

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.93731469 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.76431014 |
| 3 | negative regulation of cell killing (GO:0031342) | 6.76431014 |
| 4 | regulation of gamma-delta T cell differentiation (GO:0045586) | 6.17407257 |
| 5 | negative T cell selection (GO:0043383) | 6.16796955 |
| 6 | negative thymic T cell selection (GO:0045060) | 5.97408054 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.94517235 |
| 8 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.81965210 |
| 9 | regulation of gamma-delta T cell activation (GO:0046643) | 5.69703169 |
| 10 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.51868751 |
| 11 | positive T cell selection (GO:0043368) | 5.42780696 |
| 12 | positive thymic T cell selection (GO:0045059) | 5.35208075 |
| 13 | response to interleukin-15 (GO:0070672) | 5.20162009 |
| 14 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.17656908 |
| 15 | thymic T cell selection (GO:0045061) | 5.07140942 |
| 16 | cellular response to interleukin-15 (GO:0071350) | 5.01862227 |
| 17 | activated T cell proliferation (GO:0050798) | 4.94454237 |
| 18 | T cell selection (GO:0045058) | 4.92033716 |
| 19 | tolerance induction (GO:0002507) | 4.81894364 |
| 20 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.73476475 |
| 21 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.66746430 |
| 22 | negative regulation of T cell mediated immunity (GO:0002710) | 4.52027849 |
| 23 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.46316967 |
| 24 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.40706849 |
| 25 | interferon-gamma production (GO:0032609) | 4.39765663 |
| 26 | leukocyte aggregation (GO:0070486) | 4.38914137 |
| 27 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.32616004 |
| 28 | positive regulation of granulocyte differentiation (GO:0030854) | 4.14226175 |
| 29 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 4.11274670 |
| 30 | T cell migration (GO:0072678) | 4.10993128 |
| 31 | regulation of regulatory T cell differentiation (GO:0045589) | 4.07963558 |
| 32 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.00740997 |
| 33 | B cell receptor signaling pathway (GO:0050853) | 3.87239833 |
| 34 | regulation of B cell differentiation (GO:0045577) | 3.83267900 |
| 35 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.77827802 |
| 36 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.77802455 |
| 37 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.70262249 |
| 38 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.69464108 |
| 39 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.69464108 |
| 40 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.69313025 |
| 41 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.65131634 |
| 42 | Peyers patch development (GO:0048541) | 3.65131634 |
| 43 | regulation of T cell tolerance induction (GO:0002664) | 3.62467831 |
| 44 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.60546744 |
| 45 | T cell receptor signaling pathway (GO:0050852) | 3.58887257 |
| 46 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.53910286 |
| 47 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.52943142 |
| 48 | lymph node development (GO:0048535) | 3.48885167 |
| 49 | positive regulation of B cell differentiation (GO:0045579) | 3.46618125 |
| 50 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.45930266 |
| 51 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.42971170 |
| 52 | negative regulation of adaptive immune response (GO:0002820) | 3.35346342 |
| 53 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.34878373 |
| 54 | T cell homeostasis (GO:0043029) | 3.28067792 |
| 55 | negative regulation of B cell mediated immunity (GO:0002713) | 3.27365540 |
| 56 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.27365540 |
| 57 | positive regulation of interleukin-2 production (GO:0032743) | 3.26395948 |
| 58 | mast cell activation (GO:0045576) | 3.25697573 |
| 59 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.25394366 |
| 60 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.25145593 |
| 61 | alpha-beta T cell differentiation (GO:0046632) | 3.23146757 |
| 62 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.22500928 |
