ZSCAN26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.17105663
2nucleobase catabolic process (GO:0046113)4.91964155
3protein polyglutamylation (GO:0018095)4.57827791
4DNA damage response, detection of DNA damage (GO:0042769)4.29728215
5negative regulation of dendrite morphogenesis (GO:0050774)4.19064209
6inositol phosphate catabolic process (GO:0071545)4.16044379
7neural tube formation (GO:0001841)4.13736205
8negative regulation of synaptic transmission, GABAergic (GO:0032229)4.06226016
9DNA integration (GO:0015074)4.00925714
10neurotransmitter-gated ion channel clustering (GO:0072578)3.93436142
11nonmotile primary cilium assembly (GO:0035058)3.93251386
12synaptic vesicle docking involved in exocytosis (GO:0016081)3.89173941
13protein localization to cilium (GO:0061512)3.88305107
14establishment of mitochondrion localization (GO:0051654)3.88196294
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.81379501
16presynaptic membrane assembly (GO:0097105)3.70814663
17startle response (GO:0001964)3.66947277
18pyrimidine dimer repair (GO:0006290)3.66055484
19neuron cell-cell adhesion (GO:0007158)3.62932857
20limb bud formation (GO:0060174)3.52295465
21DNA double-strand break processing (GO:0000729)3.50174403
22cell differentiation involved in metanephros development (GO:0072202)3.49479792
23response to pheromone (GO:0019236)3.49276244
24protein-cofactor linkage (GO:0018065)3.44637665
25phosphorylated carbohydrate dephosphorylation (GO:0046838)3.43222695
26inositol phosphate dephosphorylation (GO:0046855)3.43222695
27signal peptide processing (GO:0006465)3.40051497
28epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.37954501
29retinal ganglion cell axon guidance (GO:0031290)3.36285001
30histone H2A acetylation (GO:0043968)3.31568220
31regulation of feeding behavior (GO:0060259)3.31400817
32head development (GO:0060322)3.28078697
33cilium morphogenesis (GO:0060271)3.25027766
34axoneme assembly (GO:0035082)3.24239229
35regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.24165715
36regulation of cilium movement (GO:0003352)3.18907725
37presynaptic membrane organization (GO:0097090)3.15820450
38membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.14478548
39neuron recognition (GO:0008038)3.14384195
40axonal fasciculation (GO:0007413)3.11533827
41regulation of penile erection (GO:0060405)3.10861215
42positive regulation of mitochondrial fission (GO:0090141)3.10708208
43regulation of development, heterochronic (GO:0040034)3.08783491
44olfactory bulb development (GO:0021772)3.08313020
45cullin deneddylation (GO:0010388)3.06330080
46negative regulation of dendrite development (GO:2000171)3.04846618
47behavioral response to nicotine (GO:0035095)3.01585536
48mitochondrion distribution (GO:0048311)3.00963830
49C4-dicarboxylate transport (GO:0015740)3.00823304
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.00196530
51regulation of rhodopsin mediated signaling pathway (GO:0022400)2.99464678
52glycosphingolipid biosynthetic process (GO:0006688)2.94988950
53protein deneddylation (GO:0000338)2.93606573
54hippocampus development (GO:0021766)2.93456998
55iron-sulfur cluster assembly (GO:0016226)2.93109103
56metallo-sulfur cluster assembly (GO:0031163)2.93109103
57regulation of mitotic spindle checkpoint (GO:1903504)2.93042078
58regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.93042078
59synaptic transmission, glutamatergic (GO:0035249)2.92038369
60rhodopsin mediated signaling pathway (GO:0016056)2.91798225
61female mating behavior (GO:0060180)2.91709990
62negative regulation of transcription regulatory region DNA binding (GO:2000678)2.90984438
63somite development (GO:0061053)2.90465258
64postsynaptic membrane organization (GO:0001941)2.88642768
65regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.88608868
66relaxation of smooth muscle (GO:0044557)2.87972663
67regulation of synaptic transmission, GABAergic (GO:0032228)2.87869536
68regulation of synaptic vesicle transport (GO:1902803)2.86131377
69negative regulation of glycogen metabolic process (GO:0070874)2.86048987
70regulation of synaptic vesicle exocytosis (GO:2000300)2.84349355
71synapse assembly (GO:0007416)2.83170682
72resolution of meiotic recombination intermediates (GO:0000712)2.81193380
73positive regulation of cellular amide metabolic process (GO:0034250)2.81055865
74ganglion development (GO:0061548)2.80199603
75cell migration in hindbrain (GO:0021535)2.79972794
76cilium organization (GO:0044782)2.77954684
77chaperone-mediated protein transport (GO:0072321)2.76329005
78negative regulation of telomere maintenance (GO:0032205)2.75356899
79neuronal action potential propagation (GO:0019227)2.75146585
80neuron-neuron synaptic transmission (GO:0007270)2.75040530
81ER overload response (GO:0006983)2.74617851
82regulation of telomere maintenance (GO:0032204)2.71724770
83eye photoreceptor cell development (GO:0042462)2.71375916
84cilium assembly (GO:0042384)2.71007589
85photoreceptor cell development (GO:0042461)2.70377796
86positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.69600612
87mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.69600612
88establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.69276714
89mitochondrion transport along microtubule (GO:0047497)2.69276714
90long-term synaptic potentiation (GO:0060291)2.69195099
91calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.68964573
92neurotransmitter secretion (GO:0007269)2.68813050
93sleep (GO:0030431)2.68370315
94regulation of glucokinase activity (GO:0033131)2.67700668
95regulation of hexokinase activity (GO:1903299)2.67700668
96regulation of female receptivity (GO:0045924)2.66388721
97epithelial cilium movement (GO:0003351)2.65741117
98synaptic vesicle exocytosis (GO:0016079)2.64503492
