COVID19-E protein host PPI from Krogan COVID19-E protein host PPI from Krogan AP3B1 CWC27 ZC3H18 BRD2 BRD4 SLC44A2 COVID19-M protein host PPI from Krogan COVID19-M protein host PPI from Krogan RTN4 TARS2 FAM8A1 PSMD8 SLC25A21 ETFA TUBGCP2 ACADM SAAL1 ATP6V1A TUBGCP3 YIF1A SLC30A9 COQ8B PITRM1 FASTKD5 BZW2 PMPCA GGCX ATP1B1 AASS REEP5 SLC30A7 INTS4 PMPCB AAR2 STOM ANO6 AKAP8L REEP6 COVID19-N protein host PPI from Krogan COVID19-N protein host PPI from Krogan CSNK2B LARP1 RPL36 RRP9 DDX21 UPF1 SNIP1 FAM98A PABPC4 RBM28 CSNK2A2 PABPC1 G3BP1 MOV10 G3BP2 COVID19-Nsp1 protein host PPI from Krogan COVID19-Nsp1 protein host PPI from Krogan PRIM2 PKP2 COLGALT1 POLA1 PRIM1 POLA2 COVID19-Nsp10 protein host PPI from Krogan COVID19-Nsp10 protein host PPI from Krogan AP2A2 ERGIC1 GRPEL1 AP2M1 GFER COVID19-Nsp12 protein host PPI from Krogan COVID19-Nsp12 protein host PPI from Krogan PPIL3 TCF12 ZC3H7A LARP4B BCKDK AKAP8 RIPK1 SLU7 PDZD11 TYSND1 PRRC2B UBAP2 UBAP2L MYCBP2 USP54 RBM41 CRTC3 ZNF318 SBNO1 PLEKHA5 COVID19-Nsp13 protein host PPI from Krogan COVID19-Nsp13 protein host PPI from Krogan CEP250 CEP112 CEP350 CEP43 GCC2 NIN CNTRL CDK5RAP2 NINL PRKACA TBK1 GCC1 TLE5 JAKMIP1 GOLGA3 CEP135 MIPOL1 HOOK1 CENPF GOLGA2 USP13 CIT TLE3 CEP68 FYCO1 GRIPAP1 RDX CLIP4 TLE1 HSBP1 PCNT PRKAR2B AKAP9 TBKBP1 PRKAR2A GORASP1 GOLGB1 PDE4DIP ERC1 C1ORF50 COVID19-Nsp14 protein host PPI from Krogan COVID19-Nsp14 protein host PPI from Krogan GLA IMPDH2 SIRT5 COVID19-Nsp15 protein host PPI from Krogan COVID19-Nsp15 protein host PPI from Krogan RNF41 NUTF2 ARF6 COVID19-Nsp2 protein host PPI from Krogan COVID19-Nsp2 protein host PPI from Krogan WASHC4 SLC27A2 GIGYF2 RAP1GDS1 EIF4E2 POR FKBP15 COVID19-Nsp4 protein host PPI from Krogan COVID19-Nsp4 protein host PPI from Krogan NUP210 TIMM10B IDE DNAJC11 TIMM9 TIMM29 TIMM10 ALG11 COVID19-Nsp5 protein host PPI from Krogan COVID19-Nsp5 protein host PPI from Krogan HDAC2 TRMT1 GPX1 COVID19-Nsp6 protein host PPI from Krogan COVID19-Nsp6 protein host PPI from Krogan ATP13A3 ATP6AP1 ATP5MG SIGMAR1 COVID19-Nsp7 protein host PPI from Krogan COVID19-Nsp7 protein host PPI from Krogan DCAKD RAB2A COMT LMAN2 MOGS RHOA RALA CYB5B TOR1AIP1 NDUFAF2 SCCPDH GNG5 ACSL3 RAB8A FAM162A RAB18 RAB14 AGPS SELENOS QSOX2 CYB5R3 MTARC1 RAB7A GNB1 HS2ST1 RAB1A PTGES2 NAT14 DNAJC19 RAB10 SCARB1 RAB5C COVID19-Nsp8 protein host PPI from Krogan COVID19-Nsp8 protein host PPI from Krogan SRP19 MPHOSPH10 ATE1 DDX10 HECTD1 EXOSC3 EXOSC8 NOL10 NGDN AATF MRPS2 SEPSECS SRP54 MRPS5 LARP7 MRPS27 MRPS25 NARS2 MEPCE SRP72 EXOSC2 EXOSC5 NSD2 CCDC86 COVID19-Nsp9 protein host PPI from Krogan COVID19-Nsp9 protein host PPI from Krogan EIF4H NUP54 NEK9 NUP62 MIB1 GTF2F2 FBLN5 NUP58 FBN1 NUP214 NUP88 FBN2 MAT2B ZNF503 DCAF7 SPART COVID19-Nsp10 protein host PPI from Krogan COVID19-Nsp10 protein host PPI from Krogan TIMM8B MAP7D1 PPT1 RBX1 ZYG11B CUL2 ELOB THTPA ELOC COVID19-Orf3a protein host PPI from Krogan COVID19-Orf3a protein host PPI from Krogan TRIM59 SUN2 HMOX1 ALG5 ARL6IP6 CLCC1 VPS39 VPS11 COVID19-Orf6 protein host PPI from Krogan COVID19-Orf6 protein host PPI from Krogan RAE1 NUP98 MTCH1 COVID19-Orf7a protein host PPI from Krogan COVID19-Orf7a protein host PPI from Krogan MDN1 HEATR3 COVID19-Orf8 protein host PPI from Krogan COVID19-Orf8 protein host PPI from Krogan FOXRED2 ADAMTS1 EMC1 CHPF2 OS9 GDF15 FKBP10 COL6A1 ERLEC1 ERO1B HYOU1 LOX CISD3 CHPF FKBP7 SMOC1 ITGB1 TOR1A NPC2 PUSL1 PVR PLEKHF2 FBXL12 ADAM9 TM2D3 NPTX1 UGGT2 NGLY1 POFUT1 DNMT1 INHBE ERP44 PLOD2 POGLUT2 SDF2 MFGE8 PLD3 PCSK6 PLAT EDEM3 POGLUT3 SIL1 IL17RA GGH STC2 HS6ST2 NEU1 COVID19-Orf9b protein host PPI from Krogan COVID19-Orf9b protein host PPI from Krogan DCTPP1 PTBP2 CSDE1 SLC9A3R1 MARK3 MARK1 MARK2 CHMP2A DPH5 TOMM70 BAG5 COVID19-Orf9c protein host PPI from Krogan COVID19-Orf9c protein host PPI from Krogan NDFIP2 F2RL1 ERMP1 PIGS ABCC1 GHITM SCAP DPY19L1 ACAD9 TMEM97 RETREG3 ECSIT GPAA1 FAR2 PIGO BCS1L TAPT1 TMEM39B NDUFB9 ALG8 NLRX1 WFS1 UBXN8 TMED5 NDUFAF1 SLC30A6 COVID19-Spike protein host PPI from Krogan COVID19-Spike protein host PPI from Krogan GOLGA7 ZDHHC5 COVID19-All 332 protein host PPI from Krogan COVID19-All 332 protein host PPI from Krogan NDFIP2 NUP210 GLA SRP19 F2RL1 EIF4H FOXRED2 TIMM10B DCTPP1 ADAMTS1 PPIL3 DCAKD CSNK2B EMC1 CEP250 CHPF2 AP2A2 RTN4 IMPDH2 TIMM8B TARS2 CEP112 TBCA CEP350 ERMP1 MPHOSPH10 RAB2A HDAC2 FAM8A1 CEP43 ATE1 ATP13A3 OS9 GCC2 NIN GDF15 PSMD8 PIGS CNTRL FKBP10 IDE CDK5RAP2 NINL COL6A1 ERLEC1 ERO1B ATP6AP1 TRMT1 HYOU1 TCF12 ABCC1 DDX10 ZC3H7A HECTD1 MDN1 TRIM59 PRIM2 LARP1 GHITM LOX ERGIC1 CISD3 CHPF COMT SUN2 SLC25A21 ETFA RPL36 DNAJC11 WASHC4 PTBP2 NUP54 FKBP7 PRKACA NEK9 SMOC1 ATP5MG CSDE1 SLC27A2 EXOSC3 MAP7D1 ITGB1 PKP2 LMAN2 MOGS LARP4B BCKDK SLC9A3R1 AKAP8 EXOSC8 SCAP TUBGCP2 TBK1 TOR1A NUP62 ACADM RRP9 GCC1 DDX21 SAAL1 NPC2 TLE5 ATP6V1A MIB1 RHOA UPF1 RIPK1 NOL10 DPY19L1 TUBGCP3 HEATR3 SLU7 JAKMIP1 GOLGA7 PDZD11 PUSL1 ACAD9 GOLGA3 PPT1 TIMM9 RALA NGDN CEP135 CYB5B YIF1A TYSND1 AP3B1 AATF TOR1AIP1 TMEM97 RETREG3 COLGALT1 CWC27 RBX1 PVR NDUFAF2 ZC3H18 SCCPDH SLC30A9 PLEKHF2 MIPOL1 GTF2F2 PRRC2B HOOK1 FBLN5 FBXL12 ECSIT MRPS2 ADAM9 GNG5 TM2D3 STOML2 CENPF ACSL3 SEPSECS GRPEL1 GPAA1 SRP54 SIGMAR1 FAR2 RNF41 GOLGA2 UBAP2 USP13 AP2M1 NUP58 NPTX1 MRPS5 COQ8B CIT TIMM29 TLE3 PIGO PITRM1 LARP7 ZYG11B RAB8A MRPS27 FAM162A POLA1 HMOX1 CEP68 UGGT2 GPX1 BRD2 ALG5 FYCO1 RAB18 FASTKD5 SNIP1 RAB14 BCS1L BZW2 TAPT1 AGPS TMEM39B NGLY1 GIGYF2 POFUT1 PMPCA GGCX DNMT1 RAP1GDS1 GRIPAP1 SELENOS INHBE EIF4E2 FAM98A RDX PABPC4 MARK3 ERP44 QSOX2 ATP1B1 CUL2 PLOD2 ARL6IP6 ZDHHC5 NUTF2 RBM28 POGLUT2 SDF2 CLIP4 MRPS25 AASS TLE1 CSNK2A2 UBAP2L NARS2 CYB5R3 PRIM1 MFGE8 MTARC1 FBN1 REEP5 NDUFB9 MYCBP2 CLCC1 SIRT5 POR SLC30A7 PLD3 ALG8 MEPCE SRP72 NUP214 INTS4 NLRX1 RAB7A USP54 RBM41 HSBP1 PABPC1 PCNT FKBP15 PCSK6 RAE1 PLAT PMPCB POLA2 MARK1 TIMM10 WFS1 NUP88 FBN2 PRKAR2B BRD4 ELOB GNB1 G3BP1 AAR2 CRTC3 AKAP9 VPS39 MOV10 EXOSC2 EXOSC5 NUP98 VPS11 ZNF318 SBNO1 ALG11 STOM MAT2B EDEM3 POGLUT3 NSD2 HS2ST1 SIL1 TBKBP1 MTCH1 PRKAR2A UBXN8 TMED5 IL17RA MARK2 CCDC86 ANO6 GORASP1 AKAP8L ARF6 RAB1A NDUFAF1 ZNF503 PTGES2 DCAF7 GOLGB1 NAT14 THTPA ELOC DNAJC19 RAB10 SCARB1 CHMP2A SLC44A2 SLC30A6 REEP6 DPH5 GGH TOMM70 GFER STC2 BAG5 SPART HS6ST2 G3BP2 RAB5C PDE4DIP NEU1 PLEKHA5 ERC1 C1ORF50 ACE2 Co-expressed genes from ARCHS4 ACE2 is the likely the receptor for COVID-19 enabling its entry into cells BTNL6 MOGAT2 CYP4F14 TM4SF20 LCT CYP3A13 ERICH4 CYP2C65 EPS8L3 NAALADL1 SIS CYP2C66 CLEC2E 9130409J20RIK TM6SF2 ANPEP SLC2A7 MALL IGSF23 IFI27L2B SLC7A15 ADH6A 2010003K11RIK CDH17 ENPP3 HNF4G ALPI RBP2 SLC26A6 MYO1A MALRD1 SLC13A2 SECTM1B MS4A18 MYO15B SLC5A4A SMIM24 NPC1L1 VIL1 BTNL1 MTTP MYRFL 2010106E10RIK BTNL5-PS ISX ACSL5 REG3A FABP2 SLC5A1 SLC6A19 THEMIS3 CDHR5 GIMD1 ADA MEP1B CLEC2H CES2E CLCA4A CLDN15 SLC28A1 SLC15A1 ENPEP SLC7A9 CLRN3 CLCA4B PLS1 BAIAP2L2 DNASE1 SULT1B1 AOC1 SLC27A4 APOA4 ENPP7 MYO7B ANXA13 ST3GAL4 ACE BTNL2 TREH TM4SF5 CHP2 PTPRH IL22RA1 USH1C GLOD5 GM8909 TRIM31 H2-T3 CCL25 KRT20 SLC5A12 BTNL4 GUCY2C ASAH2 HKDC1 MS4A10 ARL14 BTNL7-PS CDHR2 TMEM236 ACE2 top 50 Geneshot AutoRIF Genes co-published with ACE2 based on AutoRIF SYVN1 SLC6A18 SOX14 CYP11B2 NOX4 CMA1 APLNR ANPEP TMPRSS2 RPL12 SLC6A20 SCAP MME ACE2 SWI5 CRYGA RNPEP CPA2 ATP6AP2 AGTR2 IGSF3 SLC6A19 LAP3 COL4A3 ZNF274 CLCN6 EHBP1 ENPEP CALM3 MID2 CTSD ADAM17 TMPRSS11A ACE NR3C2 AGT AGTR1 UTS2 MAS1 ITM2A CRYGB CLEC4M AGTRAP TGFB1 NUP85 MOB2 RNLS THOP1 REN LNPEP ACE2 top 200 Geneshot AutoRIF ARCHS4 predictions Genes co-published with ACE2 based on AutoRIF and then enriched for genes that co-expressed with these genes MAOA ANO9 SLC36A1 GNA11 MOGAT2 TMEM82 GAK TM4SF20 SLC10A2 MISP FAM3B ERICH4 CES2 NBL1 SEC16B EPS8L3 NAALADL1 NR1I2 FCGRT MAPK3 SLC13A1 CPO DPP4 CAPN5 CUBN CYP4F12 GLYCTK PBLD TM6SF2 SLC17A4 TMEM37 MVP ANPEP CYP3A4 CTDSP1 PRAP1 ADAMDEC1 MALL VDR FBXW5 BTNL3 DEFA5 SI TMIGD1 DGAT1 C1ORF115 AADAC SLC1A1 CDH17 HNF4G PCK2 CREB3L3 OTC GUCA2A CEACAM20 UGT2A3 RBP2 NR1H4 MYO1A MALRD1 SLC13A2 DPEP1 ESRRA ZZEF1 MYO1D HSD11B2 SLC7A7 ACE2 PPP1R14D TRIM15 MYO15B CYP2J2 VIL1 CYP4F2 GPT MTTP SEPP1 TMBIM1 GBA3 PFKL FABP1 SLC22A18 PDZD3 PRR15L GUCA2B ENTPD8 XPNPEP2 ISX KHK ACSL5 TUBAL3 CDX2 REG3A FABP2 SLC5A1 SDCBP2 SLC6A19 TPRN CRYL1 ST14 VILL ZBTB7B KCNQ1 CDHR5 VIPR1 GPA33 GGT1 SLC46A3 MEP1B LRRC66 LRRC19 FAM109A NLRP6 SLC9A3 CDX1 AMN TMEM54 CLDN15 SLC28A1 SLC15A1 ENPEP HNF4A SLC7A9 ACAA1 BTNL8 TCN2 NAGS PLCB3 CLRN3 PLS1 BAIAP2L2 HEPH DEFA6 KIAA2013 MTMR11 PHGR1 APOA4 DMBT1 REG4 NUCB1 CYP2C18 FABP6 TST ACE GIPC2 TREH ACADVL TMEM176A CHP2 ABCG2 TSPAN8 MGAT4B CNDP2 PTPRH RETSAT EPS8L2 SLC5A9 ACY1 CLCA1 USH1C MUC3A TDP2 LGALS4 PCK1 MUC17 MGAM PEPD DHRS11 ADGRG7 UNC5CL MEP1A PLB1 HHLA2 ITLN2 SLC23A1 KCNJ13 SULT1A2 ALDOB CCL25 KRT20 SLC5A12 AKR7A3 C17ORF78 TTC38 EPHX2 AGPAT2 GUCY2C FLJ22763 C11ORF86 FBP1 ACADS TKFC MUC13 REEP6 FCGBP ENTPD5 CDHR2 UGT2B17 TMEM253 SLC39A5 ACE2 top 200 Geneshot AutoRIF Enrichr co-occurrence predictions Genes co-published with ACE2 based on AutoRIF and then enriched for genes that co-occur in Enrichr submissions with these genes ZP4 SLC25A31 TEKT3 OR6B3 RGS21 FGF6 GCGR RHPN2P1 GPR151 TGM6 SNARC5 PRAC2 ERICH4 SPATA31E1 PRSS42 TMEM202 OR7A17 SPAM1 OR1L3 OR6A2 SYNGR4 SLC5A2 PRSS55 SLC13A1 GDF2 TMEM247 UTS2R GIF GHRH OR8D2 RNF133 TRBV102 WFIKKN1 OR2W1 TGM4 UGT1A7 H1FOO OR1G1 OR1I1 TRIM42 FGF23 ZNF252PAS1 PDHA2 TAAR1 SAXO1 SNARA8 TMEM239 SLC4A9 TAAR8 SPATA21 ACTRT2 PRSS58 OR1A1 CRYGD PTCRA FTH1P18 TINAG ALPI PRSS37 SSX7 UROC1 TEX35 OR1Q1 OR4X2 OR10A4 SPACA3 CRX AGRP ANKS4B TBC1D3P5 SMIM2IT1 UBE2DNL GABRA6 HMGB4 OR1F2P TBC1D29 SLC16A8 SLC25A41 RTP2 SLC22A9 GALR2 SNARA13 OR13J1 WFDC10A OPN1LW OR1N2 TP53AIP1 TAS2R40 PGLYRP4 OR3A2 CRYBB2 OR1L4 SULT1C3 UNC93A SLC30A2 GUCA2B SNARI SSX5 F13B ADGRD2 REG3A TERB1 OR3A3 OR2J3 OR6Y1 ZP2 SLFNL1 OR1F1 TAS1R2 PGC TBX10 A4GNT RPS2P52 TAAR9 AMELY HIGD1AP11 ODF4 PSG6 FAM71C TRIM64 CRYGC OR13C4 HOXD12 TAAR2 TEX11 AQP2 AKAP4 FAM170A OR10G3 FAM71B OR10H2 TPD52L3 CRYAA SLC7A9 FAM71E2 GPR20 TREML3P OR1C1 PDZD9 TMEM61 OR1A2 TMC2 TEX13B RSPH6A SPATA19 ACTRT1 TRIM40 TSPYL6 REG1B TMEM270 GPR142 OR10A6 TEX36 CRYGN PDILT ETDB PRSS50 TREH TEX28 OR5AK2 TEX47 ANKRD66 GALR3 GRK7 FAM215A FBXW12 OR6C3 PTGER1 AQP12A TMCO2 TEX12 POM121L4P SMCO2 CRYBB3 CRYBA2 PTH ZNF575 HOXBAS4 CRYGB OR10H1 PGLYRP3 FAM221B TAS2R38 PICSAR AFM TTTY22 PRSS47 OR1N1 WFDC6 TAS2R39 SEMG2 OR1S2 ODF1 SEPT12 SPEM1 UMOD OR51B6 OR8J1 WFDC5 PPY2P SARS top 50 Geneshot AutoRIF Genes co-published with the terms SARS based on AutoRIF TRIM55 ENDOU SARS2 DPP4 FKBP1A EIF3F FGL2 ANPEP TMPRSS2 CTSL GHITM YWHAQ IRF3 TOM1L2 HIST1H1C TBK1 COPB1 CXCL10 ACE2 IFITM3 IL17RD PLA2G2D IFITM1 RASA3 FCER2 FURIN SARS VIT COPB2 SIX3 GNGT2 TMPRSS11A STAT1 TRAF3 IFITM2 CLEC4G DEDD WARS2 RARS CLEC4M PPIG ISG15 PPIH RPH3A FKBP1B PPIA LRRC2 PLP2 EDEM1 MX1 TMPRSS2 top 50 Geneshot AutoRIF Genes co-published with the term TMPRSS2 based on AutoRIF NKX3-1 AMACR CANT1 RSRC2 SH3BGR FAM71D SEC14L1 TMPRSS2 PTEN SPOP SPINK1 TMPRSS3 SLC45A3 SHQ1 RNF24 TMEM65 CACNA1D MAST4 TMPRSS4 ANXA3 KLK3 NDRG1 TMPRSS5 ETV1 ETV4 TDRD1 PMEPA1 HOOK3 ERG RYBP CRISP3 TMPRSS7 NCKAP5 TMPRSS11D ST6GALNAC1 NT5C FOXA1 ELK4 HSPBAP1 SLC16A6 PES1 ETV5 KLK2 FAM72B UAP1 TMPRSS13 PIGU CHD1 TOP2B UMODL1 SARS 133 Literature-Associated Genes from Geneshot GeneRIF SARS (severe acute respiratory syndrome) is caused by coronavirus, and the term SARS is a component of the name of COVID-19 (SARS-CoV-2) as well as referring to earlier historical SARS-CoV viruses. TICAM2 GOT1 UBB CASP6 IL2 CD209 IFNAR1 PPBP IL1B BCL2L1 EEF1A1 IL6 MAPK3 RB1 SFTPD CD14 DPP4 IFNA1 FGL2 POU5F1 CCL2 CCL5 CD34 EGR1 TMPRSS2 CTSL IL17A NUDT2 VCP MAP1LC3A NMI TNF KPNB1 IRF3 CXCL5 KPNA2 DDX5 DDX58 EIF2S1 TSPO VHL TBK1 RCHY1 IL1A HLA-DQA2 MPP5 CXCL10 CCND3 ACE2 IFITM3 TLR4 CXCL16 EZR PLA2G2D GPT AHSG ATF6 IFITM1 PF4 ZCRB1 DDX1 FCER2 ANXA2 HLA-B THPO SARS RUNX1 HSPB1 KLF6 IFNG F5 CLTRN SMAD3 IL12B CTNNB1 IFNL3 NFKB1 HMOX1 IL4 MAPK14 HOXA9 SERPINE1 PHB2 OAS1 PKLR CFP FCGR2A PTX3 HLA-DRB1 PSMC6 TP53 HLA-C ADAM17 RELA ACE STAT1 TRIM25 HLA-A CANX TMPRSS11D CLEC4G EIF2AK2 IL12RB1 TMEM173 WARS2 F2 C11ORF74 APOBEC3G PHB NOS3 MASP2 CLEC4M PI4KB CXCL2 IFNB1 NPIPB3 ISG15 EGFR BDKRB1 UBE2I MBL2 ICAM3 SPI1 PPIA CXCL9 CASP3 CSF2 IL10 STAT6 MX1 MYD88 MAPK1 ESM1 ACE2 Pathway from BioCarta 2013 ACE2 is the likely point of entry for COVID-19. This list of from a BioCarta pathway from 2013. CMA1 COL4A6 COL4A5 ACE2 AGTR2 COL4A1 COL4A3 COL4A2 COL4A4 AGT AGTR1 REN ACE2 PPI from the NCBI Gene database ACE2 is the receptor for COVID-19 HRAS ACE2 DLEU2 CALM1 AGT ISYNA1 AAMP CAT NTS GHRL SARS coronavirus protease from BioPlanet 2019 SARS coronavirus protease pathway genes from BioPlanet ANPEP CKM GPT NCL MAPK14 FBL EIF4E SARS coronavirus endoRNAse (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus endoRNAse (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB RB1 RBL1 UBC RBL2 ISG15 SARS coronavirus protein E (gene: E) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus protein E (gene: E) from Virus-Host PPI P-HIPSTer STMN4 RAD23B STAT3 EP300 HSPA4 ESR1 BAG3 CTNNB1 STAT1 VARS BRD4 SRC APP CDK2 GRB2 SARS coronavirus hypothetical protein sars7a from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus hypothetical protein sars7a from Virus-Host PPI P-HIPSTer KIR3DS1 VCAM1 STAT3 UBD YWHAQ PFAS LILRB2 UBC YWHAZ DAAM1 YWHAG ARRB2 EZR YWHAB ARHGEF4 YWHAE BAG3 PSMD4 FN1 FASLG STAT1 VARS PDE4D FMNL1 SRPK2 B2M SFN WASF1 BRCA1 ARHGEF11 ITGA4 CD8A YWHAH SRC DIAPH1 LILRB1 EVL GRB2 SARS coronavirus hypothetical protein sars9b from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus hypothetical protein sars9b from Virus-Host PPI P-HIPSTer SUMO2 SQSTM1 YWHAQ UBC YWHAZ YWHAG YWHAB ARHGEF4 YWHAE ATM TARS B2M SFN NPM1 YWHAH SRC GRB2 SARS coronavirus excised_polyprotein 1..4369 (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus excised_polyprotein 1..4369 (gene: orf1ab) from Virus-Host PPI P-HIPSTer MYH9 UBB SPTB PTPN14 JAK1 UBQLN3 SUMO1 UBL5 UIMC1 RPS27A PIK3R2 UHRF1 BIRC3 KIR3DS1 RB1 RBL1 RAD23B HSP90AB1 UBE2D2 SUMO3 PRKCZ HSPA5 ZFAND4 XPO6 VCAM1 STAT3 FRMD7 APC SUMO2 GMIP SQSTM1 UBD SPTAN1 YWHAQ PFAS EPB41L2 PTPN3 BCAR1 SNX1 UBXN6 PTPN21 CAPN2 PPP2R1A UBXN2A UBC YWHAZ RPL13 ASAP2 MACF1 UBE2D3 RBL2 EPB41 TMUB1 UBE2K UBQLN4 BAIAP2L1 EPB41L1 YWHAG EP300 RNF2 ARRB2 EZR TPM4 FAF1 UBL4B DDI2 YWHAB UBXN1 ABL1 TPM3 ARHGEF4 PKM NBR1 HSPA4 ATXN3 YWHAE ELAVL1 LYN ING5 CUL1 GABARAPL2 NF2 GRIN1 EPS15 NEDD9 BRAF DYNC1H1 IQUB UBA1 UBE2D1 ASPSCR1 ANKUB1 ESR1 FRMPD4 JAK2 SNX31 BAG3 SPTA1 XIAP WRN HSP90AA1 ABI1 TUBA1A CTNNB1 ANXA11 NCK1 UBTD1 USP2 FRMD6 RBCK1 UHRF2 H3F3A NFATC2IP CALM1 SPTBN5 FRMPD3 UBA52 PSMD4 UBQLN1 DDI1 ATM ING4 SPTBN2 BIRC2 FN1 RAD23A HIST1H4A UBQLNL SF3A1 TARS CRK EPB41L5 STAT1 UBTD2 VARS SAP18 HGS B2M SFN SDE2 ERBB2 BRCA1 EPB41L3 BAG6 USP11 TMUB2 USP48 TRIM28 FAU HERPUD1 FYN PABPC1 ITGA4 OASL NPLOC4 RCC1 NEDD8 FRMD1 PXN MSN SMARCA4 FRMD4B USP21 TLN2 ING3 SHARPIN PLS3 USP15 CD8A YWHAH FERMT3 ISG15 SRC EGFR HSPA8 HERPUD2 FRMD3 MAP3K1 APP LILRB1 FERMT2 CSNK2A1 NUB1 PTPN4 UBFD1 UBQLN2 USP7 FRMD8 PLEC FRMD8P1 PTK2 RCOR1 SPTBN1 GRB2 SARS coronavirus 2-O-ribose methyltransferase (2-o-MT) (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus 2-O-ribose methyltransferase (2-o-MT) (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB RB1 RBL1 PFAS UBC RBL2 ELAVL1 STAT1 BRCA1 ISG15 GRB2 SARS coronavirus leader protein (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus leader protein (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB STAT3 YWHAQ UBC YWHAZ YWHAG YWHAB ABL1 ARHGEF4 YWHAE LYN NCK1 CRK STAT1 SFN FYN YWHAH ISG15 SRC GRB2 SARS coronavirus formerly known as growth-factor-like protein (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus formerly known as growth-factor-like protein (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB STAT3 YWHAQ UBC YWHAZ YWHAG YWHAB ARHGEF4 YWHAE STAT1 VARS SFN YWHAH ISG15 SRC APP GRB2 SARS coronavirus nsp7-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus nsp7-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB SPTB RAD23B HSPA5 YWHAQ UBC YWHAZ BAIAP2L1 YWHAG EP300 EZR YWHAB YWHAE ING5 ESR1 BAG3 CTNNB1 CALM1 HBQ1 HBD FN1 STAT1 VARS B2M SFN BRCA1 PXN MSN YWHAH ISG15 HSPA8 APP HBM KALRN SPTBN1 HBG1 SARS coronavirus nsp9-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus nsp9-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB HSPA5 STAT3 UBC ARHGEF4 BAG3 ATM STAT1 CD8A ISG15 SRC APP GRB2 SARS coronavirus nucleocapsid protein (gene: N) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus nucleocapsid protein (gene: N) from Virus-Host PPI P-HIPSTer STAT3 YWHAQ TRIB3 YWHAZ YWHAG EP300 YWHAB YWHAE TUBA8 TUBB4B ESR1 TUBA1A TUBA3C CTNNB1 TUBA1C ATM FN1 TUBA4A STAT1 B2M SFN BRCA1 NPM1 YWHAH SRC GSK3B CSNK2A1 CDK2 GRB2 SARS coronavirus nsp3-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus nsp3-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer MYH9 UBB PTPN14 JAK1 UBQLN3 SUMO1 UBL5 UIMC1 RPS27A UHRF1 RB1 RBL1 RAD23B SUMO3 PRKCZ ZFAND4 STAT3 FRMD7 SUMO2 SQSTM1 UBD VCP YWHAQ UBXN6 PTPN21 UBC YWHAZ RBL2 EPB41 TMUB1 UBQLN4 EPB41L1 YWHAG RNF2 EZR FAF1 UBL4B DDI2 YWHAB UBXN1 ARHGEF4 NBR1 ATXN3 YWHAE GABARAPL2 NF2 EPS15 BRAF IQUB ASPSCR1 ANKUB1 ESR1 FRMPD4 JAK2 SNX31 BAG3 UBTD1 FRMD6 RBCK1 UHRF2 NFATC2IP FRMPD3 UBA52 PSMD4 UBQLN1 DDI1 ATM FN1 RAD23A UBQLNL SF3A1 TARS EPB41L5 STAT1 UBTD2 VARS SAP18 HGS SFN SDE2 BRCA1 EPB41L3 BAG6 USP11 TMUB2 USP48 FAU HERPUD1 ITGA4 OASL NPLOC4 NEDD8 FRMD1 MSN FRMD4B TLN2 SHARPIN USP15 CD8A YWHAH FERMT3 ISG15 SRC HERPUD2 FRMD3 MAP3K1 EPB41L4A APP LILRB1 FERMT2 NUB1 PTPN4 UBFD1 UBQLN2 FRMD8 PAICS PTK2 GRB2 SARS coronavirus nsp8-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus nsp8-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB RAD23B STAT3 SPTAN1 BCAR1 STX3 CAPN2 UBC RPL13 MACF1 BAIAP2L1 EP300 ARRB2 EZR TPM4 TPM3 NBR1 HSPA4 ELAVL1 CUL1 NEDD9 DYNC1H1 BAG3 SPTA1 ABI1 TUBA1A CTNNB1 H3F3A SPTBN5 ATM FN1 HIST1H4A STAT1 ERBB2 BRCA1 CHRNB1 MSN SMARCA4 ISG15 SRC APP PLEC RCOR1 SPTBN1 GRB2 SARS coronavirus RNA-dependent RNA polymerase (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus RNA-dependent RNA polymerase (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB TRIB3 UBC YWHAZ YWHAG YWHAB ISG15 CDK2 GRB2 SARS coronavirus E2 glycoprotein precursor (gene: S) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus E2 glycoprotein precursor (gene: S) from Virus-Host PPI P-HIPSTer CD79B HAPLN2 IGSF8 KIR3DS1 VCAM1 STAT3 YWHAQ PDCD1 NPTN TRGV3 CD200R1L PFAS THY1 ICOS LILRB2 YWHAZ VPREB3 LSAMP SIRPD ACE2 YWHAG EP300 CTLA4 EZR YWHAB MIPEP ARHGEF4 SCN2B YWHAE ELAVL1 IGSF3 SIGLEC15 ESR1 BAG3 GPA33 CD200R1 HSP90AA1 SIRPA MPZL1 TTN TREM2 FLT1 MPZL3 PSMD4 ATM FN1 VSTM4 TARS ACE STAT1 B2M SFN BRCA1 CD7 MSN CD8B SIRPB2 CD8A YWHAH CD4 SRC VSIG4 APP VSTM2B CD244 LILRB1 Q6P2N6 NCAN SCN3B IGSF9 GRB2 MXRA8 SARS coronavirus nsp4-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus nsp4-pp1a/pp1ab (gene: orf1ab) from Virus-Host PPI P-HIPSTer UBB STAT3 YWHAQ UBC YWHAZ YWHAG EP300 YWHAB YWHAE STAT1 SFN BRCA1 YWHAH ISG15 SRC GRB2 SARS coronavirus P2 envelope protein from Virus-Host PPI P-HIPSTer 2020 SARS coronavirus P2 envelope protein from Virus-Host PPI P-HIPSTer STMN4 RAD23B STAT3 EP300 HSPA4 ESR1 BAG3 CTNNB1 STAT1 VARS BRD4 SRC APP CDK2 GRB2 COVID-19 patients BALF up Transcriptome sequencing data of the RNAs isolated from the bronchoalveolar lavage fluid (BALF) specimens of COVID-19 patients. NKX3-1 RPS27A TIMM8B EEF1A1 BIRC3 CCL2 EGR1 TMPRSS2 PTEN RPL12 SLC27A2 HIST1H1C MYO1D BAIAP2L1 IFITM3 CYP2J2 TMPRSS4 IFITM1 MIPOL1 HOOK1 IQUB H3F3A CRISP3 GNGT2 TSPAN8 TMPRSS11D ST6GALNAC1 ANKRD66 UTS2 CXCL2 EGFR MUC13 SPTBN1 PLEKHA5 ERC1 ARHGEF12 CNTD1 MPP7 RPS20 SNTN MYO10 RASEF AC018628.1 BPIFB1 RPL37A UCA1 SLITRK6 NBEA RPL24P4 RPS26 CEACAM6 ENKUR CYP2F1 PCLO PAICSP1 GAREM1 AC111149.2 DANCR RPS16 RPL15P3 RPS3AP6 SH3D19 PCP4L1 TPRG1 SERPINB11 PARVA TMC5 RPL21 SPRR3 CERKL RPL35A MECOM KRT5 TFF3 MT2A CP MUC21 RPL22P1 MT-ND3 VEPH1 HIST1H2BH TMEM71 CXCL1 SDC1 AC066616.2 ZNF253 HIST1H4B CXCL6 CLCA4 KRT18 CDK2AP1 TSHZ2 OSBPL6 SLC22A23 LINC01133 SLC16A9 MCF2L ITGA2 ARFGEF3 TGFB2 PPP1R14C AK4 FAM114A1 NT5DC2 AC104126.1 LMNTD1 AOPEP AC034236.1 STOX1 EEF1A1P6 ENAH TNFSF10 SRGAP1 RPL3P4 PERP RPS13P2 KRT7 PIGR RPL9 SPATA5 FAM229B RPLP2 NEBL POU5F2 C20ORF85 DDAH1 FBXL13 LMO3 FTLP3 AUTS2 AC024293.1 ZNF532 HIST1H2AL KCTD1 RPL18AP3 UQCR10 CCDC30 FRK ASS1 BEND7 CFTR TSGA10 TENT5C AC005912.1 ENTPD3 DNALI1 OLFML2B CCDC74A ATP12A MTATP6P1 MSMB AC092645.2 CEBPD NINJ1 AP001324.1 RARB MYO1B KLF5 TRPS1 RGS2 IL5RA AC026403.1 RPS12 RPL10AP6 INSYN2B FP671120.7 RNASE7 TM4SF1 IFI27 AC090498.1 ARL3 PART1 SLC15A2 SIX1 AQP4-AS1 RBPMS A2ML1 KRT4 REPS2 AC079793.1 HS3ST1 RAB40B BMPR1B LSM12 RPS11 RPL14P1 ERBB3 KRT17 HES1 TTC9 CCDC7 RPL14 SERPINB3 DUSP16 RN7SL1 FTH1P8 CGNL1 MTCO3P12 EXT1 ZEB2 SLC40A1 HIST1H2BC EEF1A1P5 SOX2-OT MCTP2 RPL27 CCL3L1 ADCY2 AL162377.1 DPRXP4 TTC39A FAM216B C1ORF21 FGF14 ECM1 FGFR2 STK33 RPL7P9 GULP1 FYB1 IL33 RPL37P2 MT-ND1 ZC3H12D MAL THRB ALMS1 AC099336.2 HTN1 MT-RNR1 AC138393.1 AC069549.2 PARD6B LRRC18 MXRA7 MT-ND5 NT5E CCDC84 IGSF6 SLC4A4 HLF RPL41 CEP170P1 RPS15A AQP5 NR4A2 MTRNR2L8 GASK1B HIST1H4I RPS24 STARD13-AS GCNT3 RAI14 UPK1B TPT1 FBXO36 OMG MUC15 SCGB3A1 SYTL2 YAP1 SH3BGRL2 RPL12P4 FAM117B MT-CO1 METTL23 MT-ND6 ZNF204P RPL6 ZFP1 SH3RF1 RPL37 AL450998.1 S100P COBL GPX2 DUOX2 FTH1P7 AL357093.2 FMO3 TSPAN6 PPIL6 FDCSP DEPTOR PATJ HIST1H2AG SERPINB5 HOPX MT1E KLK11 COBLL1 CNTN5 NEK10 RTEL1P1 KIF21A NFAT5 C9ORF116 METTL7B RPS8 CXCL17 ZNF91 AC011933.2 LINC00342 SOX21-AS1 LZTS3 S100A14 RAB25 NME5 APLF RPS3AP26 LRIG3 ELF3 CRYM PKP4 FOPNL TRIM52-AS1 PTPN13 TEAD1 GATAD2B RALGPS2 LURAP1L RPL38 PPL LINC01315 MAP3K19 H3F3AP4 LMO7 MYRIP HTN3 C6ORF132 SMPDL3A PBX1 TOX3 AL035661.1 AL133243.4 HIST1H1E FOXP2 NFIB NDUFB2 SNORD17 RNF152 HIST2H2AC ZNF564 RPL7AP6 MYO5B CNN3 RHOBTB3 SPAG16 CA8 OSMR USF3 RPS3A KIAA1217 PNRC1 COLCA1 PAX9 CCNO PEAK1 FREM2 RASSF6 TNS4 HUNK CFH MTRNR2L12 PAWR NCKAP1 TRIM2 AC116533.1 MZT2A TMEM232 CD180 AC009951.4 SOX2 RICTOR PITX1 CCDC80 SPINT1-AS1 SCEL GALNT3 RN7SL3 MARCKS MTRNR2L1 