| 63 | detection of bacterium (GO:0016045) | 3.20975124 |
| 64 | detection of other organism (GO:0098543) | 3.19859252 |
| 65 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.17153656 |
| 66 | regulation of granulocyte differentiation (GO:0030852) | 3.15236053 |
| 67 | regulation of tolerance induction (GO:0002643) | 3.12868978 |
| 68 | positive regulation of tolerance induction (GO:0002645) | 3.12093691 |
| 69 | histone H3-K36 demethylation (GO:0070544) | 3.11372814 |
| 70 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.05266671 |
| 71 | positive regulation of isotype switching (GO:0045830) | 3.02708629 |
| 72 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.01919237 |
| 73 | cellular extravasation (GO:0045123) | 2.99019277 |
| 74 | alpha-beta T cell activation (GO:0046631) | 2.97888906 |
| 75 | regulation of cell killing (GO:0031341) | 2.97839249 |
| 76 | natural killer cell differentiation (GO:0001779) | 2.97203873 |
| 77 | positive regulation of humoral immune response (GO:0002922) | 2.96683550 |
| 78 | negative regulation of innate immune response (GO:0045824) | 2.95873887 |
| 79 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.94304211 |
| 80 | positive regulation of cell killing (GO:0031343) | 2.92397820 |
| 81 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.91904277 |
| 82 | modulation by symbiont of host immune response (GO:0052553) | 2.91904277 |
| 83 | positive regulation by symbiont of host defense response (GO:0052509) | 2.91904277 |
| 84 | modulation by symbiont of host defense response (GO:0052031) | 2.91904277 |
| 85 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.91904277 |
| 86 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.91904277 |
| 87 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.91328410 |
| 88 | mast cell degranulation (GO:0043303) | 2.90903925 |
| 89 | mast cell activation involved in immune response (GO:0002279) | 2.90903925 |
| 90 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.90837623 |
| 91 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.89172862 |
| 92 | regulation of alpha-beta T cell activation (GO:0046634) | 2.87868638 |
| 93 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.87132198 |
| 94 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.85532499 |
| 95 | response to laminar fluid shear stress (GO:0034616) | 2.84870696 |
| 96 | T cell proliferation (GO:0042098) | 2.81990391 |
| 97 | T cell differentiation (GO:0030217) | 2.78940325 |
| 98 | T cell costimulation (GO:0031295) | 2.78103885 |
| 99 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.78001137 |
| 100 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.78001137 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.43113331 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.03943564 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.30295650 |
| 4 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.40800825 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.34871387 |
| 6 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.27784710 |
| 7 | MAF_26560356_Chip-Seq_TH1_Human | 3.23450003 |
| 8 | MYC_22102868_ChIP-Seq_BL_Human | 3.22535677 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.04044153 |
| 10 | UTX_26944678_Chip-Seq_JUKART_Human | 2.94551126 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.93088081 |
| 12 | MAF_26560356_Chip-Seq_TH2_Human | 2.87278746 |
| 13 | MYB_26560356_Chip-Seq_TH1_Human | 2.62622152 |
| 14 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.57793739 |
| 15 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.55874708 |
| 16 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.54156415 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.52555110 |
| 18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.48210897 |
| 19 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.45416571 |
| 20 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.42967795 |
| 21 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.39657307 |
| 22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.35920613 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.31455954 |
| 24 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.20687291 |
| 25 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.20519219 |
