerase III transcription (GO:0006386) | 3.41677065 |
| 30 | protein targeting to ER (GO:0045047) | 3.39371313 |
| 31 | ribosomal small subunit assembly (GO:0000028) | 3.36624792 |
| 32 | DNA deamination (GO:0045006) | 3.34844531 |
| 33 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.33817281 |
| 34 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.32976541 |
| 35 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.32054801 |
| 36 | protein localization to endoplasmic reticulum (GO:0070972) | 3.31749128 |
| 37 | ATP biosynthetic process (GO:0006754) | 3.29688013 |
| 38 | protein-cofactor linkage (GO:0018065) | 3.29522842 |
| 39 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.28429877 |
| 40 | proton transport (GO:0015992) | 3.28388065 |
| 41 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.24707223 |
| 42 | viral transcription (GO:0019083) | 3.23355156 |
| 43 | hydrogen transport (GO:0006818) | 3.23030920 |
| 44 | protein targeting to mitochondrion (GO:0006626) | 3.22941387 |
| 45 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.22610570 |
| 46 | cullin deneddylation (GO:0010388) | 3.20476158 |
| 47 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.19840928 |
| 48 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.17469677 |
| 49 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.17469677 |
| 50 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.17464107 |
| 51 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.17352379 |
| 52 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.17352379 |
| 53 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.17352379 |
| 54 | ribosomal large subunit biogenesis (GO:0042273) | 3.16741428 |
| 55 | translational termination (GO:0006415) | 3.15406172 |
| 56 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.14577766 |
| 57 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.06941477 |
| 58 | protein localization to mitochondrion (GO:0070585) | 3.06222262 |
| 59 | establishment of protein localization to mitochondrion (GO:0072655) | 3.03225175 |
| 60 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.03089766 |
| 61 | regulation of mitochondrial translation (GO:0070129) | 3.01516009 |
| 62 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.00121390 |
| 63 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.00089201 |
| 64 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.00089201 |
| 65 | mannosylation (GO:0097502) | 2.99604232 |
| 66 | positive regulation of mitochondrial fission (GO:0090141) | 2.99364572 |
| 67 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.99282651 |
| 68 | organelle disassembly (GO:1903008) | 2.96330726 |
| 69 | translation (GO:0006412) | 2.95305877 |
| 70 | purine nucleotide salvage (GO:0032261) | 2.93703516 |
| 71 | GPI anchor biosynthetic process (GO:0006506) | 2.93697484 |
| 72 | negative regulation of ligase activity (GO:0051352) | 2.93615174 |
| 73 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.93615174 |
| 74 | aerobic respiration (GO:0009060) | 2.87472730 |
| 75 | GPI anchor metabolic process (GO:0006505) | 2.82798497 |
| 76 | C-terminal protein lipidation (GO:0006501) | 2.80531118 |
| 77 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.80127634 |
| 78 | rRNA methylation (GO:0031167) | 2.79355952 |
| 79 | translational elongation (GO:0006414) | 2.77943100 |
| 80 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.76497402 |
| 81 | protein deneddylation (GO:0000338) | 2.75194301 |
| 82 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.74651052 |
| 83 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.73616807 |
| 84 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.73616807 |
| 85 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.72102522 |
| 86 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.72102522 |
| 87 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.71817134 |
| 88 | positive regulation of ligase activity (GO:0051351) | 2.69435596 |
| 89 | anterograde synaptic vesicle transport (GO:0048490) | 2.67593155 |
| 90 | GTP biosynthetic process (GO:0006183) | 2.66728649 |
| 91 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.65407008 |
| 92 | ribonucleoprotein complex disassembly (GO:0032988) | 2.65058176 |
| 93 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.64997618 |
| 94 | purine-containing compound salvage (GO:0043101) | 2.64684318 |
| 95 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.61829905 |
| 96 | mitochondrial transport (GO:0006839) | 2.60600982 |
| 97 | peptidyl-histidine modification (GO:0018202) | 2.60512373 |
| 98 | regulation of cellular amine metabolic process (GO:0033238) | 2.59766916 |
