ZNF833P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1centriole replication (GO:0007099)5.08723579
2negative regulation of retinoic acid receptor signaling pathway (GO:0048387)4.95314138
3microtubule depolymerization (GO:0007019)4.76531999
4regulation of DNA endoreduplication (GO:0032875)4.74288354
5CENP-A containing nucleosome assembly (GO:0034080)4.55393648
6chromatin remodeling at centromere (GO:0031055)4.54604838
7epithelial cilium movement (GO:0003351)4.52545238
8mitotic metaphase plate congression (GO:0007080)4.50398636
9mitotic chromosome condensation (GO:0007076)4.37461140
10axonemal dynein complex assembly (GO:0070286)4.37308221
11regulation of retinoic acid receptor signaling pathway (GO:0048385)4.30012972
12mitotic sister chromatid segregation (GO:0000070)4.25278886
13metaphase plate congression (GO:0051310)4.24299110
14kinetochore organization (GO:0051383)4.18303254
15protein localization to kinetochore (GO:0034501)4.17744386
16sister chromatid segregation (GO:0000819)4.13633311
17protein localization to chromosome, centromeric region (GO:0071459)4.08794743
18regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.06060932
19cilium movement (GO:0003341)3.97745647
20centriole assembly (GO:0098534)3.91578076
21microtubule polymerization or depolymerization (GO:0031109)3.85371138
22kinetochore assembly (GO:0051382)3.75434940
23regulation of centriole replication (GO:0046599)3.67646243
24motile cilium assembly (GO:0044458)3.63861024
25histone exchange (GO:0043486)3.60419190
26DNA replication-independent nucleosome assembly (GO:0006336)3.58702534
27DNA replication-independent nucleosome organization (GO:0034724)3.58702534
28intraciliary transport (GO:0042073)3.58490979
29establishment of chromosome localization (GO:0051303)3.54457658
30regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.43128886
31epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.42590820
32DNA ligation (GO:0006266)3.41913395
33protein localization to chromosome (GO:0034502)3.30425886
34DNA replication initiation (GO:0006270)3.30300403
35spindle checkpoint (GO:0031577)3.26698937
36DNA strand elongation involved in DNA replication (GO:0006271)3.25774691
37DNA unwinding involved in DNA replication (GO:0006268)3.24005576
38mitotic spindle checkpoint (GO:0071174)3.17042805
39telomere maintenance via semi-conservative replication (GO:0032201)3.15426123
40DNA strand elongation (GO:0022616)3.13555136
41chromosome condensation (GO:0030261)3.13266513
42regulation of chromosome segregation (GO:0051983)3.12008675
43regulation of centrosome cycle (GO:0046605)3.11392877
44negative regulation of DNA-dependent DNA replication (GO:2000104)3.07995279
45regulation of meiosis I (GO:0060631)3.06317627
46meiotic cell cycle (GO:0051321)3.01713583
47DNA replication checkpoint (GO:0000076)3.01541928
48cell proliferation in forebrain (GO:0021846)3.00646184
49negative regulation of chromosome segregation (GO:0051985)3.00320973
50attachment of spindle microtubules to kinetochore (GO:0008608)2.99657474
51positive regulation of gastrulation (GO:2000543)2.98052537
52negative regulation of mitotic sister chromatid segregation (GO:0033048)2.97486484
53negative regulation of mitotic sister chromatid separation (GO:2000816)2.97486484
54negative regulation of sister chromatid segregation (GO:0033046)2.97486484
55negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.97486484
56negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.97486484
57translesion synthesis (GO:0019985)2.91783764
58regulation of mitotic metaphase/anaphase transition (GO:0030071)2.91486250
59regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.91486250
60mitotic sister chromatid cohesion (GO:0007064)2.89900893
61nucleotide-excision repair, DNA gap filling (GO:0006297)2.89367794
62histone H2A acetylation (GO:0043968)2.89117228
63mitotic spindle assembly checkpoint (GO:0007094)2.86771736
64regulation of sister chromatid segregation (GO:0033045)2.86515431
65regulation of mitotic sister chromatid separation (GO:0010965)2.86515431
66regulation of mitotic sister chromatid segregation (GO:0033047)2.86515431
67spindle assembly checkpoint (GO:0071173)2.85765692
68peristalsis (GO:0030432)2.84302676
69mitotic spindle organization (GO:0007052)2.81926572
70mitotic recombination (GO:0006312)2.80946314
71chromosome segregation (GO:0007059)2.80489141
72regulation of spindle organization (GO:0090224)2.79410496
73DNA packaging (GO:0006323)2.75323739
74negative regulation of mitosis (GO:0045839)2.74403921
75chromatin assembly or disassembly (GO:0006333)2.73768823
76positive regulation of chromosome segregation (GO:0051984)2.72955717
77substrate-independent telencephalic tangential migration (GO:0021826)2.71136143
78substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.71136143
79negative regulation of DNA recombination (GO:0045910)2.70917868
80intra-S DNA damage checkpoint (GO:0031573)2.70055685
81regulation of DNA methylation (GO:0044030)2.69299524
82postreplication repair (GO:0006301)2.69219025
83spindle assembly involved in mitosis (GO:0090307)2.67442088
84DNA double-strand break processing (GO:0000729)2.67403107
85centrosome organization (GO:0051297)2.64754854
86spermatid nucleus differentiation (GO:0007289)2.64527528
87cilium organization (GO:0044782)2.64493293
88regulation of double-strand break repair via homologous recombination (GO:0010569)2.62064214
89cilium or flagellum-dependent cell motility (GO:0001539)2.60288877
90ATP-dependent chromatin remodeling (GO:0043044)2.58996385
91regulation of centrosome duplication (GO:0010824)2.58101195
92establishment of integrated proviral latency (GO:0075713)2.57749818
93DNA replication-dependent nucleosome assembly (GO:0006335)2.57742149
94DNA replication-dependent nucleosome organization (GO:0034723)2.57742149
95DNA topological change (GO:0006265)2.57314248
96regulation of mitotic spindle checkpoint (GO:1903504)2.56746540
97regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.56746540
98synapsis (GO:0007129)2.56666597
99cilium assembly (GO:0042384)2.55863570
100positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.55702632

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.32722610
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.09616669
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.89710949
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.34747451
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.40487258
6SALL1_21062744_ChIP-ChIP_HESCs_Human3.26960454
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.17423096
8AR_21909140_ChIP-Seq_LNCAP_Human3.12943249
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.90517221
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.80994979
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.60906005
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.58960002
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.34551062
14KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.24173674
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.23831973
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.19852165
17MYC_18555785_ChIP-Seq_MESCs_Mouse2.07365769
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.06136664