| 26 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.20116323 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.19015769 |
| 28 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.17045380 |
| 29 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.12382036 |
| 30 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.03921642 |
| 31 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.95859955 |
| 32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.94955458 |
| 33 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.93573639 |
| 34 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92024762 |
| 35 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.88938127 |
| 36 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.86239606 |
| 37 | GATA1_22025678_ChIP-Seq_K562_Human | 1.85698501 |
| 38 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.85085175 |
| 39 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.84312822 |
| 40 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.79874518 |
| 41 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.70513285 |
| 42 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.68610698 |
| 43 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.58795352 |
| 44 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57777007 |
| 45 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.57412384 |
| 46 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.55932954 |
| 47 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.49216404 |
| 48 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.47685587 |
| 49 | GATA3_26560356_Chip-Seq_TH2_Human | 1.44242969 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.41212636 |
| 51 | SPI1_23127762_ChIP-Seq_K562_Human | 1.40077673 |
| 52 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34098799 |
| 53 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.31644650 |
| 54 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.31422567 |
| 55 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.31287122 |
| 56 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.29070734 |
| 57 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.28755418 |
| 58 | P68_20966046_ChIP-Seq_HELA_Human | 1.27372322 |
| 59 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.23734466 |
| 60 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.23065407 |
| 61 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.22530050 |
| 62 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.19416237 |
| 63 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.16627032 |
| 64 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.16351795 |
| 65 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.15664964 |
| 66 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.15658499 |
| 67 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.15439064 |
| 68 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.14892489 |
| 69 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14423443 |
| 70 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.12039459 |
| 71 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.10080368 |
| 72 | GATA1_19941826_ChIP-Seq_K562_Human | 1.09437792 |
| 73 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.07936956 |
| 74 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.07624474 |
| 75 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.07622106 |
| 76 | * SMC4_20622854_ChIP-Seq_HELA_Human | 1.07555879 |
| 77 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.05881287 |
| 78 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.04990483 |
| 79 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.04061796 |
| 80 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03447544 |
| 81 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.02168676 |
| 82 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.01723092 |
| 83 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.01676332 |
| 84 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00232247 |
| 85 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99284024 |
| 86 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.99073247 |
| 87 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.98008171 |
| 88 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.97055340 |
| 89 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.96701524 |
