ZNF736

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein K11-linked deubiquitination (GO:0035871)6.96390105
2regulation of B cell receptor signaling pathway (GO:0050855)4.91274004
3monoubiquitinated protein deubiquitination (GO:0035520)4.80416799
4protein K48-linked deubiquitination (GO:0071108)4.65130713
5cilium or flagellum-dependent cell motility (GO:0001539)4.56663792
6interkinetic nuclear migration (GO:0022027)4.26747396
7positive regulation of granulocyte differentiation (GO:0030854)4.26736049
8lipid translocation (GO:0034204)4.07399067
9phospholipid translocation (GO:0045332)4.07399067
10cellular response to ethanol (GO:0071361)4.03250176
11protein K63-linked deubiquitination (GO:0070536)4.01438199
12B cell receptor signaling pathway (GO:0050853)3.99318305
13positive regulation of gamma-delta T cell activation (GO:0046645)3.93592483
14phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.88814314
15histone H3-K9 methylation (GO:0051567)3.86488323
16regulation of establishment of cell polarity (GO:2000114)3.80489620
17activated T cell proliferation (GO:0050798)3.79904902
18histone H3-K9 modification (GO:0061647)3.79762455
19establishment of protein localization to Golgi (GO:0072600)3.70732005
20positive regulation of developmental pigmentation (GO:0048087)3.64977490
21neural tube formation (GO:0001841)3.60108479
22negative regulation of interleukin-8 production (GO:0032717)3.39482281
23nuclear pore organization (GO:0006999)3.35331574
24regulation of pigment cell differentiation (GO:0050932)3.23165091
25synapsis (GO:0007129)3.22736521
26histone H3-K4 trimethylation (GO:0080182)3.22469929
27interferon-gamma production (GO:0032609)3.18692416
28histone H3-K36 demethylation (GO:0070544)3.16834860
29centriole replication (GO:0007099)3.16349989
30positive regulation of B cell differentiation (GO:0045579)3.15922431
31regulation of gamma-delta T cell differentiation (GO:0045586)3.13056773
32DNA double-strand break processing (GO:0000729)3.12571527
33histone mRNA catabolic process (GO:0071044)3.11692009
34hematopoietic stem cell proliferation (GO:0071425)3.08902764
35histone lysine methylation (GO:0034968)3.08788418
36negative regulation of calcium ion transport into cytosol (GO:0010523)3.07761095
37definitive hemopoiesis (GO:0060216)3.07022300
38negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.06733253
39resolution of meiotic recombination intermediates (GO:0000712)3.05857555
40regulation of gamma-delta T cell activation (GO:0046643)3.05401570
41piRNA metabolic process (GO:0034587)3.03704065
42retinal cone cell development (GO:0046549)2.99851650
43negative regulation of circadian rhythm (GO:0042754)2.99462055
44meiotic chromosome segregation (GO:0045132)2.98893480
45regulation of establishment or maintenance of cell polarity (GO:0032878)2.98568745
46peptidyl-lysine trimethylation (GO:0018023)2.97889341
47replication fork processing (GO:0031297)2.95697822
48cytoplasmic mRNA processing body assembly (GO:0033962)2.92834408
49negative thymic T cell selection (GO:0045060)2.91917191
50negative T cell selection (GO:0043383)2.88985349
51positive T cell selection (GO:0043368)2.88149580
52regulation of histone H3-K9 methylation (GO:0051570)2.87698580
53epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.86561539
54V(D)J recombination (GO:0033151)2.82808257
55Golgi to endosome transport (GO:0006895)2.82345972
56glycoprotein catabolic process (GO:0006516)2.81561692
57retrograde transport, vesicle recycling within Golgi (GO:0000301)2.77053206
58centrosome duplication (GO:0051298)2.75244082
59hepatocyte apoptotic process (GO:0097284)2.74473907