19ELK1_19687146_ChIP-ChIP_HELA_Human2.00771591
20E2F1_21310950_ChIP-Seq_MCF-7_Human1.97729823
21EWS_26573619_Chip-Seq_HEK293_Human1.94487252
22TP63_19390658_ChIP-ChIP_HaCaT_Human1.86276971
23EZH2_22144423_ChIP-Seq_EOC_Human1.83632578
24ZNF274_21170338_ChIP-Seq_K562_Hela1.74660584
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.70822996
26PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69416313
27TAF15_26573619_Chip-Seq_HEK293_Human1.68585262
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.58361265
29SOX2_18555785_ChIP-Seq_MESCs_Mouse1.55452649
30MYC_19030024_ChIP-ChIP_MESCs_Mouse1.54963316
31FUS_26573619_Chip-Seq_HEK293_Human1.54885701
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.54556814
33TTF2_22483619_ChIP-Seq_HELA_Human1.53634442
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.53206704
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51229000
36PADI4_21655091_ChIP-ChIP_MCF-7_Human1.50685443
37YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48942787
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.48590667
39DCP1A_22483619_ChIP-Seq_HELA_Human1.42063823
40MYC_18940864_ChIP-ChIP_HL60_Human1.41714074
41JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.40401578
42MYC_19079543_ChIP-ChIP_MESCs_Mouse1.40100293
43VDR_23849224_ChIP-Seq_CD4+_Human1.37927638
44VDR_22108803_ChIP-Seq_LS180_Human1.37208945
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36840593
46NELFA_20434984_ChIP-Seq_ESCs_Mouse1.34773304
47FOXP3_21729870_ChIP-Seq_TREG_Human1.33538664
48HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.33479885
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.33446825
50POU5F1_16153702_ChIP-ChIP_HESCs_Human1.32452520
51MYC_18358816_ChIP-ChIP_MESCs_Mouse1.32256092
52SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.30113029
53RNF2_27304074_Chip-Seq_NSC_Mouse1.29398706
54CBX2_27304074_Chip-Seq_ESCs_Mouse1.28626004
55XRN2_22483619_ChIP-Seq_HELA_Human1.26415370
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24156284
57GABP_19822575_ChIP-Seq_HepG2_Human1.23433145
58SOX2_16153702_ChIP-ChIP_HESCs_Human1.22447302
59TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17730104
60ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.16645099
61ESR1_15608294_ChIP-ChIP_MCF-7_Human1.16365262
62GATA1_26923725_Chip-Seq_HPCs_Mouse1.12399477
63E2F1_18555785_ChIP-Seq_MESCs_Mouse1.10443077
64HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.10306429
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.08811434
66CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05612283
67POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.05010716
68CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03174050
69THAP11_20581084_ChIP-Seq_MESCs_Mouse1.02842614
70P300_19829295_ChIP-Seq_ESCs_Human1.01140561
71PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00308703
72E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99062571
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98422573
74IGF1R_20145208_ChIP-Seq_DFB_Human0.94667663
75CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94209102
76MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.93962592
77NANOG_16153702_ChIP-ChIP_HESCs_Human0.91214408
78CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.88113053
79POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.87487537
80GBX2_23144817_ChIP-Seq_PC3_Human0.86920785
81KDM5A_27292631_Chip-Seq_BREAST_Human0.86316342
82CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.86066066
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.85031886
84IRF1_19129219_ChIP-ChIP_H3396_Human0.84681053
85GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83769830
86SOX17_20123909_ChIP-Seq_XEN_Mouse0.83561731
87GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.83097267
88NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.82471363
89SOX9_26525672_Chip-Seq_HEART_Mouse0.81444666
90CTBP1_25329375_ChIP-Seq_LNCAP_Human0.80664909
91TOP2B_26459242_ChIP-Seq_MCF-7_Human0.78850677
92YY1_21170310_ChIP-Seq_MESCs_Mouse0.78480142
93SMAD4_21799915_ChIP-Seq_A2780_Human0.78186057
94EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.77381034
95BMI1_23680149_ChIP-Seq_NPCS_Mouse0.76827542
96ZFX_18555785_ChIP-Seq_MESCs_Mouse0.76732132
97EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.76153689
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.75844392
99FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.74980822
100HOXB4_20404135_ChIP-ChIP_EML_Mouse0.74284267

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.79054851
2MP0010094_abnormal_chromosome_stability3.22737678
3MP0002234_abnormal_pharynx_morphology2.96743222
4MP0000566_synostosis2.91263945
5MP0003693_abnormal_embryo_hatching2.87910064
6MP0003136_yellow_coat_color2.80401837
7MP0003718_maternal_effect2.77337356
8MP0006292_abnormal_olfactory_placode2.52328036
9MP0008057_abnormal_DNA_replication2.44316745
10MP0008058_abnormal_DNA_repair2.40229401
11MP0003111_abnormal_nucleus_morphology2.27089761
12MP0005394_taste/olfaction_phenotype2.25732469
13MP0005499_abnormal_olfactory_system2.25732469
14MP0003077_abnormal_cell_cycle2.20798587
15MP0003890_abnormal_embryonic-extraembry2.19816288
16MP0008789_abnormal_olfactory_epithelium2.15602176
17MP0001293_anophthalmia2.10958163
18MP0004957_abnormal_blastocyst_morpholog2.03946551
19MP0000778_abnormal_nervous_system1.87220785
20MP0001529_abnormal_vocalization1.84783214
21MP0008932_abnormal_embryonic_tissue1.81298775
22MP0008877_abnormal_DNA_methylation1.75135668
23MP0009697_abnormal_copulation1.73739291
24MP0002160_abnormal_reproductive_system1.68484333
25MP0002233_abnormal_nose_morphology1.64554375
26MP0003315_abnormal_perineum_morphology1.60376050
27MP0003937_abnormal_limbs/digits/tail_de1.59198949
28MP0008995_early_reproductive_senescence1.58303203
29MP0006072_abnormal_retinal_apoptosis1.56996132
30MP0002210_abnormal_sex_determination1.53028125
31MP0003121_genomic_imprinting1.46837163
32MP0002938_white_spotting1.44823963
33MP0006276_abnormal_autonomic_nervous1.43266157
34MP0010030_abnormal_orbit_morphology1.40878150
35MP0001929_abnormal_gametogenesis1.38668398
36MP0003806_abnormal_nucleotide_metabolis1.30563755
37MP0000049_abnormal_middle_ear1.30163280
38MP0005646_abnormal_pituitary_gland1.25488703
39MP0002102_abnormal_ear_morphology1.24298590
40MP0000537_abnormal_urethra_morphology1.23956394
41MP0000653_abnormal_sex_gland1.23114100
42MP0005187_abnormal_penis_morphology1.22625913
43MP0001145_abnormal_male_reproductive1.22210783
44MP0003122_maternal_imprinting1.18403456
45MP0000631_abnormal_neuroendocrine_gland1.17471947
46MP0003861_abnormal_nervous_system1.17440699
47MP0001286_abnormal_eye_development1.13558926
48MP0003698_abnormal_male_reproductive1.12152423
49MP0002085_abnormal_embryonic_tissue1.11163105
50MP0003938_abnormal_ear_development1.10980900
51MP0002084_abnormal_developmental_patter1.09410448
52MP0003755_abnormal_palate_morphology1.05418941
53MP0003942_abnormal_urinary_system1.04932618
54MP0002697_abnormal_eye_size1.04858762
55MP0002184_abnormal_innervation1.01893993
56MP0005253_abnormal_eye_physiology1.01625559
57MP0003935_abnormal_craniofacial_develop1.00186142
58MP0002751_abnormal_autonomic_nervous0.98046804
