ZZZ3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)5.14816412
2nuclear pore complex assembly (GO:0051292)4.93127368
3nuclear pore organization (GO:0006999)4.55887225
4regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.19809486
5protein prenylation (GO:0018342)4.05198970
6prenylation (GO:0097354)4.05198970
7pore complex assembly (GO:0046931)4.04894320
8regulation of RNA export from nucleus (GO:0046831)3.86824452
9regulation of centrosome duplication (GO:0010824)3.62032696
10DNA damage induced protein phosphorylation (GO:0006975)3.56235982
11monoubiquitinated protein deubiquitination (GO:0035520)3.46451653
12cytoplasmic mRNA processing body assembly (GO:0033962)3.44786060
13regulation of centrosome cycle (GO:0046605)3.42996896
14microtubule anchoring (GO:0034453)3.37423318
15regulation of DNA endoreduplication (GO:0032875)3.32754165
16interkinetic nuclear migration (GO:0022027)3.31923594
17DNA unwinding involved in DNA replication (GO:0006268)3.31554585
18mitotic chromosome condensation (GO:0007076)3.30627211
19dosage compensation (GO:0007549)3.30025703
20non-recombinational repair (GO:0000726)3.29927093
21double-strand break repair via nonhomologous end joining (GO:0006303)3.29927093
22regulation of nucleobase-containing compound transport (GO:0032239)3.26713724
23protein localization to kinetochore (GO:0034501)3.25097293
24regulation of histone H3-K9 methylation (GO:0051570)3.20723213
25regulation of spindle organization (GO:0090224)3.20252905
26dorsal/ventral axis specification (GO:0009950)3.19286090
27ncRNA catabolic process (GO:0034661)3.17537447
28kinetochore organization (GO:0051383)3.13283368
29regulation of hexokinase activity (GO:1903299)3.11818902
30regulation of glucokinase activity (GO:0033131)3.11818902
31DNA duplex unwinding (GO:0032508)3.06976948
32replication fork processing (GO:0031297)3.06842374
33DNA geometric change (GO:0032392)3.06551081
34histone H2A monoubiquitination (GO:0035518)3.06255139
35mitotic nuclear envelope disassembly (GO:0007077)3.03489092
36CENP-A containing nucleosome assembly (GO:0034080)3.03015661
37positive regulation of mitotic sister chromatid separation (GO:1901970)2.99723730
38positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.99723730
39positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.99723730
40sister chromatid cohesion (GO:0007062)2.99696654
41ribonucleoprotein complex disassembly (GO:0032988)2.98983923
42peptidyl-lysine trimethylation (GO:0018023)2.98484972
43mitotic metaphase plate congression (GO:0007080)2.97015713
44negative regulation of DNA-dependent DNA replication (GO:2000104)2.96377170
45negative regulation of histone methylation (GO:0031061)2.95659029
46chromatin remodeling at centromere (GO:0031055)2.94774053
47glucocorticoid receptor signaling pathway (GO:0042921)2.91752735
48regulation of mitotic spindle organization (GO:0060236)2.91172980
49translesion synthesis (GO:0019985)2.89697230
50regulation of mitotic spindle checkpoint (GO:1903504)2.89188294
51regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.89188294
52embryonic foregut morphogenesis (GO:0048617)2.89153522
53nuclear envelope disassembly (GO:0051081)2.87506503
54membrane disassembly (GO:0030397)2.87506503
55metaphase plate congression (GO:0051310)2.86141712
56histone H3-K4 methylation (GO:0051568)2.83728368
57pre-miRNA processing (GO:0031054)2.82587739
58replicative senescence (GO:0090399)2.81275395
59chromatin assembly (GO:0031497)2.80711881
60telomere maintenance via telomerase (GO:0007004)2.79558261
61regulation of centriole replication (GO:0046599)2.79376009
62histone-serine phosphorylation (GO:0035404)2.78449309
63snRNA transcription (GO:0009301)2.78428146
64resolution of meiotic recombination intermediates (GO:0000712)2.77920542
65regulation of sister chromatid cohesion (GO:0007063)2.75802286
66DNA replication-dependent nucleosome assembly (GO:0006335)2.75784689
67DNA replication-dependent nucleosome organization (GO:0034723)2.75784689
68histone mRNA catabolic process (GO:0071044)2.75423616
69folic acid-containing compound biosynthetic process (GO:0009396)2.75244880
70protein localization to chromosome, centromeric region (GO:0071459)2.74556242
71negative regulation of DNA repair (GO:0045738)2.74440666
72nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.74147375
73rRNA catabolic process (GO:0016075)2.72988858
74pancreas development (GO:0031016)2.72769109
75sister chromatid segregation (GO:0000819)2.72452146
76positive regulation of chromosome segregation (GO:0051984)2.71504540
77regulation of helicase activity (GO:0051095)2.71430158
78RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.71001917
79corticosteroid receptor signaling pathway (GO:0031958)2.69562035
80regulation of mitotic metaphase/anaphase transition (GO:0030071)2.67806685
81postreplication repair (GO:0006301)2.66939815
82positive regulation of glycolytic process (GO:0045821)2.66695662
83histone H4-K12 acetylation (GO:0043983)2.65430075
84histone exchange (GO:0043486)2.62525290
85spindle assembly checkpoint (GO:0071173)2.61699393
86organ growth (GO:0035265)2.61576842
87regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.61060870
88DNA conformation change (GO:0071103)2.60989034
89alternative mRNA splicing, via spliceosome (GO:0000380)2.59974353
90spindle checkpoint (GO:0031577)2.59723662
91RNA-dependent DNA replication (GO:0006278)2.59089295
92protein K11-linked deubiquitination (GO:0035871)2.57901090
93positive regulation of DNA-templated transcription, initiation (GO:2000144)2.57601901
94double-strand break repair via homologous recombination (GO:0000724)2.57271356
95recombinational repair (GO:0000725)2.56444028
96IMP biosynthetic process (GO:0006188)2.56438244
97DNA replication checkpoint (GO:0000076)2.56040294
98histone H3-K9 methylation (GO:0051567)2.55940971
