

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.92475781 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.48990621 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.48990621 |
| 4 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.23197435 |
| 5 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.15815344 |
| 6 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.15815344 |
| 7 | DNA replication checkpoint (GO:0000076) | 3.97714524 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 3.91848567 |
| 9 | DNA deamination (GO:0045006) | 3.82793867 |
| 10 | chromatin remodeling at centromere (GO:0031055) | 3.79483482 |
| 11 | viral transcription (GO:0019083) | 3.76979998 |
| 12 | cullin deneddylation (GO:0010388) | 3.75987008 |
| 13 | translational termination (GO:0006415) | 3.69695624 |
| 14 | DNA double-strand break processing (GO:0000729) | 3.68010029 |
| 15 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.67380224 |
| 16 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.64153674 |
| 17 | regulation of gene silencing by miRNA (GO:0060964) | 3.64153674 |
| 18 | regulation of gene silencing by RNA (GO:0060966) | 3.64153674 |
| 19 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.59886777 |
| 20 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.58738334 |
| 21 | CENP-A containing nucleosome assembly (GO:0034080) | 3.53052147 |
| 22 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.51601158 |
| 23 | NADH dehydrogenase complex assembly (GO:0010257) | 3.51601158 |
| 24 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.51601158 |
| 25 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.51559830 |
| 26 | protein complex biogenesis (GO:0070271) | 3.50823884 |
| 27 | respiratory chain complex IV assembly (GO:0008535) | 3.50748104 |
| 28 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.48870291 |
| 29 | protein deneddylation (GO:0000338) | 3.48717734 |
| 30 | ribosomal small subunit biogenesis (GO:0042274) | 3.47727663 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.46008104 |
| 32 | behavioral response to nicotine (GO:0035095) | 3.44290373 |
| 33 | ribosomal small subunit assembly (GO:0000028) | 3.43786319 |
| 34 | pseudouridine synthesis (GO:0001522) | 3.43461609 |
| 35 | replication fork processing (GO:0031297) | 3.42096159 |
| 36 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.37976590 |
| 37 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.37207414 |
| 38 | termination of RNA polymerase III transcription (GO:0006386) | 3.37207414 |
| 39 | cotranslational protein targeting to membrane (GO:0006613) | 3.36395777 |
| 40 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.35071235 |
| 41 | ribosomal large subunit biogenesis (GO:0042273) | 3.32579418 |
| 42 | protein-cofactor linkage (GO:0018065) | 3.29879937 |
| 43 | protein targeting to ER (GO:0045047) | 3.29724632 |
| 44 | histone exchange (GO:0043486) | 3.24749551 |
| 45 | maturation of SSU-rRNA (GO:0030490) | 3.21778018 |
| 46 | translational elongation (GO:0006414) | 3.17013702 |
| 47 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.16817093 |
| 48 | cytochrome complex assembly (GO:0017004) | 3.16676111 |
| 49 | rRNA modification (GO:0000154) | 3.15660964 |
| 50 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.13567786 |
| 51 | proteasome assembly (GO:0043248) | 3.11768753 |
| 52 | protein localization to endoplasmic reticulum (GO:0070972) | 3.08886458 |
| 53 | regulation of mesoderm development (GO:2000380) | 3.08511065 |
| 54 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.07910517 |
| 55 | recombinational repair (GO:0000725) | 3.05717500 |
| 56 | protein neddylation (GO:0045116) | 3.04174816 |
| 57 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.03926488 |
| 58 | double-strand break repair via homologous recombination (GO:0000724) | 3.03024495 |
| 59 | electron transport chain (GO:0022900) | 3.01316853 |
| 60 | translation (GO:0006412) | 3.01199717 |
| 61 | rRNA processing (GO:0006364) | 2.99459451 |
| 62 | respiratory electron transport chain (GO:0022904) | 2.95998956 |
| 63 | maturation of 5.8S rRNA (GO:0000460) | 2.95313627 |
| 64 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.94920495 |
| 65 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.94920495 |
| 66 | rRNA metabolic process (GO:0016072) | 2.94726454 |