| 90 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.96546178 |
| 91 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.94827689 |
| 92 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.94757090 |
| 93 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93193935 |
| 94 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.93188887 |
| 95 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.90144421 |
| 96 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.89765893 |
| 97 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.89242533 |
| 98 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.89067961 |
| 99 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.87118126 |
| 100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84877208 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.95713138 |
| 2 | MP0005083_abnormal_biliary_tract | 3.79499981 |
| 3 | MP0005671_abnormal_response_to | 3.58132716 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.28423359 |
| 5 | MP0003436_decreased_susceptibility_to | 3.16087208 |
| 6 | MP0001800_abnormal_humoral_immune | 3.15111717 |
| 7 | MP0003724_increased_susceptibility_to | 3.00401770 |
| 8 | MP0004381_abnormal_hair_follicle | 2.87770378 |
| 9 | MP0009333_abnormal_splenocyte_physiolog | 2.74389699 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.73962175 |
| 11 | MP0002723_abnormal_immune_serum | 2.65366807 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.55397856 |
| 13 | MP0001819_abnormal_immune_cell | 2.51147306 |
| 14 | MP0001986_abnormal_taste_sensitivity | 2.43628858 |
| 15 | MP0001790_abnormal_immune_system | 2.43008603 |
| 16 | MP0005387_immune_system_phenotype | 2.43008603 |
| 17 | MP0002398_abnormal_bone_marrow | 2.40997276 |
| 18 | MP0000685_abnormal_immune_system | 2.40341901 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.35448563 |
| 20 | MP0000703_abnormal_thymus_morphology | 2.34146049 |
| 21 | MP0005174_abnormal_tail_pigmentation | 2.27252600 |
| 22 | MP0005025_abnormal_response_to | 2.25238055 |
| 23 | MP0001873_stomach_inflammation | 2.17353118 |
| 24 | MP0000716_abnormal_immune_system | 2.13810735 |
| 25 | MP0002405_respiratory_system_inflammati | 2.13450650 |
| 26 | MP0002419_abnormal_innate_immunity | 2.08685102 |
| 27 | MP0003303_peritoneal_inflammation | 2.01441796 |
| 28 | MP0000689_abnormal_spleen_morphology | 1.98903462 |
| 29 | MP0002009_preneoplasia | 1.93405421 |
| 30 | MP0002722_abnormal_immune_system | 1.92487225 |
| 31 | MP0010155_abnormal_intestine_physiology | 1.84094877 |
| 32 | MP0006082_CNS_inflammation | 1.78301839 |
| 33 | MP0009785_altered_susceptibility_to | 1.77407652 |
| 34 | MP0002396_abnormal_hematopoietic_system | 1.77147991 |
| 35 | MP0003866_abnormal_defecation | 1.75430359 |
| 36 | MP0002429_abnormal_blood_cell | 1.74327302 |
| 37 | MP0002148_abnormal_hypersensitivity_rea | 1.72392160 |
| 38 | MP0004947_skin_inflammation | 1.59586547 |
| 39 | MP0002166_altered_tumor_susceptibility | 1.57482611 |
| 40 | MP0004130_abnormal_muscle_cell | 1.57371001 |
| 41 | MP0000015_abnormal_ear_pigmentation | 1.49866689 |
| 42 | MP0003300_gastrointestinal_ulcer | 1.48589434 |
| 43 | MP0001348_abnormal_lacrimal_gland | 1.47210580 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.44177590 |
| 45 | MP0000569_abnormal_digit_pigmentation | 1.37776910 |
| 46 | MP0008057_abnormal_DNA_replication | 1.36942326 |
| 47 | MP0005310_abnormal_salivary_gland | 1.36203291 |
| 48 | MP0002933_joint_inflammation | 1.33569229 |
| 49 | MP0005171_absent_coat_pigmentation | 1.33265153 |
| 50 | MP0004808_abnormal_hematopoietic_stem | 1.29793075 |
| 51 | MP0005464_abnormal_platelet_physiology | 1.18435037 |
| 52 | MP0001851_eye_inflammation | 1.14734824 |
| 53 | MP0001533_abnormal_skeleton_physiology | 1.13735189 |
| 54 | MP0008469_abnormal_protein_level | 1.13169819 |
| 55 | MP0009278_abnormal_bone_marrow | 1.13109036 |
| 56 | MP0000465_gastrointestinal_hemorrhage | 1.13021854 |
| 57 | MP0005423_abnormal_somatic_nervous | 1.11170735 |
| 58 | MP0002019_abnormal_tumor_incidence | 1.03198755 |
| 59 | MP0005076_abnormal_cell_differentiation | 1.01066234 |
| 60 | MP0000858_altered_metastatic_potential | 0.97099238 |
| 61 | MP0003172_abnormal_lysosome_physiology | 0.96578950 |
| 62 | MP0002006_tumorigenesis | 0.95535791 |
