ZSCAN18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)6.91584923
2replication fork processing (GO:0031297)5.27540901
3proline metabolic process (GO:0006560)5.07870863
4establishment of protein localization to mitochondrial membrane (GO:0090151)4.99382940
5embryonic process involved in female pregnancy (GO:0060136)4.98016550
6transcription from mitochondrial promoter (GO:0006390)4.92387893
7positive regulation of protein homooligomerization (GO:0032464)4.88012069
8single strand break repair (GO:0000012)4.79716745
9postsynaptic membrane organization (GO:0001941)4.69642912
10central nervous system myelination (GO:0022010)4.46931321
11axon ensheathment in central nervous system (GO:0032291)4.46931321
12regulation of protein homooligomerization (GO:0032462)4.46277940
13oxidative demethylation (GO:0070989)4.45984454
14membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.43626832
15dendritic spine morphogenesis (GO:0060997)4.28966700
16establishment of apical/basal cell polarity (GO:0035089)4.26591585
17DNA strand renaturation (GO:0000733)4.25897306
18glutamate secretion (GO:0014047)4.25763300
19synaptic vesicle docking involved in exocytosis (GO:0016081)4.22545649
20axonemal dynein complex assembly (GO:0070286)4.18399266
21synaptic vesicle endocytosis (GO:0048488)4.15800321
22maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.14893032
23establishment of monopolar cell polarity (GO:0061162)4.11353289
24establishment or maintenance of monopolar cell polarity (GO:0061339)4.11353289
25regulation of synaptic vesicle exocytosis (GO:2000300)4.06044156
26pyrimidine nucleobase catabolic process (GO:0006208)4.05980613
27regulation of cAMP-dependent protein kinase activity (GO:2000479)4.00751994
28cell migration in hindbrain (GO:0021535)3.94099850
29neuronal ion channel clustering (GO:0045161)3.91383582
30negative regulation of JAK-STAT cascade (GO:0046426)3.87289128
31auditory behavior (GO:0031223)3.87151292
32axonal fasciculation (GO:0007413)3.85949044
33spliceosomal tri-snRNP complex assembly (GO:0000244)3.85342007
34presynaptic membrane organization (GO:0097090)3.82347329
35mitochondrial DNA metabolic process (GO:0032042)3.78051773
36presynaptic membrane assembly (GO:0097105)3.76654498
37histone H4-K12 acetylation (GO:0043983)3.73494005
38regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.71626347
39ionotropic glutamate receptor signaling pathway (GO:0035235)3.71324689
40regulation of integrin activation (GO:0033623)3.70624736
41somatic diversification of immune receptors via somatic mutation (GO:0002566)3.70105734
42somatic hypermutation of immunoglobulin genes (GO:0016446)3.70105734
43viral mRNA export from host cell nucleus (GO:0046784)3.70014163
44regulation of synaptic vesicle transport (GO:1902803)3.66820201
45synaptic vesicle exocytosis (GO:0016079)3.62996251
46neuromuscular process controlling posture (GO:0050884)3.62127733
47DNA deamination (GO:0045006)3.60715660
48cilium movement (GO:0003341)3.57877906
49neuronal action potential propagation (GO:0019227)3.57829880
50positive regulation of dendritic spine morphogenesis (GO:0061003)3.57281409
51synaptic transmission, glutamatergic (GO:0035249)3.57145876
52exploration behavior (GO:0035640)3.54291418
53negative regulation of Ras GTPase activity (GO:0034261)3.52143212
54neuron recognition (GO:0008038)3.51293238
55regulation of synapse structural plasticity (GO:0051823)3.49814529
56epithelial cilium movement (GO:0003351)3.49604195
57neurotransmitter secretion (GO:0007269)3.48754845
58cellular potassium ion homeostasis (GO:0030007)3.48491905
59poly(A)+ mRNA export from nucleus (GO:0016973)3.44171919
60neurotransmitter-gated ion channel clustering (GO:0072578)3.43783101
61negative regulation of protein oligomerization (GO:0032460)3.42067814
62convergent extension (GO:0060026)3.40084751
63vocalization behavior (GO:0071625)3.37788172
64positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.36993647
65cilium or flagellum-dependent cell motility (GO:0001539)3.34605991
66regulation of short-term neuronal synaptic plasticity (GO:0048172)3.33132465
67G1 DNA damage checkpoint (GO:0044783)3.32946054
68cerebellar granule cell differentiation (GO:0021707)3.31038804
69response to auditory stimulus (GO:0010996)3.27505173
70establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.27295577
71mitochondrion transport along microtubule (GO:0047497)3.27295577
72positive regulation of synapse maturation (GO:0090129)3.24111632
73nucleobase catabolic process (GO:0046113)3.23793413
74regulation of respiratory system process (GO:0044065)3.23549355
75resolution of meiotic recombination intermediates (GO:0000712)3.22668355
76neuron cell-cell adhesion (GO:0007158)3.19966325
77cellular response to ATP (GO:0071318)3.15070993
78regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.14645492
79mechanosensory behavior (GO:0007638)3.14419637
80maturation of 5.8S rRNA (GO:0000460)3.13720521
81regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.12445975
82response to pheromone (GO:0019236)3.11871715
83epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.11866981
84glutamate receptor signaling pathway (GO:0007215)3.10312678
85regulation of neuronal synaptic plasticity (GO:0048168)3.09846873
86respiratory system process (GO:0003016)3.09474112
87regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.05702816
88establishment of mitochondrion localization (GO:0051654)3.02680335
89negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.02397531
90regulation of cilium movement (GO:0003352)3.01639480
91cullin deneddylation (GO:0010388)3.00653595
92neuron-neuron synaptic transmission (GO:0007270)2.99599092