| 67 | translational initiation (GO:0006413) | 2.91835056 |
| 68 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.91651153 |
| 69 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.91651153 |
| 70 | isotype switching (GO:0045190) | 2.91651153 |
| 71 | fucose catabolic process (GO:0019317) | 2.88149200 |
| 72 | L-fucose metabolic process (GO:0042354) | 2.88149200 |
| 73 | L-fucose catabolic process (GO:0042355) | 2.88149200 |
| 74 | rRNA methylation (GO:0031167) | 2.84980274 |
| 75 | cellular component biogenesis (GO:0044085) | 2.81235819 |
| 76 | DNA damage response, detection of DNA damage (GO:0042769) | 2.78316844 |
| 77 | kinetochore assembly (GO:0051382) | 2.78253599 |
| 78 | tRNA processing (GO:0008033) | 2.77495430 |
| 79 | mitochondrial RNA metabolic process (GO:0000959) | 2.77314836 |
| 80 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.77085984 |
| 81 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.77085984 |
| 82 | protein K6-linked ubiquitination (GO:0085020) | 2.76910114 |
| 83 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.76884368 |
| 84 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.76667198 |
| 85 | regulation of mitochondrial translation (GO:0070129) | 2.73198314 |
| 86 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.71427440 |
| 87 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.71427440 |
| 88 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.71288806 |
| 89 | histone mRNA metabolic process (GO:0008334) | 2.70467862 |
| 90 | cellular protein complex disassembly (GO:0043624) | 2.69771812 |
| 91 | viral life cycle (GO:0019058) | 2.68487807 |
| 92 | synapsis (GO:0007129) | 2.68297100 |
| 93 | kidney morphogenesis (GO:0060993) | 2.68262890 |
| 94 | telomere maintenance via telomerase (GO:0007004) | 2.68052299 |
| 95 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.66147742 |
| 96 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.65139325 |
| 97 | negative regulation of telomere maintenance (GO:0032205) | 2.62678090 |
| 98 | nucleobase biosynthetic process (GO:0046112) | 2.62586799 |
| 99 | kinetochore organization (GO:0051383) | 2.61158911 |
| 100 | spliceosomal snRNP assembly (GO:0000387) | 2.61122731 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.04620399 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.74879793 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.53902801 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.27703178 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.11386632 |
| 6 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99301466 |
| 7 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.87679786 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.84303984 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.67626354 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.63836709 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.53532466 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.45265659 |
| 13 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.42061739 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.37833401 |
| 15 | EWS_26573619_Chip-Seq_HEK293_Human | 2.31893287 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.31538482 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.26328805 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.23548613 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.21559615 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.20441590 |
| 21 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.14096950 |
| 22 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.10114005 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.02097544 |
| 24 | FUS_26573619_Chip-Seq_HEK293_Human | 1.98992738 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.86742179 |
| 26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.83962312 |
| 27 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.82946255 |
| 28 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.68291793 |
| 29 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68040294 |
| 30 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.66903180 |
| 31 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.65705172 |
| 32 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.65154982 |