| 99 | signal peptide processing (GO:0006465) | 2.59676412 |
| 100 | histone mRNA metabolic process (GO:0008334) | 2.58214419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.04630484 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.70882085 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.20333539 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.04658548 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.75262526 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.63802699 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.57657944 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.29735608 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.23718730 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.22999978 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.12570718 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.92609425 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.85447474 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.67628033 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.44011982 |
| 16 | * MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.41228644 |
| 17 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.33672364 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.31541691 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.29769701 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.16618846 |
| 21 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.99237727 |
| 22 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.98876000 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.87241512 |
| 24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.85147030 |
| 25 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.82512549 |
| 26 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.74422875 |
| 27 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.72708179 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.70072408 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.67621742 |
| 30 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.66388299 |
| 31 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.61534932 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.57196515 |
| 33 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.54880794 |
| 34 | VDR_22108803_ChIP-Seq_LS180_Human | 1.54602135 |
| 35 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.53600319 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.53129878 |
| 37 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.51024697 |
| 38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47074944 |
| 39 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.47000538 |
| 40 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.44729270 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.40582674 |
| 42 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.40339652 |
| 43 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.40239305 |
| 44 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.40111813 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39738475 |
| 46 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38444629 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.38336952 |
| 48 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.34275763 |
| 49 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.32658385 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.31669364 |
| 51 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.30677105 |
| 52 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.28743640 |
| 53 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28261396 |
| 54 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22021938 |
| 55 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.21341941 |
| 56 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.21124436 |
| 57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.18298704 |
| 58 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.17185314 |
| 59 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.16326405 |
| 60 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.10157531 |
| 61 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.08656390 |
| 62 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08391933 |
| 63 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.07482792 |
| 64 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.06794408 |
| 65 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.06533782 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.06346525 |
| 67 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.06346525 |
| 68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.04652235 |
