ZSWIM5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)4.51408754
2cell migration in hindbrain (GO:0021535)4.35055217
3layer formation in cerebral cortex (GO:0021819)4.25815635
4vocalization behavior (GO:0071625)4.24106725
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.18918547
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.10936571
7regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.99559670
8locomotory exploration behavior (GO:0035641)3.98813553
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.93242397
10auditory behavior (GO:0031223)3.83077293
11innervation (GO:0060384)3.75909182
12behavioral response to nicotine (GO:0035095)3.72072084
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.67263482
14positive regulation of synapse maturation (GO:0090129)3.64951652
15protein localization to synapse (GO:0035418)3.55577408
16regulation of synapse structural plasticity (GO:0051823)3.53393286
17glial cell proliferation (GO:0014009)3.51455702
18regulation of synaptic vesicle exocytosis (GO:2000300)3.49664084
19prepulse inhibition (GO:0060134)3.47109109
20dendritic spine morphogenesis (GO:0060997)3.45960686
21synaptic vesicle maturation (GO:0016188)3.45419406
22synaptic vesicle exocytosis (GO:0016079)3.41310882
23response to auditory stimulus (GO:0010996)3.40454979
24pyrimidine nucleobase catabolic process (GO:0006208)3.37149385
25neuron recognition (GO:0008038)3.35399025
26dendrite morphogenesis (GO:0048813)3.29832152
27exploration behavior (GO:0035640)3.28330807
28synaptic vesicle docking involved in exocytosis (GO:0016081)3.27635171
29regulation of glutamate receptor signaling pathway (GO:1900449)3.27163242
30axonal fasciculation (GO:0007413)3.23960051
31cell-cell junction maintenance (GO:0045217)3.23171808
32cellular potassium ion homeostasis (GO:0030007)3.18500046
33establishment of mitochondrion localization (GO:0051654)3.15117015
34synaptic transmission, glutamatergic (GO:0035249)3.14370920
35ionotropic glutamate receptor signaling pathway (GO:0035235)3.10037861
36embryonic retina morphogenesis in camera-type eye (GO:0060059)3.08085857
37negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.07738350
38regulation of synaptic vesicle transport (GO:1902803)3.06899751
39positive regulation of synaptic transmission, GABAergic (GO:0032230)3.05334665
40glutamate secretion (GO:0014047)3.02381235
41response to pheromone (GO:0019236)3.01059895
42cerebellar Purkinje cell differentiation (GO:0021702)2.99879360
43cell junction maintenance (GO:0034331)2.97722290
44pre-miRNA processing (GO:0031054)2.97280050
45establishment of nucleus localization (GO:0040023)2.96747586
46central nervous system projection neuron axonogenesis (GO:0021952)2.94019931
47mechanosensory behavior (GO:0007638)2.93386997
48neurotransmitter secretion (GO:0007269)2.92912094
49neuromuscular process controlling balance (GO:0050885)2.88173136
50regulation of neuronal synaptic plasticity (GO:0048168)2.88129766
51glutamate receptor signaling pathway (GO:0007215)2.86720739
52neurotransmitter-gated ion channel clustering (GO:0072578)2.85874637
53cell communication by electrical coupling (GO:0010644)2.85835303
54body morphogenesis (GO:0010171)2.83389054
55regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.83070988
56neuron-neuron synaptic transmission (GO:0007270)2.82884428
57startle response (GO:0001964)2.82344986
58membrane hyperpolarization (GO:0060081)2.81078315
59gamma-aminobutyric acid transport (GO:0015812)2.80484834
60short-term memory (GO:0007614)2.80179395
61somite development (GO:0061053)2.76231077
62positive regulation of dendritic spine morphogenesis (GO:0061003)2.75339755
63synapse assembly (GO:0007416)2.75037562
64neurofilament cytoskeleton organization (GO:0060052)2.74570042
65very-low-density lipoprotein particle assembly (GO:0034379)2.73575640
66piRNA metabolic process (GO:0034587)2.72131401
67negative regulation of sodium ion transport (GO:0010766)2.72016030
68cochlea development (GO:0090102)2.71394220
69C4-dicarboxylate transport (GO:0015740)2.71206963
70positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.70676141
71postsynaptic membrane organization (GO:0001941)2.69875602
72intestinal cholesterol absorption (GO:0030299)2.69493848
73plasma lipoprotein particle assembly (GO:0034377)2.68535354
74head development (GO:0060322)2.68211834
75regulation of synapse maturation (GO:0090128)2.67957769
76regulation of long-term neuronal synaptic plasticity (GO:0048169)2.66150973
77dopamine receptor signaling pathway (GO:0007212)2.65437291
78nucleobase catabolic process (GO:0046113)2.65174690
79membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.64718486
80neuronal ion channel clustering (GO:0045161)2.64684989
81stress granule assembly (GO:0034063)2.64150054
82regulation of dendritic spine morphogenesis (GO:0061001)2.63463094
83presynaptic membrane assembly (GO:0097105)2.62422123
84regulation of NFAT protein import into nucleus (GO:0051532)2.62289016
85eye photoreceptor cell differentiation (GO:0001754)2.60138161
86photoreceptor cell differentiation (GO:0046530)2.60138161