HEY1 C3ORF67 FAM83B DSG2 PLCE1 WFDC2 KIAA1324 ITGA10 RPL21P16 SERPINB2 WDFY3-AS2 TP63 ADH1C MT-TP MT-RNR2 QSER1 FNIP2 KLHDC9 SHISA6 GALNT5 RPL7P1 HSPB8 ZNF460 AC013264.1 TCP11L2 C1ORF116 FTH1P20 RPL13P12 PRKAA2 PLCB4 NPM1P27 AL033523.1 SHOC1 H19 STEAP4 RPL30 AC105052.5 SPRR1A APOBEC3A HIST2H2AB HIST1H2BK SNORA79B CYP2B7P SMIM31 AL590867.2 BCAS1 SPRR2D AC073861.1 SNORA73B PALM2-AKAP2 ZNF827 MT-ND2 SLC25A4 ADH7 EVA1C RPL23 MT-ND4L RPL13A C12ORF75 RN7SL5P RPL21P28 PTGFR CEP295NL EPCAM CDC14B FAM214A MT-CO3 COX6A1 RPL24 RPS7P1 MTCO2P11 LINC00632 MAP6 RPS25 RPS15AP1 C4ORF19 ZEB1 TET2 SCIN ADGRL2 USP51 SLC2A1 FAM204BP FZD6 DLGAP1-AS1 RPSA GADD45A LINC00630 RPL39P3 SLC16A7 MTCO2P12 CYBRD1 TSTD1 SATB1 CKS2 KRT19 ANKRD36C RND3 FNBP1L SYTL5 SLX4IP RPS15 HIST1H2BD ANKRD33B PRDM1 WDR38 WDR63 AC122718.1 ZNF750 PTN C9ORF24 KRT15 RPL41P1 PRSS16 STATH KLHL6-AS1 MUC16 AC016739.1 OTUD7B SEMA3A AL033519.3 SETBP1 RPS2P46 AC012066.2 CRCT1 POF1B HIST1H4H UTRN HIST1H2AC EFHD1 ADAM28 INPP4B MALAT1 DYNLRB2 CLCA2 TRIM29 SLPI MTCO1P12 RGL1 FMN1 ZNF507 RPL39 ATOX1 MAPK10 NDRG2 BDP1 SSBP2 RPS13 AC006141.1 ZNF850 MTND5P32 MAPK6P3 TJP1 FAM183A TFF1 MTND1P23 SPINK5 MORN5 BEND5 TMPRSS11B FOXQ1 CD300E SAMD12 EXPH5 TRIM7 ADGRG1 MT-CYB SGPP2 LINC01765 PRSS23 GPRC5A HTRA1 AL139100.1 SIX4 CEACAM5 MT-ATP6 ACOT13 S100A2 RPS18 SORBS2 EYA1 AC114760.2 ACTR3C LINC01881 CCL8 RIMS1 ESRP1 MBNL2 TACSTD2 GSTA1 BBOF1 COX7C ZNF467 ZNF33B KIAA1671 RPL19 RPL6P27 C2ORF73 ISG20 ABLIM1 EYA4 KIAA1143 PSCA LINC02541 PIP PTPRZ1 PLA2G7 AGAP1 LCN2 MT-ND4 TMPRSS11E HIST1H1D CRNN AGR2 ANK3 KRT8 RPS27AP16 TACC2 ABCA1 RPS29 PLEKHG1 EHF TMIGD3 GCNT4 RPL7A DCDC1 CFAP53 MEIS1 CEP170 CHST9 AC012066.1 KCNQ1OT1 TPST1 TPD52 MYO5C AIF1 IGLC2 SNHG16 DDX10P1 AC004765.1 MAP7 RPL13AP5 CCL4L2 COPS9 FMO2 WDR78 STARD10 TEX26 MT-CO2 GRAMD2B NFIA FTH1P10 ZC3HAV1L RPL31 RPSAP58 RPLP1 EMP2 RPL13AP25 AC007996.1 ZBTB20 SRGAP3-AS2 RPL11 RPS23P8 RPS14 DHRS9 ZNF462 SLC25A23 AKAP14 ARID5B TC2N HESX1 SYBU CHCHD10 RPL26P19 APTR RPS7 AADAT CCND1 RPL7 TMEM246 PLEKHS1 NEDD4L TTC22 RPS27 VTCN1 RPL27A FTL GABRP TMSB4XP4 SPRR1B MDM2 CFAP47 TAB2 AC007969.1 AC099560.2 MAL2 CD24 COVID-19 patients BALF down Transcriptome sequencing data of the RNAs isolated from the bronchoalveolar lavage fluid (BALF) specimens of COVID-19 patients. MYH9 NUP210 UBB EMC1 FCGRT OS9 SYVN1 ATP6AP1 MVP NPTN ITGB1 LMAN2 TLE5 UPF1 CXCL16 TMBIM1 PFKL COLGALT1 HLA-B ZBTB7B ACAA1 NFATC2IP PHB2 CTSD NUCB1 ACADVL HGS CYB5R3 USP11 TMEM173 POR TRIM28 PES1 SIRPB2 GORASP1 FBP1 SPI1 SLC44A2 PLEC SLC9A6 SF1 CPT1A MGAT1 NAGLU MIF4GD TMEM109 TSPAN3 STIM1 SRRT TAGLN2 TMEM94 PLA2G15 RELT KHSRP C2CD2L ATP10A ITPK1 CD2BP2 SMARCD2 TMEM184B SYMPK MPZL2 POLG SLC12A9 CMTR1 IFFO1 BAX ANKRD13D TTC14 OGDH ANKRD52 PNPLA2 UNC93B1 PYGB KCNK6 ARHGAP30 ATP1A1 ARF3 MAN2B1 SEL1L NADSYN1 GPAT4 PRNP STT3A TMBIM6 ITGB2 CYBC1 SLCO2B1 ARID5A BANF1 TNFAIP2 PTGER4 LSP1 PRPS1 MYO1G PTPA NACC1 PDIA6 TMC6 ACER3 ARHGAP4 AQP3 TOMM40 TAOK2 LAIR1 GLYR1 RIPOR1 C1QC RMDN3 ENPP4 STMN1 ADCY7 PIEZO1 TMEM273 USF1 SIK2 RIC8A KSR1 MBD6 IL4R DDOST GSK3A PARP10 GPR107 MAPK8IP3 DDX41 ATG16L2 LGALS3BP DAZAP1 TOR1B TMEM127 UQCRC1 PDCD11 ZNF316 C15ORF39 DENND4B THBS1 RNASEL SH3TC1 TBC1D9B TMC8 SHC1 VPS37C PRKCSH INPPL1 ACSS1 MICAL1 RFX5 PARVG SLC3A2 ARHGEF10L ATG4B ITGAX TOR3A DPP7 TRPV2 PGD HS1BP3 CHID1 DHRS7 TM9SF3 LEMD2 STEAP3 VASP AKAP1 NUMA1 GSN C1QA XAB2 HBEGF H6PD GRINA TGOLN2 RPS6KA1 FLNA GART EMC10 AKT1 AP1M1 PLCB2 ZC3H7B PTK2B PNPLA6 APOL1 ALOX5 SRPRA TUBGCP6 PCNX3 LRRC25 LDB1 TBC1D2B GAA SEC24C SF3B4 USP19 FKBP8 SNRPB CD37 EMILIN2 HDAC6 GIGYF1 GNB2 LRP10 DDRGK1 VASH1 DNAJB2 SUMF2 ZDHHC7 VKORC1L1 MYADM CAD TGFBI PIGK GRK2 KHNYN SH3BP2 LEPROT CD81 QSOX1 TBC1D10B TYMP SPN SRSF9 MBD1 PROS1 CYBA PPP6R1 MAN1B1 RETREG2 CORO1B SHKBP1 PIP5K1C GPD1 DOK2 ADA2 BSDC1 ITGB5 BST2 GGA1 CIC LRP1 SPATA20 B3GNT7 RGS12 LMNA ITGAL PRAM1 UNC13D SDF4 PLOD1 EIF3B PLEKHO2 ZSWIM8 PSD4 URM1 SLC16A3 MAP3K11 ORAI2 EHBP1L1 NDST1 KCNAB2 ADGRE5 EDEM2 GANAB TYK2 SLC15A3 EFTUD2 SIN3B APH1A MARCO TBC1D10C HK1 UNC50 INF2 SMAD7 ITGAM APOL2 SELENON SLAMF8 TKT PDIA4 ARAP1 RARA TRIM65 SMARCD1 ITGA5 ITPKB CLUH HLA-E EMP3 TMED9 ARHGDIA NRP2 GRN TOLLIP CPVL HCAR2 WDR13 PPP6R2 HK3 CMTM6 ABCC3 SLC6A6 SNRNP70 RHBDD2 PPP1R12C DDB1 LTBR FBXO6 RHOB SLC1A5 ABHD2 ACLY SYNGR2 NCSTN SLC38A10 NFE2L1 GALNS ZYX SLC11A1 NCLN SCAMP2 MRC1 NLRP1 CD101 COVID-19 patients PBMC up Transcriptome sequencing data of the RNAs isolated from the peripheral blood mononuclear cells (PBMC) specimens of COVID-19 patients. MAOA TIMM8B CTSL C1ORF115 PCK2 TSPO HLA-DQA2 CXCL10 SIRPD YWHAG SLC16A8 PPT1 PKM ANXA2 ST14 ADAM9 KCNQ1 LAP3 CENPF JAK2 CIT F5 GPX1 FLT1 TCN2 BZW2 OAS1 COPB2 CTSD FN1 WASF1 PLD3 C11ORF74 SIL1 VSIG4 CAT AGPAT2 NDUFAF1 RPH3A FAM72B GGH PLP2 IL10 PGM2 FAH METTL7A GSTZ1 FZD5 MGAT1 ENO1 SDC1 AK4 NT5DC2 TNFSF10 SRGAP1 GASK1B MT1E CD180 CYBRD1 CKS2 PRDM1 TRIM7 HTRA1 TMIGD3 TPST1 IGLC2 PLA2G15 STT3A LAIR1 C1QC PGD STEAP3 C1QA GAA ADA2 MARCO HK1 SLC1A5 MRC1 SRD5A1 IGKV1-9 PLK1 CCT5 MYOF HERC2P4 SULT1A1 SLC38A7 CLTCL1 IGHV3-21 SLITRK4 IGKV1D-8 GLMP AK2 NET1 TIMP1 NDUFB5 FLVCR2 EXO1 PYCR1 GAS2L3 CEBPA-DT DHCR24 IGKV2-24 MYBL2 TOP2A IGHA2 ZNF100 ARHGAP31 AC018647.2 AL645608.2 DHRS4 AL139384.1 43891 PLEKHN1 TICRR IGLV2-8 PNP IGKJ1 AC067930.5 MRPL37 ERAL1 KIAA1958 IGKC C1ORF43 CES1P2 LINC02723 IGHV3-33 MILR1 AC098679.2 ZWINT AKIP1 CDCA8 GBGT1 IGHV4-61 VSIG10L P2RX4 CCNA2 IGHA1 SDC4 LMO2 CLSPN TK1 OCRL TROAP IGKV6-21 IGHV4-55 TWF2 ALDH1L2 EZH2 C3AR1 SAP30 C1ORF162 ATP5MC3 IGLV9-49 IGHV4-34 CAPG PAX8 NAIP IGHV3-22 MRPL12 LMNB1 CCNB2 MACC1 TUBG1 ME1 SMARCD3 PLBD1 SQOR IGHV3-15 IGKV2D-28 CEBPA ZBTB43 CHST13 SCARB2 IGKV1-8 NLN SLC35A5 CTSB CYFIP1 SNX32 IGHV3-66 XXYLT1 CHRNA7 FKBP9 IGHV2-5 IGLV2-5 C14ORF119 C5 IGHV4-39 GTSE1 CDKN3 UBE2C INKA1 AC004923.4 AREG IGHV3-73 IGKV2-40 CREG1 AC093627.4 FZD2 KNL1 NREP SLC16A1 IGHG4 AURKB HSD17B4 RAB20 LPL IGHG2 C5ORF66 KCNE1 HADHA GLRX E2F2 IGHV3-13 LINC01547 TK2 IGKV1D-37 IGHV1-2 ERI2 ADAM15 NEK2 KCNK13 SHCBP1 MARVELD1 HVCN1 ZNF366 MYO1E IGHG1 IGKV3-20 SCPEP1 MGST1 LDLR STS TMEM106A NOL3 AC140134.1 PSEN2 POMP KIF18B SPR KCTD3 JPH4 PHETA2 FRRS1 IGKV1-6 AC245014.3 NUF2 CDK5 AC009303.4 COQ5 IFI44 RNASE2 SEC11A MGME1 SPCS2P4 FLT3 MAPK6 DEPDC1B IGKV2D-29 EAF2 CDCA5 LINC02724 CLCN4 CES1P1 HMMR ANXA2P2 ADPRH IGHV3-30 ADAP2 AF111167.2 MCEMP1 MT1F KIAA0930 HTR7P1 SIGLEC12 SEC23B DDIT4 IGKV4-1 ANO5 NDUFS7 IGFBP2 IGLV2-18 RBBP8 IGHV3-7 SPAG5 TMEM38A FAM72D ELL2 FAM72A IGHV6-1 MSR1 MTCH2 ARHGAP29 LHFPL2 AL021155.5 AP2S1 ALCAM IGHJ2 TMTC1 TMTC2 GALNT2 HCCS AC007952.4 IGKV1-17 ITGA7 LGALS1 ERLIN1 STAC3 ANXA5 VDAC1 RAB13 ACVRL1 FKBP5 CORO2B LILRB5 IGKV1D-12 ARPIN BUB1B CTNND1 STARD13 TNFRSF17 OTOF MCM2 PDGFC IGHV3-43 RENBP WFDC1 IGHV3-62 AC008957.3 MRPL15 IGHJ5 KIF2C DERA CDC25A KIF14 ATP6V1F FUCA2 IGLV3-10 SLC39A11 MZB1 OPN3 KNSTRN IGKV2D-30 IGKV2D-40 NUDT16 OLAH UACA ASPM FH ACCS FGD2 SDHD IGKV1-37 HADHB IGKV1D-16 H1FX RNASE1 SERPINB10 TDRD9 MS4A4A AURKA METTL9 TIMP4 DLGAP5 NDUFAF3 TMEM150B ESPL1 AL022322.1 IGKV3D-20 CAPNS1 FADS1 IGLV1-40 BUB1 IGHJ4 AC130689.1 IGKV1-12 ZBTB32 SHROOM1 IGLV2-11 IGLV1-44 GPNMB IRF5 MAFG KIAA0895L RRM2 ALG14 SHMT1 ITSN1 IGHV1-24 SLC1A3 CDK1 SIGLEC11 SMAD1 FABP5P7 CLEC1B PAQR4 CTSZ MAFB CDC6 E2F1 BIRC5 BLVRA AL035411.1 IGHV4-28 AC138207.4 CBWD1 ORC1 PDSS1 IGHV1-69-2 C1QB POLQ Z93241.1 CES1 CHRFAM7A KIFC1 BCAT1 IGLV4-60 IGKV1-39 IGLV7-46 KIF4A NIBAN2 MPND TNFAIP8L2 AC100786.1 ADORA3 COMMD9 PRDX1 IGHJ6 CD163 IGHV4-59 SCIMP DHFRP1 KPTN IGHV3-49 EPSTI1 PAX8-AS1 NDUFS4 IGKV1-27 IGHV3-64 SAPCD2 SH2D4A ITGA1 CCT8 IGHV3-69-1 FCRL5 SIGLEC16 H1F0 HGF UAP1L1 IGKV3-15 MPDU1 CARD6 IGLV4-69 ROGDI LAMC1 TP53I3 SPRY2 GALK1 AC138207.9 EIF4G1 MCM10 IGLV7-43 DOCK1 RGS16 HSD17B10 IGLC3 AC068580.3 LINC00106 KIF15 TRPM2 RRAS SMTN IGKV5-2 IGHV5-51 PPARG IL18 MIR181A1HG FAM72C TMEM45A SNAPIN GSTO1 ASGR2 IGHV3-72 SLCO4A1 MYDGF GAPDH ADAMTS2 PRR11 LTA4H G6PC3 IGHV3-48 CDCA2 HEBP1 IGKV1-33 C2 IGHV4-4 EPHB2 GRB10 PPARGC1B NUS1P1 PDIA5 AC078819.1 APOL4 GLDC CLTA CALCRL LGALS3 ATP5PB IGLV1-47 IGHV3-74 PRRT4 GPAT2P1 IGLV1-36 IGLV2-28 RPL26L1 IGKJ4 KIF11 IGLJ3 LINC02785 NETO2 IGHV3-20 IGHV2-70D IGHV2-26 ACVR1B HDLBP IGHV2-70 SLFN11 ATP5F1B ABCD1 IGHV4-31 IGLV3-25 ECHDC3 IGKV3-7 IGKV3-11 AC253572.2 CCR2 SNX3 CD1A FAM198B-AS1 AL355922.1 CCDC200 NME1 BRCA2 NECTIN2 RMI1 IGKV2D-24 IGKV2-28 IGHV1-69 TPX2 ALOX15B MYO7A DUSP7 CDKN2B CLDN7 STIL AC090204.1 NRG1 CCNB1 IGLL5 AL844908.1 VPS25 IGKV2-30 HEXB PADI2 MERTK IGKV1-13 HLA-DRB6 ANLN IGHV1-46 NCAPH FER1L4 OLFML2A FAM20C NAGA OPLAH TMEM121B DEPP1 CBR1 DPYD EPS8 IGHGP IGKV2-26 GLDN SEPTIN10 IGHV3-23 CEP55 MMP19 SOWAHD TBL2 IGLV2-23 IGKV1D-39 IDH1 IGKV2-29 CDCA3 TEX2 ACO2 BATF2 PTPRO COX5A IGLV3-16 GRHPR CDC20 KIF23 IGLV3-19 IGLV10-54 IFI27L2 PKMYT1 SKA1 IGHG3 IGHV1-18 AMPH ANKLE1 UNC13B HJURP SNORD3C ALDH9A1 TRIP13 CLEC12B DYNLL1 CENPU OSTC HLA-DQB2 CENPW IGLV3-1 IGLV2-34 TTK IGHJ3 IGKV1-5 SEMA6B IGLV2-14 IGHV1-69D MICU1 GPER1 SYN2 PSMB2 FAM89A IGLV1-51 SNX8 PRDX3 HP IGKV3D-15 JCHAIN PAPSS1 C5ORF30 CDC42BPA SPATS2L ARHGAP23 MKI67 SH3PXD2B SMIM34B IGLV1-41 HPR LDHA ATP5F1C NTSR1 IGKV1D-33 TPI1 IGHV3-11 LIPA SORT1 CDC45 IGLV6-57 AC027601.6 ALDH4A1 RAPH1 SLC22A16 TRIM71 CERS6 PTGFRN KIF20A IGKV3D-11 DTL KCNMA1 RN7SL138P ARNTL2 TBC1D2 NRIP1 IGLV3-21 IGHV3-53 SPTLC2 ICAM5 MTHFD2 NKIRAS2 PRELID1 SLC43A3 SCD CLEC12A CD163L1 LINC00482 IGKV1-16 AC106865.1 YPEL4 MRPL51 RNASE3 IGKV1D-13 MAP3K6 AIMP2 PSMB7 RASGEF1B ANG NCAPG AC006946.1 AC012085.1 SLC9A7P1 GNPDA1 TYMS COVID-19 patients PBMC down Transcriptome sequencing data of the RNAs isolated from the peripheral blood mononuclear cells (PBMC) specimens of COVID-19 patients. ADAMTS1 SLC45A3 ENPP3 MME IFNG ITM2A NEO1 MYO6 RPS6KA5 ARL4D TSHZ2 AUTS2 IL5RA FP671120.7 AC079793.1 RN7SL1 C1ORF21 SLC4A4 SYTL2 MT-ND6 KIF21A ZNF91 RHOBTB3 CCDC80 SNORA73B RN7SL5P MALAT1 PRSS23 AGAP1 CCL4L2 ZBTB20 MMP23B GLI1 AC111000.4 ZNF365 AC020659.1 CCR3 AC087854.1 KIR2DL1 MPP6 B4GALNT3 LINC00944 LINC00869 ZNF574 B3GAT1 AJM1 CMTM2 BCL11B CORO6 ABCB1 LTBP4 SIGIRR ESRP2 LRRC43 CXCL8 IKZF2 BEGAIN CD247 KY AC026748.1 AP004608.1 AC068282.1 GPR68 GSTM2 LINC02384 LINC00513 RNU1-28P CA11 SIGLEC17P MIB2 CROCC2 LCNL1 RNVU1-7 BMERB1 SEMA4C SGCD MIR3648-2 NCR3 ESR2 C19ORF84 ENPP5 PDGFD GSTM1 YES1 CPA3 PLEKHA1 FAM160A1 RNU1-1 LRFN3 SH2D1B KLRG1 CRIP2 PER3 ARL4C RPL10P19 RNU1-3 RNU6-1010P EBF4 CEP126 ITGB8 IL7R AL035701.1 AC008533.1 ZNF600 PZP TNRC6C LINC02520 PTCH1 LINC00299 NBPF13P MTERF2 TPM2 NOG REELD1 RN7SL4P AKAP5 KLRB1 AP000936.3 AKT3 CHI3L1 LGR6 AL031283.1 CCN3 MLF1 MIR3648-1 RNU4-1 LINC002481 RORA-AS1 RNF165 METAZOA_SRP FAM169A AP001033.2 AC010894.5 FP671120.2 UPK3B TOPORS RN7SKP71 ZNF831 FGFRL1 LINC-PINT C16ORF54 CHIC1 AC068587.4 PRSS30P TMEM182 ZDHHC11B SNORA75 A2MP1 RHEBL1 OVCH1-AS1 AC009133.3 TPPP LGALS9C TRDC RNU1-2 TNFRSF10C LINC02458 GDF11 CTAGE6 U1 CCR9 CXCR2 ZBTB20-AS1 SH2D2A AL365203.2 MMP23A AC008033.3 LINC00612 Z94721.1 AC089984.2 ZFPM1 AC022973.3 AC020978.3 G0S2 AC104809.2 AL713852.1 CST7 SLC25A29 AL355987.4 AC010894.3 ZNF830 AKR1C3 MGAT4A LGALS9B KLF3-AS1 FAAHP1 MATK CTAGE9 LINC00298 RUNX3 PTGS2 LINC02084 PDZD4 FAM131B AC092652.2 A2M-AS1 MYH11 AL359636.2 KANK3 RNVU1-18 TRBV29-1 FP236383.5 ADGRB2 CDHR3 AC092645.1 ZNF528-AS1 LAMA2 TSPOAP1 COL18A1 Z94721.3 ARVCF HAR1A TRDJ1 AC006369.1 PTGDR2 SLC1A7 EEF1A1P3 AC131568.1 MS4A2 CABP4 PRDM8 ADORA2A-AS1 AC044849.1 ZFYVE28 MAGEE1 LINC00987 AC058791.1 CEP78 A2M HEATR4 NTRK1 SCARNA21 RNA5-8SN2 DRAXIN ANGPTL6 AC079781.5 AC016831.1 RNU1-27P TRIM51BP PTPRS CRYBG2 MSC YPEL1 S1PR5 AL359962.2 AL365475.1 CDKN1C SPON1 ST8SIA6 CRY1 CR392039.1 AC008735.2 NCALD 5_8S_RRNA EPHB1 BTG1P1 AC067945.3 LINC00402 CCL4 COL6A2 GATA3 ARHGEF35 AL359962.3 TCN1 KIF3A CAMK2N1 COLGALT2 KRT17P8 AKAP12 AP003717.4 CLC RAB11FIP5 TJP3 AL135818.1 SOX13 AC008440.1 RNA5-8SN1 PTGDR EGR3 LIM2 PBXIP1 AL499604.1 AC010168.2 AC016957.2 MYBL1 KLF2 NAP1L2 CACNA2D2 ZNF266 CLDND2 BMPR1A HRH4 CDHR1 FP236383.4 ZNF540 PRSS57 KRTAP5-AS1 RNA5-8SN3 SLC30A4 FP671120.6 FCRL6 IGFBP3 KIR3DL1 RNU1-4 AC026124.2 SCARNA5 AC009318.1 TFDP2 TSPYL1 TGFBR3 AC022217.3 NUAK1 EFNA5 CAMP LLGL2 SARS-CoV-2/Human Interactome Gene Set from Guzzi CD209 BCL2L1 EEF1A1 SFTPD FKBP1A EIF3F TMPRSS2 SMOC1 IRF3 KPNA2 DDX5 ACE2 YWHAE SLC46A3 RYBP BZW2 MARK3 HGS CLEC4G C11ORF74 CLEC4M PPIG PPIH MARK2 UBE2I PPIA FAHD1 N4BP2L2 C20ORF27 CAMLG CCHCR ZNF410 CHMP2B ATF5 NAE1 BCL2A1 RCAN3 IKBKB MKRN2 MCL1 PSMA2 CAV1 TPSAB1 NOMO3 ATP6V1G1 DDAH2 ALB C1ORF63 COX2 C7ORF36 TPSB2 RPS20 CHEK2 SGTA MNAT1 NCOA5 DEDD2 RNF128 BTF3 HOXC6 ENO1 EIF4B XPA FAM108A1 BRF1 PLEKHO1 DCTN2 OCIAD2 PFDN5 ISLR POLR2B LCP1 MIF4GD TBCB VKORC1 RPS17 MKRN3 ARL4D NMB LAS1L BCL2 NPHP3 HNRPA1 NDUFA10 C1ORF142 H2AFY2 TERF1 BAP1 BAT3 BCL2L2 SERPING1 ND4L SARS Perturbation 76 Down Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 1 SARS-CoV is the perturbagen used in this mouse study. CKM FABP1 TTN NPY KRT15 TMEM182 OBSCN DCT TMEM45B PON1 FABP4 COX7A1 KCNJ3 STMN3 MYH4 BVES DHRS7C KCNA6 TNNT2 ADIPOQ CASQ2 CIDEC MYOM2 CCL24 BPIFA1 ZNF442 RETN TRDN XIRP2 CCK EBF2 RYR2 METTL21C MYH6 CIDEA CA3 CYP1A1 IL36G MYL1 HSPB3 ANKRD33 TNNI3 BEX1 KCNA1 CFD S100A9 ENPP6 SRL FABP3 MYBPHL MYH8 ITGB1BP2 GSTA5 MYBPC3 VAT1L CSRP3 LCTL PLIN4 CDH26 TXLNB PLIN1 NPPA CYP2E1 PGAM2 MOGAT1 CCL17 MB DOC2B CST9L CKMT2 ALOX15 CD207 GPR113 MYL4 MYL7 THRSP SARS Perturbation 441 Up Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 2 SARS-CoV is the perturbagen used in this mouse study. FAM3B UHRF1 IL6 GIF CCL2 CCL5 UBD PDCD1 TNF AADAC CREB3L3 CXCL10 CYP4F2 CENPF IFNG IL12B TREM2 AKAP4 OAS1 FCGR2A FASLG STAT1 HLA-A PRIM1 BRCA1 IL12RB1 OASL CD8B CXCL2 IFNB1 CD8A ISG15 SEPT12 IL10 BCL2A1 CXCL6 IGSF6 CKS2 PRSS16 HIST1H2AC LCN2 HIST1H1D AGR2 AIF1 LAIR1 C1QC LGALS3BP C1QA LRRC25 TGFBI SPN SLAMF8 HLA-E GRN HK3 SLC11A1 PLK1 TIMP1 EXO1 GAS2L3 TOP2A TICRR CDCA8 CCNA2 CLSPN TK1 TROAP ALDH1L2 EZH2 C3AR1 LMNB1 CCNB2 GTSE1 CDKN3 UBE2C AURKB SHCBP1 KIF18B NUF2 IFI44 DEPDC1B CDCA5 HMMR SPAG5 MSR1 FKBP5 BUB1B MCM2 KIF2C KNSTRN ASPM AURKA DLGAP5 ESPL1 GPNMB RRM2 CDK1 MAFB CDC6 BIRC5 C1QB POLQ KIFC1 BCAT1 KIF4A SCIMP EPSTI1 SAPCD2 FCRL5 MCM10 RGS16 KIF15 PRR11 CDCA2 C2 KIF11 CCR2 TPX2 STIL CCNB1 ANLN CEP55 CDCA3 CDC20 KIF23 SKA1 ANKLE1 TRIP13 CENPW TTK MKI67 CDC45 KIF20A DTL MTHFD2 NCAPG GPR68 CST7 CABP4 CCL4 MYBL1 CHTF18 IL18RAP CKS1B DSCC1 HPGDS CD300C CCNE1 FOXM1 SLC26A4 CXCL13 SFRP1 MMP8 ATF3 DCK PRC1 PSRC1 CENPK CENPN GPR162 SAA1 SMC2 HCLS1 MEFV PTPN22 C11ORF82 CXCR3 LAT CD48 SLFN13 ARHGAP11A RSAD2 E2F8 UBE2T GPR65 OAS3 HIST1H2AJ SLC37A2 CD69 GSG2 KRT86 KLRC1 IL10RA CENPA MIS18BP1 IRF7 CFB FIGNL1 C1ORF112 KIAA1524 MXD3 GDF3 FBXO5 RGS1 MTFR2 PSTPIP1 PASK RAD54L SPIC STAG3 NKG7 CASC5 ESCO2 SPDL1 CD3G RAD54B ZNF705A EME1 FANCI ZBP1 BARD1 ASF1B APOD INSL6 KIF22 AOAH TCF19 CHEK1 RAD51 NSL1 SLAMF7 GINS2 IL18BP LCP2 PLA1A DUSP2 SIRPB1 PYCARD C17ORF53 SH2D1A GBP5 CKAP2L TNFRSF9 OCSTAMP CHAF1B CCL1 FAM64A IQGAP3 GATM MS4A7 PARPBP TAP1 RETNLB CTSW FAM83D PLD4 FANCD2 MMS22L C14ORF80 LILRB4 GFI1 SKA3 NCAPD2 BRIP1 SPC24 UPK3A MS4A6A SLC29A3 HELLS GPR84 CLEC5A IGJ LHX2 CXCR6 SGOL2 LCK CRTAM IL2RB EMR1 DBF4 KNTC1 CD160 OIP5 PPM1N CHIT1 ECT2 TACC3 ERCC6L NUSAP1 FCGR1A CKAP2 HIST1H2AD MCM5 LPXN GP2 PBK FSBP CENPI IFIT1 GPR176 FAM26F RACGAP1 AUNIP SPC25 KIF20B GTSF1 HIST1H2AE MELK CLEC4A SECTM1 ZWILCH XCL1 ARHGAP19 CD72 H2AFX ARHGEF39 CENPM SGOL1 TRAIP DEPDC1 MAD2L1 CENPP GPR31 CCNF NCAPG2 LRR1 SLAMF9 TNIP3 CCR5 HMGB2 HIST1H2AA GPR15 KNG1 CENPH FYB LY9 LY86 CLEC7A VAV1 FCGR2B IRG1 NDC80 TBX21 GZMK LAG3 B3GALT5 POLE INCENP DNASE1L3 IGF2BP3 CENPE NEIL3 KIAA0101 CCL13 CCL3L3 UBASH3A CTSS MASTL RAD51AP1 EOMES GPR171 GEN1 APOBEC1 FCER1G KHDC1L SELE FAM132B REG3G SYT12 ACKR1 PSAT1 DNPH1 LACC1 IFIT3 CD84 RTP4 SFT2D1 IFIT1B CHL1 CDT1 TLR7 PRSS22 ZRANB3 LRP8 CYP7B1 SLC7A8 HLA-F SLFN12L ADAMTS4 OAS2 CD86 C3 POLE2 PHF11 SIGLEC1 XAF1 HSF2BP CLEC6A CPN2 C9ORF169 CXCL3 CH25H PSMB8 CD274 APOL6 KCNJ10 CYP26B1 CALML5 COCH CCR1 GINS1 CXORF21 CA7 PALB2 GBP4 HOXC5 LOC101929327 FOLR2 TSHB BCL2L15 COL24A1 DHX58 CTSK FBXO39 CYBB PHF19 CD5L C1R IL1R2 KYNU GPR141 IL1RN SAA2-SAA4 TREX1 CHAF1A USP18 EFCAB11 CMPK2 CA13 IFIT2 ARL11 KIF18A CNGB3 EVI2A DPF1 KDM4D SYT10 IL2RA CCNE2 IFI16 XRCC3 SARS Perturbation 59 Down Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 2 SARS-CoV is the perturbagen used in this mouse study. TGM4 FABP1 FCER2 CYP2F1 FMO3 FAM83B CLEC12B PRDM8 NR5A1 PON1 DHRS7C KCNA6 CYP1A1 IL36G ANKRD33 BEX1 FABP3 MOGAT1 CCL17 MB DOC2B CST9L CD207 GPR113 ALAS2 CNR1 FSTL4 PAQR9 GDPD2 NTRK2 SUV420H2 HBB TRIM10 FAM181B ASGR1 SPACA7 SEPT3 SLC4A1 OSCAR C5ORF28 CHRM2 EMILIN3 NKPD1 MRGPRX3 PLA2G5 GRIA1 TEX40 C15ORF60 HEPACAM2 UPK2 C12ORF68 MDFI SNCA CD19 LRRC3B CHRDL1 NEUROG1 CDH16 PNLIPRP1 SARS Perturbation 430 Up Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 3 SARS-CoV is the perturbagen used in this mouse study. MISP IL1B UHRF1 IL6 CCL2 UBD PDCD1 TNF AADAC DDX58 CXCL10 IFITM3 SLU7 CYP4F2 CENPF IFNG IL12B TMEM54 TREM2 OAS1 CFP FCGR2A DMBT1 STAT1 HLA-A PRIM1 BRCA1 EIF2AK2 IL12RB1 OASL CXCL2 IFNB1 ISG15 SEPT12 CXCL6 IGSF6 S100A14 ITGA10 STEAP4 SPRR1A CKS2 PRSS16 HIST1H2AC SLPI LCN2 HIST1H1D AGR2 AIF1 LAIR1 C1QC LGALS3BP C1QA LRRC25 TGFBI ITGAM SLAMF8 GRN SLC11A1 PLK1 TIMP1 EXO1 PYCR1 GAS2L3 TOP2A TICRR CDCA8 CCNA2 CLSPN TK1 TROAP ALDH1L2 C3AR1 NAIP LMNB1 CCNB2 CHRNA7 GTSE1 CDKN3 UBE2C AURKB SHCBP1 KIF18B NUF2 IFI44 DEPDC1B CDCA5 HMMR SPAG5 MSR1 BUB1B MCM2 KIF2C KNSTRN ASPM AURKA DLGAP5 ESPL1 GPNMB RRM2 CDK1 MAFB CDC6 E2F1 BIRC5 ORC1 C1QB POLQ KIFC1 KIF4A ADORA3 SCIMP EPSTI1 SAPCD2 FCRL5 MCM10 RGS16 KIF15 PRR11 CDCA2 C2 KIF11 CCR2 TPX2 STIL CCNB1 ANLN CEP55 MMP19 CDCA3 CDC20 KIF23 SKA1 ANKLE1 TRIP13 CENPW TTK MKI67 CDC45 KIF20A DTL MTHFD2 NCAPG CCL4 CHTF18 CKS1B DSCC1 HPGDS CD300C CCNE1 FOXM1 SLC26A4 CXCL13 SFRP1 ALPL MMP8 ATF3 HPX DCK PRC1 PSRC1 CENPK CENPN GPR162 SAA1 SMC2 HCLS1 MEFV C11ORF82 CXCR3 SLFN13 ARHGAP11A RSAD2 CDC25C E2F8 UBE2T GPR65 OAS3 HIST1H2AJ SLC37A2 GSG2 IL10RA CENPA MIS18BP1 IRF7 CFB FIGNL1 C1ORF112 KIAA1524 MXD3 GDF3 RGS1 MTFR2 PASK RAD54L SPIC STAG3 CASC5 ESCO2 SPDL1 RAD54B ZNF705A EME1 FANCI ZBP1 BARD1 ASF1B APOD KIF22 AOAH TCF19 CHEK1 RAD51 NSL1 SLAMF7 GINS2 IL18BP PLA1A SIRPB1 C17ORF53 GBP5 CKAP2L TNFRSF9 OCSTAMP CHAF1B CCL1 FAM64A IQGAP3 GATM MS4A7 PARPBP TAP1 RETNLB FAM83D PLD4 FANCD2 MMS22L C14ORF80 LILRB4 SKA3 NCAPD2 BRIP1 SPC24 UPK3A MS4A6A SLC29A3 HELLS GPR84 CLEC5A IGJ LHX2 SGOL2 EMR1 KNTC1 OIP5 CHIT1 ECT2 TACC3 ERCC6L NUSAP1 FCGR1A CKAP2 HIST1H2AD MCM5 LPXN PBK FSBP CENPI IFIT1 GPR176 FAM26F RACGAP1 AUNIP SPC25 KIF20B GTSF1 HIST1H2AE MELK CLEC4A SECTM1 ZWILCH XCL1 CD72 H2AFX ARHGEF39 CENPM SGOL1 TRAIP DEPDC1 MAD2L1 CENPP GPR31 CCNF NCAPG2 LRR1 SLAMF9 CCR5 HIST1H2AA KNG1 CENPH LY9 LY86 CLEC7A FCGR2B IRG1 NDC80 LAG3 POLE INCENP CENPE NEIL3 KIAA0101 CCL13 CCL3L3 CTSS MASTL RAD51AP1 GEN1 APOBEC1 FCER1G ZNF442 PGAM2 ALOX15 KHDC1L SELE FAM132B REG3G SYT12 ACKR1 PSAT1 DNPH1 LACC1 IFIT3 RTP4 IFIT1B CHL1 CDT1 TLR7 PRSS22 ZRANB3 CYP7B1 SLC7A8 HLA-F SLFN12L ADAMTS4 OAS2 C3 POLE2 PHF11 SIGLEC1 XAF1 HSF2BP CLEC6A CPN2 C9ORF169 CXCL3 CH25H APOL6 CCR1 GINS1 GBP4 LOC101929327 BCL2L15 COL24A1 DHX58 CTSK FBXO39 CYBB PHF19 CD5L C1R IL1R2 GPR141 IL1RN SAA2-SAA4 TREX1 CHAF1A USP18 EFCAB11 CMPK2 CA13 IFIT2 KIF18A CNGB3 EVI2A DPF1 IL2RA CCNE2 IFI16 XRCC3 CD300LF NEFH CLEC4E PTAFR COL3A1 MMP12 DHFR MAB21L3 TGM1 HCRT SUCNR1 BRINP1 PLAC8 NAV3 TMEM52B TIMELESS APOF FGL1 ALDH1B1 PCDH20 FABP7 CD177 PREP UNG PDYN HERC6 NPRL3 NMRAL1 AAK1 KIZ CLEC4D IFIH1 TNFAIP6 MLKL CPXM1 CCDC18 TMEM143 HAS3 LGMN AMBP STAT2 SARS Perturbation 70 Down Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 3 SARS-CoV is the perturbagen used in this mouse study. TGM4 FABP1 AASS CDK5RAP1 CYP2F1 SCGB3A1 FMO3 FAM83B CLEC12B LTBP4 AXIN2 WNT10B MESP1 NR5A1 DACT2 PON1 BEX1 MOGAT1 CCL17 CST9L CD207 GPR113 ALAS2 PAQR9 GDPD2 SUV420H2 HBB TRIM10 ASGR1 SPACA7 SEPT3 SLC4A1 CHRM2 EMILIN3 PLA2G5 GRIA1 C15ORF60 HEPACAM2 UPK2 C12ORF68 SNCA CHRDL1 NEUROG1 CDH16 ACOXL NRN1 STON1 RNASE4 CACNA1G CYP4F8 DCDC5 EPPIN-WFDC6 AKNAD1 CNPY1 GNAL OR4C12 S100G SMIM23 CCDC129 CST8 SFTPB LGI3 HMGCS2 SNX22 SLC32A1 LYZL4 IGFBP6 RAMP1 CPNE5 HBG2 SARS Perturbation 357 Up Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 4 SARS-CoV is the perturbagen used in this mouse study. MISP IL1B IL6 GDF15 CCL2 CCL5 EGR1 UBD PDCD1 LOX TMPRSS3 NMI TNF DDX58 IL1A CXCL10 IFITM3 TRIM15 UNC93A IFNG IL12B IFNL3 OAS1 AOC1 PTX3 DMBT1 STAT1 TRIM25 EIF2AK2 IL12RB1 CLCA1 OASL CXCL2 IFNB1 ISG15 NTS IL10 MYD88 NPY ALDH1A3 TMC5 CXCL6 S100A14 CD180 STEAP4 SPRR1A TACSTD2 ISG20 PLA2G7 LCN2 AGR2 AIF1 DHRS9 ARID5A PARP10 LGALS3BP THBS1 TOR3A LRRC25 TGFBI SLC15A3 SLAMF8 GRN HCAR2 HK3 TIMP1 PNP C3AR1 CHRNA7 AREG RAB20 TMEM106A IFI44 MSR1 IRF5 MAFB SCIMP EPSTI1 MCM10 RGS16 SLCO4A1 C2 GLDC TPX2 MMP19 BATF2 TTK MTHFD2 LGALS9B CABP4 A2M CCL4 SLC2A6 CDKN1A GADD45G MMP25 GJB5 SLC26A4 CXCL13 SFRP1 ALPL MMP3 MMP8 ATF3 HPX DCK BCL3 HELZ2 OGFR SAA1 MEFV SLFN13 RSAD2 GPR65 OAS3 SLC37A2 CD69 IDO1 IRF7 CFB RGS1 PSTPIP1 SPIC ZNF705A ZBP1 APOD AOAH SLAMF7 NLRC5 IL18BP PLA1A DUSP2 SIRPB1 GBP5 TNFRSF9 OCSTAMP MS4A7 TAP1 RETNLB LILRB4 CCL20 MS4A6A GPR84 CLEC5A LHX2 CHIT1 FCGR1A IFIT1 FAM26F GTSF1 SECTM1 XCL1 CD72 GPR31 TNIP3 CCR5 GPR15 KNG1 IRG1 GZMK LAG3 DNASE1L3 CCL13 CCL3L3 APOBEC1 FCER1G DOC2B SELE SYT12 ACKR1 PSAT1 LACC1 IFIT3 RTP4 IFIT1B CHL1 PRSS22 CYP7B1 SLC7A8 SLFN12L ADAMTS4 OAS2 CD86 PHF11 SIGLEC1 XAF1 C9ORF169 CXCL3 CH25H PSMB8 CD274 APOL6 COCH CXORF21 GBP4 LOC101929327 BCL2L15 DHX58 FBXO39 IL1R2 GPR141 IL1RN SAA2-SAA4 TREX1 USP18 CMPK2 CA13 IFIT2 CNGB3 EVI2A IFI16 MRGPRX3 CLEC4E PTAFR MAB21L3 TGM1 PLAC8 NAV3 APOF ALDH1B1 FABP7 CD177 PDYN HERC6 CLEC4D IFIH1 TNFAIP6 MLKL AMBP STAT2 PML IL5 PLEKHA4 JPH3 FGG KL VCAN TCIRG1 CLDN2 TINAGL1 SOCS3 CCL11 ARSI TREM1 TEX19 AMIGO3 NFKBIE DIO2 ADAR NAMPT RNASE10 TNFRSF12A TIFA RASA4 GBP2 MCOLN2 NT5C3A GLIPR2 RHCG LYPD8 PARP9 PSAPL1 PARP12 ARC SAMD9L GCH1 HSH2D ADM MUC5B TMEM171 NFIL3 F9 XDH IFNA4 SLC17A6 PTGES LRRC4 BTBD16 KCTD19 SLC7A11 MORC1 DAXX PIM1 GBP6 SELP SMC1B HPSE CASP4 NOD2 SERPINA3 TARM1 FAP LIPG IL4I1 INHBA BASP1 C20ORF141 RNF213 AIM1 ASAP3 IFI35 SLC39A14 PARP14 DDX4 C11ORF85 SLC25A22 FOSL1 PTPRT HAS2 CALCB SOCS1 HAND2 TRIM6 RASL10B OR2V1 TRAFD1 GPR35 IRGM PCDH10 SAMHD1 F3 HAS1 CCL19 KLHDC8A ARG1 C5AR1 BTBD17 CSTA EGR4 PPA1 MITD1 PARP11 