

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.34722523 |
| 2 | establishment of integrated proviral latency (GO:0075713) | 4.31282976 |
| 3 | DNA strand elongation (GO:0022616) | 4.21438713 |
| 4 | regulation of helicase activity (GO:0051095) | 4.02172151 |
| 5 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.00833467 |
| 6 | termination of RNA polymerase III transcription (GO:0006386) | 3.90240557 |
| 7 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.90240557 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.84897815 |
| 9 | proteasome assembly (GO:0043248) | 3.84342103 |
| 10 | CENP-A containing nucleosome assembly (GO:0034080) | 3.78689197 |
| 11 | chromatin remodeling at centromere (GO:0031055) | 3.71860942 |
| 12 | spliceosomal snRNP assembly (GO:0000387) | 3.63317541 |
| 13 | cullin deneddylation (GO:0010388) | 3.62613045 |
| 14 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.50574129 |
| 15 | pseudouridine synthesis (GO:0001522) | 3.49971400 |
| 16 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.48953868 |
| 17 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.48953868 |
| 18 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.46692513 |
| 19 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.46692513 |
| 20 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.44422694 |
| 21 | regulation of mitochondrial translation (GO:0070129) | 3.42624934 |
| 22 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.40497675 |
| 23 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.40076618 |
| 24 | establishment of viral latency (GO:0019043) | 3.39076964 |
| 25 | telomere maintenance via recombination (GO:0000722) | 3.36901859 |
| 26 | protein deneddylation (GO:0000338) | 3.36478571 |
| 27 | ribosomal large subunit biogenesis (GO:0042273) | 3.36125575 |
| 28 | DNA replication checkpoint (GO:0000076) | 3.34467179 |
| 29 | ribosome assembly (GO:0042255) | 3.33267644 |
| 30 | maturation of 5.8S rRNA (GO:0000460) | 3.31256334 |
| 31 | histone mRNA metabolic process (GO:0008334) | 3.30331769 |
| 32 | DNA damage response, detection of DNA damage (GO:0042769) | 3.29718704 |
| 33 | regulation of translational fidelity (GO:0006450) | 3.28433637 |
| 34 | nuclear pore organization (GO:0006999) | 3.28194375 |
| 35 | purine nucleobase biosynthetic process (GO:0009113) | 3.27029305 |
| 36 | ribosomal small subunit assembly (GO:0000028) | 3.25950068 |
| 37 | nucleobase biosynthetic process (GO:0046112) | 3.25694020 |
| 38 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.25204639 |
| 39 | ATP synthesis coupled proton transport (GO:0015986) | 3.25204639 |
| 40 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.24550135 |
| 41 | DNA replication-independent nucleosome organization (GO:0034724) | 3.24550135 |
| 42 | base-excision repair (GO:0006284) | 3.23655463 |
| 43 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.23624089 |
| 44 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.20960694 |
| 45 | mitotic recombination (GO:0006312) | 3.20526566 |
| 46 | rRNA modification (GO:0000154) | 3.20054276 |
| 47 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.18982362 |
| 48 | telomere maintenance via telomere lengthening (GO:0010833) | 3.17640748 |
| 49 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.17600744 |
| 50 | base-excision repair, AP site formation (GO:0006285) | 3.16489451 |
| 51 | maturation of SSU-rRNA (GO:0030490) | 3.15428133 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.13441428 |
| 53 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.13441428 |
| 54 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.13137470 |
| 55 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.11478045 |
| 56 | negative regulation of ligase activity (GO:0051352) | 3.11478045 |
| 57 | histone exchange (GO:0043486) | 3.11340363 |
| 58 | respiratory chain complex IV assembly (GO:0008535) | 3.10465169 |
| 59 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.10425894 |
| 60 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.10425894 |
| 61 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.10425894 |
| 62 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.09786197 |
| 63 | tRNA aminoacylation (GO:0043039) | 3.08089788 |
| 64 | amino acid activation (GO:0043038) | 3.08089788 |