| 69 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.03434501 |
| 70 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.03059100 |
| 71 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.00369774 |
| 72 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.00136399 |
| 73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.99044691 |
| 74 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98359493 |
| 75 | P300_19829295_ChIP-Seq_ESCs_Human | 0.97745322 |
| 76 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.96063703 |
| 77 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.95872461 |
| 78 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.95154161 |
| 79 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94465750 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93684147 |
| 81 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.93144043 |
| 82 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93109016 |
| 83 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.92610670 |
| 84 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92601795 |
| 85 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.92314988 |
| 86 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91575112 |
| 87 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.91040936 |
| 88 | * ERG_20517297_ChIP-Seq_VCAP_Human | 0.90350812 |
| 89 | NCOR_22424771_ChIP-Seq_293T_Human | 0.90073662 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.89562124 |
| 91 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.89562124 |
| 92 | GATA3_26560356_Chip-Seq_TH2_Human | 0.88240668 |
| 93 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87631255 |
| 94 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.86558709 |
| 95 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.85534114 |
| 96 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.84843104 |
| 97 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.83986828 |
| 98 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.83963626 |
| 99 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.81789668 |
| 100 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.80637511 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 3.93261158 |
| 2 | MP0003880_abnormal_central_pattern | 2.86609548 |
| 3 | MP0004147_increased_porphyrin_level | 2.62285202 |
| 4 | MP0006036_abnormal_mitochondrial_physio | 2.34918038 |
| 5 | MP0005075_abnormal_melanosome_morpholog | 2.21252101 |
| 6 | MP0001529_abnormal_vocalization | 2.20764027 |
| 7 | MP0000372_irregular_coat_pigmentation | 2.18376723 |
| 8 | MP0003787_abnormal_imprinting | 2.13077957 |
| 9 | MP0008058_abnormal_DNA_repair | 2.10903887 |
| 10 | MP0009379_abnormal_foot_pigmentation | 2.07054935 |
| 11 | MP0003186_abnormal_redox_activity | 1.95324026 |
| 12 | MP0009046_muscle_twitch | 1.79864961 |
| 13 | MP0005671_abnormal_response_to | 1.79159964 |
| 14 | MP0005410_abnormal_fertilization | 1.67501326 |
| 15 | MP0008995_early_reproductive_senescence | 1.65616613 |
| 16 | MP0008877_abnormal_DNA_methylation | 1.64625694 |
| 17 | MP0003718_maternal_effect | 1.60214721 |
| 18 | MP0001968_abnormal_touch/_nociception | 1.60037239 |
| 19 | MP0002837_dystrophic_cardiac_calcinosis | 1.59587304 |
| 20 | MP0005646_abnormal_pituitary_gland | 1.59141351 |
| 21 | MP0002653_abnormal_ependyma_morphology | 1.56963626 |
| 22 | MP0005084_abnormal_gallbladder_morpholo | 1.56807477 |
| 23 | MP0001905_abnormal_dopamine_level | 1.56018480 |
| 24 | MP0008872_abnormal_physiological_respon | 1.55755126 |
| 25 | MP0002736_abnormal_nociception_after | 1.51668558 |
| 26 | MP0004142_abnormal_muscle_tone | 1.51224538 |
| 27 | MP0009697_abnormal_copulation | 1.50346077 |
| 28 | MP0002638_abnormal_pupillary_reflex | 1.49588430 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.46484228 |
| 30 | MP0002102_abnormal_ear_morphology | 1.46347094 |
| 31 | MP0001764_abnormal_homeostasis | 1.44995147 |
| 32 | MP0002095_abnormal_skin_pigmentation | 1.43951375 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.43385933 |
| 34 | MP0006072_abnormal_retinal_apoptosis | 1.41385389 |
| 35 | MP0001835_abnormal_antigen_presentation | 1.41205503 |
| 36 | MP0001853_heart_inflammation | 1.36407047 |
| 37 | MP0001984_abnormal_olfaction | 1.33119666 |
| 38 | MP0009745_abnormal_behavioral_response | 1.32807558 |
| 39 | MP0002272_abnormal_nervous_system | 1.30375440 |
| 40 | MP0001485_abnormal_pinna_reflex | 1.30334165 |
| 41 | MP0005367_renal/urinary_system_phenotyp | 1.29926704 |
| 42 | MP0000516_abnormal_urinary_system | 1.29926704 |
| 43 | MP0003786_premature_aging | 1.29693082 |
| 44 | MP0002138_abnormal_hepatobiliary_system | 1.27119492 |