99glutamate secretion (GO:0014047)2.62742700
100negative regulation of glycogen biosynthetic process (GO:0045719)2.62490291
101negative regulation of DNA recombination (GO:0045910)2.62269349
102adenosine metabolic process (GO:0046085)2.60821153
103sympathetic nervous system development (GO:0048485)2.58745182
104forebrain neuron differentiation (GO:0021879)2.56444643
105synaptic vesicle endocytosis (GO:0048488)2.56111408
106oxaloacetate metabolic process (GO:0006107)2.55551002
107retinal cone cell development (GO:0046549)2.55299603
108gamma-aminobutyric acid transport (GO:0015812)2.55227994
109prostate gland growth (GO:0060736)2.54858689
110water-soluble vitamin biosynthetic process (GO:0042364)2.54696856
111retinal rod cell development (GO:0046548)2.54233822
112regulation of short-term neuronal synaptic plasticity (GO:0048172)2.54098552
113nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.53814619
114cytochrome complex assembly (GO:0017004)2.51710673
115RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.51347640
116negative regulation of axon guidance (GO:1902668)2.51146171
117protein K48-linked ubiquitination (GO:0070936)2.47839622
118succinate metabolic process (GO:0006105)2.45671716
119positive regulation of oligodendrocyte differentiation (GO:0048714)2.45444997
120negative regulation of neurotransmitter secretion (GO:0046929)2.44920782
121viral protein processing (GO:0019082)2.44846969
122GPI anchor metabolic process (GO:0006505)2.44405640
123mechanosensory behavior (GO:0007638)2.44359729
124cyclic nucleotide catabolic process (GO:0009214)2.44340739
125exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.43807122
126intraciliary transport (GO:0042073)2.43703277
127transferrin transport (GO:0033572)2.42699713
128glial cell proliferation (GO:0014009)2.42037996
129cAMP catabolic process (GO:0006198)2.41844075
130protein complex biogenesis (GO:0070271)2.41478347
131cell differentiation in spinal cord (GO:0021515)2.41446192
132spinal cord association neuron differentiation (GO:0021527)2.41392431
133cerebellar Purkinje cell differentiation (GO:0021702)2.40704134
134protein K11-linked deubiquitination (GO:0035871)2.39742536
135positive regulation of amino acid transport (GO:0051957)2.39729748
136ionotropic glutamate receptor signaling pathway (GO:0035235)2.39078102
137regulation of amino acid transport (GO:0051955)2.39069632
138regulation of timing of cell differentiation (GO:0048505)2.39055142
139positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.38256887
140histone H2A ubiquitination (GO:0033522)2.37947566
141RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.37371707
142tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.37371707
143auditory receptor cell stereocilium organization (GO:0060088)2.37370933
144pH reduction (GO:0045851)2.37321348
145regulation of action potential (GO:0098900)2.36550705
146retina layer formation (GO:0010842)2.36384142
147dendritic spine morphogenesis (GO:0060997)2.36256808
148rRNA catabolic process (GO:0016075)2.35455103
149brain morphogenesis (GO:0048854)2.35287915
150smoothened signaling pathway (GO:0007224)2.35095653
151appendage development (GO:0048736)2.34927115
152limb development (GO:0060173)2.34927115
153positive regulation of muscle hypertrophy (GO:0014742)2.34395448
154positive regulation of cardiac muscle hypertrophy (GO:0010613)2.34395448
155positive regulation of protein sumoylation (GO:0033235)2.33512684
156regulation of glutamate receptor signaling pathway (GO:1900449)2.33414914
157intracellular pH reduction (GO:0051452)2.33177280
158trivalent inorganic cation transport (GO:0072512)2.32333630
159ferric iron transport (GO:0015682)2.32333630
160regulation of neurotransmitter secretion (GO:0046928)2.30061906
161negative regulation of mast cell activation (GO:0033004)2.29023842
162nucleotide transmembrane transport (GO:1901679)2.28789494
163regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.27895949
164regulation of mitochondrial fission (GO:0090140)2.26812097
165omega-hydroxylase P450 pathway (GO:0097267)2.26428303
166NADH metabolic process (GO:0006734)2.23977007
167regulation of beta-amyloid formation (GO:1902003)2.23406756
168striatum development (GO:0021756)2.22875687
169regulation of relaxation of muscle (GO:1901077)2.22326042
170lactate metabolic process (GO:0006089)2.21116200
171cell differentiation involved in kidney development (GO:0061005)2.20891279
172urinary tract smooth muscle contraction (GO:0014848)2.20687903
173negative regulation of catecholamine secretion (GO:0033604)2.20204911
174heart process (GO:0003015)2.18949484
175heart contraction (GO:0060047)2.18949484
176androgen biosynthetic process (GO:0006702)2.18501542
177negative regulation of cation channel activity (GO:2001258)2.18126404
178photoreceptor cell maintenance (GO:0045494)2.17805313
179polyol catabolic process (GO:0046174)2.17583379
180mannosylation (GO:0097502)2.17256076
181vocalization behavior (GO:0071625)2.15840420
182protein localization to synapse (GO:0035418)2.15380101
183respiratory chain complex IV assembly (GO:0008535)2.14252042
184cardiac conduction (GO:0061337)2.13826520
185oligosaccharide biosynthetic process (GO:0009312)2.13145061

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.96647387
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.02969328
3ZNF274_21170338_ChIP-Seq_K562_Hela3.81164574
4IGF1R_20145208_ChIP-Seq_DFB_Human3.11797212
5NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.84467740
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.75950929
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.61661818
8TAF15_26573619_Chip-Seq_HEK293_Human2.59655458
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.56596662
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.47168953