| 65 | IMP biosynthetic process (GO:0006188) | 3.07698670 |
| 66 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.07605805 |
| 67 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.07605805 |
| 68 | tRNA aminoacylation for protein translation (GO:0006418) | 3.06994118 |
| 69 | protein complex biogenesis (GO:0070271) | 3.06597495 |
| 70 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.06319028 |
| 71 | DNA ligation (GO:0006266) | 3.04879292 |
| 72 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.04772916 |
| 73 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.04772916 |
| 74 | NADH dehydrogenase complex assembly (GO:0010257) | 3.04772916 |
| 75 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.04228251 |
| 76 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.04228251 |
| 77 | viral mRNA export from host cell nucleus (GO:0046784) | 3.02144474 |
| 78 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.01628103 |
| 79 | protein K6-linked ubiquitination (GO:0085020) | 3.01148949 |
| 80 | rRNA processing (GO:0006364) | 2.99002868 |
| 81 | protein localization to kinetochore (GO:0034501) | 2.98610003 |
| 82 | DNA replication initiation (GO:0006270) | 2.97012825 |
| 83 | transcription from mitochondrial promoter (GO:0006390) | 2.96942141 |
| 84 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.92743607 |
| 85 | mitotic metaphase plate congression (GO:0007080) | 2.92375291 |
| 86 | nuclear pore complex assembly (GO:0051292) | 2.91675715 |
| 87 | mitochondrial RNA metabolic process (GO:0000959) | 2.88868456 |
| 88 | DNA unwinding involved in DNA replication (GO:0006268) | 2.88835260 |
| 89 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.88106290 |
| 90 | non-recombinational repair (GO:0000726) | 2.88106290 |
| 91 | rRNA metabolic process (GO:0016072) | 2.88035688 |
| 92 | respiratory electron transport chain (GO:0022904) | 2.87914512 |
| 93 | translation (GO:0006412) | 2.84093160 |
| 94 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.84010447 |
| 95 | mismatch repair (GO:0006298) | 2.83730744 |
| 96 | electron transport chain (GO:0022900) | 2.81457090 |
| 97 | 7-methylguanosine mRNA capping (GO:0006370) | 2.81425421 |
| 98 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.81155062 |
| 99 | tRNA metabolic process (GO:0006399) | 2.79829736 |
| 100 | kinetochore organization (GO:0051383) | 2.79656323 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.92044430 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.73474230 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.09875514 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.00899505 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.92699507 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.77607445 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.46328884 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.35392426 |
| 9 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.24460812 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.98409321 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.91313872 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.90563807 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.86863797 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.85438366 |
| 15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.84032418 |
| 16 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.82976326 |
| 17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.76685226 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.74303212 |
| 19 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.73386540 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.67393639 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.53040388 |
| 22 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.42293789 |
| 23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.41979693 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.39707202 |
| 25 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.33588887 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.33158311 |
| 27 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.27949318 |
| 28 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.26879684 |
| 29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.23218025 |
| 30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.17175090 |