| 63 | MP0005075_abnormal_melanosome_morpholog | 0.95258050 |
| 64 | MP0008260_abnormal_autophagy | 0.95009211 |
| 65 | MP0003091_abnormal_cell_migration | 0.90841779 |
| 66 | MP0003448_altered_tumor_morphology | 0.88912163 |
| 67 | MP0000490_abnormal_crypts_of | 0.86036070 |
| 68 | MP0005451_abnormal_body_composition | 0.81942572 |
| 69 | MP0003828_pulmonary_edema | 0.78778108 |
| 70 | MP0002277_abnormal_respiratory_mucosa | 0.78515310 |
| 71 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.76924208 |
| 72 | MP0002998_abnormal_bone_remodeling | 0.75953103 |
| 73 | MP0001853_heart_inflammation | 0.75449942 |
| 74 | MP0008961_abnormal_basal_metabolism | 0.74802883 |
| 75 | MP0003453_abnormal_keratinocyte_physiol | 0.73744964 |
| 76 | MP0003136_yellow_coat_color | 0.72461988 |
| 77 | MP0002132_abnormal_respiratory_system | 0.69656803 |
| 78 | MP0003656_abnormal_erythrocyte_physiolo | 0.68805545 |
| 79 | MP0003183_abnormal_peptide_metabolism | 0.68476318 |
| 80 | MP0004883_abnormal_blood_vessel | 0.67718449 |
| 81 | MP0003045_fibrosis | 0.65869991 |
| 82 | MP0002928_abnormal_bile_duct | 0.61868882 |
| 83 | MP0001663_abnormal_digestive_system | 0.60257183 |
| 84 | MP0005085_abnormal_gallbladder_physiolo | 0.59766062 |
| 85 | MP0001919_abnormal_reproductive_system | 0.59206793 |
| 86 | MP0002136_abnormal_kidney_physiology | 0.59094579 |
| 87 | MP0005409_darkened_coat_color | 0.59035302 |
| 88 | MP0001765_abnormal_ion_homeostasis | 0.57745108 |
| 89 | MP0009764_decreased_sensitivity_to | 0.57635024 |
| 90 | MP0009763_increased_sensitivity_to | 0.57122809 |
| 91 | MP0000003_abnormal_adipose_tissue | 0.56695310 |
| 92 | MP0008874_decreased_physiological_sensi | 0.56687654 |
| 93 | MP0000249_abnormal_blood_vessel | 0.55631606 |
| 94 | MP0002693_abnormal_pancreas_physiology | 0.54271937 |
| 95 | MP0002138_abnormal_hepatobiliary_system | 0.51991224 |
| 96 | MP0000367_abnormal_coat/_hair | 0.51930315 |
| 97 | MP0001661_extended_life_span | 0.49404745 |
| 98 | MP0002638_abnormal_pupillary_reflex | 0.49005263 |
| 99 | MP0003077_abnormal_cell_cycle | 0.48737304 |
| 100 | MP0004484_altered_response_of | 0.48073373 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 5.73285241 |
| 2 | Abnormality of T cell number (HP:0011839) | 5.27592097 |
| 3 | Eczematoid dermatitis (HP:0000976) | 4.73745958 |
| 4 | Pustule (HP:0200039) | 4.51756683 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.46692831 |
| 6 | Myositis (HP:0100614) | 4.21478815 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 4.06031358 |
| 8 | Recurrent fungal infections (HP:0002841) | 4.05952054 |
| 9 | Abnormality of T cells (HP:0002843) | 4.04161544 |
| 10 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.98370129 |
| 11 | Stomatitis (HP:0010280) | 3.86345607 |
| 12 | Recurrent abscess formation (HP:0002722) | 3.80719157 |
| 13 | Gastrointestinal infarctions (HP:0005244) | 3.63487596 |
| 14 | Panhypogammaglobulinemia (HP:0003139) | 3.62472830 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 3.53122516 |
| 16 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.41978387 |
| 17 | Recurrent cutaneous fungal infections (HP:0011370) | 3.41978387 |
| 18 | Optic neuritis (HP:0100653) | 3.37729120 |
| 19 | Retrobulbar optic neuritis (HP:0100654) | 3.37729120 |
| 20 | Orchitis (HP:0100796) | 3.30955959 |
| 21 | Recurrent viral infections (HP:0004429) | 3.17512208 |
| 22 | Meningitis (HP:0001287) | 3.15665783 |
| 23 | IgG deficiency (HP:0004315) | 3.12674947 |
| 24 | Encephalitis (HP:0002383) | 3.09323049 |
| 25 | Abnormality of eosinophils (HP:0001879) | 3.08755108 |
| 26 | Inflammation of the large intestine (HP:0002037) | 3.04602641 |
| 27 | Autoimmune hemolytic anemia (HP:0001890) | 3.01930132 |
| 28 | Colitis (HP:0002583) | 3.01770855 |
| 29 | Recurrent skin infections (HP:0001581) | 3.01259236 |
| 30 | Basal cell carcinoma (HP:0002671) | 2.97973282 |
| 31 | Spontaneous hematomas (HP:0007420) | 2.95284748 |
| 32 | IgM deficiency (HP:0002850) | 2.95204751 |
| 33 | Abnormality of macrophages (HP:0004311) | 2.93551781 |
| 34 | Gastrointestinal inflammation (HP:0004386) | 2.88536662 |
| 35 | Recurrent bronchitis (HP:0002837) | 2.84620264 |
| 36 | Vasculitis (HP:0002633) | 2.84359826 |
| 37 | Abnormality of T cell physiology (HP:0011840) | 2.81386361 |
