ZNF767P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.48763262
2negative regulation of cell killing (GO:0031342)5.21920231
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.21920231
4cellular extravasation (GO:0045123)5.03368018
5negative regulation of erythrocyte differentiation (GO:0045647)4.99611189
6regulation of gamma-delta T cell activation (GO:0046643)4.87774347
7regulation of gamma-delta T cell differentiation (GO:0045586)4.84030867
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.66885940
9regulation of B cell receptor signaling pathway (GO:0050855)4.50493453
10histone H3-K4 trimethylation (GO:0080182)4.37131977
11antigen processing and presentation of endogenous antigen (GO:0019883)4.36111141
12antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.34063793
13B cell receptor signaling pathway (GO:0050853)4.31089838
14positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.21610610
15antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.19734285
16negative thymic T cell selection (GO:0045060)4.12734704
17positive regulation of granulocyte differentiation (GO:0030854)4.05468398
18negative T cell selection (GO:0043383)3.96861110
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.95247864
20modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.95247864
21positive regulation by organism of defense response of other organism involved in symbiotic interact3.95247864
22modulation by symbiont of host immune response (GO:0052553)3.95247864
23positive regulation by symbiont of host defense response (GO:0052509)3.95247864
24modulation by symbiont of host defense response (GO:0052031)3.95247864
25positive regulation of B cell differentiation (GO:0045579)3.93018423
26mannose metabolic process (GO:0006013)3.84863765
27response to muramyl dipeptide (GO:0032495)3.76631541
28negative regulation of T cell mediated immunity (GO:0002710)3.72931687
29negative regulation of lymphocyte mediated immunity (GO:0002707)3.62193159
30activated T cell proliferation (GO:0050798)3.57190324
31positive thymic T cell selection (GO:0045059)3.51932584
32T cell selection (GO:0045058)3.49626015
33germinal center formation (GO:0002467)3.46738269
34detection of other organism (GO:0098543)3.46358059
35thymic T cell selection (GO:0045061)3.41593325
36macrophage activation involved in immune response (GO:0002281)3.41446791
37regulation of B cell differentiation (GO:0045577)3.39946864
38detection of bacterium (GO:0016045)3.39022246
39positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.34402835
40positive T cell selection (GO:0043368)3.30185273
41response to interleukin-15 (GO:0070672)3.29924523
42regulation of ARF protein signal transduction (GO:0032012)3.28703695
43response to peptidoglycan (GO:0032494)3.26424587
44leukocyte aggregation (GO:0070486)3.25569465
45negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.22690694
46T cell migration (GO:0072678)3.21601093
47histone H3-K9 modification (GO:0061647)3.21519354
48negative regulation of leukocyte mediated immunity (GO:0002704)3.13396773
49regulation of granulocyte differentiation (GO:0030852)3.10462614
50histone H3-K36 demethylation (GO:0070544)3.05016417
51response to host defenses (GO:0052200)3.03283108
52response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.03283108
53response to host (GO:0075136)3.03283108
54positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.02769960
55microglial cell activation (GO:0001774)2.94858666
56peptidyl-lysine trimethylation (GO:0018023)2.94371257
57detection of external biotic stimulus (GO:0098581)2.92839219
58neutrophil activation involved in immune response (GO:0002283)2.91676623