| 31 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.11514828 |
| 32 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.11502738 |
| 33 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.11205309 |
| 34 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.10593080 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.08166596 |
| 36 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04928052 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.99669511 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.95683195 |
| 39 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.94577045 |
| 40 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.91701348 |
| 41 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.91266219 |
| 42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.86877899 |
| 43 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.83811939 |
| 44 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.80210920 |
| 45 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.75732147 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.74166243 |
| 47 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.73818373 |
| 48 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.72649295 |
| 49 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.71695593 |
| 50 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.67648873 |
| 51 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.62665175 |
| 52 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.54495543 |
| 53 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.49545805 |
| 54 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.47241363 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.44669623 |
| 56 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.43736678 |
| 57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.31798690 |
| 58 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.30278089 |
| 59 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.28737653 |
| 60 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27349052 |
| 61 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.25345841 |
| 62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.25143979 |
| 63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.22333776 |
| 64 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20267374 |
| 65 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.18730370 |
| 66 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.16865719 |
| 67 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.14498685 |
| 68 | EWS_26573619_Chip-Seq_HEK293_Human | 1.10727079 |
| 69 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08327584 |
| 70 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.06871316 |
| 71 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.06231605 |
| 72 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.03414055 |
| 73 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.01679136 |
| 74 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.97706192 |
| 75 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.97261229 |
| 76 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.97057028 |
| 77 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.97006152 |
| 78 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.96486242 |
| 79 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94906267 |
| 80 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.92162968 |
| 81 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.92123575 |
| 82 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.91495186 |
| 83 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.91065186 |
| 84 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.89888764 |
| 85 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.89029276 |
| 86 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.88777051 |
| 87 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.88043927 |
| 88 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.84923652 |
| 89 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.84720397 |
| 90 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.83553335 |
| 91 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.83118814 |
| 92 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.80823014 |
| 93 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.78944877 |