60protein targeting to Golgi (GO:0000042)2.73988946
61reflex (GO:0060004)2.69462428
62peptidyl-lysine methylation (GO:0018022)2.66317852
63dosage compensation (GO:0007549)2.65872058
64gene silencing by RNA (GO:0031047)2.64954816
65indolalkylamine catabolic process (GO:0046218)2.64627409
66tryptophan catabolic process (GO:0006569)2.64627409
67indole-containing compound catabolic process (GO:0042436)2.64627409
68N-terminal protein amino acid acetylation (GO:0006474)2.64601013
69granulocyte differentiation (GO:0030851)2.63731172
70nuclear pore complex assembly (GO:0051292)2.63198224
71serotonin receptor signaling pathway (GO:0007210)2.61003564
72regulation of female gonad development (GO:2000194)2.61003095
73positive regulation of DNA-templated transcription, initiation (GO:2000144)2.60402515
74regulation of granulocyte differentiation (GO:0030852)2.56570225
75regulation of meiosis I (GO:0060631)2.55700264
76snRNA transcription (GO:0009301)2.49341944
77interleukin-6-mediated signaling pathway (GO:0070102)2.48242208
78regulation of B cell differentiation (GO:0045577)2.47575423
79DNA methylation involved in gamete generation (GO:0043046)2.46715794
80rRNA catabolic process (GO:0016075)2.46613113
81positive thymic T cell selection (GO:0045059)2.42504249
82meiotic cell cycle (GO:0051321)2.42347133
83photoreceptor cell maintenance (GO:0045494)2.42148945
84histone H3-K4 methylation (GO:0051568)2.41636093
85cellular extravasation (GO:0045123)2.41479267
86nerve growth factor signaling pathway (GO:0038180)2.40978096
87indolalkylamine metabolic process (GO:0006586)2.40381649
88peptidyl-lysine dimethylation (GO:0018027)2.40271638
89mitotic sister chromatid cohesion (GO:0007064)2.40176366
90negative regulation of mast cell activation (GO:0033004)2.39217335
91tryptophan metabolic process (GO:0006568)2.37780663
92histone methylation (GO:0016571)2.37483486
93righting reflex (GO:0060013)2.36249590
94regulation of DNA endoreduplication (GO:0032875)2.35861911
95positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.33969742
96thyroid hormone metabolic process (GO:0042403)2.33592687
97regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.33488351
98regulation of MHC class II biosynthetic process (GO:0045346)2.33161371
99T cell selection (GO:0045058)2.32733821
100positive regulation of vasculogenesis (GO:2001214)2.32592514

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.36295141
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.31053814
3GBX2_23144817_ChIP-Seq_PC3_Human3.09424007
4IGF1R_20145208_ChIP-Seq_DFB_Human2.86596317
5IRF8_22096565_ChIP-ChIP_GC-B_Human2.80656266
6CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.68624915
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.63714159
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.53292183
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.39698198
10TAF15_26573619_Chip-Seq_HEK293_Human2.33156103
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.32675270
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.21454941
13AR_21572438_ChIP-Seq_LNCaP_Human2.20103744
14SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.16597271
15ER_23166858_ChIP-Seq_MCF-7_Human2.13993012
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.12914640
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.10117021
18SCL_19346495_ChIP-Seq_HPC-7_Human1.87995312
19ZFP57_27257070_Chip-Seq_ESCs_Mouse1.85568999
20GATA1_22025678_ChIP-Seq_K562_Human1.85164426
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.83561108
22EWS_26573619_Chip-Seq_HEK293_Human1.79861543
23FUS_26573619_Chip-Seq_HEK293_Human1.78285523