59MP0001672_abnormal_embryogenesis/_devel0.97681862
60MP0005380_embryogenesis_phenotype0.97681862
61MP0004133_heterotaxia0.97505467
62MP0001697_abnormal_embryo_size0.95960827
63MP0008007_abnormal_cellular_replicative0.95550018
64MP0003119_abnormal_digestive_system0.94558835
65MP0009250_abnormal_appendicular_skeleto0.94490329
66MP0005391_vision/eye_phenotype0.94206889
67MP0000427_abnormal_hair_cycle0.93848728
68MP0001984_abnormal_olfaction0.92518879
69MP0003567_abnormal_fetal_cardiomyocyte0.90250487
70MP0003786_premature_aging0.88469133
71MP0003123_paternal_imprinting0.88346175
72MP0002161_abnormal_fertility/fecundity0.87987823
73MP0000428_abnormal_craniofacial_morphol0.87754755
74MP0000026_abnormal_inner_ear0.87193796
75MP0005389_reproductive_system_phenotype0.86847235
76MP0000647_abnormal_sebaceous_gland0.86203873
77MP0001119_abnormal_female_reproductive0.85251561
78MP0002653_abnormal_ependyma_morphology0.85205642
79MP0001730_embryonic_growth_arrest0.84808883
80MP0003699_abnormal_female_reproductive0.81640956
81MP0005551_abnormal_eye_electrophysiolog0.81245276
82MP0000955_abnormal_spinal_cord0.80271664
83MP0000350_abnormal_cell_proliferation0.80159355
84MP0001346_abnormal_lacrimal_gland0.79174214
85MP0002092_abnormal_eye_morphology0.78939205
86MP0005395_other_phenotype0.78339302
87MP0000534_abnormal_ureter_morphology0.78225177
88MP0001764_abnormal_homeostasis0.77538183
89MP0002111_abnormal_tail_morphology0.75977456
90MP0009703_decreased_birth_body0.75318726
91MP0001324_abnormal_eye_pigmentation0.74539602
92MP0002282_abnormal_trachea_morphology0.72913713
93MP0000383_abnormal_hair_follicle0.72483410
94MP0002152_abnormal_brain_morphology0.70903647
95MP0002080_prenatal_lethality0.70886588
96MP0002088_abnormal_embryonic_growth/wei0.70755417
97MP0003984_embryonic_growth_retardation0.69063916
98MP0003385_abnormal_body_wall0.68876914
99MP0004197_abnormal_fetal_growth/weight/0.67916262
100MP0002752_abnormal_somatic_nervous0.67901335

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.54748831
2Chromsome breakage (HP:0040012)4.22753154
3Abnormal respiratory motile cilium physiology (HP:0012261)3.63365793
4Abnormal ciliary motility (HP:0012262)3.60912909
5Pancreatic fibrosis (HP:0100732)3.58057742
6True hermaphroditism (HP:0010459)3.52425149
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.50468435
8Pancreatic cysts (HP:0001737)3.46756647
9Molar tooth sign on MRI (HP:0002419)3.34619415
10Abnormality of midbrain morphology (HP:0002418)3.34619415
11Abnormal respiratory motile cilium morphology (HP:0005938)3.25504381
12Abnormal respiratory epithelium morphology (HP:0012253)3.25504381
13Meckel diverticulum (HP:0002245)3.24802520
14Oligodactyly (hands) (HP:0001180)3.22010974
15Aplasia/Hypoplasia of the uvula (HP:0010293)3.18428293
16Aplasia/Hypoplasia of the tongue (HP:0010295)3.18057513
17Abnormality of the ileum (HP:0001549)3.14230225
18Birth length less than 3rd percentile (HP:0003561)3.11975615
19Occipital encephalocele (HP:0002085)3.08009065
20Rhinitis (HP:0012384)3.07953483
21Medial flaring of the eyebrow (HP:0010747)3.05331255
22Tubulointerstitial nephritis (HP:0001970)3.04626801
23Supernumerary spleens (HP:0009799)2.86332454
24Congenital primary aphakia (HP:0007707)2.81745650
25Chronic hepatic failure (HP:0100626)2.80244683
26Cystic liver disease (HP:0006706)2.76848948
27Abnormality of chromosome stability (HP:0003220)2.76090260
28Preaxial hand polydactyly (HP:0001177)2.75971285
29Gait imbalance (HP:0002141)2.75517049
30Volvulus (HP:0002580)2.72538038
31Hypoplastic pelvis (HP:0008839)2.69394893
32Fibular aplasia (HP:0002990)2.64834703
33Abnormality of abdominal situs (HP:0011620)2.63696702