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.45358183
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.36761457
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.26398752
14EZH2_22144423_ChIP-Seq_EOC_Human2.21049960
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.11298547
16P300_19829295_ChIP-Seq_ESCs_Human2.10047736
17FLI1_27457419_Chip-Seq_LIVER_Mouse2.09104330
18SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.06863237
19SMAD4_21799915_ChIP-Seq_A2780_Human2.02813146
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.02299923
21SMAD_19615063_ChIP-ChIP_OVARY_Human2.00908147
22RBPJ_22232070_ChIP-Seq_NCS_Mouse1.92181761
23SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.90979913
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88637400
25SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.86063318
26CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.85762844
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.85705744
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.79866959
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75027835
30AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.69067553
31PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.68575898
32SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.64265658
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.63047190
34STAT3_23295773_ChIP-Seq_U87_Human1.58071332
35CBP_20019798_ChIP-Seq_JUKART_Human1.56870792
36IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.56870792
37SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.56857820
38POU5F1_16153702_ChIP-ChIP_HESCs_Human1.56508370
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.56182443
40PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55972834
41SUZ12_27294783_Chip-Seq_NPCs_Mouse1.55082458
42MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.54467295
43FUS_26573619_Chip-Seq_HEK293_Human1.54393503
44NANOG_18555785_Chip-Seq_ESCs_Mouse1.54178142
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.54010538
46EED_16625203_ChIP-ChIP_MESCs_Mouse1.53905233
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53873364
48OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53179050
49VDR_23849224_ChIP-Seq_CD4+_Human1.53075929
50E2F1_18555785_Chip-Seq_ESCs_Mouse1.51299856
51EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.49216721
52TCF4_23295773_ChIP-Seq_U87_Human1.48944419
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.47227930
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.46810519
55SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46475948
56NFE2_27457419_Chip-Seq_LIVER_Mouse1.45971930
57P53_22387025_ChIP-Seq_ESCs_Mouse1.45938391
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44755025
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44539036
60EZH2_27294783_Chip-Seq_NPCs_Mouse1.43479831
61AR_25329375_ChIP-Seq_VCAP_Human1.42118249
62VDR_22108803_ChIP-Seq_LS180_Human1.41539067
63ELK1_19687146_ChIP-ChIP_HELA_Human1.41344405
64SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40812375
65STAT3_18555785_Chip-Seq_ESCs_Mouse1.40749118
66TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39117984
67SUZ12_18555785_Chip-Seq_ESCs_Mouse1.36587905
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.35970142
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.35836539
70NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.34719194
71RUNX1_27457419_Chip-Seq_LIVER_Mouse1.33670045
72ZNF217_24962896_ChIP-Seq_MCF-7_Human1.33526122
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.33416509
74JARID2_20064375_ChIP-Seq_MESCs_Mouse1.32646800
75GATA1_22025678_ChIP-Seq_K562_Human1.32336231
76AHR_22903824_ChIP-Seq_MCF-7_Human1.31496094
77P300_18555785_Chip-Seq_ESCs_Mouse1.31450186
78NMYC_18555785_Chip-Seq_ESCs_Mouse1.31378642
79CMYC_18555785_Chip-Seq_ESCs_Mouse1.29907322
80GATA2_21666600_ChIP-Seq_HMVEC_Human1.29668781
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29119244
82GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28969320
83JARID2_20075857_ChIP-Seq_MESCs_Mouse1.28670869
84EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.28365827
85EZH2_18974828_ChIP-Seq_MESCs_Mouse1.27822278
86RNF2_18974828_ChIP-Seq_MESCs_Mouse1.27822278
87EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.27694636
88SOX2_18555785_Chip-Seq_ESCs_Mouse1.26542401
89REST_18959480_ChIP-ChIP_MESCs_Mouse1.26299976
90ETS1_20019798_ChIP-Seq_JURKAT_Human1.26047456
91ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.24981878
92EZH2_27304074_Chip-Seq_ESCs_Mouse1.24834875
93ER_23166858_ChIP-Seq_MCF-7_Human1.23551340
94NRF2_20460467_ChIP-Seq_MEFs_Mouse1.22989572
95NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.22989572
96SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.22956704
97REST_21632747_ChIP-Seq_MESCs_Mouse1.22815509
98PADI4_21655091_ChIP-ChIP_MCF-7_Human1.22717952
99PU1_27457419_Chip-Seq_LIVER_Mouse1.22164853
100BCAT_22108803_ChIP-Seq_LS180_Human1.21123525
101IRF1_19129219_ChIP-ChIP_H3396_Human1.20931505
102TP53_22573176_ChIP-Seq_HFKS_Human1.20289276
103KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.20129001
104RNF2_27304074_Chip-Seq_NSC_Mouse1.19575703
105RUNX2_22187159_ChIP-Seq_PCA_Human1.19380127
106TAL1_26923725_Chip-Seq_HPCs_Mouse1.18485117
107CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18478371
108CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17569237
109MTF2_20144788_ChIP-Seq_MESCs_Mouse1.16717277
110BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.14712937
111MYC_18940864_ChIP-ChIP_HL60_Human1.13986596
112DROSHA_22980978_ChIP-Seq_HELA_Human1.13970035
113VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.13352331
114EWS_26573619_Chip-Seq_HEK293_Human1.13066234
115NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12968076
116FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12904407
117ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.11534964
118TCF4_22108803_ChIP-Seq_LS180_Human1.11531899
119SOX2_21211035_ChIP-Seq_LN229_Gbm1.11136632
120SOX2_16153702_ChIP-ChIP_HESCs_Human1.09792887
121* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.08981079
122OCT4_18555785_Chip-Seq_ESCs_Mouse1.08917269
123AR_21572438_ChIP-Seq_LNCaP_Human1.08658625
124PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.08453677
125PRDM14_20953172_ChIP-Seq_ESCs_Human1.07655283
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.07586477
127SRF_21415370_ChIP-Seq_HL-1_Mouse1.07576905
128SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06748544
129FLI1_21867929_ChIP-Seq_TH2_Mouse1.06121286
130HTT_18923047_ChIP-ChIP_STHdh_Human1.06094682
131PCGF2_27294783_Chip-Seq_NPCs_Mouse1.05871507
132KDM2B_26808549_Chip-Seq_REH_Human1.04909389
133RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.04358114
134KLF4_18555785_Chip-Seq_ESCs_Mouse1.04049055
135CRX_20693478_ChIP-Seq_RETINA_Mouse1.03154207
136TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.02509807
137ELF1_17652178_ChIP-ChIP_JURKAT_Human1.02191536
138TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02071881
139JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.02029349
140NANOG_19829295_ChIP-Seq_ESCs_Human1.01429292
141SOX2_19829295_ChIP-Seq_ESCs_Human1.01429292
142CREB1_15753290_ChIP-ChIP_HEK293T_Human1.01379007
143YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96519460
144NOTCH1_21737748_ChIP-Seq_TLL_Human0.93959258
145CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.93322311
146TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91918793
147TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91757869
148POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91757869
149THAP11_20581084_ChIP-Seq_MESCs_Mouse0.91129007

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005646_abnormal_pituitary_gland4.42651247
2MP0003787_abnormal_imprinting3.90880812
3MP0002102_abnormal_ear_morphology3.52936022
4MP0002876_abnormal_thyroid_physiology3.11599875
5MP0001188_hyperpigmentation3.02413118
6MP0009780_abnormal_chondrocyte_physiolo3.00556731
7MP0009697_abnormal_copulation2.61911127
8MP0008789_abnormal_olfactory_epithelium2.52053056
9MP0003122_maternal_imprinting2.43547922
10MP0003880_abnormal_central_pattern2.42788210
11MP0000778_abnormal_nervous_system2.35719107
12MP0005499_abnormal_olfactory_system2.35064729
13MP0005394_taste/olfaction_phenotype2.35064729
14MP0003183_abnormal_peptide_metabolism2.29057933
15MP0009046_muscle_twitch2.27568668
16MP0005645_abnormal_hypothalamus_physiol2.25080669
17MP0001529_abnormal_vocalization2.22670962
18MP0001986_abnormal_taste_sensitivity2.20755318
19MP0009745_abnormal_behavioral_response2.18034916
20MP0010386_abnormal_urinary_bladder2.15186106
21MP0002822_catalepsy2.09087244
22MP0005171_absent_coat_pigmentation2.02493756
23MP0008058_abnormal_DNA_repair2.01203365
24MP0005551_abnormal_eye_electrophysiolog1.91027559
25MP0002638_abnormal_pupillary_reflex1.89040677
26MP0002272_abnormal_nervous_system1.86217545
27MP0006072_abnormal_retinal_apoptosis1.81756922
28MP0002736_abnormal_nociception_after1.80023867
29MP0002064_seizures1.78885131
30MP0003635_abnormal_synaptic_transmissio1.76821576
31MP0005409_darkened_coat_color1.75420038
32MP0002572_abnormal_emotion/affect_behav1.63970212
33MP0002735_abnormal_chemical_nociception1.63264333
34MP0002009_preneoplasia1.61148280
35MP0004859_abnormal_synaptic_plasticity1.61015324
36MP0000015_abnormal_ear_pigmentation1.60686226
37MP0004147_increased_porphyrin_level1.60641066
38MP0002063_abnormal_learning/memory/cond1.60049911
39MP0005084_abnormal_gallbladder_morpholo1.58827341
40MP0003195_calcinosis1.58167321
41MP0001968_abnormal_touch/_nociception1.57950584
42MP0005423_abnormal_somatic_nervous1.56243742
43MP0002751_abnormal_autonomic_nervous1.54858090
44MP0001502_abnormal_circadian_rhythm1.53328181
45MP0000955_abnormal_spinal_cord1.52622798
46MP0000013_abnormal_adipose_tissue1.51370699
47MP0001177_atelectasis1.51113993
48MP0001764_abnormal_homeostasis1.45514272
49MP0000569_abnormal_digit_pigmentation1.45269301
50MP0005085_abnormal_gallbladder_physiolo1.44417325
51MP0000516_abnormal_urinary_system1.44150600
52MP0005367_renal/urinary_system_phenotyp1.44150600
53MP0002877_abnormal_melanocyte_morpholog1.44014122
54MP0001984_abnormal_olfaction1.43903160
55MP0004782_abnormal_surfactant_physiolog1.43457000
56MP0001501_abnormal_sleep_pattern1.41945332
57MP0005379_endocrine/exocrine_gland_phen1.41885024
58MP0000678_abnormal_parathyroid_gland1.39692828
59MP0002734_abnormal_mechanical_nocicepti1.38496304
60MP0006292_abnormal_olfactory_placode1.36055373
61MP0004811_abnormal_neuron_physiology1.35947609
62MP0003943_abnormal_hepatobiliary_system1.35740059
63MP0003890_abnormal_embryonic-extraembry1.35379778
64MP0008877_abnormal_DNA_methylation1.31093058
65MP0003252_abnormal_bile_duct1.29902044
66MP0002067_abnormal_sensory_capabilities1.28875191
67MP0003121_genomic_imprinting1.28637815
68MP0008569_lethality_at_weaning1.28234546
69MP0000681_abnormal_thyroid_gland1.27074870
70MP0002882_abnormal_neuron_morphology1.26749941
71MP0005365_abnormal_bile_salt1.26617779
72MP0004133_heterotaxia1.25628866
73MP0000049_abnormal_middle_ear1.24816934
74MP0008995_early_reproductive_senescence1.24803009
75MP0004142_abnormal_muscle_tone1.24200294
76MP0002184_abnormal_innervation1.22762483
77MP0001486_abnormal_startle_reflex1.21388528
78MP0001293_anophthalmia1.21349689
79MP0002752_abnormal_somatic_nervous1.18280442
80MP0002234_abnormal_pharynx_morphology1.18038949
81MP0003879_abnormal_hair_cell1.17422186
82MP0004043_abnormal_pH_regulation1.16029256