93glial cell migration (GO:0008347)2.99373423
94positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.98458598
95gamma-aminobutyric acid transport (GO:0015812)2.97821030
96DNA double-strand break processing (GO:0000729)2.97363614
97cerebellar Purkinje cell differentiation (GO:0021702)2.96076178
98positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.95942200
99positive regulation of synapse assembly (GO:0051965)2.93994370
100mitotic G1 DNA damage checkpoint (GO:0031571)2.93299621
101regulation of RNA export from nucleus (GO:0046831)2.92332172
102membrane depolarization during action potential (GO:0086010)2.90956680
103synapse assembly (GO:0007416)2.90469875
104protein localization to synapse (GO:0035418)2.88331923
105positive regulation of membrane potential (GO:0045838)2.87919991
106DNA integration (GO:0015074)2.87413790
107negative regulation of cell cycle arrest (GO:0071157)2.86388470
108positive regulation of dendritic spine development (GO:0060999)2.86031363
109cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.85958609
110sodium ion export (GO:0071436)2.85067037
111locomotory exploration behavior (GO:0035641)2.84731523
112double-strand break repair via nonhomologous end joining (GO:0006303)2.84429050
113non-recombinational repair (GO:0000726)2.84429050
114regulation of synapse maturation (GO:0090128)2.82736704
115histone arginine methylation (GO:0034969)2.82039374
116regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.81786579
117adult walking behavior (GO:0007628)2.80917013
118neuromuscular process controlling balance (GO:0050885)2.80485220
119regulation of mitochondrial depolarization (GO:0051900)2.79985689
120regulation of neurotransmitter secretion (GO:0046928)2.79197067
121auditory receptor cell stereocilium organization (GO:0060088)2.77990417
122regulation of excitatory postsynaptic membrane potential (GO:0060079)2.77443308
123potassium ion homeostasis (GO:0055075)2.76824330
124negative regulation of synaptic transmission, GABAergic (GO:0032229)2.75382394
125mRNA cleavage (GO:0006379)2.75317210
126behavioral response to nicotine (GO:0035095)2.75069383
127regulation of NFAT protein import into nucleus (GO:0051532)2.75055019
128regulation of translational fidelity (GO:0006450)2.74978874
129regulation of respiratory gaseous exchange (GO:0043576)2.74768805
130regulation of glutamate receptor signaling pathway (GO:1900449)2.74654040
131dendritic spine organization (GO:0097061)2.73776204
132neuromuscular synaptic transmission (GO:0007274)2.73652840
133regulation of membrane depolarization (GO:0003254)2.73645779
134neurotransmitter transport (GO:0006836)2.73561604
135potassium ion import (GO:0010107)2.73422571
136DNA demethylation (GO:0080111)2.73141170
137labyrinthine layer development (GO:0060711)2.72660096
138synaptic vesicle maturation (GO:0016188)2.72586833
139regulation of neurotransmitter levels (GO:0001505)2.72482494
140signal complex assembly (GO:0007172)2.72441854
141head development (GO:0060322)2.71319327
142regulation of postsynaptic membrane potential (GO:0060078)2.71181671
143regulation of microtubule-based movement (GO:0060632)2.71040228
144negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.70245819
145negative regulation of mRNA processing (GO:0050686)2.69698548
146regulation of vesicle fusion (GO:0031338)2.68923275
147left/right pattern formation (GO:0060972)2.68296705
148transmission of nerve impulse (GO:0019226)2.67729562
149regulation of voltage-gated calcium channel activity (GO:1901385)2.67683758
150regulation of long-term neuronal synaptic plasticity (GO:0048169)2.67601141
151spinal cord development (GO:0021510)2.67580645
152negative regulation of axonogenesis (GO:0050771)2.66001780
153central nervous system projection neuron axonogenesis (GO:0021952)2.65515792
154regulation of neurotransmitter transport (GO:0051588)2.65159894
155synapse organization (GO:0050808)2.64911281
156neuromuscular process (GO:0050905)2.64643278
157regulation of protein oligomerization (GO:0032459)2.63964088
158cell communication by electrical coupling (GO:0010644)2.62890322
159peptidyl-arginine N-methylation (GO:0035246)2.62372971
160peptidyl-arginine methylation (GO:0018216)2.62372971
161membrane depolarization (GO:0051899)2.62130531
162negative regulation of heart rate (GO:0010459)2.61555731
163negative regulation of appetite (GO:0032099)2.59756625
164negative regulation of response to food (GO:0032096)2.59756625
165cerebral cortex radially oriented cell migration (GO:0021799)2.59478223
166peptidyl-arginine omega-N-methylation (GO:0035247)2.59132302
167cell differentiation in hindbrain (GO:0021533)2.58672460
168regulation of synaptic transmission, glutamatergic (GO:0051966)2.58332726
169regulation of DNA damage checkpoint (GO:2000001)2.57981401
170mitotic G1/S transition checkpoint (GO:0044819)2.56662501
171nonmotile primary cilium assembly (GO:0035058)2.56017570
172embryonic placenta development (GO:0001892)2.55712616
173adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.55390252
174DNA ligation (GO:0006266)2.55047714
175N-glycan processing (GO:0006491)2.54382190
176positive regulation of circadian rhythm (GO:0042753)2.54314258
177layer formation in cerebral cortex (GO:0021819)2.53835262
178base-excision repair (GO:0006284)2.52407199

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.37980825
2ZFP281_18358816_ChIP-ChIP_MESCs_Mouse3.49266738
3SMAD3_22036565_ChIP-Seq_ESCs_Mouse3.14309934
4ERG_21242973_ChIP-ChIP_JURKAT_Human2.95721640
5SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.82864942
6EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.82193760
7EZH2_27294783_Chip-Seq_ESCs_Mouse2.65724168
8NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.60412444
9SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.53053678
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.50536843
11CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.50431108
12REST_21632747_ChIP-Seq_MESCs_Mouse2.39473490
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.38342606
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.31661618
15SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.28073058
16RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.27248973
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26273521
18REST_18959480_ChIP-ChIP_MESCs_Mouse2.17340143
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.16620957
20POU5F1_16518401_ChIP-PET_MESCs_Mouse2.15156732
21KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.14746576
22KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.14746576
23KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.14746576
24SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.13141331
25NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.05643116
26ZFP281_18757296_ChIP-ChIP_E14_Mouse2.03004880
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.99480877
28RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.97368542
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.95977847
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.89907259
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.84508355
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.84078250
33TCF3_18692474_ChIP-Seq_MESCs_Mouse1.74755528
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.63184499
35ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.62390952
36RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61884668
37DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.58649850
38ZFP281_27345836_Chip-Seq_ESCs_Mouse1.56598599
39RING1B_27294783_Chip-Seq_NPCs_Mouse1.55730656
40DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.55092069
41ESR1_15608294_ChIP-ChIP_MCF-7_Human1.51298423
42NANOG_21062744_ChIP-ChIP_HESCs_Human1.50945771
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.49693263
44NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.49046583
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48406954
46GBX2_23144817_ChIP-Seq_PC3_Human1.45395773
47RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44927988
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42947653
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.40217353
50PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.38223841
51SOX2_18555785_ChIP-Seq_MESCs_Mouse1.37911025
52NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.37358249
53EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.35486962
54NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.33701728
55TET1_21490601_ChIP-Seq_MESCs_Mouse1.32897586
56RNF2_27304074_Chip-Seq_NSC_Mouse1.31893460
57CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.31469102
58KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.31326478
59SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.31062272
60EZH2_27304074_Chip-Seq_ESCs_Mouse1.30831519
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.30289946
62TP53_20018659_ChIP-ChIP_R1E_Mouse1.29282166
63LXR_22292898_ChIP-Seq_THP-1_Human1.28673283
64KDM2B_26808549_Chip-Seq_K562_Human1.27113917
65RNF2_27304074_Chip-Seq_ESCs_Mouse1.27005343
66DNAJC2_21179169_ChIP-ChIP_NT2_Human1.26714512
67WT1_25993318_ChIP-Seq_PODOCYTE_Human1.21633423
68JARID2_20075857_ChIP-Seq_MESCs_Mouse1.20651134
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20438544
70JARID2_20064375_ChIP-Seq_MESCs_Mouse1.18422516
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.17938310
72* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.17830712
73CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.17680185
74MYC_19079543_ChIP-ChIP_MESCs_Mouse1.17601642
75STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17159056
76ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.16867526
77CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16826956
78SUZ12_27294783_Chip-Seq_ESCs_Mouse1.16785335
79TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.16509363
80POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.15961793
81MYC_18555785_ChIP-Seq_MESCs_Mouse1.14609774
82CTBP1_25329375_ChIP-Seq_LNCAP_Human1.14603286
83BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12421255
84HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.11491041
85NANOG_16518401_ChIP-PET_MESCs_Mouse1.11010873
86SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.10893833
87TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10293574
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10293574
89CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09851211
90DROSHA_22980978_ChIP-Seq_HELA_Human1.09735440
91CTCF_27219007_Chip-Seq_Bcells_Human1.09394912
92TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09270700
93TCF3_18692474_ChIP-Seq_MEFs_Mouse1.09216491
94ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08301191
95POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.06789986
96PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.06593050
97SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.05772552
98AR_19668381_ChIP-Seq_PC3_Human1.04557051
99CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.04184998
100ZNF274_21170338_ChIP-Seq_K562_Hela1.03896880
101TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03674382
102* RING1B_27294783_Chip-Seq_ESCs_Mouse1.03566041
103TET1_21451524_ChIP-Seq_MESCs_Mouse1.03066171
104E2F1_17053090_ChIP-ChIP_MCF-7_Human1.02415645
105SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.01751199
106AR_21572438_ChIP-Seq_LNCaP_Human1.01193986
107PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.00965254
108NANOG_18692474_ChIP-Seq_MESCs_Mouse1.00506213
109ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99519487
110TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99131844
111SOX2_18692474_ChIP-Seq_MESCs_Mouse0.98613515
112ZFP57_27257070_Chip-Seq_ESCs_Mouse0.97027145
113PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96173066
114P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95972439
115POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.94163281
116OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.94009420
117GATA1_26923725_Chip-Seq_HPCs_Mouse0.93914351
118YY1_21170310_ChIP-Seq_MESCs_Mouse0.93561373
119EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.93066784
120CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93048173
121MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93026623
122POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.92900150
123GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91595175
124SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.91328076
125EZH2_18974828_ChIP-Seq_MESCs_Mouse0.90810653
126RNF2_18974828_ChIP-Seq_MESCs_Mouse0.90810653
127SMAD3_21741376_ChIP-Seq_ESCs_Human0.90156260
128SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.89867137
129HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.89155358
130TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88899005
131MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88489703
132SMAD4_21799915_ChIP-Seq_A2780_Human0.86974706
133CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.86441046
134OCT4_19829295_ChIP-Seq_ESCs_Human0.86386815
135SOX2_21211035_ChIP-Seq_LN229_Gbm0.85540223
136WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.84680042
137PIAS1_25552417_ChIP-Seq_VCAP_Human0.82073241
138SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.81831961
139RBPJ_22232070_ChIP-Seq_NCS_Mouse0.80730625
140TOP2B_26459242_ChIP-Seq_MCF-7_Human0.80662923
141SMAD3_21741376_ChIP-Seq_EPCs_Human0.80554041
142KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80506077
143ISL1_27105846_Chip-Seq_CPCs_Mouse0.80362034
144LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79739995
145SMC4_20622854_ChIP-Seq_HELA_Human0.79337902
146TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.77453466
147SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.76997921
148KLF4_19829295_ChIP-Seq_ESCs_Human0.76702122
149SMAD4_21741376_ChIP-Seq_HESCs_Human0.76392462
150KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.74236898
151SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.72615629
152P68_20966046_ChIP-Seq_HELA_Human0.71840831
153MYC_27129775_Chip-Seq_CORNEA_Mouse0.71781257
154NR3C1_21868756_ChIP-Seq_MCF10A_Human0.71087293

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.63598239
2MP0008057_abnormal_DNA_replication3.53993348
3MP0004233_abnormal_muscle_weight3.13282906
4MP0005171_absent_coat_pigmentation3.10381402
5MP0003880_abnormal_central_pattern2.70490930
6MP0008877_abnormal_DNA_methylation2.55927275
7MP0003635_abnormal_synaptic_transmissio2.51822885
8MP0005645_abnormal_hypothalamus_physiol2.48747559
9MP0002063_abnormal_learning/memory/cond2.34848529
10MP0010030_abnormal_orbit_morphology2.33705906
11MP0003890_abnormal_embryonic-extraembry2.27728005
12MP0002572_abnormal_emotion/affect_behav2.24312075
13MP0009046_muscle_twitch2.18236675
14MP0004133_heterotaxia2.16756201
15MP0008995_early_reproductive_senescence2.11479773
16MP0002064_seizures2.07248836
17MP0009278_abnormal_bone_marrow2.07027111
18MP0006072_abnormal_retinal_apoptosis2.03648856
19MP0001984_abnormal_olfaction2.00810051
20MP0003283_abnormal_digestive_organ1.99998735
21MP0000566_synostosis1.99557006
22MP0000778_abnormal_nervous_system1.97150720
23MP0009745_abnormal_behavioral_response1.96319940
24MP0001968_abnormal_touch/_nociception1.89595424
25MP0009379_abnormal_foot_pigmentation1.88718727
26MP0004270_analgesia1.79294542
27MP0002653_abnormal_ependyma_morphology1.77078164
28MP0003122_maternal_imprinting1.75401677
29MP0002733_abnormal_thermal_nociception1.71178442
30MP0002736_abnormal_nociception_after1.69352925
31MP0001440_abnormal_grooming_behavior1.64945076
32MP0001502_abnormal_circadian_rhythm1.63805193
33MP0006276_abnormal_autonomic_nervous1.63401741
34MP0003119_abnormal_digestive_system1.62816405
35MP0005423_abnormal_somatic_nervous1.59905742
36MP0001970_abnormal_pain_threshold1.54795884
37MP0000955_abnormal_spinal_cord1.54577212
38MP0004142_abnormal_muscle_tone1.54567872
39MP0002184_abnormal_innervation1.54087951
40MP0005174_abnormal_tail_pigmentation1.53959021
41MP0002638_abnormal_pupillary_reflex1.49784064
42MP0003329_amyloid_beta_deposits1.49241297
43MP0002272_abnormal_nervous_system1.45879277
44MP0004742_abnormal_vestibular_system1.44232206
45MP0003879_abnormal_hair_cell1.42702144
46MP0000015_abnormal_ear_pigmentation1.41729020
47MP0002734_abnormal_mechanical_nocicepti1.38221373
48MP0004811_abnormal_neuron_physiology1.38056367
49MP0005394_taste/olfaction_phenotype1.33443689
50MP0005499_abnormal_olfactory_system1.33443689
51MP0001486_abnormal_startle_reflex1.29088082
52MP0002249_abnormal_larynx_morphology1.27721651
53MP0010094_abnormal_chromosome_stability1.26389844
54MP0005646_abnormal_pituitary_gland1.25973589
55MP0005551_abnormal_eye_electrophysiolog1.25227677
56MP0002067_abnormal_sensory_capabilities1.23301329
57MP0000026_abnormal_inner_ear1.23266529
58MP0003123_paternal_imprinting1.22818152
59MP0003787_abnormal_imprinting1.19406077