| 38 | Leukocytosis (HP:0001974) | 2.76432358 |
| 39 | Abnormality of the fingertips (HP:0001211) | 2.76264283 |
| 40 | Granulocytopenia (HP:0001913) | 2.76167509 |
| 41 | Hypochromic anemia (HP:0001931) | 2.73211864 |
| 42 | Mediastinal lymphadenopathy (HP:0100721) | 2.71718743 |
| 43 | Poikiloderma (HP:0001029) | 2.69910104 |
| 44 | Combined immunodeficiency (HP:0005387) | 2.69621421 |
| 45 | Lymphopenia (HP:0001888) | 2.67193447 |
| 46 | Hypoplasia of the thymus (HP:0000778) | 2.65382749 |
| 47 | Eosinophilia (HP:0001880) | 2.61711325 |
| 48 | Anorexia (HP:0002039) | 2.56092372 |
| 49 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.55176442 |
| 50 | Chest pain (HP:0100749) | 2.54877129 |
| 51 | Dyschromatopsia (HP:0007641) | 2.50250228 |
| 52 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.49292292 |
| 53 | Abnormality of the nasal septum (HP:0000419) | 2.48854990 |
| 54 | Obstructive lung disease (HP:0006536) | 2.44102543 |
| 55 | Chronic obstructive pulmonary disease (HP:0006510) | 2.44102543 |
| 56 | Pulmonary infiltrates (HP:0002113) | 2.39743197 |
| 57 | Epistaxis (HP:0000421) | 2.39484174 |
| 58 | Premature graying of hair (HP:0002216) | 2.37228112 |
| 59 | Keratoconjunctivitis sicca (HP:0001097) | 2.36366442 |
| 60 | Prolonged bleeding time (HP:0003010) | 2.36138794 |
| 61 | Lymphoma (HP:0002665) | 2.36107584 |
| 62 | Testicular atrophy (HP:0000029) | 2.33851600 |
| 63 | Increased IgE level (HP:0003212) | 2.33470224 |
| 64 | Keratoconjunctivitis (HP:0001096) | 2.32361281 |
| 65 | Slow saccadic eye movements (HP:0000514) | 2.31667023 |
| 66 | Verrucae (HP:0200043) | 2.28603351 |
| 67 | Papilloma (HP:0012740) | 2.28603351 |
| 68 | Papilledema (HP:0001085) | 2.26551345 |
| 69 | Acute hepatic failure (HP:0006554) | 2.25405764 |
| 70 | Agammaglobulinemia (HP:0004432) | 2.21569669 |
| 71 | Attenuation of retinal blood vessels (HP:0007843) | 2.19523318 |
| 72 | Increased IgM level (HP:0003496) | 2.17800211 |
| 73 | Chronic diarrhea (HP:0002028) | 2.16819020 |
| 74 | Hemoptysis (HP:0002105) | 2.15922207 |
| 75 | Dislocated radial head (HP:0003083) | 2.15439799 |
| 76 | Facial diplegia (HP:0001349) | 2.15023225 |
| 77 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.12981324 |
| 78 | Annular pancreas (HP:0001734) | 2.12373138 |
| 79 | Thyroiditis (HP:0100646) | 2.10131244 |
| 80 | Rib fusion (HP:0000902) | 2.09921711 |
| 81 | Lip pit (HP:0100267) | 2.08146138 |
| 82 | IgA deficiency (HP:0002720) | 2.06700548 |
| 83 | Hypoalbuminemia (HP:0003073) | 2.05378102 |
| 84 | Abnormal albumin level (HP:0012116) | 2.05378102 |
| 85 | Arterial thrombosis (HP:0004420) | 2.01470801 |
| 86 | Autoimmune thrombocytopenia (HP:0001973) | 1.98950806 |
| 87 | Thin bony cortex (HP:0002753) | 1.98685800 |
| 88 | Abnormality of B cell number (HP:0010975) | 1.96604199 |
| 89 | Abnormality of the radial head (HP:0003995) | 1.94786689 |
| 90 | Gingivitis (HP:0000230) | 1.93665468 |
| 91 | Prominent nose (HP:0000448) | 1.89187523 |
| 92 | Viral hepatitis (HP:0006562) | 1.84931647 |
| 93 | Cellulitis (HP:0100658) | 1.82878648 |
| 94 | Short chin (HP:0000331) | 1.81799358 |
| 95 | Pulmonary embolism (HP:0002204) | 1.79773525 |
| 96 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.79245852 |
| 97 | Intestinal fistula (HP:0100819) | 1.79097482 |
| 98 | Joint hemorrhage (HP:0005261) | 1.79059327 |
| 99 | Subacute progressive viral hepatitis (HP:0006572) | 1.77981314 |
| 100 | Squamous cell carcinoma (HP:0002860) | 1.76686330 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 4.53303249 |
| 2 | TXK | 3.84583725 |
| 3 | PDK2 | 3.24092992 |
| 4 | RIPK4 | 2.96758754 |
| 5 | GRK6 | 2.83049843 |
| 6 | BLK | 2.68139303 |
| 7 | PRPF4B | 2.56166115 |
| 8 | ZAP70 | 2.26835738 |
| 9 | BTK | 2.18831720 |
| 10 | CSK | 2.16283826 |
| 11 | FES | 2.07516056 |
| 12 | TYK2 | 1.95956278 |
| 13 | ITK | 1.95228707 |
| 14 | IKBKE | 1.77291664 |
| 15 | TAOK3 | 1.71922195 |
| 16 | JAK3 | 1.71204967 |
| 17 | MAPK15 | 1.67353144 |
| 18 | MAP2K3 | 1.63787151 |
| 19 | TESK2 | 1.63685237 |
| 20 | SYK | 1.62400925 |
| 21 | TLK1 | 1.60992093 |
| 22 | MAP3K10 | 1.60806880 |
| 23 | WNK4 | 1.56482655 |
| 24 | NEK6 | 1.52654133 |
| 25 | MAP3K13 | 1.48854742 |
| 26 | JAK1 | 1.45931190 |
| 27 | CAMKK2 | 1.44519887 |
| 28 | ERN1 | 1.42436240 |