34Abdominal situs inversus (HP:0003363)2.63696702
35Postaxial foot polydactyly (HP:0001830)2.60371827
36Abnormality of the labia minora (HP:0012880)2.59781003
37Nephrogenic diabetes insipidus (HP:0009806)2.56150033
38Patellar aplasia (HP:0006443)2.53790749
39Sclerocornea (HP:0000647)2.50634495
40Postaxial hand polydactyly (HP:0001162)2.49814886
41Duodenal stenosis (HP:0100867)2.48530402
42Small intestinal stenosis (HP:0012848)2.48530402
43Nephronophthisis (HP:0000090)2.43905504
44Dynein arm defect of respiratory motile cilia (HP:0012255)2.43104110
45Absent/shortened dynein arms (HP:0200106)2.43104110
46Anencephaly (HP:0002323)2.40105934
47Abnormality of the preputium (HP:0100587)2.37784280
48Genital tract atresia (HP:0001827)2.29334093
49Aplasia/Hypoplasia of the patella (HP:0006498)2.29040423
50Hyperglycinemia (HP:0002154)2.26898440
51Median cleft lip (HP:0000161)2.26411003
52Concave nail (HP:0001598)2.25367225
53Oligodactyly (HP:0012165)2.24018191
54Sloping forehead (HP:0000340)2.21601970
55Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.21064270
56Poor coordination (HP:0002370)2.20753520
57Vaginal atresia (HP:0000148)2.13160956
58Nephroblastoma (Wilms tumor) (HP:0002667)2.12289021
59Impulsivity (HP:0100710)2.11710031
60Delayed CNS myelination (HP:0002188)2.10001433
61Aganglionic megacolon (HP:0002251)2.06681952
62Absent forearm bone (HP:0003953)2.05684332
63Aplasia involving forearm bones (HP:0009822)2.05684332
64Action tremor (HP:0002345)2.03948475
65Abnormality of the duodenum (HP:0002246)2.02595052
66High anterior hairline (HP:0009890)2.01766882
67Abnormality of the carotid arteries (HP:0005344)2.00227031
68Embryonal renal neoplasm (HP:0011794)1.95569500
69Increased serum pyruvate (HP:0003542)1.94460938
70Narrow forehead (HP:0000341)1.92236235
71Chronic bronchitis (HP:0004469)1.92012518
72Abnormality of the septum pellucidum (HP:0007375)1.91329116
73Abnormality of glycolysis (HP:0004366)1.91312174
74Cortical dysplasia (HP:0002539)1.90918699
75Abnormality of the renal medulla (HP:0100957)1.89475608
76Thyroid-stimulating hormone excess (HP:0002925)1.88873829
77Astigmatism (HP:0000483)1.88774267
78Tubulointerstitial abnormality (HP:0001969)1.87109057
79Oculomotor apraxia (HP:0000657)1.86575535
80Infertility (HP:0000789)1.85909779
81Short tibia (HP:0005736)1.84128621
82Decreased testicular size (HP:0008734)1.82209609
83Pendular nystagmus (HP:0012043)1.80881691
84Tubular atrophy (HP:0000092)1.80765580
85Esophageal atresia (HP:0002032)1.80591471
86Arteriovenous malformation (HP:0100026)1.80192529
87Triphalangeal thumb (HP:0001199)1.79733185
88Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.79540252
89Abnormality of alanine metabolism (HP:0010916)1.79540252
90Hyperalaninemia (HP:0003348)1.79540252
91Oligohydramnios (HP:0001562)1.77105157
92Dandy-Walker malformation (HP:0001305)1.76030410
93Absent septum pellucidum (HP:0001331)1.74561937
94Aplasia/Hypoplasia of the tibia (HP:0005772)1.71785246
95Microglossia (HP:0000171)1.71383353
96Gastrointestinal atresia (HP:0002589)1.71347254
97Abnormal lung lobation (HP:0002101)1.70366002
98Small hand (HP:0200055)1.70181492
99Congenital hepatic fibrosis (HP:0002612)1.69736604
100Increased nuchal translucency (HP:0010880)1.68006391

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK44.33711914
2SRPK13.42731358
3BUB13.42641193
4TTK3.26710009
5CDC73.26495484
6ZAK2.96291136
7PBK2.79850072
8WEE12.71589326
9TNIK2.64338253
10NEK12.47539123
11TRIM282.45975020
12PNCK2.35069850
13TSSK62.19226139
14PLK32.15256987
15BRSK22.11736804
16PLK11.98864690
17CCNB11.98784454
18CDK91.61228699