60MP0002152_abnormal_brain_morphology1.17651011
61MP0002882_abnormal_neuron_morphology1.17523512
62MP0002557_abnormal_social/conspecific_i1.15993493
63MP0005386_behavior/neurological_phenoty1.14932919
64MP0004924_abnormal_behavior1.14932919
65MP0009780_abnormal_chondrocyte_physiolo1.14257722
66MP0002009_preneoplasia1.13836511
67MP0006292_abnormal_olfactory_placode1.13755718
68MP0001963_abnormal_hearing_physiology1.13704629
69MP0003861_abnormal_nervous_system1.13668566
70MP0003878_abnormal_ear_physiology1.12999164
71MP0005377_hearing/vestibular/ear_phenot1.12999164
72MP0002066_abnormal_motor_capabilities/c1.11736763
73MP0002084_abnormal_developmental_patter1.11071068
74MP0003786_premature_aging1.05731105
75MP0003137_abnormal_impulse_conducting1.05682434
76MP0001905_abnormal_dopamine_level1.05149858
77MP0008789_abnormal_olfactory_epithelium1.04246554
78MP0005253_abnormal_eye_physiology1.02133052
79MP0002282_abnormal_trachea_morphology1.02064545
80MP0001501_abnormal_sleep_pattern1.01405015
81MP0003121_genomic_imprinting1.01402009
82MP0001529_abnormal_vocalization1.01088076
83MP0003172_abnormal_lysosome_physiology1.00263299
84MP0008569_lethality_at_weaning0.99929444
85MP0003136_yellow_coat_color0.99105224
86MP0000631_abnormal_neuroendocrine_gland0.98931138
87MP0000751_myopathy0.98128182
88MP0008058_abnormal_DNA_repair0.95063938
89MP0003938_abnormal_ear_development0.94989792
90MP0002229_neurodegeneration0.94747553
91MP0002822_catalepsy0.94703194
92MP0002085_abnormal_embryonic_tissue0.91654785
93MP0001485_abnormal_pinna_reflex0.91504605
94MP0001299_abnormal_eye_distance/0.91453021
95MP0002909_abnormal_adrenal_gland0.91333580
96MP0003755_abnormal_palate_morphology0.89795300
97MP0003634_abnormal_glial_cell0.87959574
98MP0003631_nervous_system_phenotype0.87810917
99MP0002751_abnormal_autonomic_nervous0.87477151
100MP0001697_abnormal_embryo_size0.85410623
101MP0004885_abnormal_endolymph0.84970298
102MP0001293_anophthalmia0.83784796
103MP0002116_abnormal_craniofacial_bone0.83601078
104MP0004197_abnormal_fetal_growth/weight/0.82041266
105MP0001340_abnormal_eyelid_morphology0.81587829
106MP0000639_abnormal_adrenal_gland0.81103273
107MP0002086_abnormal_extraembryonic_tissu0.80946295
108MP0002752_abnormal_somatic_nervous0.80751198
109MP0010768_mortality/aging0.79365443
110MP0004957_abnormal_blastocyst_morpholog0.78523139
111MP0002069_abnormal_eating/drinking_beha0.78263961
112MP0002837_dystrophic_cardiac_calcinosis0.78198574
113MP0002114_abnormal_axial_skeleton0.78124496
114MP0004130_abnormal_muscle_cell0.77804049
115MP0008932_abnormal_embryonic_tissue0.77167519
116MP0010769_abnormal_survival0.76845260
117MP0000579_abnormal_nail_morphology0.76525683
118MP0002735_abnormal_chemical_nociception0.75784064
119MP0003935_abnormal_craniofacial_develop0.74692389
120MP0010770_preweaning_lethality0.73821971
121MP0002082_postnatal_lethality0.73821971
122MP0005195_abnormal_posterior_eye0.72472214
123MP0003690_abnormal_glial_cell0.72303175
124MP0004145_abnormal_muscle_electrophysio0.72117913
125MP0003698_abnormal_male_reproductive0.71863381
126MP0003633_abnormal_nervous_system0.71736605
127MP0000049_abnormal_middle_ear0.70884012
128MP0001188_hyperpigmentation0.70650824
129MP0000462_abnormal_digestive_system0.70484131
130MP0001943_abnormal_respiration0.70258115
131MP0001177_atelectasis0.69731790
132MP0002928_abnormal_bile_duct0.67959705
133MP0003632_abnormal_nervous_system0.67890821
134MP0003011_delayed_dark_adaptation0.65307431
135MP0002876_abnormal_thyroid_physiology0.65177151
136MP0004043_abnormal_pH_regulation0.62940930
137MP0000534_abnormal_ureter_morphology0.61613029
138MP0003942_abnormal_urinary_system0.60746528

Predicted human phenotypes

RankGene SetZ-score
1Annular pancreas (HP:0001734)4.47616019
2Facial hemangioma (HP:0000329)4.43079945
3Focal motor seizures (HP:0011153)4.19634232
4Abnormal ciliary motility (HP:0012262)4.07692501
5Rib fusion (HP:0000902)3.96321773
6Abnormal respiratory motile cilium physiology (HP:0012261)3.91866313
7Concave nail (HP:0001598)3.86334494
8Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.84334060
9Myokymia (HP:0002411)3.84078981
10Dynein arm defect of respiratory motile cilia (HP:0012255)3.68355954
11Absent/shortened dynein arms (HP:0200106)3.68355954
12Abnormality of the labia minora (HP:0012880)3.64671277
13Progressive cerebellar ataxia (HP:0002073)3.61786852
14Rectal fistula (HP:0100590)3.59019175
15Rectovaginal fistula (HP:0000143)3.59019175
16Turricephaly (HP:0000262)3.55122984
17Abnormal respiratory motile cilium morphology (HP:0005938)3.44023868
18Abnormal respiratory epithelium morphology (HP:0012253)3.44023868
19Atonic seizures (HP:0010819)3.43597162
20Tongue fasciculations (HP:0001308)3.29991843
21Febrile seizures (HP:0002373)3.23626286
22Rhinitis (HP:0012384)3.23069541
23Intestinal atresia (HP:0011100)3.19328312
24Intestinal fistula (HP:0100819)3.18612016
25Visual hallucinations (HP:0002367)3.14405170
26Focal seizures (HP:0007359)3.09442876
27Hypochromic microcytic anemia (HP:0004840)3.07435256
28Polyphagia (HP:0002591)3.04856908
29Sleep apnea (HP:0010535)3.03532790
30Absence seizures (HP:0002121)3.02303957
31Abnormal eating behavior (HP:0100738)3.00907057
32Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.99639817
33Vaginal fistula (HP:0004320)2.96611275
34Epileptic encephalopathy (HP:0200134)2.93642813
35Abnormality of the lower motor neuron (HP:0002366)2.93068494
36Action tremor (HP:0002345)2.92882383
37Muscle fibrillation (HP:0010546)2.90390239
38Alacrima (HP:0000522)2.90106722
39Nephronophthisis (HP:0000090)2.88948538
40Increased IgM level (HP:0003496)2.82186767
41Limb dystonia (HP:0002451)2.79492028