59mucosal-associated lymphoid tissue development (GO:0048537)2.90242578
60Peyers patch development (GO:0048541)2.90242578
61natural killer cell differentiation (GO:0001779)2.86895470
62response to host immune response (GO:0052572)2.85076185
63response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.85076185
64positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.83310210
65dosage compensation (GO:0007549)2.82909662
66detection of molecule of bacterial origin (GO:0032490)2.79490479
67phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.79109533
68positive regulation of myotube differentiation (GO:0010831)2.78834941
69T cell homeostasis (GO:0043029)2.77589481
70positive regulation of Rap GTPase activity (GO:0032854)2.76831507
71regulation of mast cell degranulation (GO:0043304)2.73848907
72regulation of ARF GTPase activity (GO:0032312)2.68237457
73myeloid cell activation involved in immune response (GO:0002275)2.68003093
74cellular response to interleukin-15 (GO:0071350)2.67459259
75striated muscle atrophy (GO:0014891)2.66575904
76histone H3-K9 methylation (GO:0051567)2.66193038
77positive regulation of mast cell activation (GO:0033005)2.64095745
78regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.63956070
79B cell homeostasis (GO:0001782)2.63836092
80antigen receptor-mediated signaling pathway (GO:0050851)2.63806538
81regulation of myeloid leukocyte mediated immunity (GO:0002886)2.62614292
82histone H3-K4 methylation (GO:0051568)2.61405136
83regulation of histone H3-K27 methylation (GO:0061085)2.59884681
84detection of biotic stimulus (GO:0009595)2.59439125
85negative regulation of interleukin-12 production (GO:0032695)2.58900495
86regulation of leukocyte degranulation (GO:0043300)2.58799966
87positive regulation of protein deacetylation (GO:0090312)2.57434244
88negative regulation of myotube differentiation (GO:0010832)2.54914640
89negative regulation of type 2 immune response (GO:0002829)2.54103895
90negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.53513193
91peptidyl-lysine methylation (GO:0018022)2.52204782
92histone lysine methylation (GO:0034968)2.51840696
93regulation of mast cell activation involved in immune response (GO:0033006)2.50782973
94histone H4 deacetylation (GO:0070933)2.50744083
95regulation of interferon-beta biosynthetic process (GO:0045357)2.50281029
96regulation of alpha-beta T cell proliferation (GO:0046640)2.50216854
97neutrophil mediated immunity (GO:0002446)2.50136701
98positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.49190445
99histone deubiquitination (GO:0016578)2.49016188
100lymphocyte homeostasis (GO:0002260)2.48068609

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human3.86388642
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.71195404
3MYC_22102868_ChIP-Seq_BL_Human3.65887482
4VDR_21846776_ChIP-Seq_THP-1_Human3.61840704
5SCL_19346495_ChIP-Seq_HPC-7_Human3.34199408
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.99668580
7VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.90301323
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.82796011
9KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.65119563
10SPI1_23127762_ChIP-Seq_K562_Human2.57003731
11KDM2B_26808549_Chip-Seq_DND41_Human2.56303496
12VDR_24763502_ChIP-Seq_THP-1_Human2.53342633
13TCF7_22412390_ChIP-Seq_EML_Mouse2.52990647
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.52950536
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.51880185
16E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.49695796
17MAF_26560356_Chip-Seq_TH1_Human2.49073203
18RUNX_20019798_ChIP-Seq_JUKART_Human2.48406639
19KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.35816333
20UTX_26944678_Chip-Seq_JUKART_Human2.34852755
21MAF_26560356_Chip-Seq_TH2_Human2.28803655
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.26205292
23FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.14905054
24IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.05658291
25MYB_26560356_Chip-Seq_TH2_Human2.03753759
26MYB_26560356_Chip-Seq_TH1_Human2.03012110
27GATA1_19941827_ChIP-Seq_MEL_Mouse2.01514230
28KDM2B_26808549_Chip-Seq_JURKAT_Human1.97736731
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.96739414
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.94473135
31EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.92840931
32NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.92513403
33GATA1_22025678_ChIP-Seq_K562_Human1.91501291
34MYB_21317192_ChIP-Seq_ERMYB_Mouse1.90769931
35THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.84678628
36LXR_22292898_ChIP-Seq_THP-1_Human1.83562663
37TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.83445826
38RUNX1_22412390_ChIP-Seq_EML_Mouse1.82520959
39MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.79019901
40SPI1_23547873_ChIP-Seq_NB4_Human1.77433970
41SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.76982516
42IRF8_27001747_Chip-Seq_BMDM_Mouse1.76460863
43GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.76245675
44TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73717999
45GATA1_19941826_ChIP-Seq_K562_Human1.72684812
46IRF8_21731497_ChIP-ChIP_J774_Mouse1.71308974
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69087556
48DROSHA_22980978_ChIP-Seq_HELA_Human1.61988923
49CIITA_25753668_ChIP-Seq_RAJI_Human1.60176489
50STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.55803850
51KDM2B_26808549_Chip-Seq_K562_Human1.55608040
52CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.53159908
53SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.52928849
54ELK3_25401928_ChIP-Seq_HUVEC_Human1.52830806
55GATA3_27048872_Chip-Seq_THYMUS_Human1.51934044
56NCOR1_26117541_ChIP-Seq_K562_Human1.42143922
57GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.39621159
58SMC4_20622854_ChIP-Seq_HELA_Human1.38218555
59BP1_19119308_ChIP-ChIP_Hs578T_Human1.37483661
60STAT4_19710469_ChIP-ChIP_TH1__Mouse1.35689842
61EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.31974242
62NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29749541
63GATA2_19941826_ChIP-Seq_K562_Human1.27122008
64P68_20966046_ChIP-Seq_HELA_Human1.23008092
65ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.20746522
66GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20372028
67STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19920583
68VDR_24787735_ChIP-Seq_THP-1_Human1.18569137
69DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.18539060
70IKZF1_21737484_ChIP-ChIP_HCT116_Human1.17473782
71IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.17410690
72GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17240367
73CTCF_27219007_Chip-Seq_ERYTHROID_Human1.14998736
74RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.13632352
75TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.11842347
76PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.11785563
77BCL6_27268052_Chip-Seq_Bcells_Human1.10127673
78BCOR_27268052_Chip-Seq_Bcells_Human1.09855785
79LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07278038
80SA1_27219007_Chip-Seq_ERYTHROID_Human1.07169334
81RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06260632
82GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.06202665
83LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.04186123
84CTCF_21964334_ChIP-Seq_BJAB-B_Human1.03335681
85CREB1_26743006_Chip-Seq_LNCaP_Human1.03273087
86ELF1_20517297_ChIP-Seq_JURKAT_Human1.02381455
87DNAJC2_21179169_ChIP-ChIP_NT2_Human1.00471954
88PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98155965
89PU_27001747_Chip-Seq_BMDM_Mouse0.97822500
90NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.97035187
91OCT4_19829295_ChIP-Seq_ESCs_Human0.96492853
92PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96278544
93VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95531188
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.93805059
95SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93390473
96PKCTHETA_26484144_Chip-Seq_BREAST_Human0.92730611
97GATA2_21666600_ChIP-Seq_HMVEC_Human0.92265638
98MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.91596312
99CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.91478262
100FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.90051217

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology3.57572467
2MP0003436_decreased_susceptibility_to3.28900482
3MP0001835_abnormal_antigen_presentation3.15669465
4MP0001800_abnormal_humoral_immune2.83576879
5MP0009278_abnormal_bone_marrow2.73914667
6MP0000685_abnormal_immune_system2.72534228
7MP0003303_peritoneal_inflammation2.69935910
8MP0002396_abnormal_hematopoietic_system2.59071264
9MP0003646_muscle_fatigue2.57064541
10MP0003172_abnormal_lysosome_physiology2.55206745
11MP0005000_abnormal_immune_tolerance2.43897295
12MP0005451_abnormal_body_composition2.43750803
13MP0008260_abnormal_autophagy2.41388952
14MP0004130_abnormal_muscle_cell2.37935372
15MP0002419_abnormal_innate_immunity2.37572578
16MP0002420_abnormal_adaptive_immunity2.32354314
17MP0002723_abnormal_immune_serum2.30791418
18MP0005671_abnormal_response_to2.29811849
19MP0005025_abnormal_response_to2.29769434
20MP0001819_abnormal_immune_cell2.26605820
21MP0005387_immune_system_phenotype2.24281779
22MP0001790_abnormal_immune_system2.24281779
23MP0002398_abnormal_bone_marrow2.23964494
24MP0003724_increased_susceptibility_to2.19042477
25MP0002452_abnormal_antigen_presenting2.12956341
26MP0005397_hematopoietic_system_phenotyp2.08516924
27MP0001545_abnormal_hematopoietic_system2.08516924
28MP0000703_abnormal_thymus_morphology1.98676184
29MP0000716_abnormal_immune_system1.95416115
30MP0004381_abnormal_hair_follicle1.84586820
31MP0002405_respiratory_system_inflammati1.78761455
32MP0002722_abnormal_immune_system1.69423443
33MP0000689_abnormal_spleen_morphology1.65710278
34MP0003300_gastrointestinal_ulcer1.65339841
35MP0005464_abnormal_platelet_physiology1.62169996
36MP0004947_skin_inflammation1.58817713
37MP0002429_abnormal_blood_cell1.58129742
38MP0004185_abnormal_adipocyte_glucose1.57942637
39MP0008057_abnormal_DNA_replication1.57632903
40MP0005076_abnormal_cell_differentiation1.56795227
41MP0003656_abnormal_erythrocyte_physiolo1.53762015
42MP0005666_abnormal_adipose_tissue1.46019031
43MP0003690_abnormal_glial_cell1.45489527
44MP0004808_abnormal_hematopoietic_stem1.44445454
45MP0010155_abnormal_intestine_physiology1.43551271
46MP0001851_eye_inflammation1.37454944
47MP0009333_abnormal_splenocyte_physiolog1.35811481
48MP0002933_joint_inflammation1.34599340
49MP0001873_stomach_inflammation1.31731962
50MP0003787_abnormal_imprinting1.31640165
51MP0009785_altered_susceptibility_to1.30382364
52MP0003866_abnormal_defecation1.28218856
53MP0001533_abnormal_skeleton_physiology1.26331014
54MP0002009_preneoplasia1.25962256
55MP0009115_abnormal_fat_cell1.25795581
56MP0003045_fibrosis1.23183655
57MP0005310_abnormal_salivary_gland1.19650545