24STAT3_23295773_ChIP-Seq_U87_Human1.78161075
25* ZNF274_21170338_ChIP-Seq_K562_Hela1.77728604
26FLI1_27457419_Chip-Seq_LIVER_Mouse1.77417467
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.75635595
28VDR_22108803_ChIP-Seq_LS180_Human1.66853955
29RUNX_20019798_ChIP-Seq_JUKART_Human1.65398821
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62165218
31TCF4_23295773_ChIP-Seq_U87_Human1.59470049
32IRF8_21731497_ChIP-ChIP_J774_Mouse1.59421796
33SMAD4_21799915_ChIP-Seq_A2780_Human1.55841513
34IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.51416410
35VDR_24787735_ChIP-Seq_THP-1_Human1.49984731
36ESR1_20079471_ChIP-ChIP_T-47D_Human1.48679752
37VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.48316460
38P300_19829295_ChIP-Seq_ESCs_Human1.44813722
39IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44698842
40CBP_20019798_ChIP-Seq_JUKART_Human1.44698842
41* MYB_26560356_Chip-Seq_TH2_Human1.42901295
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41736341
43AR_25329375_ChIP-Seq_VCAP_Human1.40974245
44STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40569993
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.37120611
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.36524124
47CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.34235719
48TP53_16413492_ChIP-PET_HCT116_Human1.33526541
49UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33203416
50PCGF2_27294783_Chip-Seq_ESCs_Mouse1.33063363
51GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.32226913
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32113212
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31639225
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.31387879
55EZH2_27294783_Chip-Seq_NPCs_Mouse1.29434406
56NR3C1_21868756_ChIP-Seq_MCF10A_Human1.27205557
57FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.27194405
58RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.26525360
59PRDM14_20953172_ChIP-Seq_ESCs_Human1.26140904
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24780599
61FLI1_21867929_ChIP-Seq_TH2_Mouse1.24488068
62TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.24133342
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23169085
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23169085
65ARNT_22903824_ChIP-Seq_MCF-7_Human1.23085107
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.21524354
67IRF8_27001747_Chip-Seq_BMDM_Mouse1.20258732
68FOXM1_26456572_ChIP-Seq_MCF-7_Human1.20198821
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19239926
70DROSHA_22980978_ChIP-Seq_HELA_Human1.19228359
71NANOG_18555785_Chip-Seq_ESCs_Mouse1.18861577
72BCAT_22108803_ChIP-Seq_LS180_Human1.18812877
73AHR_22903824_ChIP-Seq_MCF-7_Human1.15729967
74GATA3_27048872_Chip-Seq_THYMUS_Human1.15567365
75E2F4_17652178_ChIP-ChIP_JURKAT_Human1.14128714
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.13808660
77RUNX2_22187159_ChIP-Seq_PCA_Human1.12405111
78SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12091500
79NFE2_27457419_Chip-Seq_LIVER_Mouse1.11993322
80ZNF217_24962896_ChIP-Seq_MCF-7_Human1.10904809
81OCT4_21477851_ChIP-Seq_ESCs_Mouse1.09564855
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08320653
83TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08279734
84Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.07580561
85FOXA1_21572438_ChIP-Seq_LNCaP_Human1.06849384
86PKCTHETA_26484144_Chip-Seq_BREAST_Human1.06498663
87E2F1_18555785_Chip-Seq_ESCs_Mouse1.06023728
88EZH2_22144423_ChIP-Seq_EOC_Human1.05929729
89* MYB_26560356_Chip-Seq_TH1_Human1.05760750
90SMRT_27268052_Chip-Seq_Bcells_Human1.05275738
91MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.04140014
92TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.03800058
93CDX2_22108803_ChIP-Seq_LS180_Human1.03536849
94CRX_20693478_ChIP-Seq_RETINA_Mouse1.02662161
95GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01903195
96PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00520349
97OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.00304941
98SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.99795049
99BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98670164
100CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97940623

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication6.31350741
2MP0000569_abnormal_digit_pigmentation4.03456851
3MP0002009_preneoplasia3.67296723
4MP0003183_abnormal_peptide_metabolism3.58856263
5MP0005310_abnormal_salivary_gland3.00942897
6MP0002396_abnormal_hematopoietic_system2.83057397
7MP0002138_abnormal_hepatobiliary_system2.56411766
8MP0008877_abnormal_DNA_methylation2.40121603
9MP0001835_abnormal_antigen_presentation2.34682674
10MP0003763_abnormal_thymus_physiology2.32962870
11MP0010094_abnormal_chromosome_stability2.29204419
12MP0002166_altered_tumor_susceptibility2.19181133
13MP0001800_abnormal_humoral_immune2.06466149
14MP0002822_catalepsy1.96431660
15MP0002006_tumorigenesis1.94717784
16MP0004381_abnormal_hair_follicle1.85670525
17MP0009278_abnormal_bone_marrow1.83829552
18MP0000383_abnormal_hair_follicle1.72081461
19MP0005075_abnormal_melanosome_morpholog1.70412652
20MP0005174_abnormal_tail_pigmentation1.66709693
21MP0003787_abnormal_imprinting1.64728507
22MP0004808_abnormal_hematopoietic_stem1.57839989
23MP0002398_abnormal_bone_marrow1.53716479
24MP0002928_abnormal_bile_duct1.49083703
25MP0005397_hematopoietic_system_phenotyp1.48627496
26MP0001545_abnormal_hematopoietic_system1.48627496
27MP0001873_stomach_inflammation1.47751016
28MP0005387_immune_system_phenotype1.45602679
29MP0001790_abnormal_immune_system1.45602679
30MP0002452_abnormal_antigen_presenting1.44994340
31MP0000685_abnormal_immune_system1.44209887
32MP0008058_abnormal_DNA_repair1.44111774
33MP0000703_abnormal_thymus_morphology1.39903560
34MP0002420_abnormal_adaptive_immunity1.39290272
35MP0001819_abnormal_immune_cell1.35285651
36MP0002723_abnormal_immune_serum1.35134756
37MP0004043_abnormal_pH_regulation1.32648062
38MP0010678_abnormal_skin_adnexa1.32279554
39MP0005000_abnormal_immune_tolerance1.28897896
40MP0000015_abnormal_ear_pigmentation1.28812009
41MP0000716_abnormal_immune_system1.27506322
42MP0005647_abnormal_sex_gland1.26128266
43MP0003724_increased_susceptibility_to1.24453185
44MP0005451_abnormal_body_composition1.24351492
45MP0000689_abnormal_spleen_morphology1.22517852
46MP0000427_abnormal_hair_cycle1.20688682
47MP0003045_fibrosis1.20296676
48MP0002722_abnormal_immune_system1.16733656
49MP0001501_abnormal_sleep_pattern1.14831575
50MP0002735_abnormal_chemical_nociception1.13723523
51MP0005671_abnormal_response_to1.13124106
52MP0005551_abnormal_eye_electrophysiolog1.12509445
53MP0002405_respiratory_system_inflammati1.09856619
54MP0005670_abnormal_white_adipose1.07225867
55MP0008961_abnormal_basal_metabolism1.06310333
56MP0001929_abnormal_gametogenesis0.99722361
57MP0002419_abnormal_innate_immunity0.98859875
58MP0003943_abnormal_hepatobiliary_system0.97520501
59MP0002429_abnormal_blood_cell0.95252821
60MP0002095_abnormal_skin_pigmentation0.94957355
61MP0006082_CNS_inflammation0.93370279
62MP0001986_abnormal_taste_sensitivity0.92681557
63MP0001968_abnormal_touch/_nociception0.92106450
64MP0008995_early_reproductive_senescence0.90961565