83MP0002139_abnormal_hepatobiliary_system1.15842529
84MP0002938_white_spotting1.13637297
85MP0004270_analgesia1.12188250
86MP0005075_abnormal_melanosome_morpholog1.11916042
87MP0005253_abnormal_eye_physiology1.09958863
88MP0002653_abnormal_ependyma_morphology1.09372659
89MP0008875_abnormal_xenobiotic_pharmacok1.08309846
90MP0005670_abnormal_white_adipose1.05904147
91MP0005187_abnormal_penis_morphology1.04577407
92MP0002557_abnormal_social/conspecific_i1.03175226
93MP0005195_abnormal_posterior_eye1.02307852
94MP0001879_abnormal_lymphatic_vessel1.01377396
95MP0000566_synostosis1.00283900
96MP0004924_abnormal_behavior0.99785010
97MP0005386_behavior/neurological_phenoty0.99785010
98MP0002233_abnormal_nose_morphology0.99170141
99MP0005503_abnormal_tendon_morphology0.98515448
100MP0006276_abnormal_autonomic_nervous0.97338282
101MP0002909_abnormal_adrenal_gland0.96864211
102MP0003718_maternal_effect0.94642276
103MP0002152_abnormal_brain_morphology0.94434144
104MP0002229_neurodegeneration0.94408781
105MP0002733_abnormal_thermal_nociception0.94093786
106MP0004885_abnormal_endolymph0.93799989
107MP0002928_abnormal_bile_duct0.93358936
108MP0002127_abnormal_cardiovascular_syste0.92440506
109MP0001963_abnormal_hearing_physiology0.92161319
110MP0001970_abnormal_pain_threshold0.91961057
111MP0002693_abnormal_pancreas_physiology0.91937128
112MP0003011_delayed_dark_adaptation0.91460578
113MP0005391_vision/eye_phenotype0.91397701
114MP0010329_abnormal_lipoprotein_level0.90627614
115MP0001286_abnormal_eye_development0.90323686
116MP0000230_abnormal_systemic_arterial0.90206581
117MP0003567_abnormal_fetal_cardiomyocyte0.89067792
118MP0000639_abnormal_adrenal_gland0.88668608
119MP0000631_abnormal_neuroendocrine_gland0.88576596
120MP0003861_abnormal_nervous_system0.88361082
121MP0003633_abnormal_nervous_system0.88358719
122MP0008775_abnormal_heart_ventricle0.88232411
123MP0001270_distended_abdomen0.88044884
124MP0004145_abnormal_muscle_electrophysio0.87961841
125MP0003119_abnormal_digestive_system0.87417408
126MP0010368_abnormal_lymphatic_system0.86709165
127MP0003953_abnormal_hormone_level0.84151863
128MP0001929_abnormal_gametogenesis0.82362061
129MP0003698_abnormal_male_reproductive0.81247586
130MP0002069_abnormal_eating/drinking_beha0.80378384
131MP0002163_abnormal_gland_morphology0.79852780
132MP0000372_irregular_coat_pigmentation0.79801755
133MP0002078_abnormal_glucose_homeostasis0.79541658
134MP0001664_abnormal_digestion0.79396657
135MP0000647_abnormal_sebaceous_gland0.79204080
136MP0004085_abnormal_heartbeat0.78199130
137MP0002837_dystrophic_cardiac_calcinosis0.77828811
138MP0002160_abnormal_reproductive_system0.77278863
139MP0001919_abnormal_reproductive_system0.76939416
140MP0005535_abnormal_body_temperature0.76604931
141MP0003938_abnormal_ear_development0.76527552
142MP0000465_gastrointestinal_hemorrhage0.76375866
143MP0002066_abnormal_motor_capabilities/c0.75105003
144MP0003786_premature_aging0.74899713
145MP0006054_spinal_hemorrhage0.74222465
146MP0000653_abnormal_sex_gland0.72877831
147MP0002210_abnormal_sex_determination0.72569693
148MP0001186_pigmentation_phenotype0.69690235
149MP0003724_increased_susceptibility_to0.69618639
150MP0001324_abnormal_eye_pigmentation0.69328460
151MP0001905_abnormal_dopamine_level0.68301029

Predicted human phenotypes

RankGene SetZ-score
1Hypothermia (HP:0002045)4.76016128
2Febrile seizures (HP:0002373)4.46943481
3Abnormal hair whorl (HP:0010721)4.41475023
4Focal motor seizures (HP:0011153)4.19713016
5Epileptic encephalopathy (HP:0200134)3.57570990
6Amyotrophic lateral sclerosis (HP:0007354)3.54460559
7Nephronophthisis (HP:0000090)3.43145044
8Abnormality of the labia minora (HP:0012880)3.39877860
9Atonic seizures (HP:0010819)3.25554331
10Polyphagia (HP:0002591)3.12287687
11Nephrogenic diabetes insipidus (HP:0009806)3.11126401
12True hermaphroditism (HP:0010459)3.10941195
13Hyperventilation (HP:0002883)3.10159825
14Blue irides (HP:0000635)3.08031828
15Chronic hepatic failure (HP:0100626)3.03288875
16Pancreatic fibrosis (HP:0100732)2.99447734
17Medial flaring of the eyebrow (HP:0010747)2.98714933
18Congenital primary aphakia (HP:0007707)2.97511874
19Molar tooth sign on MRI (HP:0002419)2.94752472
20Abnormality of midbrain morphology (HP:0002418)2.94752472
21Focal seizures (HP:0007359)2.90743614
22Abnormality of the renal medulla (HP:0100957)2.89644420
23Cortical dysplasia (HP:0002539)2.87642949
24Symptomatic seizures (HP:0011145)2.86145976
25Abnormal rod and cone electroretinograms (HP:0008323)2.85259307
26Specific learning disability (HP:0001328)2.84412861
27Gait imbalance (HP:0002141)2.83231377
28Conjugated hyperbilirubinemia (HP:0002908)2.80689121
29Type I transferrin isoform profile (HP:0003642)2.75954154
30Drooling (HP:0002307)2.75571204
31Retinal dysplasia (HP:0007973)2.74293746
32Hypoglycemic seizures (HP:0002173)2.66608372
33Decreased circulating renin level (HP:0003351)2.66551072
34Pheochromocytoma (HP:0002666)2.63646613
35Poor coordination (HP:0002370)2.62831983
36Alveolar cell carcinoma (HP:0006519)2.56363034
37Enlarged kidneys (HP:0000105)2.54791272
38Hyperglycinemia (HP:0002154)2.54504188
39Renal cortical cysts (HP:0000803)2.54118093
40Excessive salivation (HP:0003781)2.52498430
41Generalized hypopigmentation of hair (HP:0011358)2.50928095
42Pachygyria (HP:0001302)2.50234042
43Congenital stationary night blindness (HP:0007642)2.49172004
44Pigmentary retinal degeneration (HP:0001146)2.49142888
45Protruding tongue (HP:0010808)2.48115044
46Postaxial hand polydactyly (HP:0001162)2.46989191
47Neuroendocrine neoplasm (HP:0100634)2.46847100
48Broad foot (HP:0001769)2.45485730
49Fair hair (HP:0002286)2.43403123
50Absent speech (HP:0001344)2.42407359
51Peripheral hypomyelination (HP:0007182)2.42366758
52Colon cancer (HP:0003003)2.41867611