| 94 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.77829189 |
| 95 | FUS_26573619_Chip-Seq_HEK293_Human | 0.76575551 |
| 96 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.74013640 |
| 97 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.72439132 |
| 98 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.71910370 |
| 99 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.71867856 |
| 100 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.70108122 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 4.52825838 |
| 2 | MP0008058_abnormal_DNA_repair | 4.18666230 |
| 3 | MP0003693_abnormal_embryo_hatching | 3.85455165 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 3.43388878 |
| 5 | MP0005171_absent_coat_pigmentation | 3.19901369 |
| 6 | MP0003111_abnormal_nucleus_morphology | 3.15001224 |
| 7 | MP0003077_abnormal_cell_cycle | 3.08930494 |
| 8 | MP0008057_abnormal_DNA_replication | 3.03413697 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.88032923 |
| 10 | MP0003941_abnormal_skin_development | 2.86157274 |
| 11 | MP0003718_maternal_effect | 2.56490922 |
| 12 | MP0008877_abnormal_DNA_methylation | 2.54833272 |
| 13 | MP0008932_abnormal_embryonic_tissue | 2.54589667 |
| 14 | MP0003786_premature_aging | 2.47844005 |
| 15 | MP0008007_abnormal_cellular_replicative | 2.42001125 |
| 16 | MP0003806_abnormal_nucleotide_metabolis | 2.30161730 |
| 17 | MP0006035_abnormal_mitochondrial_morpho | 2.17652573 |
| 18 | MP0008995_early_reproductive_senescence | 2.13493445 |
| 19 | MP0001529_abnormal_vocalization | 2.01134584 |
| 20 | MP0009697_abnormal_copulation | 1.84480131 |
| 21 | MP0008789_abnormal_olfactory_epithelium | 1.78677320 |
| 22 | MP0003136_yellow_coat_color | 1.74478761 |
| 23 | MP0006036_abnormal_mitochondrial_physio | 1.69322812 |
| 24 | MP0005257_abnormal_intraocular_pressure | 1.66593900 |
| 25 | MP0006072_abnormal_retinal_apoptosis | 1.65896202 |
| 26 | MP0000358_abnormal_cell_content/ | 1.60784690 |
| 27 | MP0003890_abnormal_embryonic-extraembry | 1.58040526 |
| 28 | MP0000516_abnormal_urinary_system | 1.45426241 |
| 29 | MP0005367_renal/urinary_system_phenotyp | 1.45426241 |
| 30 | MP0001730_embryonic_growth_arrest | 1.44582525 |
| 31 | MP0000350_abnormal_cell_proliferation | 1.42340003 |
| 32 | MP0002095_abnormal_skin_pigmentation | 1.40547637 |
| 33 | MP0000537_abnormal_urethra_morphology | 1.35700783 |
| 34 | MP0002254_reproductive_system_inflammat | 1.32855001 |
| 35 | MP0003186_abnormal_redox_activity | 1.31848066 |
| 36 | MP0005075_abnormal_melanosome_morpholog | 1.31560117 |
| 37 | MP0002938_white_spotting | 1.30435594 |
| 38 | MP0001293_anophthalmia | 1.30040294 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.27435458 |
| 40 | MP0010307_abnormal_tumor_latency | 1.25475778 |
| 41 | MP0002822_catalepsy | 1.23235608 |
| 42 | MP0006292_abnormal_olfactory_placode | 1.23122741 |
| 43 | MP0001697_abnormal_embryo_size | 1.22308912 |
| 44 | MP0002751_abnormal_autonomic_nervous | 1.21489936 |
| 45 | MP0005499_abnormal_olfactory_system | 1.21157542 |
| 46 | MP0005394_taste/olfaction_phenotype | 1.21157542 |
| 47 | MP0005380_embryogenesis_phenotype | 1.20309546 |
| 48 | MP0001672_abnormal_embryogenesis/_devel | 1.20309546 |
| 49 | MP0003315_abnormal_perineum_morphology | 1.17318694 |
| 50 | MP0000313_abnormal_cell_death | 1.17254950 |
| 51 | MP0002102_abnormal_ear_morphology | 1.15607960 |
| 52 | MP0002160_abnormal_reproductive_system | 1.13993305 |
| 53 | MP0003937_abnormal_limbs/digits/tail_de | 1.13306616 |
| 54 | MP0002210_abnormal_sex_determination | 1.12528435 |
| 55 | MP0002080_prenatal_lethality | 1.07507976 |
| 56 | MP0002396_abnormal_hematopoietic_system | 1.06730662 |
| 57 | MP0002084_abnormal_developmental_patter | 1.04728587 |
| 58 | MP0005408_hypopigmentation | 1.03770944 |
| 59 | MP0004133_heterotaxia | 1.03439106 |
| 60 | MP0001929_abnormal_gametogenesis | 1.01994229 |
| 61 | MP0001919_abnormal_reproductive_system | 1.01779755 |
| 62 | MP0003984_embryonic_growth_retardation | 1.01767199 |
| 63 | MP0002088_abnormal_embryonic_growth/wei | 1.00800814 |
| 64 | MP0001145_abnormal_male_reproductive | 0.98760232 |
| 65 | MP0002233_abnormal_nose_morphology | 0.98186109 |
| 66 | MP0002019_abnormal_tumor_incidence | 0.97904710 |
| 67 | MP0002085_abnormal_embryonic_tissue | 0.97214723 |