65MP0000371_diluted_coat_color0.90726902
66MP0005025_abnormal_response_to0.88183087
67MP0009046_muscle_twitch0.87243975
68MP0005646_abnormal_pituitary_gland0.86831196
69MP0003646_muscle_fatigue0.86580223
70MP0010155_abnormal_intestine_physiology0.85470181
71MP0003698_abnormal_male_reproductive0.85450670
72MP0003300_gastrointestinal_ulcer0.84950202
73MP0001919_abnormal_reproductive_system0.84943951
74MP0005464_abnormal_platelet_physiology0.83901383
75MP0010307_abnormal_tumor_latency0.83115862
76MP0002148_abnormal_hypersensitivity_rea0.81095702
77MP0003303_peritoneal_inflammation0.78654143
78MP0001486_abnormal_startle_reflex0.78604837
79MP0009115_abnormal_fat_cell0.78513507
80MP0002210_abnormal_sex_determination0.75507370
81MP0001879_abnormal_lymphatic_vessel0.75259165
82MP0003656_abnormal_erythrocyte_physiolo0.75112369
83MP0001145_abnormal_male_reproductive0.73540472
84MP0005253_abnormal_eye_physiology0.73289888
85MP0002132_abnormal_respiratory_system0.72556832
86MP0002019_abnormal_tumor_incidence0.66215416
87MP0000653_abnormal_sex_gland0.65399588
88MP0003077_abnormal_cell_cycle0.65370473
89MP0005389_reproductive_system_phenotype0.64481031
90MP0000372_irregular_coat_pigmentation0.63843658
91MP0001851_eye_inflammation0.63373971
92MP0005266_abnormal_metabolism0.62094506
93MP0003252_abnormal_bile_duct0.61993095
94MP0002970_abnormal_white_adipose0.61764961
95MP0010386_abnormal_urinary_bladder0.61459788
96MP0001845_abnormal_inflammatory_respons0.60216618
97MP0004947_skin_inflammation0.59327384
98MP0008872_abnormal_physiological_respon0.59137780
99MP0002876_abnormal_thyroid_physiology0.58790290
100MP0003866_abnormal_defecation0.57627414

Predicted human phenotypes

RankGene SetZ-score
1Panhypogammaglobulinemia (HP:0003139)4.81281917
2Abnormality of B cell number (HP:0010975)3.82559978
3B lymphocytopenia (HP:0010976)3.81573283
4Hyperventilation (HP:0002883)3.64239437
5Absent/shortened dynein arms (HP:0200106)3.49835041
6Dynein arm defect of respiratory motile cilia (HP:0012255)3.49835041
7Chronic hepatic failure (HP:0100626)3.41595754
8Hypoplasia of the thymus (HP:0000778)3.22329843
9T lymphocytopenia (HP:0005403)3.21547684
10Recurrent viral infections (HP:0004429)3.11159946
11Thyroiditis (HP:0100646)3.08887371
12Recurrent fungal infections (HP:0002841)3.00227166
13Attenuation of retinal blood vessels (HP:0007843)2.92403559
14Abnormality of T cell number (HP:0011839)2.88728996
15Chronic mucocutaneous candidiasis (HP:0002728)2.85597383
16Recurrent cutaneous fungal infections (HP:0011370)2.85597383
17Acute myeloid leukemia (HP:0004808)2.78176647
18Severe combined immunodeficiency (HP:0004430)2.77401671
19Pancreatic cysts (HP:0001737)2.77296765
20Gaze-evoked nystagmus (HP:0000640)2.76870514
21Abnormality of the fingertips (HP:0001211)2.76486082
22Bony spicule pigmentary retinopathy (HP:0007737)2.72421981
23Genetic anticipation (HP:0003743)2.69227070
24Agammaglobulinemia (HP:0004432)2.67785952
25Abnormal delayed hypersensitivity skin test (HP:0002963)2.66723850
26Protruding tongue (HP:0010808)2.61051471
27Acute lymphatic leukemia (HP:0006721)2.59877625
28Eosinophilia (HP:0001880)2.58283434
29Constricted visual fields (HP:0001133)2.54291769
30Optic neuritis (HP:0100653)2.53858320
31Retrobulbar optic neuritis (HP:0100654)2.53858320
32Volvulus (HP:0002580)2.53323007
33Hypoproteinemia (HP:0003075)2.52978854
34Colitis (HP:0002583)2.43750944
35Decreased circulating renin level (HP:0003351)2.40955259
36Widely spaced teeth (HP:0000687)2.39278719
37Congenital sensorineural hearing impairment (HP:0008527)2.36570421
38Combined immunodeficiency (HP:0005387)2.36285583