99histone H4-K16 acetylation (GO:0043984)2.55811859
100histone H3-K36 demethylation (GO:0070544)2.55698265
101mitotic spindle assembly checkpoint (GO:0007094)2.53258478
102regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.53145725
103ribosome assembly (GO:0042255)2.53006788
104histone H4-K8 acetylation (GO:0043982)2.51456250
105histone H4-K5 acetylation (GO:0043981)2.51456250
106DNA double-strand break processing (GO:0000729)2.51452512
107spindle assembly involved in mitosis (GO:0090307)2.51298277
108IMP metabolic process (GO:0046040)2.50491913
109negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.49970711
110negative regulation of sister chromatid segregation (GO:0033046)2.49970711
111negative regulation of mitotic sister chromatid separation (GO:2000816)2.49970711
112negative regulation of mitotic sister chromatid segregation (GO:0033048)2.49970711
113mitotic spindle checkpoint (GO:0071174)2.49936465
114histone lysine methylation (GO:0034968)2.49892290
115regulation of sister chromatid segregation (GO:0033045)2.49382437
116regulation of mitotic sister chromatid separation (GO:0010965)2.49382437
117regulation of mitotic sister chromatid segregation (GO:0033047)2.49382437
118DNA topological change (GO:0006265)2.49153845
119microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.49010298
120chromatin assembly or disassembly (GO:0006333)2.48871285
121DNA replication initiation (GO:0006270)2.48159337
122meiotic chromosome segregation (GO:0045132)2.47894756
123attachment of spindle microtubules to kinetochore (GO:0008608)2.47626428
124somatic diversification of immune receptors via somatic mutation (GO:0002566)2.47403365
125somatic hypermutation of immunoglobulin genes (GO:0016446)2.47403365
126negative regulation of chromosome segregation (GO:0051985)2.47016024
127positive regulation of histone H3-K4 methylation (GO:0051571)2.46340507
128protein localization to chromosome (GO:0034502)2.46194186
129gene silencing by RNA (GO:0031047)2.44740574
130mRNA stabilization (GO:0048255)2.43914620
131RNA stabilization (GO:0043489)2.43914620
132organelle disassembly (GO:1903008)2.43610116
133stress granule assembly (GO:0034063)2.43248410
134regulation of chromosome segregation (GO:0051983)2.42988685
135maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.42739555
136negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.42715426
137negative regulation of translation, ncRNA-mediated (GO:0040033)2.42715426
138regulation of translation, ncRNA-mediated (GO:0045974)2.42715426
139NLS-bearing protein import into nucleus (GO:0006607)2.42549032
140centrosome duplication (GO:0051298)2.42377544
141peptidyl-lysine dimethylation (GO:0018027)2.42225186
142negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.41765420
143definitive hemopoiesis (GO:0060216)2.41472664
144centriole replication (GO:0007099)2.40049223
145mitotic sister chromatid segregation (GO:0000070)2.39830939
146establishment of protein localization to Golgi (GO:0072600)2.37385068
147microtubule organizing center organization (GO:0031023)2.36726649
148neural tube formation (GO:0001841)2.36654147
149regulation of telomere maintenance via telomerase (GO:0032210)2.36489184
150gastrulation with mouth forming second (GO:0001702)2.36097516
151response to X-ray (GO:0010165)2.34976019
152genitalia morphogenesis (GO:0035112)2.33226193
153acrosome assembly (GO:0001675)2.31304353
154centrosome organization (GO:0051297)2.30766856
155maturation of 5.8S rRNA (GO:0000460)2.26387640
156regulation of telomere maintenance (GO:0032204)2.26273052

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.81950718
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.90961348
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.64199254
4SALL1_21062744_ChIP-ChIP_HESCs_Human4.13733820
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.65772287
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.59964676
7KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.38455801
8* POU3F2_20337985_ChIP-ChIP_501MEL_Human3.04139681
9FUS_26573619_Chip-Seq_HEK293_Human2.81804000
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.78131128
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.74830719
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.72803688
13AR_21909140_ChIP-Seq_LNCAP_Human2.64480142
14GBX2_23144817_ChIP-Seq_PC3_Human2.59877880
15E2F1_21310950_ChIP-Seq_MCF-7_Human2.50830864
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.43440708
17IGF1R_20145208_ChIP-Seq_DFB_Human2.29285828
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.27746210
19TAF15_26573619_Chip-Seq_HEK293_Human2.26153818
20ZNF274_21170338_ChIP-Seq_K562_Hela2.24852213
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.98619638
22MYC_22102868_ChIP-Seq_BL_Human1.95619973
23FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.91816988
24GATA1_22025678_ChIP-Seq_K562_Human1.88921179
25ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.85217057
26HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.85173335
27* MYC_18555785_ChIP-Seq_MESCs_Mouse1.84394638
28KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.83506989
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.80708090
30P300_19829295_ChIP-Seq_ESCs_Human1.78827400
31PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.74216446
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.70415833
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70142132
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.67063875
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.63975475
36* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.59422340
37MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.58394165
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.58344058