| 33 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.62535333 |
| 34 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.61177178 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.52846815 |
| 36 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.50637168 |
| 37 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.49994472 |
| 38 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.48369623 |
| 39 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.45972338 |
| 40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.45380352 |
| 41 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.43792114 |
| 42 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.43466935 |
| 43 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.42803118 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42518926 |
| 45 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.40085553 |
| 46 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.38592790 |
| 47 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.38492351 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.37640812 |
| 49 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.35950169 |
| 50 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34106769 |
| 51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33404883 |
| 52 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.32623171 |
| 53 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.31856872 |
| 54 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.30575094 |
| 55 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.29996960 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.29690985 |
| 57 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.27018027 |
| 58 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.27018027 |
| 59 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.27018027 |
| 60 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.19080904 |
| 61 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18801379 |
| 62 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18801379 |
| 63 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.18547294 |
| 64 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17528698 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.16540597 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.16540597 |
| 67 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.15105179 |
| 68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14592859 |
| 69 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.10681615 |
| 70 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.10093262 |
| 71 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08332245 |
| 72 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07856245 |
| 73 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.07836766 |
| 74 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.05371727 |
| 75 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.04644329 |
| 76 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.04341841 |
| 77 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.03863213 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.03618655 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.03618655 |
| 80 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.03607453 |
| 81 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.01504612 |
| 82 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.00868900 |
| 83 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.00785128 |
| 84 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.99218614 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98917328 |
| 86 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.98822802 |
| 87 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98401510 |
| 88 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.97126474 |
| 89 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.96852651 |
| 90 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.96438008 |
| 91 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.94859158 |
| 92 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94859158 |
| 93 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93273954 |
| 94 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.92335445 |
| 95 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91622965 |