53Absent rod-and cone-mediated responses on ERG (HP:0007688)2.40669921
54Atrophy/Degeneration involving motor neurons (HP:0007373)2.40659958
55Methylmalonic acidemia (HP:0002912)2.40288856
56Progressive inability to walk (HP:0002505)2.38942486
57Inability to walk (HP:0002540)2.36659344
58Lissencephaly (HP:0001339)2.35804835
59Hypoplastic pelvis (HP:0008839)2.34466279
60Oligomenorrhea (HP:0000876)2.31038961
61Broad alveolar ridges (HP:0000187)2.29764139
62Tubulointerstitial nephritis (HP:0001970)2.27459320
63Aplasia/Hypoplasia of the sternum (HP:0006714)2.27145783
64Curly hair (HP:0002212)2.26484671
65Attenuation of retinal blood vessels (HP:0007843)2.24160169
66Adactyly (HP:0009776)2.21406610
67Abnormality of the intrinsic pathway (HP:0010989)2.15843767
68Hemiparesis (HP:0001269)2.15784717
69Papillary thyroid carcinoma (HP:0002895)2.14068040
70Aplasia/Hypoplasia of the fovea (HP:0008060)2.13881443
71Hypoplasia of the fovea (HP:0007750)2.13881443
72Limb hypertonia (HP:0002509)2.13183085
73Generalized aminoaciduria (HP:0002909)2.12059168
74Genital tract atresia (HP:0001827)2.11748512
75Neoplasm of the tracheobronchial system (HP:0100552)2.11044879
76Neonatal hypoglycemia (HP:0001998)2.10843933
77Sclerocornea (HP:0000647)2.10404798
78Osteomalacia (HP:0002749)2.10402033
79Intestinal atresia (HP:0011100)2.09077837
80Mitral stenosis (HP:0001718)2.07433139
81Abolished electroretinogram (ERG) (HP:0000550)2.06655089
82Gaze-evoked nystagmus (HP:0000640)2.06298517
83Aplasia/Hypoplasia of the tongue (HP:0010295)2.06267830
84Pancreatic islet-cell hyperplasia (HP:0004510)2.05894741
85Vaginal atresia (HP:0000148)2.03709029
86Broad-based gait (HP:0002136)2.03421087
87Narrow forehead (HP:0000341)2.02399350
88Acute necrotizing encephalopathy (HP:0006965)2.02338583
89Anencephaly (HP:0002323)2.01962690
90Congenital hepatic fibrosis (HP:0002612)2.01949211
91Long foot (HP:0001833)2.01232740
92Occipital encephalocele (HP:0002085)1.99286808
93Medulloblastoma (HP:0002885)1.99153488
94Abnormality of the nasal septum (HP:0000419)1.98498463
95Chorioretinal atrophy (HP:0000533)1.98289717
96Central scotoma (HP:0000603)1.96720492
97Thyroid carcinoma (HP:0002890)1.95897052
98Absent eyebrow (HP:0002223)1.95834402
99Progressive cerebellar ataxia (HP:0002073)1.95636303
100Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.95532979
101Abnormal protein N-linked glycosylation (HP:0012347)1.95532979
102Abnormal protein glycosylation (HP:0012346)1.95532979
103Abnormal glycosylation (HP:0012345)1.95532979
104Decreased lacrimation (HP:0000633)1.95272737
105Pancreatic cysts (HP:0001737)1.95269024
106Hepatocellular necrosis (HP:0001404)1.94667231
107Hip dysplasia (HP:0001385)1.94059501
108Dialeptic seizures (HP:0011146)1.93882084
109Thyroid-stimulating hormone excess (HP:0002925)1.91837008
110Volvulus (HP:0002580)1.91725584
111Tubulointerstitial abnormality (HP:0001969)1.91596799
112Prolonged partial thromboplastin time (HP:0003645)1.91351859
113Methylmalonic aciduria (HP:0012120)1.91243030
114Decreased testicular size (HP:0008734)1.90836592
115Renal tubular acidosis (HP:0001947)1.89982637
116Myokymia (HP:0002411)1.88286272
117Abnormality of incisor morphology (HP:0011063)1.87916212
118Short tibia (HP:0005736)1.87152507
119Split foot (HP:0001839)1.87105196
120Cystic liver disease (HP:0006706)1.86733048
121Anophthalmia (HP:0000528)1.86345951
122Micropenis (HP:0000054)1.85886344
123Failure to thrive in infancy (HP:0001531)1.85623455
124Abnormality of the fovea (HP:0000493)1.84883402
125Abnormal mitochondria in muscle tissue (HP:0008316)1.84872207
126Short foot (HP:0001773)1.84747400
127Epileptiform EEG discharges (HP:0011182)1.84500516
128Progressive macrocephaly (HP:0004481)1.84238438
129Dyschromatopsia (HP:0007641)1.83832109
130Oligodactyly (hands) (HP:0001180)1.83590580
131Esotropia (HP:0000565)1.81437434
132Bony spicule pigmentary retinopathy (HP:0007737)1.81373014
133Astigmatism (HP:0000483)1.80601858
134Multicystic kidney dysplasia (HP:0000003)1.80154396
135Pendular nystagmus (HP:0012043)1.79901233
136Bradycardia (HP:0001662)1.79684914
137Aplasia/Hypoplasia of the tibia (HP:0005772)1.79673152
138Retinitis pigmentosa (HP:0000510)1.78467352
139Hyperinsulinemic hypoglycemia (HP:0000825)1.77744759
140Growth hormone deficiency (HP:0000824)1.77444416
141Abnormal eating behavior (HP:0100738)1.76793575
142Aganglionic megacolon (HP:0002251)1.75609087
143Limb dystonia (HP:0002451)1.75395880
144Acute encephalopathy (HP:0006846)1.74760730
145Increased CSF lactate (HP:0002490)1.74654789
146Supernumerary spleens (HP:0009799)1.74634711
147Cerebral hypomyelination (HP:0006808)1.73799077
148Preaxial hand polydactyly (HP:0001177)1.73016363
149Type II lissencephaly (HP:0007260)1.72559928
150Insulin-resistant diabetes mellitus (HP:0000831)1.72512245
151Decreased central vision (HP:0007663)1.72043436
152Abnormality of the renal cortex (HP:0011035)1.71475678
153Complement deficiency (HP:0004431)1.70736789
154Aplasia/Hypoplasia of the lens (HP:0008063)1.70706657
155Hypoplastic left heart (HP:0004383)1.70596851
156Microvesicular hepatic steatosis (HP:0001414)1.70290574
157Narrow nasal bridge (HP:0000446)1.69869947
158Neoplasm of the adrenal gland (HP:0100631)1.69355831
159Increased corneal curvature (HP:0100692)1.69325073
160Keratoconus (HP:0000563)1.69325073
161Hepatoblastoma (HP:0002884)1.69025743
162Poor suck (HP:0002033)1.68228269
163Postaxial foot polydactyly (HP:0001830)1.67829156
164Joint hemorrhage (HP:0005261)1.67232417
165Renal dysplasia (HP:0000110)1.66534414
166Intestinal fistula (HP:0100819)1.65612412
167Cystic hygroma (HP:0000476)1.63243895
168Scanning speech (HP:0002168)1.63026670
169Sleep apnea (HP:0010535)1.62966208
170Optic nerve hypoplasia (HP:0000609)1.62640651
171Bile duct proliferation (HP:0001408)1.62357936