39SMAD4_21799915_ChIP-Seq_A2780_Human1.57779159
40ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.57642214
41TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.55199972
42GABP_17652178_ChIP-ChIP_JURKAT_Human1.53745491
43* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.50236460
44NELFA_20434984_ChIP-Seq_ESCs_Mouse1.49956815
45* STAT3_23295773_ChIP-Seq_U87_Human1.49188100
46GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.48562831
47RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48504867
48OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.48390955
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47554503
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.47012834
51MYC_19079543_ChIP-ChIP_MESCs_Mouse1.46526997
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.46103618
53ER_23166858_ChIP-Seq_MCF-7_Human1.45889296
54PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45742673
55* BRD4_25478319_ChIP-Seq_HGPS_Human1.45443612
56SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.38961535
57EST1_17652178_ChIP-ChIP_JURKAT_Human1.38218687
58* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.37973122
59* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37575496
60VDR_22108803_ChIP-Seq_LS180_Human1.37300590
61PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37253304
62MYC_18940864_ChIP-ChIP_HL60_Human1.37178835
63FOXM1_26456572_ChIP-Seq_MCF-7_Human1.35636010
64MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.34892130
65* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.32530815
66ELK1_19687146_ChIP-ChIP_HELA_Human1.31315475
67CBP_20019798_ChIP-Seq_JUKART_Human1.31055742
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31055742
69UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30685489
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.29144538
71IRF1_19129219_ChIP-ChIP_H3396_Human1.27666584
72* NOTCH1_21737748_ChIP-Seq_TLL_Human1.27211305
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.26354480
74FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.25965752
75SMAD_19615063_ChIP-ChIP_OVARY_Human1.25515223
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25295575
77EWS_26573619_Chip-Seq_HEK293_Human1.24110115
78* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23252940
79SCL_19346495_ChIP-Seq_HPC-7_Human1.23092113
80TCF4_23295773_ChIP-Seq_U87_Human1.20290468
81CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17814021
82MYC_19030024_ChIP-ChIP_MESCs_Mouse1.17428400
83* NANOG_18555785_Chip-Seq_ESCs_Mouse1.17388858
84MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15346521
85AR_25329375_ChIP-Seq_VCAP_Human1.14885780
86SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.14848459
87STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.14765571
88PKCTHETA_26484144_Chip-Seq_BREAST_Human1.13645232
89* TCF7_22412390_ChIP-Seq_EML_Mouse1.13474344
90SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13019206
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.12690434
92* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.11860424
93NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.10819734
94NRF2_20460467_ChIP-Seq_MEFs_Mouse1.10819734
95SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09943987
96SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.09724656
97SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.09724656
98CHD1_26751641_Chip-Seq_LNCaP_Human1.09009757
99CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08796900
100TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08739931
101GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08668324
102NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07697039
103SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.07473095
104ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07287266
105* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.06619194
106VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.06378612
107STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.05928738
108CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.05358320
109* E2F1_18555785_Chip-Seq_ESCs_Mouse1.05278019
110* RUNX2_22187159_ChIP-Seq_PCA_Human1.03984720
111FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.03602913
112CIITA_25753668_ChIP-Seq_RAJI_Human1.03563051
113* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.03162412
114NFE2_27457419_Chip-Seq_LIVER_Mouse1.02989584
115CDX2_22108803_ChIP-Seq_LS180_Human1.02951075
116* KDM5A_27292631_Chip-Seq_BREAST_Human1.02513717
117EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02026365
118CDX2_19796622_ChIP-Seq_MESCs_Mouse1.01828379
119TP53_16413492_ChIP-PET_HCT116_Human1.01759264
120NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.01445830
121* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.01067900
122TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.00908543
123JUN_21703547_ChIP-Seq_K562_Human1.00363995
124SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.99389882
125PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98896938
126* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.98507708
127STAT6_21828071_ChIP-Seq_BEAS2B_Human0.97766836
128FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.97693927
129* TCF4_22108803_ChIP-Seq_LS180_Human0.97411148
130KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97311667
131* P53_22387025_ChIP-Seq_ESCs_Mouse0.97148946
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.96820978
133MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.96107629
134CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.96053537
135POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.95426642
136* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.94471746
137CRX_20693478_ChIP-Seq_RETINA_Mouse0.94417070
138POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93309012
139CLOCK_20551151_ChIP-Seq_293T_Human0.92206639
140TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91927526
141MYB_26560356_Chip-Seq_TH1_Human0.91422234
142PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90459964
143* UBF1/2_26484160_Chip-Seq_HMECs_Human0.87646766
144TCF4_18268006_ChIP-ChIP_LS174T_Human0.87295907
145ERG_20887958_ChIP-Seq_HPC-7_Mouse0.85984132
146HIF1A_21447827_ChIP-Seq_MCF-7_Human0.85787588
147EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.84700718
148* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.84609689
149DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.84218658
150GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83479522
151* TFEB_21752829_ChIP-Seq_HELA_Human0.83308672
152* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.83274860
153CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.82965164
154SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.82383478
155BRD4_27068464_Chip-Seq_AML-cells_Mouse0.81851742
156VDR_23849224_ChIP-Seq_CD4+_Human0.81410025
157* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.80603761
158SOX2_18555785_ChIP-Seq_MESCs_Mouse0.78463580
159NFIB_24661679_ChIP-Seq_LUNG_Mouse0.77425707
160CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.77066147
161FOXO3_23340844_ChIP-Seq_DLD1_Human0.76701105
162SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.76628747
163MYB_26560356_Chip-Seq_TH2_Human0.75448818
164NANOG_21062744_ChIP-ChIP_HESCs_Human0.75103635
165TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.74768705
166SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.74396904
167* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.74175169
168* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.74171257
169* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.73808507

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.33550490
2MP0010094_abnormal_chromosome_stability2.81068329
3MP0008007_abnormal_cellular_replicative2.60966477
4MP0002102_abnormal_ear_morphology2.54672208
5MP0003111_abnormal_nucleus_morphology2.52343697
6MP0000569_abnormal_digit_pigmentation2.39181643
7MP0000372_irregular_coat_pigmentation2.38454870
8MP0010307_abnormal_tumor_latency2.36343726
9MP0008058_abnormal_DNA_repair2.29146602
10MP0010352_gastrointestinal_tract_polyps2.26765334
11MP0003077_abnormal_cell_cycle2.23868758
12MP0003693_abnormal_embryo_hatching2.15407191
13MP0002877_abnormal_melanocyte_morpholog2.15036527
14MP0005171_absent_coat_pigmentation2.11718499
15MP0002396_abnormal_hematopoietic_system2.08654937
16MP0006054_spinal_hemorrhage2.00231477
17MP0009697_abnormal_copulation1.96707700
18MP0004808_abnormal_hematopoietic_stem1.94540308
19MP0000013_abnormal_adipose_tissue1.88986654
20MP0006072_abnormal_retinal_apoptosis1.88081297
21MP0003300_gastrointestinal_ulcer1.87748434
22MP0005076_abnormal_cell_differentiation1.84342689
23MP0000383_abnormal_hair_follicle1.74336828
24MP0003121_genomic_imprinting1.74332401
25MP0003937_abnormal_limbs/digits/tail_de1.68089210
26MP0003123_paternal_imprinting1.67923458
27MP0004957_abnormal_blastocyst_morpholog1.67159932
28MP0001661_extended_life_span1.64533179
29MP0000350_abnormal_cell_proliferation1.63205572
30MP0010678_abnormal_skin_adnexa1.61253529
31MP0003705_abnormal_hypodermis_morpholog1.58566193
32MP0005253_abnormal_eye_physiology1.54494504
33MP0000647_abnormal_sebaceous_gland1.53052889
34MP0000428_abnormal_craniofacial_morphol1.50285930
35MP0002095_abnormal_skin_pigmentation1.48746877
36MP0010030_abnormal_orbit_morphology1.48746875
37MP0000537_abnormal_urethra_morphology1.47439347
38MP0003890_abnormal_embryonic-extraembry1.46866020
39MP0004197_abnormal_fetal_growth/weight/1.45225659
40MP0005380_embryogenesis_phenotype1.43988972
41MP0001672_abnormal_embryogenesis/_devel1.43988972
42MP0003787_abnormal_imprinting1.42899245
43MP0005503_abnormal_tendon_morphology1.41976140
44MP0005408_hypopigmentation1.40021714
45MP0003984_embryonic_growth_retardation1.40006039
46MP0002084_abnormal_developmental_patter1.39153780
47MP0002088_abnormal_embryonic_growth/wei1.39006881
48MP0000733_abnormal_muscle_development1.38819785
49MP0002938_white_spotting1.37298085
50MP0003567_abnormal_fetal_cardiomyocyte1.36273420
51MP0008438_abnormal_cutaneous_collagen1.35979969
52MP0003786_premature_aging1.35856991
53MP0002086_abnormal_extraembryonic_tissu1.33206680
54MP0005075_abnormal_melanosome_morpholog1.32583561
55MP0005187_abnormal_penis_morphology1.31832332
56MP0004133_heterotaxia1.30147134
57MP0008877_abnormal_DNA_methylation1.29039694
58MP0005174_abnormal_tail_pigmentation1.26992775
59MP0003935_abnormal_craniofacial_develop1.26114389
60MP0008995_early_reproductive_senescence1.25223406
61MP0006276_abnormal_autonomic_nervous1.24381466
62MP0003950_abnormal_plasma_membrane1.23407292
63MP0009384_cardiac_valve_regurgitation1.23299142
64MP0001299_abnormal_eye_distance/1.22552103
65MP0002233_abnormal_nose_morphology1.21901317
66MP0002085_abnormal_embryonic_tissue1.20792358
67MP0003566_abnormal_cell_adhesion1.20765464
68MP0009703_decreased_birth_body1.19732837
69MP0001697_abnormal_embryo_size1.19074786
70MP0000015_abnormal_ear_pigmentation1.17692232
71MP0002697_abnormal_eye_size1.14942993
72MP0001730_embryonic_growth_arrest1.14487253
73MP0004264_abnormal_extraembryonic_tissu1.14171417
74MP0005220_abnormal_exocrine_pancreas1.13917736
75MP0003115_abnormal_respiratory_system1.13816642
76MP0002160_abnormal_reproductive_system1.13093990
77MP0001324_abnormal_eye_pigmentation1.12369692
78MP0001286_abnormal_eye_development1.11255801
79MP0005391_vision/eye_phenotype1.11214289
80MP0001849_ear_inflammation1.08514333
81MP0003941_abnormal_skin_development1.06415099
82MP0005551_abnormal_eye_electrophysiolog1.06081287