| 96 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.91513712 |
| 97 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.90458806 |
| 98 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90083901 |
| 99 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.89828956 |
| 100 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.89038019 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.15350172 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.33203101 |
| 3 | MP0003693_abnormal_embryo_hatching | 2.75252524 |
| 4 | MP0003718_maternal_effect | 2.59881799 |
| 5 | MP0002102_abnormal_ear_morphology | 2.56131226 |
| 6 | MP0008058_abnormal_DNA_repair | 2.51465959 |
| 7 | MP0003890_abnormal_embryonic-extraembry | 2.48444293 |
| 8 | MP0010094_abnormal_chromosome_stability | 2.27398126 |
| 9 | MP0001293_anophthalmia | 2.25258122 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.21677527 |
| 11 | MP0009379_abnormal_foot_pigmentation | 2.15846496 |
| 12 | MP0002938_white_spotting | 2.09031807 |
| 13 | MP0002254_reproductive_system_inflammat | 2.04150834 |
| 14 | MP0004133_heterotaxia | 2.03585051 |
| 15 | MP0004957_abnormal_blastocyst_morpholog | 2.01782254 |
| 16 | MP0008789_abnormal_olfactory_epithelium | 1.99195376 |
| 17 | MP0002736_abnormal_nociception_after | 1.95597509 |
| 18 | MP0003136_yellow_coat_color | 1.85051120 |
| 19 | MP0003119_abnormal_digestive_system | 1.77541617 |
| 20 | MP0003195_calcinosis | 1.75133869 |
| 21 | MP0010030_abnormal_orbit_morphology | 1.74457127 |
| 22 | MP0008872_abnormal_physiological_respon | 1.73855643 |
| 23 | MP0003567_abnormal_fetal_cardiomyocyte | 1.73466410 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.68494013 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.66253391 |
| 26 | MP0008875_abnormal_xenobiotic_pharmacok | 1.63387585 |
| 27 | MP0003941_abnormal_skin_development | 1.55003010 |
| 28 | MP0003111_abnormal_nucleus_morphology | 1.54651271 |
| 29 | MP0008057_abnormal_DNA_replication | 1.54375091 |
| 30 | MP0003937_abnormal_limbs/digits/tail_de | 1.51599966 |
| 31 | MP0003806_abnormal_nucleotide_metabolis | 1.50305652 |
| 32 | MP0005394_taste/olfaction_phenotype | 1.48421288 |
| 33 | MP0005499_abnormal_olfactory_system | 1.48421288 |
| 34 | MP0002277_abnormal_respiratory_mucosa | 1.43691914 |
| 35 | MP0003646_muscle_fatigue | 1.43495876 |
| 36 | MP0002234_abnormal_pharynx_morphology | 1.40308048 |
| 37 | MP0000631_abnormal_neuroendocrine_gland | 1.40281078 |
| 38 | MP0000049_abnormal_middle_ear | 1.37465493 |
| 39 | MP0003077_abnormal_cell_cycle | 1.36486713 |
| 40 | MP0001485_abnormal_pinna_reflex | 1.36002415 |
| 41 | MP0001986_abnormal_taste_sensitivity | 1.31753715 |
| 42 | MP0003283_abnormal_digestive_organ | 1.31597590 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.30078381 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.29734738 |
| 45 | MP0002638_abnormal_pupillary_reflex | 1.24832698 |
| 46 | MP0008932_abnormal_embryonic_tissue | 1.20962939 |
| 47 | MP0005253_abnormal_eye_physiology | 1.20875227 |
| 48 | MP0002160_abnormal_reproductive_system | 1.20620664 |
| 49 | MP0002876_abnormal_thyroid_physiology | 1.20221100 |
| 50 | MP0009697_abnormal_copulation | 1.19934589 |
| 51 | MP0003786_premature_aging | 1.16964656 |
| 52 | MP0003011_delayed_dark_adaptation | 1.15703945 |
| 53 | MP0001286_abnormal_eye_development | 1.15531051 |
| 54 | MP0005377_hearing/vestibular/ear_phenot | 1.15266312 |
| 55 | MP0003878_abnormal_ear_physiology | 1.15266312 |
| 56 | MP0000516_abnormal_urinary_system | 1.14749794 |
| 57 | MP0005367_renal/urinary_system_phenotyp | 1.14749794 |
| 58 | MP0004147_increased_porphyrin_level | 1.14403826 |
| 59 | MP0002751_abnormal_autonomic_nervous | 1.13159621 |
| 60 | MP0005084_abnormal_gallbladder_morpholo | 1.12522708 |
| 61 | MP0005389_reproductive_system_phenotype | 1.12433793 |
| 62 | MP0003938_abnormal_ear_development | 1.11958624 |
| 63 | MP0000427_abnormal_hair_cycle | 1.11180380 |
| 64 | MP0002233_abnormal_nose_morphology | 1.11025319 |
| 65 | MP0004885_abnormal_endolymph | 1.08334377 |
| 66 | MP0005645_abnormal_hypothalamus_physiol | 1.05612337 |
| 67 | MP0001188_hyperpigmentation | 1.05053052 |
| 68 | MP0003186_abnormal_redox_activity | 1.04179233 |
| 69 | MP0001984_abnormal_olfaction | 1.01648960 |