39Meningitis (HP:0001287)2.32739116
40Abnormal ciliary motility (HP:0012262)2.31169486
41Granulocytopenia (HP:0001913)2.29290500
42Lower limb hyperreflexia (HP:0002395)2.28983260
43Keratoconjunctivitis (HP:0001096)2.26248534
44True hermaphroditism (HP:0010459)2.23405635
45Central scotoma (HP:0000603)2.21154147
46Encephalitis (HP:0002383)2.16867498
47Abnormality of T cells (HP:0002843)2.16286291
48Clumsiness (HP:0002312)2.16205508
49Absent rod-and cone-mediated responses on ERG (HP:0007688)2.14775732
50Recurrent sinusitis (HP:0011108)2.12982399
51Abolished electroretinogram (ERG) (HP:0000550)2.12477067
52Stomach cancer (HP:0012126)2.12406896
53Increased neuronal autofluorescent lipopigment (HP:0002074)2.10152235
54Fair hair (HP:0002286)2.07942974
55Progressive cerebellar ataxia (HP:0002073)2.06064925
56Chromsome breakage (HP:0040012)2.04213105
57Abnormality of eosinophils (HP:0001879)2.03827105
58Recurrent bronchitis (HP:0002837)2.02909756
59Chromosomal breakage induced by crosslinking agents (HP:0003221)2.00373986
60Orchitis (HP:0100796)2.00244900
61Myositis (HP:0100614)1.99668517
62Keratoconjunctivitis sicca (HP:0001097)1.99112761
63Prominent nose (HP:0000448)1.99010900
64Abnormality of chromosome stability (HP:0003220)1.98102645
65Pancreatic fibrosis (HP:0100732)1.97898909
66Viral hepatitis (HP:0006562)1.97550254
67Febrile seizures (HP:0002373)1.96309702
68Clubbing of toes (HP:0100760)1.95718729
69Absent speech (HP:0001344)1.93147260
70Tubulointerstitial nephritis (HP:0001970)1.92691408
71Generalized hypopigmentation of hair (HP:0011358)1.91498689
72Nephronophthisis (HP:0000090)1.90104552
73Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.89081001
74Abnormality of the renal medulla (HP:0100957)1.88101913
75Abnormality of the renal cortex (HP:0011035)1.87139663
76Abnormal respiratory motile cilium physiology (HP:0012261)1.86953926
77Bronchiectasis (HP:0002110)1.84995674
78Sandal gap (HP:0001852)1.84544351
79Recurrent skin infections (HP:0001581)1.80721486
80Autoimmune hemolytic anemia (HP:0001890)1.80558202
81Recurrent bacterial skin infections (HP:0005406)1.79967476
82Truncal obesity (HP:0001956)1.78365848
83Scotoma (HP:0000575)1.78236826
84IgG deficiency (HP:0004315)1.78090561
85Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.77660820
86Inflammation of the large intestine (HP:0002037)1.76395546
87Stomatitis (HP:0010280)1.75160355
88Abnormality of the prostate (HP:0008775)1.74834194
89Neoplasm of the tracheobronchial system (HP:0100552)1.73196211
90Bronchitis (HP:0012387)1.72070222
91Congenital stationary night blindness (HP:0007642)1.71953126
92Abnormality of T cell physiology (HP:0011840)1.71249163
93IgM deficiency (HP:0002850)1.70292725
94Molar tooth sign on MRI (HP:0002419)1.70093766
95Abnormality of midbrain morphology (HP:0002418)1.70093766
96Abnormal respiratory motile cilium morphology (HP:0005938)1.69715144
97Abnormal respiratory epithelium morphology (HP:0012253)1.69715144
98Increased cerebral lipofuscin (HP:0011813)1.68530051
99Abnormality of male internal genitalia (HP:0000022)1.66851013
100Hyperkalemia (HP:0002153)1.66082377

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK7.44206896
2BLK2.64261075
3TAOK32.32777511
4CDK122.15021062
5ACVR1B1.99445106
6EIF2AK31.95351719
7PIK3CG1.93492891
8ZAK1.75365266
9TXK1.73671748
10WNK31.65538868
11TEC1.59946118
12RIPK41.54081253
13MKNK21.51276334
14BRD41.50859532
15TRPM71.49716191
16BTK1.45830217
17EEF2K1.42356226
18BMPR1B1.41975604
19KIT1.40548317
20MAPK131.32898671
21MAP3K131.30097537
22IRAK11.28808074
23PNCK1.27784025
24SYK1.26137482
25FES1.25548124
26MAP4K11.24544787
27AKT31.22920647