58MP0005075_abnormal_melanosome_morpholog1.17757937
59MP0006082_CNS_inflammation1.15075054
60MP0002148_abnormal_hypersensitivity_rea1.12622863
61MP0002998_abnormal_bone_remodeling1.11484141
62MP0000015_abnormal_ear_pigmentation1.10149805
63MP0003828_pulmonary_edema1.09682442
64MP0001845_abnormal_inflammatory_respons1.08658471
65MP0000569_abnormal_digit_pigmentation1.07514491
66MP0004859_abnormal_synaptic_plasticity1.03449858
67MP0002132_abnormal_respiratory_system0.97201211
68MP0003191_abnormal_cellular_cholesterol0.94839990
69MP0001986_abnormal_taste_sensitivity0.94460904
70MP0008469_abnormal_protein_level0.92810628
71MP0002166_altered_tumor_susceptibility0.89745577
72MP0004036_abnormal_muscle_relaxation0.89458077
73MP0005375_adipose_tissue_phenotype0.89296832
74MP0003329_amyloid_beta_deposits0.86737832
75MP0008569_lethality_at_weaning0.84706096
76MP0001661_extended_life_span0.84542463
77MP0002971_abnormal_brown_adipose0.78329510
78MP0004883_abnormal_blood_vessel0.77112132
79MP0003091_abnormal_cell_migration0.73636082
80MP0000858_altered_metastatic_potential0.73510470
81MP0004147_increased_porphyrin_level0.72390706
82MP0002249_abnormal_larynx_morphology0.72189031
83MP0008874_decreased_physiological_sensi0.70215225
84MP0005670_abnormal_white_adipose0.70204789
85MP0005621_abnormal_cell_physiology0.67146836
86MP0000465_gastrointestinal_hemorrhage0.65729251
87MP0005409_darkened_coat_color0.65224507
88MP0004233_abnormal_muscle_weight0.64805594
89MP0000759_abnormal_skeletal_muscle0.64687192
90MP0001853_heart_inflammation0.63751498
91MP0005334_abnormal_fat_pad0.62668620
92MP0005174_abnormal_tail_pigmentation0.61980507
93MP0000604_amyloidosis0.61910655
94MP0005058_abnormal_lysosome_morphology0.60424095
95MP0003183_abnormal_peptide_metabolism0.60120017
96MP0001915_intracranial_hemorrhage0.59865206
97MP0000681_abnormal_thyroid_gland0.59263547
98MP0003879_abnormal_hair_cell0.58974616
99MP0002019_abnormal_tumor_incidence0.58862468
100MP0003705_abnormal_hypodermis_morpholog0.58130426

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)4.46234344
2Recurrent abscess formation (HP:0002722)4.19145865
3Recurrent gram-negative bacterial infections (HP:0005420)4.16812835
4Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.79787487
5Abnormality of the fingertips (HP:0001211)3.79126549
6Abnormal delayed hypersensitivity skin test (HP:0002963)3.62957295
7Papilledema (HP:0001085)3.57645448
8Recurrent bacterial skin infections (HP:0005406)3.53287183
9Colitis (HP:0002583)3.50066009
10Gingivitis (HP:0000230)3.42039122
11Myositis (HP:0100614)3.01859442
12Recurrent fungal infections (HP:0002841)3.00561020
13Panhypogammaglobulinemia (HP:0003139)3.00495410
14Gastrointestinal inflammation (HP:0004386)2.97241101
15Cellulitis (HP:0100658)2.95954234
16Spontaneous hematomas (HP:0007420)2.93187718
17Meningitis (HP:0001287)2.92794905
18Inflammation of the large intestine (HP:0002037)2.91765060
19Increased IgE level (HP:0003212)2.84766284
20Prolonged bleeding time (HP:0003010)2.81227084
21Deep palmar crease (HP:0006191)2.80975293
22Obstructive lung disease (HP:0006536)2.78979035
23Chronic obstructive pulmonary disease (HP:0006510)2.78979035
24Granulocytopenia (HP:0001913)2.71324664
25Agammaglobulinemia (HP:0004432)2.67695573
26Abnormality of macrophages (HP:0004311)2.66258180
27Mediastinal lymphadenopathy (HP:0100721)2.63691034
28Elevated erythrocyte sedimentation rate (HP:0003565)2.56076688
29Slow saccadic eye movements (HP:0000514)2.52252840
30Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.48313195
31Recurrent viral infections (HP:0004429)2.48127510