42Anteriorly placed anus (HP:0001545)2.77733105
43Coronal craniosynostosis (HP:0004440)2.72768107
44Short chin (HP:0000331)2.71619878
45Narrow nasal bridge (HP:0000446)2.71061683
46Gastrointestinal atresia (HP:0002589)2.69080036
47Male infertility (HP:0003251)2.68843215
48Dialeptic seizures (HP:0011146)2.68383490
49Broad alveolar ridges (HP:0000187)2.67705576
50Gait imbalance (HP:0002141)2.62846914
51Orthostatic hypotension (HP:0001278)2.61835514
52Diplopia (HP:0000651)2.57986881
53Abnormality of binocular vision (HP:0011514)2.57986881
54True hermaphroditism (HP:0010459)2.57540335
55Pancreatic fibrosis (HP:0100732)2.56412248
56Volvulus (HP:0002580)2.56015939
57Absent thumb (HP:0009777)2.50006509
58Supranuclear gaze palsy (HP:0000605)2.49980905
59Abnormality of midbrain morphology (HP:0002418)2.48575223
60Molar tooth sign on MRI (HP:0002419)2.48575223
61Abnormality of the aortic arch (HP:0012303)2.43047038
62Absent radius (HP:0003974)2.42518609
63Short humerus (HP:0005792)2.41015935
64Cerebral hypomyelination (HP:0006808)2.38230418
65Abnormality of the astrocytes (HP:0100707)2.38109621
66Astrocytoma (HP:0009592)2.38109621
67Abnormality of the renal medulla (HP:0100957)2.37363800
68Aplasia/hypoplasia of the humerus (HP:0006507)2.36615357
69Amblyopia (HP:0000646)2.36102085
70Poor suck (HP:0002033)2.35999064
71Poor coordination (HP:0002370)2.35102238
72Genetic anticipation (HP:0003743)2.33773818
73Cystic liver disease (HP:0006706)2.33434661
74Absent forearm bone (HP:0003953)2.33227082
75Aplasia involving forearm bones (HP:0009822)2.33227082
76Hemiparesis (HP:0001269)2.31640386
77Congenital hip dislocation (HP:0001374)2.29894565
78Decreased lacrimation (HP:0000633)2.29470724
79Hamartoma (HP:0010566)2.29226766
80Congenital primary aphakia (HP:0007707)2.28202533
81Clumsiness (HP:0002312)2.26770026
82Septo-optic dysplasia (HP:0100842)2.24907409
83Fetal akinesia sequence (HP:0001989)2.24803509
84Torticollis (HP:0000473)2.23880167
85Occipital encephalocele (HP:0002085)2.23487270
86Dysautonomia (HP:0002459)2.20562940
87Urinary bladder sphincter dysfunction (HP:0002839)2.20219552
88Bronchomalacia (HP:0002780)2.19641677
89Failure to thrive in infancy (HP:0001531)2.19633204
90Abnormality of the corticospinal tract (HP:0002492)2.19107575
91Esophageal atresia (HP:0002032)2.18406646
92Vaginal atresia (HP:0000148)2.17133312
93Specific learning disability (HP:0001328)2.16775609
94Megalencephaly (HP:0001355)2.16755310
95Alopecia of scalp (HP:0002293)2.16605478
96Poikiloderma (HP:0001029)2.15379638
97Spastic gait (HP:0002064)2.13720677
98Generalized tonic-clonic seizures (HP:0002069)2.12995719
99Acute lymphatic leukemia (HP:0006721)2.11766612
100Genital tract atresia (HP:0001827)2.10943531
101Neurofibrillary tangles (HP:0002185)2.10311587
102Choanal stenosis (HP:0000452)2.06985878
103Agitation (HP:0000713)2.05060882
104Postural instability (HP:0002172)2.04494771
105Median cleft lip (HP:0000161)2.04138231
106Hemiplegia (HP:0002301)2.03524270
107Drooling (HP:0002307)2.03352498
108Dysdiadochokinesis (HP:0002075)2.01848120
109Pancreatic cysts (HP:0001737)2.00011739
110Hyperventilation (HP:0002883)1.99653268
111Chronic hepatic failure (HP:0100626)1.99140144
112Papilledema (HP:0001085)1.96810689
113Shawl scrotum (HP:0000049)1.96546520
114Prolonged QT interval (HP:0001657)1.95769722
115Nephrogenic diabetes insipidus (HP:0009806)1.94562443
116Bifid uvula (HP:0000193)1.94435482
117Ulnar bowing (HP:0003031)1.92056786
118Medial flaring of the eyebrow (HP:0010747)1.91260838
119Patellar aplasia (HP:0006443)1.90846022
120Chronic bronchitis (HP:0004469)1.90544177
121Increased number of teeth (HP:0011069)1.90246783
122Choroideremia (HP:0001139)1.89699221
123Large for gestational age (HP:0001520)1.89030956
124Excessive salivation (HP:0003781)1.87571926
125Aplasia of the musculature (HP:0100854)1.87493421
126Pustule (HP:0200039)1.87079942
127Diminished movement (HP:0002374)1.87015547
128Aplasia involving bones of the upper limbs (HP:0009823)1.86439668
129Aplasia of the phalanges of the hand (HP:0009802)1.86439668
130Aplasia involving bones of the extremities (HP:0009825)1.86439668
131Bronchiectasis (HP:0002110)1.85643841
132Small hand (HP:0200055)1.85592880
133Tented upper lip vermilion (HP:0010804)1.85346297
134Abnormality of male internal genitalia (HP:0000022)1.85191217
135Impaired vibration sensation in the lower limbs (HP:0002166)1.84922528
136Growth hormone excess (HP:0000845)1.82429018
137Polydipsia (HP:0001959)1.82279060
138Abnormal drinking behavior (HP:0030082)1.82279060
139Vertebral hypoplasia (HP:0008417)1.80550723
140Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.80550723
141Hypotelorism (HP:0000601)1.80501916
142Optic nerve hypoplasia (HP:0000609)1.80462076
143Abnormal number of incisors (HP:0011064)1.79561787
144Hypokinesia (HP:0002375)1.78215707
145Obstructive sleep apnea (HP:0002870)1.77872538
146Anophthalmia (HP:0000528)1.77799239
147Heterotopia (HP:0002282)1.77123970
148Glioma (HP:0009733)1.76931612
149Absent speech (HP:0001344)1.76681159
150Focal dystonia (HP:0004373)1.76646268
151Neoplasm of the oral cavity (HP:0100649)1.76181126
152Cutaneous finger syndactyly (HP:0010554)1.75915675
153Ectopic anus (HP:0004397)1.75419502
154Left ventricular hypertrophy (HP:0001712)1.74902437
155Status epilepticus (HP:0002133)1.74717849
156Abnormality of the ileum (HP:0001549)1.73365316
157Atelectasis (HP:0100750)1.73214970
158Broad-based gait (HP:0002136)1.73060758
159Ankle clonus (HP:0011448)1.72478901
160Epileptiform EEG discharges (HP:0011182)1.71973022
161Aplasia/Hypoplasia of the patella (HP:0006498)1.70404876
162Aqueductal stenosis (HP:0002410)1.70389018
163Infertility (HP:0000789)1.70310502