| 68 | MP0005389_reproductive_system_phenotype | 0.94476034 |
| 69 | MP0004197_abnormal_fetal_growth/weight/ | 0.92485781 |
| 70 | MP0000647_abnormal_sebaceous_gland | 0.92180828 |
| 71 | MP0005253_abnormal_eye_physiology | 0.90772401 |
| 72 | MP0000653_abnormal_sex_gland | 0.88927239 |
| 73 | MP0009672_abnormal_birth_weight | 0.82831281 |
| 74 | MP0000569_abnormal_digit_pigmentation | 0.81818122 |
| 75 | MP0003385_abnormal_body_wall | 0.80470615 |
| 76 | MP0002111_abnormal_tail_morphology | 0.80056827 |
| 77 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77493878 |
| 78 | MP0000015_abnormal_ear_pigmentation | 0.76144406 |
| 79 | MP0002653_abnormal_ependyma_morphology | 0.73624571 |
| 80 | MP0001324_abnormal_eye_pigmentation | 0.73114272 |
| 81 | MP0003119_abnormal_digestive_system | 0.72211140 |
| 82 | MP0009379_abnormal_foot_pigmentation | 0.71959593 |
| 83 | MP0005647_abnormal_sex_gland | 0.70922173 |
| 84 | MP0001727_abnormal_embryo_implantation | 0.69687126 |
| 85 | MP0001984_abnormal_olfaction | 0.69342523 |
| 86 | MP0001286_abnormal_eye_development | 0.67045806 |
| 87 | MP0010352_gastrointestinal_tract_polyps | 0.66706959 |
| 88 | MP0000049_abnormal_middle_ear | 0.65140818 |
| 89 | MP0002697_abnormal_eye_size | 0.65007095 |
| 90 | MP0005220_abnormal_exocrine_pancreas | 0.64614590 |
| 91 | MP0000631_abnormal_neuroendocrine_gland | 0.64359817 |
| 92 | MP0003221_abnormal_cardiomyocyte_apopto | 0.64298274 |
| 93 | MP0002163_abnormal_gland_morphology | 0.64206010 |
| 94 | MP0005391_vision/eye_phenotype | 0.64043643 |
| 95 | MP0002090_abnormal_vision | 0.63947387 |
| 96 | MP0002234_abnormal_pharynx_morphology | 0.63518782 |
| 97 | MP0002736_abnormal_nociception_after | 0.63041118 |
| 98 | MP0001119_abnormal_female_reproductive | 0.62535887 |
| 99 | MP0002177_abnormal_outer_ear | 0.62376868 |
| 100 | MP0003699_abnormal_female_reproductive | 0.61604644 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Microvesicular hepatic steatosis (HP:0001414) | 4.34946525 |
| 2 | Colon cancer (HP:0003003) | 4.24521129 |
| 3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.16092886 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.03598727 |
| 5 | Increased CSF lactate (HP:0002490) | 4.03085209 |
| 6 | Chromsome breakage (HP:0040012) | 4.02734315 |
| 7 | Mitochondrial inheritance (HP:0001427) | 4.01592634 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 4.00929332 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.65006303 |
| 10 | Acute encephalopathy (HP:0006846) | 3.57925278 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.57698112 |
| 12 | Hepatic necrosis (HP:0002605) | 3.42598333 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.31498494 |
| 14 | Reticulocytopenia (HP:0001896) | 3.13151715 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.12193497 |
| 16 | Increased serum lactate (HP:0002151) | 3.03358213 |
| 17 | Cerebral edema (HP:0002181) | 2.98274832 |
| 18 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.96478560 |
| 19 | Birth length less than 3rd percentile (HP:0003561) | 2.88651199 |
| 20 | Abnormal number of erythroid precursors (HP:0012131) | 2.88047013 |
| 21 | Type I transferrin isoform profile (HP:0003642) | 2.85787256 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 2.85738783 |
| 23 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.81624625 |
| 24 | Abnormality of chromosome stability (HP:0003220) | 2.74222854 |
| 25 | Lactic acidosis (HP:0003128) | 2.73955808 |
| 26 | Abnormality of the preputium (HP:0100587) | 2.73649861 |
| 27 | Abnormal glycosylation (HP:0012345) | 2.69377997 |
| 28 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.69377997 |
| 29 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.69377997 |
| 30 | Abnormal protein glycosylation (HP:0012346) | 2.69377997 |
| 31 | Meckel diverticulum (HP:0002245) | 2.63713808 |
| 32 | Multiple enchondromatosis (HP:0005701) | 2.61881213 |
| 33 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.58831049 |
| 34 | Abnormality of the ileum (HP:0001549) | 2.56583007 |
| 35 | Increased serum pyruvate (HP:0003542) | 2.53524113 |
| 36 | Abnormality of the labia minora (HP:0012880) | 2.51867164 |
| 37 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.47927957 |
| 38 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.47927957 |