GFPT2 ARNTL UBE2L6 TNNI1 ANGPTL4 NRIP3 AIDA TLR3 C19ORF80 ZNF536 IL24 DRD4 HAP1 PLAU UBA7 GCKR GBP7 PPY FST NINJ2 APOC2 PDE2A WARS SP110 CSF3 SARS Perturbation 143 Down Genes from GEN3VA Mouse Lung; Accession: GSE68820 ; Platform: GPL7202 ; Entry 4 SARS-CoV is the perturbagen used in this mouse study. SPTB TINAG GPT FABP1 ENTPD8 SLC15A1 AASS CHP2 SMO METTL7A FN3K GPR155 OCIAD2 CYP2F1 KRT5 VEPH1 HLF FMO3 FREM2 KIAA1324 PTGFR KRT15 ALOX5 CES1 CD163 CPA3 PER3 YPEL1 COLGALT2 WIF1 SFRP2 WNT10B DIXDC1 WNT2 SHISA2 MAP2K6 UPK3A TMEM45B PON1 KCNJ3 KCNA6 ADIPOQ CIDEC RETN CA3 BEX1 LCTL CDH26 CYP2E1 THRSP CPN2 TSHB SEPT3 HEPACAM2 CDH16 PNLIPRP1 NRN1 CNPY1 S100G CCDC129 CST8 LGI3 HMGCS2 SLC4A5 ZNF711 SCN1A PSD2 PABPC4L HPCAL4 SCUBE2 GAL3ST4 SNAI2 EFNA2 KCNIP4 GLT8D2 NDP EPHX1 MAMDC2 P2RX6 GPR34 HCN1 ITGA8 HSBP1L1 SLC7A10 PGPEP1L LGALS12 ATP13A4 CDH22 CTHRC1 PIPOX IGDCC4 DGKB GDF10 ACKR4 NEGR1 ATP2B2 TMEM35 IQCH EPHA1 ANGPTL2 CHST8 MYH7 CALML3 ZNF704 SIGLEC8 PPP2R2C GDF1 MICALCL RTN2 KAZALD1 SCN3A WBSCR17 C1ORF56 PCOLCE2 SPAG4 SVOPL CPB1 NETO1 RIMKLB TRIL NAP1L5 GSG1L EPHB6 LRRC17 SLC3A1 TNNC2 LRAT DBP SPACA1 CELF5 CD59 TMED6 INMT C1QTNF3 SORD CNGA1 VSTM2A RBP7 SLC6A15 DDC SLC35F3 UCP3 SCN7A SARS Perturbation 320 Up Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 1 SARS-CoV is the perturbagen used in this mouse study. EEF1A1 MAPK3 HSP90AB1 FKBP1A EGR1 CTDSP1 SPTAN1 FGF23 MAP1LC3A PPP2R1A DDX5 UBC YWHAZ CXCL10 IFITM3 ANXA3 TOR1AIP1 SEPP1 TMBIM1 ZCRB1 YWHAE HSPB1 TUBA1A OAS1 APOA4 RDX RELA NCKAP5 ACE STAT1 TRIM25 IFITM2 B2M RAB7A OASL GNB1 MSN PLS3 FERMT2 SLC44A2 ARHGEF12 VAMP8 EI24 KDR AFAP1L1 PTTG1IP ATF5 CAV1 ATP6V1G1 ALB KRT7 RPLP2 CEBPD RPS12 TPT1 HOPX PNRC1 SLC25A4 TJP1 ISG20 KRT8 FTL STMN1 GSK3A SNRPB GNB2 SRSF9 ARHGDIA GRN RHOB LMO2 IFI44 ANXA5 CAPNS1 RRAS CALCRL SNX3 CDKN2B AKAP5 LGALS9B AKAP12 KLF2 ZFP36L1 CTNNA1 RPS2 ACTB JUP KRT80 MYH14 SOX17 EDNRB GABARAPL1 SLC9A3R2 HNRNPK MAFK HELZ2 RSAD2 IRF7 IFIT1 TNNT2 NPPA MB MYL4 MYL7 IFIT3 RTP4 IFIT1B PHF11 XAF1 GBP4 LOC101929327 USP18 CMPK2 IFIT2 IFI16 PLAC8 IFIH1 SOCS3 GBP2 PARP9 PARP12 SAMD9L XDH DAXX GBP6 RNF213 IFI35 PARP14 IRGM SAMHD1 GBP7 SCN7A ACTC1 TSC22D1 IRF2 AHR PSME1 TMCC2 TTYH3 BTG2 CAV2 FTH1 DPYSL2 ACER2 TFG EHD4 CLIC4 RNF7 SRSF4 ETS1 PCBP2 PSENEN PSME2 RPL28 AARD SHANK3 GPR116 BMPR2 THBD GNAI2 COASY RPS28 SPTSSA PFN1 KLF4 UQCRB CYP4B1 TSPAN13 AKAP2 PTGES3 TOX2 ZFP36 NUFIP1 LASP1 CYR61 TNS1 SELK CD200 LAMTOR3 FAM73B SHISA5 COX6A2 RPL8 CDH5 SEPT4 DGKZ IER2 CNN2 YBX1 CYTH3 LY6E EPAS1 LRFN4 TNNC1 IER3 HNRNPM TUBA1B FOS TMA7 IGFBP4 ACTG1 AKR1A1 YBX3 MYOZ2 BMP6 ATP6V0C MAP1LC3B SNRK PLTP IRF1 HMGN1 SMDT1 PSMB10 CTBP1 ATP5G3 SGK1 GRASP CRYAB MYL2 TEK BAG1 RASGRP3 PPP1CB UNC45B MYL12B CHMP4B RAC1 EIF3G DUSP1 SDHB FAM129B TGM2 FMO1 ELOVL5 GSTM5 TMEM100 ADIPOR1 PEBP1 COX17 THRA HPCAL1 CYYR1 RNF187 EEF2 HMGCS1 RHOG R3HDM2 TMCC3 SIPA1 CAPZB PLVAP MYL12A TXNIP TXN ICAM1 DTX3L NFKBIA TPPP3 FOXF1 ID3 RAMP2 SPARC PTPRM SYF2 RABGGTA ATP5J ARL2BP SMAD6 FGD5 EIF2S3 ATP6V0E1 CDC42EP1 GSTP1 BGN CLIC3 KLHL5 ANAPC13 EGFL7 CLDN18 ST5 HPGD PCBP1 GLTP MRFAP1 GATA2 PTPRB HIST1H2BI IRF9 UBL3 RHEB MORF4L2 RIPPLY3 ITM2B JUNB CLIC5 TSPAN7 NDUFA3 TMEM204 U2AF2 SMAGP PSMB9 RAPGEF2 CLEC14A PXDC1 GBP3 GDPD3 DAZAP2 JUN AGER MED18 C9ORF69 SOX18 RPS23 MYH1 TJP2 CHCHD2 CLDN5 CA2 SEMA3C RBMS1 SARS Perturbation 180 Down Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 1 SARS-CoV is the perturbagen used in this mouse study. RPS27A SFTPD RPL12 RPL13 NPC2 DPEP1 YWHAB ENPEP ERP44 ATP1B1 MFGE8 NPM1 CAT PPIA MXRA8 RPS17 SERPING1 RPL37A RPS26 CYP2F1 RPL21 CP RGS2 RPL27 HLF RPS15A RPS24 SCGB3A1 RPL38 WFDC2 RPL23 RPL13A RPSA RPS15 RPS13 RPS18 RPL19 RPS29 RPL7A FMO2 RPL11 RPS14 RPS7 RPL7 RPL27A TAGLN2 CD81 CCT5 CYFIP1 FKBP9 C5 NREP MGST1 ALCAM LGALS1 CES1 HP SCD PKD2 MPEG1 EGFL6 LAMP1 F2R HLA-DRB5 DVL1 CTSC HSD11B1 IGJ CTSS PON1 FABP4 BPIFA1 COL3A1 RNASE4 S100G SFTPB MAMDC2 ITGA8 PCOLCE2 LRAT DBP SLC34A2 SH3BGRL CTGF FABP5 DRAM1 NPNT C16ORF90 COX7A2L RPL3 VEGFA RPLP0 RPL5 RBBP7 RPS19 RABL2A UQCRC2 NGFRAP1 P4HB PDGFRA OGN POLDIP3 DMKN SH2B1 EIF3E SFTPA1 FBXO16 CYB5A WBP5 SFTPC UCP1 SCGB3A2 GNG10 SPECC1L FIGF H2AFZ S100A4 VIMP BCAP31 CST3 MAT2A COX7A2 CRIP1 PLIN2 DCN GPAM ADAMTS15 CPNE7 AMMECR1L EFEMP1 EIF3I CCT2 EEF1B2 RPS4Y1 RPL10A SLC36A2 SNX17 MDH2 SCGB1A1 ITM2C LUC7L3 HLA-DQB1 BTG1 RPL10 C14ORF166 SLC16A11 LYZ SERPINE2 SNRPD2 RPL26 RPS5 C2ORF53 LAMP2 LIMCH1 NACA RPS21 DPT CTSH PDE5A ALDH1A1 GDI2 HLA-DQA1 ACAT2 EIF3K ZNF780A CHIA NR1D2 RPL22 RPS10 PPIB RPN1 TAF7L MYH10 PRRG3 NDUFA13 TAGLN GABARAP RPL4 MGP KLF9 SARS Perturbation; 254 Up Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 2 SARS-CoV is the perturbagen used in this mouse study. EEF1A1 MAPK3 HSP90AB1 FKBP1A CCL5 SUMO2 EGR1 SQSTM1 NMI TSPO UBC RHOA CXCL10 IFITM3 ANXA3 TPM3 TOR1AIP1 SEPP1 UBA1 HSPB1 AP2M1 TUBA1A GPX1 OAS1 COL4A2 RELA STAT1 TRIM25 HLA-A IFITM2 B2M FAU OASL MSN YWHAH PPIA VAMP8 KDR ATF5 PSMA2 CAV1 KRT18 KRT7 RPLP2 TPT1 HOPX COX6A1 ISG20 RPL7A CCND1 FTL TMBIM6 LGALS3BP SNRPB GNB2 SRSF9 CYBA EMP3 ARHGDIA GRN PNP LMO2 POMP IFI44 ANXA5 CAPNS1 RRAS LGALS3 SNX3 DYNLL1 LDHA LGALS9B KLF2 CDKN1A RPS2 MANF ACTB KRT80 ATF3 SLC9A3R2 MAPK11 MAFK HELZ2 CD226 RSAD2 IDO1 IRF7 ZBP1 APOD FCGR1A IFIT1 CCL13 CTSS FCER1G TNNT2 NPPA MYL7 IFIT3 RTP4 IFIT1B PHF11 XAF1 CXCL3 PSMB8 CD274 GBP4 USP18 CMPK2 IFIT2 IFI16 PLAC8 IFIH1 GBP2 PARP9 PARP12 SAMD9L XDH DAXX GBP6 BASP1 RNF213 IFI35 PARP14 TRAFD1 IRGM SAMHD1 GBP7 WARS ACTC1 PSME1 TMCC2 FTH1 EHD4 CLIC4 PSENEN PSME2 GPR116 GNAI2 PFN1 UQCRB CYP4B1 AKAP2 ZFP36 SELK CD200 SHISA5 CNN2 YBX1 LY6E EPAS1 TNNC1 IER3 TUBA1B FOS ACTG1 AKR1A1 MYOZ2 ATP6V0C PLTP IRF1 SMDT1 PSMB10 ATP5G3 CRYAB MYL2 TEK BAG1 MYL12B CHMP4B RAC1 EIF3G DUSP1 SDHB FAM129B TGM2 HPCAL1 EEF2 PLVAP MYL12A TXN ICAM1 DTX3L ID3 RAMP2 SPARC SYF2 ATP5J GSTP1 CLIC3 EGFL7 CLDN18 PCBP1 RHEB ITM2B CLIC5 TSPAN7 NDUFA3 PSMB9 GBP3 GDPD3 DAZAP2 JUN AGER SOX18 CLDN5 CA2 GABARAP MGP LYVE1 PSMB6 PSMC2 COX8A IFI44L ARPC3 NDUFS3 PRDX5 VPS28 ARPC2 PRX NME2 BCL6B EIF5A ARL6IP4 C19ORF43 PPP1CA PLSCR3 ATP5D LITAF VDAC2 DNAJC8 DRAP1 MRPL20 PSMB5 RNF114 C11ORF96 RAP1B PFDN6 ISCU C1QBP TRAPPC6B LAPTM4A SERPINB9 PSMD3 PISD S100A6 TUBB NDUFS6 NUPR1 TMEM176B TAPBP IHH SH3BGRL3 TMEM160 PPP1R14A SARS Perturbation; 246 Down Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 2 SARS-CoV is the perturbagen used in this mouse study. RPS27A TBCA SFTPD EIF3F RPL13 DPEP1 YWHAB ATP6AP2 TTN ENPEP ATP1B1 PABPC1 NPM1 PLS3 CAT PAICS NAP1L1 MDH1 SCP2 METTL7A NAE1 MCL1 RPS20 RPS17 RPL37A RPS26 CYP2F1 RPL21 RPL9 RGS2 RPS12 RPS11 RPL14 RPL27 RPS15A RPS24 SCGB3A1 RPL6 RPS8 RPL38 SMPDL3A WFDC2 ADH1C RPL23 RPL13A RPS25 RPSA RPS15 DYNLRB2 RPS13 RPS18 RPS29 FMO2 RPL11 RPS14 RPS7 RPL7 RPL27A TMEM109 GSN MYADM CD81 CCT5 NDUFB5 FKBP9 C5 NREP LPL MGST1 ALCAM CES1 PRDX1 HP SCD G0S2 HINT1 PKD2 SPINT2 SPARCL1 LAMP1 F2R HNRNPH1 HNRNPK DVL1 CTSC HSD11B1 PON1 FABP4 COL3A1 RNASE4 SFTPB MAMDC2 ITGA8 PCOLCE2 LRAT DBP INMT SCN7A TSC22D1 RPS28 SPTSSA PPP1CB FMO1 BGN TMEM204 MYH1 CHCHD2 SLC34A2 SH3BGRL CTGF FABP5 DRAM1 NPNT COX7A2L RPL3 VEGFA RPL5 RBBP7 RPS19 RABL2A UQCRC2 PDGFRA OGN EIF3E SFTPA1 CYB5A WBP5 SFTPC SCGB3A2 GNG10 SPECC1L H2AFZ VIMP MAT2A COX7A2 DCN GPAM ADAMTS15 EFEMP1 EIF3I EEF1B2 RPS4Y1 RPL10A SNX17 SCGB1A1 ITM2C LUC7L3 BTG1 RPL10 C14ORF166 LYZ SERPINE2 RPL26 RPS5 LIMCH1 NACA RPS21 DPT PDE5A ALDH1A1 GDI2 HLA-DQA1 ACAT2 CHIA RPL22 RPS10 PPIB MYH10 PRRG3 RPL4 KLF9 SLC12A2 PTP4A2 HNRNPUL1 ABRACL MORF4L1 GLUL QDPR PAIP2 CCKAR TM9SF2 DDR2 GSTA3 MATR3 CCNI CCT4 JUND IMPAD1 CETN2 GIMAP8 NSMF LTBP3 COX4I1 C6ORF57 ATP5H EID1 NDUFB3 NDUFB11 SHFM1 KDELR1 BNIP3 HIPK3 RPL18 PLXDC2 RHOQ ARRDC3 PABPN1 TCF21 HCFC1R1 BRK1 DDX3X VIM EPC2 TP53INP1 FNTA PDCD4 ZMYND11 PTGR1 MBNL1 TMEM50B CD74 RPL35 TSC22D3 SRP14 SP3 FHL1 SNRNP48 DYNLT3 SMIM15 NDFIP1 RPS9 ITPRIPL2 PCNP SDPR CNBP DHX15 RPL15 RBMS3 LRRC58 SH3PXD2A TOMM20 HADH DDX17 SEPT7 OAZ1 C10ORF10 SARS Perturbation; Up Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 3 SARS-CoV is the perturbagen used in this mouse study. MYH9 RPS27A MAPK3 HSP90AB1 FKBP1A HSPA5 APLNR EGR1 SPTAN1 MAP1LC3A PPP2R1A HIST1H1C TSPO UBC RPL13 NPC2 IFITM3 ANXA3 TPM3 ATP6AP2 SEPP1 TMBIM1 ZCRB1 COL4A1 ANXA2 ACSL5 FURIN GNG5 HSPB1 HSP90AA1 TUBA1A ACAA1 TCN2 COL4A2 TUBA4A HLA-A IFITM2 B2M MFGE8 CNDP2 REEP5 HSPA8 ARF6 SLC44A2 BRI3 CNTD1 AFAP1L1 PTTG1IP NDUFB6 MCL1 CAV1 ATP6V1G1 ALB DCTN2 BPIFB1 RPL37A KRT18 KRT7 RPLP2 CEBPD RPS12 ARL3 RPL14 AQP5 HOPX RPS8 PKP4 COX6A1 RPSA SLPI GPRC5A EMP2 TMEM109 TMBIM6 ITGB2 STMN1 PGD GSN GRINA EMC10 SNRPB CYBA TKT ARHGDIA GRN SYNGR2 MARVELD1 IFI44 DDIT4 NDUFS7 ANXA5 METTL9 IL18 LGALS3 SNX3 NME1 COX5A DYNLL1 AKAP5 KLF2 CDKN1A HINT1 CTNNA1 RPS2 MANF MPEG1 ACTB SPINT2 DSP SCNN1A KRT80 MYH14 CLU LAMP1 F2R SLC9A3R2 RAP1A HNRNPK HLA-DRB5 PREB CEBPB HELZ2 IRF7 IGJ CORO1A CLEC7A CTSS MYH6 MYL7 IFIT3 RTP4 IFIT1B C3 PHF11 XAF1 PLAC8 XDH FAP IFI35 TTYH3 RPL28 GPR116 THBD GNAI2 RPS28 KLF4 UQCRB CYP4B1 TSPAN13 PTGES3 TOX2 ZFP36 CYR61 SHISA5 DGKZ IER2 CNN2 YBX1 LY6E EPAS1 IER3 TUBA1B FOS TMA7 ACTG1 AKR1A1 YBX3 ATP6V0C MAP1LC3B PLTP HMGN1 CRYAB MYL12B CHMP4B EIF3G DUSP1 TGM2 FMO1 PEBP1 COX17 HPCAL1 RNF187 PLVAP MYL12A TXNIP TXN ICAM1 NFKBIA RAMP2 ATP6V0E1 GSTP1 EGFL7 PCBP1 GLTP MRFAP1 GATA2 HIST1H2BI UBL3 RIPPLY3 ITM2B JUNB TMEM204 U2AF2 PXDC1 GDPD3 JUN AGER TJP2 CHCHD2 CLDN5 VIMP BCAP31 CST3 MAT2A COX7A2 SNX17 MDH2 ITM2C HLA-DQB1 RPS21 HLA-DQA1 PPIB RPN1 NDUFA13 LYVE1 PSMC2 ARPC2 PRX NME2 PPP1CA ATP5D C1QBP TMEM176B SH3BGRL3 TMEM160 QDPR JUND NSMF LTBP3 COX4I1 NDUFB11 KDELR1 PABPN1 HCFC1R1 BRK1 VIM CD74 RPL35 TSC22D3 SRP14 NDFIP1 ITPRIPL2 OAZ1 C10ORF10 NDUFA5 EFNB1 IL3RA PRPF19 CHST1 NDUFB7 ESAM FDX1 PEX6 RGCC LYPLA2 PSMB4 SAP30L H2AFY RPL18A NPR3 FAM189A2 CDK16 PLEKHG2 FUCA1 ICAM2 CA4 SEPW1 EIF4E3 STUB1 JTB ADRM1 TYROBP NDUFA2 ZBTB16 CHORDC1 IFI30 RP9 CAMTA2 SOD1 LAMTOR1 EMC3 RAN BMS1 CSF1R PRMT2 GIMAP4 CCT3 KRTCAP2 ATF4 EVA1B TALDO1 CD97 CRELD2 PIM3 DHX30 SLC39A1 HSPH1 ROMO1 CALR NDUFV3 TRMT112 PSAP ACTA1 S100A16 LIMS2 KLHDC3 NDUFC1 TEX261 PQBP1 HN1 ATP6V0B MRPL28 FXYD5 AQP1 CFL1 LIMD2 HEXA FAM107A ARF1 LAPTM5 FAM134A MPC2 CDIPT FAM53B C19ORF59 SMIM22 RAPGEF3 BLMH RNPS1 MXD4 ADAMTSL2 COX6B1 JDP2 ERRFI1 PIGQ NDUFA1 RAB11A GPI CTU2 RBBP4 CCNL1 TUBB2A PDPN IL2RG DNAJA1 TMEM259 DNAJB1 MYEOV2 IGFBP7 RTKN2 PSMA6 FHAD1 CYP2B6 EHD1 MKNK2 ALOX5AP SARS Perturbation; 134 Down Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 3 SARS-CoV is the perturbagen used in this mouse study. SFTPD CSDE1 ENPEP ATP1B1 FAU PABPC1 NPM1 PPIA NAP1L1 METTL7A RPS17 RPS26 CYP2F1 RPL21 RGS2 HLF RPS24 TPT1 NFIB WFDC2 ADH1C RPL23 RPS15 DYNLRB2 TJP1 RPS18 RPL19 RPL7A FMO2 RPL11 RPS14 RPS7 RPL7 C5 NREP MGST1 LGALS1 CES1 HP GSTM1 AKAP12 PKD2 HSD11B1 PON1 FABP4 COL3A1 RNASE4 MAMDC2 ITGA8 PCOLCE2 LRAT DBP INMT ATP5G3 RPS23 MYH1 SLC34A2 SH3BGRL DRAM1 COX7A2L RPL3 VEGFA RPLP0 RPS19 RABL2A UQCRC2 OGN EIF3E FBXO16 SCGB3A2 SPECC1L CRIP1 DCN EIF3I EEF1B2 RPL10A SCGB1A1 RPL10 LYZ RPS5 C2ORF53 LIMCH1 NACA DPT PDE5A ALDH1A1 ZNF780A CHIA NR1D2 RPL22 MYH10 TAGLN MGP PISD NUPR1 CCKAR DDR2 CCNI BNIP3 DDX3X PTGR1 FHL1 LRRC58 SH3PXD2A TCP11 FEZ2 KCNA7 DSTN CAPZA2 MYLK RPL36AL WNK1 LBH TNS3 MYLIP NDUFA6 AGO1 RBM3 FNDC3B PSKH1 NAB1 CCDC57 FSTL1 VDAC3 MBLAC1 STK38 ANXA1 SERPINB6 UQCRHL SELENBP1 TMEM260 PDHX TCF4 CDO1 SARS Perturbation; 276 Up Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 4 SARS-CoV is the perturbagen used in this mouse study. EIF4H MAPK3 HSP90AB1 FKBP1A EIF3F COL6A1 EGR1 SPTAN1 PPP2R1A HIST1H1C TSPO UBC NPC2 CXCL10 IFITM3 ANXA3 YWHAB TPM3 ATP6AP2 COL4A1 ANXA2 ACSL5 GNG5 HSPB1 TUBA1A GPX1 OAS1 FCGR2A COL4A2 STAT1 COL4A4 TRIM25 HLA-A B2M MFGE8 CNDP2 REEP5 HSPA8 SLC44A2 PLP2 SAT2 SERPING1 KRT18 KRT7 RPLP2 AQP5 HOPX LMO7 COX6A1 GPRC5A ISG20 LCN2 KRT8 EMP2 CHCHD10 MAL2 TMBIM6 ITGB2 C1QA SNRPB GNB2 TGFBI EMP3 ARHGDIA GRN SYNGR2 PNP PLBD1 IFI44 NDUFS7 ANXA5 CAPNS1 C1QB RRAS LGALS3 SNX3 CDKN2B COX5A PRELID1 CHI3L1 KANK3 COL6A2 KLF2 CDKN1A RPS2 MPEG1 CDH1 ACTB SCNN1A KRT80 MYH14 CLU IRF8 HLA-DRB5 HELZ2 RGL2 RSAD2 IRF7 KIF22 SIRPB1 MS4A7 MS4A6A FCGR1A CORO1A FYB LY86 CLEC7A CTSS GPR171 APOBEC1 FCER1G IFIT3 RTP4 IFIT1B C3 PHF11 XAF1 PSMB8 GBP4 USP18 IFIT2 IFI16 COL3A1 PLAC8 IFIH1 SFTPB GBP2 SAMD9L GBP6 FAP BASP1 RNF213 IFI35 IRGM SAMHD1 GBP7 PSME1 FTH1 PSENEN PSME2 RPL28 GNAI2 RPS28 UQCRB NUFIP1 LASP1 CYR61 SHISA5 CNN2 LY6E IER3 TUBA1B FOS TMA7 ACTG1 AKR1A1 ATP6V0C MAP1LC3B PLTP IRF1 PSMB10 CRYAB MYL12B CHMP4B EIF3G DUSP1 FAM129B TGM2 COX17 RNF187 EEF2 RHOG SIPA1 PLVAP MYL12A ICAM1 RAMP2 SPARC GSTP1 BGN CLIC3 CLDN18 PCBP1 GLTP HIST1H2BI UBL3 ITM2B PSMB9 PXDC1 GBP3 AGER SOX18 CLDN5 FIGF CST3 SNX17 MDH2 HLA-DQB1 CTSH HLA-DQA1 EIF3K NDUFA13 MGP ARPC2 PRX PPP1CA ATP5D SERPINB9 TUBB TMEM176B TAPBP SH3BGRL3 COX4I1 HCFC1R1 VIM CD74 OAZ1 H2AFY RPL18A PLEKHG2 FUCA1 TYROBP IFI30 RP9 RAN CSF1R PRMT2 KRTCAP2 EVA1B CALR NDUFV3 PSAP LIMS2 FXYD5 CFL1 LIMD2 HEXA LAPTM5 CDIPT FAM53B C19ORF59 COX6B1 GPI TUBB2A PDPN IL2RG TMEM259 IGFBP7 CYP2B6 MKNK2 ALOX5AP VWF UBE2V1 GYG1 EDF1 RNASE6 LRG1 TMED10 C1ORF198 GNS ZNF692 HCK LXN HLA-DMA GM2A THEMIS2 PCOLCE CSF2RA PHLDA1 ELOVL1 PRPSAP1 EEF1G SLC25A3 NCF4 FASN EFHD2 SARS Perturbation; 224 Down Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 4 SARS-CoV is the perturbagen used in this mouse study. RPS27A EEF1A1 TBCA SFTPD SUMO2 YWHAQ CSDE1 DPEP1 GOLGA7 PF4 SEPP1 TTN ENPEP ATP1B1 FAU NPM1 PLS3 CAT PPIA PAICS NAP1L1 METTL7A ALDH6A1 NAE1 CAV1 BTF3 RPS17 RPS26 CYP2F1 RPL21 RPL9 RPS12 RPL27 RPS15A RPS24 TPT1 SCGB3A1 RPS8 RPL38 SLC25A4 RPL23 RPL13A RPL24 RPS25 RPS15 DYNLRB2 TJP1 RPS18 RPL19 RPL7A FMO2 RPL11 RPS14 RPS7 RPL7 RPL27A GSN MGST1 CES1 PRDX1 CALCRL HP G0S2 AKAP12 SLC2A4 PKD2 F2R PSMA3 HSD11B1 PON1 FABP4 MB RNASE4 MAMDC2 PCOLCE2 TNNC2 LRAT DBP INMT SCN7A CAV2 ETS1 GPR116 BMPR2 SPTSSA RPL8 TEK PPP1CB FMO1 ATP5J HPGD PTPRB TMEM204 GDPD3 RPS23 MYH1 CHCHD2 SLC34A2 SH3BGRL CTGF DRAM1 COX7A2L RPL3 RPL5 RPS19 UQCRC2 OGN EIF3E SFTPA1 FBXO16 CYB5A SCGB3A2 GNG10 VIMP CRIP1 DCN EFEMP1 EIF3I EEF1B2 RPS4Y1 RPL10A SCGB1A1 LUC7L3 RPL10 LYZ SERPINE2 RPL26 RPS5 C2ORF53 NACA RPS21 DPT PDE5A ALDH1A1 ZNF780A NR1D2 RPL22 RPS10 MYH10 TAGLN RPL4 KLF9 LYVE1 VDAC2 MRPL20 ABRACL GLUL PAIP2 TM9SF2 DDR2 GSTA3 MATR3 JUND CETN2 GIMAP8 ATP5H EID1 BNIP3 HIPK3 RHOQ PABPN1 DDX3X EPC2 TSC22D3 SRP14 SP3 SNRNP48 DYNLT3 SMIM15 RPS9 ITPRIPL2 PCNP SDPR CNBP RPL15 LRRC58 SEPT7 NDUFA1 TCP11 KCNA7 CAPZA2 RPL36AL NDUFA6 RBM3 SERPINB6 UQCRHL SELENBP1 CDO1 TVP23B TRAPPC2 CFDP1 EIF4A2 KIAA1462 VTI1B VPS35 GNG11 RPS3 IVNS1ABP NDUFA4 RBM7 VPS26A TPRG1L ARL1 PHLDB2 MSANTD4 SRSF3 SAT1 NDUFV2 NOP10 POLR2K NRP1 PDCL3 CETN3 PREX2 CD36 TNNI2 ZFP91 WDR45B SUB1 MYLPF VBP1 USMG5 GTF2B EMC2 SARS Perturbation; 291 Up Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 5 SARS-CoV is the perturbagen used in this mouse study. MYH9 EIF4H EEF1A1 MAPK3 HSP90AB1 FKBP1A EIF3F APLNR EGR1 VCP MAP1LC3A PPP2R1A DDX5 HIST1H1C UBC YWHAZ RPL13 IFITM3 YWHAB TPM3 SEPP1 ZCRB1 ANXA2 TUBA1A ANXA11 GPX1 BRD2 ACAA1 COL4A4 TRIM25 B2M MFGE8 REEP5 FAU PABPC1 MSN ANO6 SLC44A2 SPTBN1 ARHGEF12 CNTD1 KDR MCL1 RPS20 DCTN2 BPIFB1 RPL37A RPL9 RPLP2 RPS12 KRT4 RPS11 RPL14 RPL6 HOPX RPS8 PKP4 RPL38 COX6A1 RPSA RPS15 RPS29 RPL7A EMP2 CCND1 RPL27A FTL SMARCD2 TMBIM6 LSP1 STMN1 PGD GSN GRINA EMC10 SNRPB TGFBI ARHGDIA GRN SYNGR2 NDUFS7 MZB1 SNX3 COX5A C16ORF54 KLF2 ZFP36L1 STK4 RPS2 CDH1 ACTB DSP KRT80 CLU IRF8 HNRNPK HLA-DRB5 MAPK11 EDC4 HELZ2 PITPNM1 RGL2 IGJ ARHGDIB CORO1A MYH6 PLAC8 FAP BASP1 TTYH3 FTH1 DPYSL2 EHD4 CLIC4 ETS1 PCBP2 RPL28 GPR116 GNAI2 RPS28 TSPAN13 TOX2 LASP1 CYR61 SHISA5 RPL8 DGKZ CNN2 YBX1 LY6E EPAS1 IER3 TUBA1B FOS ACTG1 AKR1A1 YBX3 SNRK PLTP IRF1 PSMB10 ATP5G3 GRASP CRYAB UNC45B CHMP4B RAC1 EIF3G DUSP1 FMO1 PEBP1 COX17 THRA HPCAL1 EEF2 PLVAP MYL12A TXNIP NFKBIA ID3 RAMP2 SPARC GSTP1 BGN EGFL7 GLTP HIST1H2BI U2AF2 GDPD3 DAZAP2 AGER SOX18 CHCHD2 CA2 RBMS1 COX7A2L RPLP0 VIMP AMMECR1L RPS4Y1 SNX17 BTG1 RPS21 PDE5A GDI2 HLA-DQA1 RPN1 RPL4 ARPC2 PRX EIF5A PPP1CA ATP5D TUBB SH3BGRL3 TMEM160 HNRNPUL1 QDPR JUND GIMAP8 NSMF LTBP3 KDELR1 RPL18 PABPN1 HCFC1R1 VIM ZMYND11 CD74 RPS9 SDPR DDX17 OAZ1 EFNB1 PRPF19 CHST1 NDUFB7 H2AFY RPL18A FAM189A2 SEPW1 EIF4E3 STUB1 ZBTB16 RP9 LAMTOR1 BMS1 PRMT2 GIMAP4 DHX30 NDUFV3 TRMT112 PSAP S100A16 KLHDC3 TEX261 HN1 MRPL28 CFL1 LIMD2 ARF1 LAPTM5 CDIPT SMIM22 RAPGEF3 BLMH RNPS1 PIGQ GPI CCNL1 TMEM259 MKNK2 GYG1 PRPSAP1 EEF1G SLC25A3 KIAA1462 CCNL2 SET DDX39B CDK11A YTHDC1 NUDT16L1 CTDSP2 SMAD4 SUPT5H MARCKSL1 CSNK1A1 CYP2S1 ATP2B1 NUCKS1 RASSF5 FAM160B2 TRUB2 MYO18A METTL14 RFTN1 ANAPC5 DYNC1LI2 HPS4 KIF26B KIF26A MEGF8 GUK1 RAB3GAP1 USHBP1 WASF2 NXF1 GLRX5 UPF3A FSCN1 SARS Perturbation; 209 Down Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 5 SARS-CoV is the perturbagen used in this mouse study. TBCA SFTPD SUMO2 TTN ENPEP ATP1B1 FOXA1 PLS3 CAT PPIA GLO1 UBE2E1 VAMP8 SCP2 METTL7A ALDH6A1 GPR155 PSMA2 RPS17 SERPING1 RPS26 CYP2F1 RPL21 RGS2 IL33 HLF RPS15A CFH WFDC2 RPL23 DYNLRB2 RPS18 FMO2 RPL11 RPS7 MYADM CD81 C5 LPL MGST1 LGALS1 CES1 IL18 GSTO1 HP SCD G0S2 PKD2 CYCS SPARCL1 EGFL6 LAMP1 F2R PSMA3 CTSC HSD11B1 PON1 FABP4 COL3A1 RNASE4 S100G SFTPB MAMDC2 ITGA8 PCOLCE2 TNNC2 LRAT DBP INMT SCN7A THBD UQCRB TEK ELOVL5 ATP6V0E1 RPS23 SLC34A2 SH3BGRL CTGF FABP5 DRAM1 NPNT C16ORF90 VEGFA RPS19 RABL2A UQCRC2 P4HB PDGFRA OGN DMKN SFTPA1 FBXO16 CYB5A WBP5 SFTPC SCGB3A2 GNG10 H2AFZ CST3 COX7A2 CRIP1 DCN EFEMP1 RPL10A SCGB1A1 LYZ SERPINE2 SNRPD2 RPL26 LAMP2 LIMCH1 NACA DPT CTSH ALDH1A1 ZNF780A CHIA NR1D2 RPL22 PPIB MYH10 PRRG3 TAGLN MGP KLF9 LYVE1 NME2 MRPL20 PISD S100A6 NUPR1 ABRACL GSTA3 C6ORF57 ATP5H NDUFB3 SHFM1 BNIP3 PLXDC2 RHOQ ARRDC3 DDX3X PTGR1 TMEM50B SRP14 FHL1 DYNLT3 SMIM15 RPL15 RGCC ERRFI1 NDUFA1 DNAJA1 DSTN RPL36AL NDUFA6 RBM3 FSTL1 VDAC3 ANXA1 SELENBP1 CDO1 TVP23B NDUFA4 NOP10 NRP1 CETN3 CD36 VBP1 USMG5 GTF2B EMC2 NDUFC2 HAUS4 CHCHD1 RGS5 FXYD1 DBI PICALM PPIC SEC61G ACYP2 IGFBP5 RPS27L VCL C8ORF59 SAR1B MRPS18C OAT SSR3 S100A10 RAB9A TRIM46 COL6A3 CD164 RAB5A ACADSB PIN4 PMP22 ACTL7B ATP5J2 GLOD4 BEX4 CD151 ATP5C1 SERINC3 CNTN1 PGRMC1 SARS Perturbation; 348 Up Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 6 SARS-CoV is the perturbagen used in this mouse study. MYH9 MAPK3 HSP90AB1 FKBP1A HSPA5 APLNR EGR1 MAP1LC3A PPP2R1A HIST1H1C TSPO UBC RHOA CXCL10 IFITM3 NGDN ANXA3 UBXN1 ATP6AP2 SEPP1 TMBIM1 ANXA2 FURIN HSPB1 HSP90AA1 TUBA1A GPX1 ACAA1 TCN2 CTSD ACE HLA-A IFITM2 B2M MFGE8 REEP5 FAU YWHAH HSPA8 SLC44A2 PLEC BRI3 CNTD1 KDR AFAP1L1 CAV1 ALB DCTN2 TBCB RPL37A KRT18 KRT7 RPLP2 CEBPD ARL3 RPL14 RPL27 AQP5 HOPX RPS8 COX6A1 RPSA SLPI GPRC5A EMP2 RPL27A FTL TMEM109 TMBIM6 ITGB2 STMN1 PIEZO1 VPS37C PGD GSN GRINA EMC10 SNRPB CYBA TKT EMP3 ARHGDIA GRN RHOB SYNGR2 TWF2 PLBD1 IFI44 NDUFS7 ANXA5 IL18 LGALS3 SNX3 NME1 COX5A DYNLL1 KLF2 CDKN1A RPS2 MANF MPEG1 ABCG1 ACTB SPINT2 KRT80 MYH14 CLU LAMP1 F2R SLC9A3R2 HLA-DRB5 MAPK11 DVL1 CEBPB HELZ2 IRF7 IGJ CORO1A CLEC7A CTSS FCER1G MYL7 IFIT3 RTP4 IFIT1B PHF11 XAF1 PLAC8 IFI35 PSME1 TTYH3 FTH1 ACER2 PSENEN PSME2 GPR116 GNAI2 RPS28 KLF4 UQCRB CYP4B1 TSPAN13 ZFP36 CYR61 SELK SHISA5 CDH5 DGKZ IER2 CNN2 LY6E IER3 TUBA1B FOS TMA7 IGFBP4 ACTG1 ATP6V0C PLTP SMDT1 PSMB10 ATP5G3 CRYAB BAG1 MYL12B EIF3G DUSP1 TMEM100 PEBP1 COX17 RNF187 PLVAP MYL12A TXNIP TXN ICAM1 NFKBIA TPPP3 ID3 RAMP2 SPARC SYF2 ATP6V0E1 GSTP1 CLIC3 EGFL7 CLDN18 PCBP1 GLTP GATA2 HIST1H2BI RIPPLY3 ITM2B JUNB TSPAN7 NDUFA3 TMEM204 SMAGP PSMB9 PXDC1 GDPD3 JUN AGER MED18 CHCHD2 CLDN5 FABP5 VIMP BCAP31 CST3 MAT2A PLIN2 ADAMTS15 SNX17 MDH2 ITM2C HLA-DQB1 HLA-DQA1 RPN1 NDUFA13 LYVE1 ARPC2 PRX NME2 EIF5A PPP1CA ATP5D MRPL20 PFDN6 S100A6 TUBB TMEM176B SH3BGRL3 TMEM160 QDPR JUND LTBP3 COX4I1 RPL18 PABPN1 HCFC1R1 BRK1 VIM CD74 NDFIP1 RPS9 SDPR OAZ1 NDUFA5 EFNB1 PRPF19 CHST1 NDUFB7 ESAM FDX1 RGCC LYPLA2 H2AFY FAM189A2 CDK16 ICAM2 CA4 SEPW1 STUB1 JTB ADRM1 TYROBP NDUFA2 ZBTB16 IFI30 LAMTOR1 RAN BMS1 CSF1R PRMT2 KRTCAP2 ATF4 EVA1B TALDO1 CD97 CRELD2 PIM3 DHX30 HSPH1 ROMO1 CALR NDUFV3 TRMT112 PSAP S100A16 NDUFC1 PQBP1 ATP6V0B FXYD5 AQP1 CFL1 LIMD2 HEXA LAPTM5 CDIPT FAM53B C19ORF59 SMIM22 RNPS1 ADAMTSL2 COX6B1 NDUFA1 CTU2 CCNL1 TUBB2A PDPN IL2RG DNAJA1 TMEM259 MYEOV2 IGFBP7 RTKN2 ALOX5AP DDX39B ATP2B1 GLRX5 FPR2 NDUFB10 AGO4 NDUFA7 TMED2 ECSCR SCAND1 SLC38A2 TMEM256 GPX4 COX14 HIGD2A CD9 S100A13 TMEM147 MIEN1 AGPAT4 MYZAP ZDHHC18 CCDC85B CACYBP PGLS RBM8A DAD1 C1ORF54 MARC2 EIF3C 152 Down Genes from GEN3VA Mouse Lung; Accession: GSE19137 ; Platform: GPL1261 ; Entry 6 SARS-CoV is the perturbagen used in this mouse study. SFTPD IL17A CSDE1 ENPEP ATP1B1 PABPC1 NPM1 PLS3 CAT PPIA PAICS NAP1L1 SCP2 METTL7A RPS17 RPS26 CYP2F1 RPL21 RGS2 RPS12 RPS11 HLF RPS24 SCGB3A1 NFIB WFDC2 ADH1C RPL23 RPL13A RPS15 DYNLRB2 TJP1 RPL7A FMO2 RPL11 RPS14 RPS7 RPL7 C5 NREP MGST1 LGALS1 CES1 PRDX1 HP PKD2 BMP4 HSD11B1 PON1 FABP4 BPIFA1 CA3 COL3A1 RNASE4 MAMDC2 ITGA8 PCOLCE2 TNNC2 LRAT DBP INMT PPP1CB FMO1 BGN PTPRB MYH1 RBMS1 SLC34A2 SH3BGRL DRAM1 COX7A2L RPL3 VEGFA RPL5 RABL2A UQCRC2 OGN EIF3E FBXO16 CYB5A SCGB3A2 SPECC1L DCN GPAM EEF1B2 RPS4Y1 RPL10A SCGB1A1 RPL10 C14ORF166 LYZ RPL26 RPS5 LIMCH1 NACA DPT PDE5A ALDH1A1 ZNF780A CHIA NR1D2 RPL22 MYH10 RPL4 KLF9 NUPR1 CCKAR DDR2 GSTA3 CCNI EID1 BNIP3 HIPK3 DDX3X TP53INP1 PTGR1 MBNL1 FHL1 DYNLT3 SMIM15 PCNP CNBP RPL15 LRRC58 HADH SEPT7 KCNA7 DSTN CAPZA2 MYLK TNS3 MYLIP RBM3 FNDC3B FSTL1 ANXA1 SERPINB6 TMEM260 TCF4 SLC25A3 KIAA1462 VPS26A PHLDB2 MSANTD4 SSR3 RAB9A ATP5C1 BNIP3L FAM102B DEK CBX3 EDAR Coronavirus Perturbation; 357 Up Genes from GEN3VA Human Calu-3 2B4 cells; Accession: GSE45042 ; Platform: GPL6480 ; Entry 1 This study examines cell host-response to infection with novel human coronavirus EMC predict potential antivirals and important differences with SARS-coronavirus. STMN4 SYNGR4 APLNR TGM4 EGR1 UROC1 TLR4 GPT OR1F1 BAG3 IFNL3 TREM2 PTGER1 TMCO2 POM121L4P MASP2 CXCL2 SLC5A12 IFNB1 FERMT3 SPI1 CSF2 UMODL1 KMO CXCL1 SLC22A23 HSPB8 ZEB1 ARID5A PLCB2 HK1 NLRP1 C1ORF162 C1QB CD163 ANKLE1 GLI1 RHEBL1 KLF3-AS1 ADORA2A-AS1 BMP7 B4GALT7 AZIN2 OSM MRO SOST BNC2 FGF8 FRZB ATF3 TMEM88 PRLHR OR2S2 HIST1H4G TRIM49 QPRT KIAA1524 TNFRSF9 TNFSF14 PLD4 SYT6 IL2RB CX3CR1 TNNT2 CKMT2 THRSP HEPACAM2 NEFH COL3A1 MMP12 NRN1 CACNA1G TREM1 TEX19 ARC DRD4 CHST8 GPR116 FOS CRYAB UNC45B DUSP1 JUN FIGF LAPTM5 DNAJB1 ALOX5AP KIF26B CNTN1 RNF113B ACSM2B GJB7 LOC100130964 GEM C17ORF77 TMCO5A C10ORF128 