87hippocampus development (GO:0021766)2.59633461
88regulation of synaptic transmission, glutamatergic (GO:0051966)2.59168597
89striatum development (GO:0021756)2.58983888
90SMAD protein signal transduction (GO:0060395)2.58036924
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.56739343
92positive regulation of membrane potential (GO:0045838)2.56605539
93transmission of nerve impulse (GO:0019226)2.56564050
94negative regulation of microtubule polymerization (GO:0031115)2.55995075
95positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.53380253
96long-term memory (GO:0007616)2.52403364
97axon extension (GO:0048675)2.52194804
98neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.52147255
99synaptic vesicle endocytosis (GO:0048488)2.51930461
100negative regulation of dendrite development (GO:2000171)2.51712019
101central nervous system myelination (GO:0022010)2.51113737
102axon ensheathment in central nervous system (GO:0032291)2.51113737
103synapse organization (GO:0050808)2.50352861
104urinary tract smooth muscle contraction (GO:0014848)2.49491448
105dendritic spine organization (GO:0097061)2.49406724
106positive regulation of synapse assembly (GO:0051965)2.49042358
107adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.48235015
108spinal cord development (GO:0021510)2.47905855
109sensory perception of smell (GO:0007608)2.46921107
110neuronal action potential propagation (GO:0019227)2.46320095
111negative regulation of cytosolic calcium ion concentration (GO:0051481)2.46181735
112membrane repolarization (GO:0086009)2.45515338
113neuromuscular process (GO:0050905)2.44975716
114apical protein localization (GO:0045176)2.44819079
115cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.44425884
116calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.43757462
117cerebellum development (GO:0021549)2.43753156
118peristalsis (GO:0030432)2.42101372
119cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.42066519
120presynaptic membrane organization (GO:0097090)2.41820456
121regulation of neurotransmitter secretion (GO:0046928)2.40942344
122establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.40324314
123mitochondrion transport along microtubule (GO:0047497)2.40324314
124retinal ganglion cell axon guidance (GO:0031290)2.40076935
125chemosensory behavior (GO:0007635)2.39895138
126regulation of postsynaptic membrane potential (GO:0060078)2.39738684
127regulation of respiratory system process (GO:0044065)2.39470531
128regulation of excitatory postsynaptic membrane potential (GO:0060079)2.38520907
129potassium ion homeostasis (GO:0055075)2.38277646
130regulation of synaptic transmission, GABAergic (GO:0032228)2.37676573
131response to follicle-stimulating hormone (GO:0032354)2.36169828
132olfactory bulb development (GO:0021772)2.35398451
133neuromuscular synaptic transmission (GO:0007274)2.31916643
134regulation of axon guidance (GO:1902667)2.29573783
135glucocorticoid biosynthetic process (GO:0006704)2.28290735
136high-density lipoprotein particle remodeling (GO:0034375)2.28105131
137vitamin transmembrane transport (GO:0035461)2.28019297
138nephron epithelium morphogenesis (GO:0072088)2.26289870
139nephron tubule morphogenesis (GO:0072078)2.26289870
140lung epithelium development (GO:0060428)2.25043448
141response to dietary excess (GO:0002021)2.24500956
142forebrain neuron differentiation (GO:0021879)2.24341016
143protein carboxylation (GO:0018214)2.24163106
144peptidyl-glutamic acid carboxylation (GO:0017187)2.24163106
145reverse cholesterol transport (GO:0043691)2.22847832
146regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.22683844
147protein-lipid complex assembly (GO:0065005)2.21080599
148cellular sodium ion homeostasis (GO:0006883)2.19453336
149ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.18541405
150low-density lipoprotein particle remodeling (GO:0034374)2.18390939
151adult walking behavior (GO:0007628)2.18138448
152regulation of non-canonical Wnt signaling pathway (GO:2000050)2.17059606
153cholesterol efflux (GO:0033344)2.16457514
154regulation of glycogen (starch) synthase activity (GO:2000465)2.14650097
155plasma lipoprotein particle remodeling (GO:0034369)2.14623308
156protein-lipid complex remodeling (GO:0034368)2.14623308
157macromolecular complex remodeling (GO:0034367)2.14623308
158membrane depolarization during action potential (GO:0086010)2.13067256

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.54490196
2RBPJ_22232070_ChIP-Seq_NCS_Mouse2.86839579
3GBX2_23144817_ChIP-Seq_PC3_Human2.81111883
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.68566984
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.68096433
6* REST_21632747_ChIP-Seq_MESCs_Mouse2.56690199
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.45207653
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.40367409
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.37504120
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.31398079
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.31240553
12RNF2_18974828_ChIP-Seq_MESCs_Mouse2.28066466
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.28066466