| 45 | MP0008789_abnormal_olfactory_epithelium | 1.26919161 |
| 46 | MP0006292_abnormal_olfactory_placode | 1.22525149 |
| 47 | MP0005253_abnormal_eye_physiology | 1.21417531 |
| 48 | MP0005379_endocrine/exocrine_gland_phen | 1.20098995 |
| 49 | MP0005551_abnormal_eye_electrophysiolog | 1.19237964 |
| 50 | MP0009785_altered_susceptibility_to | 1.13788703 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.13087741 |
| 52 | MP0002148_abnormal_hypersensitivity_rea | 1.12596845 |
| 53 | MP0003136_yellow_coat_color | 1.10787646 |
| 54 | MP0005499_abnormal_olfactory_system | 1.04079961 |
| 55 | MP0005394_taste/olfaction_phenotype | 1.04079961 |
| 56 | MP0001486_abnormal_startle_reflex | 1.03855359 |
| 57 | MP0005636_abnormal_mineral_homeostasis | 1.03390066 |
| 58 | MP0003195_calcinosis | 1.03352528 |
| 59 | MP0003121_genomic_imprinting | 1.02859942 |
| 60 | MP0005174_abnormal_tail_pigmentation | 1.02408168 |
| 61 | MP0002163_abnormal_gland_morphology | 1.01052848 |
| 62 | MP0002928_abnormal_bile_duct | 1.00972109 |
| 63 | MP0002064_seizures | 0.99588330 |
| 64 | MP0005423_abnormal_somatic_nervous | 0.99061080 |
| 65 | MP0002822_catalepsy | 0.96358916 |
| 66 | MP0009764_decreased_sensitivity_to | 0.94571051 |
| 67 | MP0001501_abnormal_sleep_pattern | 0.93106877 |
| 68 | MP0005266_abnormal_metabolism | 0.91740957 |
| 69 | MP0005535_abnormal_body_temperature | 0.90787840 |
| 70 | MP0001929_abnormal_gametogenesis | 0.88870622 |
| 71 | MP0001800_abnormal_humoral_immune | 0.87532583 |
| 72 | MP0002572_abnormal_emotion/affect_behav | 0.86497966 |
| 73 | MP0002067_abnormal_sensory_capabilities | 0.86452050 |
| 74 | MP0002090_abnormal_vision | 0.84503282 |
| 75 | MP0000015_abnormal_ear_pigmentation | 0.84367047 |
| 76 | MP0002277_abnormal_respiratory_mucosa | 0.82251852 |
| 77 | MP0001970_abnormal_pain_threshold | 0.81274933 |
| 78 | MP0005332_abnormal_amino_acid | 0.80777204 |
| 79 | MP0005408_hypopigmentation | 0.80403329 |
| 80 | MP0003656_abnormal_erythrocyte_physiolo | 0.80335695 |
| 81 | MP0001727_abnormal_embryo_implantation | 0.79958581 |
| 82 | MP0002452_abnormal_antigen_presenting | 0.79411290 |
| 83 | MP0003698_abnormal_male_reproductive | 0.79243497 |
| 84 | MP0002938_white_spotting | 0.78743606 |
| 85 | MP0002723_abnormal_immune_serum | 0.77515693 |
| 86 | MP0002229_neurodegeneration | 0.77452923 |
| 87 | MP0004742_abnormal_vestibular_system | 0.75993196 |
| 88 | MP0002210_abnormal_sex_determination | 0.75952704 |
| 89 | MP0005000_abnormal_immune_tolerance | 0.75141589 |
| 90 | MP0002734_abnormal_mechanical_nocicepti | 0.75067555 |
| 91 | MP0001919_abnormal_reproductive_system | 0.74482576 |
| 92 | MP0004859_abnormal_synaptic_plasticity | 0.72622198 |
| 93 | MP0004885_abnormal_endolymph | 0.72601325 |
| 94 | MP0003011_delayed_dark_adaptation | 0.72154109 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 0.71985087 |
| 96 | MP0010386_abnormal_urinary_bladder | 0.71404098 |
| 97 | MP0009333_abnormal_splenocyte_physiolog | 0.71354282 |
| 98 | MP0002735_abnormal_chemical_nociception | 0.70766543 |
| 99 | MP0002557_abnormal_social/conspecific_i | 0.69421973 |
| 100 | MP0001819_abnormal_immune_cell | 0.69383825 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.21344985 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.97569566 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.73284142 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.62124804 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.56496094 |
| 6 | Acute encephalopathy (HP:0006846) | 4.45211190 |
| 7 | Increased CSF lactate (HP:0002490) | 4.42093526 |
| 8 | Hepatic necrosis (HP:0002605) | 4.14087638 |
| 9 | 3-Methylglutaconic aciduria (HP:0003535) | 4.05306796 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.91840639 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.68373167 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 3.52418275 |
| 13 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.40325679 |
| 14 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.40325679 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.21245216 |
| 16 | Cerebral edema (HP:0002181) | 3.14424917 |
| 17 | Lactic acidosis (HP:0003128) | 2.93590512 |
| 18 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.92979284 |
| 19 | Increased serum lactate (HP:0002151) | 2.91756316 |
| 20 | Exertional dyspnea (HP:0002875) | 2.91307010 |
| 21 | Respiratory failure (HP:0002878) | 2.82300323 |
| 22 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.75882492 |
| 23 | Increased muscle lipid content (HP:0009058) | 2.73729264 |
| 24 | Pancreatic cysts (HP:0001737) | 2.62804432 |