| 29 | TNK2 | 1.41813260 |
| 30 | LCK | 1.40265025 |
| 31 | HCK | 1.38737714 |
| 32 | SIK2 | 1.34859782 |
| 33 | PIM1 | 1.34411679 |
| 34 | IRAK4 | 1.33090831 |
| 35 | CDK12 | 1.32799973 |
| 36 | NLK | 1.29461886 |
| 37 | MAPK12 | 1.26461589 |
| 38 | MAP3K14 | 1.25228403 |
| 39 | MARK3 | 1.20511094 |
| 40 | TEC | 1.14073845 |
| 41 | SIK3 | 1.10726150 |
| 42 | BMPR2 | 1.10303485 |
| 43 | LYN | 1.08780751 |
| 44 | RAF1 | 1.08183450 |
| 45 | MAPK11 | 1.06431873 |
| 46 | CDK4 | 1.05856719 |
| 47 | MAPK7 | 1.01980737 |
| 48 | PDK1 | 1.01908529 |
| 49 | CAMKK1 | 1.01220259 |
| 50 | IKBKB | 0.99463521 |
| 51 | PRKCQ | 0.94188329 |
| 52 | EPHB1 | 0.94113541 |
| 53 | PASK | 0.93043859 |
| 54 | MELK | 0.92001177 |
| 55 | TBK1 | 0.90523180 |
| 56 | MAP3K1 | 0.90115827 |
| 57 | MARK2 | 0.87791936 |
| 58 | FGFR3 | 0.87117989 |
| 59 | PDPK1 | 0.85727903 |
| 60 | JAK2 | 0.85005101 |
| 61 | STK10 | 0.81683559 |
| 62 | STK11 | 0.80667897 |
| 63 | MAP3K3 | 0.76767281 |
| 64 | FGFR4 | 0.75720504 |
| 65 | ACVR1B | 0.73563890 |
| 66 | HIPK2 | 0.72366679 |
| 67 | CDK6 | 0.71778049 |
| 68 | ICK | 0.69882008 |
| 69 | TRIB3 | 0.69574067 |
| 70 | MAP3K7 | 0.68974624 |
| 71 | TYRO3 | 0.64677244 |
| 72 | BRD4 | 0.63814491 |
| 73 | STK39 | 0.62944265 |
| 74 | MAP3K11 | 0.61037953 |
| 75 | MUSK | 0.59532031 |
| 76 | TGFBR2 | 0.58062368 |
| 77 | KSR2 | 0.56800434 |
| 78 | OXSR1 | 0.55454794 |
| 79 | YES1 | 0.55425171 |
| 80 | PIK3CG | 0.55123124 |
| 81 | MAP2K6 | 0.51763644 |
| 82 | SIK1 | 0.51295829 |
| 83 | WNK1 | 0.50683873 |
| 84 | PIM2 | 0.49980561 |
| 85 | TAOK1 | 0.47399827 |
| 86 | MAP2K2 | 0.44566586 |
| 87 | SMG1 | 0.40999430 |
| 88 | PDGFRB | 0.40925137 |
| 89 | STK38 | 0.40834131 |
| 90 | ZAK | 0.39058623 |
| 91 | CSF1R | 0.38049452 |
| 92 | FGR | 0.37430168 |
| 93 | TAOK2 | 0.37291474 |
| 94 | RPS6KA6 | 0.33824467 |
| 95 | DYRK1B | 0.33296045 |
| 96 | FYN | 0.33219341 |
| 97 | PTK6 | 0.32732747 |
| 98 | CAMK4 | 0.32305716 |
| 99 | RPS6KC1 | 0.32033784 |
| 100 | RPS6KL1 | 0.32033784 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.14922153 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.99970052 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.57017783 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.49866159 |
| 5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.31798553 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.30846384 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.30264080 |
| 8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.19841705 |
| 9 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.15440911 |
| 10 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.12347083 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.08441425 |
| 12 | Measles_Homo sapiens_hsa05162 | 1.98019728 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.91512243 |
| 14 | Leishmaniasis_Homo sapiens_hsa05140 | 1.76677268 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.73642975 |
| 16 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.73441003 |
| 17 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.70524037 |
| 18 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.67588412 |
| 19 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.62454011 |
| 20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.52138880 |
| 21 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.51662059 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.49443283 |
| 23 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.46604928 |
| 24 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.46208975 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.44414820 |
| 26 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.41361711 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.34012012 |
| 28 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.32804826 |
| 29 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.30128878 |
| 30 | Hepatitis B_Homo sapiens_hsa05161 | 1.27906747 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.27314904 |
| 32 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.25303589 |
| 33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.25239314 |
| 34 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.22264717 |
| 35 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.21859761 |