ATOH8 MYO18B ANK1 CYP46A1 PDX1 SSX2 NOVA1 DMD IFNA10 DEC1 ZNF667 ESF1 BPIFA3 ART1 RBM11 ARRDC4 OIT3 FBF1 SLC8A2 DIRC1 IL17F PFN3 FLJ44715 SCML2 KDM6B SLC6A12 RAET1E-AS1 THBS2 PTGER3 CGB1 UTY PDZRN3 ACSBG2 CCDC179 POU2F2 DLK1 ZNF880 SCOC-AS1 LOC101929680 VGLL2 LOC100129648 AQP6 TAF11 RGS22 ZCCHC13 MFHAS1 BIRC8 RSPH10B TBC1D21 CELF4 RFPL1 SPANXA2-OT1 CCL27 MFSD6L CCL23 CREB5 SLC25A2 CECR6 FAM43B RRAD C19ORF26 APOH ADAM32 PIK3R6 NPFFR2 TSPAN18 RFPL2 LOC645752 MESTIT1 MAGEA12 FAM223B KIFC3 CLEC2B DEFA3 COL9A2 NTRK3 CYP1A2 LRRC39 C1ORF194 ZNF132 ZNF479 CAPSL GLI3 LENEP SAMSN1 KCNF1 ZC3H12A UNC5B-AS1 LST1 PI15 SCGB1D2 DDIT3 AKAP17A MAGEB1 LOC100996385 DUSP8 MAB21L2 CLIC2 SLC12A1 ADAMTS17 HTR3D MT3 ASCL2 CSPG4P5 LTA RGMA TAS2R46 SLC25A25 LCA5L STARD9 ZNF597 AMER2 AOC3 FGB C17ORF99 TBX3 SIGLEC7 PI16 EMX2OS TRPC3 GLYCAM1 TPTE2P1 TRAF1 CASP14 OR2C1 FLG MAP4K1 RGS14 SLA FLJ40536 FAM74A1 CCL26 ACTRT3 LOC653581 KIR2DS4 SELM LIN28A ISM1 PNLDC1 GABRA1 HSP90AB6P TGFB1I1 DGKQ SLC5A10 LOC646903 OR13D1 PLCL1 EGR2 COL13A1 CCR8 CHIAP2 PRSS36 RBM24 IL36B MRGPRG-AS1 LOC400756 AHRR MPZ SPG20OS NR4A3 CTAGE10P TMEM75 TBC1D22A-AS1 RGS4 LOC100507316 TNRC6C-AS1 IL16 C2ORF16 SLC22A6 GFAP MGARP PAX7 GNAT1 PAEP MBP EDN2 TPT1P8 FAM187B ASXL3 IFNL1 NOS2 OR7D4 ACKR2 TAGLN3 TCF23 LCE2B BEST1 FAM209B DCD CCDC26 SLC5A5 PIP5K1P1 RAB30 TAGAP C6ORF165 IL27 MAGEB10 SLC22A14 SPOCK3 HSPA6 CCM2L CNKSR2 RFPL3 NSG1 KRTAP5-8 MLN BPI NEXN-AS1 C16ORF86 ALOX12B MLLT4-AS1 ACSM2A LOC100506557 FBXO40 NCKIPSD ART4 TRIM43 NLGN1 AOX1 SUN5 LGI4 FAM167A PPP1R15A LDB3 SLC18A3 ZSCAN1 PLD2 CDK5R2 SLC5A11 FLJ40194 TRIML2 NPAP1 NLGN4X ADAMTS10 PRO2012 SLC38A4 FBXL22 MIR133A1 MRGPRX1 CCR4 KIRREL3-AS3 PRAMEF2 INGX MYCT1 AXDND1 C11ORF44 CPT1C LY6G6E LIX1 SAMD14 BCAR4 SCARA5 ALX4 CSF1 OTOP3 HAO1 PADI4 SPP2 QRICH2 KIAA1551 Coronavirus Perturbation; 143 Down Genes from GEN3VA Human Calu-3 2B4 cells; Accession: GSE45042 ; Platform: GPL6480 ; Entry 1 This study examines cell host-response to infection with novel human coronavirus EMC predict potential antivirals and important differences with SARS-coronavirus. FKBP10 OR8D2 H1FOO CRX DPEP1 CXCL10 OR1N2 TSPYL6 F2 VSTM2B OR8J1 HSD3B2 MAP6 TBC1D10C KCNK13 CCL4 SLC2A9 FOLH1 GLYATL1 POU4F3 GLI2 KCNJ16 GPR65 RAB37 GBP5 CHRM2 CSTA APOC2 CTHRC1 MYH7 SPARC CLDN18 LCE3C SLIT1-AS1 SYT1 SERPINI1 CYP2A7 VN1R1 PCDH8 SRPX LOC283701 GC THNSL2 LOC100130950 SYP HOXC13-AS P2RY12 TRIM22 ADORA1 KCNE4 GPRIN3 ODF3 PRDM9 FUT2 LOC100506242 GUCY2F OR4S1 PCDHGB1 MAGEL2 DAPL1 RORB VAMP1 EPHA8 IL22RA2 DNAH1 CCDC81 SYNGAP1 ARHGEF25 DBIL5P2 CLDN16 FNDC5 OR2A25 LOC541473 OLFM4 KIR3DL3 DNAJB8 ATP4A GP6 CR1 P4HA3 PENK TMEM14B AKR1E2 LHX6 C21ORF49 MXRA5 LYPD6 PTGER2 CLDN6 WSCD1 FLRT1 GJA8 SCN4A F2RL3 LOC100130193 TRHR IL13RA2 ART3 TNFSF4 C21ORF128 FAM154A SIGLEC9 UCMA JAKMIP3 GSTA2 ABCA4 ERMAP LINC00900 S100A12 LRFN2 CCND2 LRRC38 LOC100130920 CCDC155 SULT1E1 GLIS3-AS1 CAMK1 EGFLAM MYPN FSHR HEATR9 LOC100126784 CHRM5 RIMS3 RGAG1 LOC643549 KCNN2 C8ORF46 PRR16 USP27X-AS1 LYPD4 TREX2 SERPINA10 OR2B6 AQP7P1 LOC101060157 HMCN1 LYPD2 LOC149703 RPGRIP1 PCDHA9 CYP7A1 TCERG1 Coronavirus Perturbation; 326 Up Genes from GEN3VA Human Calu-3 2B4 cells; Accession: GSE45042 ; Platform: GPL6480 ; Entry 2 This study examines cell host-response to infection with novel human coronavirus EMC predict potential antivirals and important differences with SARS-coronavirus. STMN4 SYNGR4 IL6 SLC13A1 CCL2 APLNR AADAC IL1A RBP2 TBC1D29 TLR4 CTLA4 GPT GUCA2B TREM2 BTNL8 PTX3 TEX13B TMCO2 POM121L4P OASL CRYBA2 FBN2 CXCL2 VSTM2B MBL2 SPI1 REN SPEM1 DUSP16 ZEB2 ZEB1 C9ORF24 EYA1 PTPRZ1 ARID5A HK1 MRC1 NLRP1 C1ORF162 CD163 GPER1 CXCL8 RHEBL1 B4GALT7 MIOX PAK4 IRX4 SOST BNC2 CXCL13 SFRP1 FRZB PRLHR OR2S2 OR7E91P CD69 QPRT TNFRSF9 PLD4 UPK3A MS4A6A CCL3L3 CYP1A1 MYL1 CKMT2 FSTL4 ASGR1 NEFH COL3A1 MMP12 FGG FAP INHBA CSF3 CRYAB UNC45B DUSP1 NFKBIA FIGF TAF7L IFI44L ARRDC3 IL3RA ALOX5AP GJB7 LOC100130964 GEM ATOH8 ANK1 SSX2 NOVA1 BPIFA3 CGB1 MFHAS1 CELF4 RFPL1 CREB5 C19ORF26 APOH ADAM32 NPFFR2 TSPAN18 RFPL2 KIFC3 CLEC2B COL9A2 ZC3H12A PI15 DDIT3 SLC12A1 ADAMTS17 LTA LCA5L FGB PI16 FLG SLA FAM74A1 KIR2DS4 TGFB1I1 DGKQ OR13D1 LOC100507316 C2ORF16 PAX7 IFNL1 LCE2B BEST1 SLC5A5 RAB30 SLC22A14 HSPA6 RFPL3 NSG1 C16ORF86 ALOX12B ACSM2A FBXO40 LDB3 ZSCAN1 SLC5A11 FLJ40194 TRIML2 FBXL22 KIRREL3-AS3 PRAMEF2 INGX MYCT1 BCAR4 ALX4 OTOP3 HAO1 KIAA1551 P2RY12 LINC00900 EGFLAM KCNV2 LYZL6 HILS1 CETN4P SGIP1 HYPM CES5A B3GNT5 C6ORF58 KGFLP2 SLC35E4 BMP5 GPR111 TET1 ESRRG CYTIP AURKC ZNF772 HCG9 ZNF436 C21ORF91 PGLYRP1 TLR6 C6ORF52 ZSCAN9 LINC01126 GPR182 DCUN1D3 KCNQ1DN LOC100286922 KBTBD8 RGR ZNF432 LONRF3 EFCAB3 SSTR5-AS1 TCEB3C LRRK2 POTEG MRC2 DYNLL1-AS1 VCPKMT RSPH4A ERV9-1 TNFAIP3 IL19 LOC728673 GUCA1A LOC101929412 CITED1 SOCS2 ZNF484 SPDYA HDAC9 TMEM151A ADAMTS3 BRINP2 NATD1 KLHL11 IL23A RXFP4 OR7E5P EDNRA KRTAP3-1 ACTL8 COL21A1 IFNA5 LOXHD1 ASB2 TENM2 DEFB106B DIAPH2-AS1 CELF2 TLR9 ANO3 FLJ25715 HIC1 MSH4 VIP PPAP2B MYT1L GRIK3 SERPINB4 GPR61 LINC01191 ZNF35 IKZF1 LOC650293 C1ORF105 SPOCK1 LINC01096 LCE3D FTCD RUNDC3B KLHL41 NTNG2 GRIK2 CYTH4 ZNF267 DCC TRPC7 S1PR3 CLCA3P KCNK17 KLRC2 GRM7 DRC1 LRRC70 TESPA1 ZNF596 NACAD SPON2 WASH7P ADRA1A SAMD15 MARCH10 SUGCT ZFP37 FLJ13744 COL9A1 CIART COL20A1 CCDC89 NAPSA C10ORF91 FAM129C E2F6 LINC00847 TAC3 TMEM52 ZNF292 ZNF300P1 ZNF841 IQCF6 PLA2G4C TMEM150C CPXM2 LOC283352 IMPG2 TBC1D10A CYP2A13 GJA4 C1ORF204 LOC253805 MPP4 RIBC1 CLSTN3 ADAM6 TG FILIP1L CDH18 ZNF554 AICDA S100A3 HTR2B FAM166B SNCG FLJ33360 ROBO4 OR10H3 SNHG15 RHBG CDKN2AIP ARHGAP25 FAM183B LINC00982 KIAA0408 USH1G NPPB Coronavirus Perturbation; 174 Down Genes from GEN3VA Human Calu-3 2B4 cells; Accession: GSE45042 ; Platform: GPL6480 ; Entry 2 This study examines cell host-response to infection with novel human coronavirus EMC predict potential antivirals and important differences with SARS-coronavirus. ANPEP SMOC1 KCNQ1 TCN2 POFUT1 DMBT1 TP53 ZNF575 TGFB1 BPNT1 METTL7A CXCL17 LINC00342 C6ORF132 WFDC2 H19 HTRA1 SLC25A23 PLEKHS1 ACSS1 IGKV1D-8 HGF ARHGAP23 GSTM2 CDH1 SPINT1 AGRN PPP1R13L PROM2 EPPK1 FZD8 SOX3 RERE RNF44 SETD1B CXCR3 GPR65 INCENP MOGAT1 CDT1 COX6A2 CTGF C11ORF96 PCOLCE FASN KDM6B TRPC3 HSP90AB6P CTAGE10P LOC283701 LYPD6 PTGER2 CCND2 USP27X-AS1 HMGN5 MRI1 LOC285812 FUS EGFEM1P GDPD1 RTN4R HERC3 RADIL GLB1L2 INSR DLGAP1-AS4 LIMD1 PAH TP53I11 VASN SLC38A11 IFITM5 NPDC1 ANO8 HERC2P7 KRT19P2 PPFIA3 TTR RAD51-AS1 CMIP FOXK1 ZFP14 TLCD2 FBXL19-AS1 GNA14 DLX4 SLC2A11 MUC1 L3MBTL1 C9ORF62 PDE4A ZNF205 LOC221272 SLC14A1 PCBD2 PABPC3 MAGEH1 PROC SORBS3 STK24-AS1 QPCTL ANO7 CITED4 UNC5B ZNRF2P1 TMEM178B HOXB8 SEZ6L2 OTP MUC5AC BCORL1 STC1 RHPN1-AS1 CLN8 DMBX1 TNFSF12 NEUROG3 FBXL16 NAT8L RGS9BP ACTG1P4 LOC155060 GPR157 SYCE2 LGI2 C17ORF96 LINC00933 LOC100132363 TP53INP2 DMTN CCL28 MS4A8 GIMAP2 TMEM120B LOC728705 POU3F3 ADRA2A C8ORF60 OR7C2 ESX1 MIR4697HG GPX3 LOC101927221 FAM150A SMG1P5 TMEM213 PLA2R1 CALB2 C1ORF233 SEC31B GGNBP1 MIR210HG PABPC1L2B OR2T5 SNAI3-AS1 PP13439 TNFRSF14 SKI IL10RB-AS1 TEX38 MAPRE3 CYP4F3 LGALS2 TBC1D30 FTHL17 NAT8 LOC253842 SLC25A27 C20ORF96 AQP4 MATN3 LOC100507131 C15ORF38-AP3S2 TOR4A SARS-CoV perturbation; 119 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 1 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. ADAMTS1 CCL2 CYP11B2 EGR1 CXCL10 KLF6 ISG15 CEBPD KLF5 RGS2 RPL38 GADD45A SMAD7 AREG DDIT4 MAFG SPRY2 NRIP1 ZNF574 CXCL8 EGR3 MYC BMP2 KLF10 GADD45B BDNF ATF3 CEBPB E2F8 DUSP2 IFIT1 IFIT2 IFIH1 NFIL3 INHBA EGR4 ZFP36 CYR61 IER2 IER3 FOS DUSP1 NFKBIA JUNB JUN CTGF VEGFA ERRFI1 CCNL1 PHLDA1 MFHAS1 ZC3H12A DDIT3 EGR2 IFNL1 TNFAIP3 LRRC10B BBC3 AMOTL2 BRD1 DUSP6 PPP1R15B GPR144 NEURL3 LIF KLHL15 CCRN4L FLRT3 DUSP5 FOXO6 FEM1B ZIC2 LOC100289333 KIAA0907 IRS2 HMHA1 IER5L EMX2 IER5 NGF TIPARP GRK1 PAPD7 YOD1 ZNF367 IRF2BPL CSRNP1 MIR155HG MIR21 BAMBI SERTAD1 FAM161B ZSWIM6 CLCF1 CHAC1 BHLHE40 TAF1D MAFF NFKBIZ TSC22D2 SERTAD2 ZNFX1 CDC42EP3 SNHG1 PFKFB3 KANSL1 ZNF816 FOXO3 IL11 BTAF1 FOSB SLC25A33 ZBTB34 SH2B3 PPRC1 SOWAHC LHX1 MSL2 ZNF263 SARS-CoV perturbation; 381 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 1 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. HSP90AB1 HYOU1 ETFA PRKACA CSDE1 PPP2R1A MAP7D1 KPNA2 EXOSC8 SWI5 PPT1 YIF1A RBX1 DDX1 NDUFAF2 COL4A1 ACSL5 HSPB1 SRP54 AP2M1 GPX1 BCS1L TMEM39B VARS PLD3 DHRS11 PHB MSN EXOSC5 AKR7A3 PLS3 G3BP2 SLC25A39 ASF1A BRI3 VAMP8 CISD1 PSMA2 CAV1 VKORC1 TSPAN6 DSG2 EPCAM TSTD1 DYNLRB2 HTRA1 ACOT13 CCND1 TMEM109 TAGLN2 BANF1 PRPS1 PDIA6 UQCRC1 SNRPB TGFBI CD81 ARHGDIA RHBDD2 TIMP1 DHCR24 MRPL37 CDCA8 TK1 CAPG FKBP9 UBE2C NUF2 SEC11A HCCS LGALS1 BUB1B DERA FUCA2 DLGAP5 NDUFAF3 GSTO1 LTA4H PDIA5 NME1 HEXB CDCA3 CDC20 DYNLL1 CENPW KIF20A CRIP2 SERPINH1 CKS1B MIOX AP1M2 CD63 PRC1 ERCC6L PBK SPC25 MAD2L1 NDC80 COTL1 BEX1 PSMB8 GINS1 CHRDL1 CDH16 IGFBP6 PSENEN PSME2 SPTSSA PFN1 CRYAB EIF2S3 NDUFA3 SH3BGRL FABP5 H2AFZ COX7A2 CRIP1 LYZ SNRPD2 ACAT2 PPIB NDUFA13 PSMB6 NDUFS3 PRDX5 PSMB5 ISCU TUBB SH3BGRL3 MORF4L1 OAZ1 SEPW1 ROMO1 PSAP TMEM260 HLA-DMA NDUFA4 NOP10 SUB1 USMG5 EMC2 MARCKSL1 GLRX5 PGRMC1 NDUFB10 TMED2 S100A13 DAD1 BNIP3L SERPINI1 OLFM4 TMEM14B S100A3 PTPLB TMEM258 UBE2L3 DPY30 TSPAN31 ANP32A SLC22A11 OST4 PIGF NDUFS2 MECR GNPDA2 SLAIN1 NUP155 ZNHIT3 NR2C2AP ERI3 ATRAID DPM3 UBE2A MAGT1 DEPDC7 UBE2S MRPL34 APOM LIAS SNRPG PRR13 ALAS1 PDLIM1 CYB561D2 MOB1A PDZK1IP1 TM4SF4 SEP15 HAT1 HMGB3 SELT SGCE C11ORF73 ZBTB8OS GGPS1 UBE2M POLR2G SUPT16H ISCA2 MMP10 NQO1 MRPL46 MRPL24 CMSS1 BABAM1 PSMA4 VAMP3 CDC123 CIDEB LAMTOR2 GTF2E1 MCRS1 WBP2 RRM1 EMC4 MND1 ASNSD1 KHDC1 PRKAG1 ACIN1 TMEM33 PSMD1 MPV17 ATP6V1E1 ATP6V1C1 WDR77 SMCO4 GYS1 C14ORF1 TXNDC17 LCMT1 MSRB2 ATP6V0E2 CHMP5 CHCHD4 TMEM243 CIB1 M6PR S100A11 TMEM205 PJA2 RBM42 C19ORF70 TMEM208 OXA1L GPKOW NDUFAB1 C7ORF55 SEC61A1 FAM216A PTRHD1 HSP90B1 UBBP2 MRPL27 CRYZ LYPD1 ARL6IP5 CUTA RBPMS2 MIF SRM MRPS33 AIFM1 EPDR1 C12ORF29 APOO POLD2 DCXR PGAM1 PFDN2 ARMCX6 CFL2 RNASEH2A ACTBP9 GEMIN2 IDH3B PRDX4 CPLX1 TCEAL8 ATP6V1D CKB AP1S1 SARNP HAUS1 NKAP CNOT10 NRBP1 ILF2 SLC29A1 DLG2 PTTG1 TUBA3D HMGB1 WRB MTX2 PSMD13 L3HYPDH ASL TMX1 BRE ATP6V0D1 MRPS9 SLC25A11 SF3A2 TAF12 APOA1BP PARK7 C12ORF57 YPEL5 LSM2 BFAR RABAC1 GALNT7 DDX18 RPA2 UBE2N SMIM20 MRPL13 UBLCP1 TEX30 LAMTOR5 NFU1 PA2G4 SSSCA1 PSMB3 SRP9 PSME3 TIPIN ZNHIT1 WDR12 TFPT CHMP4A C12ORF10 WASH3P GPR160 UBE2E2 STIP1 DYNLT1 COPRS DPP3 TTC1 DAP3 IMMP1L MAGED1 AHCY CCDC124 MAGOH AMZ2 COPS5 PRORSD1P ICT1 MRPL42 TMEM126A PLGRKT NHP2 ORMDL2 MCUR1 PPP1R7 SEH1L PSMD10 MRPL2 STK39 SUCLA2 CCDC58 C19ORF33 GOLT1B EBNA1BP2 ARFIP1 GMPR2 C11ORF48 ZMAT2 VPS72 FLOT2 RAB2B SDC2 DNER CDC26 SAR1A TPRKB LSM7 TMEM14A SARS-CoV perturbation; 91 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 2 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. GDF15 CCL2 EGR1 CXCL10 KLF6 ISG15 KLF5 RPL38 GADD45A SMAD7 MAFG SPRY2 ZNF574 CXCL8 RAB11FIP5 BMP2 KLF10 ATF3 CEBPB PRR12 DUSP2 IFIT1 NFIL3 INHBA ZFP36 IER2 IER3 FOS DUSP1 NFKBIA JUNB JUN ERRFI1 CCNL1 MFHAS1 ZC3H12A DDIT3 TNFAIP3 ZNF267 LRRC10B BBC3 AMOTL2 BRD1 DUSP6 PPP1R15B GPR144 LIF KLHL15 FLRT3 DUSP5 FOXO6 ZIC2 KIAA0907 IER5 TIPARP ZNF367 IRF2BPL CSRNP1 MIR21 BAMBI FAM161B ZSWIM6 CLCF1 BHLHE40 TAF1D MAFF NFKBIZ TSC22D2 SERTAD2 ZNFX1 SNHG1 PFKFB3 KANSL1 IL11 SLC25A33 ZBTB34 SH2B3 PPRC1 MSL2 ZNF263 LINC00152 SPRED3 C1ORF74 VMP1 PAN3 PPP1R18 RNF151 NPTN-IT1 SPIN2A BCOR ZNF513 SARS-CoV perturbation; 409 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 2 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. FAM8A1 HSP90AB1 SUMO3 CTSL GHITM YWHAQ ETFA CSDE1 PPP2R1A KPNA2 EXOSC8 ATP6V1A PPT1 ANXA3 YIF1A ATP6AP2 MIPEP RBX1 DDX1 NDUFAF2 ACSL5 LAP3 HSPB1 GRPEL1 SRP54 HSP90AA1 GPX1 BCS1L TMEM39B PSMC6 TP53 TST REEP5 POR PHB MSN EXOSC5 PLS3 NTS UBQLN2 PAICS PIGU RAB5C RBKS ASF1A LYPLA1 MRPL9 VAMP8 UFC1 ATP6V1B2 PSMA2 ENO1 OCIAD2 VKORC1 TSPAN6 EPCAM HTRA1 CCND1 TMEM109 TAGLN2 TMBIM6 BANF1 PRPS1 PDIA6 UQCRC1 TGFBI CD81 ARHGDIA RHBDD2 TIMP1 NDUFB5 DHCR24 MRPL37 CDCA8 CAPG UBE2C NUF2 COQ5 SEC11A ANXA2P2 LGALS1 KNSTRN AURKA DLGAP5 GSTO1 CDCA2 PDIA5 NME1 TPX2 HEXB ANLN CDCA3 CDC20 DYNLL1 CENPW TPI1 KIF20A CRIP2 IGFBP3 SERPINH1 CKS1B MMP1 AP1M2 NUCB2 DCK CD63 UPP1 PRC1 MCM5 BORA SPC25 MAD2L1 NDC80 COTL1 BEX1 PSMB8 GINS1 CHRDL1 IGFBP6 PPA1 PDE2A PSENEN PSME2 SPTSSA PFN1 CRYAB PEBP1 MYL12A CHCHD2 SH3BGRL FABP5 H2AFZ COX7A2 CRIP1 LYZ SNRPD2 ACAT2 NDUFA13 TAGLN PSMB6 NDUFS3 PRDX5 PSMB5 RAP1B ISCU TUBB SH3BGRL3 CETN2 EID1 NDUFB3 OAZ1 SEPW1 ROMO1 PSAP ATP6V0B AQP1 TUBB2A DNAJA1 PSMA6 VDAC3 NDUFA4 SAT1 NOP10 SUB1 USMG5 EMC2 MARCKSL1 RPS27L OAT CD164 PGRMC1 NDUFB10 TMED2 DAD1 BNIP3L TMEM14B S100A3 PTPLB TMEM258 UBE2L3 DPY30 ANP32A PIGF NDUFS2 MECR GNPDA2 DPM3 UBE2A MAGT1 DEPDC7 UBE2S MRPL34 APOM LIAS SNRPG PRR13 ALAS1 MOB1A PDZK1IP1 SEP15 HAT1 HMGB3 SELT SGCE C11ORF73 ZBTB8OS GGPS1 POLR2G ISCA2 MMP10 NQO1 MRPL46 CMSS1 BABAM1 PSMA4 CDC123 LAMTOR2 GTF2E1 WBP2 RRM1 EMC4 PRKAG1 TMEM33 PSMD1 MPV17 ATP6V1E1 ATP6V1C1 GYS1 C14ORF1 TXNDC17 LCMT1 CHMP5 TMEM243 CIB1 M6PR S100A11 TMEM205 RBM42 C19ORF70 TMEM208 GPKOW NDUFAB1 C7ORF55 FAM216A PTRHD1 HSP90B1 MRPL27 CRYZ LYPD1 ARL6IP5 MIF SRM MRPS33 AIFM1 C12ORF29 APOO POLD2 DCXR PGAM1 ARMCX6 CFL2 ACTBP9 GEMIN2 IDH3B PRDX4 ATP6V1D AP1S1 SARNP HAUS1 NKAP CNOT10 NRBP1 SLC29A1 DLG2 PTTG1 TUBA3D HMGB1 L3HYPDH ATP6V0D1 MRPS9 SLC25A11 SF3A2 TAF12 APOA1BP PARK7 RABAC1 GALNT7 DDX18 RPA2 UBE2N SMIM20 MRPL13 UBLCP1 TEX30 NFU1 PA2G4 SSSCA1 PSMB3 SRP9 PSME3 TIPIN ZNHIT1 WDR12 TFPT CHMP4A UBE2E2 STIP1 DYNLT1 COPRS DPP3 TTC1 DAP3 IMMP1L MAGED1 AHCY CCDC124 MAGOH AMZ2 COPS5 ICT1 MRPL42 TMEM126A PLGRKT ORMDL2 MCUR1 PPP1R7 PSMD10 MRPL2 SUCLA2 GOLT1B EBNA1BP2 C11ORF48 ZMAT2 SDC2 DNER CDC26 SAR1A TPRKB LSM7 TMEM14A TMEM230 SDHAF2 GSS POLR3C ATIC NPM3 C19ORF10 NOP58 TTYH1 PI3 SLC25A15 UCHL3 MRPS35 BOLA3 MBD4 MANBAL ACTL6A UQCRQ GSKIP TSPAN4 PIH1D1 ANP32E PHLDA3 TOMM34 PCNA ALKBH3 POLE3 PTPLAD1 EMG1 ZCCHC9 DCTN3 THYN1 CORO1C PSMC1 UGT8 C2ORF74 PRIMPOL FAM127A BCAS2 ANXA2P1 HAVCR1 NIF3L1 HAUS7 YIPF3 NOSIP RCN2 TIMP2 LMAN1 HRSP12 UBE4A RABL3 ANXA2P3 GNG12 MRPS23 HDAC1 POLR2E CKLF SMIM6 TRAPPC3 MSH2 SMARCA5 WDR54 CTSO UCHL5 ZW10 NDUFA8 TBC1D19 TAF13 VRK1 SARS-CoV perturbation; 7 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 3 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. CCL2 EGR1 CXCL10 NFKBIA IFNL1 TNFAIP3 NEURL3 SARS-CoV perturbation; 493 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 3 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. SRP19 SUMO1 UBL5 FAM8A1 HSP90AB1 UBE2D2 PSMD8 SUMO2 CTSL GHITM YWHAQ CSDE1 PPP2R1A KPNA2 UBE2K PPT1 RALA YWHAB RBX1 DDX1 GNG5 LAP3 HSPB1 SRP54 AP2M1 TUBA1A GPX1 BZW2 UBQLN1 PSMC6 PRIM1 TDP2 NPM1 PRKAR2B PLS3 FKBP1B UBQLN2 PLP2 TOP2B G3BP2 OXSM SLC25A39 TMBIM4 GLO1 C1D ASF1A SLC9A6 CISD1 DHRS1 NAE1 CAV1 RNF128 OCIAD2 PFDN5 RPS17 KRT18 TSPAN6 RPS8 RPL30 EPCAM RPL24 RPS25 FNBP1L RPS13 CEP170 CHCHD10 CCND1 FTL BANF1 PRPS1 UQCRC1 SNRPB CD81 SRSF9 CCNA2 EZH2 CAPG TUBG1 UBE2C NUF2 SEC11A ANXA2P2 RBBP8 LGALS1 ANXA5 VDAC1 MRPL15 DERA METTL9 DLGAP5 CAPNS1 PRDX1 HSD17B10 GAPDH LTA4H HEBP1 PDIA5 NME1 CBR1 CDC20 DYNLL1 OSTC CENPW TTK LDHA PTGFRN KIF20A CRIP2 TRAM1 CKS1B SPINT2 DCK CD63 PRC1 UBE2Q2 MRPS36 DBF4 SPC25 MAD2L1 NDC80 BEX1 POLE2 GINS1 CHRDL1 CLDN2 PPA1 AIDA PSME1 DPYSL2 PSENEN PSME2 PFN1 YBX1 CRYAB TXN ITM2B SH3BGRL FABP5 RBBP7 EIF3E WBP5 H2AFZ VIMP BCAP31 MAT2A COX7A2 CRIP1 EIF3I C14ORF166 LYZ SNRPD2 RPS5 PPIB PSMB6 RAP1B ISCU C1QBP LAPTM4A SH3BGRL3 MORF4L1 EID1 BNIP3 PLXDC2 DYNLT3 OAZ1 PSMB4 JTB SOD1 RAN CCT3 TALDO1 HSPH1 ROMO1 AQP1 CFL1 COX6B1 NDUFA1 PSMA6 RPL36AL VDAC3 EDF1 GNG11 NDUFV2 NOP10 USMG5 EMC2 DBI SEC61G PGRMC1 TMED2 GPX4 S100A13 DAD1 BNIP3L SERPINI1 TMEM258 DPY30 ANP32A OST4 PIGF NDUFS2 MECR GNPDA2 SLAIN1 ZNHIT3 ATRAID MAGT1 DEPDC7 UBE2S MRPL34 SNRPG ALAS1 SEP15 HAT1 C11ORF73 ZBTB8OS POLR2G SUPT16H ISCA2 MMP10 MRPL46 BABAM1 PSMA4 VAMP3 CDC123 RRM1 MND1 ASNSD1 PSMD1 CHMP5 TMEM243 CIB1 M6PR S100A11 PJA2 NDUFAB1 FAM216A UBBP2 CRYZ ARL6IP5 MIF AIFM1 EPDR1 C12ORF29 PGAM1 ARMCX6 PRDX4 TCEAL8 SARNP HAUS1 CNOT10 PTTG1 HMGB1 MTX2 TMX1 ATP6V0D1 TAF12 APOA1BP PARK7 RABAC1 GALNT7 SMIM20 MRPL13 UBLCP1 NFU1 PA2G4 SSSCA1 PSMB3 SRP9 TIPIN WDR12 DYNLT1 DAP3 IMMP1L MAGED1 AHCY MAGOH COPS5 PRORSD1P MRPL42 PLGRKT NHP2 ORMDL2 MCUR1 MRPL2 STK39 SUCLA2 GOLT1B EBNA1BP2 ARFIP1 C11ORF48 ZMAT2 SDC2 CDC26 LSM7 TMEM14A NOP58 SLC25A15 UCHL3 MRPS35 BOLA3 MANBAL ACTL6A UQCRQ GSKIP ANP32E PTPLAD1 EMG1 CORO1C BCAS2 TIMP2 SMIM6 MSH2 SMARCA5 NDUFA8 SYNCRIP NDUFA12 HSD17B2 SPIN1 PTMA LYSMD2 COMMD8 SLC25A5 DKC1 ZDHHC6 WDR83OS ATG5 SGMS1 C15ORF40 PAM DONSON PCBD1 SUSD5 TMEM185B POLR2J NOC3L SLC44A3 NUP37 PIGP MRPL16 SSR4 GNAI1 GJA1 AHSA1 FAM96A CDC7 MFSD5 CYP20A1 ZNF593 ATP5L SNX7 PTDSS1 KDELC1 EIF2A SYPL1 PCMT1 MGLL SSB NAA35 SERINC1 CAP1 BUB3 HTATSF1 AMD1 ACTR10 TNFRSF21 APEX1 DIABLO RFC4 PSMA1 NELFE FAM107B MOB4 SKP1 MCEE TRMT11 STEAP1 RPS6KA3 NIT2 PRPF3 MTERF3 HSF2 LINC00621 MICU2 PDCD10 MMS19 ETHE1 BZW1 PSMD14 LACTB2 TMEM251 SEPT10 SLC10A3 VAMP7 SLC39A10 ARMCX2 RPAP3 SPCS1 POP5 SNX4 NOL11 HMGN4 TMPO MRPL32 NAA50 ELOVL7 PSMA7 CMC1 UQCRH HOXB7 SSR2 PUS7 CXXC5 MRPL17 CCT7 AP3S1 CDC16 DHX40 ANKRD39 HMGN3 PPP3CA RUVBL1 UXT PNPT1 ABCB10 FAM60A ADSL MAP4K3 HMGB3P1 USP1 GTF3C6 MRPS30 LDOC1 PVRL3 FGF13 GMNN ST13 RPP40 KCTD9 NUP107 UBE2G1 HDHD2 KPNA3 PAPOLA DCTN6 LAMB1 MMGT1 EPRS C15ORF61 TUBB6 MMADHC DYNLL2 SNHG6 SNRPA AKR1B1 SEC11C SEC24B NAA10 ITGB3BP GLRX2 ERH NUP93 CERS2 SCG5 C18ORF32 TMEM50A PITPNB MRPL1 ETF1 TUFM IPO5 UBA3 PFN2 RPN2 CBX1 HEBP2 NAA20 SNX10 MPLKIP PPP1CC LEO1 STAG2 PFKM USO1 BEX2 GNL2 PRKRIR TMSB10 CCDC53 HSPE1 EBPL TMEM203 NDUFA9 SARS-CoV perturbation; 23 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 4 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. CCL2 CYP11B2 EGR1 CXCL10 RGS2 NR4A2 FOS DUSP1 NFKBIA PIM3 HSPH1 DNAJB1 ZC3H12A IFNL1 TNFAIP3 NEURL3 NFKBIZ SSC4D HSPA1A TCF15 HMX1 IL17C DHRS2 SARS-CoV perturbation; 477 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 4 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. SRP19 F2RL1 SUMO1 UBL5 FAM8A1 UBE2D2 PSMD8 SUMO2 GHITM YWHAQ PPP2R1A KPNA2 EXOSC8 NPC2 UBE2K PPT1 YIF1A YWHAB DDX1 GNG5 LAP3 STOML2 SRP54 AP2M1 TUBA1A GPX1 FBL AGPS PSMC6 PRIM1 TDP2 PHB NEDD8 NPM1 PRKAR2B PLS3 FKBP1B UBQLN2 PLP2 TOP2B G3BP2 OXSM SLC25A39 TMBIM4 GLO1 C1D RDH14 ASF1A SLC9A6 LYPLA1 VAMP8 SCP2 CISD1 NAE1 PSMA2 RNF128 OCIAD2 PFDN5 RPS17 KRT18 RPL6 TSPAN6 RPS8 MZT2A RPL30 EPCAM RPL24 RPS25 CKS2 FNBP1L RPS13 RPS18 RPS29 CEP170 CHCHD10 CCND1 FTL BANF1 PRPS1 UQCRC1 SNRPB CD81 UNC50 TIMP1 CCNA2 EZH2 CAPG TUBG1 CDKN3 NUF2 SEC11A ANXA2P2 SPAG5 LGALS1 MRPL15 DERA METTL9 DLGAP5 CAPNS1 HSD17B10 GAPDH HEBP1 PDIA5 NME1 RMI1 CBR1 CDC20 DYNLL1 OSTC CENPW TTK LDHA PTGFRN KIF20A CRIP2 CKS1B SPINT2 FIBP DCK CD63 UBE2Q2 MRPS36 SPC25 MAD2L1 NCAPG2 NDC80 BEX1 POLE2 PSMB8 GINS1 CHRDL1 VCAN CLDN2 PPA1 AIDA PSME1 DPYSL2 PSENEN PSME2 PFN1 YBX1 RAC1 TXN ITM2B SH3BGRL FABP5 RBBP7 WBP5 H2AFZ VIMP BCAP31 COX7A2 CRIP1 EIF3I C14ORF166 LYZ SNRPD2 RPS5 PPIB MYH10 PSMB6 PRDX5 RAP1B ISCU C1QBP LAPTM4A TUBB MORF4L1 EID1 BNIP3 PLXDC2 DYNLT3 JTB TALDO1 ROMO1 AQP1 CFL1 COX6B1 NDUFA1 GPI RPL36AL VDAC3 EDF1 GNG11 NDUFV2 NOP10 CETN3 USMG5 EMC2 DBI SEC61G PGRMC1 TMED2 GPX4 S100A13 DAD1 BNIP3L SERPINI1 TMEM258 DPY30 ANP32A OST4 NDUFS2 GNPDA2 SLAIN1 ATRAID DEPDC7 LIAS SNRPG TM4SF4 SEP15 HAT1 C11ORF73 ZBTB8OS POLR2G SUPT16H ISCA2 MMP10 MRPL46 BABAM1 PSMA4 VAMP3 GTF2E1 RRM1 EMC4 ASNSD1 CHMP5 TMEM243 CIB1 S100A11 PJA2 C19ORF70 NDUFAB1 FAM216A MRPL27 CRYZ ARL6IP5 MIF AIFM1 EPDR1 C12ORF29 APOO PGAM1 ARMCX6 RNASEH2A IDH3B PRDX4 TCEAL8 SARNP HAUS1 CNOT10 PTTG1 HMGB1 TMX1 TAF12 APOA1BP PARK7 RABAC1 GALNT7 SMIM20 MRPL13 UBLCP1 LAMTOR5 NFU1 SSSCA1 PSMB3 SRP9 TIPIN GPR160 DYNLT1 DPP3 DAP3 IMMP1L MAGED1 AHCY MAGOH AMZ2 COPS5 PRORSD1P MRPL42 NHP2 ORMDL2 MCUR1 MRPL2 STK39 SUCLA2 CCDC58 GOLT1B EBNA1BP2 C11ORF48 ZMAT2 SDC2 CDC26 LSM7 TMEM14A SLC25A15 UCHL3 MRPS35 BOLA3 ACTL6A UQCRQ GSKIP ANP32E PCNA PTPLAD1 EMG1 CORO1C UGT8 FAM127A BCAS2 NIF3L1 TIMP2 CKLF MSH2 SMARCA5 NDUFA8 TAF13 SYNCRIP NDUFA12 PTMA LYSMD2 COMMD8 SLC25A5 DKC1 ZDHHC6 WDR83OS SGMS1 C15ORF40 DONSON SUSD5 POLR2J NOC3L NUP37 PIGP MRPL16 SSR4 GNAI1 GJA1 FAM96A MFSD5 ZNF593 ATP5L SNX7 PTDSS1 SYPL1 PCMT1 SSB BUB3 HTATSF1 ACTR10 TNFRSF21 APEX1 RFC4 PSMA1 NELFE FAM107B MOB4 MCEE STEAP1 NIT2 PRPF3 MTERF3 LINC00621 MICU2 PDCD10 ETHE1 PSMD14 LACTB2 TMEM251 SEPT10 VAMP7 SLC39A10 ARMCX2 RPAP3 SPCS1 POP5 SNX4 HMGN4 MRPL32 ELOVL7 PSMA7 CMC1 UQCRH PUS7 CXXC5 MRPL17 AP3S1 CDC16 ANKRD39 HMGN3 RUVBL1 UXT PNPT1 ABCB10 ADSL HMGB3P1 USP1 GTF3C6 MRPS30 LDOC1 PVRL3 FGF13 GMNN KCTD9 NUP107 HDHD2 LAMB1 MMGT1 C15ORF61 TUBB6 MMADHC SNHG6 SNRPA AKR1B1 SEC11C SEC24B NAA10 ITGB3BP GLRX2 ERH SCG5 C18ORF32 TMEM50A MRPL1 UBA3 PFN2 CBX1 HEBP2 NAA20 SNX10 MPLKIP LEO1 PFKM BEX2 GNL2 TMSB10 CCDC53 EBPL SNRPE FAM122B YAE1D1 STAU1 EIF2D RPL32 SUMO4 EXTL2 RPL29 BBS5 CUEDC2 PDHB NARS LCLAT1 AMIGO2 RAB1B FGFBP3 DECR1 MAD2L2 EPHA7 CHTF8 EMC9 SF3B5 SEC23A ETFB MRPL11 GEMIN6 C1ORF122 TOMM5 TAX1BP3 LRP11 RPL34 GEMIN5 TSEN34 LDHB C9ORF41 RNF20 IER3IP1 CDK4 SARS-CoV perturbation; 338 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 5 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. GLA UBB ERMP1 UHRF1 SYVN1 HSP90AB1 HSPA5 SH3BGR CSDE1 UBC ATP6V1A PDZD11 PPT1 HSPB1 BAG3 ADA HSP90AA1 HMOX1 BRD2 SNIP1 PTX3 TUBA4A RBM28 HLA-A REEP5 HERPUD1 EXOSC5 NUP98 HSPA8 ANO6 SLC44A2 PIGU G3BP2 NFS1 ASCC1 TMEM30A GBE1 CD55 NXT2 ZFAND1 MNAT1 DEDD2 FRK RGS2 CCDC7 UPK1B DEPTOR FOPNL EPCAM CYBRD1 ACOT13 SYBU PRPS1 DNAJB2 MAP3K11 RHBDD2 NCSTN TOP2A PNP LMNB1 CDKN3 UBE2C AREG CREG1 NEK2 KIF18B TMEM38A DLGAP5 CDC6 ORC1 PRDX1 PPARG IL18 TPX2 ANLN CDC20 ALDH9A1 CENPW TTK KIF20A SPTLC2 TOPORS CST7 TGFBR3 CAMP BMP2 SLC2A3 SERPINH1 CKS1B MMP1 MANF ABCD3 BMP4 JMJD6 ZNF217 KITLG CLU NR2F2 CTR9 CD63 ECT2 NUSAP1 SPC25 TINAGL1 SLC7A11 PIM1 FAP GPR116 SPTSSA PTGES3 FOS CRYAB DUSP1 ADIPOR1 COX17 TXNIP TSPAN7 GDPD3 FABP5 BCAP31 LAMP2 ALDH1A1 NR1D2 GLUL NDUFB11 HIPK3 ARRDC3 RGCC RAN HSPH1 CALR ATP6V0B DNAJA1 DNAJB1 MYLIP PDHX GYG1 HLA-DMA TVP23B ARL1 SAT1 CTDSP2 BNIP3L ARRDC4 ZC3H12A PPP1R15A TRHR DRC1 CDKN2AIP CCRN4L ZIC2 IER5 CSRNP1 NFKBIZ DEPDC7 UBE2S ALAS1 WBP2 GYS1 CHMP5 CIB1 PJA2 HSP90B1 UBBP2 C12ORF29 PGAM1 ARMCX6 PTTG1 UBE2E2 STIP1 SUCLA2 ARFIP1 UCHL3 UQCRQ GSKIP TOMM34 POLE3 UGT8 RCN2 LMAN1 AHSA1 MGLL SERINC1 