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.26980336
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.25543114
16EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.19299486
17RARB_27405468_Chip-Seq_BRAIN_Mouse2.18860685
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.08621144
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.07598889
20CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.04549401
21* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.00054799
22* REST_18959480_ChIP-ChIP_MESCs_Mouse1.99518258
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.98056249
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.96495856
25SUZ12_27294783_Chip-Seq_ESCs_Mouse1.95810589
26* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.95428786
27DROSHA_22980978_ChIP-Seq_HELA_Human1.93218606
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.92853666
29SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.88668509
30SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70219760
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69507641
32ERG_21242973_ChIP-ChIP_JURKAT_Human1.68104285
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.58728449
34RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.53965882
35RNF2_27304074_Chip-Seq_NSC_Mouse1.50785095
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.46191809
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.45397222
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.44906317
39ZNF274_21170338_ChIP-Seq_K562_Hela1.43846302
40RING1B_27294783_Chip-Seq_NPCs_Mouse1.43761790
41CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.42539594
42RING1B_27294783_Chip-Seq_ESCs_Mouse1.42064016
43GATA1_26923725_Chip-Seq_HPCs_Mouse1.39391524
44IGF1R_20145208_ChIP-Seq_DFB_Human1.38715205
45RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.37567756
46TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37479947
47POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.37479947
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.36825988
49SMAD4_21799915_ChIP-Seq_A2780_Human1.35436462
50* FOXA2_19822575_ChIP-Seq_HepG2_Human1.31289264
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.27702351
52* STAT3_23295773_ChIP-Seq_U87_Human1.26928775
53* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.26829177
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.25682153
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.25491999
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.25417559
57ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23853441
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23692004
59PIAS1_25552417_ChIP-Seq_VCAP_Human1.23149131
60* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.22553805
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.22498165
62AR_19668381_ChIP-Seq_PC3_Human1.20659949
63* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.19513167
64BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.18818021
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.18539322
66GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18287933
67MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.17720651
68WT1_25993318_ChIP-Seq_PODOCYTE_Human1.16852741
69SMAD3_21741376_ChIP-Seq_ESCs_Human1.15534813
70* KDM2B_26808549_Chip-Seq_K562_Human1.12462402
71RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.12432180
72* P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11948740
73TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11522901
74VDR_22108803_ChIP-Seq_LS180_Human1.10623154
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09295656
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.08626714
77AR_21572438_ChIP-Seq_LNCaP_Human1.08607741
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08291650
79POU3F2_20337985_ChIP-ChIP_501MEL_Human1.06638856
80ARNT_22903824_ChIP-Seq_MCF-7_Human1.06348739
81WDR5_24793694_ChIP-Seq_LNCAP_Human1.06265429
82ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05512490
83AHR_22903824_ChIP-Seq_MCF-7_Human1.04725350
84CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.04492363
85POU5F1_16153702_ChIP-ChIP_HESCs_Human1.03308769
86P300_19829295_ChIP-Seq_ESCs_Human1.03090625
87DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.03027283
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02767922
89TCF4_23295773_ChIP-Seq_U87_Human1.02189166
90AR_25329375_ChIP-Seq_VCAP_Human1.01651056
91NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01083808
92CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01061100
93TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99373753
94ZFP281_27345836_Chip-Seq_ESCs_Mouse0.99107733
95TAF15_26573619_Chip-Seq_HEK293_Human0.97798975
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.97457642
97CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97209581
98ZFP57_27257070_Chip-Seq_ESCs_Mouse0.97056433
99CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96952983
100* SMAD4_21741376_ChIP-Seq_HESCs_Human0.96707448
101SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95123075
102EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.94808470
103ISL1_27105846_Chip-Seq_CPCs_Mouse0.94565932
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94035504
105RUNX2_22187159_ChIP-Seq_PCA_Human0.94018456
106* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.93988536
107OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93922766
108STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93735526
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93590490
110FUS_26573619_Chip-Seq_HEK293_Human0.92767789
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.92740681
112* TCF4_18268006_ChIP-ChIP_LS174T_Human0.91955141
113TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.91449310
114TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91326806
115ESR1_15608294_ChIP-ChIP_MCF-7_Human0.91032417
116FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.89994479
117TP53_20018659_ChIP-ChIP_R1E_Mouse0.88981016
118ER_23166858_ChIP-Seq_MCF-7_Human0.86935074
119LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86427234

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.75989360
2MP0003880_abnormal_central_pattern3.12270363
3MP0004270_analgesia3.11692922
4MP0005423_abnormal_somatic_nervous2.99770578
5MP0003635_abnormal_synaptic_transmissio2.69223391
6MP0003123_paternal_imprinting2.62098127
7MP0001984_abnormal_olfaction2.58196171
8MP0002063_abnormal_learning/memory/cond2.43600828
9MP0002653_abnormal_ependyma_morphology2.40371323
10MP0000778_abnormal_nervous_system2.34064529
11MP0002822_catalepsy2.18313784
12MP0005646_abnormal_pituitary_gland2.08105738
13MP0001486_abnormal_startle_reflex2.07342088
14MP0002184_abnormal_innervation2.06331414
15MP0002734_abnormal_mechanical_nocicepti2.06208147
16MP0002572_abnormal_emotion/affect_behav1.97739206
17MP0004858_abnormal_nervous_system1.96966910
18MP0002909_abnormal_adrenal_gland1.94879396
19MP0009745_abnormal_behavioral_response1.91286785
20MP0002064_seizures1.84227205
21MP0009046_muscle_twitch1.78656630
22MP0001968_abnormal_touch/_nociception1.76067663
23MP0000569_abnormal_digit_pigmentation1.74885355
24MP0000566_synostosis1.72136231
25MP0004885_abnormal_endolymph1.70238491
26MP0002272_abnormal_nervous_system1.69334968
27MP0001529_abnormal_vocalization1.68767557
28MP0000955_abnormal_spinal_cord1.67420265
29MP0008877_abnormal_DNA_methylation1.65610333
30MP0005551_abnormal_eye_electrophysiolog1.64911127
31MP0002557_abnormal_social/conspecific_i1.63402990
32MP0004811_abnormal_neuron_physiology1.62824931
33MP0006276_abnormal_autonomic_nervous1.60657537
34MP0005394_taste/olfaction_phenotype1.59123901
35MP0005499_abnormal_olfactory_system1.59123901
36MP0001188_hyperpigmentation1.57599391
37MP0002638_abnormal_pupillary_reflex1.55433819
38MP0006072_abnormal_retinal_apoptosis1.55148320
39MP0009384_cardiac_valve_regurgitation1.55106355
40MP0002882_abnormal_neuron_morphology1.53704878
41MP0002733_abnormal_thermal_nociception1.53195411
42MP0003787_abnormal_imprinting1.51992472
43MP0003195_calcinosis1.51486834
44MP0002067_abnormal_sensory_capabilities1.50828306
45MP0001502_abnormal_circadian_rhythm1.45108839
46MP0004133_heterotaxia1.44904470
47MP0000631_abnormal_neuroendocrine_gland1.43073557
48MP0003890_abnormal_embryonic-extraembry1.41590142
49MP0004924_abnormal_behavior1.39882169
50MP0005386_behavior/neurological_phenoty1.39882169
51MP0002736_abnormal_nociception_after1.39660631
52MP0002152_abnormal_brain_morphology1.39153437
53MP0006292_abnormal_olfactory_placode1.37448645
54MP0002735_abnormal_chemical_nociception1.37263631
55MP0009780_abnormal_chondrocyte_physiolo1.35932986
56MP0003942_abnormal_urinary_system1.34671618
57MP0003861_abnormal_nervous_system1.34188512
58MP0005365_abnormal_bile_salt1.34043650
59MP0003329_amyloid_beta_deposits1.33949773
60MP0010329_abnormal_lipoprotein_level1.33889240
61MP0000537_abnormal_urethra_morphology1.30462002
62MP0003567_abnormal_fetal_cardiomyocyte1.29944852
63MP0005187_abnormal_penis_morphology1.25853584
64MP0001970_abnormal_pain_threshold1.24254843
65MP0008995_early_reproductive_senescence1.22076277
66MP0008789_abnormal_olfactory_epithelium1.20717841
67MP0001440_abnormal_grooming_behavior1.20032124
68MP0005253_abnormal_eye_physiology1.19765590
69MP0002752_abnormal_somatic_nervous1.19536703
70MP0004145_abnormal_muscle_electrophysio1.16759091
71MP0002751_abnormal_autonomic_nervous1.16601841
72MP0002160_abnormal_reproductive_system1.12587664
73MP0004742_abnormal_vestibular_system1.12333274
74MP0003121_genomic_imprinting1.11728003
75MP0003119_abnormal_digestive_system1.10408121
76MP0002066_abnormal_motor_capabilities/c1.10398822
77MP0003283_abnormal_digestive_organ1.09097203
78MP0002697_abnormal_eye_size1.08333352
79MP0003385_abnormal_body_wall1.08021896
80MP0000049_abnormal_middle_ear1.07992586
81MP0003136_yellow_coat_color1.07691606
82MP0000639_abnormal_adrenal_gland1.07472408
83MP0005248_abnormal_Harderian_gland1.06824861
84MP0003315_abnormal_perineum_morphology1.05902150
85MP0002229_neurodegeneration1.04978525
86MP0005360_urolithiasis0.99340741
87MP0010386_abnormal_urinary_bladder0.99210532