19VRK21.60566389
20BRSK11.54833224
21NUAK11.53589680
22VRK11.52579421
23BMPR1B1.50593629
24EIF2AK11.49620622
25EPHB21.47319360
26NEK21.47072001
27DYRK31.39397054
28BRD41.39362455
29BCR1.36963065
30MKNK21.36303130
31ATR1.35262010
32MKNK11.33911580
33CHEK21.30283609
34CDK81.22396080
35AURKA1.21591247
36LATS11.19595612
37WNK31.16407744
38AURKB1.16241287
39NTRK21.10780682
40CDK70.99642820
41ERBB30.97359980
42ATM0.90182766
43EIF2AK30.88027112
44TGFBR10.84267944
45CDK190.84114386
46CHEK10.83328649
47STK30.81683099
48PLK20.80869988
49MARK10.77254614
50MAPK130.73451825
51DYRK20.71979047
52MINK10.71671031
53EPHA40.69663136
54CDK10.67184130
55MAP3K40.66812986
56NEK60.65797822
57RPS6KB20.64664508
58MET0.64153515
59TAF10.62120220
60PASK0.61878186
61STK160.61812979
62KSR10.60603233
63CDK20.57199903
64PRKCI0.56223590
65MAP3K100.56013211
66WNK40.53986288
67EIF2AK20.53725964
68STK38L0.52360906
69CSNK1E0.51594326
70MAPK150.51448596
71PKN10.51302517
72CDK180.50739639
73CDK30.47615526
74OXSR10.46932294
75CDK150.46696863
76PTK2B0.45124518
77CAMK1G0.45046538
78UHMK10.44639325
79CDK11A0.43176521
80STK40.42933644
81RPS6KB10.41666705
82CSNK2A10.38463425
83CDK140.37909878
84CSNK2A20.37115153
85MELK0.35360704
86NEK90.35268538
87PRKDC0.34647089
88CSNK1G10.33843155
89PRKCG0.31871271
90PRKD30.30361536
91MUSK0.30228335
92ACVR1B0.28659354
93STK390.27913970
94YES10.27853889
95PRKG10.27643656
96BRAF0.26882226
97TAOK30.26821972
98CSNK1G20.26648541
99SGK4940.26203622
100SGK2230.26203622

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.44004450
2Mismatch repair_Homo sapiens_hsa034303.28817434
3Non-homologous end-joining_Homo sapiens_hsa034503.06263583
4Cell cycle_Homo sapiens_hsa041102.99237992
5Homologous recombination_Homo sapiens_hsa034402.98583343
6Fanconi anemia pathway_Homo sapiens_hsa034602.80361582
7Basal transcription factors_Homo sapiens_hsa030222.70959346
8RNA transport_Homo sapiens_hsa030132.47674611
9Spliceosome_Homo sapiens_hsa030402.37794074
10Nucleotide excision repair_Homo sapiens_hsa034202.25654431
11Base excision repair_Homo sapiens_hsa034102.22932465
12RNA degradation_Homo sapiens_hsa030182.14014217
13mRNA surveillance pathway_Homo sapiens_hsa030152.05230755
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.04871292
15Oocyte meiosis_Homo sapiens_hsa041141.89982374
16One carbon pool by folate_Homo sapiens_hsa006701.84980271
17RNA polymerase_Homo sapiens_hsa030201.78687189
18Huntingtons disease_Homo sapiens_hsa050161.69772683
19Parkinsons disease_Homo sapiens_hsa050121.65882082
20Cysteine and methionine metabolism_Homo sapiens_hsa002701.62256373
21Oxidative phosphorylation_Homo sapiens_hsa001901.55530502
22Protein export_Homo sapiens_hsa030601.55427095
23Proteasome_Homo sapiens_hsa030501.49852679
24Ribosome_Homo sapiens_hsa030101.47888313
25Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.37592954
26Nicotine addiction_Homo sapiens_hsa050331.29711606
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.29464135
28Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.29086168
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.29071564
30Steroid biosynthesis_Homo sapiens_hsa001001.28047853
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.27657532
32Pyruvate metabolism_Homo sapiens_hsa006201.24394795
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.22661846
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.21446236
35Pyrimidine metabolism_Homo sapiens_hsa002401.18355690
36Propanoate metabolism_Homo sapiens_hsa006401.16995498
37Basal cell carcinoma_Homo sapiens_hsa052171.13660234
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.13374952