28NLK1.22619403
29YES11.14724042
30SGK21.13717965
31NTRK31.12935066
32MAP3K101.12829008
33BMPR21.11561396
34MAP3K21.06932942
35ITK1.04674985
36RPS6KB21.01823921
37MARK31.01061570
38MAP3K141.00473081
39PINK10.98604109
40JAK10.97567094
41MAP3K70.95756159
42TNK20.95341140
43TYK20.83770309
44FGFR30.83582131
45NEK60.83111424
46LYN0.82564570
47CSF1R0.82224263
48HCK0.81030229
49NUAK10.78771625
50STK38L0.77505977
51BRSK20.77186160
52IKBKB0.74300033
53IKBKE0.71898507
54CDK60.71518715
55CDK30.71207070
56PRPF4B0.70405461
57MAP3K40.70390830
58ADRBK20.70092160
59CAMK1G0.69840834
60MELK0.69663862
61MAPK150.69101342
62INSRR0.68727792
63MAPK110.67701817
64JAK20.67416642
65TGFBR10.67085490
66STK30.66760300
67LCK0.66032740
68CDK40.65631419
69MKNK10.65013965
70PIK3CA0.64564871
71RPS6KB10.62275685
72WNK10.60603436
73TLK10.60477490
74NEK20.60119858
75ATR0.58745113
76WEE10.56481375
77CCNB10.56335344
78RET0.54529643
79SGK10.53469852
80MAPKAPK30.52502098
81ATM0.50418874
82PRKCQ0.50404073
83SGK30.49747471
84CHUK0.49314224
85SIK20.47511543
86VRK10.47236924
87PDK10.45085236
88CAMKK20.44300618
89PLK40.42974944
90FER0.41992204
91CAMK40.41886736
92IRAK20.41461514
93EIF2AK20.40884283
94IRAK40.40624907
95CHEK20.40046244
96PIM10.39978509
97ZAP700.38578712
98PTK2B0.38566815
99HIPK20.37945131
100MAPK70.37427583

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034502.51852711
2Dorso-ventral axis formation_Homo sapiens_hsa043202.27182166
3B cell receptor signaling pathway_Homo sapiens_hsa046622.25321992
4Primary immunodeficiency_Homo sapiens_hsa053402.13521339
5Asthma_Homo sapiens_hsa053101.99722368
6Intestinal immune network for IgA production_Homo sapiens_hsa046721.74828553
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.67599902
8Allograft rejection_Homo sapiens_hsa053301.65183939
9Graft-versus-host disease_Homo sapiens_hsa053321.61968003
10Autoimmune thyroid disease_Homo sapiens_hsa053201.56922512
11Fanconi anemia pathway_Homo sapiens_hsa034601.56493273
12Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.54134767
13ABC transporters_Homo sapiens_hsa020101.38708123
14Leishmaniasis_Homo sapiens_hsa051401.36980411
15T cell receptor signaling pathway_Homo sapiens_hsa046601.35833937
16Selenocompound metabolism_Homo sapiens_hsa004501.35409175
17Phosphatidylinositol signaling system_Homo sapiens_hsa040701.34058377
18Lysine degradation_Homo sapiens_hsa003101.29770855
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.28577825
20Type I diabetes mellitus_Homo sapiens_hsa049401.26700065
21Acute myeloid leukemia_Homo sapiens_hsa052211.24173799
22Homologous recombination_Homo sapiens_hsa034401.21080809
23Non-small cell lung cancer_Homo sapiens_hsa052231.20923316
24Staphylococcus aureus infection_Homo sapiens_hsa051501.20853205
25Platelet activation_Homo sapiens_hsa046111.17200799
26Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15390241
27NOD-like receptor signaling pathway_Homo sapiens_hsa046211.15164191
28Osteoclast differentiation_Homo sapiens_hsa043801.14591801
29Systemic lupus erythematosus_Homo sapiens_hsa053221.12915148
30Measles_Homo sapiens_hsa051621.07442789
31FoxO signaling pathway_Homo sapiens_hsa040681.05304865
32Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.02297541
33Prolactin signaling pathway_Homo sapiens_hsa049171.02082763
34Hematopoietic cell lineage_Homo sapiens_hsa046401.01902476
35Choline metabolism in cancer_Homo sapiens_hsa052311.01242137
36mTOR signaling pathway_Homo sapiens_hsa041501.00433464
37Salivary secretion_Homo sapiens_hsa049700.95671464
38Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95104438
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94788119