83MP0002638_abnormal_pupillary_reflex1.05903652
84MP0002234_abnormal_pharynx_morphology1.04613526
85MP0001293_anophthalmia1.03976989
86MP0002092_abnormal_eye_morphology1.03837362
87MP0000432_abnormal_head_morphology1.02706375
88MP0002928_abnormal_bile_duct1.02653788
89MP0000371_diluted_coat_color1.01703237
90MP0001879_abnormal_lymphatic_vessel1.01443115
91MP0003385_abnormal_body_wall1.01361519
92MP0009780_abnormal_chondrocyte_physiolo1.00907492
93MP0010234_abnormal_vibrissa_follicle1.00261229
94MP0002009_preneoplasia0.99898939
95MP0000631_abnormal_neuroendocrine_gland0.98832077
96MP0002925_abnormal_cardiovascular_devel0.97846051
97MP0000465_gastrointestinal_hemorrhage0.97174377
98MP0003718_maternal_effect0.97060148
99MP0009672_abnormal_birth_weight0.96660158
100MP0005023_abnormal_wound_healing0.96083773
101MP0002080_prenatal_lethality0.95226047
102MP0009053_abnormal_anal_canal0.95054495
103MP0005508_abnormal_skeleton_morphology0.94547515
104MP0003755_abnormal_palate_morphology0.94247521
105MP0002111_abnormal_tail_morphology0.93300544
106MP0003943_abnormal_hepatobiliary_system0.93037885
107MP0003045_fibrosis0.91147756
108MP0002075_abnormal_coat/hair_pigmentati0.90863361
109MP0001958_emphysema0.90015264
110MP0002163_abnormal_gland_morphology0.88286232
111MP0006292_abnormal_olfactory_placode0.88243876
112MP0002837_dystrophic_cardiac_calcinosis0.86768069
113MP0004215_abnormal_myocardial_fiber0.86584483
114MP0010368_abnormal_lymphatic_system0.86560783
115MP0000313_abnormal_cell_death0.84989767
116MP0003136_yellow_coat_color0.84496595
117MP0005397_hematopoietic_system_phenotyp0.83858182
118MP0001545_abnormal_hematopoietic_system0.83858182
119MP0002090_abnormal_vision0.83711822
120MP0000490_abnormal_crypts_of0.83649029
121MP0003221_abnormal_cardiomyocyte_apopto0.83378077
122MP0008932_abnormal_embryonic_tissue0.82546814
123MP0002166_altered_tumor_susceptibility0.82478277
124MP0000427_abnormal_hair_cycle0.81873852
125MP0009250_abnormal_appendicular_skeleto0.81400867
126MP0002109_abnormal_limb_morphology0.80767610
127MP0001915_intracranial_hemorrhage0.80694182
128MP0004272_abnormal_basement_membrane0.80284616
129MP0001929_abnormal_gametogenesis0.79304086
130MP0005379_endocrine/exocrine_gland_phen0.79161213
131MP0001186_pigmentation_phenotype0.79102938
132MP0005367_renal/urinary_system_phenotyp0.79042050
133MP0000516_abnormal_urinary_system0.79042050
134MP0008775_abnormal_heart_ventricle0.79011717
135MP0003828_pulmonary_edema0.78526088
136MP0000767_abnormal_smooth_muscle0.78356032
137MP0002177_abnormal_outer_ear0.77893821
138MP0000613_abnormal_salivary_gland0.77056507
139MP0003091_abnormal_cell_migration0.76698451
140MP0003942_abnormal_urinary_system0.76422892
141MP0002060_abnormal_skin_morphology0.75771262
142MP0000703_abnormal_thymus_morphology0.75522330
143MP0002932_abnormal_joint_morphology0.74985576
144MP0005195_abnormal_posterior_eye0.72478355
145MP0005266_abnormal_metabolism0.71490224
146MP0003119_abnormal_digestive_system0.70761578
147MP0000462_abnormal_digestive_system0.70399894
148MP0005248_abnormal_Harderian_gland0.68974626
149MP0000778_abnormal_nervous_system0.68824483

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)3.61072660
2Blue irides (HP:0000635)2.81931973
3Volvulus (HP:0002580)2.80985846
4Chronic hepatic failure (HP:0100626)2.79878524
5Chromsome breakage (HP:0040012)2.76663953
6Renal cortical cysts (HP:0000803)2.69727902
7Chromosomal breakage induced by crosslinking agents (HP:0003221)2.68185242
8Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.64996714
9Short 4th metacarpal (HP:0010044)2.64996714
10Thyroid carcinoma (HP:0002890)2.64702181
11Fair hair (HP:0002286)2.57823532
12Colon cancer (HP:0003003)2.46986830
13Lip pit (HP:0100267)2.46673395
14Neoplasm of the adrenal cortex (HP:0100641)2.45637650
15Cerebellar dysplasia (HP:0007033)2.44067063
16Absent frontal sinuses (HP:0002688)2.41255356
17Urethral obstruction (HP:0000796)2.38706481
18Hematochezia (HP:0002573)2.37222143
19Abnormality of the renal cortex (HP:0011035)2.30237486
20Generalized hypopigmentation of hair (HP:0011358)2.28765955
21Acute myeloid leukemia (HP:0004808)2.25123270
22Shallow orbits (HP:0000586)2.24057294
23Subacute progressive viral hepatitis (HP:0006572)2.22066213
24Ectopic kidney (HP:0000086)2.20728445
25Gastrointestinal atresia (HP:0002589)2.20457263
26Long eyelashes (HP:0000527)2.20316556
27Broad thumb (HP:0011304)2.20061832
28Abnormality of methionine metabolism (HP:0010901)2.17614866
29Intestinal atresia (HP:0011100)2.16735012
30Cervical subluxation (HP:0003308)2.15357142
31Hyperventilation (HP:0002883)2.13804477
32Spinal cord lesions (HP:0100561)2.12745956
33Syringomyelia (HP:0003396)2.12745956
34Freckling (HP:0001480)2.11986881
35Medial flaring of the eyebrow (HP:0010747)2.11082184
36Narrow palate (HP:0000189)2.10859994
37Tubulointerstitial nephritis (HP:0001970)2.09652976
38Macroorchidism (HP:0000053)2.06769571
39Congenital primary aphakia (HP:0007707)2.05462188
40Abnormality of the nasal septum (HP:0000419)2.00859196
41Pancreatic cysts (HP:0001737)1.99146048
42Aortic aneurysm (HP:0004942)1.98005748
43Abnormality of chromosome stability (HP:0003220)1.97815234
44Prominent nose (HP:0000448)1.97502778
45Abnormality of the ileum (HP:0001549)1.97442445
46Poor coordination (HP:0002370)1.96645476
47Viral hepatitis (HP:0006562)1.96602877
48Abnormality of midbrain morphology (HP:0002418)1.95990730
49Molar tooth sign on MRI (HP:0002419)1.95990730
50Spondylolisthesis (HP:0003302)1.95197541
51Rhabdomyosarcoma (HP:0002859)1.95056900
52Abnormal auditory evoked potentials (HP:0006958)1.94866839
53Deep philtrum (HP:0002002)1.94853915
54Facial hemangioma (HP:0000329)1.94820263
55Nephroblastoma (Wilms tumor) (HP:0002667)1.94132091
56Esophageal atresia (HP:0002032)1.93587804