SLC39A10 CCT7 ANKRD39 MRPS30 KCTD9 LAMB1 C15ORF61 AKR1B1 STAG2 HSPE1 HSPA1A KIAA0430 HSPA2 C3ORF38 CWC22 NEK7 SPSB3 ERVMER34-1 RB1CC1 FOLR1 AGPAT5 DDB2 MXI1 SDF2L1 MRPL18 ARG2 CHST6 SIRT1 PCSK5 SUCLG2 CPN1 TMEFF1 PPAP2A ARHGEF18 RLF PRPF8 MORC4 SNHG8 NKRF GNA13 RRN3 FOXF2 TMEM245 CCDC117 ERO1LB PLCD4 IRX5 AGPAT9 CCDC109B C19ORF52 TCP1 MXD1 ZP1 RPS6KC1 SLC25A46 ZFAND2A GPR89A ZNF317 DNAJB4 ATP2C1 SOAT1 USPL1 TOB2 AFTPH WBP11 FAM117A LOC101926915 INTS6 BTD CDC25B HSPA4L ZBTB8A SOSTDC1 ODC1 TMEM55A GRHL3 NUDT9 TTC7B YDJC EIF2B5 ZNF491 GPBP1 MALT1 HSD17B11 DNAJA4 HIST1H2BE SLCO2A1 VAV3 HIST1H3G USP10 PLEKHG6 TXNDC12 PTBP3 TACR2 RUVBL2 PLEKHH2 DNAJB9 SERINC5 SGMS2 ADORA2B MUM1L1 FAM13A NCOA4 LGALS14 TAF4B ZMAT3 RSRP1 KHDRBS3 CSTF1 MFAP1 LOC285627 ACBD5 WDR11 NUDC RSPO3 LIPF RHPN2 TMEM257 AASDH E2F7 XPR1 RXFP1 SPINK6 ADCY8 FKBP4 SYT13 TOB1 GRB7 CUL4B GPR64 CADPS2 GOT2 HSPD1 FXR2 DUSP10 TNFRSF19 GFM2 PIP5K1B PDE4B MKRN1 PAPD5 FLJ45513 DLAT SKA2 VGF TMEM47 MLH1 SF3A3 RANGAP1 MRPS6 SLC38A6 GLB1 ARL6IP1 ITIH2 CKAP5 SARS-CoV perturbation; 162 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 5 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. ADAMTS1 CCL2 EGR1 SPACA3 PMEPA1 PITRM1 HOXD12 INHBE KRT20 TNFSF10 EXT1 MALAT1 PTGER4 TGFBI TP53I3 HJURP ICAM5 CXCL8 MSC CLDND2 GPR87 COL17A1 FGF16 NLK HNRNPH1 ATOH1 GCNT1P1 RGP1 PICK1 LFNG INHBA SLC25A22 IGDCC4 LRRC17 SGK1 CTGF ACAT2 TAGLN EPC2 MARCKSL1 ACYP2 GABRA1 HMCN1 FILIP1L NPPB C9ORF62 LIF FLRT3 NGF MIR21 CHAC1 BTAF1 PDZK1IP1 C12ORF57 TAF13 THOC1 HHCM LTC4S LINC00529 TLDC2 RPL23AP53 SCARNA2 ZNF512 KIAA1683 EXTL1 PARD6A FBLL1 PAN2 TMEM194A RAPGEFL1 ETNK2 YTHDF3-AS1 KLF7 TRIM72 POLR1C CNN1 ZNF322 LINC01220 OGT APOBEC3C GP1BB HAMP LOC728061 ARGLU1 P2RX3 KRCC1 YTHDF1 LOC100506022 SYT4 HTR1D SRSF2 LOC102606465 GNAZ TNP1 MSANTD2 LOC100289361 TTC32 IZUMO2 DUSP21 NUFIP2 LMNTD2 LRRC3 CLEC2L DQX1 ANKRD1 SRPK3 PPM1H C1ORF226 ZDHHC23 SORCS3 LOC100286895 CNFN KCND1 NEAT1 MGEA5 SLC7A3 LENG8 ANKRD45 METTL25 HIST1H4C NOP14 C6ORF25 C15ORF52 ID1 EFNA1 HIST2H2AA3 PPP1R2P9 MIR663AHG SRSF7 TAPT1-AS1 ANAPC7 HIST1H1A ADRA2C SNORD104 ACRC SLC25A25-AS1 LOC101929064 ZNF32 ENC1 AOC2 TMEM179 ZNRF3 SSC5D MN1 CLHC1 GPR75 LINC00973 COL7A1 LOC101929153 BAI2 KRT32 TMEM170B COMP SAMD4A XKR4 C10ORF71 LINC01121 VPS51 WFDC3 BLID HNRNPA0 LOC100133985 SARS-CoV perturbation; 231 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 6 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. F2RL1 EGR1 LARP1 EP300 WFDC10A ZNF274 HMOX1 PTX3 ENPP7 TM4SF5 FKBP1B HKDC1 OXSM TLCD1 DDAH2 DEDD2 HOXC6 CXCL6 KRT18 PNRC1 LCN2 SMARCD2 VASP RPS6KA1 SEC24C WDR13 STAC3 CORO2B ATP6V1F SCD GNPDA1 CXCL8 PLEKHA1 EGR3 FOXO1 GPR87 CNKSR1 GTF2IRD1 ZNF217 FRAT1 MC1R SOX12 TPBG FOSL2 HIST1H2AJ CCL20 CD3D VCAN NFIL3 FAP LIPG ARNTL LRRC17 ZFP36 IER3 FOS DUSP1 HMGCS1 TXNIP NFKBIA ACAT2 JUND PLXDC2 RHOQ DDX17 NAB1 SET CYP2S1 USHBP1 SCAND1 BNIP3L MFHAS1 ZC3H12A GABRA1 TGFB1I1 GJA8 ERMAP TNFAIP3 IL19 SOCS2 SPON2 PROC FLRT3 DUSP5 IRS2 TIPARP IRF2BPL BAMBI ZSWIM6 BHLHE40 NFKBIZ ZNFX1 SH2B3 LHX1 ZNF263 C1ORF74 PAN3 MFSD5 MGLL TMEM251 ANKRD39 GTF3C6 DYNLL2 SNRPA CCDC53 EXTL2 FAM117A HIST1H2BE TOB1 ID1 EFNA1 SNORD104 TSPYL4 EPB41L4A-AS1 TNFSF15 CREB3L4 FOXO4 ZCCHC24 MAP1B CORT MNS1 ZNF618 TBL1XR1 SRXN1 SURF2 PIK3C2B C15ORF65 AKR1B10 SRI TRAPPC12 VEGFB C7ORF60 ARFIP2 C6ORF120 EVPLL TAF7 HYAL1 INSIG1 PURB SPATC1L GSPT2 SETD2 MBD5 SNX9 NOA1 HSD17B7 PCDHA10 PRR15 KRBA2 GOLT1A FRMPD1 TPST2 IK PLCH2 TACR3 RRAGC C19ORF54 EID2B CCDC64B MARK4 NCBP2-AS2 PGM1 RNF19A KDM3B MYH7B LINC01348 RIPK3 HCG11 HOXA5 LOC100129361 MEA1 HDGF MRGBP GAS2L1 HACL1 B3GALT4 ARRDC2 SCARNA17 DLG4 ORAI1 PIR CREBRF TTLL13 RRAGB TP53TG5 MCU LOC100128843 C19ORF40 MSMO1 TMEM139 LINC00543 FAM46B ITPKC CPNE1 HRCT1 HMGCR RNF25 BLCAP MAML1 UFSP1 NDRG4 SQLE ID2 ZNF212 KLF3 TBC1D28 LHB TTC21B IP6K3 GZMM KLHL24 NARF LOC728819 SALL1 MAP2 TIFAB TRIM41 TTF1 PRRX2 SCAF8 CTBP2 FAM129A SMIM1 HIVEP2 C17ORF50 DOK4 MTFR1L BLOC1S4 YTHDF2 CLIP2 ATXN1L SARS-CoV perturbation; 269 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 6 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. HDAC2 CCL2 HYOU1 TGM4 CTSL KPNA2 ACADM RRP9 PPP1R14D TIMM9 ANXA3 YIF1A SERPINE1 TMEM39B PLOD2 TSPAN8 EPB41L3 TIMM10 KRT20 NUP85 UAP1 REEP6 CRADD OCIAD2 MT2A EXT1 SH3BGRL2 EPCAM RND3 STATH ACOT13 AADAT TMEM109 PRPS1 TGFBI TOP2A ZWINT CDCA8 CCNA2 SDC4 TK1 TROAP KIF18B BUB1B KIF2C KIF14 RRM2 CDK1 CDC6 MPND CDCA2 GLDC NETO2 ANLN NCAPH CDCA3 NTSR1 DTL PDGFD CRIP2 CHTF18 BDNF PLAUR SRSF1 KLK5 SHISA2 DSPP UPP1 COLEC12 FBXO5 MTFR2 SPDL1 FANCI ASF1B CKAP2L FAM64A FAM83D SGOL2 NUSAP1 MCM5 PBK BORA SPC25 MELK DEPDC1 MAD2L1 CCNF GPR15 GLIPR1 NDC80 CENPE NEIL3 MYOM2 POLE2 PSMB8 GINS1 KIF18A LRRC3B CHRDL1 UNG GBP2 MITD1 UBE2L6 FST TSPAN13 TMA7 CRYAB EIF2S3 ST5 PSMB9 COX7A2 CRIP1 NR1D2 NDUFA13 TAGLN PRDX5 CRELD2 ATP6V0B LBH USMG5 PPIC DAD1 DEK RBM24 DCD OLFM4 PRR16 KBTBD8 TENM2 LOC285812 FUS NGF SLAIN1 NUP155 DEPDC7 UBE2S TM4SF4 HAT1 RRM1 FAM216A C12ORF29 L3HYPDH SF3A2 TEX30 DNER PCNA CORO1C YIPF3 ZW10 TBC1D19 VRK1 SUSD5 CDC7 STEAP1 LINC00621 USP1 GMNN MMGT1 LRP11 C9ORF41 SDF2L1 SYT13 TMEM47 SRSF2 METTL25 ZNRF3 LINC00973 WFDC3 MMP9 MED10 PTPRD LOC101060553 TRBC1 DPH2 ZNF337 DIAPH3 NEURL1B CSE1L SRSF6 ZNF385B HABP2 LINC00116 ANKRD13A GLMN C15ORF48 KDSR YIPF6 ZMPSTE24 ZDHHC15 MCC ATAD2 ANXA2R GALNT18 LINC01514 REEP1 BCHE RPIA NXPH1 LOC102723701 LOC100507395 USP43 CINP CEP192 CEMIP PPP3CB OTX2 TXNDC16 CENPC DENND5A PCNXL3 LGR5 LRRN4 ATP5E RND1 COL11A1 NTF3 MAGOHB ZNRF4 C3ORF52 VEGFC ROBO1 GLCE KIAA0895 PHYHIPL GABPB1 BTBD11 GNB4 CDH6 GXYLT2 LPPR5 LOC100131347 CENPL MOSPD1 CD46 SLC35G2 CSRP1 TMEM200A KISS1 CDCA7 FANCG HTR1B ITGAV UHMK1 RACGAP1P DHRS13 ELMOD1 MCM6 ZCCHC12 IL1R1 CD47 ZBED8 PRDM12 NEDD1 PCDH9 CEP76 RWDD4 KRTAP1-5 LRRN4CL NECAP1 ME2 PCYOX1L PLCB1 CHSY3 SMAD9 NIPSNAP3A EHMT1-IT1 TMEM169 MT1H SERPINB7 SARS-CoV perturbation; 217 Up Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 7 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. F2RL1 CYP11B2 EGR1 LARP1 ASAP2 CXCL10 BAG3 SNIP1 PTX3 HIST1H4A MAP3K1 SLC44A2 NEU1 NOTUM DEDD2 CEBPD RPL38 VASP PRAM1 SMAD7 SMARCD1 STAC3 SPRY2 MICU1 LINC00482 CXCL8 ZFPM1 EGR3 KLF10 SERPINH1 FOXO1 KIAA1522 GTF2IRD1 TRIM16 ZNF217 GABARAPL1 MAP2K3 MC1R FOSL2 ZNF646 PRR12 GPR162 SKAP1 RASAL3 CCL20 NPPA ADM FAP SNAI2 LRRC17 BTG2 ZFP36 LASP1 IER3 FOS GRASP DUSP1 FAM129B HMGCS1 TXNIP NFKBIA JUNB CTGF PLSCR3 JUND DDX17 PIM3 HSPH1 ERRFI1 DNAJA1 DNAJB1 MYLIP NAB1 SET MFHAS1 ZC3H12A TGFB1I1 GJA8 TNFAIP3 GPR61 ZNF35 ZNF267 CLSTN3 FILIP1L VASN BBC3 DUSP6 GPR144 NEURL3 LIF FLRT3 DUSP5 TIPARP IRF2BPL CSRNP1 SERTAD1 ZSWIM6 BHLHE40 NFKBIZ SNHG1 ZBTB34 SH2B3 SOWAHC ZNF263 UBBP2 SPRED3 PAN3 RNF151 PRKRIR SSC4D HSPA1A HMX1 IL17C RNF20 FOLR1 MXD1 ZFAND2A FAM117A MALT1 SGMS2 NCOA4 RSPO3 PDE4B EFNA1 FOXO4 ZCCHC24 TAF7 GSPT2 NOA1 RRAGC MARK4 KDM3B RIPK3 HOXA5 HACL1 ARRDC2 DLG4 CREBRF MCU MSMO1 LINC00543 FAM46B ITPKC HMGCR BLCAP MAML1 SQLE ID2 ZNF212 LHB IP6K3 PRRX2 C17ORF50 BLOC1S4 YTHDF2 ATXN1L SNAPC2 SIK1 MEIG1 EMD BTBD6 LOC101928401 LOC149401 KRTAP4-6 DNM1P41 ZNF211 RASSF10 LAGE3P1 IL34 SFSWAP TMEM115 LINC00514 DNAJB5 CTDP1 DNAAF3 B3GNT8 RBAKDN RAB40AL F10 MLXIPL LINGO1 SRD5A2 SOX15 HSD17B14 DKKL1 RASA1 PRRT2 MVD ITPRIP MUC3B ODF3B CTF1 SNX15 DEXI IFT46 ZBTB2 FAM134C LOC388210 SHROOM4 EFNA3 FOXC2 PRKAG3 MUL1 ANKRD9 PCSK1N RUNX1-IT1 ZNF671 REL LOC157860 MAP3K14 ABL2 C6ORF47 FAM189A1 LTB4R2 ZBTB22 FLJ32742 ADAMTS14 SARS-CoV perturbation; 283 Down Genes from GEN3VA; Human Vero E6 cells; Accession: GSE30589 ; Platform: GPL570 ; Entry 7 The authors used Affymetrix microarrays (Human Genome U133 plus 2.0) to compare global gene expression between SARS-CoV-infected, mock-infected and SARS-CoV-ΔE-infected cells. CCL2 HYOU1 CTSL ACADM RNPEP ANXA3 YIF1A RBX1 DDX1 AP2M1 TMEM39B PLOD2 NUTF2 TIMM10 KRT20 NUP85 THOP1 REEP6 ABHD14A CRADD C20ORF27 OCIAD2 EXT1 SH3BGRL2 EPCAM HTRA1 ACOT13 ISG20 OGDH PRPS1 UQCRC1 TGFBI SRSF9 NDUFB5 TOP2A ZWINT CDCA8 CCNA2 TK1 TROAP UBE2C KIF18B NUF2 HCCS BUB1B CDK1 MPND GSTO1 CDCA2 RMI1 CDCA3 CRIP2 CHTF18 STAT5A BDNF SRSF1 DSPP UPP1 SYTL1 CENPN CDC25C UBE2T FBXO5 CKAP2L FAM64A SGOL2 TACC3 NUSAP1 MCM5 PBK SPC25 MELK GLIPR1 NDC80 NEIL3 KIAA0101 BEX1 PSAT1 POLE2 PSMB8 GINS1 KIF18A LRRC3B UNG MITD1 NRIP3 PPY INMT ACTC1 PFN1 TMA7 GSTM5 SPARC EIF2S3 PSMB9 GDPD3 CA2 FABP5 COX7A2 CRIP1 EEF1B2 SNRPD2 NDUFA13 TAGLN PRDX5 TUBB TMEM160 DHX15 ROMO1 CAPZA2 CDO1 USMG5 DAD1 MT3 RBM24 EDN2 OLFM4 PRR16 KBTBD8 TENM2 NGF TMEM258 PIGF SLAIN1 NUP155 DEPDC7 UBE2S SNRPG HAT1 SELT GGPS1 UBE2M ISCA2 MRPL46 RRM1 MND1 ASNSD1 ATP6V0E2 C19ORF70 NDUFAB1 FAM216A MRPL27 CRYZ ARL6IP5 MIF SRM C12ORF29 PFDN2 ARMCX6 CFL2 GEMIN2 CKB AP1S1 TUBA3D L3HYPDH BRE TAF12 LSM2 TEX30 PSMB3 SRP9 TFPT CHMP4A DYNLT1 IMMP1L MAGOH PRORSD1P ICT1 MRPL42 TMEM126A CCDC58 RAB2B SAR1A TPRKB UCHL3 MRPS35 UGT8 HAUS7 YIPF3 TAF13 SUSD5 CDC7 RFC4 STEAP1 LINC00621 GMNN MMGT1 NAA10 LEO1 EIF2D LRP11 C9ORF41 NUDT9 TMEM47 SRSF2 LOC102606465 GNAZ METTL25 WFDC3 MMP9 MED10 LOC101060553 SRSF6 ANKRD13A GLMN C15ORF48 ZDHHC15 LINC01514 BCHE CINP CEMIP CENPC PCNXL3 LRRN4 COL11A1 MAGOHB GABPB1 GXYLT2 LOC100131347 CENPL MOSPD1 CD46 SLC35G2 TMEM200A FANCG ZBED8 PCDH9 RWDD4 PLCB1 MKKS STXBP1 CLEC3B NSF SPESP1 LOC158402 URB2 HIST1H3B ACBD6 MRPL47 RPA3 LOC101929084 ATP5G2 JPH1 ELOVL4 TNNT1 POTEKP RDM1 ACPT NUDCD3 SERTAD4-AS1 PCSK1 SAMD13 TRIAP1 ARHGDIG PTS FUOM TCTEX1D2 IFT88 C8G BCL2L12 PSD3 MSLN SLIRP SUPV3L1 RBP5 STAP2 SLC6A9 GMDS TCEB1 APBA3 VAMP5 ABHD10 GRAMD4 MRAP2 FLJ25758 PIGW SNHG5 TRA2B PPP3R1 GDAP1 SNRNP40 LRRC15 NUP43 SARS-CoV perturbation; Up Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 1 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. EGR1 ERGIC1 SPATA21 IFITM3 IFITM1 NFKB1 FBL OAS1 PTX3 TEX28 PCK1 PLAT OASL GGH HIST1H4B KRT17 IL33 SHISA6 CKS2 STATH PLK1 GAS2L3 TOP2A TK1 LMNB1 GTSE1 CDKN3 UBE2C NEK2 SHCBP1 CES1P1 HMMR DDIT4 SPAG5 BUB1B KIF2C KIF14 ASPM AURKA DLGAP5 RRM2 CDK1 CTSZ SAPCD2 TRPM2 CDCA2 KIF11 TPX2 STIL CCNB1 ANLN NCAPH CEP55 CDCA3 CDC20 HJURP MKI67 KIF20A NCAPG CXCL8 AKAP5 CHTF18 SERPINH1 ZFP36L2 FOXM1 FGF3 SOX9 ATF3 PRC1 PSRC1 BCL3 ASF1B KIF22 CKAP2L FAM83D NCAPD2 SGOL2 NUSAP1 PBK IFIT1 RACGAP1 SPC25 DEPDC1 MAD2L1 KCNN4 NDC80 MASTL IFIT3 USP18 IFIT2 KIF18A NFIL3 EGR4 ZFP36 IER2 IER3 FOS CHMP4B DUSP1 TXNIP NFKBIA RAMP2 JUNB JUN CTGF EIF3E NUPR1 PIM3 ERRFI1 CCL27 EGR2 PPP1R15A CPT1C SLIT1-AS1 KCNQ1DN TNFAIP3 NAPSA ZNF205 NEUROG3 GPR144 KLHL15 FLRT3 IER5 TIPARP GRK1 BAMBI CMSS1 AP1S1 PTTG1 RNF151 TCF15 ODC1 KHDRBS3 HAMP ID1 COMP C10ORF71 RND1 EMD LOC149401 B3GNT8 HIST1H3B JSRP1 FAM46A SLC22A1 CPA5 RNF139 HSCB PDGFRL SFTA3 NFE2 KATNA1 PTMS BCL2L10 ACTN4 L3MBTL4 C9ORF84 ANKRD31 ALDH3A1 BTBD2 PRKD2 LENG1 XGY2 FBLN2 DLST LOC254896 CCNB1IP1 HSPB9 LOC100132874 KRT3 SSTR5 INPP1 C3ORF27 HRES1 LBX1 LY6H RARRES2 CDH9 LOC283484 ERMN MAP1S TRPM5 HS3ST3A1 TUSC5 BRDT CST1 LOC100506082 ANKRD13B CYP1B1 MSI1 FAM185A BIN2 FAM170B LOC100130642 ASB17 HNRNPF GPR137C FGFR3 C19ORF68 XRCC1 DNAJC27-AS1 CCER1 LOC101929144 CASC1 HLA-DMB COL9A3 BFSP1 LOC100506403 CYS1 CDKN2C LBR KLF17P1 HIST1H4E NID1 LOC100240735 MDGA2 LINC01405 ZNF28 FUT5 ST8SIA5 VMO1 RTN4RL1 ANP32C LRRC42 PTPRD-AS1 LOC101928731 LOC100996425 LOC340178 RP1 FCAMR HOXC12 LMAN2L RNF182 LRGUK ATP1A3 ANKRD20A9P CPNE2 C3ORF22 LRRC16B LINC00310 GRIK4 LOC100130741 FXYD2 OMP CASS4 ZNF439 CXCL11 PHKA1-AS1 C2ORF83 MURC RGN CABP1 PCSK9 TESC NOX3 CTSV AARS DDX25 ANKRD30B LOC100130691 ATP5G2P1 LOC389332 SLC43A2 NUDT1 RCE1 TRNP1 MGC10814 CAPN14 IGLL1 IARS TPSD1 POU1F1 SARS-CoV perturbation; 228 Down Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 1 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. OR1A1 TUBAL3 TAAR9 OR1C1 INHBE GRK7 FAM215A CHRNB1 NPIPB3 NCAN FRK LINC00342 ANKRD36C ZNF850 DHRS9 SPRR1B TTC14 KCNK6 HVCN1 IFNE WNT9B OR14J1 OR5P3 OR8B2 RAB11FIP3 HCLS1 LAG3 NLRC3 CASQ2 IL36G S100A9 MOGAT1 SELE FBXO39 MRGPRX3 CLDN2 TSPAN7 C6ORF57 FAM223B OR2C1 DBIL5P2 TNFSF4 TET1 KBTBD8 MIR21 TAF1D SLAIN1 PRORSD1P VMP1 GNG12 LGALS14 NEAT1 LENG8 ACRC LINC00973 KLHL24 KDSR LOC100131347 LRRN4CL NIPSNAP3A MSLN SELL CCDC78 SNHG11 GOLGA8B PRPF39 BSN-AS2 TTLL7-IT1 LOC100133130 NPW APOBEC4 LOC100134822 MTCL1 CYP4F11 PELI2 SEPT7P9 SYPL2 CYP8B1 TXK LOC101928107 ZMYND12 LOC100130456 PVRIG MACROD2-AS1 LOC257396 DDX43 CEACAM8 SFXN3 LOC100287497 LOC100652770 PRSS2 PP14571 VNN1 TNK2-AS1 GABRE ANKRD36B BRICD5 GPR112 LINC00659 LOC730961 PLAC8L1 RP2 IFI6 TH THAP9 MCM3AP-AS1 UTS2B FNBP4 TEX14 MIF-AS1 LOC101928161 GUSBP3 OR7A5 OTUD6B GPR143 MMACHC CELF6 DOCK4-AS1 SGK494 ARRDC3-AS1 FTX PLAC1 LOC414300 SEC14L5 LOC100507670 NTNG1 STPG2 IRAK1BP1 GPRASP1 SPDYE1 TAS2R41 LOC101927948 DPY19L2P3 C17ORF47 TMEM68 PTGR2 SCARNA15 OPN1SW SLC51A PRSS1 TAAR3 TMA16 AHSA2 KIF28P GNG13 POU6F2 LOC100134445 SLIT2-IT1 PRPS1L1 LOC101927021 LY96 TRIM73 LOC100190986 TMEM132D LOC100506974 RNASE11 CXORF24 LOC100127972 GOLGA8H BZRAP1-AS1 GOLGA8A SNORA21 PSG7 LOC100128554 CTAGE1 RUSC1-AS1 PRPF38B C3ORF33 GOLGA6A ACTL7A LDLRAD4-AS1 LOC729218 PIGL LOC100130111 AFAP1L2 C9ORF135-AS1 CFHR4 LINC00472 PAQR6 CCDC38 LHFPL3-AS2 LOC100507250 TESK2 FIRRE LOC157931 SOS1-IT1 LINC00867 ZEB1-AS1 LOC613266 ANKRA2 THSD7A CCDC112 ZNF561-AS1 LOC153682 GSDMB LOC283357 LOC100131180 FBLN7 FLJ32790 ILF3-AS1 MYF6 LOC645485 LINC01003 LOC440704 PPEF1 PPBPP2 CRISPLD2 C6ORF141 C10ORF40 OR2L1P CLGN EPN2-IT1 ARHGEF7-IT1 BMPER TAC1 ADAM1A SYT16 ERV3-2 DCP1B LOC100287290 CFAP44 TDRG1 LOC100130278 CATIP-AS1 LOC157740 TMEM178A LINC01442 CAPZA3 SARS-CoV perturbation; 209 Up Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 2 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. OR6A2 IL6 GHRH CUBN EGR1 TNF IL1A TBC1D29 SLC16A8 JAKMIP1 MYRFL YWHAE ISX SLC9A3 OR1A2 PTX3 UBQLNL IFNB1 SPI1 HBM PLEKHO1 KRT5 CXCL1 RPS11 S100P RPL38 HIST1H4H TBC1D10C CES1P1 IGLV6-57 CD163L1 CXCL8 EGR3 ATF3 RSPO1 DHH OR10C1 ZNF645 BCL3 MEFV CD69 CCL20 EMR1 HIST1H2AE CYP1A1 PGAM2 CXCL3 CH25H CALML5 HCRT ARSI INHBA EGR4 TNNC2 SHANK3 FOS DUSP1 NFKBIA JUNB JUN ARRDC3 GEM CCL27 CREB5 RRAD MAGEB1 DUSP8 TRAF1 EGR2 HSPA6 PPP1R15A BCAR4 SERPINI1 KGFLP2 TNFAIP3 KLHL11 CSRNP1 SERTAD1 ZNF816 IL11 FOSB SPIN2A FOXF2 DNAJB4 LGALS14 C6ORF25 C15ORF48 MEIG1 DNM1P41 REL EBI3 HIST1H1T FAM46A IKZF3 ALDH3A1 FBLN2 SSTR5 CDH9 LINC01405 ZNF28 LOC101928731 ATP1A3 LOC100130741 TPSD1 POU6F2 LOC101928580 PRNT IDI2-AS1 CELP CRABP2 LINC00265 LINC00324 TMEM126B HIST1H3H FAM53B-AS1 C10ORF82 TSPY26P LIN28B BPIFB4 LOC100996671 MGC24103 LOC286190 ZC2HC1B STX19 NOXRED1 TSTD2 LOC338963 AGR3 GYPC TRIML1 PYY2 LOC284244 KIAA1661 LOC100132078 LINC00459 BBOX1 FAM171A1 RAB11B HIST1H4D CACNA1G-AS1 LINC01215 IL32 LOC285000 PER1 LINC00176 SIGLEC10 TOB1-AS1 LOC102723831 MADCAM1 LOC100505609 LRRC4C WFDC10B CLDN14 HIST1H2BL ASB12 RASD2 GPR101 LINC00929 LOC101929765 C2ORF76 LINC01492 C7ORF69 MROH2A DUSP9 CNGA3 GABRA3 KRTAP9-8 HIST1H4F TMEFF2 LOC645188 HIST1H2AM PROSER2-AS1 MNDA BMP10 PROL1 LOC100289026 HIST1H2BG LOC101927379 GAGE1 IL20 LOC100507513 ISL2 CD1B C16ORF78 BMP15 GPR63 AOC4P MT1X LINC01029 LINC00645 ORM1 PRR23D2 PIRT LINC00853 C6 IFNL2 CSMD3 ZFP2 SPATA25 LOC100506122 DPH6-AS1 DRD1 WDR86-AS1 APCDD1 SOX21 LHX5 C16ORF71 HIGD1B ND6 SARS-CoV perturbation; 291 Down Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 2 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. TRIM59 HRAS ACE2 GTF2F2 CENPF UBAP2 LRRC19 CIT TUBA3C CRISP3 GIPC2 HS2ST1 THOP1 DMXL1 RDH14 SAC3D1 SERPING1 PPL SLC16A7 SLX4IP ZNF850 ABLIM1 SYBU ZWINT CDCA8 VSIG10L TK1 EZH2 TUBG1 GTSE1 SHCBP1 NUF2 CDCA5 SPAG5 BUB1B KIF2C KIF14 ASPM DLGAP5 GPNMB RRM2 ORC1 KIF4A KIF15 CDCA2 KIF11 RMI1 TPX2 STIL CEP55 CDC20 SKA1 HJURP CENPU CENPW SNX8 MKI67 KIF20A DTL NCAPG CRY1 MMP1 FOXM1 GRHL2 IL20RB FRAT2 PRC1 CENPK SMC2 SLFN13 E2F8 MIS18BP1 FANCI IQGAP3 NCAPD2 SPC24 HELLS KNTC1 NUSAP1 MCM5 PBK RACGAP1 MELK NCAPG2 NDC80 MASTL RAD51AP1 BEX1 PLAC8 UNG TNFAIP6 SLC7A11 FST UBL3 CA2 PRDX5 TMEM160 CD97 GNS HMGN5 MAFF UBE2S HMGB3 RRM1 RNASEH2A TUBA3D MCUR1 UCHL3 HAVCR1 NOSIP UBE4A MSH2 VRK1 CDC7 FAM107B USP1 LAMB1 TUBB6 BEX2 FAM122B ETFB HSPA2 PCSK5 E2F7 TTC32 VPS51 MNS1 AKR1B10 EID2B KLHL24 KDSR ATAD2 TXNDC16 CENPC ROBO1 UHMK1 LOC158402 ACBD6 JPH1 PSD3 PIGW GDAP1 PIGZ GPR137C FGFR3 CYS1 MTCL1 DDX43 ANKRD36B IFI6 C3ORF33 ZEB1-AS1 LOC283357 ILF3-AS1 PSIP1 MCM4 TTF2 RECQL ALMS1-IT1 CHRAC1 CCDC28A SLC20A1 PLAGL1 C8ORF88 FAM13B FAM111B KIAA1279 CFI ZNF431 VPS41 MCM7 LOC642361 LAMP3 DCPS ZNF566 DDX60 MBNL3 ZNF791 PHACTR3 NAA40 KIAA1211 LOXL1-AS1 ABAT C22ORF39 MED29 KBTBD7 NRTN CCDC68 PRTFDC1 DIRAS3 MAN2A1 SUMF1 FAM149A DHX16 MPHOSPH9 GMCL1 ALG10B DCTD LOC100132884 PNKP C10ORF32 ACP6 N4BP2 PGBD3 ARL13B LPGAT1 ARID4A ALKBH6 RBBP5 HHAT SMC3 LOC339803 TMEM56 BBS2 CCDC152 SNRNP25 MAD1L1 DDHD2 WDHD1 LAMB2 SNRPA1 ALYREF SMG1 METRNL TPR LONRF2 DNA2 AMFR CEACAM7 ASRGL1 SLC26A2 MTIF2 SLC35E3 SMAD5 DMAP1 ZNF623 GTF2H3 CIPC RFC5 RFC2 RNF166 LOC284219 PLEKHA6 IDH2 PET117 SEMA3E GALNT12 LRRC45 NHS MIS18A PDZK1 HAUS6 HRASLS TMEM133 AHNAK2 SEC62 EOGT CCDC77 EIF3A NEB IFT74 C9ORF91 CCDC106 MED22 TRHDE EP300-AS1 GPATCH1 VPS4B LMNB2 NBPF11 CASC3 APOBEC3B LOC100129973 ADAT1 TAF1A LIG1 ASB16-AS1 RHNO1 NOTCH2NL PRPS2 SPIN4 TFPI2 LOC338620 NCAPD3 SHPRH TTC31 TMEM237 CD302 CDCA7L IMPACT C3ORF80 SARS-CoV perturbation; 267 Up Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 3 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. IL6 NMI DDX58 CREB3L3 CXCL10 IFITM3 IFITM1 MYRFL LAP3 KLF6 OAS1 PSMC6 STAT1 IFITM2 OASL IFNB1 ISG15 NTS UAP1 ARL14 MX1 MYD88 MDH1 C1D CD55 ZFAND1 MT2A CXCL1 TNFSF10 IFI27 RPS24 S100P GADD45A CKS2 ACOT13 ISG20 TOR1B APOL1 LMO2 CDKN3 NUF2 IFI44 EPSTI1 BATF2 OSTC TTK CD163L1 CXCL8 MS4A6E SYNPR HELZ2 CENPK RSAD2 OAS3 IDO1 IRF7 ZBP1 NLRC5 TAP1 CCL20 IFIT1 SECTM1 MAD2L1 CENPE MASTL IFIT3 RTP4 OAS2 PHF11 XAF1 PSMB8 CD274 APOL6 GBP4 USP18 CMPK2 IFIT2 IFI16 C5ORF28 PLAC8 IFIH1 MLKL PML NT5C3A PARP9 PARP12 SAMD9L HSH2D FAP LIPG BASP1 RNF213 IFI35 PARP14 SAMHD1 UBE2L6 TLR3 SP110 ACKR4 IRF2 PSME2 IRF1 DTX3L IRF9 PSMB9 COX7A2 IFI44L C1QBP HADH ATP6V0B NDUFA1 CCNL1 PSMA6 ANXA1 USMG5 GTF2B CCNL2 RPS27L C8ORF59 CCL27 AOC3 LOC646903 IFNL1 TRIM22 GIMAP2 DUSP5 YOD1 MIR21 ZNFX1 SNHG1 SNRPG SELT ASNSD1 GEMIN2 MRPL13 UBLCP1 TEX30 WASH3P GOLT1B GSKIP EMG1 MRPS23 COMMD8 NUP37 MOB4 STEAP1 PDCD10 PNPT1 ITGB3BP UBA3 NEK7 SLC25A46 ZFAND2A DNAJB9 NEAT1 LENG8 TAPT1-AS1 LINC00973 C15ORF48 SNHG5 TMEM27 CASP1 PPM1K TRIM21 TRIM5 ZUFSP TDRD7 CXCL11 ATP5G2P1 GOLGA8B GABRE AHSA2 GOLGA8A ERV3-2 TMEM178A IDI2-AS1 C10ORF82 AGR3 PYY2 LRRC4C GABRA3 MNDA GPR63 IFNL2 SPATA25 LAMP3 DDX60 APOBEC3B ACN9 LOC441179 SLC25A28 TIA1 ZNF257 SELO DNAJC7 KIFC2 ACTL9 DKFZP586I1420 BET1 GBX2 STARD4 NPR2 ZBTB6 CHAC2 CAPN8 RNF19B C19ORF66 LGALS9 TNFSF13B NPIPA1 UCN2 FASTKD3 PPIL1 SCGB1C1 CAB39 XRN1 LOC727820 MRPS11 SP100 CASP16 C10ORF99 SCOC NRD1 LRIF1 ORC4 CT83 OVOS2 MIR22HG STX16 RARRES3 HNRNPA2B1 ZNF302 SLC35A1 BCL10 MX2 IFIT5 HERC5 METTL4 TRANK1 RBMX RPL22L1 CD58 ANKRD49 C17ORF67 GORAB DDX60L PSMB8-AS1 ZRANB2 LINC00276 TMEM140 HNRNPU-AS1 PILRB HYAL4 EFHC1 UFM1 ADRB2 C12ORF60 SAMD9 DKFZP434I0714 USP26 SH3PXD2A-AS1 C4ORF36 USP44 CTSLP8 GBP1 SNHG12 CASP7 SARS-CoV perturbation; 233 Down Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 3 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. CEP350 HECTD1 TRIM59 LARP1 KPNB1 ATP6V1A EP300 GOLGA2 EHBP1 F5 INHBE TP53 NUTF2 RBM41 ERC1 VPS13B FAHD1 CISD1 SAC3D1 HOXC6 RASEF TMC5 CP AK4 THRB SH3RF1 KIF21A NFAT5 TEAD1 RASSF6 SLC16A7 SLX4IP ZNF850 SGPP2 ABLIM1 CCND1 KCNK6 STT3A TMBIM6 ASPM CDC6 ORC1 PAPSS1 KIF3A HINT3 TRAK2 CDH1 CSNK1G1 NCOA3 GRHL2 TRIM16 FZD8 EFNB2 CASP2 TAS2R9 CLCN5 NCAPD2 SPC24 SGOL2 CLDN2 ICAM1 GLTP GPAM LYZ MYH10 DDX17 GNS ZFP91 TRUB2 MFHAS1 TGFB1I1 LCE2B FAM154A TET1 TLCD2 DEPDC7 LIAS HAVCR1 GNG12 CTSO BBS5 FOLR1 MXI1 PCSK5 USP10 APOBEC3C ANKRD1 HIST1H4C PPP1R2P9 MIR663AHG HCG11 UHMK1 PSD3 CYS1 NPW IFI6 IRAK1BP1 SNORA21 C3ORF33 LOC283357 ILF3-AS1 LOC100130278 FAM111B LOXL1-AS1 NRTN LPGAT1 RBBP5 SMC3 ALYREF SMG1 TPR SMAD5 ZNF623 GTF2H3 SEMA3E NHS AHNAK2 EP300-AS1 ADAT1 PRPS2 C3ORF80 RBM27 LOC400043 ST3GAL1 MLEC KIF3B CCNT1 ZNF573 FOXD1 CHD4 ZNF461 LOC100506699 GLG1 CEP104 TAF3 REC114 CBX5 NOL9 TOP1 KCTD12 PDPK1 SLC47A1 SPAG9 KIAA1033 PRRC2C MECP2 KIAA0100 SECISBP2L TTC3 C1ORF174 TMEM159 GTF2I APPL1 SYNJ2BP TMEM107 JPX PPP1R3D CKAP4 GLIS3 PDCD7 NIPBL BBX CNNM3 ASB8 PMCH CCDC186 RASGEF1C CDC42EP5 ZBED6 PSTPIP2 CCDC42B WSB2 KBTBD6 KPNA6 UTP20 KANSL1-AS1 KIF1A KDM5A PIK3R1 TNRC6B FBXO33 SCRN1 CRKL TULP4 GARS PAQR8 SMIM10 GJB2 IQCJ-SCHIP1-AS1 PCYOX1 UBN1 NDUFS1 DNAJC22 LOC101928909 ZNF713 LOC100287525 TMEM181 NDRG3 DNAJC3 C1ORF210 UCP2 PNMAL1 CENPBD1P1 LOC100505501 LIPH OIP5-AS1 MEIS2 EIF5B PPP1R9A ZBED1 CORO2A SPAST SMC5 SMURF2 PAPSS2 ATRX LTN1 CRIM1 GINM1 LOC400464 DIS3L ASH1L IGF1R RPL13P5 GALNT11 SIKE1 RUNDC1 PROSER3 SRGAP2C ENTPD4 POGK CLUAP1 YY1 SARS-CoV perturbation; 189 Up Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 4 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. CSNK2B SLC6A18 DDX5 TRIB3 YWHAZ ASAP2 SLC30A9 FBLN5 RNF41 TUBA1A AGPS PSMC6 PXN HS6ST2 ATP6V1B2 ZFAND1 DEDD2 ITGA2 ADH7 PRPS1 PIP5K1C C1ORF162 MTCH2 HCCS PDGFC H1F0 IL18 CDKN2B SKA1 MTHFD2 LINC00612 C1ORF106 CBFB POU4F3 ULBP1 FAM132B PSAT1 PLAU FST DPYSL2 CLIC4 CDC42EP1 IRF9 C1QBP HADH ATF4 ATP6V0B RAB11A RNASE6 ART4 SULT1E1 DUSP5 ERI3 GTF2E1 UBLCP1 UBE2E2 DNER SDHAF2 TTYH1 EMG1 NDUFA8 HSD17B2 PCMT1 SLC10A3 VAMP7 MAP4K3 MMADHC CERS2 ZFAND2A AFTPH ZBTB8A ODC1 GFM2 HAMP TPST2 JSRP1 SFTA3 NFE2 DLST HSPB9 KRT3 INPP1 ERMN BRDT MSI1 BIN2 RNF182 LRRC16B IARS PHACTR3 SELO CAB39 UFM1 EIF2B4 LINC01209 CARM1 SLC22A4 LINC00487 RRH RBM18 RALB PEBP4 LINC00597 ZBTB46-AS1 IGSF11 XPOT BOP1 FLJ31356 METTL2B LINC01087 TCTA CETP ENTPD3-AS1 OR51A1P SEMA3G UGT2B28 CYSRT1 LINC00536 LOC100131053 LOC100129620 CYP4Z2P LINC00337 ARMC2 ACOT7 LPCAT1 TAC4 FAM103A1 WFDC12 TTC8 SCT ZNF624 ZNF468 LOC101929524 TRAM1L1 PCDHB5 THNSL1 KRTAP4-4 EID2 AADACP1 LAMC2 MLF2 IQCF4 TUBB7P LOC101927354 LL0XNC01-116E7.2 FEM1C LOC340340 NUDT16P1 LOC101929450 ABCA11P LOC729680 TPRA1 FLG2 YTHDF3 MEIS3P1 NUS1P3 LOC497256 LOC400548 CCDC173 PJA1 LRRC31 IGFBP1 TYW1 PKIB REEP4 TP53BP2 CCDC91 FUT8 DBR1 ZNF571 SH3BP4 KRT16 CHUK XRCC4 ZNF304 SAP30L-AS1 LINC01019 FAR2P2 CDIPT-AS1 MIR4500HG CXORF30 DEGS2 PRKACB GFPT1 LOC283075 EMP1 MB21D2 TWISTNB PIP4K2C