| 70 | MP0008007_abnormal_cellular_replicative | 0.99973253 |
| 71 | MP0005646_abnormal_pituitary_gland | 0.97187274 |
| 72 | MP0003880_abnormal_central_pattern | 0.97007615 |
| 73 | MP0002210_abnormal_sex_determination | 0.95999869 |
| 74 | MP0001919_abnormal_reproductive_system | 0.94183080 |
| 75 | MP0001929_abnormal_gametogenesis | 0.90915597 |
| 76 | MP0006036_abnormal_mitochondrial_physio | 0.90217616 |
| 77 | MP0005410_abnormal_fertilization | 0.89852821 |
| 78 | MP0004142_abnormal_muscle_tone | 0.89841676 |
| 79 | MP0005075_abnormal_melanosome_morpholog | 0.89823984 |
| 80 | MP0000647_abnormal_sebaceous_gland | 0.87998991 |
| 81 | MP0002163_abnormal_gland_morphology | 0.87724292 |
| 82 | MP0008995_early_reproductive_senescence | 0.87109916 |
| 83 | MP0005195_abnormal_posterior_eye | 0.85395389 |
| 84 | MP0000653_abnormal_sex_gland | 0.83557717 |
| 85 | MP0001529_abnormal_vocalization | 0.80847087 |
| 86 | MP0001119_abnormal_female_reproductive | 0.80690258 |
| 87 | MP0009745_abnormal_behavioral_response | 0.79650078 |
| 88 | MP0001145_abnormal_male_reproductive | 0.79506445 |
| 89 | MP0002653_abnormal_ependyma_morphology | 0.79236239 |
| 90 | MP0004742_abnormal_vestibular_system | 0.76888592 |
| 91 | MP0002272_abnormal_nervous_system | 0.76852326 |
| 92 | MP0001324_abnormal_eye_pigmentation | 0.76726947 |
| 93 | MP0004145_abnormal_muscle_electrophysio | 0.76245322 |
| 94 | MP0003137_abnormal_impulse_conducting | 0.75379283 |
| 95 | MP0005391_vision/eye_phenotype | 0.75112673 |
| 96 | MP0004043_abnormal_pH_regulation | 0.74466531 |
| 97 | MP0002111_abnormal_tail_morphology | 0.73829689 |
| 98 | MP0004215_abnormal_myocardial_fiber | 0.73651161 |
| 99 | MP0003315_abnormal_perineum_morphology | 0.73482013 |
| 100 | MP0009046_muscle_twitch | 0.72092884 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic cysts (HP:0001737) | 3.39156218 |
| 2 | Molar tooth sign on MRI (HP:0002419) | 3.14367948 |
| 3 | Abnormality of midbrain morphology (HP:0002418) | 3.14367948 |
| 4 | Septo-optic dysplasia (HP:0100842) | 2.94259626 |
| 5 | Colon cancer (HP:0003003) | 2.92067852 |
| 6 | Lipid accumulation in hepatocytes (HP:0006561) | 2.90902844 |
| 7 | Abnormal number of erythroid precursors (HP:0012131) | 2.90697340 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 2.89504527 |
| 9 | Abnormality of the labia minora (HP:0012880) | 2.88976169 |
| 10 | Methylmalonic acidemia (HP:0002912) | 2.84156191 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 2.79082143 |
| 12 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.77367196 |
| 13 | Nephronophthisis (HP:0000090) | 2.76061482 |
| 14 | Pancreatic fibrosis (HP:0100732) | 2.71654509 |
| 15 | Mitochondrial inheritance (HP:0001427) | 2.69725351 |
| 16 | Abnormality of alanine metabolism (HP:0010916) | 2.66936195 |
| 17 | Hyperalaninemia (HP:0003348) | 2.66936195 |
| 18 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.66936195 |
| 19 | Acute encephalopathy (HP:0006846) | 2.64066695 |
| 20 | Increased CSF lactate (HP:0002490) | 2.62812309 |
| 21 | True hermaphroditism (HP:0010459) | 2.57926075 |
| 22 | Bilateral microphthalmos (HP:0007633) | 2.55972538 |
| 23 | Meckel diverticulum (HP:0002245) | 2.53702487 |
| 24 | Congenital, generalized hypertrichosis (HP:0004540) | 2.53077417 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 2.50518932 |
| 26 | Abnormality of the ileum (HP:0001549) | 2.49029663 |
| 27 | Macrocytic anemia (HP:0001972) | 2.45511032 |
| 28 | Stenosis of the external auditory canal (HP:0000402) | 2.45418429 |
| 29 | Reticulocytopenia (HP:0001896) | 2.40540496 |
| 30 | Methylmalonic aciduria (HP:0012120) | 2.39089157 |
| 31 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.37342849 |
| 32 | Abnormality of serum amino acid levels (HP:0003112) | 2.34243276 |
| 33 | Hyperglycinemia (HP:0002154) | 2.28058814 |
| 34 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.27331619 |
| 35 | Abnormality of the renal medulla (HP:0100957) | 2.26273158 |
| 36 | Congenital stationary night blindness (HP:0007642) | 2.24429178 |
| 37 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.22610481 |
| 38 | Abnormality of chromosome stability (HP:0003220) | 2.21906374 |
| 39 | Progressive macrocephaly (HP:0004481) | 2.21465489 |
| 40 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.17376618 |