32Recurrent cutaneous fungal infections (HP:0011370)2.45428674
33Chronic mucocutaneous candidiasis (HP:0002728)2.45428674
34Hypochromic anemia (HP:0001931)2.45004341
35Exercise-induced myalgia (HP:0003738)2.44729446
36Vasculitis (HP:0002633)2.44319956
37Gastrointestinal infarctions (HP:0005244)2.43643255
38Leukocytosis (HP:0001974)2.40944747
39T lymphocytopenia (HP:0005403)2.39516857
40Abnormality of T cell number (HP:0011839)2.36585975
41Retrobulbar optic neuritis (HP:0100654)2.32019442
42Optic neuritis (HP:0100653)2.32019442
43Orchitis (HP:0100796)2.31637337
44Macroorchidism (HP:0000053)2.31287666
45Gastrointestinal stroma tumor (HP:0100723)2.30046659
46Chest pain (HP:0100749)2.29233730
47Ankle clonus (HP:0011448)2.26847991
48Recurrent skin infections (HP:0001581)2.24625045
49Obstructive sleep apnea (HP:0002870)2.24089271
50Metaphyseal cupping (HP:0003021)2.23807793
51Acute lymphatic leukemia (HP:0006721)2.22638454
52Encephalitis (HP:0002383)2.21804906
53Autoimmune hemolytic anemia (HP:0001890)2.16715974
54Genetic anticipation (HP:0003743)2.16101801
55Abnormality of the heme biosynthetic pathway (HP:0010472)2.14185355
56Hypochromic microcytic anemia (HP:0004840)2.12562973
57Heterotopia (HP:0002282)2.08717600
58Epistaxis (HP:0000421)2.08657162
59Dysmetric saccades (HP:0000641)2.04416240
60Viral hepatitis (HP:0006562)1.98591285
61Abnormality of T cells (HP:0002843)1.95617521
62Lymphopenia (HP:0001888)1.95597590
63Aplasia/Hypoplasia of the thymus (HP:0010515)1.95305840
64Pustule (HP:0200039)1.94559301
65Pulmonary infiltrates (HP:0002113)1.93677322
66Asymmetric septal hypertrophy (HP:0001670)1.92868153
67Abnormality of the left ventricular outflow tract (HP:0011103)1.92390223
68Subaortic stenosis (HP:0001682)1.92390223
69Microcytic anemia (HP:0001935)1.89376760
70Periodontitis (HP:0000704)1.88765557
71Eosinophilia (HP:0001880)1.88571756
72Recurrent bronchitis (HP:0002837)1.88110683
73Pulmonary embolism (HP:0002204)1.84533139
74Abnormality of cells of the lymphoid lineage (HP:0012140)1.84426607
75Difficulty running (HP:0009046)1.84182151
76Diplopia (HP:0000651)1.83618073
77Abnormality of binocular vision (HP:0011514)1.83618073
78Keratoconjunctivitis sicca (HP:0001097)1.82592019
79Postural instability (HP:0002172)1.82336357
80Bowel incontinence (HP:0002607)1.81570334
81Emphysema (HP:0002097)1.79457926
82Stomatitis (HP:0010280)1.79450632
83Acute myeloid leukemia (HP:0004808)1.78617933
84Osteomyelitis (HP:0002754)1.78103195
85Hemoptysis (HP:0002105)1.76173646
86Hypoplasia of the thymus (HP:0000778)1.75946314
87Abnormality of eosinophils (HP:0001879)1.75329665
88Urticaria (HP:0001025)1.75299405
89Restrictive lung disease (HP:0002091)1.74499549
90Thrombocytosis (HP:0001894)1.74459438
91Stereotypic behavior (HP:0000733)1.72705322
92Fatigue (HP:0012378)1.70716519
93Increased cerebral lipofuscin (HP:0011813)1.69723400
94Hypertensive crisis (HP:0100735)1.68439835
95Increased neuronal autofluorescent lipopigment (HP:0002074)1.68202971
96Gingival bleeding (HP:0000225)1.66494974
97Sepsis (HP:0100806)1.65384627
98Neonatal hypoglycemia (HP:0001998)1.63703032
99Basal cell carcinoma (HP:0002671)1.63292407
100Autoimmune thrombocytopenia (HP:0001973)1.61835226

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.84458584
2MAP4K13.35608808
3PRPF4B2.43971030
4TRIB32.42444947
5BLK2.23436384
6MAP2K32.17844711
7TNK22.12549915
8CDK122.12524083
9TYK22.00038362
10ZAP701.91744972
11FES1.90242687
12MARK21.87178595
13MAP3K131.80918492
14ERN11.78346536
15BTK1.70641892
16ICK1.61759888
17MAP3K71.61528740
18SIK21.60344949
19KSR21.58863948
20SYK1.58579118
21MAPK121.42271869
22CSK1.37452916
23PRKCH1.36612212
24NTRK31.33372510