| 25 | Optic disc pallor (HP:0000543) | 2.58308351 |
| 26 | Abnormal number of erythroid precursors (HP:0012131) | 2.57689151 |
| 27 | Medial flaring of the eyebrow (HP:0010747) | 2.49173790 |
| 28 | Type I transferrin isoform profile (HP:0003642) | 2.47723591 |
| 29 | Exercise intolerance (HP:0003546) | 2.43615772 |
| 30 | Leukodystrophy (HP:0002415) | 2.42397877 |
| 31 | Myokymia (HP:0002411) | 2.41008554 |
| 32 | Emotional lability (HP:0000712) | 2.40868651 |
| 33 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.39046323 |
| 34 | Abnormality of midbrain morphology (HP:0002418) | 2.35500603 |
| 35 | Molar tooth sign on MRI (HP:0002419) | 2.35500603 |
| 36 | CNS demyelination (HP:0007305) | 2.35267815 |
| 37 | Pancreatic fibrosis (HP:0100732) | 2.28298183 |
| 38 | Congenital, generalized hypertrichosis (HP:0004540) | 2.28218246 |
| 39 | Methylmalonic acidemia (HP:0002912) | 2.27512550 |
| 40 | Lethargy (HP:0001254) | 2.26631068 |
| 41 | Gait imbalance (HP:0002141) | 2.24216372 |
| 42 | Methylmalonic aciduria (HP:0012120) | 2.23278479 |
| 43 | True hermaphroditism (HP:0010459) | 2.20003856 |
| 44 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.19805630 |
| 45 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.19805630 |
| 46 | Abnormal protein glycosylation (HP:0012346) | 2.19805630 |
| 47 | Abnormal glycosylation (HP:0012345) | 2.19805630 |
| 48 | Degeneration of anterior horn cells (HP:0002398) | 2.18905194 |
| 49 | Abnormality of the anterior horn cell (HP:0006802) | 2.18905194 |
| 50 | Microvesicular hepatic steatosis (HP:0001414) | 2.16498491 |
| 51 | Abnormality of renal resorption (HP:0011038) | 2.16315614 |
| 52 | Congenital primary aphakia (HP:0007707) | 2.14958830 |
| 53 | Focal motor seizures (HP:0011153) | 2.11926204 |
| 54 | Respiratory difficulties (HP:0002880) | 2.09932303 |
| 55 | Progressive microcephaly (HP:0000253) | 2.09645680 |
| 56 | Macrocytic anemia (HP:0001972) | 2.01076095 |
| 57 | Nephrogenic diabetes insipidus (HP:0009806) | 2.01009265 |
| 58 | Glycosuria (HP:0003076) | 1.93035025 |
| 59 | Abnormality of urine glucose concentration (HP:0011016) | 1.93035025 |
| 60 | Nephronophthisis (HP:0000090) | 1.92648641 |
| 61 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.91420734 |
| 62 | Panhypogammaglobulinemia (HP:0003139) | 1.89151352 |
| 63 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.88134319 |
| 64 | Dicarboxylic aciduria (HP:0003215) | 1.88134319 |
| 65 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.81471839 |
| 66 | X-linked dominant inheritance (HP:0001423) | 1.79999005 |
| 67 | Hypothermia (HP:0002045) | 1.77903829 |
| 68 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.77804261 |
| 69 | Generalized aminoaciduria (HP:0002909) | 1.77325189 |
| 70 | Aplastic anemia (HP:0001915) | 1.74308243 |
| 71 | Delusions (HP:0000746) | 1.72889083 |
| 72 | Increased serum pyruvate (HP:0003542) | 1.68626581 |
| 73 | Severe combined immunodeficiency (HP:0004430) | 1.68224460 |
| 74 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.67757654 |
| 75 | Gliosis (HP:0002171) | 1.66593024 |
| 76 | Neutropenia (HP:0001875) | 1.66384241 |
| 77 | Agammaglobulinemia (HP:0004432) | 1.65973123 |
| 78 | Cerebral hypomyelination (HP:0006808) | 1.65534130 |
| 79 | Severe visual impairment (HP:0001141) | 1.65199534 |
| 80 | Hyperglycinemia (HP:0002154) | 1.64861198 |
| 81 | Abnormality of the labia minora (HP:0012880) | 1.62918781 |
| 82 | Hyperphosphaturia (HP:0003109) | 1.62676657 |
| 83 | Reticulocytopenia (HP:0001896) | 1.61158623 |
| 84 | Amyotrophic lateral sclerosis (HP:0007354) | 1.60817231 |
| 85 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.60672010 |
| 86 | Abnormality of alanine metabolism (HP:0010916) | 1.60672010 |
| 87 | Hyperalaninemia (HP:0003348) | 1.60672010 |
| 88 | Abolished electroretinogram (ERG) (HP:0000550) | 1.60646700 |
| 89 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.60603980 |
| 90 | Congenital stationary night blindness (HP:0007642) | 1.59992024 |
| 91 | Abnormality of the renal medulla (HP:0100957) | 1.58596147 |
| 92 | Abnormal biliary tract physiology (HP:0012439) | 1.58040533 |
| 93 | Bile duct proliferation (HP:0001408) | 1.58040533 |
| 94 | Abnormality of the prostate (HP:0008775) | 1.57466138 |
| 95 | Abnormality of vitamin B metabolism (HP:0004340) | 1.56526217 |
| 96 | Constricted visual fields (HP:0001133) | 1.54822313 |
| 97 | Abnormality of B cell number (HP:0010975) | 1.54125193 |
| 98 | Delayed CNS myelination (HP:0002188) | 1.51869390 |
| 99 | B lymphocytopenia (HP:0010976) | 1.49659039 |
| 100 | Blindness (HP:0000618) | 1.49530682 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.30605198 |