SARS-CoV perturbation; 311 Down Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 4 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. PRAC2 CYP11B2 HECTD1 TRIM59 KPNB1 CRYGD EP300 CRYGA CWC27 GUCA2B SSX5 CDX2 HOOK1 DYNC1H1 GOLGA2 EHBP1 AASS RBM41 PPIG NPIPB3 VPS13B CISD1 RASEF TMC5 CP FAM114A1 TNFSF10 KIF21A NFAT5 TEAD1 RPL38 RASSF6 TET2 SLC16A7 ANKRD36C SLX4IP MALAT1 ABLIM1 TTC14 EXO1 GAS2L3 TOP2A CCNA2 LMO2 LMNB1 SHCBP1 KIF18B STAC3 ASPM KIF15 FER1L4 PKMYT1 TRIP13 CDC42BPA NCAPG TGFBR3 HINT3 KLF13 CSNK1G1 NCOA3 TMEM184A SLC9A2 IFNE NFIC ATOH1 PSRC1 TMEM88 TMEM207 CLCN5 CUEDC1 GLT1D1 SLFN13 SPC24 HELLS SGOL2 NUSAP1 SPC25 ZNF442 MOGAT1 CST9L XAF1 GINS1 PLEKHA4 CLDN2 GBP2 ARC SAMD9L CSTA TLR3 GCKR PLTP TSPAN7 GPAM MYH10 RP9 ACTA1 ADAMTSL2 EIF3C MFHAS1 SPANXA2-OT1 MAGEA12 FAM223B CAPSL CCL26 EGR2 MLLT4-AS1 KGFLP2 HDAC9 TMEM151A TLCD2 LOC100289333 ZNF367 NFKBIZ GNG12 CTSO PTMA FOLR1 SOSTDC1 USP10 RSRP1 ANKRD1 LOC100286895 NEAT1 HIST1H4C MIR663AHG BLID HCG11 CDCA7 UHMK1 SMAD9 EHMT1-IT1 RASSF10 PRRT2 C8G PSD3 SLFN5 RBM43 INSL5 NPW LOC100134822 ANKRD36B IFI6 MCM3AP-AS1 MIF-AS1 SCARNA15 LOC100134445 SLIT2-IT1 TRIM73 LOC100127972 GOLGA8A SNORA21 RUSC1-AS1 LINC00472 FIRRE LOC100131180 ILF3-AS1 BMPER ADAM1A ERV3-2 LOC100130278 BBOX1 CACNA1G-AS1 LOC100289026 LINC00853 ND6 FAM111B SMC3 ALYREF SMG1 TPR SMAD5 EP300-AS1 ADAT1 TAF1A C17ORF67 RBM27 LOC400043 MLEC TOP1 KIAA1033 PRRC2C KIAA0100 SECISBP2L TTC3 TMEM159 SYNJ2BP JPX GLIS3 PDCD7 BBX CNNM3 CCDC186 ZBED6 KANSL1-AS1 KIF1A FBXO33 PCYOX1 UBN1 NDUFS1 DNAJC22 TMEM181 MEIS2 EIF5B SMC5 ATRX LTN1 GINM1 MTPN FNIP1 ATAD5 ANKRD12 SHANK2-AS3 HOXA6 FAM110C RNF145 DCST2 LOC400958 P2RY1 ST6GALNAC6 ZNF223 ZDHHC8P1 GLP2R LOC100130078 BBS4 CEP290 SNORA71B HERC1 TM6SF1 BOD1L1 ZNF567 MAP3K14-AS1 LINGO2 RFWD3 TGS1 LOC440982 ZNF321P LENG9 RSRC1 BCO1 PNISR PPP1R10 THOC2 LHFPL3 MIR30C2 BTK COA7 HIST1H2BO SDAD1 FAM179A HSD17B7P2 FMNL2 THRAP3 LINC00485 LINC01106 TAF15 SEMG1 MIA2 RASL10A NPSA PKHD1L1 CCDC160 SCAMP1 OCLM MRGPRF CELF2-AS1 CAPN12 LOC100131662 ONECUT2 TMEM238 GPR128 LOC100130872 DGKH NAA25 MMEL1 LOC100128988 CCIN LOC100996255 LOC101927746 RSF1 TCEAL3 LOC147791 RFX7 LOC100505650 AGBL2 LOC399884 HNRNPL C9ORF43 DKFZP434J0226 TRPV1 CHRM3-AS2 C18ORF42 C1ORF94 GHET1 FOXC1 LINC01184 LINC01207 SH3GL1P1 LOC729732 SRRM2 SLC25A36 LOC100130458 DEFB123 DEFB132 CCDC142 LIMA1 ESCO1 PAXBP1-AS1 FLJ36848 HPS5 MYOD1 ORC6 SARS-CoV perturbation; 311 Up Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 5 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. RSRC2 IL6 CCL5 EGR1 NMI DDX58 IL1A CXCL10 IFITM3 CYP2J2 IFITM1 MYRFL NEDD9 LAP3 KLF6 SNIP1 OAS1 PTX3 STAT1 IFITM2 EIF2AK2 OASL MOV10 CXCL2 IFNB1 ISG15 MARK2 MX1 MYD88 NR3C1 KMO MT2A CXCL1 TNFSF10 IFI27 KRT17 DUSP16 NR4A2 SEMA3A HIST1H4H TJP1 ISG20 CMTR1 TOR1B THBS1 BST2 SLC15A3 SMAD7 FBXO6 LMO2 IFI44 MT1F EPSTI1 BATF2 LINC00944 CXCL8 ZNF600 G0S2 PTGS2 EGR3 KLF10 PLAUR GPR87 TRIM16 ATF3 RXFP2 BCL3 HELZ2 SBNO2 RSAD2 OAS3 CD69 IDO1 IRF7 ZBP1 NLRC5 PLA1A DUSP2 TAP1 CCL20 IFIT1 HIST1H2AE CD96 MASTL CYP1A1 PLIN1 IFIT3 RTP4 OAS2 PHF11 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 CCR1 GBP4 USP18 CMPK2 IFIT2 CCNE2 IFI16 PLAC8 IFIH1 PML PLEKHA4 NFKBIE NT5C3A PARP9 PARP12 ARC SAMD9L HSH2D NFIL3 FAP LIPG INHBA RNF213 IFI35 PARP14 TRAFD1 SAMHD1 EGR4 UBE2L6 TLR3 WARS SP110 ACKR4 RIMKLB IRF2 PSME2 KLF4 FOS IRF1 PSMB10 DUSP1 HMGCS1 ICAM1 DTX3L NFKBIA JUNB PSMB9 JUN IFI44L C11ORF96 SERPINB9 NUPR1 ARRDC3 CCNL1 THEMIS2 NXF1 GEM CREB5 RRAD NPFFR2 ZC3H12A DUSP8 EGR2 IFNL1 HSPA6 PPP1R15A TRIM22 B3GNT5 TET1 TNFAIP3 HDAC9 KLHL11 ANO3 GIMAP2 TIPARP CSRNP1 MIR155HG SERTAD1 TSC22D2 SERTAD2 ZNFX1 IL11 FOSB VMP1 PNPT1 CCDC117 DNAJB4 DNAJA4 DUSP10 HAMP ITPKC MAP2 C15ORF48 CEP76 MT1H REL MAP3K14 TAP2 TMEM27 SLFN5 CASP1 IL15RA TRIM21 FAM46A ZC3HAV1 TRIM5 TDRD7 IL15 IKZF3 IRAK2 PRKD2 LOC283484 CYP1B1 HIST1H4E NID1 CXCL11 FAM53B-AS1 STX19 HIST1H4D IL32 PER1 SIGLEC10 HIST1H2BG MT1X PRR23D2 IFNL2 DRD1 LAMP3 DDX60 SLC25A28 GBX2 ZBTB6 C19ORF66 LGALS9 TNFSF13B XRN1 SP100 RARRES3 MX2 IFIT5 HERC5 DDX60L TMEM140 HNRNPU-AS1 ADRB2 SAMD9 USP44 GBP1 SNHG12 CASP7 TPRA1 TP53BP2 HIST1H2BO LOC145474 CD83 SNHG9 HES4 ETS2 IL17B UGT1A6 OSR2 CEACAM1 MAP10 PLK2 LOC100505478 RBM34 RFPL3S KLHDC7B WEE1 ZNF649 ALDOAP2 C3ORF35 AFF4 FBXW11 LINC00520 CDK17 LOC284912 LINC01350 HDX RELB MT1HL1 LOC100507194 TAF1L RCAN1 SIDT1 ETV7 HOMER1 GPT2 BTN3A3 DEFB127 GMPR CPEB2 MICB CHST15 CFLAR-AS1 BAZ1A NFE2L3 SLC22A24 LINC00896 CLUHP3 ZNF213-AS1 ZNF426 CTNNAL1 PMAIP1 HCG26 MTNR1A LOC100130428 TICAM1 OXTR CX3CL1 LOC285422 CASC23 SLC28A3 KIR2DL5A HLA-DRA SARS-CoV perturbation; 189 Down Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 5 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. MPHOSPH10 HSPA5 HYOU1 TRIM59 LARP1 ERGIC1 RBL2 ACE2 YWHAB SLC22A18 NDRG1 HOOK1 UBAP2 LRRC19 F5 TUBA1A CLRN3 ANXA13 TST AGT LGALS4 PLAT SEPHS2 FAHD1 CISD1 ACO1 ALDH8A1 CAMLG CEACAM6 TMC5 AK4 SH3RF1 PPL SLC16A7 SLX4IP FOXQ1 ABLIM1 SPRR1B STT3A ITGB5 CTSB LGALS1 ASPM GPNMB CTSZ LTA4H PAPSS1 CRIP2 KIF3A TFDP2 HINT3 MMP1 TRAK2 MLPH BCAS3 ABI3BP MOGAT1 MAB21L3 RNASE4 CLDN2 RASA4 SLC7A11 TMA7 TXN GPAM LYZ MYH10 PRDX5 RBM3 SERINC3 BNIP3L TLCD2 CYP4F3 ANP32A UBE2S PJA2 CRYZ ARL6IP5 AP1S1 C12ORF57 BFAR MAGED1 HSD17B2 MGLL SLC39A10 CXXC5 ETFB MXI1 HSD17B11 SERINC5 HIST1H4C EPB41L4A-AS1 AKR1B10 HCG11 LINC00543 FAM129A ROBO1 UHMK1 PSD3 SNHG5 PPP3R1 TFF2 ACTN4 CYS1 LOC257396 PRSS2 ANKRD36B IFI6 TH MIF-AS1 PRSS1 ANKRA2 LOC283357 CLGN FAM13B SUMF1 GMCL1 C10ORF32 LPGAT1 HHAT ALYREF LONRF2 CEACAM7 SMAD5 IDH2 NHS AHNAK2 NEB ADAT1 PRPS2 LOC338620 CDCA7L LOC400043 MLEC KCTD12 PDPK1 SECISBP2L TTC3 TMEM159 BBX CNNM3 KANSL1-AS1 TNRC6B SCRN1 PCYOX1 NDUFS1 DNAJC22 ZNF713 LOC100287525 DNAJC3 PAPSS2 LTN1 RPL13P5 RNF145 LENG9 ONECUT2 SLC25A36 CCDC47 DUSP4 TMEM57 PRRC1 NT5DC1 SLC2A10 RRAGD VAT1 ZNF581 NPY1R RALBP1 ARPC1B LETMD1 NOSTRIN SLC35E2 PRSS3 FAM210B RPL23AP32 COPG1 LOC100147773 SEC31A ZBED5-AS1 ANP32B ERICH5 NEFL NICN1 GLUD1 KLHDC2 SNX12 MARVELD2 CSTB PMM1 SARS-CoV perturbation; 402 Up Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 6 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. SEC16B BIRC3 IL6 IFNA1 CCL5 EGR1 NMI DDX58 IL1A CXCL10 IFITM3 CXCL16 CYP2J2 IFITM1 PLEKHF2 HLA-B LAP3 JAK2 KLF6 OAS1 PTX3 HLA-DRB1 STAT1 TRIM25 IFITM2 EIF2AK2 TMEM173 APOBEC3G OASL TRIM31 MOV10 CXCL2 IFNB1 NPIPB3 ISG15 FRMD3 MARK2 NUB1 MUC13 ARL14 MX1 MYD88 LIFR CD55 FZD5 BCL2A1 SERPING1 MT2A CXCL1 TNFSF10 IFI27 SIX1 KRT17 IL33 CXCL17 OSMR CFH RICTOR C1ORF116 RND3 SEMA3A ADAM28 ISG20 EHF PLEKHS1 CMTR1 PTGER4 PARP10 LGALS3BP TOR1B APOL1 TYMP BST2 SLC15A3 HLA-E FBXO6 LMO2 SLC16A1 GLRX STS IFI44 MT1F RBBP8 EPSTI1 SLFN11 BATF2 LIPA CXCL8 ZNF600 PLAUR IMPA1 KITLG ATF3 MAP2K6 HELZ2 OGFR RSAD2 OAS3 IDO1 IRF7 CFB ZBP1 NLRC5 PLA1A TAP1 CCL20 IFIT1 SECTM1 FYB CTSS MASTL IFIT3 RTP4 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 CCR1 GBP4 DHX58 C1R TREX1 USP18 CMPK2 IFIT2 IFI16 PLAC8 IFIH1 MLKL LGMN STAT2 PML PLEKHA4 NFKBIE ADAR NAMPT GBP2 NT5C3A PARP9 PARP12 SAMD9L GCH1 HSH2D XDH IFNA4 FAP LIPG IL4I1 INHBA RNF213 IFI35 PARP14 SOCS1 TRIM6 TRAFD1 SAMHD1 EGR4 UBE2L6 TLR3 UBA7 WARS SP110 ACKR4 RIMKLB IRF2 PSME2 KLF4 LY6E IRF1 PSMB10 RASGRP3 TGM2 ICAM1 DTX3L NFKBIA IRF9 PSMB9 GBP3 IFI44L SERPINB9 NUPR1 ARRDC3 CD74 CCNL1 DNAJA1 PSMA6 THEMIS2 SAT1 GTF2B IFNL1 PPP1R15A TRIM22 ART3 TNFAIP3 ZNF267 GIMAP2 NEURL3 TIPARP MIR155HG MIR21 NFKBIZ ZNFX1 CHMP5 DYNLT1 LYSMD2 PNPT1 TMEM50A DHRS2 CCDC109B MXD1 DNAJB4 GPBP1 DNAJB9 CADPS2 NEAT1 TNFSF15 PRR15 MAP2 C15ORF48 GNB4 CD47 NEDD1 MT1H TAP2 TMEM27 SLFN5 CASP1 PPM1K IL15RA ZCCHC2 GCA TRIM21 TAPBPL FAM46A ZC3HAV1 SELL TRIM5 TDRD7 TRIM14 PCGF5 TRIM69 MAP3K8 IL15 MORC3 AZI2 CD38 PDGFRL PRKD2 CXCL11 GOLGA8B GABRE GSDMB IL32 MT1X IFNL2 LAMP3 DDX60 CCDC68 DIRAS3 METRNL APOBEC3B SLC25A28 TIA1 STARD4 ZBTB6 RNF19B C19ORF66 LGALS9 TNFSF13B CAB39 XRN1 SP100 MIR22HG STX16 RARRES3 MX2 IFIT5 HERC5 TRANK1 DDX60L PSMB8-AS1 TMEM140 HNRNPU-AS1 ADRB2 SAMD9 USP44 GBP1 SNHG12 CASP7 LOC340340 BCO1 MIA2 FOXC1 HES4 ETS2 CEACAM1 KLHDC7B CDK17 HDX RELB MT1HL1 SIDT1 ETV7 GPT2 BTN3A3 GMPR MICB BAZ1A NFE2L3 PMAIP1 TICAM1 CX3CL1 SLC28A3 HLA-DRA ARL5B NUDCD1 PATL1 NAPA GRAMD1C PROCR STYK1 ERAP2 SP140L ACHE MDK C5ORF56 RHBDF2 NMUR2 MTF2 APOL3 N4BP1 NCEH1 ATP10D FAM122C SMCHD1 RBMS2 WHAMM B3GALNT1 TMEM62 BTN3A1 C1S PLSCR4 FLJ32255 LOC101927027 HCP5 GPR115 SOD2 MOB3C IFNA16 VNN2 HLA-DPA1 CBR3 PANX1 IRS1 CHSY1 THAP9-AS1 TRIM38 LOC100288911 JADE2 FAS RABGAP1L PARP8 IFNA2 SH3KBP1 TRIB2 MVB12A FUT4 BPGM BLZF1 IFNA14 FMR1 BTN3A2 IL12A SCAMP1-AS1 IL7 PXK LOC344887 BLNK BTC IL18R1 FAM65B OR52K3P PARP3 NAPSB PHACTR4 SLC19A3 PIK3AP1 COG3 OPTN CFLAR ZBTB33 C8ORF4 GTPBP2 RNF149 TRIM26 RAB8B SARS-CoV perturbation; 98 Down Genes from GEN3VA; Human bronchial epithelial 2B4 cells; Accession: GSE17400 ; Platform: GPL570; Entry 6 This study examined the dynamic innate immune responses of human bronchial epithelial cells against SARS-CoV and DOHV infection. ERGIC1 NDRG1 PMEPA1 TUBA1A CRISP3 CLRN3 ANXA13 ACO1 SAC3D1 EIF4B NBEA DANCR SLC16A7 SLX4IP ABHD2 TOP2A CDKN3 UBE2C LGALS1 KIF14 ASPM SAPCD2 CDCA3 CDC20 PAPSS1 KIF20A NCAPG CRIP2 TRAK2 SHISA2 NCAPD2 SGOL2 NUSAP1 RACGAP1 CLDN2 PCOLCE2 DPYSL2 GLTP MYH10 DDX17 BNIP3L CLN8 PFKFB3 HMGB3 AP1S1 MAGED1 HAVCR1 MXI1 SOSTDC1 SERINC5 ZMAT3 HIST1H4C MNS1 AKR1B10 HCG11 UHMK1 HIST1H3B PSD3 CYS1 C8ORF88 LONRF2 ASRGL1 SMAD5 IDH2 SEMA3E AHNAK2 NEB C3ORF80 CBX5 KCTD12 SECISBP2L TMEM159 KANSL1-AS1 PCYOX1 NDUFS1 ZNF713 TMEM181 UCP2 PAPSS2 RRAGD VAT1 NOSTRIN SLC35E2 ANP32B NEFL NMU HOGA1 ARSE GALM BRI3BP SERPINA6 CA9 ENO2 GRIN2A PANK1 TM7SF2 CERK CMTM4 SARS perturbation; 280 Up Genes from GEN3VA; Human PBMCs; Accession: GDS1028 ; Platform: GPL201 This study performed expression profiling of peripheral blood mononuclear cells (PBMC) from 10 adult patients with severe acute respiratory syndrome (SARS). Results provide insight into the host immune response to the SARS coronavirus. UBB PPBP CD14 EIF3F RPL12 TSPO CCND3 ANXA3 PF4 PKM ANXA2 GABARAPL2 HLA-B GNG5 UBA1 TUBA1A ANXA11 GPX1 CRISP3 PSMD4 CFP HBD HLA-DRB1 B2M CYB5R3 FAU MGAM PRKAR2B TGFB1 MTCH1 CAT PLP2 RAB5C TLN1 ENO1 RPS17 RPL37A RPS26 CEACAM6 RPS16 CEBPD RPS11 RPL41 RPL37 S100P HIST1H2BK COX6A1 RPS15 HIST1H2AC SLPI LCN2 RPLP1 RPS14 RPL27A CD24 MAN2B1 ITGB2 TNFAIP2 PGD GSN ALOX5 CYBA ITGAM TKT EMP3 GRN HK3 ZYX SLC11A1 TIMP1 CAPG CTSB CREG1 RNASE2 LGALS1 H1FX CAPNS1 RRM2 GSTO1 GAPDH LTA4H LGALS3 COX5A DYNLL1 HP TPI1 RNASE3 TYMS CHI3L1 G0S2 TCN1 CLC CAMP SLC2A3 MANF ELANE CTSG PLAUR LTF ITGA2B CLU LAMP1 MMP8 CD63 SORL1 FCN1 CEBPB PHC2 PYCARD CORO1A COTL1 CFD S100A9 IL1R2 HBB SLC4A1 SNCA VCAN TCIRG1 NFIL3 BASP1 ARG1 C5AR1 CSTA TSC22D1 FTH1 RPL28 RPS28 PFN1 RPL8 YBX1 ACTG1 YBX3 ATP6V0C SGK1 RHOG TXN NFKBIA SPARC CHCHD2 CA2 NGFRAP1 H2AFZ CST3 CRIP1 CTSH RPS10 COX8A S100A6 SH3BGRL3 JUND RPL18 VIM FHL1 OAZ1 PSMB4 TYROBP IFI30 ATF4 TALDO1 CD97 NDUFC1 ATP6V0B CFL1 ARF1 LAPTM5 RAB11A ALOX5AP ANXA1 GYG1 HCK THEMIS2 NCF4 GNG11 RPS3 VCL S100A10 PGRMC1 BPI PPP1R15A PADI4 PGLYRP1 CYP4F3 IRS2 TMEM258 VAMP3 S100A11 HSP90B1 PGAM1 PARK7 RABAC1 PSMB3 FLOT2 UQCRQ SLC25A5 SSR4 UQCRH TMSB10 TAX1BP3 ODC1 MMP9 ATP5E HLA-G S100A8 TLR2 CSF3R GCA F13A1 POU2AF1 WAS RGS10 FPR1 NFE2 CEACAM8 HIST1H3H MNDA ARPC1B RPL23A SERPINA1 ALDOA U2AF1 GNB2L1 PYGL C20ORF24 LILRA3 RSU1 SERF2 CTSA SRGN PACSIN2 AMPD2 SEC61B ACTN1 MYL6 MSRB1 CNPY3 FCGR3B EIF4A1 MMD ALDH2 COPE FBXO7 PF4V1 CLIC1 PTGS1 NDUFB4 DYSF DEFA4 NRGN ARPC4 TAF10 UQCRFS1 CHP1 RAB31 MTX1 AZU1 COX5B BLVRB GPSM3 MS4A3 UQCR11 TCEB2 EIF1 MYL9 PRTN3 PTPN6 R3HDM4 SNN RNASET2 ILK HMGN2 MAP3K7CL CSF2RB SERPINB1 PDXK MPO FOLR3 SERP1 RNH1 CDA SARS perturbation; 220 Down Genes from GEN3VA; Human PBMCs; Accession: GDS1028 ; Platform: GPL201 This study performed expression profiling of peripheral blood mononuclear cells (PBMC) from 10 adult patients with severe acute respiratory syndrome (SARS). Results provide insight into the host immune response to the SARS coronavirus. JAK1 RPS27A RSRC2 CCL5 CSDE1 DDX5 YWHAZ MACF1 RBL2 RHOA IFITM1 HSP90AA1 ATM HLA-C BIRC2 STAT1 HLA-A IFITM2 ITGA4 ITM2A NPM1 MAT2B CD8A HSPA8 PPIA RBM39 EIF4B PFDN5 POLR2B LCP1 RPL21 TNFSF10 RPL9 RGS2 RPL14 RPS15A RPL6 RPS3A RPL30 RPL23 RPL13A RPL24 RPS25 RPL19 ABLIM1 RPS29 RPL7 RPS27 CD81 IFI44 BCL11B CD247 ARL4C IL7R KLRB1 CST7 RUNX3 CDKN1C CCL4 GATA3 KLF2 TRAM1 IL18RAP TGFBR2 ZFP36L2 EEF1D LEF1 TCF7 HNRNPK CBFB KLRD1 CD48 IL10RA NKG7 CTSW LCK IL2RB GZMA CD3D LPXN CX3CR1 STAT4 PTPRC CD2 TBX21 GZMK CTSS FCER1G MYOM2 OAS2 CYBB IFI16 GCH1 PTGES3 FOS DUSP1 TXNIP EIF2S3 DAZAP2 RPL5 RPS19 EIF3E S100A4 RPS4Y1 RPL10A LUC7L3 BTG1 RPS5 NACA GDI2 RPL22 GABARAP IFI44L LITAF LAPTM4A MORF4L1 MATR3 DDX3X FNTA PDCD4 MBNL1 CD74 RPL35 PCNP CNBP RPL15 SEPT7 IL2RG STK38 EIF4A2 YTHDC1 CD164 SLC38A2 DEK CLEC2B CCND2 CELF2 IKZF1 SPON2 UBE4A HDAC1 CAP1 BUB3 HMGN4 RPL34 LDHB ID2 PRF1 CASP1 SELL FAIM3 SLC20A1 TIA1 HNRNPA2B1 HLA-DRA VNN2 BTN3A2 FAM65B RAP2B SF3B1 CCR7 KHDRBS1 XPO1 CD52 SARAF CASP8 LOC399491 S1PR1 CD53 SRSF11 CDKN1B PRKCH SNRNP200 GZMB RPS6 HNRNPA1 EIF4G2 MBD2 COX6C AKAP11 SMARCE1 PPP2R5C ROCK1 RPL17 GNLY SNRPB2 RNF6 ITK SEPT9 KLRK1 NONO LTB CALM2 ADAM10 CRLF3 ACTR2 PLEK LAIR2 SON ERBB2IP MS4A1 PRKAR1A PUM2 CAST XIST SRSF5 TRAF5 GPR56 RPL36A RAB29 KLRF1 DYRK1A ARHGEF3 LPAR6 CD44 ACTR3 RASGRP1 HLA-DPB1 ADD3 ST6GAL1 SARS perturbation; 201 Up Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 1 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. GHRH NOX4 TGM4 EGR1 UBD HIST1H1C CXCL10 PRR15L CSF2 CLDN10 CEACAM6 HIST1H2BH TNFSF10 LMO3 CFTR MSMB LRIG3 HIST1H1E PTGFR SLX4IP HIST1H1D FMO2 FZD2 AMPH BCL11B TNFRSF10C CCL4 NOTCH1 SERPINH1 BMP4 DMRT3 EGFL6 INPP5D NR2F2 PTH2R GSC DACT2 E2F8 IDO1 IFIT1 FAM78A CD86 CA7 IFIT2 MMP12 FOS DUSP1 ID3 IFI44L ZNF692 BEST1 GUCY2F LYPD6 TENM2 FLJ13744 KIAA0408 GDPD1 ZFP14 BCORL1 LOC728705 KDELC1 CXXC5 VAV3 EVPLL ID2 IP6K3 CDCA7 ZBED8 SAMD13 PNPLA3 PNPLA5 BCL11A SLC23A3 NFE2 NTNG1 IL32 HIST1H2BL MROH2A HIST1H4F ZFP2 LHFPL3 HIST1H2BO IL7 PANK1 CCR7 CSRNP3 ZSCAN31 HOXC9 EFS TLX1 B3GNT1 ZSCAN4 NAV1 RBBP8NL PLGLB1 GPRC6A KANSL1L HEXIM2 PP12613 CCDC178 GUCY1A3 CUX2 ZNF382 ZNF233 ZNF70 GLCCI1 GRAMD2 ZNF397 RCOR3 SESN1 UGT2B15 MAST3 SPTSSB CDON HIST1H2BF LOC728743 SKIDA1 A1BG-AS1 CCDC110 LINC00269 ATP1A1-AS1 SIRT4 RGS17 LYG1 SLURP1 ITGAD LOC157562 SLC6A7 ZNF404 P2RY10 ARMCX1 SIX3-AS1 LINC00599 P2RY6 PDE7A ZNF546 LOC100288893 DISP1 MEX3B TAS2R60 ZNF221 SLC25A42 ADAMTS5 MEX3A IGIP THAP2 CEP152 GRIN3A HSPA1L ZNF280D LOC100505940 BTBD8 BMF ZNF285 RAD52 KLHDC8B SOBP ITPRIPL1 ZFP82 PIK3R3 ATF7IP ZNF177 LINC01093 LINC01410 LGALS8-AS1 XKRX BANP ZNF610 TPTE2P5 KLK7 EVI2B NBPF10 MRGPRX2 FLRT2 GNE SALL2 PRO1804 NBPF9 CACNB2 KCNE3 AKAP3 MNX1-AS1 ZKSCAN3 RIMBP3 GAS1 MRGPRE SWT1 HEYL ACTA2 HERC2P2 KBTBD3 LINC01116 FLI1 RASSF4 OR2M2 PIANP HIST2H4B LINC00643 HCN3 LINC01232 NAPEPLD SARS perturbation; 299 Down Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 1 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. ADAMTS1 BIRC3 MALL SLC4A9 TRIB3 DDX21 HSD11B2 EZR NEDD9 CIT SMAD3 HMOX1 PLAT FERMT2 C11ORF86 STC2 OVOL1 ZC3H12C TM2D2 KDR BCL2A1 PLEKHO1 LCP1 RGS2 PARD6B LMO7 KIAA1217 APOBEC3A PTGER4 SH3TC1 SLC3A2 HBEGF MYADM NRP2 AREG PPARG SLCO4A1 KIF23 NRIP1 MTHFD2 SLC43A3 ZNF365 CXCL8 SH2D1B ARL4C CHI3L1 PTGS2 AKAP12 EGR3 BMP2 WDR72 PLAUR FGFBP1 KRT80 SLC7A5 SLC7A1 SPARCL1 EREG SOX9 DKK1 MAP2K3 UPP1 PTHLH TMEM88 IL36G SYT12 PSAT1 IL1R2 EVI2A CD19 TNFRSF12A XDH SLC7A11 HPSE FOSL1 HAS2 F3 KLHDC8A EGR4 ANGPTL4 CAV2 EHD4 ETS1 KLF4 CYR61 CTGF C11ORF96 SERPINB9 RGCC FAM107A ERRFI1 RBM3 PHLDA1 ATP2B1 LENEP ZC3H12A DDIT3 SLC25A25 COL13A1 TMEM75 EDN2 OLFM4 IL13RA2 LINC00900 FSHR C6ORF58 OR10H3 SNHG15 HERC3 STC1 TMEM213 PABPC1L2B CCRN4L DUSP5 IRS2 CSRNP1 CLCF1 CHAC1 MAFF PPRC1 SOWAHC LINC00152 CORO1C FGFBP3 ARG2 PCSK5 AGPAT9 SLCO2A1 TTC32 RND1 IL34 PIGW NNMT ASNS FAM57A SMOX RASD1 MAP3K8 TESC CTSV VNN1 BZRAP1-AS1 LINC00472 PER1 CNGA3 SLC20A1 PHACTR3 DIRAS3 TMEM133 TFPI2 MIR22HG GARS SMIM10 FEM1C EMP1 CD83 RELB CPEB2 PMAIP1 ACHE GPR115 LOC344887 S1PR1 LOC100506175 VLDLR-AS1 CBS PDK1 PPTC7 SLC9C2 PRKAG2 HRH1 DOK7 PTPRE CYP26A1 CALB1 LOC646626 LINC00925 SMOC2 SNHG7 LMOD1 PDLIM2 PRR22 HPDL KRT6B IL17D PROKR1 NRL DENND3 MIR17HG RALGDS ST7-AS1 PCDHB1 SESN2 GRAMD1B CHST2 HOTAIRM1 LOC100507165 C4ORF6 LOC100507022 TRIB1 FJX1 EGLN3 PPFIA4 C10ORF2 WFDC8 CDH12 LOC284242 TPO SNHG20 LOC100129781 ZBED2 CENPV LMCD1 FRY LPIN1 C9ORF47 CDC42EP2 IL13 OR11H12 PDLIM3 DKK4 LONRF1 RBM12 CCT6B CACNA2D3 LEMD1 IL1RAP PRSS38 LANCL2 EPHX4 INSL4 SNHG17 KIAA0040 BCAR3 FLJ30064 XYLT1 BACH2 OPALIN PHLDA2 MED14OS ZNF469 CLK1 LOC388242 ASH1L-AS1 HUS1B SERPIND1 FHL2 OSGIN1 DAPK2 LOC154761 EID3 KHDRBS2 LOC100506737 LOC100506271 ENTPD1 LOC145837 JARID2 SERPINB8 GRPEL2 MBLAC2 TRIM16L GPR6 DGKE CCAT1 LOC284561 ZNF674-AS1 VCX3A LINC00479 CHKA RTP5 FAM115C CTAG1A LIMS3 NEK6 PAG1 LOC100505592 SLC17A3 SPRYD4 MIR4435-1HG SLC25A32 PIGA GJB6 GREM2 ITLN1 SEC14L2 GJA3 LINC00312 RNF148 SRSF12 NT5DC3 PNCK SEMA7A TEKT4P2 ERBB4 LINC00313 ONECUT1 BACH1 HS3ST2 STK17A SARS perturbation; 236 Up Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 2 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. SLC5A2 IL6 GLYCTK EGR1 DDX58 TBC1D3P5 CXCL10 VIL1 OR1N2 GPT IFITM1 OR3A3 SNX31 GPA33 KLF6 IL12B IFNL3 OAS1 PTX3 OASL FRMD1 CXCL2 IFNB1 ISG15 MX1 OVOL1 CD55 IFI27 IL33 HLF APOBEC3A PARVG PLCB2 MRC1 IFI44 EPSTI1 GLDC BATF2 CXCL8 EGR3 KLF15 GADD45B SPARCL1 SOX17 FGF19 WNT5A ATF3 PTH1R SLC24A2 RSAD2 OAS3 RGS1 ZBP1 DUSP2 NPBWR1 UPK3A IFIT1 MOGAT1 IFIT3 CD84 OAS2 XAF1 CXCL3 USP18 IFIT2 CDH16 TNFAIP6 CPXM1 TEX19 EGR4 ZFP36 CDH5 IER2 IER3 FOS DUSP1 JUNB JUN IFI44L C11ORF96 TYROBP PIM3 ALOX5AP EDAR ACSM2B GEM DIRC1 RFPL1 SPANXA2-OT1 NPFFR2 DDIT3 MAB21L2 SLC5A10 OR13D1 EGR2 CCR8 NR4A3 GFAP PAEP TPT1P8 IFNL1 PIP5K1P1 HSPA6 KRTAP5-8 MLLT4-AS1 SCARA5 IL13RA2 RGR TNFAIP3 CYTH4 PLA2G4C DUSP5 CSRNP1 FOSB ARG2 ZNF385B KRTAP4-6 ARHGDIG TOMM20L MYLK2 OR10J5 C2ORF72 PNPLA5 RASD1 WAS IRAK2 SLC6A4 FETUB CXCL11 IFI6 THSD7A LOC157740 PRNT PER1 IL20 AOC4P IFNL2 LAMP3 DDX60 TNFSF13B MX2 HERC5 DDX60L CD83 PMAIP1 C8ORF4 CCDC178 SLURP1 LINC01093 PIANP KHDRBS2 CTAG1A HTR3C ANAPC2 AIM2 BHLHE22 WFDC9 KCNQ4 CFC1 ST8SIA6-AS1 LOC101929122 UPB1 KCNN1 GALNT9 AANAT NXNL1 SSTR2 HIST2H2BF GPR17 ZAN LOC100129935 FADS2 NPB HEPACAM FOXB1 SSTR3 CSH1 LOC100128239 PAPPA TCEAL7 LOC286382 FCGR1B RTN4RL2 FRG2 OR10A5 NR4A1 RESP18 ZFP42 PLA2G4F LINC00319 KRTAP13-4 LOC100506113 LINC00652 DNM1 SAMD10 DRD3 OLFM1 SERPINA9 LOC100507205 PNMA3 UGT1A8 XRCC6P5 SV2B TWIST1 ALX1 ERVH-4 INSM2 FLJ31713 SLITRK5 APBA1 MGC2889 SLITRK1 KRTAP10-10 S100Z DPP10-AS1 KIAA2022 LAMP5 OR4A15 CADM3 DEFB129 P2RX5 NR0B2 NKX6-3 TRAPPC3L ZBTB47 RCAN2 LSMEM2 IFNA6 HHIP LOC100131840 GLRA4 ANKRD30BP2 SCTR CHRNB3 TMEM255B GOLGA6L2 SARS perturbation; 264 Down Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 2 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. NOX4 OR2W1 SPINK1 SLC4A9 OR6Y1 PMEPA1 FAR2 VIT COL4A2 SIX3 FN1 AKR7A3 OR1S2 SPEM1 CSF2 KRT17 ECM1 ABCA1 MYO1G ITGAL GTSE1 SHCBP1 KIF18B LGALS1 BUB1B DLGAP5 ORC1 BCAT1 CD1A BRCA2 CEP55 SKA1 AMPH ANKLE1 TRIP13 KIF20A CPA3 NTRK1 AKAP12 CACNA2D2 CAMP COL5A2 COL1A1 MMP1 SLC24A4 TF SOST COL1A2 CXCL13 FGF5 KLK5 FGF1 MMP3 MSX2 SOX3 OR5F1 RBMY1B CXCR3 KIAA1524 ARHGEF39 STAT4 CD2 CCK HSPB3 COL3A1 MMP12 FGL1 STON1 SLC32A1 VCAN ARSI TREM1 RHCG SERPINA3 FAP LIPG PCDH10 PABPC4L LRRC17 BMP6 PLTP MYL2 SPARC PTPRB FABP5 SERPINE2 HLA-DQA1 TAGLN VIM MYLK THBS2 CECR6 LRRC39 CSPG4P5 LTA TCF23 NEXN-AS1 MYCT1 C11ORF44 PADI4 SPP2 SRPX ODF3 PCDHGB1 OLFM4 JAKMIP3 LINC00900 LOC101060157 TENM2 DEFB106B SPOCK1 FLJ13744 FILIP1L NPPB OTP OR2T5 MMP10 AMIGO2 CNN1 ANKRD1 COL7A1 COMP MAP2 MMP9 CDH6 NNMT GDPD4 ANXA10 STRA6 MMP13 C5ORF46 CCRL2 ATP6V0D2 TRPM5 BZRAP1-AS1 AFAP1L2 PMCH LAMC2 KRT16 TM6SF1 GPR115 MYL9 ITGAD ADAMTS5 FLRT2 LINC01116 FLI1 PCDHB1 OR11H12 LOC154761 MBLAC2 GJB6 SEMA7A UGT3A1 ZIM2 CYP2C8 OLFML3 LINC00311 DPEP2 NUDT10 TRBV5-4 ITGB3 LOC643733 KIAA1549L TMEM130 SRRM4 FOLR4 CSPG4 CD70 SHOX SLC6A2 MLIP SLC30A3 OR6K2 MCAM LYG2 T LOXL2 DNAJC5G LOC100131195 LYZL1 SLC39A12 PRPH HBZ IL1RL1 DCST1 SDC3 PAMR1 IGF2 APOE MAGEA8 CXCL14 DSC2 LOC101927770 LOC439938 IGHM PRY2 LAMA3 LOC100506675 KANK4 CCDC184 UNC80 COL12A1 TNFRSF10D LOC100506674 ENPP2 ECRP KRT6C KRTAP2-3 SORCS3-AS1 CTNND2 KRTAP11-1 DLL3 A1CF CT45A5 ITGB6 DOK5 ASTN1 IGFL2 ADAM19 ODF3L1 TUBB3 IVL MIATNB FAM101B ADAM12 SLC17A9 C4ORF26 GJC3 CSTL1 LINC01356 MMP2 SCGN FLJ13224 CDH13 LPPR3 KRT16P2 LINC00633 CRLF1 KRT38 RASL11B SLC26A7 TMSB15B ROR1 LOC102467073 GPR21 SLC16A10 MIR503HG SPOCD1 SPATA8-AS1 C11ORF39 DPYSL3 LOC100130700 KRT6A NGB ANGPTL5 CALD1 ANO1 CDC20B STK32A ACTG2 SLC38A3 PMCHL1 RDH12 SARS perturbation; 286 Up Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 3 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. SYNGR4 IL6 GLYCTK CCL5 EGR1 ADAMDEC1 DDX58 CXCL10 IFITM3 CTLA4 IFITM1 KLF6 IL12B IFNL3 OAS1 PTX3 UBQLNL STAT1 TREH IFITM2 EIF2AK2 OASL FRMD1 CXCL2 IFNB1 ISG15 FRMD3 NTS CXCL9 MX1 OVOL1 CD55 ARL4D SPRR3 IFI27 APOBEC3A ISG20 TOR1B PARVG BST2 SLC15A3 IFI44 ZBTB32 ADORA3 EPSTI1 SLCO4A1 BATF2 CXCL8 EGR3 STAC GADD45B EDN1 EREG ATF3 IRF4 BARX1 OR8H1 HSD11B1 RSAD2 OAS3 IDO1 IRF7 RGS1 NKG7 ZBP1 NLRC5 DUSP2 GBP5 TNFRSF9 TAP1 IFIT1 TNIP3 CLEC7A IFIT3 CD84 RTP4 OAS2 XAF1 CXCL3 GBP4 DHX58 FBXO39 IL1RN USP18 IFIT2 TGM1 HERC6 IFIH1 TNFAIP6 HMGCS2 SOCS3 TEX19 NT5C3A PARP9 PARP12 SAMD9L HSH2D IL4I1 IFI35 PARP14 SOCS1 HAS1 EGR4 UBE2L6 SP110 CSF3 TMED6 ZFP36 CYR61 IER2 IER3 FOS TEK DUSP1 PLVAP IRF9 JUNB TMEM204 JUN IFI44L C11ORF96 PIM3 ALOX5AP THEMIS2 EDAR GEM SSX2 RBM11 CREB5 FAM43B NPFFR2 MAB21L2 MAP4K1 SLC5A10 EGR2 GFAP PAEP TPT1P8 IFNL1 PIP5K1P1 TAGAP IL27 HSPA6 TRIML2 OR2B6 RGR TNFAIP3 SPDYA ACTL8 GRIK3 LINC01191 PLA2G4C NAT8 DUSP6 DUSP5 CSRNP1 MAFF FOSB PDE4B KRTAP4-6 TOMM20L PPM1K PNPLA5 FAM46A TRIM14 RASD1 WDFY4 SLC6A4 CDH9 LINC01405 CXCL11 TESC IFI6 ACTL7A PRNT GYPC IL20 IFNL2 LAMP3 DDX60 APOBEC3B TNFSF13B MX2 IFIT5 HERC5 DDX60L TMEM140 SAMD9 GBP1 CD83 KLHDC7B ETV7 GMPR CPEB2 PMAIP1 NOSTRIN PIK3AP1 C8ORF4 GPRC6A LINC01093 LOC100506175 CYP26A1 DKK4 BACH2 AIM2 WFDC9 KCNN1 AANAT SSTR2 GPR17 FADS2 SSTR3 PAPPA FCGR1B NR4A1 PLA2G4F LINC00319 LOC100506113 LINC00652 SAMD10 DRD3 OLFM1 XRCC6P5 ERVH-4 INSM2 MGC2889 DPP10-AS1 LAMP5 NKX6-3 ZBTB47 