88MP0005645_abnormal_hypothalamus_physiol0.94205389
89MP0001485_abnormal_pinna_reflex0.94025800
90MP0001293_anophthalmia0.93698881
91MP0008569_lethality_at_weaning0.93682767
92MP0004043_abnormal_pH_regulation0.93590578
93MP0002102_abnormal_ear_morphology0.92453504
94MP0003122_maternal_imprinting0.91794111
95MP0005377_hearing/vestibular/ear_phenot0.90854817
96MP0003878_abnormal_ear_physiology0.90854817
97MP0003632_abnormal_nervous_system0.90483550
98MP0002233_abnormal_nose_morphology0.88766315
99MP0010234_abnormal_vibrissa_follicle0.88552224
100MP0002069_abnormal_eating/drinking_beha0.88314169
101MP0002234_abnormal_pharynx_morphology0.88106485
102MP0003634_abnormal_glial_cell0.87212534
103MP0003115_abnormal_respiratory_system0.86945160
104MP0003937_abnormal_limbs/digits/tail_de0.86691184
105MP0001666_abnormal_nutrient_absorption0.86116535
106MP0000534_abnormal_ureter_morphology0.85844822
107MP0005195_abnormal_posterior_eye0.85321998
108MP0003698_abnormal_male_reproductive0.84020950
109MP0001501_abnormal_sleep_pattern0.83885931
110MP0008961_abnormal_basal_metabolism0.83418479
111MP0001324_abnormal_eye_pigmentation0.83204776
112MP0002938_white_spotting0.82222754
113MP0003879_abnormal_hair_cell0.82053352
114MP0002092_abnormal_eye_morphology0.81360176
115MP0001286_abnormal_eye_development0.80640929
116MP0001963_abnormal_hearing_physiology0.78465963
117MP0010030_abnormal_orbit_morphology0.78249406
118MP0003938_abnormal_ear_development0.76152996
119MP0000462_abnormal_digestive_system0.74720582
120MP0004142_abnormal_muscle_tone0.74027528
121MP0005391_vision/eye_phenotype0.73717920
122MP0001177_atelectasis0.72705504
123MP0005409_darkened_coat_color0.71865224
124MP0003631_nervous_system_phenotype0.71696050
125MP0003137_abnormal_impulse_conducting0.71202385
126MP0001299_abnormal_eye_distance/0.70797056
127MP0004085_abnormal_heartbeat0.68065020
128MP0003755_abnormal_palate_morphology0.67862783
129MP0000026_abnormal_inner_ear0.67811162

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.14432721
2Deep venous thrombosis (HP:0002625)3.25872678
3Action tremor (HP:0002345)3.24260040
4Broad alveolar ridges (HP:0000187)3.19676185
5Focal motor seizures (HP:0011153)2.93701025
6Focal seizures (HP:0007359)2.87954183
7Termporal pattern (HP:0011008)2.74790865
8Insidious onset (HP:0003587)2.74790865
9Progressive cerebellar ataxia (HP:0002073)2.63025853
10Epileptic encephalopathy (HP:0200134)2.54853597
11Vaginal fistula (HP:0004320)2.53027666
12Drooling (HP:0002307)2.50291820
13Excessive salivation (HP:0003781)2.50291820
14Megalencephaly (HP:0001355)2.47327892
15Prolonged partial thromboplastin time (HP:0003645)2.45878895
16Osteomalacia (HP:0002749)2.43984744
17Chronic hepatic failure (HP:0100626)2.43222002
18Febrile seizures (HP:0002373)2.34118095
19EEG with generalized epileptiform discharges (HP:0011198)2.33939855
20Depression (HP:0000716)2.31628214
21Ankle clonus (HP:0011448)2.30832310
22Epileptiform EEG discharges (HP:0011182)2.30799094
23Abnormality of the aortic arch (HP:0012303)2.28206000
24Hyperventilation (HP:0002883)2.27692682
25Hemiparesis (HP:0001269)2.27297945
26Amblyopia (HP:0000646)2.27260024
27Obsessive-compulsive behavior (HP:0000722)2.26384006
28Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.26347942
29Broad palm (HP:0001169)2.23151578
30Epidermoid cyst (HP:0200040)2.21674343
31Astrocytoma (HP:0009592)2.20665819
32Abnormality of the astrocytes (HP:0100707)2.20665819
33Visual hallucinations (HP:0002367)2.20580424
34Alacrima (HP:0000522)2.19790052
35Abnormality of the corticospinal tract (HP:0002492)2.19555273
36Absent eyebrow (HP:0002223)2.18822369
37Abnormality of the lower motor neuron (HP:0002366)2.18065254
38Lissencephaly (HP:0001339)2.17817487
39Rectovaginal fistula (HP:0000143)2.16711178
40Rectal fistula (HP:0100590)2.16711178
41Hypsarrhythmia (HP:0002521)2.14677913
42Oligodactyly (hands) (HP:0001180)2.12886332
43Bicornuate uterus (HP:0000813)2.10344390
44Supranuclear gaze palsy (HP:0000605)2.08420773
45Bony spicule pigmentary retinopathy (HP:0007737)2.07450411
46Thyroid-stimulating hormone excess (HP:0002925)2.07047413
47Impaired vibration sensation in the lower limbs (HP:0002166)2.06061572
48Abnormality of the pubic bones (HP:0003172)2.05849844
49Elfin facies (HP:0004428)2.04874660
50Heterotopia (HP:0002282)2.03130956
51Absent speech (HP:0001344)2.00290475
52Absence seizures (HP:0002121)2.00192538
53Insomnia (HP:0100785)2.00181295
54Dysdiadochokinesis (HP:0002075)1.99799517
55Neoplasm of the heart (HP:0100544)1.99560021
56Truncal ataxia (HP:0002078)1.98468848
57Hepatoblastoma (HP:0002884)1.98071827
58Limb dystonia (HP:0002451)1.98016954
59Cutaneous finger syndactyly (HP:0010554)1.96605001
60Papillary thyroid carcinoma (HP:0002895)1.96437609
61Impaired social interactions (HP:0000735)1.96342681
62Abnormal social behavior (HP:0012433)1.96342681
63Broad-based gait (HP:0002136)1.96331605
64Spastic tetraplegia (HP:0002510)1.95413291
65Central scotoma (HP:0000603)1.94902358
66Hypoplasia of the brainstem (HP:0002365)1.93871788
67Aplasia/Hypoplasia of the brainstem (HP:0007362)1.93871788