| 2 | TRIM28 | 3.10479499 |
| 3 | MST4 | 3.08376499 |
| 4 | MAP4K2 | 2.52576043 |
| 5 | NME2 | 2.36957055 |
| 6 | SIK3 | 2.26846133 |
| 7 | BCR | 2.26789859 |
| 8 | MAP3K12 | 2.22685250 |
| 9 | BMPR1B | 2.20843742 |
| 10 | BCKDK | 2.04364090 |
| 11 | BUB1 | 1.99021337 |
| 12 | TESK1 | 1.97273371 |
| 13 | SRPK1 | 1.90303119 |
| 14 | TXK | 1.84037206 |
| 15 | EIF2AK3 | 1.72011384 |
| 16 | STK16 | 1.68868828 |
| 17 | CDK8 | 1.65936512 |
| 18 | EIF2AK1 | 1.65900314 |
| 19 | ERBB3 | 1.65409018 |
| 20 | VRK1 | 1.56107775 |
| 21 | CSNK1G3 | 1.51060080 |
| 22 | LIMK1 | 1.47243406 |
| 23 | MAPK13 | 1.43379594 |
| 24 | CDK19 | 1.40969870 |
| 25 | BMPR2 | 1.39946482 |
| 26 | NUAK1 | 1.39411365 |
| 27 | PLK4 | 1.36836725 |
| 28 | CSNK1G2 | 1.35761242 |
| 29 | FRK | 1.35417537 |
| 30 | WNK3 | 1.26442946 |
| 31 | CCNB1 | 1.24358457 |
| 32 | PIM2 | 1.24344611 |
| 33 | DYRK2 | 1.18764737 |
| 34 | TAOK3 | 1.17809904 |
| 35 | TESK2 | 1.14612549 |
| 36 | CSNK1A1L | 1.13887624 |
| 37 | DAPK1 | 1.13731751 |
| 38 | MAP3K4 | 1.09767549 |
| 39 | CSNK1G1 | 1.07394246 |
| 40 | MINK1 | 1.06880746 |
| 41 | MAP2K7 | 1.05101344 |
| 42 | OXSR1 | 1.03892376 |
| 43 | TNIK | 1.00379067 |
| 44 | PLK2 | 0.99072146 |
| 45 | DAPK2 | 0.98875697 |
| 46 | IKBKB | 0.96925403 |
| 47 | ZAK | 0.91003028 |
| 48 | NEK1 | 0.83469146 |
| 49 | ADRBK2 | 0.81602834 |
| 50 | GRK1 | 0.79488523 |
| 51 | CAMKK2 | 0.78399952 |
| 52 | PINK1 | 0.76158019 |
| 53 | PASK | 0.75724685 |
| 54 | STK39 | 0.73192884 |
| 55 | NME1 | 0.73119870 |
| 56 | MAP4K1 | 0.73030206 |
| 57 | PLK3 | 0.70956931 |
| 58 | TEC | 0.68224385 |
| 59 | ABL2 | 0.67329539 |
| 60 | PBK | 0.63472773 |
| 61 | PHKG2 | 0.61633359 |
| 62 | PHKG1 | 0.61633359 |
| 63 | ILK | 0.61157517 |
| 64 | GRK7 | 0.61050701 |
| 65 | BRSK2 | 0.60260549 |
| 66 | RPS6KA4 | 0.60030111 |
| 67 | PRKCG | 0.58710044 |
| 68 | PIK3CA | 0.58418994 |
| 69 | TAOK2 | 0.57714371 |
| 70 | PKN1 | 0.57442415 |
| 71 | LYN | 0.56786778 |
| 72 | RIPK4 | 0.55239621 |
| 73 | TGFBR1 | 0.54424269 |
| 74 | CSNK1A1 | 0.53268128 |
| 75 | CSNK2A2 | 0.52488260 |
| 76 | IKBKE | 0.51726613 |
| 77 | SCYL2 | 0.51479311 |
| 78 | WEE1 | 0.51040178 |
| 79 | INSRR | 0.51025467 |
| 80 | CSNK2A1 | 0.49529764 |
| 81 | MATK | 0.49439589 |
| 82 | SYK | 0.48769521 |
| 83 | KDR | 0.47468793 |
| 84 | MKNK1 | 0.46028873 |
| 85 | RPS6KA5 | 0.45769937 |
| 86 | EIF2AK2 | 0.45739031 |
| 87 | MARK3 | 0.44521215 |
| 88 | KIT | 0.44389536 |
| 89 | EPHA4 | 0.43426289 |
| 90 | PRKCE | 0.42188776 |
| 91 | BRSK1 | 0.41487117 |
| 92 | PAK3 | 0.40781818 |
| 93 | DAPK3 | 0.40171466 |
| 94 | PRKCQ | 0.39716264 |
| 95 | DYRK3 | 0.39214718 |
| 96 | MARK1 | 0.39054376 |
| 97 | PDK2 | 0.38139969 |
| 98 | TBK1 | 0.38104172 |
| 99 | PLK1 | 0.37030503 |
| 100 | MKNK2 | 0.35658108 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.87029639 |
| 2 | Parkinsons disease_Homo sapiens_hsa05012 | 4.08550465 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.08352526 |
| 4 | Protein export_Homo sapiens_hsa03060 | 4.05875504 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 3.42668956 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.68902780 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.63795775 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.48773117 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.39896115 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.24508955 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.15977042 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.07479530 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.86152227 |
| 14 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.80697875 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.80170281 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.74126079 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.73050434 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.68645491 |
| 19 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.59447920 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.55183986 |
| 21 | Mismatch repair_Homo sapiens_hsa03430 | 1.54171400 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.41316022 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.41134077 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.38052824 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.36777415 |
| 26 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.36475891 |
| 27 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.25103860 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.24445645 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.19142972 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.18026714 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16979615 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15281746 |