HHIP LOC100131840 GLRA4 SCTR CHRNB3 MAGEA8 A1CF ADAM8 LINC00641 PLSCR1 ERVV-1 LOC101929147 CARD11 TTTY6 PKD1L2 SPRR2E F11 SCRT2 FAM71F1 SNTG2 TCEAL2 RGS8 THEG5 LOC400707 NR1D1 GAL3ST1 TMEM95 GPR78 H1FNT UCN3 HBA2 NLRP8 DEFB105B FCER1A POM121L12 CSAG1 KRTAP9-2 P2RY8 MT1JP CHRNA2 HIST1H3J LOC285389 CLPSL2 ZNF676 PCAT7 HRASLS2 KRT24 SLED1 ADAMTS9 LOC284454 IFITM4P LINC00307 DPYS CDH19 OR52A1 C6ORF10 SARS perturbation; 214 Down Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 3 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. NOX4 SLC17A4 OR2W1 PRAP1 MME TAAR2 COL4A2 ANXA13 FN1 KRT20 POU5F2 ECM1 FMO3 FDCSP BANF1 MAPK8IP3 GLI1 NTRK1 COL5A2 GLYATL1 DMRT1 MPEG1 HPGDS TF SLC26A4 CXCL13 FGF5 ASIP DKK2 SLC45A2 PTH1R VN1R5 TAS2R9 EMR1 STAT4 XIRP2 CCK HSPB3 CSRP3 CD207 SYT10 COL3A1 MMP12 EPPIN-WFDC6 RAMP1 KL VCAN ARSI SCN3A LRRC17 CELF5 BMP6 SPARC BGN GATA2 PTPRB ADAMTS15 HLA-DQA1 CHIA TAGLN VIM LAPTM5 IL2RG MYLK CGB1 PI15 PI16 MRGPRG-AS1 RGS4 BPI FBXO40 SLC18A3 ZSCAN1 OR2A25 KIR3DL3 C21ORF128 CES5A FLJ25715 SPOCK1 STC1 MMP10 COMP MAP1B MMP9 ZNF385B CDH6 INSL5 ATP6V0D2 TXK PLAC1 PRSS1 AFAP1L2 PMCH OXTR MYL9 CSF2RB ZSCAN4 SIX3-AS1 ADAMTS5 EVI2B FLRT2 LINC01116 FLI1 LINC00925 LOC100129781 C9ORF47 INSL4 CCAT1 ONECUT1 LOC100129935 LOC100128239 OR4A15 LSMEM2 IFNA6 ITGB3 KIAA1549L TMEM130 CSPG4 SLC6A2 LOXL2 LOC100131195 PAMR1 CXCL14 KANK4 UNC80 SORCS3-AS1 ASTN1 IGFL2 FAM101B GJC3 MMP2 RASL11B ROR1 DPYSL3 STK32A CHRNA6 KIAA1755 PIWIL2 NR2E1 NKAIN4 TAS2R50 SCN2A MIR181A2HG ATP1B2 CRLF2 CARTPT KRTAP12-2 SNCB NPY6R CHRND CSMD2 LOC100128922 PSKH2 SPRY4 PGM5-AS1 ABO CLCNKA LPPR2 FAM169B NLRP14 ANKRD7 LOC643085 LOC100287869 FRMPD2 OR5A1 C15ORF27 LOC100286906 KIAA1614 ZNF503-AS1 DUSP26 CEP83-AS1 TBX18 KLK6 PCDHGB2 ADORA2A GPRC5D WFIKKN2 THSD7B AMPD1 LOC644135 NLRP4 MYO3A FLJ34521 FAM27L LOC284600 MS4A12 ST3GAL6-AS1 HAGLR OR52B2 OR52K2 VPREB1 LOC101929172 TRPM3 FAM198A KRT74 RAMP3 OR4C15 KLHL33 KLHL10 HHLA1 LOC101929550 MMP24 LINC00578 OR5P2 ISLR2 PIK3C2G OR8U1 GIPC3 HPX-2 TECTA LMAN1L RSPH1 ADCYAP1R1 CT55 SARS perturbation; 388 Up Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 4 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. IL6 GDF15 GLYCTK CCL5 EGR1 MALL TNF AADAC DDX58 OR4X2 UBE2DNL CXCL10 ACE2 IFITM3 GALR2 IFITM1 OR3A3 LAP3 KLF6 IL12B IFNL3 OAS1 PTX3 MYO7B UBQLNL STAT1 TRIM25 IFITM2 PTPRH EIF2AK2 OASL TRIM31 PGLYRP3 CXCL2 IFNB1 CD8A ISG15 CXCL9 MUC13 MX1 CLDN10 CD55 BCL2A1 ARL4D SERPING1 SPRR3 CXCL1 CXCL6 IFI27 HES1 IL33 NR4A2 S100P DUOX2 HUNK SPRR1A APOBEC3A SPRR2D PRDM1 CD300E ISG20 HESX1 SPRR1B TOR1B PARVG C1QA HBEGF TYMP BST2 PRAM1 SLC15A3 ITGAM HK3 AREG IFI44 EPSTI1 SLCO4A1 BATF2 CXCL8 LGALS9C PTGS2 EGR3 GADD45B ELANE EDN1 FGFBP1 SPDEF SPARCL1 EREG WNT2B SLC5A8 CTRC WNT10B FZD8 ATF3 MSX2 GSC OR2J2 HSD11B1 SAA1 RSAD2 OAS3 IDO1 IRF7 RGS1 ZBP1 NLRC5 DUSP2 GBP5 TNFSF14 TAP1 CCL20 EMR1 IFIT1 GPR31 TNIP3 LAG3 IL36G MOGAT1 IFIT3 CD84 RTP4 OAS2 XAF1 CXCL3 CD274 GBP4 DHX58 FBXO39 IL1RN USP18 IFIT2 TGM1 HERC6 IFIH1 TNFAIP6 MLKL STAT2 PML SOCS3 ADAR NT5C3A PARP9 PARP12 SAMD9L HSH2D ADM IL4I1 RNF213 IFI35 PARP14 FOSL1 SOCS1 EGR4 UBE2L6 ANGPTL4 WARS SP110 CSF3 SLC4A5 PIPOX MYH7 KLF4 ZFP36 CYR61 IER2 LY6E IER3 FOS RASGRP3 DUSP1 DTX3L BGN IRF9 JUNB TMEM204 JUN IFI44L C11ORF96 ALOX5AP THEMIS2 EDAR GEM IFNA10 RBM11 CGB1 RFPL1 CREB5 NPFFR2 ZC3H12A EGR2 CCR8 SPG20OS SLC22A6 PAEP EDN2 IFNL1 BEST1 TAGAP HSPA6 TRIML2 LIX1 TRIM22 TNFSF4 OR2B6 CYTIP RGR LONRF3 TNFAIP3 SPDYA HDAC9 IFNA5 LINC01191 TRPC7 HTR2B STC1 DUSP6 LIF DUSP5 CSRNP1 MIR155HG BHLHE40 MAFF ZNFX1 FOSB PNPT1 IL17C PDE4B TACR3 C15ORF48 EHMT1-IT1 SIK1 KRTAP4-6 TLR2 PPM1K TRIM21 PNPLA5 FAM46A TDRD7 TRIM14 CCRL2 RASD1 WISP2 LY6G5B SLC6A4 CD38 CXCL11 TESC CAPN14 IFI6 POU6F2 PRNT IL20 IFNL2 LAMP3 DDX60 APOBEC3B SLC25A28 ACTL9 C19ORF66 LGALS9 TNFSF13B MX2 IFIT5 HERC5 DDX60L TMEM140 SAMD9 DKFZP434I0714 GBP1 RFPL3S KLHDC7B LOC284912 ETV7 GMPR PMAIP1 C1S PIK3AP1 C8ORF4 LINC00269 LINC00599 LINC01093 KLK7 KRT6B CDC42EP2 INSL4 BACH2 LOC100505592 AIM2 WFDC9 AANAT NXNL1 SSTR2 FADS2 NR4A1 PLA2G4F LINC00319 LOC100506113 DRD3 OLFM1 SERPINA9 PNMA3 ERVH-4 INSM2 LAMP5 ZBTB47 HHIP GLRA4 ANKRD30BP2 SCTR CHRNB3 IL1RL1 FLJ13224 GPR21 KRT6A ADAM8 PLSCR1 GAL3ST1 FCER1A HRASLS2 KRT24 SLED1 LOC284454 IFITM4P C6ORF10 NCF1 FGF2 CADPS SAA2 LINC00029 LOC440792 HBE1 ASPDH APBB1IP SLC6A17 LINC00707 CD68 USP30-AS1 GPR3 PLXNB3 SCN5A SDR9C7 TNFRSF8 HTR3E LRRC3DN ABCA12 DUOXA2 RNF144A JPH2 OBP2B HRC LRRC4B UGT3A2 TMEM72 CD80 NCOA7 GZMH SPRR2C FCHSD1 SERPINB9P1 C4BPB LOC100419583 WSCD2 COX4I2 B3GNT6 CERCAM NPBWR2 ADAM21 ITGA9 KRT27 LINC01304 LPPR4 MYO16 SLC6A14 FTCDNL1 LOC100127886 FANCA GRIK5 SAA3P KRTAP9-9 CGA ETV3 OR8D1 LOC100506253 STAB1 PPM1J C1QTNF1 PTPRR SARS perturbation; 112 Down Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 4 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. NOX4 CRX ODF4 FN1 GIPC2 KCNJ13 TRPC2 CNTD1 HOXA7 PLSCR2 FMO3 SLC22A16 COL1A2 FGF1 MMP3 BRIP1 CCK HSPB3 COL3A1 MMP12 STON1 LRRC17 FMO1 TAGLN VIM FHL1 LAPTM5 MYLK NOVA1 THBS2 RGS22 LTA RGS4 FBXO40 LGI4 CCDC81 IL13RA2 LINC00900 LOC100130920 GPR182 SPOCK1 MMP10 CNN1 COMP MAP1B CDH6 AFAP1L2 TAC1 SEMA3E PMCH CD52 ADAMTS5 FLRT2 LINC01116 TPO PDLIM3 RTP5 HEPACAM LOC100507205 OR4A15 GOLGA6L2 NUDT10 TMEM130 PAMR1 APOE CXCL14 KANK4 IGFL2 ADAM19 FAM101B C4ORF26 SLC38A3 PMCHL1 FAM71F1 THEG5 DPYS PSKH2 FAM169B ZNF503-AS1 OR4C15 OR8U1 TP73 CTXN2 FAM65C ZFP57 LINC01101 ECT2L FLJ34503 TNP2 ABHD12B CHN2 B4GALNT1 C1QL2 CWH43 SPRR2G ADH6 LGSN NUMBL C1QTNF2 GPR98 LAMC3 LRFN1 LOC143286 TSPAN11 LRRC63 CATSPERD C1ORF87 TMEM214 TACR1 LOC101928327 PMFBP1 FANCD2OS SARS perturbation; 431 Up Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 5 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. IL6 GDF15 CUBN CCL5 OR2W1 APLNR EGR1 NMI TRIB3 DDX58 CXCL10 HMGB4 ACE2 IFITM3 GALR2 IFITM1 OR3A3 HLA-B THPO LAP3 IL12B IFNL3 OAS1 FCGR2A PTX3 INHBE SIX3 FASLG HIST1H4A STAT1 HLA-A IFITM2 PTPRH EIF2AK2 OASL TRIM31 CXCL2 IFNB1 ISG15 CXCL9 MUC13 ARL14 MX1 CLDN10 TLN1 CD55 PLSCR2 SERPING1 UCA1 SPRR3 IFI27 DUOX2 HUNK SERPINB2 APOBEC3A SPRR2D HIST1H2AC CD300E ISG20 SPRR1B LAIR1 TOR1B PARVG APOL1 TYMP BST2 SLC15A3 HLA-E HK3 IFI44 RENBP EPSTI1 SLCO4A1 IGHV3-48 BATF2 STAC EDN1 PLAUR WNT1 COL14A1 SPDEF EREG GRM8 CXCL13 WNT2B DCT ATF3 ASIP SOX10 FAM197Y2 HSD11B1 MIDN SAA1 PTPN22 RSAD2 SASH3 OAS3 IDO1 IRF7 CFB RGS1 ZBP1 IL18BP LCP2 DUSP2 GBP5 TNFSF14 TAP1 CD5 IFIT1 SECTM1 LAG3 XIRP2 IFIT3 CD84 RTP4 HLA-F OAS2 XAF1 CXCL3 PSMB8 CD274 GBP4 DHX58 FBXO39 IL1RN USP18 IFIT2 HERC6 IFIH1 TNFAIP6 MLKL STAT2 HMGCS2 PML TEX19 NT5C3A PARP9 PARP12 SAMD9L HSH2D IL4I1 IFI35 PARP14 EGR4 UBE2L6 ANGPTL4 HAP1 WARS SP110 CSF3 PGPEP1L AARD ZFP36 IER2 IER3 FOS RASGRP3 DUSP1 DTX3L GATA2 IRF9 JUNB PSMB9 JUN IFI44L C11ORF96 NUPR1 PPP1R14A ICAM2 IFI30 IL2RG THEMIS2 EDAR GEM RBM11 CCDC179 CREB5 NPFFR2 LOC645752 LST1 PI15 DDIT3 GABRA1 CCR8 C2ORF16 SLC22A6 PAEP EDN2 IFNL1 LCE2B BEST1 TAGAP HSPA6 TRIML2 TRIM22 EPHA8 ART3 LOC100130920 OR2B6 LOC149703 RGR TNFAIP3 SPDYA HDAC9 IFNA5 LINC01191 PLA2G4C ADAM6 HTR2B ESX1 LIF DUSP5 CSRNP1 MAFF FOSB PNPT1 PDE4B HTR1D MN1 TACR3 C15ORF48 ZNRF4 KRTAP4-6 SLC10A1 PPM1K TRIM21 PNPLA5 FAM46A TDRD7 TRIM14 CCRL2 RASD1 SLC6A4 CD38 CDH9 CXCL11 CAPN14 TXK IFI6 PSG7 THSD7A PRNT BPIFB4 IL20 GPR63 IFNL2 LAMP3 DDX60 APOBEC3B SLC25A28 C19ORF66 LGALS9 TNFSF13B MX2 IFIT5 HERC5 DDX60L TMEM140 SAMD9 GBP1 LOC400043 LOC100131662 CEACAM1 RFPL3S KLHDC7B ETV7 GMPR PMAIP1 HCG26 HCP5 OR52K3P PIK3AP1 C8ORF4 P2RY6 LINC01093 KLK7 KRT6B DKK4 BACH2 LOC284561 SLC17A3 PNCK HS3ST2 AIM2 WFDC9 KCNQ4 GPR17 LOC100129935 FADS2 PAPPA NR4A1 PLA2G4F LINC00319 DRD3 OLFM1 ERVH-4 INSM2 S100Z LAMP5 ZBTB47 HHIP LOC100131840 GLRA4 CHRNB3 LOC643733 IL1RL1 KRT6A ADAM8 PLSCR1 TTTY6 F11 NR1D1 KRTAP9-2 P2RY8 HRASLS2 KRT24 IFITM4P KRTAP12-2 ANKRD7 THSD7B AMPD1 LOC644135 FAM198A CT55 SAA2 LINC00029 APBB1IP CD68 USP30-AS1 SDR9C7 LRRC3DN DUOXA2 LRRC4B NCOA7 SPRR2C SERPINB9P1 LOC100419583 COX4I2 ADAM21 LPPR4 MYO16 SLC6A14 FANCA CGA OR8D1 PTPRR LINC01101 PYGM LOC100505474 ESPNL GOLGA6L6 LCE4A GPR50 PDCD4-AS1 PRTG WFDC11 VNN3 C8ORF12 PRODH2 GKN1 HSFX1 BEST2 HOXD13 SLCO5A1 SH3TC2 MS4A15 SRD5A3-AS1 ADRA1B GPR173 MEGF10 FLJ35700 LOC728690 SEMA3B C7ORF61 SLC13A5 CACNA1S PCDHGC4 MAS1L C1ORF127 OR1D5 IL1RAPL2 CLDN19 ALPK3 ZDHHC19 AMDHD1 CXCL12 PLXNA4 RASGRP4 HLA-H C14ORF144 CCDC116 POU4F2 FCRL2 GPR52 HPD UPK1A CASQ1 OR10G8 CACNG5 PCDHA8 LOC100507521 MBD3L1 GAGE7 CEP85 OR10A2 OR51G1 LOC729164 C10ORF25 KRT35 STAB2 GABRB2 PBOV1 HAND1 RPL3L NCR2 PCDHGC5 SCUBE3 PRKG1 PRR21 SLC35F1 GJD2 MAGEC1 AKAP7 MEIOB LOC100507140 DIO3OS NPTX2 CCSER1 FXYD7 DRP2 SARS perturbation; 69 Down Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 5 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. DDI2 FRMD1 ESM1 GLI1 AQP12B CTNNA2 LTF MSX1 MOGAT1 CKMT2 FGL1 PCDH10 C8ORF59 FBF1 DEFA3 ZNF479 LTA AMER2 HSP90AB6P TPT1P8 PCDHGB1 OLFM4 GPR182 OTP LOC100132363 SEC14L5 WFDC8 MBLAC2 XRCC6P5 FAM101B LINC01356 MIR503HG TCEAL2 THEG5 HIST1H3J DPYS LOC100287869 NLRP4 MYO3A LOC284600 OR52K2 LOC101929550 ZNF208 LOC643802 ATP8A2 TGFB3 GOLGA8EP NWD2 OR10J3 LOC100507646 GOLGA6C ILDR1 KCNA10 SBSPON SP5 LOC100132014 CDC14A NDUFAF4P1 LOC100132790 CD300LG CCDC62 NACAP1 LOC650157 C1ORF145 CR2 GS1-24F4.2 GSN-AS1 FLJ38576 CBWD6 SARS perturbation; 386 Up Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 6 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. STMN4 PPBP IL6 GDF15 TGM4 EGR1 LOX NMI DDX58 CXCL10 ACE2 IFITM3 TRIM15 IFITM1 ENTPD8 REG3A HLA-B LAP3 TBX10 KLF6 IFNL3 OAS1 TMC2 DMBT1 STAT1 HLA-A IFITM2 MFGE8 PTPRH EIF2AK2 OASL MASP2 CXCL2 IFNB1 ISG15 CXCL9 MUC13 MX1 CLDN10 CD55 ARL4D SERPING1 UCA1 SPRR3 CXCL1 IFI27 SLC4A4 S100P DUOX2 APOBEC3A SPRR2D TMPRSS11B ISG20 SPRR1B TOR1B HBEGF TYMP BST2 PRAM1 SLC15A3 HLA-E IFI44 DDIT4 EPSTI1 BATF2 AMPH CXCL8 CHI3L1 PTGS2 EGR3 MMP1 GADD45B EDN1 TF FAM20A FGFBP1 NKD1 SLC26A4 EREG CXCL13 MMP3 ATF3 PTHLH GSC OR8H1 ADAM7 TRIM49 FERD3L SCP2D1 HSD11B1 SAA1 PTPN22 RSAD2 OAS3 KLRC1 IDO1 IRF7 CFB GNG2 RGS1 LAX1 PGLYRP2 ZBP1 GBP5 TAP1 IFIT1 LAG3 PTPN7 CD207 IFIT3 CD84 RTP4 HLA-F OAS2 XAF1 CXCL3 BCL2L15 DHX58 FBXO39 C1R USP18 IFIT2 TGM1 HERC6 IFIH1 LGI3 SOCS3 ARSI NT5C3A PARP9 PARP12 SAMD9L HSH2D ADM MUC5B RNF213 IFI35 PARP14 FOSL1 UBE2L6 ANGPTL4 SP110 CSF3 MYH7 CELF5 ZFP36 CYR61 IER2 LY6E IER3 FOS RASGRP3 DUSP1 DTX3L SMAD6 IRF9 JUNB PSMB9 JUN IFI44L C11ORF96 ALOX5AP THEMIS2 SLC8A2 FLJ44715 NPFFR2 LENEP ZC3H12A C17ORF99 EGR2 CCR8 PAEP EDN2 IFNL1 BEST1 TAGAP HSPA6 PADI4 TRIM22 ODF3 CR1 LOC101060157 RGR SPDYA RXFP4 DEFB106B LOC253805 HTR2B DMBX1 DUSP6 DUSP5 CSRNP1 BHLHE40 MAFF FOSB PNPT1 MSMO1 C15ORF48 TMEM200A FAM189A1 HLA-G TLR2 PPM1K CSF3R TRIM21 PNPLA5 FAM46A TRIM14 F13A1 RASD1 WISP2 CD38 NFE2 CXCL11 CAPN14 IFI6 PRNT PER1 LINC00176 MROH2A BMP10 IFNL2 LAMP3 DDX60 C19ORF66 LGALS9 TNFSF13B MX2 IFIT5 HERC5 DDX60L TMEM140 SAMD9 GBP1 LRRC31 DEFB123 KLHDC7B ETV7 GMPR HCG26 MDK NMUR2 C1S HCP5 C8ORF4 PRTN3 TLX1 GPRC6A CUX2 LINC00269 LINC00599 P2RY6 GRIN3A LINC01093 EVI2B OR2M2 PIANP KRT6B LEMD1 PAG1 LOC100505592 GREM2 PNCK AIM2 NXNL1 LOC100129935 FADS2 FRG2 NR4A1 ZFP42 PLA2G4F LOC100506113 OLFM1 SERPINA9 ERVH-4 INSM2 S100Z HHIP ANKRD30BP2 CHRNB3 OLFML3 OR6K2 IL1RL1 ADAM12 SLC17A9 SPATA8-AS1 LOC100130700 PLSCR1 ERVV-1 SNTG2 GAL3ST1 HRASLS2 KRT24 SLED1 IFITM4P CDH19 ZNF503-AS1 KRT74 SAA2 CD68 USP30-AS1 TNFRSF8 HTR3E OBP2B TMEM72 NCOA7 SERPINB9P1 LOC100419583 B3GNT6 SLC6A14 LOC100127886 STAB1 PTPRR VNN3 SH3TC2 HLA-H CCDC116 CCSER1 KIF5A RHBDL3 KRTAP12-1 CPNE4 ADAMTS8 NRXN2 IRX6 DDN KIAA1244 NHLH2 LCMT1-AS2 LOC100506725 ADD2 ASPG SV2C CALHM1 KLHL14 SMCO3 REXO1 SMCP NFE4 MGC32805 KCNK16 POLR1A COL25A1 OR2H2 PDE1B LINC00942 HLA-J KRT76 CLCNKB S100A5 GFRA4 EXD1 PCP4 TAL1 ACP5 CATSPERB C12ORF36 OR2F1 ACY3 NEU2 OR1D2 SH2D6 HS3ST3B1 KCNH4 SLC6A13 FATE1 FAM228A LILRP2 C4B OR51E2 LINC01260 RARRES1 SFTA2 CECR1 MAST1 CA1 GABRR1 IL21R PRAMEF1 MMD2 CORIN LCN1 ELAVL2 SLC6A5 ANKRD34A ZNF454 SARS perturbation; 114 Down Genes from GEN3VA; Human airway epithelium (HAE) cells; Accession: GSE47961 ; Platform: GPL6480; Entry 6 HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. LCT CRYGD UBE2DNL VIT FRMD1 SLC39A5 NUDT12 PLSCR2 FMO3 IGKV1D-8 C3AR1 NTRK1 DMRT1 SOST IRF4 PAX6 PRKACG CD5 EVI2A NEUROG1 COL3A1 C8ORF59 FPR2 RNF113B IFNA10 ZNF479 LST1 MAB21L2 TPT1P8 MLLT4-AS1 FBXO40 OTOP3 KIR3DL3 LOC100130920 CHRM5 KCNQ1DN NPPB PABPC3 OTP GGNBP1 FTHL17 ACBD5 F10 GJD3 SPDYE1 PSG7 BPIFB4 PMCH RPL23AP32 SLURP1 ADAMTS5 LOC100505940 LMOD1 TPO PDLIM3 RTP5 HTR3C FOXB1 P2RY8 HIST1H3J TAS2R50 PGM5-AS1 LOC644135 MYO3A FLJ34521 FAM198A CADPS SDR9C7 FTCDNL1 TNP2 C1QL2 LRRC63 C1ORF127 GPR52 GOLGA6C KCNA10 NACAP1 LOC650157 GS1-24F4.2 ELFN1 MOP-1 CACNA1E MAFG-AS1 KCNH2 SNORA78 EVX1 LOC729080 ELSPBP1 C1ORF229 OSER1-AS1 ANP32A-IT1 KIAA1257 CRHR2 FAM26E PRUNE2 CSNK1A1L WDR17 FLJ35934 LOC100132147 FAM57B LOC643387 LOC142937 PFN1P2 FCAR RPS10P7 CNIH3 LPO HOXB13 IL31RA GH2 CCDC34 FFAR4 LOC100131262 C5ORF58 SARS Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CD209 IFNAR1 IFNA1 FAM71D VCAM1 ANPEP TMPRSS2 UBD IRF3 CXCL5 DDX58 TBK1 YWHAZ IL1A CXCL10 IFITM3 ANXA3 IFITM1 FCER2 GOLGA2 IFNG IFNL3 NFKB1 OAS1 FCGR2A REG4 CTSD STAT1 TRIM25 TRAF3 B2M CLEC4G EIF2AK2 IL12RB1 TMEM173 NLRX1 ITM2A OASL ALDOB CLEC4M CXCL2 IFNB1 ISG15 ICAM3 TMPRSS13 CXCL9 MX1 CPT1A BCL2A1 HOXC6 SERPING1 CXCL6 ITGA2 RPLP2 SERPINB5 SERPINB2 RPS18 CCL8 ISG20 MT-CO2 IL4R LGALS3BP RNASEL ITGB5 BST2 SLC11A1 IFI44 IGFBP2 IRF5 MAFB BIRC5 C1QB EPSTI1 ITGA1 GAPDH MMP19 PSMB2 MKI67 CD163L1 PTGDR MAVS MMP1 ACTB EDN1 FCN1 RSAD2 OAS3 IRF7 CCL1 CCL20 CLEC5A IL2RB IFIT1 KNG1 LY86 CLEC7A FCGR2B IFIT3 RTP4 TLR7 HLA-F OAS2 PSMB8 DHX58 IL1R2 USP18 IFIT2 IL2RA IFI16 CLEC4E IFIH1 STAT2 IFNA4 INHBA IFI35 SOCS1 SAMHD1 UBE2L6 TLR3 PLAU CSF3 IRF2 PSME2 LY6E IGFBP4 IRF1 ATP6V0E1 IRF9 PSMB9 DRAM1 RPLP0 PPIB TAGLN IFI44L DDX3X PSMA6 CREB5 IFNL1 TRIM22 IL22RA2 RNASEH2A MSLN IL15RA TRIM56 NID1 CXCL11 IFI6 IFNL2 PLAGL1 DDX60 MX2 IFIT5 HERC5 GBP1 IGFBP1 CD83 ETS2 CX3CL1 C1S SOD2 IFNA2 IFNA14 IL7 SRGN AIM2 ATP1B2 TNFRSF8 STAB1 TLR8 TBX15 AIMP1 PUM1 SF3B3 ANGPT2 GFI1B IL10RB RNF125 IFNGR1 HSPA1B CCL22 GNA12 CDH2 IFNA8 CFHR1 CD40LG PRDX2 SIAH1 IFNA17 FSD1 RHOT1 RNF135 MTSS1 ITGA6 OTUB1 PGK1 IRAK1 TNFRSF25 PSMC4 TNFSF9 IFNA7 SARS 8 Literature-Associated Kinases Genes from Geneshot GeneRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). MAPK3 TBK1 MAPK14 PKLR EIF2AK2 PI4KB EGFR MAPK1 SARS 5 Predicted Kinases Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). TBK1 EIF2AK2 RNASEL PGK1 IRAK1 SARS 1 Literature-Associated GPCR Gene from Geneshot GeneRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). BDKRB1 SARS 1 Predicted GPCR Gene from Geneshot GeneRIF via AutoRIF Co-Occurrence Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). PTGDR SARS Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). TICAM2 F2RL1 JAK1 IL2 CD209 IFNAR1 IL6 MAPK3 SFTPD IFNA1 HSPA5 SLC6A18 CCL2 CCL5 VCAM1 TMPRSS2 TNF KPNB1 IRF3 CXCL5 DDX58 TBK1 IL1A DDX21 CXCL10 ACE2 TLR4 PF4 FCER2 KLK3 SLC6A19 ST14 THPO ETV4 IFNG ERG IFNL3 NFKB1 IL4 OAS1 FCGR2A ADAM17 STAT1 B2M TMPRSS11D CLEC4G EIF2AK2 TMEM173 RAE1 APOBEC3G OASL MASP2 CLEC4M IFNB1 ETV5 ISG15 MBL2 ICAM3 SPI1 CXCL9 IL10 STAT6 MX1 MYD88 MAPK1 TNFSF10 IL33 CCL8 KHSRP RNASEL CD81 TYK2 HLA-E SLC11A1 C3AR1 CTSB AREG ADAM15 IRF5 ICAM5 CXCL8 CCL4 MYC MAVS AXL MEF2C CXCL13 ELF4 IFNW1 FCN1 OAS3 IDO1 IRF7 ZBP1 TNFRSF9 CCL1 CCL20 IFIT1 CCR5 CCL13 S100A9 IFIT3 TLR7 OAS2 C3 PSMB8 CCR1 IFIT2 IFI16 IFIH1 STAT2 SOCS3 CCL11 IFNA4 SOCS1 SAMHD1 C5AR1 TLR3 ETS1 IRF1 ICAM1 IRF9 PPIB DDX3X ICAM2 CALR RAB11A MKNK2 CD9 CCL26 IFNL1 TLR9 LMAN1 MMP9 IL1R1 TLR2 ETV6 TRIM21 TAPBPL USP25 AZI2 CXCL11 IFI6 CRABP2 IFNL2 AMFR MX2 GBP1 SIKE1 YY1 PMAIP1 TICAM1 CX3CL1 RHBDF2 IFNA2 CDKN1B ADAM10 ADAM19 ADAM8 CXCL12 C4B TLR8 IFNGR1 IFNA17 ZDHHC1 HOXA10 SKP2 PTPN1 CGAS C4A FCN2 MOG SEMA4D CCL12 CD209B CCL3 DHX36 GATA1 RAD21 MASP1 COLEC11 PLAGL2 ORMDL3 PRKCD TYRO3 PPP3R2 RUBCN IFNAR2 BDKRB2 TRIM32 IKBKE CD209A PLA2G6 CCL7 HC TRAF6 KPNA1 FCN3 SARM1 SARS 12 Predicted Kinases Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). JAK1 MAPK3 TBK1 EIF2AK2 MAPK1 RNASEL TYK2 AXL MKNK2 PRKCD TYRO3 IKBKE SARS 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via GeneRIF Co-Occurrence Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). MKNK2 SARS 6 Predicted GPCRs Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). F2RL1 C3AR1 CCR5 CCR1 C5AR1 BDKRB2 SARS Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). SYVN1 UBE2D2 PSMD8 SNX1 EXOSC3 SHQ1 UBE2K SWI5 PPT1 GABARAPL2 RAB8A ALG5 PSMD4 NUTF2 TDP2 PTH SIL1 ARF6 RAB1A UAP1 GFER PGM2 UFC1 ACO1 ZNF410 URM1 UNC50 COQ5 ADPRH SDHD SNX3 VPS25 AR PSMD6 PREB PSENEN SDHB SYF2 PFDN6 PSMD3 SLC39A1 TRMT112 ARF1 TRAPPC2 VPS35 VPS26A SUB1 SUPT5H RAB5A PIN4 COX14 SLA UBE2M POLR2G PRKAG1 TXNDC17 GEMIN2 PSMD13 TAF12 UBE2N TTC1 COPS5 PPP1R7 FLOT2 TPRKB UBE4A TRAPPC3 POLR2J AHSA1 FAM96A PSMD14 VAMP7 SNRPA UBA3 USO1 SF3A3 RRAGC ZMPSTE24 TRIM21 WAS HSCB NUDT1 RALBP1 TAF10 ACTR3 ADH6 COPS4 ZPR1 TERF2IP POP4 POLR2C TRG POT1 FBXL5 ACOT8 ORC2 NUBP1 PEF1 VPS45 WDR82 ALG1 SDHA TIMM23 VTA1 HIKESHI UFD1 GLRX3 STN1 GOSR2 TWF1 STX5 PSMD7 TBCE TRAPPC1 SRP68 GET4 COQ6 ANAPC11 SYS1 PFDN1 COPZ1 PSMD9 PHF5A PSMD11 SAMM50 AASDHPPT TRMT10A THUMPD1 SNRPD3 TADA3 EXOSC10 COQ9 TADA2A POLR2H RAB35 FTSJ1 SCFD1 PSMG2 SNF8 VPS29 YEATS4 RNF113A EXOC1 ERVK21 RER1 SEC13 SMN1 TIMM21 OLA1 OGG1 SUGT1 TRAPPC4 YKT6 SURF4 UBL4A SUPT4H1 NXT1 PLAA EXOSC1 ACTR1A GATB ANAPC10 COPS3 ZNF655 UBE2V2 VPS36 QRSL1 PEX2 TXNL4A PFDN4 SEM1 PPA2 SLC31A1 RTCA GTF2H5 TIPRL TRNT1 ACP1 SUPT20H PET100 RPE RANGRF COX11 SFR1 TUT1 TEN1 TSG101 USB1 SENP3 TRAPPC5 SSU72 PEX3 PPP1R8 OGFOD1 RIT1 SACM1L RMDN1 GLE1 HBS1L EXOSC7 SARS 1 Predicted Kinase Gene from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). PRKAG1 SARS Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CD209 IFNAR1 UBE2D2 FAM71D SEC14L1 DDX10 GHITM IRF3 DDX58 TBK1 UBC CXCL10 UBE2K ACE2 IFITM3 CXCL16 ANXA3 IFITM1 FCER2 SLC6A19 OAS1 REG4 STAT1 TRAF3 IFITM2 CLEC4G EIF2AK2 OASL CLEC4M IFNB1 TBKBP1 ISG15 MBL2 ICAM3 MX1 RWDD3 CXCL6 CCL8 COX7C ISG20 KHSRP UNC93B1 RNASEL CD81 BST2 TYK2 C3AR1 IFI44 IRF5 MAFB EPSTI1 C2 PSMB2 TRAT1 MAVS TRIM16 IFNK DCT IRF8 IFNA13 PSMA3 RNF26 FCN1 RSAD2 OAS3 CLEC4C IRF7 CLEC5A NUSAP1 IFIT1 CLEC4A CLEC7A FCGR2B IL36G CD207 IFIT3 RTP4 TLR7 OAS2 SIGLEC1 XAF1 CLEC6A PSMB8 DHX58 USP18 IFIT2 IFI16 CLEC4E IFIH1 STAT2 GBP2 IFNA4 INHBA IFI35 UBE2L6 TLR3 UBA7 IRF2 PSME1 PSME2 LY6E IRF1 IRF9 TSPAN7 DRAM1 RPLP0 PPIB IFI44L TAPBP DDX3X RPL15 IL3RA ICAM2 CREB5 IFNL1 TRIM22 UBE2S PRDX4 UBE2N UBA3 LRP11 MXI1 IL15RA MARS2 TRIM56 TRIM5 CXCL11 IFI6 IL32 IFNL2 LAMP3 DDX60 RNF19B C19ORF66 MX2 IFIT5 HERC5 GBP1 TICAM1 C1S IFNA14 CD53 TRIM16L PLSCR1 SPRR2E ATP1B2 STAB1 HOXB13 TLR8 TBX15 GFI1B RNF125 HSPA1B GNA12 IFNA8 IFNA17 RNF135 PSMC4 IFNA7 ZDHHC1 HOXA10 CGAS FCN2 MASP1 COLEC11 IFNAR2 FCN3 TENT5A RANBP2 COLEC10 LYL1 UBE2J1 CD93 UBA2 RGPD2 C8B ITIH4 TANK IFNLR1 KRBOX1 MYCN CLECL1 RNF5 TXLNA PIAS3 TMED7-TICAM2 IFNA21 TRIM17 UBE2H CSTF3 PPIE UBE2B IDI1 C3ORF14 RIOK3 OLFML1 APOBEC3F ZDHHC11 CAMSAP1 THAP12 SARS 5 Predicted Kinases Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). TBK1 EIF2AK2 RNASEL TYK2 RIOK3 SARS 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). RIOK3 SARS 1 Predicted GPCR Gene from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). C3AR1 SARS Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). GMIP NMI LILRB2 ARRB2 LYN HLA-B LAP3 OAS1 HLA-C STAT1 HLA-A FMNL1 AGTRAP FERMT3 LILRB1 SPI1 STAT6 MX1 MYD88 RILP STXBP2 MGAT1 LCP1 NINJ1 IGSF6 APOBEC3A ISG20 UNC93B1 ARHGAP30 ITGB2 LSP1 MYO1G PARP10 PARVG VASP RPS6KA1 LRRC25 CD37 TYMP CYBA SHKBP1 BST2 UNC13D PLEKHO2 ADGRE5 SLC15A3 HLA-E EMP3 IRF5 EPSTI1 BATF2 CD300C ELF4 BCL3 ARHGAP27 HCLS1 CD48 SASH3 OAS3 IL10RA IRF7 PSTPIP1 DENND1C AOAH LCP2 PYCARD TAP1 PIK3R5 CLEC4A SECTM1 RAC2 CORO1A VAV1 FCGR2B FCER1G RTP4 TLR7 OAS2 PSMB8 CCR1 DHX58 TREX1 USP18 CMPK2 OSCAR PTAFR IFIH1 MLKL PML TCIRG1 NFKBIE GBP2 GLIPR2 PARP9 PARP12 HSH2D CASP4 NOD2 IFI35 TRAFD1 UBE2L6 UBA7 SP110 IRF2 IRF1 PSMB10 RHOG SIPA1 DTX3L IRF9 PSMB9 LITAF OAZ1 TYROBP TALDO1 LIMD2 LAPTM5 HCK THEMIS2 NCF4 EFHD2 LST1 SIGLEC7 RGS14 SIGLEC9 CYTH4 TNFRSF14 RIPK3 TAP2 CSK CASP1 IL15RA TRIM21 GSDMD SELL TRIM14 WAS SNX20 RNF19B C19ORF66 LGALS9 MX2 GBP1 ETV7 ARPC1B NAPA APOL3 MOB3C MSRB1 CNPY3 ARPC4 GPSM3 PTPN6 CD53 PLEK ADAM8 NCF1 IL10RB PRKCD FUT7 PILRA NCF1C ADGRE1 APOBR NAGK TBXAS1 SIGLEC5 C17ORF62 LILRB3 HPS1 CD300A TNIP1 XXBAC-BPG246D15.9 SH3BP1 RIN3 LILRA6 LILRA5 GPR132 ARHGAP9 FGR IKBKG STX11 SCO2 NADK NCF2 C19ORF38 GK NCF1B FCGR3A SIGLEC14 RGS19 OSTF1 PIK3CD AQP9 ARHGAP45 DOK3 HLX FGD3 TRADD CARD16 SARS 10 Predicted Kinases Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). LYN RPS6KA1 MLKL HCK RIPK3 CSK PRKCD FGR IKBKG PIK3CD SARS 5 Predicted GPCRs Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). ADGRE5 CCR1 PTAFR ADGRE1 GPR132 SARS 1 Predicted Dark GPCR Gene from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). ADGRE1 SARS 460 Literature-Associated Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CASP6 JAK1 IL2 CD209 IFNAR1 TRIM55 IL1B BCL2L1 SLC5A2 IL6 ENDOU SARS2 DPP4 FKBP1A EIF3F PRKCZ FGL2 POU5F1 CCL2 CD34 ANPEP STAT3 EGR1 TMPRSS2 CTSL GHITM SQSTM1 VDR VCP YWHAQ LOX TNF KPNB1 IRF3 KPNA2 DDX5 TRIB3 TOM1L2 HIST1H1C DDX58 TSPO TBK1 RCHY1 MPP5 COPB1 CXCL10 CCND3 ACE2 IFITM3 TLR4 IL17RD CXCL16 CTLA4 PLA2G2D ANXA3 AHSG ATF6 IFITM1 PF4 AGTR2 DDX1 RASA3 FCER2 ANXA2 GABARAPL2 HLA-B FURIN EPS15 SARS RUNX1 HSPB1 JAK2 BAG3 KLF6 XIAP IFNG VIT SMAD3 CTNNB1 IL4 HOXA9 SERPINE1 PHB2 OAS1 AGPS COPB2 ATM SIX3 GNGT2 ADAM17 RELA TMPRSS11A ACE STAT1 TRIM25 TRAF3 HLA-A IFITM2 VARS ABCG2 CLEC4G ERBB2 DEDD IL12RB1 WARS2 RARS APOBEC3G EIF4E PTH NEDD8 BRD4 MASP2 CLEC4M CXCL2 PPIG TGFB1 ISG15 SRC EGFR PPIH APP RPH3A FKBP1B ICAM3 PPIA CXCL9 USP7 CASP3 LRRC2 PLP2 EDEM1 IL10 CDK2 STAT6 MX1 MYD88 ESM1 PSMB1 SRR ADH5 KDR NPY CPT1A ADK ATF5 IKBKB CAV1 ALB SGTA CXCL1 CFTR ARL3 SIX1 PATJ PBX1 FOXP2 PITX1 GADD45A SLPI CEACAM5 CCND1 STIM1 AKT1 ALOX5 BST2 TYK2 SMAD7 RARA PLK1 TOP2A CEBPA CTSB LPL CDK5 FLT3 MSR1 CDC25A CDK1 C1QB CES1 CD163 GAPDH CCR2 MKI67 CCR3 ABCB1 CXCL8 RUNX3 PTGS2 EGR3 IGFBP3 CDKN1A MYC BMP2 MAVS ABCC2 AXL ABCG1 FGFR1 BDNF MITF WNT1 INS