68Spastic gait (HP:0002064)1.93423964
69Intestinal fistula (HP:0100819)1.92954490
70Urinary bladder sphincter dysfunction (HP:0002839)1.90845150
71Bifid tongue (HP:0010297)1.90780035
72Hypobetalipoproteinemia (HP:0003563)1.90249951
73Ventricular fibrillation (HP:0001663)1.90198745
74Diastasis recti (HP:0001540)1.89169792
75Pheochromocytoma (HP:0002666)1.87453707
76Amyotrophic lateral sclerosis (HP:0007354)1.87344666
77Intestinal atresia (HP:0011100)1.87314706
78Dialeptic seizures (HP:0011146)1.86991550
79Midline defect of the nose (HP:0004122)1.86451235
80Enlarged kidneys (HP:0000105)1.86358041
81Macroorchidism (HP:0000053)1.85364299
82Aqueductal stenosis (HP:0002410)1.83347509
83Exotropia (HP:0000577)1.83000769
84Torticollis (HP:0000473)1.82571041
85Genetic anticipation (HP:0003743)1.82088285
86Poor eye contact (HP:0000817)1.82086908
87Tubulointerstitial nephritis (HP:0001970)1.82085036
88Pachygyria (HP:0001302)1.81832697
89Aplasia/Hypoplasia of the sternum (HP:0006714)1.81598971
90Urinary urgency (HP:0000012)1.81183466
91Hypoplastic nipples (HP:0002557)1.80468614
92Renovascular hypertension (HP:0100817)1.79502634
93Stereotypic behavior (HP:0000733)1.78129044
94Abnormality of ocular smooth pursuit (HP:0000617)1.77151661
95Menstrual irregularities (HP:0000858)1.77075441
96Gaze-evoked nystagmus (HP:0000640)1.76147236
97Decreased lacrimation (HP:0000633)1.76069995
98Abnormality of the diencephalon (HP:0010662)1.74951007
99Cutaneous syndactyly (HP:0012725)1.74835144
100Abnormality of the vitreous humor (HP:0004327)1.74695555
101Agitation (HP:0000713)1.74621209
102Aplasia involving bones of the extremities (HP:0009825)1.74339437
103Aplasia involving bones of the upper limbs (HP:0009823)1.74339437
104Aplasia of the phalanges of the hand (HP:0009802)1.74339437
105Ependymoma (HP:0002888)1.74085505
106Anophthalmia (HP:0000528)1.73646604
107Cerebellar dysplasia (HP:0007033)1.73384762
108Impaired smooth pursuit (HP:0007772)1.73266822
109Hemorrhage of the eye (HP:0011885)1.72867258
110Glioma (HP:0009733)1.72717520
111Abnormality of the labia minora (HP:0012880)1.72661249
112Fibular aplasia (HP:0002990)1.72623760
113Postural instability (HP:0002172)1.71434254
114Anxiety (HP:0000739)1.71321841
115Autism (HP:0000717)1.71159723
116Oligodactyly (HP:0012165)1.71022699
117Generalized tonic-clonic seizures (HP:0002069)1.71018223
118Anal stenosis (HP:0002025)1.70721578
119Back pain (HP:0003418)1.68949078
120Transposition of the great arteries (HP:0001669)1.67200210
121Abnormal connection of the cardiac segments (HP:0011545)1.67200210
122Abnormal ventriculo-arterial connection (HP:0011563)1.67200210
123Hyperglycinuria (HP:0003108)1.67010042
124Abnormality of the nasal septum (HP:0000419)1.66332334
125Focal dystonia (HP:0004373)1.65091399
126Bowel incontinence (HP:0002607)1.64119224
127Chorioretinal atrophy (HP:0000533)1.64048634
128Morphological abnormality of the middle ear (HP:0008609)1.63829339
129Atonic seizures (HP:0010819)1.63713281
130Mutism (HP:0002300)1.63171201
131Specific learning disability (HP:0001328)1.63119609
132Hypophosphatemic rickets (HP:0004912)1.63017436
133Overriding aorta (HP:0002623)1.62565148
134Congenital malformation of the right heart (HP:0011723)1.62554802
135Double outlet right ventricle (HP:0001719)1.62554802
136Incomplete penetrance (HP:0003829)1.62017582
137Truncal obesity (HP:0001956)1.61532734
138Hyperacusis (HP:0010780)1.61363291
139Bradykinesia (HP:0002067)1.60814483
140Morphological abnormality of the pyramidal tract (HP:0002062)1.60720442
141Renal hypoplasia (HP:0000089)1.60307404
142Potter facies (HP:0002009)1.59731209
143Facial shape deformation (HP:0011334)1.59731209
144Scotoma (HP:0000575)1.59548045
145Shawl scrotum (HP:0000049)1.59083637
146Hypercholesterolemia (HP:0003124)1.58902480
147Restlessness (HP:0000711)1.57896141
148Acanthocytosis (HP:0001927)1.56495071
149Myelomeningocele (HP:0002475)1.55723021
150Supernumerary spleens (HP:0009799)1.55275142
151Type II lissencephaly (HP:0007260)1.54555872
152Vaginal atresia (HP:0000148)1.54383493
153Cortical dysplasia (HP:0002539)1.54125103
154Facial hemangioma (HP:0000329)1.53726288
155Hypolipoproteinemia (HP:0010981)1.53607682
156Renal dysplasia (HP:0000110)1.51755741
157Abnormality of carpal bone ossification (HP:0006257)1.50965110
158Pendular nystagmus (HP:0012043)1.49216135
159Genital tract atresia (HP:0001827)1.49144423
160Hypoplasia of the corpus callosum (HP:0002079)1.48444956
161Hyperglycinemia (HP:0002154)1.47701290
162Xanthomatosis (HP:0000991)1.45752568
163Widely patent fontanelles and sutures (HP:0004492)1.45687627

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.53168516
2NTRK33.17257121
3ICK2.78448898
4EPHA42.74128563
5AKT32.66085182
6PRKD32.54927138
7MAP3K92.53257489
8STK162.51394404
9NTRK22.47199738
10MAP3K42.41628504
11EPHA32.27907470
12KSR12.04189826
13MINK11.93404362
14TYRO31.83055922
15PAK61.75828800
16KSR21.66410453
17FGFR41.65701323
18WNK31.62458018
19PNCK1.59548861
20MAPK151.58168523
21SGK4941.51682083
22SGK2231.51682083
23MAPK131.46893696
24MAP2K71.44729438
25MAP3K21.41613028
26PHKG11.40236025
27PHKG21.40236025