| 36 | Tuberculosis_Homo sapiens_hsa05152 | 1.21591689 |
| 37 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.16743247 |
| 38 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.12025273 |
| 39 | Influenza A_Homo sapiens_hsa05164 | 1.10584087 |
| 40 | Apoptosis_Homo sapiens_hsa04210 | 1.07293576 |
| 41 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.07231291 |
| 42 | Platelet activation_Homo sapiens_hsa04611 | 1.04677867 |
| 43 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.03332475 |
| 44 | Circadian rhythm_Homo sapiens_hsa04710 | 1.02064466 |
| 45 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.99433788 |
| 46 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.97697235 |
| 47 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.96802110 |
| 48 | HTLV-I infection_Homo sapiens_hsa05166 | 0.96748756 |
| 49 | Colorectal cancer_Homo sapiens_hsa05210 | 0.93207838 |
| 50 | Malaria_Homo sapiens_hsa05144 | 0.92643972 |
| 51 | Endometrial cancer_Homo sapiens_hsa05213 | 0.92361731 |
| 52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.90924677 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.89532571 |
| 54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.87552583 |
| 55 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.85288738 |
| 56 | Hepatitis C_Homo sapiens_hsa05160 | 0.80595541 |
| 57 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.80062297 |
| 58 | Sulfur relay system_Homo sapiens_hsa04122 | 0.79816662 |
| 59 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.72050783 |
| 60 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.71310760 |
| 61 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.70572028 |
| 62 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.70283075 |
| 63 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.68597771 |
| 64 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.66896867 |
| 65 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65362078 |
| 66 | Asthma_Homo sapiens_hsa05310 | 0.65355913 |
| 67 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.64733039 |
| 68 | Other glycan degradation_Homo sapiens_hsa00511 | 0.64107565 |
| 69 | Insulin resistance_Homo sapiens_hsa04931 | 0.63978771 |
| 70 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63890067 |
| 71 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.62867575 |
| 72 | Thyroid cancer_Homo sapiens_hsa05216 | 0.62292558 |
| 73 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61015306 |
| 74 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.59735509 |
| 75 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.56271735 |
| 76 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.55988691 |
| 77 | Endocytosis_Homo sapiens_hsa04144 | 0.54684197 |
| 78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.54165517 |
| 79 | Legionellosis_Homo sapiens_hsa05134 | 0.52469881 |
| 80 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.52102647 |
| 81 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.51940427 |
| 82 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.51830099 |
| 83 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.46370962 |
| 84 | Pertussis_Homo sapiens_hsa05133 | 0.45546014 |
| 85 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.45341916 |
| 86 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.44696351 |
| 87 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.44290558 |
| 88 | Prostate cancer_Homo sapiens_hsa05215 | 0.44100026 |
| 89 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.42828645 |
| 90 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.42383981 |
| 91 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.41877921 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.41544582 |
| 93 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.40400159 |
| 94 | Shigellosis_Homo sapiens_hsa05131 | 0.40321504 |
| 95 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.38242442 |
| 96 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.38232903 |
| 97 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.38146486 |
| 98 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.38110563 |
| 99 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.37630522 |
| 100 | Long-term potentiation_Homo sapiens_hsa04720 | 0.37576799 |