| 33 | DNA replication_Homo sapiens_hsa03030 | 1.13789983 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.10336868 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 1.07752741 |
| 36 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.06511776 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05715090 |
| 38 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.03355054 |
| 39 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.03268786 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 0.96810072 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.95485416 |
| 42 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.93596959 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.92248974 |
| 44 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.89857263 |
| 45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.86634364 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.85586421 |
| 47 | RNA transport_Homo sapiens_hsa03013 | 0.84268815 |
| 48 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.83335171 |
| 49 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.82533977 |
| 50 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.76867432 |
| 51 | Nicotine addiction_Homo sapiens_hsa05033 | 0.76267687 |
| 52 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.71538519 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.70540470 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70140867 |
| 55 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.70096746 |
| 56 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.69189421 |
| 57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.66347177 |
| 58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65328881 |
| 59 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.61047926 |
| 60 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.56847908 |
| 61 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.55841271 |
| 62 | Sulfur relay system_Homo sapiens_hsa04122 | 0.54419894 |
| 63 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54087730 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.47924828 |
| 65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.45048151 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44692281 |
| 67 | GABAergic synapse_Homo sapiens_hsa04727 | 0.44304756 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.44263916 |
| 69 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42582784 |
| 70 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.42387214 |
| 71 | Legionellosis_Homo sapiens_hsa05134 | 0.41543211 |
| 72 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.37904892 |
| 73 | Viral myocarditis_Homo sapiens_hsa05416 | 0.37452978 |
| 74 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.37312010 |
| 75 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.36976473 |
| 76 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.36704209 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.35033707 |
| 78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.34979895 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.33263258 |
| 80 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33258075 |
| 81 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32679536 |
| 82 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.32208472 |
| 83 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.29715394 |
| 84 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.27390356 |
| 85 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27204262 |
| 86 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.24878345 |
| 87 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.24482550 |
| 88 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.24321862 |
| 89 | Morphine addiction_Homo sapiens_hsa05032 | 0.23835376 |
| 90 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.22535566 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.21956452 |
| 92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.21289440 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.20461273 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.19689362 |
| 95 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.19673421 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.19551955 |
| 97 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.19219891 |
| 98 | Phagosome_Homo sapiens_hsa04145 | 0.18915304 |
| 99 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.16723719 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.16254293 |