28SGK21.36552138
29DAPK21.31407398
30DYRK1A1.26563701
31STK381.25290843
32CDK121.24486328
33CASK1.18499029
34NTRK11.18152425
35BRD41.16477587
36DYRK21.16317798
37CDK51.15196572
38FGFR31.13803596
39MAP4K21.12590029
40PKN21.12134000
41UHMK11.09752807
42SGK31.07954121
43CAMKK21.03180930
44BCR1.01933275
45FGFR21.01745501
46CSNK1G21.01412283
47CAMK1G1.00439046
48SIK20.96722327
49PIK3CA0.95489045
50STK390.95248112
51ERBB20.93545861
52TRIM280.92724063
53DYRK1B0.91017891
54LATS20.87865487
55PRKCG0.87189783
56MAP2K40.87170400
57ERBB30.87047924
58PINK10.84832045
59NEK10.83977932
60CSNK1A1L0.82797017
61CAMK40.82137217
62STK38L0.81409620
63PAK30.80828854
64LMTK20.80597192
65INSRR0.80248240
66CSNK1G30.80183582
67CAMKK10.76636347
68PRPF4B0.76483813
69BRAF0.75940518
70PRKAA10.73973081
71RET0.70587593
72PRKCZ0.70451574
73STK110.69918150
74TNIK0.67370749
75LATS10.65632336
76CAMK1D0.64758430
77CDK180.64344977
78RIPK10.64032788
79CDC42BPA0.63521884
80EPHB20.63036609
81RPS6KB10.62226096
82CAMK2A0.61000993
83CDK140.60892780
84CDK150.60627697
85PDGFRA0.60418400
86BRSK10.59329109
87CDC70.58506111
88CDK30.57888911
89WNK40.56078569
90SGK10.55089058
91CAMK2B0.54772591
92CSNK1G10.54341545
93CSNK1E0.54054469
94MAPK100.54045950
95ERBB40.53547837
96MARK20.53325748
97GSK3B0.52568301
98FGFR10.52082865
99CDK11A0.52008836
100WNK10.51545739
101RPS6KA30.50779729
102NEK20.49813492
103IRAK20.47958685
104PRKCE0.46943735
105CHEK20.46016267
106PLK20.45737228
107RPS6KA20.45735875
108EEF2K0.45500491
109FRK0.44870625
110SRPK10.42395872
111MAPK80.40980450
112CDK10.40864453
113MAPK90.40607781
114MTOR0.40599927
115CAMK10.39483674
116PRKACA0.39083106
117FER0.38863921
118SIK10.37672780
119DAPK10.37557129
120CSNK1D0.37249946
121PRKAA20.37030400
122MAP3K100.36810004
123PKN10.36463398

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.90748204
2Olfactory transduction_Homo sapiens_hsa047402.71543120
3Steroid biosynthesis_Homo sapiens_hsa001002.49849991
4Synaptic vesicle cycle_Homo sapiens_hsa047212.41258409
5GABAergic synapse_Homo sapiens_hsa047272.25938543
6Insulin secretion_Homo sapiens_hsa049112.21533552
7Circadian entrainment_Homo sapiens_hsa047132.21167131
8Glutamatergic synapse_Homo sapiens_hsa047242.20746799
9Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.13097193
10Phototransduction_Homo sapiens_hsa047442.12866068
11Long-term potentiation_Homo sapiens_hsa047202.03372757
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.01251915
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.98550907
14Fat digestion and absorption_Homo sapiens_hsa049751.94103623
15Amphetamine addiction_Homo sapiens_hsa050311.93257311
16Morphine addiction_Homo sapiens_hsa050321.91480578
17Dopaminergic synapse_Homo sapiens_hsa047281.90181275
18Cocaine addiction_Homo sapiens_hsa050301.87549912
19Vitamin digestion and absorption_Homo sapiens_hsa049771.72812700
20Cholinergic synapse_Homo sapiens_hsa047251.66494063
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.63318714
22Taste transduction_Homo sapiens_hsa047421.60870102
23Gap junction_Homo sapiens_hsa045401.58861860
24Axon guidance_Homo sapiens_hsa043601.57997986
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.56901219
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.55507929
27Type II diabetes mellitus_Homo sapiens_hsa049301.53950276
28Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.53170734
29Circadian rhythm_Homo sapiens_hsa047101.52833698
30Salivary secretion_Homo sapiens_hsa049701.47401602
31Dorso-ventral axis formation_Homo sapiens_hsa043201.47318519
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.39166934
33Complement and coagulation cascades_Homo sapiens_hsa046101.36125045
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.34842875
35Long-term depression_Homo sapiens_hsa047301.34537473
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.30744556
37Serotonergic synapse_Homo sapiens_hsa047261.30689640
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.27523173
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.26929867
40Renin secretion_Homo sapiens_hsa049241.24482340
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.22951535
42Gastric acid secretion_Homo sapiens_hsa049711.19188255
43Cyanoamino acid metabolism_Homo sapiens_hsa004601.18132283
44Endometrial cancer_Homo sapiens_hsa052131.17490867
45Oxytocin signaling pathway_Homo sapiens_hsa049211.17190213
46GnRH signaling pathway_Homo sapiens_hsa049121.16563811
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.16079063
48ErbB signaling pathway_Homo sapiens_hsa040121.15685947
49Oocyte meiosis_Homo sapiens_hsa041141.15497809
50Glioma_Homo sapiens_hsa052141.15347872
51Melanogenesis_Homo sapiens_hsa049161.12379794
52Fatty acid metabolism_Homo sapiens_hsa012121.09293039
53Fatty acid biosynthesis_Homo sapiens_hsa000611.09167950
54Sulfur relay system_Homo sapiens_hsa041221.08525334
55Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07236890
56Starch and sucrose metabolism_Homo sapiens_hsa005001.05217568
57Pentose and glucuronate interconversions_Homo sapiens_hsa000401.05132097
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.03593889