57Abnormality of the preputium (HP:0100587)1.93321517
58Biliary tract neoplasm (HP:0100574)1.92561016
59Increased nuchal translucency (HP:0010880)1.92165647
60Heterotopia (HP:0002282)1.90627430
61Thoracolumbar scoliosis (HP:0002944)1.90295048
62Methylmalonic acidemia (HP:0002912)1.89095290
63Curly hair (HP:0002212)1.88669144
64Nephrogenic diabetes insipidus (HP:0009806)1.87997155
65Meckel diverticulum (HP:0002245)1.87705323
66Hip dysplasia (HP:0001385)1.87574043
67Birth length less than 3rd percentile (HP:0003561)1.87516849
68High pitched voice (HP:0001620)1.87086430
69Small intestinal stenosis (HP:0012848)1.86785509
70Duodenal stenosis (HP:0100867)1.86785509
71Gait imbalance (HP:0002141)1.86764774
72Genital tract atresia (HP:0001827)1.85844185
73Sparse lateral eyebrow (HP:0005338)1.85555446
74Sloping forehead (HP:0000340)1.85016641
75Cerebral aneurysm (HP:0004944)1.83900697
76Homocystinuria (HP:0002156)1.83515940
77Abnormality of homocysteine metabolism (HP:0010919)1.83515940
78Vaginal atresia (HP:0000148)1.83330210
79Pancreatic fibrosis (HP:0100732)1.82574949
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82137327
81Abnormality of alanine metabolism (HP:0010916)1.82137327
82Hyperalaninemia (HP:0003348)1.82137327
83Broad phalanges of the hand (HP:0009768)1.81428426
84Abnormality of the renal medulla (HP:0100957)1.80982344
85Pheochromocytoma (HP:0002666)1.80331618
86Broad face (HP:0000283)1.79834793
87Long clavicles (HP:0000890)1.79693529
88Embryonal renal neoplasm (HP:0011794)1.79688763
89Abnormality of the 4th metacarpal (HP:0010012)1.79473816
90Aplasia/Hypoplasia of the tibia (HP:0005772)1.79426177
91Patchy hypopigmentation of hair (HP:0011365)1.79417179
92Medulloblastoma (HP:0002885)1.79220022
93Hypoplasia of the fovea (HP:0007750)1.78705378
94Aplasia/Hypoplasia of the fovea (HP:0008060)1.78705378
95Aortic regurgitation (HP:0001659)1.78464525
96Hypoplastic ischia (HP:0003175)1.78434261
97Deviation of the thumb (HP:0009603)1.78127919
98Nephronophthisis (HP:0000090)1.78027605
99Mitral valve prolapse (HP:0001634)1.78013715
100White forelock (HP:0002211)1.77462253
101Hypopigmentation of the fundus (HP:0007894)1.77422787
102Hypoplastic labia majora (HP:0000059)1.77132855
103Mesomelia (HP:0003027)1.76321927
104Astigmatism (HP:0000483)1.75884514
105Hypoglycemic seizures (HP:0002173)1.75714004
106Drooling (HP:0002307)1.74751877
107Abnormality of the fovea (HP:0000493)1.74715280
108Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.74356222
109Ankle contracture (HP:0006466)1.73751500
110Pancreatic islet-cell hyperplasia (HP:0004510)1.73516589
111Limited elbow extension (HP:0001377)1.73060409
112Asymmetry of the thorax (HP:0001555)1.72568003
113Broad phalanx (HP:0006009)1.72250917
114Anal stenosis (HP:0002025)1.71680574
115Abnormality of the duodenum (HP:0002246)1.71100165
116True hermaphroditism (HP:0010459)1.70834140
117Abnormality of the pancreatic islet cells (HP:0006476)1.70724488
118Abnormality of endocrine pancreas physiology (HP:0012093)1.70724488
119Myelodysplasia (HP:0002863)1.69620220
120Ependymoma (HP:0002888)1.69460243
121Hepatoblastoma (HP:0002884)1.68844700
122Abnormality of the pons (HP:0007361)1.68765243
123Osteolytic defects of the hand bones (HP:0009699)1.68042997
124Osteolytic defects of the phalanges of the hand (HP:0009771)1.68042997
125Gastrointestinal carcinoma (HP:0002672)1.67463122
126Malignant gastrointestinal tract tumors (HP:0006749)1.67463122
127Hypothermia (HP:0002045)1.67374743
128Neoplasm of the oral cavity (HP:0100649)1.67212492
129Hypoplasia of the maxilla (HP:0000327)1.66324790
130Proximal placement of thumb (HP:0009623)1.65809725
131Broad palm (HP:0001169)1.65798796
132Atrophic scars (HP:0001075)1.65208029
133Glioma (HP:0009733)1.65029383
134Premature rupture of membranes (HP:0001788)1.64758960
135Abnormality of the phalanges of the hallux (HP:0010057)1.64454612
136Chorioretinal atrophy (HP:0000533)1.64066237
137Progressive inability to walk (HP:0002505)1.63640943
138Abnormal biliary tract physiology (HP:0012439)1.63506897
139Bile duct proliferation (HP:0001408)1.63506897
140Termporal pattern (HP:0011008)1.63243037
141Insidious onset (HP:0003587)1.63243037
142Genu recurvatum (HP:0002816)1.63097715
143Papillary thyroid carcinoma (HP:0002895)1.62822693
144Broad long bones (HP:0005622)1.62807402
145Broad finger (HP:0001500)1.61739002
146Abnormality of the distal phalanx of the thumb (HP:0009617)1.61492511
147Protruding tongue (HP:0010808)1.60857947
148Bifid tongue (HP:0010297)1.60222267
149Clubbing of toes (HP:0100760)1.60070546
150Rectal prolapse (HP:0002035)1.59990473
151Neoplasm of the adrenal gland (HP:0100631)1.59888408
152Menstrual irregularities (HP:0000858)1.59297416
153Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.59091022
154Degeneration of the lateral corticospinal tracts (HP:0002314)1.58118430
155Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.58118430
156Partial agenesis of the corpus callosum (HP:0001338)1.57931440
157Abnormality of the vitamin B12 metabolism (HP:0004341)1.57854984
158Low anterior hairline (HP:0000294)1.57729955
159Abnormality of the labia majora (HP:0012881)1.56991426
160Astrocytoma (HP:0009592)1.56933984
161Abnormality of the astrocytes (HP:0100707)1.56933984
162Microtia (HP:0008551)1.56922052
163Disproportionate tall stature (HP:0001519)1.56602017
164Sandal gap (HP:0001852)1.56546301
165Neoplasm of the pancreas (HP:0002894)1.53574333
166Arterial tortuosity (HP:0005116)1.52970070
167Bicuspid aortic valve (HP:0001647)1.52093503
168Entropion (HP:0000621)1.51863889
169Dislocated radial head (HP:0003083)1.51264274
170Posterior subcapsular cataract (HP:0007787)1.51136303
171Aplasia/Hypoplasia of the uvula (HP:0010293)1.50659048
172Truncal obesity (HP:0001956)1.50580106
173Short middle phalanx of the 5th finger (HP:0004220)1.50486865