40Phototransduction_Homo sapiens_hsa047440.94747476
41Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.94443982
42Olfactory transduction_Homo sapiens_hsa047400.94057520
43Chronic myeloid leukemia_Homo sapiens_hsa052200.93041453
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91851980
45Inositol phosphate metabolism_Homo sapiens_hsa005620.89830009
46Pancreatic cancer_Homo sapiens_hsa052120.89543842
47Influenza A_Homo sapiens_hsa051640.88793380
48Linoleic acid metabolism_Homo sapiens_hsa005910.88321081
49Taste transduction_Homo sapiens_hsa047420.85346409
50Toxoplasmosis_Homo sapiens_hsa051450.84643024
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84304893
52Herpes simplex infection_Homo sapiens_hsa051680.84248402
53Antigen processing and presentation_Homo sapiens_hsa046120.84108340
54NF-kappa B signaling pathway_Homo sapiens_hsa040640.83732157
55Ether lipid metabolism_Homo sapiens_hsa005650.82910354
56RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82540248
57Tuberculosis_Homo sapiens_hsa051520.80959917
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.80620969
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80620724
60Calcium signaling pathway_Homo sapiens_hsa040200.77224140
61Glioma_Homo sapiens_hsa052140.76982036
62Cholinergic synapse_Homo sapiens_hsa047250.76862245
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76333803
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.75494976
65Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75426774
66Prostate cancer_Homo sapiens_hsa052150.73961518
67Hepatitis B_Homo sapiens_hsa051610.73389446
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.72475021
69Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72005089
70Oxytocin signaling pathway_Homo sapiens_hsa049210.68327621
71Glycerophospholipid metabolism_Homo sapiens_hsa005640.68039255
72Butanoate metabolism_Homo sapiens_hsa006500.66464521
73Viral carcinogenesis_Homo sapiens_hsa052030.66384146
74Colorectal cancer_Homo sapiens_hsa052100.66009452
75Long-term depression_Homo sapiens_hsa047300.65154259
76Type II diabetes mellitus_Homo sapiens_hsa049300.65111083
77Estrogen signaling pathway_Homo sapiens_hsa049150.64312503
78ErbB signaling pathway_Homo sapiens_hsa040120.64250317
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.63583946
80Toll-like receptor signaling pathway_Homo sapiens_hsa046200.63494781
81Serotonergic synapse_Homo sapiens_hsa047260.62631416
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61392169
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.61283461
84MicroRNAs in cancer_Homo sapiens_hsa052060.59471065
85cAMP signaling pathway_Homo sapiens_hsa040240.58376686
86Renal cell carcinoma_Homo sapiens_hsa052110.57910073
87TNF signaling pathway_Homo sapiens_hsa046680.56839913
88p53 signaling pathway_Homo sapiens_hsa041150.56389932
89Alcoholism_Homo sapiens_hsa050340.56240430
90Endometrial cancer_Homo sapiens_hsa052130.56135048
91Ovarian steroidogenesis_Homo sapiens_hsa049130.55847666
92cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54806069
93Basal transcription factors_Homo sapiens_hsa030220.54309539
94Morphine addiction_Homo sapiens_hsa050320.54221066
95Nicotine addiction_Homo sapiens_hsa050330.53369130
96Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53202404
97Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53080975
98Chemokine signaling pathway_Homo sapiens_hsa040620.52510592
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.50745938
100HTLV-I infection_Homo sapiens_hsa051660.49583438

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »