ZSCAN10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by miRNA (GO:0060964)5.95655347
2regulation of gene silencing by RNA (GO:0060966)5.95655347
3regulation of posttranscriptional gene silencing (GO:0060147)5.95655347
4L-serine metabolic process (GO:0006563)5.89356247
5regulation of cell fate specification (GO:0042659)5.07364676
6L-alpha-amino acid transmembrane transport (GO:1902475)4.78601923
7formation of translation preinitiation complex (GO:0001731)4.62138544
8DNA unwinding involved in DNA replication (GO:0006268)4.59450805
9establishment of viral latency (GO:0019043)4.58516249
10cell fate commitment involved in formation of primary germ layer (GO:0060795)4.55800673
11DNA replication initiation (GO:0006270)4.49597676
12regulation of Wnt signaling pathway involved in heart development (GO:0003307)4.48823005
13mitotic metaphase plate congression (GO:0007080)4.35195720
14folic acid-containing compound biosynthetic process (GO:0009396)4.32660222
15regulation of chromatin silencing (GO:0031935)4.28643711
16nuclear pore organization (GO:0006999)4.28582521
17nucleobase biosynthetic process (GO:0046112)4.28399451
18DNA replication-dependent nucleosome organization (GO:0034723)4.22638767
19DNA replication-dependent nucleosome assembly (GO:0006335)4.22638767
20somatic diversification of immune receptors via somatic mutation (GO:0002566)4.19322459
21somatic hypermutation of immunoglobulin genes (GO:0016446)4.19322459
22ribosome biogenesis (GO:0042254)4.19026160
23IMP biosynthetic process (GO:0006188)4.18587293
24DNA strand elongation involved in DNA replication (GO:0006271)4.11090998
25protein localization to kinetochore (GO:0034501)4.10707574
26lung-associated mesenchyme development (GO:0060484)4.09114810
27regulation of helicase activity (GO:0051095)4.06751162
28regulation of SMAD protein import into nucleus (GO:0060390)4.02269499
29mitotic nuclear envelope disassembly (GO:0007077)3.95490162
30nuclear pore complex assembly (GO:0051292)3.92153950
31ribosome assembly (GO:0042255)3.90983663
32maturation of SSU-rRNA (GO:0030490)3.90903603
33DNA replication checkpoint (GO:0000076)3.88749610
34purine nucleobase biosynthetic process (GO:0009113)3.88745354
35DNA strand elongation (GO:0022616)3.88537547
36pre-miRNA processing (GO:0031054)3.79387581
37regulation of nuclear cell cycle DNA replication (GO:0033262)3.78657730
38ribonucleoprotein complex biogenesis (GO:0022613)3.73092041
39mitotic sister chromatid segregation (GO:0000070)3.69691228
40negative regulation of translation, ncRNA-mediated (GO:0040033)3.69036580
41regulation of translation, ncRNA-mediated (GO:0045974)3.69036580
42negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.69036580
43positive regulation of catenin import into nucleus (GO:0035413)3.68993607
44histone H4-K12 acetylation (GO:0043983)3.67830074
45membrane disassembly (GO:0030397)3.66844713
46nuclear envelope disassembly (GO:0051081)3.66844713
47cellular protein complex localization (GO:0034629)3.65146785
48metaphase plate congression (GO:0051310)3.64983794
49heterochromatin organization (GO:0070828)3.64258610
50IMP metabolic process (GO:0046040)3.60067613
51histone arginine methylation (GO:0034969)3.59577294
52telomere maintenance via semi-conservative replication (GO:0032201)3.59298474
53paraxial mesoderm development (GO:0048339)3.57591601
54DNA geometric change (GO:0032392)3.56302289
55DNA duplex unwinding (GO:0032508)3.56230211
56establishment of integrated proviral latency (GO:0075713)3.53568607
57serine family amino acid biosynthetic process (GO:0009070)3.53540757
58regulation of cell fate commitment (GO:0010453)3.52935873
59convergent extension (GO:0060026)3.51424358
60protein localization to chromosome, centromeric region (GO:0071459)3.48794803
61negative regulation of telomerase activity (GO:0051974)3.44547572
62nodal signaling pathway (GO:0038092)3.43746197
63negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.39885601
64regulation of histone H3-K9 methylation (GO:0051570)3.39748303
65negative regulation of histone methylation (GO:0031061)3.39730115
66regulation of gene silencing (GO:0060968)3.38638492
67DNA deamination (GO:0045006)3.37376305
68ribosomal large subunit biogenesis (GO:0042273)3.32714416
69nucleosome disassembly (GO:0006337)3.32542028
70protein-DNA complex disassembly (GO:0032986)3.32542028
71anterior/posterior axis specification, embryo (GO:0008595)3.31494338
72regulation of stem cell maintenance (GO:2000036)3.29993198
73rRNA processing (GO:0006364)3.29719193
74spliceosomal snRNP assembly (GO:0000387)3.28846019
75positive regulation of SMAD protein import into nucleus (GO:0060391)3.26356338
76regulation of telomere maintenance via telomerase (GO:0032210)3.23487803
77lysine metabolic process (GO:0006553)3.23392934
78lysine catabolic process (GO:0006554)3.23392934
79chromatin assembly (GO:0031497)3.23198942
80pseudouridine synthesis (GO:0001522)3.22302056
81peptidyl-arginine omega-N-methylation (GO:0035247)3.22166853
82regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.22059184
83ribosomal small subunit biogenesis (GO:0042274)3.21373294
84regulation of translational fidelity (GO:0006450)3.20691015
85protein complex localization (GO:0031503)3.19780484
86rRNA metabolic process (GO:0016072)3.19014500
87regulation of spindle organization (GO:0090224)3.16975399
88negative regulation of gene silencing (GO:0060969)3.16590568
89kinetochore assembly (GO:0051382)3.16540480
90negative regulation of androgen receptor signaling pathway (GO:0060766)3.15630080
91sister chromatid segregation (GO:0000819)3.14422489
92telomere maintenance via telomere lengthening (GO:0010833)3.13450464
93establishment of chromosome localization (GO:0051303)3.12309588
94chromatin remodeling at centromere (GO:0031055)3.11487361
95kinetochore organization (GO:0051383)3.11448690
96peptidyl-arginine N-methylation (GO:0035246)3.10913415
97peptidyl-arginine methylation (GO:0018216)3.10913415
98notochord development (GO:0030903)3.10558548
99determination of adult lifespan (GO:0008340)3.10229652
100rRNA modification (GO:0000154)3.09421023
101single strand break repair (GO:0000012)3.08968100
102ATP-dependent chromatin remodeling (GO:0043044)3.08932068
103positive regulation of chromosome segregation (GO:0051984)3.08085491
104maturation of 5.8S rRNA (GO:0000460)3.07699498
105negative regulation of mitotic sister chromatid separation (GO:2000816)3.07610065
106negative regulation of sister chromatid segregation (GO:0033046)3.07610065
107negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.07610065
108negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.07610065
109negative regulation of mitotic sister chromatid segregation (GO:0033048)3.07610065
110negative regulation of mRNA processing (GO:0050686)3.06884652
111telomere maintenance via recombination (GO:0000722)3.06123717
112regulation of mitotic spindle checkpoint (GO:1903504)3.04626990
113regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.04626990
114translational initiation (GO:0006413)3.03744295
115protein K6-linked ubiquitination (GO:0085020)3.03434357
116histone exchange (GO:0043486)3.01853160
117viral transcription (GO:0019083)3.01584411
118negative regulation of cell fate specification (GO:0009996)3.01138198
119regulation of mitotic spindle organization (GO:0060236)3.00946706
120maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.00652445
121translational termination (GO:0006415)2.98846053
122negative regulation of mRNA metabolic process (GO:1903312)2.98185370
123mitotic recombination (GO:0006312)2.96493828
124CENP-A containing nucleosome assembly (GO:0034080)2.94883337
125negative regulation of cell fate commitment (GO:0010454)2.94022778
126regulation of centrosome cycle (GO:0046605)2.93684970
127establishment of apical/basal cell polarity (GO:0035089)2.92052559
128mismatch repair (GO:0006298)2.91718185
129positive regulation of cell cycle G2/M phase transition (GO:1902751)2.90812140
130positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.90812140
131negative regulation of RNA splicing (GO:0033119)2.90706492
132pore complex assembly (GO:0046931)2.90663285
133nucleotide-excision repair, DNA gap filling (GO:0006297)2.89796358
134mitochondrial DNA metabolic process (GO:0032042)2.89293417
135negative regulation of chromosome segregation (GO:0051985)2.89245497
136DNA replication-independent nucleosome organization (GO:0034724)2.86749782
137DNA replication-independent nucleosome assembly (GO:0006336)2.86749782
138DNA damage response, detection of DNA damage (GO:0042769)2.86471871
139regulation of double-strand break repair via homologous recombination (GO:0010569)2.86402578
140ribosomal small subunit assembly (GO:0000028)2.86381592
141regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.85378750
142folic acid metabolic process (GO:0046655)2.82973174
143regulation of hippo signaling (GO:0035330)2.82440854
144regulation of chromosome segregation (GO:0051983)2.81776994
145translational elongation (GO:0006414)2.81708311
146glycine metabolic process (GO:0006544)2.81335290
147histone H4-K8 acetylation (GO:0043982)2.81298585
148histone H4-K5 acetylation (GO:0043981)2.81298585
149ncRNA catabolic process (GO:0034661)2.80515682

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.54978266
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.25084832
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.49999324
4MYC_19079543_ChIP-ChIP_MESCs_Mouse3.37842765
5KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.30038482
6KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.30038482
7KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.30038482
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.10067592
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.95196414
10SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.89716118
11POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.88041467
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.85139100
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.68176793
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.68111871
15NANOG_18555785_ChIP-Seq_MESCs_Mouse2.47532402
16NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.40338025
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.37797287
18SOX2_16153702_ChIP-ChIP_HESCs_Human2.36526823
19NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.36466061
20ETS1_20019798_ChIP-Seq_JURKAT_Human2.27404499
21KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.24791022
22* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.24311320
23TCF3_18692474_ChIP-Seq_MEFs_Mouse2.24040240
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.18175813
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.18133630
26POU5F1_16153702_ChIP-ChIP_HESCs_Human2.17802803
27* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.12231662
28POU5F1_18358816_ChIP-ChIP_MESCs_Mouse2.11270975
29E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.10177426
30XRN2_22483619_ChIP-Seq_HELA_Human2.07785736
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.06711227
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.03727343
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.95844099
34E2F1_18555785_ChIP-Seq_MESCs_Mouse1.95267661
35CREB1_15753290_ChIP-ChIP_HEK293T_Human1.94701640
36ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.93709187
37TCF3_18692474_ChIP-Seq_MESCs_Mouse1.93177312
38STAT3_1855785_ChIP-Seq_MESCs_Mouse1.92692779
39GABP_17652178_ChIP-ChIP_JURKAT_Human1.91336651
40ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.91305466
41KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.87049253
42SOX2_18555785_ChIP-Seq_MESCs_Mouse1.86450134
43MYCN_18555785_ChIP-Seq_MESCs_Mouse1.83516792
44SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.83382185
45* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.76235486
46NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.69453250
47NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.65548471
48AR_21909140_ChIP-Seq_LNCAP_Human1.63553554
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.63438003
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63295508
51KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.59943120
52HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.58848118
53VDR_23849224_ChIP-Seq_CD4+_Human1.56106037
54EGR1_19374776_ChIP-ChIP_THP-1_Human1.56067158
55TTF2_22483619_ChIP-Seq_HELA_Human1.54309608
56E2F1_21310950_ChIP-Seq_MCF-7_Human1.54301497
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.52937392
58ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52664976
59NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.52636758
60RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.50929155
61SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.50487777
62NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.49121862
63SOX2_18692474_ChIP-Seq_MEFs_Mouse1.47951482
64DCP1A_22483619_ChIP-Seq_HELA_Human1.43566368
65GABP_19822575_ChIP-Seq_HepG2_Human1.43006233
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.42362903
67FOXP3_21729870_ChIP-Seq_TREG_Human1.41281338
68POU5F1_16518401_ChIP-PET_MESCs_Mouse1.40177860
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.36392867
70OCT4_18692474_ChIP-Seq_MEFs_Mouse1.36317734
71GATA1_26923725_Chip-Seq_HPCs_Mouse1.33971772
72* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.33815303
73* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.32240489
74KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31921345
75DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.31780336
76TP63_19390658_ChIP-ChIP_HaCaT_Human1.31484318
77NANOG_18692474_ChIP-Seq_MEFs_Mouse1.30593509
78ESR1_15608294_ChIP-ChIP_MCF-7_Human1.28125716
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27244605
80NANOG_21062744_ChIP-ChIP_HESCs_Human1.27118248
81MYC_22102868_ChIP-Seq_BL_Human1.24636390
82KDM5A_27292631_Chip-Seq_BREAST_Human1.24307696
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21846926
84* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.21450151
85HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.21438623
86CIITA_25753668_ChIP-Seq_RAJI_Human1.17434104
87* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.16060874
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14912519
89CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13496187
90MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.12991438
91DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07380917
92MYC_18940864_ChIP-ChIP_HL60_Human1.07039893
93* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06835050
94TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.05669265
95TFEB_21752829_ChIP-Seq_HELA_Human1.03348843
96RBPJ_22232070_ChIP-Seq_NCS_Mouse1.02429123
97HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.02216072
98* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.00995960
99KAP1_27257070_Chip-Seq_ESCs_Mouse1.00886010
100ELK1_19687146_ChIP-ChIP_HELA_Human0.98811702
101IRF1_19129219_ChIP-ChIP_H3396_Human0.98525125
102TBX3_20139965_ChIP-Seq_ESCs_Mouse0.96734761
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96542167
104TBX3_20139965_ChIP-Seq_MESCs_Mouse0.95278560
105CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94484862
106SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94471859
107TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.93919183
108ELF1_17652178_ChIP-ChIP_JURKAT_Human0.92314236
109ERG_21242973_ChIP-ChIP_JURKAT_Human0.92166058
110SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91790400
111* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.88234381
112BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.87540401
113NANOG_16518401_ChIP-PET_MESCs_Mouse0.86158623
114* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.85946708
115NANOG_16153702_ChIP-ChIP_HESCs_Human0.84891013
116PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.82156535
117ZFP281_18757296_ChIP-ChIP_E14_Mouse0.82106409

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.59750312
2MP0004957_abnormal_blastocyst_morpholog4.46241286
3MP0008057_abnormal_DNA_replication4.10074238
4MP0003111_abnormal_nucleus_morphology4.08501412
5MP0010094_abnormal_chromosome_stability3.98063874
6MP0003077_abnormal_cell_cycle3.60938226
7MP0004133_heterotaxia3.46828191
8MP0008058_abnormal_DNA_repair2.95811476
9MP0003806_abnormal_nucleotide_metabolis2.81729404
10MP0003890_abnormal_embryonic-extraembry2.81217838
11MP0002653_abnormal_ependyma_morphology2.75178789
12MP0010352_gastrointestinal_tract_polyps2.66021604
13MP0001730_embryonic_growth_arrest2.61571477
14MP0008932_abnormal_embryonic_tissue2.54943327
15MP0003123_paternal_imprinting2.45226284
16MP0000350_abnormal_cell_proliferation2.39292792
17MP0003119_abnormal_digestive_system2.23369259
18MP0008007_abnormal_cellular_replicative2.19574075
19MP0001672_abnormal_embryogenesis/_devel2.18168125
20MP0005380_embryogenesis_phenotype2.18168125
21MP0010030_abnormal_orbit_morphology2.18086897
22MP0008877_abnormal_DNA_methylation2.15528298
23MP0002084_abnormal_developmental_patter2.06592213
24MP0002085_abnormal_embryonic_tissue2.06074526
25MP0006292_abnormal_olfactory_placode2.03387308
26MP0001293_anophthalmia2.00718315
27MP0001697_abnormal_embryo_size1.98257738
28MP0003283_abnormal_digestive_organ1.94402850
29MP0003984_embryonic_growth_retardation1.85451564
30MP0003718_maternal_effect1.82987370
31MP0002088_abnormal_embryonic_growth/wei1.82479325
32MP0004197_abnormal_fetal_growth/weight/1.76933962
33MP0002086_abnormal_extraembryonic_tissu1.76257972
34MP0003941_abnormal_skin_development1.72363751
35MP0002080_prenatal_lethality1.68417174
36MP0003786_premature_aging1.67444085
37MP0010307_abnormal_tumor_latency1.58198835
38MP0003787_abnormal_imprinting1.58197917
39MP0005377_hearing/vestibular/ear_phenot1.57746004
40MP0003878_abnormal_ear_physiology1.57746004
41MP0000566_synostosis1.49724323
42MP0005076_abnormal_cell_differentiation1.34817207
43MP0003136_yellow_coat_color1.33610701
44MP0001299_abnormal_eye_distance/1.31265380
45MP0000313_abnormal_cell_death1.28577398
46MP0003121_genomic_imprinting1.27737828
47MP0003567_abnormal_fetal_cardiomyocyte1.26973047
48MP0002111_abnormal_tail_morphology1.21692400
49MP0001849_ear_inflammation1.19821879
50MP0000579_abnormal_nail_morphology1.17763209
51MP0001188_hyperpigmentation1.17454774
52MP0004264_abnormal_extraembryonic_tissu1.12796171
53MP0003315_abnormal_perineum_morphology1.11807459
54MP0002210_abnormal_sex_determination1.11795508
55MP0009278_abnormal_bone_marrow1.11201092
56MP0000490_abnormal_crypts_of1.10833086
57MP0004272_abnormal_basement_membrane1.10490869
58MP0001145_abnormal_male_reproductive1.09399281
59MP0000516_abnormal_urinary_system1.07650917
60MP0005367_renal/urinary_system_phenotyp1.07650917
61MP0002019_abnormal_tumor_incidence1.06249167
62MP0000537_abnormal_urethra_morphology1.06247925
63MP0005266_abnormal_metabolism1.06091527
64MP0003122_maternal_imprinting1.02599786
65MP0001286_abnormal_eye_development1.01588998
66MP0009053_abnormal_anal_canal0.99365304
67MP0003705_abnormal_hypodermis_morpholog0.97995683
68MP0000432_abnormal_head_morphology0.94397999
69MP0002160_abnormal_reproductive_system0.93913794
70MP0002938_white_spotting0.93207894
71MP0002089_abnormal_postnatal_growth/wei0.92830583
72MP0009703_decreased_birth_body0.92496970
73MP0003861_abnormal_nervous_system0.91398635
74MP0003566_abnormal_cell_adhesion0.90508512
75MP0002697_abnormal_eye_size0.90117552
76MP0002163_abnormal_gland_morphology0.89154281
77MP0003937_abnormal_limbs/digits/tail_de0.88906169
78MP0002233_abnormal_nose_morphology0.88513043
79MP0001661_extended_life_span0.88508566
80MP0002092_abnormal_eye_morphology0.88065506
81MP0009672_abnormal_birth_weight0.85067052
82MP0000653_abnormal_sex_gland0.84666956
83MP0004185_abnormal_adipocyte_glucose0.82442810
84MP0005501_abnormal_skin_physiology0.82375493
85MP0004858_abnormal_nervous_system0.81680609
86MP0001929_abnormal_gametogenesis0.81330657
87MP0002249_abnormal_larynx_morphology0.80445757
88MP0002751_abnormal_autonomic_nervous0.79033159
89MP0002127_abnormal_cardiovascular_syste0.78354914
90MP0003936_abnormal_reproductive_system0.78346296
91MP0002736_abnormal_nociception_after0.78043167
92MP0000358_abnormal_cell_content/0.77881346
93MP0003186_abnormal_redox_activity0.77209830
94MP0001485_abnormal_pinna_reflex0.77111883
95MP0005023_abnormal_wound_healing0.75447870
96MP0002090_abnormal_vision0.73535724
97MP0005384_cellular_phenotype0.72614847
98MP0003115_abnormal_respiratory_system0.72509146
99MP0001177_atelectasis0.72408908
100MP0000428_abnormal_craniofacial_morphol0.71443121
101MP0005394_taste/olfaction_phenotype0.71244405
102MP0005499_abnormal_olfactory_system0.71244405
103MP0002332_abnormal_exercise_endurance0.70499564
104MP0003935_abnormal_craniofacial_develop0.70332347
105MP0000049_abnormal_middle_ear0.68682612
106MP0005389_reproductive_system_phenotype0.67708091
107MP0003938_abnormal_ear_development0.67650829
108MP0003755_abnormal_palate_morphology0.67043295
109MP0008770_decreased_survivor_rate0.66532479
110MP0002254_reproductive_system_inflammat0.66510053
111MP0002081_perinatal_lethality0.66102425
112MP0005621_abnormal_cell_physiology0.65974915
113MP0003942_abnormal_urinary_system0.65365413
114MP0009697_abnormal_copulation0.64903109
115MP0001915_intracranial_hemorrhage0.64480042
116MP0002925_abnormal_cardiovascular_devel0.64396052
117MP0002269_muscular_atrophy0.64038063
118MP0000750_abnormal_muscle_regeneration0.63587377
119MP0004233_abnormal_muscle_weight0.62922757
120MP0002796_impaired_skin_barrier0.62886958
121MP0008789_abnormal_olfactory_epithelium0.61616203
122MP0006035_abnormal_mitochondrial_morpho0.61143502
123MP0000678_abnormal_parathyroid_gland0.61123905
124MP0002114_abnormal_axial_skeleton0.60453837
125MP0000762_abnormal_tongue_morphology0.59956188
126MP0006072_abnormal_retinal_apoptosis0.59817585
127MP0002277_abnormal_respiratory_mucosa0.57989011
128MP0001984_abnormal_olfaction0.57718501
129MP0010630_abnormal_cardiac_muscle0.53460685
130MP0001346_abnormal_lacrimal_gland0.52492924
131MP0002116_abnormal_craniofacial_bone0.51664399

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)5.09192427
2Birth length less than 3rd percentile (HP:0003561)4.37646670
3Hepatoblastoma (HP:0002884)4.29021287
4Breast hypoplasia (HP:0003187)4.21729649
5Supernumerary spleens (HP:0009799)4.11075473
6Abnormality of the labia minora (HP:0012880)3.90558965
7Absent radius (HP:0003974)3.81485559
8Spastic diplegia (HP:0001264)3.75864460
9Rib fusion (HP:0000902)3.75755190
10Choanal stenosis (HP:0000452)3.74105479
11Medulloblastoma (HP:0002885)3.72231401
12Colon cancer (HP:0003003)3.58866924
13Aplasia involving forearm bones (HP:0009822)3.58636673
14Absent forearm bone (HP:0003953)3.58636673
15Selective tooth agenesis (HP:0001592)3.56932064
16Astrocytoma (HP:0009592)3.54396421
17Abnormality of the astrocytes (HP:0100707)3.54396421
18Aplasia/hypoplasia of the humerus (HP:0006507)3.48235549
19Abnormality of abdominal situs (HP:0011620)3.44308123
20Abdominal situs inversus (HP:0003363)3.44308123
21Bilateral microphthalmos (HP:0007633)3.35425097
22Chromosomal breakage induced by crosslinking agents (HP:0003221)3.31868538
23Nephroblastoma (Wilms tumor) (HP:0002667)3.30113070
24Rhabdomyosarcoma (HP:0002859)3.27428492
25Agnosia (HP:0010524)3.25096472
26Neoplasm of the oral cavity (HP:0100649)3.21117216
27Short humerus (HP:0005792)3.20699616
28Chromsome breakage (HP:0040012)3.19429399
29Carpal bone hypoplasia (HP:0001498)3.17938420
30Rectal fistula (HP:0100590)3.16664134
31Rectovaginal fistula (HP:0000143)3.16664134
32Patellar aplasia (HP:0006443)3.13952803
33Cortical dysplasia (HP:0002539)3.13729745
34Chronic bronchitis (HP:0004469)3.07819587
35Embryonal renal neoplasm (HP:0011794)3.07788653
36Absent thumb (HP:0009777)3.01879927
37Glioma (HP:0009733)2.96059580
38Impulsivity (HP:0100710)2.95381773
39Reticulocytopenia (HP:0001896)2.92898129
40Oral leukoplakia (HP:0002745)2.90952092
41Aplasia/Hypoplasia of the patella (HP:0006498)2.87586883
42Hyperglycinuria (HP:0003108)2.86556915
43Neoplasm of striated muscle (HP:0009728)2.84779309
44Neoplasm of the adrenal cortex (HP:0100641)2.84045766
45Maternal diabetes (HP:0009800)2.82863442
46Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.79130597
47Abnormal number of incisors (HP:0011064)2.78629369
48Degeneration of anterior horn cells (HP:0002398)2.78098997
49Abnormality of the anterior horn cell (HP:0006802)2.78098997
50Intestinal fistula (HP:0100819)2.76698090
51Asplenia (HP:0001746)2.71142559
52Hyperglycinemia (HP:0002154)2.69393945
53Missing ribs (HP:0000921)2.68060134
54Trismus (HP:0000211)2.67456915
55Cerebral hypomyelination (HP:0006808)2.66774208
56Shawl scrotum (HP:0000049)2.63757626
57Vaginal fistula (HP:0004320)2.63601133
58Turricephaly (HP:0000262)2.59562322
59Meckel diverticulum (HP:0002245)2.58652068
60Abnormality of the ileum (HP:0001549)2.58141849
61Short hallux (HP:0010109)2.55456893
62Esophageal atresia (HP:0002032)2.54036859
63Abnormality of homocysteine metabolism (HP:0010919)2.49802434
64Homocystinuria (HP:0002156)2.49802434
65Rough bone trabeculation (HP:0100670)2.49768889
66Aplasia/Hypoplasia of the spleen (HP:0010451)2.48892021
67Skull defect (HP:0001362)2.48358210
68Abnormality of serine family amino acid metabolism (HP:0010894)2.47591306
69Abnormality of glycine metabolism (HP:0010895)2.47591306
70Bronchomalacia (HP:0002780)2.47016391
71Abnormality of the salivary glands (HP:0010286)2.46069258
72Aplasia/Hypoplasia of the uvula (HP:0010293)2.44088316
73Aplasia/Hypoplasia of the hallux (HP:0008362)2.42783812
74Multiple enchondromatosis (HP:0005701)2.38157601
75Stenosis of the external auditory canal (HP:0000402)2.36991622
76Basal cell carcinoma (HP:0002671)2.36897916
77Hypoglycemic seizures (HP:0002173)2.36314196
78Abnormality of the septum pellucidum (HP:0007375)2.34970332
79Increased nuchal translucency (HP:0010880)2.34853042
80Abnormality of the preputium (HP:0100587)2.34592179
81Absent septum pellucidum (HP:0001331)2.34198819
82Synostosis involving the elbow (HP:0003938)2.33894574
83Humeroradial synostosis (HP:0003041)2.33894574
84Fused cervical vertebrae (HP:0002949)2.32839135
85Partial duplication of thumb phalanx (HP:0009944)2.32665789
86Gastrointestinal carcinoma (HP:0002672)2.32331733
87Malignant gastrointestinal tract tumors (HP:0006749)2.32331733
88Abnormality of pyrimidine metabolism (HP:0004353)2.30749742
89Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28925562
90Tracheoesophageal fistula (HP:0002575)2.28467972
91Aqueductal stenosis (HP:0002410)2.27604281
92Facial cleft (HP:0002006)2.26339643
93Abnormality of the lower motor neuron (HP:0002366)2.25969560
94Vertebral fusion (HP:0002948)2.24938525
95Bifid tongue (HP:0010297)2.24935375
96Myelomeningocele (HP:0002475)2.24356000
97Premature ovarian failure (HP:0008209)2.24113099
98Neoplasm of the pancreas (HP:0002894)2.22550084
99Biliary tract neoplasm (HP:0100574)2.20539338
100Breast aplasia (HP:0100783)2.19088271
101Horseshoe kidney (HP:0000085)2.17199604
102Intestinal atresia (HP:0011100)2.16108227
103Abnormality of chromosome stability (HP:0003220)2.15740597
104Supernumerary bones of the axial skeleton (HP:0009144)2.14180775
105Anal stenosis (HP:0002025)2.13816993
106Broad thumb (HP:0011304)2.08236282
107Gastrointestinal atresia (HP:0002589)2.08197293
108Shallow orbits (HP:0000586)2.07953551
109Generalized hypotonia (HP:0001290)2.07700313
110Premature graying of hair (HP:0002216)2.07652940
111Hemivertebrae (HP:0002937)2.04980333
112High anterior hairline (HP:0009890)2.04724035
113Spinal muscular atrophy (HP:0007269)2.04356570
114Broad metatarsal (HP:0001783)2.03793112
115Aplasia/Hypoplasia of the sternum (HP:0006714)2.03171318
116Atresia of the external auditory canal (HP:0000413)2.03024936
117Cutaneous syndactyly (HP:0012725)2.02351691
118Supernumerary ribs (HP:0005815)2.02304883
119Duplication of thumb phalanx (HP:0009942)2.01686026
120Aplasia/Hypoplasia of the breasts (HP:0010311)2.01266934
121Duplicated collecting system (HP:0000081)2.01108955
122Septo-optic dysplasia (HP:0100842)2.00567221
123Abnormality of cells of the erythroid lineage (HP:0012130)1.99779069
124Abnormal lung lobation (HP:0002101)1.99448353
125Pancreatic islet-cell hyperplasia (HP:0004510)1.98335189
126Absent eyelashes (HP:0000561)1.97262673
127Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.95939812
128Embryonal neoplasm (HP:0002898)1.95056366
129Uterine neoplasm (HP:0010784)1.94014240
130Angiofibromas (HP:0010615)1.93937365
131Adenoma sebaceum (HP:0009720)1.93937365
132Atrophy/Degeneration involving motor neurons (HP:0007373)1.93319456
133Proximal placement of thumb (HP:0009623)1.93135450
134Neoplasm of the colon (HP:0100273)1.92879082
135Coronal craniosynostosis (HP:0004440)1.92525299
136Aplasia involving bones of the extremities (HP:0009825)1.92485051
137Aplasia involving bones of the upper limbs (HP:0009823)1.92485051
138Aplasia of the phalanges of the hand (HP:0009802)1.92485051
139Abnormality of the middle phalanges of the toes (HP:0010183)1.91927949
140Cellular immunodeficiency (HP:0005374)1.91085786
141Overriding aorta (HP:0002623)1.90814575
142Absent eyebrow (HP:0002223)1.90792341
143Triphalangeal thumb (HP:0001199)1.90577539
144Squamous cell carcinoma (HP:0002860)1.90350435
145Duodenal stenosis (HP:0100867)1.90220303
146Small intestinal stenosis (HP:0012848)1.90220303
147Ectopic kidney (HP:0000086)1.89153379
148Preaxial foot polydactyly (HP:0001841)1.88627949
149Abnormality of the duodenum (HP:0002246)1.88064540
150Abnormal hair whorl (HP:0010721)1.87905324
151Facial hemangioma (HP:0000329)1.87801420
152Cleft eyelid (HP:0000625)1.86855270
153Short thumb (HP:0009778)1.86826083
154Tongue fasciculations (HP:0001308)1.86804995
155Abnormality of the lacrimal duct (HP:0011481)1.86460179
156Partial duplication of the phalanx of hand (HP:0009999)1.86140183
157Preauricular skin tag (HP:0000384)1.86008875
158Trigonocephaly (HP:0000243)1.84885275
159Clitoromegaly (HP:0000057)1.83718265
160Abnormality of the clitoris (HP:0000056)1.83206402
161Abnormality of serum amino acid levels (HP:0003112)1.78837843

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.42403969
2CDK124.15446305
3WEE14.09503312
4CDC73.82554228
5VRK23.36174427
6EPHA23.32601484
7TAF13.19258296
8SMG13.08434345
9TTK2.91712844
10CDK192.84400997
11NEK12.66042815
12CDK72.41242275
13NEK22.38826537
14TSSK62.28025076
15TNIK2.26980920
16PLK12.23308323
17EIF2AK12.12040929
18SRPK12.11359983
19RPS6KB21.96970930
20PNCK1.93033754
21LATS21.91420617
22TESK21.79060482
23FGFR21.77551923
24CHEK21.67160101
25BRD41.63769261
26ATR1.59273279
27AKT31.57389342
28PASK1.53111620
29MKNK11.52773968
30PLK31.52239124
31DYRK31.49473756
32AURKB1.48073107
33AURKA1.45209835
34PLK41.44236664
35CHEK11.44126763
36ALK1.32619655
37CAMK1D1.32102686
38PAK41.31875953
39STK101.30923241
40MAP3K81.30214862
41MKNK21.29574532
42NUAK11.24685160
43CDK41.24180036
44STK38L1.20379215
45TLK11.19509050
46ICK1.18616598
47VRK11.16388242
48STK241.14403668
49KDR1.12454184
50CAMK1G1.12246222
51CDK21.09920479
52EIF2AK31.07798868
53STK31.06896549
54FGFR41.04201196
55PRKCI1.01276459
56ACVR1B1.00713265
57ATM1.00144066
58CSNK1G10.99459375
59MAPKAPK30.95164316
60FLT30.92930801
61NME20.91859586
62BRSK20.89781367
63STK40.89708106
64NME10.89620634
65MTOR0.85175135
66CDK60.84104264
67CSNK2A20.82271266
68GRK60.80300508
69CSNK1E0.79836703
70WNK30.79774589
71PIM10.79580395
72OXSR10.77855357
73MAP3K100.77245991
74MET0.76065317
75SCYL20.75311592
76TYRO30.74665541
77DYRK20.73453606
78BCKDK0.73139130
79CDK10.72907981
80PAK10.72074367
81DMPK0.69017926
82TGFBR10.67293715
83CSNK2A10.66981468
84CSNK1G20.66617966
85CASK0.66275920
86MAP3K110.64599610
87NLK0.63962266
88CSNK1G30.62045512
89AKT20.61080219
90PDK20.60657645
91MELK0.59932165
92TIE10.56979646
93RPS6KA40.54578038
94DAPK10.53807483
95PRKG20.53674118
96PDK30.52098667
97PDK40.52098667
98NTRK10.51097980
99FGFR10.48434819
100BRSK10.48390448
101ERBB40.48084111
102PBK0.47918676
103CSNK1D0.47431289
104TESK10.46403552
105DDR20.46092895
106BRAF0.45626944
107BMX0.45125772
108ZAK0.44719656
109LATS10.44695744
110EIF2AK20.43841690
111PRKDC0.43668571
112MAP3K90.43183029
113BCR0.43066023
114CSNK1A1L0.42659335
115EGFR0.41565716
116MATK0.40683360
117EEF2K0.39955641
118MAPK140.39636183
119YES10.38050440
120DYRK1A0.37000827
121CDK90.36871451
122GSK3B0.35961683
123MST40.34765557
124MAPK10.33915031
125MAPK90.33750530
126CDK11A0.33452717
127CDK150.29596837
128MAPK100.29565964
129CDK180.28691243
130TRIM280.28643920
131AKT10.26648469
132TAOK20.24505318
133RPS6KA50.23134631
134RPS6KA10.23105580
135STK160.18794711

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.68452387
2DNA replication_Homo sapiens_hsa030304.59412624
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.32444686
4RNA transport_Homo sapiens_hsa030133.48571467
5Spliceosome_Homo sapiens_hsa030403.47550108
6RNA polymerase_Homo sapiens_hsa030203.35833367
7One carbon pool by folate_Homo sapiens_hsa006703.33604942
8Ribosome_Homo sapiens_hsa030103.22207687
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.03989268
10Base excision repair_Homo sapiens_hsa034102.90709000
11Homologous recombination_Homo sapiens_hsa034402.78034657
12Nucleotide excision repair_Homo sapiens_hsa034202.72203919
13Proteasome_Homo sapiens_hsa030502.55321654
14Cell cycle_Homo sapiens_hsa041102.43188175
15Fanconi anemia pathway_Homo sapiens_hsa034602.32375614
16Pyrimidine metabolism_Homo sapiens_hsa002402.19153416
17mRNA surveillance pathway_Homo sapiens_hsa030152.12204365
18RNA degradation_Homo sapiens_hsa030181.86218456
19Basal transcription factors_Homo sapiens_hsa030221.78325857
20Non-homologous end-joining_Homo sapiens_hsa034501.71026496
21p53 signaling pathway_Homo sapiens_hsa041151.62830179
22Biosynthesis of amino acids_Homo sapiens_hsa012301.44072043
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.35683505
24Steroid biosynthesis_Homo sapiens_hsa001001.30552215
25Cyanoamino acid metabolism_Homo sapiens_hsa004601.14808257
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.13881404
27Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.10684742
28Basal cell carcinoma_Homo sapiens_hsa052171.10426496
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.10115845
30Purine metabolism_Homo sapiens_hsa002301.07580077
31Folate biosynthesis_Homo sapiens_hsa007901.02867511
32Oocyte meiosis_Homo sapiens_hsa041141.02403754
33Hippo signaling pathway_Homo sapiens_hsa043901.02048955
34Selenocompound metabolism_Homo sapiens_hsa004501.02026961
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.98737889
36Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98019542
37Epstein-Barr virus infection_Homo sapiens_hsa051690.96338824
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.94381261
39Fructose and mannose metabolism_Homo sapiens_hsa000510.88852355
40Hedgehog signaling pathway_Homo sapiens_hsa043400.87458038
41Vitamin digestion and absorption_Homo sapiens_hsa049770.85983552
42Thyroid cancer_Homo sapiens_hsa052160.82483595
43Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80826271
44Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80600472
45TGF-beta signaling pathway_Homo sapiens_hsa043500.78045458
46Viral carcinogenesis_Homo sapiens_hsa052030.73590181
47Systemic lupus erythematosus_Homo sapiens_hsa053220.73527305
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.73024273
49Vitamin B6 metabolism_Homo sapiens_hsa007500.72356531
50Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71855790
51MicroRNAs in cancer_Homo sapiens_hsa052060.70583966
52Propanoate metabolism_Homo sapiens_hsa006400.70564276
53Sulfur relay system_Homo sapiens_hsa041220.70219204
54Carbon metabolism_Homo sapiens_hsa012000.69947669
55Notch signaling pathway_Homo sapiens_hsa043300.68627665
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67561773
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.66971438
58Fatty acid elongation_Homo sapiens_hsa000620.65695998
59Protein export_Homo sapiens_hsa030600.63833891
60Glutathione metabolism_Homo sapiens_hsa004800.63534346
61Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60010307
62Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58818665
63Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.55666800
64Pentose phosphate pathway_Homo sapiens_hsa000300.53171521
65Adherens junction_Homo sapiens_hsa045200.53129045
66HTLV-I infection_Homo sapiens_hsa051660.52847694
67Herpes simplex infection_Homo sapiens_hsa051680.52549507
68Bladder cancer_Homo sapiens_hsa052190.51524329
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.50869070
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49763661
71Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.49403205
72Arginine and proline metabolism_Homo sapiens_hsa003300.48417970
73Arginine biosynthesis_Homo sapiens_hsa002200.48049049
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47884251
75mTOR signaling pathway_Homo sapiens_hsa041500.47306827
76Tight junction_Homo sapiens_hsa045300.47218244
77Galactose metabolism_Homo sapiens_hsa000520.43856881
78Huntingtons disease_Homo sapiens_hsa050160.40262951
79Wnt signaling pathway_Homo sapiens_hsa043100.40240237
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.39108337
81Antigen processing and presentation_Homo sapiens_hsa046120.36411163
82Pathways in cancer_Homo sapiens_hsa052000.35361112
83Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33757752
84Fatty acid metabolism_Homo sapiens_hsa012120.32568684
85Small cell lung cancer_Homo sapiens_hsa052220.32475981
86Colorectal cancer_Homo sapiens_hsa052100.31592943
87Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30916131
88Parkinsons disease_Homo sapiens_hsa050120.29342205
89Lysine degradation_Homo sapiens_hsa003100.27900120
90Melanoma_Homo sapiens_hsa052180.27381022
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.26844256
92HIF-1 signaling pathway_Homo sapiens_hsa040660.26347959
93Endometrial cancer_Homo sapiens_hsa052130.26115941
94Melanogenesis_Homo sapiens_hsa049160.25433255
95Taste transduction_Homo sapiens_hsa047420.25373897
96Glucagon signaling pathway_Homo sapiens_hsa049220.24012673
97Linoleic acid metabolism_Homo sapiens_hsa005910.23023579
98Renin-angiotensin system_Homo sapiens_hsa046140.22153065
99Axon guidance_Homo sapiens_hsa043600.21080912
100Arachidonic acid metabolism_Homo sapiens_hsa005900.19004723
101Fat digestion and absorption_Homo sapiens_hsa049750.18897483
102N-Glycan biosynthesis_Homo sapiens_hsa005100.18805086
103Metabolic pathways_Homo sapiens_hsa011000.18341810
104Legionellosis_Homo sapiens_hsa051340.18104081
105beta-Alanine metabolism_Homo sapiens_hsa004100.17578309
106Alcoholism_Homo sapiens_hsa050340.17234213
107Nicotine addiction_Homo sapiens_hsa050330.15787059
108Ether lipid metabolism_Homo sapiens_hsa005650.15780372
109Apoptosis_Homo sapiens_hsa042100.13191566
110Longevity regulating pathway - mammal_Homo sapiens_hsa042110.12304956
111Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.10862512
112alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.08782500
113Regulation of actin cytoskeleton_Homo sapiens_hsa048100.08659994
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.08437737
115Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.08339391
116PI3K-Akt signaling pathway_Homo sapiens_hsa041510.08225289
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.08085363
118Prostate cancer_Homo sapiens_hsa052150.07467144
119Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.07045078
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07030914
121Phenylalanine metabolism_Homo sapiens_hsa003600.06335993
122Pyruvate metabolism_Homo sapiens_hsa006200.06194315
123Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.05586850
124Acute myeloid leukemia_Homo sapiens_hsa052210.05349208
125Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.03237215
126Prion diseases_Homo sapiens_hsa050200.02675697
127Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.02137484
128Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.01912544
129Fatty acid biosynthesis_Homo sapiens_hsa000610.00923391

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