| 41 | Pendular nystagmus (HP:0012043) | 2.16921102 |
| 42 | Hyperglycinuria (HP:0003108) | 2.16637500 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.15226643 |
| 44 | Abnormality of the renal cortex (HP:0011035) | 2.14406236 |
| 45 | Absent thumb (HP:0009777) | 2.11537655 |
| 46 | Abnormality of the pons (HP:0007361) | 2.10975786 |
| 47 | Hepatocellular necrosis (HP:0001404) | 2.08757815 |
| 48 | Anophthalmia (HP:0000528) | 2.08028633 |
| 49 | Birth length less than 3rd percentile (HP:0003561) | 2.05474664 |
| 50 | Triphalangeal thumb (HP:0001199) | 2.05102792 |
| 51 | Renal Fanconi syndrome (HP:0001994) | 2.04744359 |
| 52 | Increased serum lactate (HP:0002151) | 2.03847180 |
| 53 | Chromsome breakage (HP:0040012) | 2.03788888 |
| 54 | Hypoplasia of the pons (HP:0012110) | 2.00280578 |
| 55 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.99093097 |
| 56 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.99093097 |
| 57 | Optic nerve hypoplasia (HP:0000609) | 1.98956793 |
| 58 | IgG deficiency (HP:0004315) | 1.98024901 |
| 59 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.97742504 |
| 60 | Abnormality of glycine metabolism (HP:0010895) | 1.97742504 |
| 61 | Intestinal atresia (HP:0011100) | 1.97510475 |
| 62 | Chronic hepatic failure (HP:0100626) | 1.97275357 |
| 63 | Tubular atrophy (HP:0000092) | 1.96644359 |
| 64 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.95928580 |
| 65 | Medial flaring of the eyebrow (HP:0010747) | 1.94424342 |
| 66 | Abnormality of the preputium (HP:0100587) | 1.93914370 |
| 67 | Horseshoe kidney (HP:0000085) | 1.93388824 |
| 68 | Absent septum pellucidum (HP:0001331) | 1.91022165 |
| 69 | Cleft eyelid (HP:0000625) | 1.88367817 |
| 70 | Oligodactyly (hands) (HP:0001180) | 1.87770117 |
| 71 | Maternal diabetes (HP:0009800) | 1.86817374 |
| 72 | Hepatic necrosis (HP:0002605) | 1.86463845 |
| 73 | Sclerocornea (HP:0000647) | 1.85512106 |
| 74 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.84974559 |
| 75 | Abnormality of methionine metabolism (HP:0010901) | 1.84357714 |
| 76 | Abnormal lung lobation (HP:0002101) | 1.83850629 |
| 77 | Patellar aplasia (HP:0006443) | 1.83784180 |
| 78 | Absent radius (HP:0003974) | 1.83585856 |
| 79 | Exertional dyspnea (HP:0002875) | 1.82789368 |
| 80 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.82472061 |
| 81 | Absent forearm bone (HP:0003953) | 1.82265798 |
| 82 | Aplasia involving forearm bones (HP:0009822) | 1.82265798 |
| 83 | Anencephaly (HP:0002323) | 1.81535338 |
| 84 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.80944452 |
| 85 | Ectopic kidney (HP:0000086) | 1.80821171 |
| 86 | Abnormality of abdominal situs (HP:0011620) | 1.80744915 |
| 87 | Abdominal situs inversus (HP:0003363) | 1.80744915 |
| 88 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.79978451 |
| 89 | Type I transferrin isoform profile (HP:0003642) | 1.79075458 |
| 90 | Supernumerary spleens (HP:0009799) | 1.77045807 |
| 91 | Pallor (HP:0000980) | 1.76679281 |
| 92 | Abnormality of the duodenum (HP:0002246) | 1.76412998 |
| 93 | Abnormality of homocysteine metabolism (HP:0010919) | 1.76259325 |
| 94 | Homocystinuria (HP:0002156) | 1.76259325 |
| 95 | Progressive inability to walk (HP:0002505) | 1.75721883 |
| 96 | Duodenal stenosis (HP:0100867) | 1.75397572 |
| 97 | Small intestinal stenosis (HP:0012848) | 1.75397572 |
| 98 | Clubbing of toes (HP:0100760) | 1.74780844 |
| 99 | Lactic acidosis (HP:0003128) | 1.74698791 |
| 100 | Cerebral edema (HP:0002181) | 1.74588660 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 3.27238357 |
| 2 | TLK1 | 3.25849501 |
| 3 | NUAK1 | 3.20329247 |
| 4 | VRK2 | 2.73040643 |
| 5 | BMPR1B | 2.60321793 |
| 6 | BUB1 | 2.57357213 |
| 7 | WNK3 | 2.51220227 |
| 8 | CDC7 | 2.31490003 |
| 9 | STK16 | 2.30955565 |
| 10 | MKNK2 | 2.25202185 |
| 11 | ADRBK2 | 2.22124354 |
| 12 | GRK1 | 2.14217251 |
| 13 | PLK4 | 2.14087509 |
| 14 | ACVR1B | 2.12839416 |
| 15 | MAP4K2 | 2.10346216 |
| 16 | FRK | 2.07043050 |
| 17 | VRK1 | 2.03062378 |
| 18 | TNIK | 2.01087419 |
| 19 | MST4 | 1.89621237 |
| 20 | SRPK1 | 1.79333581 |
| 21 | PLK3 | 1.71372718 |
| 22 | MKNK1 | 1.71340765 |
| 23 | WNK4 | 1.69209844 |
| 24 | OXSR1 | 1.62711936 |
| 25 | INSRR | 1.49782181 |
| 26 | BRSK2 | 1.49717554 |
| 27 | TTK | 1.49645162 |
| 28 | TSSK6 | 1.46763657 |
| 29 | CDK19 | 1.46524666 |
| 30 | WEE1 | 1.42699023 |
| 31 | TRIM28 | 1.39253726 |
| 32 | PBK | 1.33989926 |
| 33 | NME1 | 1.33068732 |
| 34 | TAF1 | 1.27426864 |
| 35 | STK39 | 1.23639538 |
| 36 | PLK1 | 1.18849712 |
| 37 | DYRK2 | 1.16257897 |
| 38 | TXK | 1.14583962 |
| 39 | PASK | 1.06421658 |
| 40 | EIF2AK3 | 1.06268479 |
| 41 | TGFBR1 | 1.03356934 |
| 42 | MAPK13 | 1.02372819 |
| 43 | PNCK | 1.00606511 |
| 44 | PINK1 | 0.98124701 |
| 45 | STK38L | 0.95939575 |
| 46 | TIE1 | 0.94044393 |
| 47 | TAOK3 | 0.92322437 |
| 48 | ERBB4 | 0.89660473 |
| 49 | BCKDK | 0.89031537 |
| 50 | CHEK2 | 0.86831426 |
| 51 | ATR | 0.86238625 |
| 52 | NEK2 | 0.79829559 |
| 53 | MAP3K4 | 0.78977624 |
| 54 | NEK1 | 0.78591727 |
| 55 | CSNK1G1 | 0.75789583 |
| 56 | AURKB | 0.75651814 |
| 57 | STK3 | 0.75456606 |
| 58 | MAP2K2 | 0.71636867 |
| 59 | EIF2AK2 | 0.68569233 |
| 60 | PRKCG | 0.65452966 |
| 61 | RPS6KA5 | 0.64919357 |
| 62 | TEC | 0.64001698 |
| 63 | PRKCE | 0.63966866 |
| 64 | PDK2 | 0.63346231 |
| 65 | ATM | 0.62401174 |
| 66 | PLK2 | 0.58234597 |
| 67 | CASK | 0.58151084 |
| 68 | CSNK1G2 | 0.57969475 |
| 69 | WNK1 | 0.55839483 |
| 70 | ADRBK1 | 0.55553227 |
| 71 | EIF2AK1 | 0.54858766 |
| 72 | FLT3 | 0.54485312 |
| 73 | CSNK1G3 | 0.53451348 |
| 74 | CSNK2A1 | 0.51478501 |
| 75 | PRKCI | 0.51137676 |
| 76 | RPS6KB2 | 0.48768113 |
| 77 | PAK3 | 0.47309321 |
| 78 | CSNK2A2 | 0.46524111 |
| 79 | CHEK1 | 0.46283670 |
| 80 | PHKG1 | 0.44804575 |
| 81 | PHKG2 | 0.44804575 |
| 82 | CSNK1A1 | 0.43067688 |
| 83 | FGFR2 | 0.43000195 |
| 84 | FGFR1 | 0.42650999 |
| 85 | CSNK1E | 0.41799761 |
| 86 | MAP3K12 | 0.40450823 |
| 87 | PKN1 | 0.38729083 |
| 88 | NLK | 0.38093375 |
| 89 | CDK3 | 0.37899786 |
| 90 | OBSCN | 0.37899439 |
| 91 | DYRK3 | 0.36668384 |
| 92 | CSNK1A1L | 0.36316450 |
| 93 | MAPKAPK5 | 0.36141090 |
| 94 | IKBKB | 0.35515811 |
| 95 | DAPK2 | 0.35113547 |
| 96 | CDK8 | 0.35095743 |
| 97 | BCR | 0.34887670 |
| 98 | CDK1 | 0.34108930 |
| 99 | PIM1 | 0.33513336 |
| 100 | CSNK1D | 0.33063438 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.01453677 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.17063094 |
| 3 | Homologous recombination_Homo sapiens_hsa03440 | 2.83492988 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.70109753 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.64446562 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 2.63824518 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.55906740 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.43818808 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.42386928 |
| 10 | Basal transcription factors_Homo sapiens_hsa03022 | 2.38089524 |
| 11 | DNA replication_Homo sapiens_hsa03030 | 2.19983282 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 1.98522263 |
| 13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.96784629 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.93430680 |
| 15 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.91520256 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.89697408 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.89560146 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.74353437 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.68142369 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.67907230 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.63708422 |
| 22 | RNA transport_Homo sapiens_hsa03013 | 1.59664624 |
| 23 | Alzheimers disease_Homo sapiens_hsa05010 | 1.57516081 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.51340713 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.47973072 |
| 26 | Base excision repair_Homo sapiens_hsa03410 | 1.45797531 |
| 27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.43803584 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.42864944 |
| 29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.35245493 |
| 30 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.33977520 |
| 31 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.33847102 |
| 32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.29064127 |
| 33 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.25504353 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.25495265 |
| 35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.25318071 |