59Estrogen signaling pathway_Homo sapiens_hsa049151.02428066
60Nitrogen metabolism_Homo sapiens_hsa009101.02110459
61Hedgehog signaling pathway_Homo sapiens_hsa043401.01297015
62Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.00876348
63PPAR signaling pathway_Homo sapiens_hsa033201.00551536
64Thyroid hormone signaling pathway_Homo sapiens_hsa049191.00537130
65cAMP signaling pathway_Homo sapiens_hsa040241.00016681
66Histidine metabolism_Homo sapiens_hsa003400.98096125
67mTOR signaling pathway_Homo sapiens_hsa041500.97331171
68Calcium signaling pathway_Homo sapiens_hsa040200.96997470
69Alcoholism_Homo sapiens_hsa050340.95310123
70Wnt signaling pathway_Homo sapiens_hsa043100.91200746
71ABC transporters_Homo sapiens_hsa020100.89355191
72cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88191131
73Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86459808
74Hippo signaling pathway_Homo sapiens_hsa043900.85599214
75Butanoate metabolism_Homo sapiens_hsa006500.85207611
76Fatty acid degradation_Homo sapiens_hsa000710.84575470
77Choline metabolism in cancer_Homo sapiens_hsa052310.84566292
78Renal cell carcinoma_Homo sapiens_hsa052110.83284866
79Bile secretion_Homo sapiens_hsa049760.82941919
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.80730814
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80519343
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.80135317
83Basal cell carcinoma_Homo sapiens_hsa052170.79200568
84Arginine and proline metabolism_Homo sapiens_hsa003300.78043135
85Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77414457
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.76425034
87Propanoate metabolism_Homo sapiens_hsa006400.75423147
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73930974
89Cardiac muscle contraction_Homo sapiens_hsa042600.73049754
90Colorectal cancer_Homo sapiens_hsa052100.71219404
91Phenylalanine metabolism_Homo sapiens_hsa003600.70961869
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69981031
93Retinol metabolism_Homo sapiens_hsa008300.69397865
94Thyroid hormone synthesis_Homo sapiens_hsa049180.69314712
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.68326039
96Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.68303055
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68202783
98Tight junction_Homo sapiens_hsa045300.67858611
99Chemical carcinogenesis_Homo sapiens_hsa052040.67635316
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66877594
101Lysine degradation_Homo sapiens_hsa003100.66326687
102Inositol phosphate metabolism_Homo sapiens_hsa005620.65667954
103Insulin signaling pathway_Homo sapiens_hsa049100.64678586
104Glucagon signaling pathway_Homo sapiens_hsa049220.64595190
105Pancreatic secretion_Homo sapiens_hsa049720.62256574
106Non-small cell lung cancer_Homo sapiens_hsa052230.62219509
107Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61710428
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61588546
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60315115
110Ether lipid metabolism_Homo sapiens_hsa005650.60221370
111Peroxisome_Homo sapiens_hsa041460.59430056
112Vascular smooth muscle contraction_Homo sapiens_hsa042700.59323211
113Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58440252
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57952140
115mRNA surveillance pathway_Homo sapiens_hsa030150.57701487
116Sphingolipid metabolism_Homo sapiens_hsa006000.57591319
117Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.56796092
118Vibrio cholerae infection_Homo sapiens_hsa051100.55361857
119Mineral absorption_Homo sapiens_hsa049780.55261722
120Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.54178044
121beta-Alanine metabolism_Homo sapiens_hsa004100.54138412
122Tryptophan metabolism_Homo sapiens_hsa003800.53691716
123VEGF signaling pathway_Homo sapiens_hsa043700.53635476
124Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53263850
125Notch signaling pathway_Homo sapiens_hsa043300.52966559
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.52458077
127Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51121235
1282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50807778
129Glycerolipid metabolism_Homo sapiens_hsa005610.48244345
130Collecting duct acid secretion_Homo sapiens_hsa049660.48200520
131Sulfur metabolism_Homo sapiens_hsa009200.47455973
132Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45581442
133MAPK signaling pathway_Homo sapiens_hsa040100.45148147
134Central carbon metabolism in cancer_Homo sapiens_hsa052300.44937622
135Ovarian steroidogenesis_Homo sapiens_hsa049130.44293111
136Rap1 signaling pathway_Homo sapiens_hsa040150.41888718
137Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41749224
138Arginine biosynthesis_Homo sapiens_hsa002200.41703232
139AMPK signaling pathway_Homo sapiens_hsa041520.41011575
140Prion diseases_Homo sapiens_hsa050200.40009329
141Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39977702
142Ras signaling pathway_Homo sapiens_hsa040140.39519117

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