172Abnormal biliary tract physiology (HP:0012439)1.62357936

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B5.32030554
2CASK4.62396325
3AKT33.71361749
4WNK33.69679601
5MARK13.43503408
6MAP4K23.24509251
7BCR3.19332189
8INSRR2.71242501
9SGK22.71136378
10TRIM282.66677254
11BCKDK2.66399203
12MAP2K72.50590689
13CSNK1G22.39083388
14MKNK22.26692042
15NEK62.22287257
16CSNK1G32.15907784
17ZAK2.14803270
18FRK2.14783580
19CSNK1A1L2.05930570
20SGK32.02433069
21NTRK32.01043642
22BMPR21.94405723
23MAP3K141.90054764
24CSNK1G11.89545545
25DYRK21.88805477
26SIK31.87282557
27SGK2231.78286471
28SGK4941.78286471
29SRPK11.76152364
30MAP3K121.74820812
31NUAK11.66039163
32NEK11.63337989
33MKNK11.57217694
34ACVR1B1.55762748
35MYLK1.49623681
36NTRK21.47907367
37TNIK1.44952454
38YES11.42876682
39IRAK31.41151029
40ERBB31.41111469
41PLK21.33364571
42TIE11.31688030
43PINK11.29936304
44TXK1.27364216
45TSSK61.22508473
46GRK71.21410067
47MINK11.21156362
48MAPK71.20264350
49ADRBK21.20021620
50MAP3K41.16214381
51PAK31.15516493
52STK38L1.11039255
53EPHA31.09818372
54TNK21.08499397
55BRD41.06464635
56LATS11.05069752
57SIK21.04873258
58MAPK131.01951230
59CDK81.00683954
60PIK3CA0.99816529
61PRKCH0.99242218
62GRK10.98990215
63RPS6KA40.98963308
64CDK30.98847960
65PDK20.92007939
66IRAK40.90770663
67MUSK0.89374062
68CCNB10.88279538
69EPHA40.87533518
70PRKCE0.85766714
71MAPK150.84231120
72CAMKK20.82845605
73STK240.82533075
74DAPK10.79265316
75DAPK20.78011538
76DYRK30.77199938
77TEC0.74904042
78VRK10.73725378
79FGFR30.72866136
80DYRK1B0.72696796
81PRKCG0.71886301
82FGFR20.71874346
83TGFBR20.70891130
84BMPR1B0.70070874
85RPS6KB10.68896985
86PAK60.68238023
87NEK90.67474470
88OBSCN0.64311037
89STK160.64268833
90FER0.62126537
91TRPM70.61123624
92OXSR10.60239611
93SGK10.58319808
94TLK10.57128694
95MAP3K60.55931659
96CHUK0.55894355
97CDK50.55871819
98PLK40.55367509
99TGFBR10.55058789
100EIF2AK20.53633865
101UHMK10.51847983
102MAP2K40.51777828
103LIMK10.48727117
104CAMK2A0.48511660
105MAP3K50.47916864
106TAOK30.47682287
107FLT30.47030879
108RPS6KA20.46578682
109PRKCZ0.46267837
110CDK190.45907705
111CAMKK10.44119411
112CDC42BPA0.43245374
113IKBKE0.42706691
114PLK10.41870045
115JAK10.41365605
116MAPK120.40742577
117CSNK1A10.40194701
118CSNK1D0.38883061
119WNK10.38761637
120RPS6KA50.38463027
121PIK3CG0.36457708
122CAMK2B0.36091951
123CDK140.35283322
124STK110.35242256
125CAMK40.35054376
126DYRK1A0.34881023
127BUB10.34728275
128ATM0.34350643
129PASK0.34221448
130CAMK10.34215123
131PLK30.33629513
132RPS6KA60.33512983
133RPS6KL10.33399040
134RPS6KC10.33399040
135PRKG10.32773801
136EIF2AK30.32617578
137BRAF0.32011879
138PRKD30.30952043
139BRSK20.30870893
140KSR10.30695425
141IGF1R0.30511349
142PRKACA0.30244078
143GRK50.30009536
144CAMK2G0.29910821
145CAMK2D0.29492376
146IKBKB0.29423297
147PNCK0.29225676
148BRSK10.28007746
149CDK180.27295536
150CDC70.27277345
151PRKACB0.27044093
152RAF10.26708451
153FES0.24629593
154PRKCQ0.24340209
155PHKG20.24059787
156PHKG10.24059787

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.42389212
2Phototransduction_Homo sapiens_hsa047443.29721350
3Nicotine addiction_Homo sapiens_hsa050333.07449317
4Synaptic vesicle cycle_Homo sapiens_hsa047212.82744751
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.73932168
6Maturity onset diabetes of the young_Homo sapiens_hsa049502.72938092
7Protein export_Homo sapiens_hsa030602.54681629
8Fanconi anemia pathway_Homo sapiens_hsa034602.25277498
9Non-homologous end-joining_Homo sapiens_hsa034502.24125304
10Collecting duct acid secretion_Homo sapiens_hsa049662.20641477
11Circadian entrainment_Homo sapiens_hsa047132.17322155
12SNARE interactions in vesicular transport_Homo sapiens_hsa041302.11299485
13Insulin secretion_Homo sapiens_hsa049112.09026070
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.06489868
15Basal transcription factors_Homo sapiens_hsa030222.01884096
16Vibrio cholerae infection_Homo sapiens_hsa051102.01055020
17Morphine addiction_Homo sapiens_hsa050321.98995896
18RNA degradation_Homo sapiens_hsa030181.97847668
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.97422805
20GABAergic synapse_Homo sapiens_hsa047271.96732186
21Olfactory transduction_Homo sapiens_hsa047401.96504327
22RNA polymerase_Homo sapiens_hsa030201.90703760
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.85350029
24Taste transduction_Homo sapiens_hsa047421.84916917
25Steroid biosynthesis_Homo sapiens_hsa001001.81018310
26Oxidative phosphorylation_Homo sapiens_hsa001901.80557359
27Amphetamine addiction_Homo sapiens_hsa050311.78164189
28Parkinsons disease_Homo sapiens_hsa050121.72184205
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69251807
30Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.60268173
31Base excision repair_Homo sapiens_hsa034101.56337030
32Nucleotide excision repair_Homo sapiens_hsa034201.50961324
33Glutamatergic synapse_Homo sapiens_hsa047241.42321067
34Long-term potentiation_Homo sapiens_hsa047201.38474102
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.34187880
36Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.32345636
37Primary bile acid biosynthesis_Homo sapiens_hsa001201.32117122
38Peroxisome_Homo sapiens_hsa041461.27226233
39Serotonergic synapse_Homo sapiens_hsa047261.24717265
40Fatty acid elongation_Homo sapiens_hsa000621.20455276
41Axon guidance_Homo sapiens_hsa043601.18574613
42ABC transporters_Homo sapiens_hsa020101.18364909
43Huntingtons disease_Homo sapiens_hsa050161.17827214
44Proteasome_Homo sapiens_hsa030501.14189592
45Ether lipid metabolism_Homo sapiens_hsa005651.13521837
46Circadian rhythm_Homo sapiens_hsa047101.12812427
47Dopaminergic synapse_Homo sapiens_hsa047281.11504477
48Calcium signaling pathway_Homo sapiens_hsa040201.11067935
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.10890153