| 39 | Increased intramyocellular lipid droplets (HP:0012240) | 2.37916379 |
| 40 | Abnormality of glycolysis (HP:0004366) | 2.37397890 |
| 41 | Respiratory failure (HP:0002878) | 2.36355822 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.34282603 |
| 43 | Renal Fanconi syndrome (HP:0001994) | 2.34034061 |
| 44 | Testicular atrophy (HP:0000029) | 2.30879862 |
| 45 | Progressive muscle weakness (HP:0003323) | 2.28898705 |
| 46 | Exercise intolerance (HP:0003546) | 2.26029431 |
| 47 | Small intestinal stenosis (HP:0012848) | 2.20538758 |
| 48 | Duodenal stenosis (HP:0100867) | 2.20538758 |
| 49 | Cleft eyelid (HP:0000625) | 2.19661027 |
| 50 | Sensory axonal neuropathy (HP:0003390) | 2.17712693 |
| 51 | Carpal bone hypoplasia (HP:0001498) | 2.17249715 |
| 52 | Methylmalonic acidemia (HP:0002912) | 2.15531250 |
| 53 | Leukodystrophy (HP:0002415) | 2.12074062 |
| 54 | Hypoplastic pelvis (HP:0008839) | 2.11931104 |
| 55 | Oral leukoplakia (HP:0002745) | 2.09097060 |
| 56 | Macrocytic anemia (HP:0001972) | 2.07194856 |
| 57 | Aplastic anemia (HP:0001915) | 2.05768026 |
| 58 | Respiratory difficulties (HP:0002880) | 2.01266897 |
| 59 | Reduced antithrombin III activity (HP:0001976) | 1.99190601 |
| 60 | Optic disc pallor (HP:0000543) | 1.98196166 |
| 61 | Triphalangeal thumb (HP:0001199) | 1.96388631 |
| 62 | Methylmalonic aciduria (HP:0012120) | 1.95252244 |
| 63 | Facial cleft (HP:0002006) | 1.93438828 |
| 64 | Esophageal atresia (HP:0002032) | 1.93000282 |
| 65 | Pancytopenia (HP:0001876) | 1.90469482 |
| 66 | Abnormality of the duodenum (HP:0002246) | 1.87998769 |
| 67 | Increased muscle lipid content (HP:0009058) | 1.87282377 |
| 68 | Patchy hypopigmentation of hair (HP:0011365) | 1.85712885 |
| 69 | Sloping forehead (HP:0000340) | 1.85119583 |
| 70 | Myelodysplasia (HP:0002863) | 1.83062421 |
| 71 | Absent radius (HP:0003974) | 1.82341539 |
| 72 | Cerebral hypomyelination (HP:0006808) | 1.81153436 |
| 73 | Bifid tongue (HP:0010297) | 1.78832399 |
| 74 | Abnormal lung lobation (HP:0002101) | 1.78460664 |
| 75 | Horseshoe kidney (HP:0000085) | 1.78287605 |
| 76 | Progressive external ophthalmoplegia (HP:0000590) | 1.77632871 |
| 77 | CNS demyelination (HP:0007305) | 1.77607584 |
| 78 | Stenosis of the external auditory canal (HP:0000402) | 1.76061890 |
| 79 | Medulloblastoma (HP:0002885) | 1.73715898 |
| 80 | Cellular immunodeficiency (HP:0005374) | 1.73066713 |
| 81 | Aplasia involving forearm bones (HP:0009822) | 1.72606596 |
| 82 | Absent forearm bone (HP:0003953) | 1.72606596 |
| 83 | Hyperglycinemia (HP:0002154) | 1.72287960 |
| 84 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.70981527 |
| 85 | Rhabdomyosarcoma (HP:0002859) | 1.69909478 |
| 86 | Premature graying of hair (HP:0002216) | 1.69370965 |
| 87 | Lethargy (HP:0001254) | 1.68485306 |
| 88 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.67241314 |
| 89 | Neoplasm of the adrenal gland (HP:0100631) | 1.65008983 |
| 90 | Sparse eyelashes (HP:0000653) | 1.64281359 |
| 91 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.64047550 |
| 92 | Emotional lability (HP:0000712) | 1.63031244 |
| 93 | Dyschromatopsia (HP:0007641) | 1.62225890 |
| 94 | Premature ovarian failure (HP:0008209) | 1.62115997 |
| 95 | Preaxial hand polydactyly (HP:0001177) | 1.61075656 |
| 96 | Renal cortical cysts (HP:0000803) | 1.60943010 |
| 97 | Abnormality of methionine metabolism (HP:0010901) | 1.60887778 |
| 98 | Neoplasm of the colon (HP:0100273) | 1.59209310 |
| 99 | Cortical dysplasia (HP:0002539) | 1.58295104 |
| 100 | Optic nerve coloboma (HP:0000588) | 1.58195525 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.72658884 |
| 2 | ZAK | 3.42199174 |
| 3 | SRPK1 | 3.37435688 |
| 4 | CDC7 | 2.96116807 |
| 5 | TTK | 2.71375198 |
| 6 | PBK | 2.59066453 |
| 7 | PLK4 | 2.42787738 |
| 8 | TLK1 | 2.39929136 |
| 9 | NME2 | 2.38286636 |
| 10 | BUB1 | 2.37863670 |
| 11 | NEK1 | 2.37533044 |
| 12 | TSSK6 | 2.36612378 |
| 13 | MST4 | 2.16011788 |
| 14 | BCKDK | 2.15143107 |
| 15 | VRK1 | 2.13469815 |
| 16 | MAP4K2 | 1.99052007 |
| 17 | WEE1 | 1.95406831 |
| 18 | ATR | 1.70632911 |
| 19 | MAP3K4 | 1.70238658 |
| 20 | PASK | 1.70053798 |
| 21 | PIM2 | 1.69514708 |
| 22 | NME1 | 1.68117004 |
| 23 | PDK2 | 1.67560385 |
| 24 | TAOK2 | 1.62941452 |
| 25 | TRIM28 | 1.59270387 |
| 26 | PLK3 | 1.56772302 |
| 27 | MKNK1 | 1.56636734 |
| 28 | PLK1 | 1.54732179 |