25HCK1.30321867
26CDC42BPA1.25473353
27FGFR31.24970452
28EEF2K1.23384304
29TAOK31.21486534
30JAK21.21378871
31IRAK41.18185788
32JAK11.17108184
33JAK31.13784319
34FGFR41.12574003
35CSF1R1.11927059
36PDK11.11785193
37MAP3K11.11142762
38PIK3CG1.09376793
39MAP3K141.07191272
40GRK61.05685176
41LCK1.05053712
42SIK11.02840831
43SMG11.01548431
44ITK1.00237538
45MAP3K20.99928109
46KIT0.99698764
47HIPK20.99062809
48NTRK20.98296622
49MAP3K60.97664994
50RET0.94111695
51TXK0.93984537
52MAP3K110.92883037
53WNK10.91394782
54PDPK10.89232120
55TEC0.88095043
56IKBKE0.87916935
57EPHB10.85995392
58MARK30.85646361
59AKT30.83977829
60PKN20.83271457
61LYN0.82401123
62SGK30.80949576
63MAPK70.79658759
64TBK10.77564295
65STK380.76963719
66MTOR0.76674191
67STK110.74314958
68BRD40.73450211
69CDK40.72281087
70RAF10.71945539
71CAMKK10.71028546
72MAP3K100.71012318
73PRKD20.70638329
74SGK20.70477707
75MAPK110.63789888
76NLK0.61747890
77TYRO30.61437104
78RPS6KC10.60835614
79RPS6KL10.60835614
80MAP2K40.60109926
81PDGFRB0.57609372
82CAMK1D0.55321966
83TRPM70.54193415
84PIM10.53009198
85MELK0.52943258
86FGR0.51969539
87CAMK1G0.51725553
88RPS6KA60.51338031
89NTRK10.48247839
90MAP2K60.47861444
91DAPK20.47611418
92PRKD10.47007093
93SGK10.46849511
94FYN0.46782887
95RPS6KA20.46355594
96TAOK10.46223519
97TTN0.45019562
98MAPK40.44827693
99KSR10.44198267
100MAPK30.42220607

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.45452275
2Acute myeloid leukemia_Homo sapiens_hsa052212.36518589
3Fc epsilon RI signaling pathway_Homo sapiens_hsa046642.13299335
4Non-small cell lung cancer_Homo sapiens_hsa052232.08568434
5Osteoclast differentiation_Homo sapiens_hsa043801.99275497
6Chronic myeloid leukemia_Homo sapiens_hsa052201.94991744
7Leishmaniasis_Homo sapiens_hsa051401.94858935
8Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.92912513
9Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.88738368
10Phosphatidylinositol signaling system_Homo sapiens_hsa040701.79084479
11Primary immunodeficiency_Homo sapiens_hsa053401.70334407
12T cell receptor signaling pathway_Homo sapiens_hsa046601.68200157
13VEGF signaling pathway_Homo sapiens_hsa043701.63249939
14Other glycan degradation_Homo sapiens_hsa005111.62725353
15Pancreatic cancer_Homo sapiens_hsa052121.53050631
16Staphylococcus aureus infection_Homo sapiens_hsa051501.47335237
17mTOR signaling pathway_Homo sapiens_hsa041501.45677773
18Phospholipase D signaling pathway_Homo sapiens_hsa040721.44151810
19Choline metabolism in cancer_Homo sapiens_hsa052311.40174102
20Neurotrophin signaling pathway_Homo sapiens_hsa047221.36642049
21Glioma_Homo sapiens_hsa052141.36151597
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.34463790
23Graft-versus-host disease_Homo sapiens_hsa053321.33858638
24Platelet activation_Homo sapiens_hsa046111.31561285
25Tuberculosis_Homo sapiens_hsa051521.30401387
26Endometrial cancer_Homo sapiens_hsa052131.29735777
27Viral myocarditis_Homo sapiens_hsa054161.29347762
28Inositol phosphate metabolism_Homo sapiens_hsa005621.29290649
29Allograft rejection_Homo sapiens_hsa053301.27026569
30ErbB signaling pathway_Homo sapiens_hsa040121.25303279
31Autoimmune thyroid disease_Homo sapiens_hsa053201.22879991
32AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.21380156
33Prolactin signaling pathway_Homo sapiens_hsa049171.18899821
34Notch signaling pathway_Homo sapiens_hsa043301.18131521
35RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.16853801
36Chemokine signaling pathway_Homo sapiens_hsa040621.15421913
37Measles_Homo sapiens_hsa051621.15398918
38Colorectal cancer_Homo sapiens_hsa052101.13329352
39GnRH signaling pathway_Homo sapiens_hsa049121.09134766