50Aldosterone synthesis and secretion_Homo sapiens_hsa049251.09437049
51Cocaine addiction_Homo sapiens_hsa050301.07304935
52Rheumatoid arthritis_Homo sapiens_hsa053231.07132629
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.06249790
54Steroid hormone biosynthesis_Homo sapiens_hsa001401.05269294
55Type I diabetes mellitus_Homo sapiens_hsa049401.04576996
56Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.04095344
57Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.03593147
58Sulfur metabolism_Homo sapiens_hsa009201.02231288
59Cholinergic synapse_Homo sapiens_hsa047250.99924247
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.99186344
61RNA transport_Homo sapiens_hsa030130.95303763
62Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.95029675
63Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.94053067
64Salivary secretion_Homo sapiens_hsa049700.91646372
65Alzheimers disease_Homo sapiens_hsa050100.89550852
66Linoleic acid metabolism_Homo sapiens_hsa005910.89354619
67Complement and coagulation cascades_Homo sapiens_hsa046100.88858238
68Renin secretion_Homo sapiens_hsa049240.88668668
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88606388
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.88164500
71Homologous recombination_Homo sapiens_hsa034400.87772078
72Phenylalanine metabolism_Homo sapiens_hsa003600.87044871
73Other glycan degradation_Homo sapiens_hsa005110.85942757
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85212368
75Hedgehog signaling pathway_Homo sapiens_hsa043400.84396843
76Propanoate metabolism_Homo sapiens_hsa006400.83239938
77Mismatch repair_Homo sapiens_hsa034300.81243745
78Oocyte meiosis_Homo sapiens_hsa041140.81048509
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.80617422
80cAMP signaling pathway_Homo sapiens_hsa040240.77036569
81Type II diabetes mellitus_Homo sapiens_hsa049300.76111869
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.76084758
83Purine metabolism_Homo sapiens_hsa002300.75579803
84Galactose metabolism_Homo sapiens_hsa000520.74274643
85Retinol metabolism_Homo sapiens_hsa008300.70864456
86Regulation of autophagy_Homo sapiens_hsa041400.67781670
87Starch and sucrose metabolism_Homo sapiens_hsa005000.67685542
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67354278
89Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.66876153
90Ovarian steroidogenesis_Homo sapiens_hsa049130.66584406
91Long-term depression_Homo sapiens_hsa047300.64245390
92N-Glycan biosynthesis_Homo sapiens_hsa005100.63950140
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.63512363
94Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61755142
95beta-Alanine metabolism_Homo sapiens_hsa004100.61719187
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61486682
97Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.60266987
98Sphingolipid metabolism_Homo sapiens_hsa006000.60222422
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59733412
100Staphylococcus aureus infection_Homo sapiens_hsa051500.59018348
101Tyrosine metabolism_Homo sapiens_hsa003500.58964102
102Vitamin digestion and absorption_Homo sapiens_hsa049770.58756803
103Fatty acid metabolism_Homo sapiens_hsa012120.57817316
104Spliceosome_Homo sapiens_hsa030400.57791022
105Fatty acid degradation_Homo sapiens_hsa000710.57113423
106Selenocompound metabolism_Homo sapiens_hsa004500.56441536
107Phagosome_Homo sapiens_hsa041450.56331319
108Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.54996080
109Cardiac muscle contraction_Homo sapiens_hsa042600.54571993
110Tryptophan metabolism_Homo sapiens_hsa003800.53853737
111Arachidonic acid metabolism_Homo sapiens_hsa005900.53608693
112Metabolic pathways_Homo sapiens_hsa011000.52484776
113Pyruvate metabolism_Homo sapiens_hsa006200.52357582
114Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.52212501
115Thyroid hormone synthesis_Homo sapiens_hsa049180.51581246
116Inositol phosphate metabolism_Homo sapiens_hsa005620.49687001
117Pyrimidine metabolism_Homo sapiens_hsa002400.49605573
118Folate biosynthesis_Homo sapiens_hsa007900.48962493
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.47372718
120Hippo signaling pathway_Homo sapiens_hsa043900.47370123
121Fructose and mannose metabolism_Homo sapiens_hsa000510.46710855
122Gastric acid secretion_Homo sapiens_hsa049710.44672345
123Gap junction_Homo sapiens_hsa045400.44170680
124cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44021160
125Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.42936376
126Glucagon signaling pathway_Homo sapiens_hsa049220.42162533
127Pancreatic secretion_Homo sapiens_hsa049720.41452190
128Nitrogen metabolism_Homo sapiens_hsa009100.39898293
129Vitamin B6 metabolism_Homo sapiens_hsa007500.38443359
130Lysosome_Homo sapiens_hsa041420.38152531
131Autoimmune thyroid disease_Homo sapiens_hsa053200.36707478
132Oxytocin signaling pathway_Homo sapiens_hsa049210.36602311
133Butanoate metabolism_Homo sapiens_hsa006500.35936587
134Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35846180
135Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35574735
136mRNA surveillance pathway_Homo sapiens_hsa030150.35403389
137Caffeine metabolism_Homo sapiens_hsa002320.35097402
138Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33583141
139Chemical carcinogenesis_Homo sapiens_hsa052040.32666523
140Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.32665038
141Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30982763
142Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30143621
143Dilated cardiomyopathy_Homo sapiens_hsa054140.29824146
144Ras signaling pathway_Homo sapiens_hsa040140.29798790
145Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28688071

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