39Purine metabolism_Homo sapiens_hsa002301.12662111
40Hedgehog signaling pathway_Homo sapiens_hsa043401.10075167
41Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.01734295
42Hippo signaling pathway_Homo sapiens_hsa043900.99995601
43p53 signaling pathway_Homo sapiens_hsa041150.96123374
44Biosynthesis of amino acids_Homo sapiens_hsa012300.94233662
45Folate biosynthesis_Homo sapiens_hsa007900.93980139
46TGF-beta signaling pathway_Homo sapiens_hsa043500.88074962
47Alcoholism_Homo sapiens_hsa050340.84471156
48Selenocompound metabolism_Homo sapiens_hsa004500.80671023
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.78907144
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77618045
51Regulation of autophagy_Homo sapiens_hsa041400.76347182
52Glutathione metabolism_Homo sapiens_hsa004800.75442162
53Alzheimers disease_Homo sapiens_hsa050100.71419795
54Arginine biosynthesis_Homo sapiens_hsa002200.67622769
55Axon guidance_Homo sapiens_hsa043600.65714780
56Carbon metabolism_Homo sapiens_hsa012000.64231476
57Gap junction_Homo sapiens_hsa045400.62606490
58GABAergic synapse_Homo sapiens_hsa047270.60945987
59Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.60078065
60Maturity onset diabetes of the young_Homo sapiens_hsa049500.58662033
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58088414
62Olfactory transduction_Homo sapiens_hsa047400.57979651
63Collecting duct acid secretion_Homo sapiens_hsa049660.57813201
64Morphine addiction_Homo sapiens_hsa050320.56277903
65Metabolic pathways_Homo sapiens_hsa011000.55623087
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.55579754
67Synaptic vesicle cycle_Homo sapiens_hsa047210.55327011
68Cocaine addiction_Homo sapiens_hsa050300.54731323
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.54491065
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54121866
71Wnt signaling pathway_Homo sapiens_hsa043100.52996227
72Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52226279
73Arginine and proline metabolism_Homo sapiens_hsa003300.52006673
74Dopaminergic synapse_Homo sapiens_hsa047280.51937383
75Cardiac muscle contraction_Homo sapiens_hsa042600.50238479
76Lysine degradation_Homo sapiens_hsa003100.49703103
77Phototransduction_Homo sapiens_hsa047440.49659192
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48781172
79Adherens junction_Homo sapiens_hsa045200.47961371
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.44779623
81Retinol metabolism_Homo sapiens_hsa008300.42659659
82Peroxisome_Homo sapiens_hsa041460.40510055
83Tight junction_Homo sapiens_hsa045300.39948626
84Butanoate metabolism_Homo sapiens_hsa006500.37913738
85Glutamatergic synapse_Homo sapiens_hsa047240.37545308
86Taste transduction_Homo sapiens_hsa047420.36357582
87Sulfur relay system_Homo sapiens_hsa041220.34226357
88Systemic lupus erythematosus_Homo sapiens_hsa053220.32367807
89N-Glycan biosynthesis_Homo sapiens_hsa005100.32365351
90Vitamin digestion and absorption_Homo sapiens_hsa049770.29711180
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.29617301
92MicroRNAs in cancer_Homo sapiens_hsa052060.28078072
93Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.26886129
94Viral carcinogenesis_Homo sapiens_hsa052030.26412655
95Fatty acid elongation_Homo sapiens_hsa000620.25593374
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.22857783
97Serotonergic synapse_Homo sapiens_hsa047260.22604430
98Melanogenesis_Homo sapiens_hsa049160.19383367
99Phenylalanine metabolism_Homo sapiens_hsa003600.18760907
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18658104

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