40Renal cell carcinoma_Homo sapiens_hsa052111.08874081
41Hepatitis B_Homo sapiens_hsa051611.08653362
42Type II diabetes mellitus_Homo sapiens_hsa049301.07385207
43Toxoplasmosis_Homo sapiens_hsa051451.07144520
44Influenza A_Homo sapiens_hsa051641.06344475
45NF-kappa B signaling pathway_Homo sapiens_hsa040641.05890450
46Malaria_Homo sapiens_hsa051441.05885352
47Jak-STAT signaling pathway_Homo sapiens_hsa046301.05809551
48Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.00357999
49Carbohydrate digestion and absorption_Homo sapiens_hsa049730.99869815
50Long-term potentiation_Homo sapiens_hsa047200.97969611
51Dorso-ventral axis formation_Homo sapiens_hsa043200.97537817
52NOD-like receptor signaling pathway_Homo sapiens_hsa046210.97504889
53TNF signaling pathway_Homo sapiens_hsa046680.96087975
54FoxO signaling pathway_Homo sapiens_hsa040680.95047300
55Hepatitis C_Homo sapiens_hsa051600.94710752
56Thyroid hormone signaling pathway_Homo sapiens_hsa049190.94424701
57Hematopoietic cell lineage_Homo sapiens_hsa046400.94108921
58Herpes simplex infection_Homo sapiens_hsa051680.93824470
59Leukocyte transendothelial migration_Homo sapiens_hsa046700.93445086
60Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93374916
61Estrogen signaling pathway_Homo sapiens_hsa049150.92941902
62Longevity regulating pathway - mammal_Homo sapiens_hsa042110.92757281
63Lysine degradation_Homo sapiens_hsa003100.91666188
64Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.88825166
65Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.87722238
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.87678346
67Insulin resistance_Homo sapiens_hsa049310.87276173
68Adipocytokine signaling pathway_Homo sapiens_hsa049200.86361413
69ABC transporters_Homo sapiens_hsa020100.83893325
70Insulin signaling pathway_Homo sapiens_hsa049100.82281870
71Prostate cancer_Homo sapiens_hsa052150.80043327
72Type I diabetes mellitus_Homo sapiens_hsa049400.76624658
73MAPK signaling pathway_Homo sapiens_hsa040100.75911328
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.74506875
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.72322483
76Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67308729
77African trypanosomiasis_Homo sapiens_hsa051430.66934273
78Apoptosis_Homo sapiens_hsa042100.66120861
79Aldosterone synthesis and secretion_Homo sapiens_hsa049250.66095929
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64910889
81Amoebiasis_Homo sapiens_hsa051460.64373430
82Cholinergic synapse_Homo sapiens_hsa047250.63784884
83Viral carcinogenesis_Homo sapiens_hsa052030.62741573
84Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62631202
85Oxytocin signaling pathway_Homo sapiens_hsa049210.61382711
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.60728498
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.59913733
88Rap1 signaling pathway_Homo sapiens_hsa040150.59264521
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58551805
90Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.57819829
91Endocytosis_Homo sapiens_hsa041440.57037585
92HTLV-I infection_Homo sapiens_hsa051660.56723103
93HIF-1 signaling pathway_Homo sapiens_hsa040660.55762438
94Ras signaling pathway_Homo sapiens_hsa040140.55472012
95Small cell lung cancer_Homo sapiens_hsa052220.52867105
96Antigen processing and presentation_Homo sapiens_hsa046120.50896300
97Thyroid cancer_Homo sapiens_hsa052160.50686184
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.48994893
99Asthma_Homo sapiens_hsa053100.48142082
100Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.47250895

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