| 29 | WNK3 | 1.53503594 |
| 30 | MAP2K7 | 1.49724211 |
| 31 | CHEK2 | 1.49453180 |
| 32 | STK16 | 1.43784609 |
| 33 | MAP2K6 | 1.41643208 |
| 34 | NUAK1 | 1.35661682 |
| 35 | AURKB | 1.34342744 |
| 36 | EIF2AK3 | 1.32859815 |
| 37 | CSNK1G3 | 1.30879637 |
| 38 | EIF2AK1 | 1.27084143 |
| 39 | CSNK1G1 | 1.24276620 |
| 40 | CSNK1A1L | 1.20655511 |
| 41 | BRSK2 | 1.17486135 |
| 42 | BMPR1B | 1.16906445 |
| 43 | CDK7 | 1.16371129 |
| 44 | MKNK2 | 1.10959691 |
| 45 | AURKA | 1.05643172 |
| 46 | KDR | 1.03040045 |
| 47 | MAP3K10 | 0.95808469 |
| 48 | CHEK1 | 0.93628209 |
| 49 | ATM | 0.90894362 |
| 50 | TAF1 | 0.88655484 |
| 51 | CSNK1G2 | 0.87447534 |
| 52 | CDK8 | 0.86956478 |
| 53 | DYRK2 | 0.86816376 |
| 54 | BCR | 0.81769544 |
| 55 | ERBB3 | 0.79636772 |
| 56 | STK4 | 0.79458881 |
| 57 | BRSK1 | 0.77020856 |
| 58 | RPS6KA4 | 0.75585943 |
| 59 | RPS6KA5 | 0.74395808 |
| 60 | DYRK3 | 0.74021974 |
| 61 | CCNB1 | 0.73061508 |
| 62 | PINK1 | 0.72628059 |
| 63 | PIM1 | 0.70208613 |
| 64 | SCYL2 | 0.69373503 |
| 65 | CDK9 | 0.68972637 |
| 66 | STK38L | 0.68631635 |
| 67 | RPS6KB2 | 0.68547379 |
| 68 | CLK1 | 0.66596478 |
| 69 | ADRBK2 | 0.63848140 |
| 70 | CSNK2A2 | 0.62719088 |
| 71 | ERBB4 | 0.61642157 |
| 72 | TESK2 | 0.60010957 |
| 73 | CDK4 | 0.59772446 |
| 74 | CSNK2A1 | 0.59524654 |
| 75 | NLK | 0.59399215 |
| 76 | CDK1 | 0.56767551 |
| 77 | DAPK1 | 0.54352189 |
| 78 | GRK1 | 0.53061075 |
| 79 | MAP3K8 | 0.51344581 |
| 80 | CDK2 | 0.49609488 |
| 81 | FGFR1 | 0.48355847 |
| 82 | ARAF | 0.46008374 |
| 83 | NEK2 | 0.44915958 |
| 84 | PAK4 | 0.44305300 |
| 85 | GRK6 | 0.44003805 |
| 86 | DAPK3 | 0.43937006 |
| 87 | NEK6 | 0.43357709 |
| 88 | TEC | 0.42368253 |
| 89 | EIF2AK2 | 0.37019984 |
| 90 | AKT2 | 0.36611693 |
| 91 | MAP3K5 | 0.36352129 |
| 92 | EPHA3 | 0.35689018 |
| 93 | MAP3K12 | 0.34623093 |
| 94 | BRD4 | 0.34492574 |
| 95 | RAF1 | 0.32134610 |
| 96 | MAPKAPK5 | 0.32072577 |
| 97 | PRKCI | 0.31328996 |
| 98 | CDK12 | 0.30003897 |
| 99 | PRKDC | 0.29859707 |
| 100 | CSNK1E | 0.26651688 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 3.90862415 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.57914157 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.51929763 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.45375285 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 3.08860282 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 3.00319165 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.98305189 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.94703253 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.73045729 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.48790146 |
| 11 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.45173665 |
| 12 | Spliceosome_Homo sapiens_hsa03040 | 2.43924654 |
| 13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.39433180 |
| 14 | Protein export_Homo sapiens_hsa03060 | 2.25770218 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.20578787 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.19046120 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.11705716 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 2.08183595 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.98982697 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.90116276 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.77461490 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.75286720 |
| 23 | Cell cycle_Homo sapiens_hsa04110 | 1.72235781 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.61697665 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.61003444 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.57077611 |
| 27 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.57007264 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.48246903 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.42511833 |
| 30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.41351557 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.40083445 |
| 32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.32697240 |
| 33 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.32469042 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.30269853 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27187065 |
| 36 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.23138274 |