164Aplasia/Hypoplasia of the spleen (HP:0010451)1.69927769
165Postaxial hand polydactyly (HP:0001162)1.68667051
166Anomalous pulmonary venous return (HP:0010772)1.67973030
167Abnormality of the 4th metacarpal (HP:0010012)1.67936982
168Oligodactyly (hands) (HP:0001180)1.67397242
169Tubular atrophy (HP:0000092)1.66721913
170Partial duplication of thumb phalanx (HP:0009944)1.66520752
171Cutaneous syndactyly (HP:0012725)1.65514672
172Morphological abnormality of the pyramidal tract (HP:0002062)1.64796791
173Degeneration of the lateral corticospinal tracts (HP:0002314)1.64769851
174Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.64769851
175Abnormal EKG (HP:0003115)1.63785525

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK4.75220558
2TYRO34.43045368
3DDR23.94626587
4MAPK153.41443435
5MAP3K63.19381664
6UHMK13.07457464
7NTRK22.70603172
8PINK12.56790660
9FGR2.48759442
10MAP3K112.37104137
11PDGFRA2.35405668
12MAP3K92.33801522
13MARK12.30471966
14DAPK12.29575351
15EPHB22.14142341
16MATK2.08486108
17YES11.97337854
18CAMKK11.92576902
19FGFR21.87337214
20AKT31.84179300
21MARK21.71009866
22PRPF4B1.64453471
23NTRK31.64274065
24SGK2231.57537349
25SGK4941.57537349
26PRKD21.55524562
27SIK31.54292655
28PHKG21.48258359
29PHKG11.48258359
30LATS21.45095279
31CAMK11.40751085
32PAK31.36547000
33STK111.36178158
34EPHA41.35122140
35MINK11.32728126
36MAP3K41.23437882
37SIK21.22634413
38PKN11.20582651
39BMX1.17665944
40CDC42BPA1.17298259
41PRKCH1.11642909
42SGK21.10154284
43MAP3K101.08346841
44MAP2K41.06675663
45DYRK1B1.05814530
46CAMK2B1.04015222
47CSK0.99193918
48CAMKK20.94461195
49RPS6KC10.90055073
50RPS6KL10.90055073
51EPHA30.87174209
52CAMK2A0.85866268
53CAMK1G0.85378986
54CDK70.84856021
55MAPK130.83597513
56DYRK20.81738311
57CAMK40.81330931
58PIM20.79747249
59CASK0.77384077
60MAP3K70.76302618
61PAK60.76115290
62PNCK0.76091264
63RPS6KA20.74685216
64MAPK120.74471407
65CDK50.73698631
66RIPK10.73626421
67GRK70.73589631
68ERBB30.73290974
69CHEK20.73211042
70ERBB20.73125017
71RPS6KA60.72551019
72GRK50.71875820
73SGK30.70873735
74GSK3A0.70617573
75PLK20.70562450
76WNK30.70193453
77WNK40.68974176
78CAMK2G0.68809477
79DMPK0.67328299
80CSNK1G10.64553986
81TAOK20.64449941
82TNIK0.63892376
83CAMK1D0.63229058
84CDK180.62033848
85DYRK1A0.59525187
86CDK150.56844717
87ALK0.54425384
88MAP2K70.53637055
89KSR10.52669923
90FGFR40.52230597
91TIE10.52086762
92BMPR1B0.51796327
93PDGFRB0.51642353
94PRKD30.51640098
95WNK10.51069840
96CDK11A0.50748462
97RAF10.50452474
98FGFR10.48811083
99CAMK2D0.48807293
100PRKACA0.48425286
101RPS6KA10.48357967
102MAPK100.48328908
103DAPK20.48102978
104PLK10.46931641
105SGK10.46730683
106DAPK30.46411056
107CDK140.46381507
108STK380.46331568
109PRKCE0.45837824
110RPS6KB10.45700037
111CDK60.45687027
112INSRR0.43827983
113ROCK10.43239577
114PRKG10.42161231
115BCR0.42135474
116SRPK10.41937258
117AURKA0.41901818
118CDK190.41193832
119TNK20.40958599
120PRKAA10.39666514
121ROCK20.38862533
122PDK40.38455301
123PDK30.38455301
124FES0.38170325
125CDK20.38109495
126TRPM70.36772749
127RPS6KA30.35444155
128MAPK80.34574753
129FYN0.34482628
130GRK10.34155415
131MTOR0.34125496
132CSNK1G30.34103690
133EGFR0.33617532
134PRKCG0.33346255
135PRKCA0.33243398
136CSNK1G20.32936151
137NME10.32424783
138PRKCZ0.32420996
139MAP3K120.31965194
140MAPK40.31895401
141GSK3B0.31705628
142OXSR10.31067354
143PRKD10.30767129
144ARAF0.30048657
145NTRK10.29596531
146CSNK1D0.29573392
147HIPK20.29444571

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000613.59859184
2Nicotine addiction_Homo sapiens_hsa050333.24941458
3Mismatch repair_Homo sapiens_hsa034302.73406646
4Synaptic vesicle cycle_Homo sapiens_hsa047212.27596573
5Base excision repair_Homo sapiens_hsa034102.23546062
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.21193565
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.09191158
8Circadian rhythm_Homo sapiens_hsa047102.05989028
9GABAergic synapse_Homo sapiens_hsa047272.01724395
10mRNA surveillance pathway_Homo sapiens_hsa030151.90596267
11Olfactory transduction_Homo sapiens_hsa047401.89265004
12Amphetamine addiction_Homo sapiens_hsa050311.82840528
13Hedgehog signaling pathway_Homo sapiens_hsa043401.67964432
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.65732030
15Dopaminergic synapse_Homo sapiens_hsa047281.64687655
16Oocyte meiosis_Homo sapiens_hsa041141.64301504
17Morphine addiction_Homo sapiens_hsa050321.61258139
18Glutamatergic synapse_Homo sapiens_hsa047241.58177670
19mTOR signaling pathway_Homo sapiens_hsa041501.56829372
20Hippo signaling pathway_Homo sapiens_hsa043901.55209653
21Long-term potentiation_Homo sapiens_hsa047201.53787986
22Gap junction_Homo sapiens_hsa045401.51312593
23Spliceosome_Homo sapiens_hsa030401.50517231
24Long-term depression_Homo sapiens_hsa047301.47211260
25Circadian entrainment_Homo sapiens_hsa047131.45886401
26Wnt signaling pathway_Homo sapiens_hsa043101.43820278
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.42766611
28DNA replication_Homo sapiens_hsa030301.40324139
29ErbB signaling pathway_Homo sapiens_hsa040121.36379249
30Fanconi anemia pathway_Homo sapiens_hsa034601.36193497
31Serotonergic synapse_Homo sapiens_hsa047261.32990611
32Taste transduction_Homo sapiens_hsa047421.32278500
33RNA transport_Homo sapiens_hsa030131.30567904
34Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.26591902
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.25929666
36Nucleotide excision repair_Homo sapiens_hsa034201.21222919
37Insulin secretion_Homo sapiens_hsa049111.18352751
38Axon guidance_Homo sapiens_hsa043601.17583004
39Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.16937003
40Dilated cardiomyopathy_Homo sapiens_hsa054141.15033227