174Renal duplication (HP:0000075)1.49989839
175Thick eyebrow (HP:0000574)1.49148112
176Aortic dissection (HP:0002647)1.48818079
177Overlapping toe (HP:0001845)1.48627644
178Midline defect of the nose (HP:0004122)1.47687321
179Abnormality of the carotid arteries (HP:0005344)1.47516514
180Abnormality of the ischium (HP:0003174)1.47044744
181Hypospadias (HP:0000047)1.46995371

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.47202785
2LATS13.45065190
3CDK122.86552780
4RPS6KA42.78021606
5BMPR1B2.58173966
6EEF2K2.55365539
7NEK22.35860853
8TRIM282.31443382
9SCYL22.16150914
10MAP3K42.09403199
11BCR2.06673208
12PASK2.04365142
13TGFBR12.02156436
14STK31.96464929
15SRPK11.94653156
16MAP4K21.90736153
17BRD41.90358655
18TLK11.88136656
19TGFBR21.87850307
20FRK1.84571435
21BRSK21.83689974
22AKT31.81207515
23TAOK21.75061269
24WNK31.68302402
25PDK21.65974620
26ZAK1.65124618
27TTK1.60363295
28PBK1.57621524
29NUAK11.56454838
30WEE11.56425192
31ATR1.55842031
32MAP2K31.51259700
33RPS6KB21.50228598
34MAP2K71.46829277
35FGFR21.45798421
36DYRK31.44989587
37MKNK11.44843838
38CDK31.41816546
39STK101.34564651
40STK391.32676140
41PNCK1.30372270
42CSNK1G11.27504738
43CDK91.26954832
44ACVR1B1.25763443
45NLK1.24730736
46MAP3K101.23509291
47PDGFRA1.20619154
48CAMK1D1.19667432
49NEK11.19579898
50MTOR1.17469310
51NEK91.17191930
52CHEK11.17119095
53AURKB1.16516273
54MAP2K61.15547582
55CDK61.14250395
56MAP3K61.13274047
57MAP3K51.11495272
58ATM1.11209560
59CHEK21.10698735
60MELK1.10427453
61MKNK21.09444174
62TAF11.08880155
63TRPM71.08827954
64RIPK11.08614703
65PLK11.08271304
66EIF2AK31.05944743
67CDK41.03168782
68PLK30.97141013
69CSNK1G30.95268700
70CDK70.93784718
71PDGFRB0.92995016
72CASK0.90162709
73STK40.88886697
74FER0.88508264
75PKN20.87581830
76TTN0.87376054
77MAP3K80.87012639
78CAMKK20.86654219
79FGFR30.86470541
80WNK40.85908201
81DDR20.85485119
82VRK10.84728553
83NME20.83051478
84SIK10.82322490
85MET0.81087499
86PAK20.80856706
87CDK20.79430501
88STK240.79140276
89FLT30.79122631
90PLK20.78885888
91INSRR0.78770614
92CHUK0.78734074
93MST1R0.77257453
94PTK60.76687399
95ERBB30.75294647
96CSNK1G20.74591718
97DMPK0.73821629
98CLK10.73602230
99HIPK20.73587888
100BMPR20.73131659
101BUB10.72565472
102CDK10.72532618
103JAK30.71772060
104TSSK60.69585589
105EPHA20.69485946
106EIF2AK20.67769987
107EIF2AK10.67429913
108CDK80.66646959
109ALK0.65266898
110MAPK70.60531524
111PLK40.60207879
112MAP3K20.60114192
113MST40.59861904
114TEC0.59655834
115MARK30.58084059
116SGK20.57399641
117MAPK140.56577461
118SGK30.55636258
119PRKDC0.55342054
120PRKCE0.55138559
121PRKAA20.53691589
122OXSR10.52855892
123RPS6KA50.51730676
124PAK30.50996909
125PIK3CA0.50721802
126TNIK0.50023322
127FGFR10.49647429
128CSNK1A1L0.49516041
129CSNK1D0.49390836
130STK38L0.49297755
131CAMK1G0.49000869
132ERBB40.48147904
133PRKAA10.47716873
134MAP3K30.45474261
135MAPK130.45237065
136NEK60.45175209
137MAPK100.44730521
138ADRBK20.44156800
139GRK10.43766033
140MAPK10.43313220
141YES10.41073151
142ERBB20.40571244
143AKT10.39921353
144BRSK10.37806152
145MAP2K40.35973855
146MAPKAPK50.35831449

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.51798590
2Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.48912499
3DNA replication_Homo sapiens_hsa030302.42585940
4Cell cycle_Homo sapiens_hsa041102.27757572
5Mismatch repair_Homo sapiens_hsa034302.16688002
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.07740011
7Butanoate metabolism_Homo sapiens_hsa006502.06091255
8Propanoate metabolism_Homo sapiens_hsa006402.03350141
9Non-homologous end-joining_Homo sapiens_hsa034501.94379989
10Protein export_Homo sapiens_hsa030601.88585325
11RNA transport_Homo sapiens_hsa030131.87020595
12One carbon pool by folate_Homo sapiens_hsa006701.79529818
13Fanconi anemia pathway_Homo sapiens_hsa034601.77272465
14Base excision repair_Homo sapiens_hsa034101.73995652
15MicroRNAs in cancer_Homo sapiens_hsa052061.67373175
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.63392024
17Spliceosome_Homo sapiens_hsa030401.60887969
18Lysine degradation_Homo sapiens_hsa003101.60056791
19mRNA surveillance pathway_Homo sapiens_hsa030151.59125505
20Small cell lung cancer_Homo sapiens_hsa052221.58457630
21Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.58105761
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56151059
23Nucleotide excision repair_Homo sapiens_hsa034201.55793015
24Homologous recombination_Homo sapiens_hsa034401.53912860
25RNA degradation_Homo sapiens_hsa030181.53099436
26Regulation of autophagy_Homo sapiens_hsa041401.49342637
27Basal transcription factors_Homo sapiens_hsa030221.49297078
28Chronic myeloid leukemia_Homo sapiens_hsa052201.48855745
29Adherens junction_Homo sapiens_hsa045201.45046417
30Prostate cancer_Homo sapiens_hsa052151.39734180
31Transcriptional misregulation in cancer_Homo sapiens_hsa052021.38735690
32TGF-beta signaling pathway_Homo sapiens_hsa043501.38568711
33Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.37560931
34ECM-receptor interaction_Homo sapiens_hsa045121.36463394
35p53 signaling pathway_Homo sapiens_hsa041151.35630496
36Viral carcinogenesis_Homo sapiens_hsa052031.35150052
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.33106632
38Systemic lupus erythematosus_Homo sapiens_hsa053221.32089837
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.27755361
40HTLV-I infection_Homo sapiens_hsa051661.26857121
41Hippo signaling pathway_Homo sapiens_hsa043901.26211752
42Nitrogen metabolism_Homo sapiens_hsa009101.24684879
43Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.20033015
44Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.18292017
45Purine metabolism_Homo sapiens_hsa002301.17925043
46Herpes simplex infection_Homo sapiens_hsa051681.17292529
47Pancreatic cancer_Homo sapiens_hsa052121.14648551