| 36 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.22823044 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.20883118 |
| 38 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.17170938 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15005887 |
| 40 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.11083105 |
| 41 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.09722024 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.08648441 |
| 43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.08189956 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 1.05654410 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.02836519 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02711001 |
| 47 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.99996203 |
| 48 | Asthma_Homo sapiens_hsa05310 | 0.98051934 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.97465808 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.95786544 |
| 51 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.95030632 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.93807443 |
| 53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.91632167 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.90731276 |
| 55 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.89910896 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.88936010 |
| 57 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.84961014 |
| 58 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.81600375 |
| 59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80520920 |
| 60 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.77646563 |
| 61 | Nicotine addiction_Homo sapiens_hsa05033 | 0.77163771 |
| 62 | Cell cycle_Homo sapiens_hsa04110 | 0.75279921 |
| 63 | Peroxisome_Homo sapiens_hsa04146 | 0.74717233 |
| 64 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.74119912 |
| 65 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.73866801 |
| 66 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73101361 |
| 67 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.72026517 |
| 68 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71822574 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71073544 |
| 70 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.67760592 |
| 71 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.67048349 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.66031362 |
| 73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60147616 |
| 74 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58484280 |
| 75 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.56834144 |
| 76 | Olfactory transduction_Homo sapiens_hsa04740 | 0.55188978 |
| 77 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.54795579 |
| 78 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.53934375 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.53921123 |
| 80 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.53109841 |
| 81 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53091827 |
| 82 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.52602958 |
| 83 | Sulfur relay system_Homo sapiens_hsa04122 | 0.51400896 |
| 84 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.51295787 |
| 85 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.51235952 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.50894530 |
| 87 | Allograft rejection_Homo sapiens_hsa05330 | 0.50047047 |
| 88 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.46316827 |
| 89 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.43565839 |
| 90 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.43350221 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36445952 |
| 92 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.34888541 |
| 93 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.33230816 |
| 94 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32102643 |
| 95 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31844128 |
| 96 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.31708635 |
| 97 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.31425659 |
| 98 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.30403914 |
| 99 | Mineral absorption_Homo sapiens_hsa04978 | 0.28826987 |
| 100 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27408954 |