| 37 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.18308082 |
| 38 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.10202302 |
| 39 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.09925432 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.08053840 |
| 41 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.06731522 |
| 42 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.01361510 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01064983 |
| 44 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.00196164 |
| 45 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.97563875 |
| 46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.97550574 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.87501671 |
| 48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.87064551 |
| 49 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.86606128 |
| 50 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.85567433 |
| 51 | Carbon metabolism_Homo sapiens_hsa01200 | 0.82966027 |
| 52 | Sulfur relay system_Homo sapiens_hsa04122 | 0.82879922 |
| 53 | Metabolic pathways_Homo sapiens_hsa01100 | 0.77698132 |
| 54 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75600700 |
| 55 | Alcoholism_Homo sapiens_hsa05034 | 0.74298983 |
| 56 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.69847016 |
| 57 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67177111 |
| 58 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.65895571 |
| 59 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.63933941 |
| 60 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.59253637 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.56861938 |
| 62 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.56361874 |
| 63 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53975050 |
| 64 | Peroxisome_Homo sapiens_hsa04146 | 0.53403039 |
| 65 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.48189405 |
| 66 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.46111795 |
| 67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.42533580 |
| 68 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.41103789 |
| 69 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.39677500 |
| 70 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.35357087 |
| 71 | Lysine degradation_Homo sapiens_hsa00310 | 0.35309345 |
| 72 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.34313979 |
| 73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.32836803 |
| 74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32178360 |
| 75 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.27935892 |
| 76 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.24333572 |
| 77 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.24317568 |
| 78 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.20814020 |
| 79 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.20142428 |
| 80 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.19837428 |
| 81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.19806149 |
| 82 | Phototransduction_Homo sapiens_hsa04744 | 0.16867465 |
| 83 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.16690522 |
| 84 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.16249806 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.16038877 |
| 86 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.15668859 |
| 87 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.15345334 |
| 88 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.15150527 |
| 89 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.13864540 |
| 90 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.12641881 |
| 91 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.12541424 |
| 92 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.12360228 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.12076054 |
| 94 | Thyroid cancer_Homo sapiens_hsa05216 | 0.10778715 |
| 95 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.10358356 |
| 96 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.10177260 |
| 97 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.08130925 |
| 98 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.06612574 |
| 99 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.05632523 |
| 100 | Bladder cancer_Homo sapiens_hsa05219 | 0.05585569 |