41Longevity regulating pathway - mammal_Homo sapiens_hsa042111.09240658
42Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08315787
43VEGF signaling pathway_Homo sapiens_hsa043701.06891661
44Salivary secretion_Homo sapiens_hsa049701.05742656
45Cocaine addiction_Homo sapiens_hsa050301.05509094
46GnRH signaling pathway_Homo sapiens_hsa049121.05461642
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.04891881
48Basal cell carcinoma_Homo sapiens_hsa052171.01342010
49Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.01301410
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00813233
51Colorectal cancer_Homo sapiens_hsa052101.00712092
52Choline metabolism in cancer_Homo sapiens_hsa052310.99845875
53Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99202498
54Notch signaling pathway_Homo sapiens_hsa043300.94933726
55Carbohydrate digestion and absorption_Homo sapiens_hsa049730.94545714
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.94154204
57Phospholipase D signaling pathway_Homo sapiens_hsa040720.93798651
58Oxytocin signaling pathway_Homo sapiens_hsa049210.93237076
59Estrogen signaling pathway_Homo sapiens_hsa049150.91852176
60Cholinergic synapse_Homo sapiens_hsa047250.91329036
61Calcium signaling pathway_Homo sapiens_hsa040200.91085953
62Vascular smooth muscle contraction_Homo sapiens_hsa042700.88921585
63Dorso-ventral axis formation_Homo sapiens_hsa043200.87477477
64MAPK signaling pathway_Homo sapiens_hsa040100.86449377
65Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.84584909
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84374110
67Aldosterone synthesis and secretion_Homo sapiens_hsa049250.83265850
68Renin secretion_Homo sapiens_hsa049240.82946986
69Phototransduction_Homo sapiens_hsa047440.82671591
70Cardiac muscle contraction_Homo sapiens_hsa042600.79499187
71Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.79123500
72Histidine metabolism_Homo sapiens_hsa003400.79029655
73Bile secretion_Homo sapiens_hsa049760.78961175
74Pancreatic secretion_Homo sapiens_hsa049720.77899277
75Ovarian steroidogenesis_Homo sapiens_hsa049130.77860914
76Melanogenesis_Homo sapiens_hsa049160.77036932
77Adherens junction_Homo sapiens_hsa045200.76189377
78Thyroid hormone synthesis_Homo sapiens_hsa049180.75943749
79Linoleic acid metabolism_Homo sapiens_hsa005910.75550723
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.73777363
81TGF-beta signaling pathway_Homo sapiens_hsa043500.73267118
82alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.72944935
83Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.72884870
84Type II diabetes mellitus_Homo sapiens_hsa049300.72733047
85Gastric acid secretion_Homo sapiens_hsa049710.70083487
86Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.69199533
87Collecting duct acid secretion_Homo sapiens_hsa049660.69140480
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68896432
89Glioma_Homo sapiens_hsa052140.67763553
90Tight junction_Homo sapiens_hsa045300.65862959
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64463524
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.64437193
93Regulation of autophagy_Homo sapiens_hsa041400.64326307
94Ether lipid metabolism_Homo sapiens_hsa005650.63414852
95Vibrio cholerae infection_Homo sapiens_hsa051100.63151972
96Alcoholism_Homo sapiens_hsa050340.63097966
97Oxidative phosphorylation_Homo sapiens_hsa001900.62344369
98beta-Alanine metabolism_Homo sapiens_hsa004100.61754455
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61326576
100Arginine and proline metabolism_Homo sapiens_hsa003300.60920734
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60073525
102Endometrial cancer_Homo sapiens_hsa052130.58220756
1032-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58086001
104Homologous recombination_Homo sapiens_hsa034400.57359226
105Alzheimers disease_Homo sapiens_hsa050100.56279933
106cAMP signaling pathway_Homo sapiens_hsa040240.56145623
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.55917549
108Bladder cancer_Homo sapiens_hsa052190.55601991
109Cell cycle_Homo sapiens_hsa041100.55369114
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54144212
111Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53261039
112Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52140639
113Parkinsons disease_Homo sapiens_hsa050120.51853328
114Glucagon signaling pathway_Homo sapiens_hsa049220.51672150
115Neurotrophin signaling pathway_Homo sapiens_hsa047220.51262462
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.50757374
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50390477
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47610557
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47284345
120Ras signaling pathway_Homo sapiens_hsa040140.47152684
121Insulin signaling pathway_Homo sapiens_hsa049100.46921274
122Biosynthesis of amino acids_Homo sapiens_hsa012300.45068792
123Inositol phosphate metabolism_Homo sapiens_hsa005620.44564477
124AMPK signaling pathway_Homo sapiens_hsa041520.44324559
125Huntingtons disease_Homo sapiens_hsa050160.44229309
126RNA polymerase_Homo sapiens_hsa030200.42961683
127Rap1 signaling pathway_Homo sapiens_hsa040150.42690483
128Butanoate metabolism_Homo sapiens_hsa006500.42686736
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.40646983
130p53 signaling pathway_Homo sapiens_hsa041150.40509803
131Endocytosis_Homo sapiens_hsa041440.39990206
132Shigellosis_Homo sapiens_hsa051310.38602879
133Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37990599
134Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37635605

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