48Antigen processing and presentation_Homo sapiens_hsa046121.14445235
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10729359
50Cysteine and methionine metabolism_Homo sapiens_hsa002701.10676787
51Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.10567050
52Vitamin B6 metabolism_Homo sapiens_hsa007501.09582994
53Non-small cell lung cancer_Homo sapiens_hsa052231.09454852
54Thyroid cancer_Homo sapiens_hsa052161.08965406
55Focal adhesion_Homo sapiens_hsa045101.07598578
56Endometrial cancer_Homo sapiens_hsa052131.07497003
57Basal cell carcinoma_Homo sapiens_hsa052171.06663053
58Proteoglycans in cancer_Homo sapiens_hsa052051.06548125
59Steroid biosynthesis_Homo sapiens_hsa001001.04433028
60Selenocompound metabolism_Homo sapiens_hsa004501.02993584
61Colorectal cancer_Homo sapiens_hsa052101.02624286
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.01541619
63FoxO signaling pathway_Homo sapiens_hsa040680.99953336
64NF-kappa B signaling pathway_Homo sapiens_hsa040640.96460216
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.91058294
66Hepatitis B_Homo sapiens_hsa051610.90702163
67mTOR signaling pathway_Homo sapiens_hsa041500.87054971
68Pathways in cancer_Homo sapiens_hsa052000.85919504
69Thyroid hormone signaling pathway_Homo sapiens_hsa049190.85186262
70Primary bile acid biosynthesis_Homo sapiens_hsa001200.84089277
71Platelet activation_Homo sapiens_hsa046110.84005148
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79789898
73PI3K-Akt signaling pathway_Homo sapiens_hsa041510.79554349
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.79062972
75Alcoholism_Homo sapiens_hsa050340.78974235
76Dorso-ventral axis formation_Homo sapiens_hsa043200.77600951
77Inositol phosphate metabolism_Homo sapiens_hsa005620.77104718
78Epstein-Barr virus infection_Homo sapiens_hsa051690.76303172
79Leukocyte transendothelial migration_Homo sapiens_hsa046700.75648708
80RNA polymerase_Homo sapiens_hsa030200.73496008
81Wnt signaling pathway_Homo sapiens_hsa043100.72464720
82Glioma_Homo sapiens_hsa052140.71598055
83Prolactin signaling pathway_Homo sapiens_hsa049170.71140785
84Circadian rhythm_Homo sapiens_hsa047100.70570615
85Bladder cancer_Homo sapiens_hsa052190.70365090
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.70055476
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.69819525
88Melanoma_Homo sapiens_hsa052180.68711400
89Apoptosis_Homo sapiens_hsa042100.67791514
90Ether lipid metabolism_Homo sapiens_hsa005650.66645256
91Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.66245176
92Phototransduction_Homo sapiens_hsa047440.66242686
93Measles_Homo sapiens_hsa051620.65915536
94Toxoplasmosis_Homo sapiens_hsa051450.65577890
95TNF signaling pathway_Homo sapiens_hsa046680.65575115
96Hedgehog signaling pathway_Homo sapiens_hsa043400.64788117
97Oocyte meiosis_Homo sapiens_hsa041140.64629091
98Acute myeloid leukemia_Homo sapiens_hsa052210.64181259
99Osteoclast differentiation_Homo sapiens_hsa043800.62907415
100Tight junction_Homo sapiens_hsa045300.62730932
101Notch signaling pathway_Homo sapiens_hsa043300.62643851
102Protein digestion and absorption_Homo sapiens_hsa049740.61714512
103B cell receptor signaling pathway_Homo sapiens_hsa046620.60692713
104Pyrimidine metabolism_Homo sapiens_hsa002400.59219848
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.58620297
106Jak-STAT signaling pathway_Homo sapiens_hsa046300.57155478
107Influenza A_Homo sapiens_hsa051640.57007411
108Hematopoietic cell lineage_Homo sapiens_hsa046400.55053471
109Pyruvate metabolism_Homo sapiens_hsa006200.54774542
110Renal cell carcinoma_Homo sapiens_hsa052110.54365863
111Taste transduction_Homo sapiens_hsa047420.54284091
112T cell receptor signaling pathway_Homo sapiens_hsa046600.54128207
113Insulin resistance_Homo sapiens_hsa049310.53533217
114Neurotrophin signaling pathway_Homo sapiens_hsa047220.53481801
115Sphingolipid metabolism_Homo sapiens_hsa006000.53302116
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52615196
117beta-Alanine metabolism_Homo sapiens_hsa004100.50518562
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48995954
119Hepatitis C_Homo sapiens_hsa051600.48835957
120Linoleic acid metabolism_Homo sapiens_hsa005910.48530018
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.48495619
122Steroid hormone biosynthesis_Homo sapiens_hsa001400.48036149
123Tryptophan metabolism_Homo sapiens_hsa003800.47852497
124Glycosaminoglycan degradation_Homo sapiens_hsa005310.46758535
125N-Glycan biosynthesis_Homo sapiens_hsa005100.46614502
126Rap1 signaling pathway_Homo sapiens_hsa040150.46496457
127MAPK signaling pathway_Homo sapiens_hsa040100.46469644
128Olfactory transduction_Homo sapiens_hsa047400.44957276
129Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44916178
130Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44277480
131ABC transporters_Homo sapiens_hsa020100.42036745
132Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.41268241
133Peroxisome_Homo sapiens_hsa041460.40908725
134Metabolic pathways_Homo sapiens_hsa011000.36538635
135Glucagon signaling pathway_Homo sapiens_hsa049220.36238597
136Type II diabetes mellitus_Homo sapiens_hsa049300.36027137
137Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.35921422
138AMPK signaling pathway_Homo sapiens_hsa041520.29911409
139Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.29288810
140Fatty acid metabolism_Homo sapiens_hsa012120.27707890
141Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.26276009
142Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.25370008
143Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24448152
144Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.23139610
145Arginine biosynthesis_Homo sapiens_hsa002200.22445352

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