MTOR SLC7A1 SRY SOX17 FGF8 FGF7 SOX7 LAMP1 ATF3 GABARAPL1 SOX11 OTX1 CD63 CASR PAX6 CBX4 CXCR3 CD69 IDO1 IRF7 CD5 CD27 GPR84 LHX2 LCK GP2 TOX IFIT1 CCR5 CD2 GPR55 PON1 TLR7 CD86 XAF1 CCR1 GRIA1 CD19 DHFR IFIH1 STAT2 SOCS3 NAMPT NFIL3 SLC7A11 SELP ARG1 TLR3 PCBP2 FOS MAP1LC3B CRYAB SIPA1 ICAM1 NFKBIA GSTP1 CLDN5 VEGFA PDE5A PPIB PPP1CA ICAM2 ATF4 ARF1 VWF GNS SMAD4 PGLS DDIT3 AOC3 MBP NOS2 PPP1R15A GP6 CR1 BMP5 ESRRG RXFP4 TLR9 IKZF1 TG AICDA IFITM5 CYP4F3 AQP4 NGF IL11 FOSB HMGB1 UCHL3 HDAC1 ATG5 TUFM NARS CDK4 CDC25B MALT1 PDE4B HAMP ID1 MMP9 BCHE CDCA7 ABL2 NNMT PLG ASNS TLR2 CASP1 CD40 GPR18 INSL5 TFRC CD38 CXCL11 AARS IARS TAC1 SMG1 MX2 GBP1 TOP1 MECP2 IGF1R CETP BTK TRPV1 CD83 CEACAM1 RELB PMAIP1 HLA-DRA CCR7 CASP8 HNRNPA1 ITK ADAM10 DYRK1A CD44 GPR17 SLC6A2 SPRY4 NCF1 CD68 HRC CXCL12 KCNH2 TLR8 AIMP1 PUM1 CDH2 PGK1 PTPN1 TRAF6 TANK PROP1 NANOS1 TIRAP MTR ITCH GDF5 CRP PAX2 IGF1 PRL UGT2B7 CTCF ARL2 SHBG HHEX CLPX CDK9 NTSR2 BCL2L14 UCHL1 CAMK2D LARS LIPE ALK USP33 SP8 NPC1 AGO2 BCR DARS USP14 RET KDM1A CASP5 EIF2AK4 DNM1L CASP9 NPS NAAA HBA1 KARS PHOX2B CHAT CARS SLC6A3 ARF5 CREB1 DPP8 CPB2 DOT1L MDM4 KIT ASIC4 DICER1 SOX5 CYP17A1 NKX2-2 PRMT1 DPP9 CLCN3 NFATC1 PITX3 NKX2-1 TNKS BACE1 HPRT1 FAIM CYP2C9 PGF MAP4K4 POMC MRAS TBP EEA1 FOXJ1 TRPA1 TBX2 KIR2DL3 CDK6 TNFSF11 PAX1 GNAQ RECK EGLN1 BSG SPEN CXCR4 TERT ROS1 WIPI2 PARP1 YARS MLLT3 HDAC8 SPRY1 FAAH HFE XBP1 SMG6 TFEB CLPP PPARGC1A SARS 40 Literature-Associated Kinases Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). JAK1 PRKCZ TRIB3 TBK1 JAK2 ATM ERBB2 SRC EGFR CDK2 KDR ADK IKBKB AKT1 TYK2 PLK1 CDK5 FLT3 CDK1 AXL FGFR1 MTOR LCK CDK4 ABL2 SMG1 IGF1R BTK ITK DYRK1A PGK1 CDK9 CAMK2D ALK RET EIF2AK4 KIT MAP4K4 CDK6 ROS1 SARS 15 Literature-Associated GPCRs Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). AGTR2 CCR2 CCR3 CASR CXCR3 GPR84 CCR5 GPR55 CCR1 RXFP4 GPR18 CCR7 GPR17 NTSR2 CXCR4 SARS 2 Literature-Associated Dark GPCRs Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). RXFP4 GPR18 SARS 7 Literature-Associated Ion Channels Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CFTR GRIA1 TRPV1 KCNH2 ASIC4 CLCN3 TRPA1 SARS 1 Literature-Associated Dark Ion Channel Gene from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). ASIC4 SARS Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CD209 IFNAR1 FKBP1A IFNA1 PRKCZ VCAM1 ANPEP SEC14L1 GHITM SQSTM1 IRF3 TOM1L2 HIST1H1C DDX58 TBK1 YWHAZ MME CXCL10 ACE2 IFITM3 ANXA3 YWHAB IFITM1 NBR1 RASA3 FCER2 KLK3 OAS1 GNGT2 RELA STAT1 TRIM25 TRAF3 IFITM2 B2M EIF2AK2 IL12RB1 TMEM173 OASL CLEC4M CXCL2 PPIG IFNB1 CD8A ISG15 PPIH RPH3A FKBP1B ICAM3 TMPRSS13 CXCL9 LRRC2 PLP2 MX1 TRIM23 MT2A RPL9 CCL8 ISG20 UNC93B1 DDX41 LGALS3BP CD81 BST2 TYK2 CAPG IFI44 RNASE2 ADAP2 IRF5 EPSTI1 MMP19 CPA3 MAVS EDN1 LTF AGRN TPD52L1 MMP8 F2R RSAD2 OAS3 CLEC4C IRF7 FCGR1A IFIT1 STAT4 LY86 TBX21 IFIT3 RTP4 TLR7 OAS2 DHX58 USP18 IFIT2 IL2RA IFI16 HERC6 IFIH1 TNFAIP6 STAT2 MCOLN2 SERPINA3 INHBA IFI35 SOCS1 SAMHD1 UBE2L6 TLR3 PLAU IRF2 FTH1 PSME2 LY6E IGFBP4 IRF1 SIPA1 MYL12A DTX3L NFKBIA ATP6V0E1 IRF9 PPIB IFI44L DYNLT3 PSMA6 PSKH1 GNS MARCKSL1 TRAF1 IFNL1 SPON2 IFITM5 PARK7 RFC4 ANKRD1 TRIM56 TFRC CXCL11 IFI6 IFNL2 DDX60 MX2 IFIT5 HERC5 SAMD9 GBP1 NFE2L3 TICAM1 APOL3 IFNA2 TRIM26 EIF4A1 GAS1 TRIB1 ADAMTS9 SPRY4 ADORA2A STAB1 CXCL12 TLR8 TBX15 AIMP1 PUM1 RNF125 IFNGR1 HSPA1B GNA12 CD40LG RNF135 PGK1 IRAK1 TRIM32 TRAF6 TANK TNIP1 USP33 HBA1 MRAS TERT SMG6 SIM2 TNFRSF1B GNAS TRIM63 PIAS1 TIMP3 POSTN CA12 CELSR2 CTSF F2RL2 AKR1D1 OTUB2 FAM111A RNF11 TAX1BP1 NFATC2 B4GALNT4 SARS 1 Predicted Dark Kinase Gene from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). PSKH1 SARS 4 Predicted GPCRs Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). F2R ADORA2A CELSR2 F2RL2 SARS 1 Predicted Ion Channel Gene from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). MCOLN2 SARS Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). TICAM2 CD209 MAPK3 DPP4 IFNA1 CCL5 CD34 ANPEP STAT3 TMPRSS2 SQSTM1 MAP1LC3A IRF3 DDX58 TBK1 MME CXCL10 IFITM3 TLR4 RNPEP IFITM1 TMBIM1 YWHAE FCER2 KLK3 SLC6A19 NDRG1 ETV1 SARS IFNG IFNL3 NFKB1 IL4 MAPK14 USP2 OAS1 CTSD ADAM17 RELA STAT1 TRIM25 TRAF3 IFITM2 CSNK2A2 TMPRSS11D CLEC4G EIF2AK2 TMEM173 WARS2 GNB1 CLEC4M AGTRAP IFNB1 ISG15 SPI1 CXCL9 LNPEP STAT6 MX1 RAB5C MAPK1 ERC1 RPS6KB1 TMBIM4 DEDD2 IFI27 YAP1 HIST1H1E HIST1H1D TC2N TAB2 BAX TMBIM6 GRINA AKT1 GNB2 CD81 EDEM2 CTSB AURKB CENPW RNASE3 CXCL8 CDKN1A RUNX2 MAVS AXL MTOR CXCL13 IRF8 CTSC CREBBP TNFRSF1A CXCR3 RSAD2 IDO1 IRF7 CCL20 FCGR1A IFIT1 FCGR2B RYR2 IFIT3 XAF1 USP18 IFIT2 IFI16 SNCA STAT2 SOCS3 TNFRSF12A FOSL1 SOCS1 C5AR1 TLR3 UBA7 ETS1 IRF1 DUSP1 IRF9 LUC7L3 DDX3X CD9 IFNL1 PRPF3 PPP3CA FKBP4 ZNF512 HAMP HIST1H1A PCSK1 CSK CD40 TRIM21 CXCL11 IFI6 IFNL2 MX2 HERC5 GBP1 IGF1R SIKE1 YY1 CHUK PNISR ETS2 TICAM1 CSTB IFNA2 OPTN TRIM26 ADAM10 FLI1 NCF1 TNFRSF8 CXCL12 AIMP1 IFNGR1 CGAS IKBKE TSG101 TANK RIOK3 IKBKG DOK3 DARS KDM1A DPP8 BACE1 TRIM63 PIAS1 PCSK2 GNRH1 IFNGR2 SYK RYR1 FAIM2 MMP14 PELI1 NFKB2 SC5D ARRB1 CALCR EGF HIST1H1B QARS STARD7 NEDD4 ATP2A2 NR2C2 MFSD2B TFR2 PAX5 RAB4B MAP3K7 TGFBRAP1 MRPS12 GTF3C3 TRIM54 SARS 2 Predicted Dark Kinases Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CSNK2A2 RIOK3 SARS 3 Predicted GPCRs Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CXCR3 C5AR1 CALCR SARS 2 Predicted Ion Channels Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). RYR2 RYR1 SARS Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). RAB2A RAD23B UBE2D2 PSMD8 SNX1 GOLGA7 PPT1 RNPEP STOML2 GRPEL1 RAB8A RAB14 ERP44 TRIM25 SAP18 TDP2 PMPCB PEPD SIL1 ARF6 RAB1A RAB5C PGM2 UFC1 XPA TBCB VPS37C GRK2 URM1 TMED9 TOLLIP SCAMP2 SEC11A ADPRH SEC23B HCCS FH SNAPIN SNX3 VPS25 ALDH9A1 PSMB2 TMOD3 PSMD6 FIBP RAP1A AIDA PSENEN AKR1A1 SMDT1 SDHB GLTP RAP1B FDX1 TALDO1 RAB11A UBE2V1 GYG1 PRPSAP1 VTI1B VPS35 VPS26A WASF2 RAB5A GLOD4 UBE2L3 WBP2 PRKAG1 TXNDC17 PSMD13 TMX1 UBE2N TTC1 PPP1R7 FLOT2 UCHL3 PSMC1 TRAPPC3 FAM96A PTDSS1 SYPL1 AP3S1 UBA3 USO1 GOT2 SRI RRAGC ZMPSTE24 PTS CSK SPPL2A VPS4B RALB RALBP1 COPG1 SNX12 RSU1 ACTR2 ACTR3 AIMP1 COPS4 NUBP1 PEF1 VPS45 SDHA VTA1 GLRX3 GOSR2 TWF1 PSMD7 SRP68 PFDN1 COPZ1 EXOSC10 RAB35 SNF8 VPS29 ERVK21 SEC13 OLA1 SUGT1 TRAPPC4 YKT6 SURF4 PLAA ACTR1A GATB COPS3 QRSL1 RTCA GTF2H5 RPE TEN1 TSG101 GLE1 HBS1L TXNDC5 AP3M1 STX7 ARCN1 TMEM167A HARS TSNAX RTCB ESD PSMD5 ERP29 HSFX3 PLEKHB2 GNPNAT1 GBA NUDT5 UBAP1 SELENOF PRKAB1 FAF2 TMEM11 TBC1D20 API5 RPL9P8 UXS1 SETD3 GRSF1 STX8 STXBP3 SPRYD3 TSN RABIF SLC9A9AS1 CPPED1 TXNL1 TXN2 GNAI3 VDAC1P5 ADPGK AP1B1 USP5 STX4 YIPF1 PPP5C UGP2 SF3B6 HMOX2 XPNPEP1 TOM1 SH3GLB1 SEC22B RAB5B TBRG1 STARD3NL APMAP SPG21 PITPNA COPG2 PLBD2 ANXA7 PPP4C SNX6 EXOC2 PLPBP SARS 4 Predicted Kinases Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). GRK2 PRKAG1 CSK PRKAB1 SARS Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). PPIL3 CD209 TARS2 IFNAR1 FKBP1A PRKCZ FKBP10 SEC14L1 GHITM SQSTM1 IRF3 TOM1L2 DDX58 TBK1 IFITM3 ANXA3 IFITM1 NBR1 OAS1 GNGT2 STAT1 TRAF3 IFITM2 NARS2 EIF2AK2 IL12RB1 TMEM173 OASL CLEC4M IFNB1 ISG15 PPIH RPH3A FKBP1B ICAM3 PPIA LRRC2 PLP2 MX1 FARS2 YARS2 TRIM23 TENT5C CCDC7 ISG20 KHSRP UNC93B1 ARF3 RNASEL FKBP8 CD81 BST2 TOLLIP CAPG FKBP9 IFI44 ADAP2 IRF5 EPSTI1 TRAT1 MARS MAVS B3GNT3 IFNK IRF8 IFNA13 RSAD2 OAS3 CLEC4C IRF7 TAP1 IFIT1 CLEC4A FCGR2B RYR2 IFIT3 RTP4 OAS2 XAF1 CCR1 BCL2L15 DHX58 USP18 IFIT2 IFI16 HERC6 IFIH1 STAT2 GBP2 MCOLN2 PARP12 IFNA4 IFI35 SOCS1 TRAFD1 UBE2L6 TLR3 UBA7 IRF2 PSME1 PSME2 LY6E IRF1 SIPA1 DTX3L IRF9 PPIB IFI44L ZMYND11 ICAM2 PSKH1 CYP2S1 PPIC IFNL1 TRIM22 IFITM5 RCN2 RFC4 IL17C NARS MXI1 FKBP4 OTX2 MARS2 TRIM56 TRIM5 GPR183 CXCL11 AARS IFI6 IFNL2 DDX60 RNF19B C19ORF66 MX2 IFIT5 HERC5 SAMD9 GBP1 SCRN1 IL17B TICAM1 TRIM26 RAP2B SPRY4 STAB1 TLR8 TBX15 RNF125 IFNGR1 HSPA1B GNA12 IFNA17 RNF135 PGK1 CGAS TRAF6 COPZ1 SURF4 TANK IFNLR1 TMED7-TICAM2 MRAS YARS SMG6 TRIM63 CELSR2 F2RL2 RNF11 TAX1BP1 B4GALNT4 IFNGR2 QARS HARS EIF3D FKBP11 NDUFB1 ATG9A FKBP2 IFITM10 PARS2 CARS2 COPA FARSB RAB22A TRAPPC10 HAUS8 ZDHHC20 RARS2 TNFAIP8 FKBP3 FKBP1C SEPHS1 PPID TARSL2 ZIK1 LARS2 ACOD1 FKBP14 ZBTB38 SARS 1 Predicted Dark Kinase Gene from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). PSKH1 SARS 4 Predicted GPCRs Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CCR1 GPR183 CELSR2 F2RL2 SARS 2 Predicted Ion Channels Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). RYR2 MCOLN2 SARS Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). FCGRT MVP ADAMDEC1 NMI LMAN2 TSPO LILRB2 SLC7A7 IFITM3 HLA-B LAP3 NLRP6 RAB8A RBCK1 OAS1 HLA-DRB1 HLA-C STAT1 TRIM25 HLA-A OASL AGTRAP LILRB1 NUB1 MX1 MYD88 RILP MGAT1 LCP1 TNFSF10 NINJ1 APOBEC3A ISG20 UNC93B1 ARID5A MYO1G PARP10 TRPV2 RPS6KA1 TYMP CYBA SHKBP1 BST2 PLEKHO2 SLC15A3 APOL2 HLA-E EMP3 FBXO6 SYNGR2 SCAMP2 TWF2 RAB20 GLRX IFI44 ADPRH IRF5 CTSZ EPSTI1 GSTO1 BATF2 MSC BATF ELF4 BCL3 CD48 RSAD2 SASH3 OAS3 IRF7 SLAMF7 TAP1 SECTM1 RAC2 SLAMF1 CCR5 IFIT3 RTP4 OAS2 SIGLEC1 PSMB8 CD274 CCR1 DHX58 IL1RN TREX1 USP18 CMPK2 IFI16 OSCAR IFIH1 STAT2 PML TCIRG1 NFKBIE GBP2 MCOLN2 PARP9 PARP12 IL4I1 IFI35 TRAFD1 UBE2L6 WARS SP110 IRF2 PSME1 PSME2 SHISA5 LY6E PSMB10 RHOG CAPZB DTX3L ATP6V0E1 IRF9 PSMB9 ARPC3 LITAF OAZ1 IFI30 TALDO1 LAPTM5 EHD1 EFHD2 TRAF1 TNFRSF14 ZNFX1 S100A11 ATP6V0D1 PPP1R18 ETHE1 RIPK3 FUOM TAP2 CASP1 IL15RA CD40 TRIM21 GSDMD TDRD7 TRIM14 IFI6 LY96 RNF19B C19ORF66 LGALS9 MX2 GBP1 RALB RELB ETV7 TICAM1 ARPC1B NAPA APOL3 MOB3C CLIC1 ARPC4 RNH1 CD53 ACTR3 PLSCR1 CD80 HLA-H IL10RB RER1 PILRA NCF1C NAGK C17ORF62 HPS1 TNIP1 XXBAC-BPG246D15.9 GPR132 IKBKG SCO2 GK TRADD TFEB IFNGR2 NFKB2 RAB4B TOM1 PDCD1LG2 ELL LACTB NR1H2 AIP BAK1 MOB3A UBALD2 POLD4 SQRDL HTATIP2 SP140 CD82 ARPC5 ARAF NECAP2 SARS 4 Predicted Kinases Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). RPS6KA1 RIPK3 IKBKG ARAF SARS 3 Predicted GPCRs Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). CCR5 CCR1 GPR132 SARS 3 Predicted Ion Channels Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). SARS-CoV-2 is the virus causing the disease COVID-19 (novel coronavirus disease-2019). TRPV2 MCOLN2 CLIC1 SARS-CoV 110 Literature-Associated Genes from Geneshot GeneRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). TICAM2 GOT1 UBB CASP6 CD209 IFNAR1 IL1B BCL2L1 EEF1A1 IL6 MAPK3 RB1 SFTPD CD14 DPP4 IFNA1 FGL2 POU5F1 CCL2 CCL5 CD34 EGR1 TMPRSS2 CTSL IL17A NUDT2 VCP MAP1LC3A NMI TNF KPNB1 IRF3 KPNA2 DDX5 DDX58 VHL TBK1 RCHY1 IL1A HLA-DQA2 MPP5 CXCL10 CCND3 ACE2 IFITM3 TLR4 CXCL16 EZR PLA2G2D GPT AHSG ATF6 IFITM1 ZCRB1 DDX1 FCER2 ANXA2 HLA-B THPO RUNX1 KLF6 IFNG SMAD3 IFNL3 NFKB1 HMOX1 IL4 MAPK14 PHB2 OAS1 PKLR FCGR2A PTX3 HLA-DRB1 PSMC6 TP53 HLA-C ADAM17 RELA ACE STAT1 TRIM25 HLA-A CANX TMPRSS11D CLEC4G EIF2AK2 TMEM173 C11ORF74 APOBEC3G PHB NOS3 MASP2 CLEC4M PI4KB CXCL2 IFNB1 NPIPB3 ISG15 EGFR UBE2I MBL2 ICAM3 PPIA CASP3 CSF2 STAT6 MX1 MYD88 MAPK1 SARS-CoV 8 Literature-Associated Kinases Genes from Geneshot GeneRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MAPK3 TBK1 MAPK14 PKLR EIF2AK2 PI4KB EGFR MAPK1 SARS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CD209 IFNAR1 IL1B BIRC3 UBE2D2 IFNA1 FAM71D VCAM1 ANPEP TMPRSS2 UBD IRF3 DDX58 TBK1 UBC YWHAZ IL1A CXCL10 IFITM3 TMPRSS4 IFITM1 FCER2 ETV4 IFNG IFNL3 NFKB1 UBA52 OAS1 FCGR2A REG4 CTSD STAT1 TRAF3 IFITM2 B2M CLEC4G EIF2AK2 IL12RB1 TMEM173 ITM2A OASL CLEC4M IFNB1 ISG15 BDKRB1 ICAM3 MX1 TOP2B BCL2A1 ENO1 SERPING1 RPL9 SERPINB5 SERPINB2 RPL13A RPS18 ISG20 MT-CO2 TAGLN2 KHSRP IL4R DDX41 LGALS3BP RNASEL CD81 ITGB5 BST2 SLC11A1 LMNB1 CCNB2 GTSE1 IFI44 IRF5 MAFB BIRC5 C1QB EPSTI1 ITGA1 GAPDH MMP19 LDHA A2M MAVS MMP1 ACTB FCN1 RSAD2 OAS3 IRF7 CLEC5A IL2RB IFIT1 CLEC7A FCGR2B ALOX15 IFIT3 RTP4 TLR7 OAS2 PSMB8 DHX58 USP18 IFIT2 IL2RA IFI16 IFIH1 STAT2 ADAR SAMD9L IFNA4 INHBA IFI35 SOCS1 SAMHD1 UBE2L6 TLR3 PLAU CSF3 IRF2 FTH1 PSME2 RPL8 LY6E IRF1 DTX3L ATP6V0E1 IRF9 PSMB9 DRAM1 RPLP0 PPIB TAGLN IFI44L BNIP3 DDX3X DDX17 PSKH1 CREB5 IFNL1 TRIM22 IL22RA2 TLR9 IFITM5 HDAC1 PTMA PSMD14 TUFM GOT2 IL15RA TRIM56 CXCL11 IFI6 IFNL2 PLAGL1 DDX60 MX2 IFIT5 HERC5 GBP1 ETS2 GPT2 C1S SOD2 IFNA2 IFNA14 AIM2 PLSCR1 TLR8 PUM1 SF3B3 IL10RB RNF125 IFNGR1 HSPA1B GNA12 IFNA8 CFHR1 CD40LG SIAH1 IFNA17 RNF135 ITGA6 PGK1 TNFRSF25 SDHA IFNLR1 TNFRSF1B PIAS1 CA12 CALCR BAK1 PSMC5 DDX56 EEF1A2 IPO8 PRKCA KPNA5 DFFA HMBS IL26 SARS-Cov 6 Predicted Kinases Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). TBK1 EIF2AK2 RNASEL PSKH1 PGK1 PRKCA SARS-Cov 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PSKH1 SARS-Cov 2 Predicted GPCRs Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). BDKRB1 CALCR SARS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). TICAM2 F2RL1 JAK1 CD209 IFNAR1 MAPK3 IFNA1 CCL5 ANPEP STAT3 TMPRSS2 TNF KPNB1 IRF3 DDX58 TBK1 HLA-DQA2 DDX21 CXCL10 ESRRA TLR4 IFITM1 FCER2 KLK3 ST14 ETV4 GGT1 USP13 IFNG ERG IFNL3 NFKB1 IL4 OAS1 FCGR2A CTSD TP53 ADAM17 STAT1 IFITM2 B2M TMPRSS11D CLEC4G EIF2AK2 TMEM173 APOBEC3G OASL CLEC4M IFNB1 ETV5 ISG15 MBL2 ICAM3 SPI1 CASP3 STAT6 MX1 MYD88 MAPK1 TNFSF10 MDM2 KHSRP RNASEL AKT1 LMNA TYK2 HLA-E EZH2 AREG E2F2 ADAM15 IRF5 ICAM5 CXCL8 MYC MAVS AXL CRB3 MEF2C ELF4 CASP2 IFNW1 FCN1 CREBBP CUX1 RSAD2 OAS3 IDO1 IRF7 ZBP1 TAP1 CCL20 FCGR1A IFIT1 STAT4 IFIT3 TLR7 OAS2 XAF1 PSMB8 IFIT2 IFI16 IFIH1 STAT2 SOCS3 ADAR IFNA4 CASP4 SOCS1 SAMHD1 C5AR1 TLR3 ETS1 PLTP IRF1 ICAM1 IRF9 PPIB DDX3X ICAM2 RAN CALR RAB11A MKNK2 CD9 IFNL1 TLR9 HTR2B LMAN1 HDAC1 GOT2 ZNF512 MMP9 TLR2 TRIM21 TAPBPL USP25 AZI2 IFI6 CRABP2 IFNL2 AMFR MX2 CASP7 SIKE1 PMAIP1 TICAM1 CSTB RHBDF2 FAS IFNA2 CASP8 HNRNPA1 ADAM19 C4B TLR8 IFNGR1 IFNA17 ZDHHC1 SKP2 PTPN1 CGAS C4A FCN2 SEMA4D CD209B DHX36 GATA1 MASP1 COLEC11 PLAGL2 PRKCD TYRO3 PPP3R2 RUBCN IFNAR2 TRIM32 IKBKE CD209A PLA2G6 HC KPNA1 FCN3 RANBP2 UBA2 CDK9 PIAS1 STARD7 MFSD2B TGFBRAP1 EEF1A2 KPNA5 GGT2 MAPKAPK2 PHGDH IL11RA1 SAE1 OAS1A OAS1B SARS-Cov 15 Predicted Kinases Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). JAK1 TBK1 EIF2AK2 MAPK1 RNASEL AKT1 TYK2 AXL MKNK2 PRKCD TYRO3 IKBKE CDK9 MAPKAPK2 MAP3 SARS-Cov 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MKNK2 SARS-Cov 3 Predicted GPCRs Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). F2RL1 C5AR1 HTR2B SARS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). UBE2D2 PSMD8 SNX1 EXOSC3 UBE2K SWI5 YIF1A SARS SRP54 RAB8A ALG5 PSMD4 NUTF2 ALG8 RAB1A TSR2 PGM2 TIMM44 SPTLC1 ACO1 ZNF410 URM1 UNC50 COQ5 ADPRH SNX3 VPS25 AR PSMD6 GOLPH3 PREB PSENEN COX17 SYF2 ANAPC13 PFDN6 PSMD3 SLC39A1 ARF1 VPS35 VPS26A SUPT5H UPF3A PIN4 COX14 TAF11 SLA POLR2G APOO GEMIN2 SARNP PSMD13 UBE2N TTC1 COPS5 PPP1R7 ZMAT2 TPRKB SDHAF2 TRAPPC3 TAF13 POLR2J AHSA1 ACTR10 PSMD14 SNX4 TMEM50A UBA3 TAX1BP3 TSEN34 TXNDC12 SF3A3 RRAGC ZMPSTE24 TRIM21 WAS HSCB NUDT1 TAF10 ADH6 ZPR1 POP4 POLR2C FBXL5 ACOT8 NUBP1 PEF1 VPS45 WDR82 ALG1 SDHA TIMM23 VTA1 HIKESHI UFD1 GLRX3 TWF1 PSMD7 TRAPPC1 COQ6 ANAPC11 SYS1 PFDN1 COPZ1 PSMD9 PHF5A PSMD11 SAMM50 THUMPD1 SNRPD3 TADA3 EXOSC10 COQ9 POLR2H RAB35 FTSJ1 SCFD1 PSMG2 SNF8 VPS29 YEATS4 RNF113A EXOC1 ERVK21 RER1 SEC13 TIMM21 SUGT1 TRAPPC4 YKT6 SURF4 UBL4A SUPT4H1 PLAA EXOSC1 ACTR1A ANAPC10 VPS36 TXNL4A PPA2 SLC31A1 RTCA GTF2H5 TIPRL TRNT1 ACP1 PET100 RANGRF COX11 TEN1 TSG101 USB1 SSU72 PPP1R8 RMDN1 GLE1 EXOSC7 RNF5 SCO2 STARD7 GDE1 COX16 TMEM199 PRPF6 GPN3 UBE2Z RBM22 GPN2 ZNRD1 COQ2 TAF9 UCK1 PLRG1 TTC4 USP39 ALG3 GID8 SNW1 TP53RK SMPD2 TMEM165 FCF1 VIPAS39 PWP1 COX20 COQ4 PEX19 SCO1 COX19 ACTR6 FMC1 CRLS1 GON7 HM13 STX18 ERVK19 IFT20 HAGH TOMM22 GORASP2 SARS-Cov 2 Predicted Kinases Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). UCK1 TP53RK SARS-Cov 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). TP53RK SARS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). JAK1 CD209 IFNAR1 UBE2D2 FAM71D DDX10 SUMO2 TMPRSS2 GHITM IRF3 KPNA2 DDX58 TBK1 UBC CXCL10 UBE2K IFITM3 IFITM1 PFKL FCER2 UBA1 OAS1 STAT1 TRAF3 IFITM2 CLEC4G EIF2AK2 PCK1 OASL CLEC4M IFNB1 TBKBP1 ISG15 MBL2 ICAM3 MX1 AK4 RPS11 RPL13A COX7C ISG20 KHSRP UNC93B1 RNASEL CD81 BST2 TYK2 IFI44 IRF5 MAFB BIRC5 EPSTI1 C2 LDHA CST7 TRAT1 MAVS IRF8 IFNA13 RNF26 FCN1 RSAD2 OAS3 CLEC4C IRF7 NLRC5 NUSAP1 IFIT1 CLEC4A FCGR2B CD207 IFIT3 RTP4 TLR7 OAS2 XAF1 CLEC6A PSMB8 DHX58 USP18 IFIT2 IFI16 CLEC4E HERC6 IFIH1 STAT2 GBP2 SAMD9L IFNA4 IFI35 UBE2L6 TLR3 UBA7 IRF2 PSME1 PSME2 RPL8 LY6E HNRNPM IRF1 DTX3L ATP6V0E1 IRF9 DRAM1 RPLP0 PPIB IFI44L TAPBP DDX3X RPL15 DDX17 IL3RA ICAM2 TUBB2A PSKH1 CREB5 IFNL1 TRIM22 IFITM5 UBE2S CKB UBE2N TUFM UBA3 LDHB MXI1 THOC1 ARGLU1 IL15RA TRIM56 TRIM5 ASCC3 IFI6 IL32 IFNL2 LAMP3 DDX60 RNF19B HNRNPA2B1 MX2 IFIT5 HERC5 SAMD9 GBP1 GPT2 TICAM1 IFNA14 CD53 TRIM16L PLSCR1 SPRR2E STAB1 TLR8 RNF125 HSPA1B GNA12 IFNA8 IFNA17 RNF135 PSMC4 ZDHHC1 CGAS MASP1 IFNAR2 KPNA1 FCN3 RANBP2 COLEC10 UBE2J1 CD93 RGPD2 TANK IFNLR1 MYCN IFNA21 UBE2H C3ORF14 RIOK3 APOBEC3F ZDHHC11 THAP12 PIAS1 IFNGR2 IFITM10 TRAPPC10 DDX56 KPNA5 BDH1 LDHC AK3 NUP153 ZMYM4 GOT1L1 LDHAL6A DHX35 PSMC3 TNFAIP1 SPDYC MIR7-3HG LSM14A SARS-Cov 9 Predicted Kinases Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). JAK1 TBK1 PFKL EIF2AK2 RNASEL TYK2 PSKH1 RIOK3 AK3 SARS-Cov 2 Predicted Dark Kinases Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PSKH1 RIOK3 SARS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MVP GMIP NMI LYN HLA-B ZBTB7B LAP3 NLRP6 RBCK1 OAS1 HLA-DRB1 HLA-C STAT1 TRIM25 HLA-A FMNL1 TTC38 NUB1 SPI1 STAT6 MX1 MYD88 STXBP2 MGAT1 LCP1 TNFSF10 APOBEC3A ISG20 UNC93B1 ARHGAP30 ITGB2 LSP1 MYO1G IL4R PARP10 VASP RPS6KA1 CD37 TYMP CYBA SHKBP1 BST2 PSD4 ADGRE5 TYK2 HLA-E SYNGR2 IFI44 IRF5 EPSTI1 BATF2 ELF4 BCL3 HELZ2 OGFR ARHGAP27 HCLS1 CD48 SASH3 OAS3 IL10RA IRF7 DENND1C NLRC5 LCP2 TAP1 RASAL3 PIK3R5 SECTM1 RAC2 CORO1A VAV1 FCGR2B IFIT3 RTP4 TLR7 OAS2 PSMB8 CCR1 DHX58 USP18 CMPK2 OSCAR IFIH1 MLKL STAT2 PML TCIRG1 GBP2 PARP9 PARP12 SAMD9L HSH2D CASP4 NOD2 IFI35 PARP14 TRAFD1 UBE2L6 UBA7 SP110 IRF2 PSME1 PSME2 SHISA5 LY6E IRF1 PSMB10 RHOG SIPA1 DTX3L IRF9 PSMB9 IFI44L ARPC3 LITAF CD74 TALDO1 LIMD2 LAPTM5 LRG1 HCK THEMIS2 NCF4 EFHD2 SIGLEC7 RGS14 TRIM22 CYTH4 TNFRSF14 ZNFX1 TLDC2 RIPK3 TAP2 CSK CASP1 IL15RA TRIM21 GSDMD SELL TDRD7 TRIM14 NCKAP1L WAS SNX20 ACAP1 PRKD2 C19ORF66 LGALS9 MX2 TRANK1 GBP1 RELB ETV7 APOL3 BTN3A1 HLA-DPA1 MSRB1 CNPY3 ARPC4 GPSM3 PTPN6 CSF2RB CD53 HLA-DPB1 ADAM8 NCF1 APBB1IP IL10RB PRKCD FUT7 PILRA NCF1C NAGK C17ORF62 CD300A TNIP1 XXBAC-BPG246D15.9 SH3BP1 ARHGAP9 SCO2 NADK NCF2 GK NCF1B FCGR3A RGS19 PIK3CD AQP9 ARHGAP45 FGD3 TRADD NFKB2 BAK1 UBALD2 SP140 PI4K2B GSTK1 STK10 CYTH1 SARS-Cov 11 Predicted Kinases Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). LYN RPS6KA1 TYK2 MLKL HCK RIPK3 CSK PRKD2 PRKCD PIK3CD STK10 SARS-Cov 2 Predicted GPCRs Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ADGRE5 CCR1 SARS-CoV 242 Literature-Associated Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CASP6 JAK1 IL2 CD209 IFNAR1 TRIM55 IL1B BCL2L1 IL6 ENDOU SARS2 DPP4 FKBP1A EIF3F FGL2 POU5F1 CCL2 CD34 ANPEP STAT3 EGR1 TMPRSS2 CTSL GHITM SQSTM1 VCP TNF KPNB1 IRF3 KPNA2 DDX5 HIST1H1C DDX58 TBK1 RCHY1 MPP5 COPB1 CXCL10 CCND3 ACE2 IFITM3 TLR4 CXCL16 CTLA4 PLA2G2D ANXA3 AHSG ATF6 IFITM1 AGTR2 DDX1 RASA3 FCER2 ANXA2 HLA-B FURIN EPS15 RUNX1 JAK2 BAG3 KLF6 IFNG SMAD3 IL4 SERPINE1 PHB2 OAS1 AGPS COPB2 ADAM17 RELA TMPRSS11A ACE STAT1 TRIM25 TRAF3 HLA-A IFITM2 CLEC4G DEDD APOBEC3G EIF4E NEDD8 MASP2 CLEC4M CXCL2 PPIG TGFB1 ISG15 EGFR PPIH APP FKBP1B ICAM3 PPIA CXCL9 CASP3 PLP2 EDEM1 IL10 CDK2 STAT6 MX1 MYD88 ADH5 ADK ATF5 IKBKB CAV1 ALB SGTA CXCL1 CFTR PATJ SLPI CEACAM5 AKT1 BST2 TYK2 SMAD7 CEBPA CTSB MSR1 C1QB CD163 GAPDH CCR2 CCR3 CXCL8 PTGS2 IGFBP3 MYC MAVS AXL FGF7 LAMP1 GABARAPL1 CD63 CXCR3 CD69 IRF7 CD5 CD27 GP2 IFIT1 CCR5 CD2 TLR7 CD86 XAF1 CCR1 CD19 DHFR IFIH1 STAT2 SOCS3 NFIL3 ARG1 TLR3 PCBP2 FOS MAP1LC3B ICAM1 NFKBIA PPIB ICAM2 ATF4 ARF1 GNS SMAD4 PGLS DDIT3 NOS2 GP6 TLR9 AICDA IFITM5 CYP4F3 IL11 FOSB UCHL3 ATG5 CDK4 MMP9 CDCA7 ABL2 TLR2 CASP1 CD40 TFRC TAC1 SMG1 GBP1 CD83 CEACAM1 RELB HLA-DRA CCR7 CASP8 HNRNPA1 ADAM10 CD44 NCF1 CD68 HRC TLR8 TRAF6 TANK TIRAP ITCH CRP IGF1 BCL2L14 UCHL1 CAMK2D USP33 SP8 NPC1 AGO2 USP14 CASP5 EIF2AK4 DNM1L CASP9 HBA1 CREB1 KIT DICER1 NKX2-1 FAIM POMC EEA1 FOXJ1 KIR2DL3 CDK6 TNFSF11 BSG CXCR4 WIPI2 PARP1 XBP1 TFEB SARS-CoV 17 Literature-Associated Kinases Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). JAK1 TBK1 JAK2 EGFR CDK2 ADK IKBKB AKT1 TYK2 AXL CDK4 ABL2 SMG1 CAMK2D EIF2AK4 KIT CDK6 SARS-CoV 8 Literature-Associated GPCRs Genes from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). AGTR2 CCR2 CCR3 CXCR3 CCR5 CCR1 CCR7 CXCR4 SARS-CoV 1 Literature-Associated Ion Channel Gene from Geneshot AutoRIF Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CFTR SARS-Cov Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CD209 IFNAR1 FKBP1A IFNA1 FAM71D CMA1 VCAM1 ANPEP SEC14L1 GHITM SQSTM1 UBD IRF3 HIST1H1C DDX58 TBK1 MME CXCL10 ACE2 IFITM3 RNPEP ANXA3 IFITM1 NBR1 RASA3 FCER2 USP13 IFNL3 OAS1 REG4 STAT1 TRIM25 TRAF3 IFITM2 CLEC4G EIF2AK2 IL12RB1 TMEM173 OASL CLEC4M MOV10 PPIG IFNB1 CD8A ISG15 PPIH THOP1 FKBP1B ICAM3 TMPRSS13 CXCL9 PLP2 MX1 MYD88 IKBKB MT2A RPL9 TSPAN6 SLPI CCL8 ISG20 UNC93B1 DDX41 LGALS3BP RNASEL USP19 CD81 BST2 TYK2 CAPG IFI44 ADAP2 IRF5 C1QB EPSTI1 LTA4H MMP19 CPA3 MAVS AGRN TPD52L1 MMP8 F2R CASP2 CXCR3 RSAD2 OAS3 IRF7 NLRC5 CLEC5A IL2RB FCGR1A IFIT1 XCL1 CCNF IFIT3 RTP4 TLR7 OAS2 DHX58 USP18 IFIT2 IL2RA IFI16 HERC6 IFIH1 TNFAIP6 STAT2 ADAR MCOLN2 SERPINA3 IFI35 SAMHD1 UBE2L6 TLR3 PLAU IRF2 PSME2 LY6E IRF1 MYL12A DTX3L NFKBIA ATP6V0E1 IRF9 PPIB IFI44L DYNLT3 PSMA6 PSKH1 GNS PHLDA1 TRAF1 IFNL1 TRIM22 IFITM5 RFC4 UBA3 TRIM56 TRIM14 TFRC CXCL11 IFI6 IFNL2 DDX60 MX2 IFIT5 HERC5 SAMD9 GBP1 IGFBP1 TICAM1 HLA-DRA IFNA2 EIF4A1 TRAF5 AIM2 ADORA2A TLR8 PUM1 RNF125 IFNGR1 HSPA1B CCL22 CD40LG RNF135 OTUB1 IRAK1 PRKCD TRIM32 TRAF6 TANK RIOK3 USP33 HBA1 TNFRSF1B TRIM63 CA12 CTSF AKR1D1 OTUB2 FAM111A RNF11 TAX1BP1 B4GALNT4 USP5 BAK1 ADAM22 OTUD1 RYR3 FBLN1 CALCOCO2 SULF1 VTN PIK3C3 SEC16A FADD ATG12 TRIM11 USP4 SARS-Cov 2 Predicted Dark Kinases Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PSKH1 RIOK3 SARS-Cov 3 Predicted GPCRs Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). F2R CXCR3 ADORA2A SARS-Cov 2 Predicted Ion Channels Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MCOLN2 RYR3 SARS-Cov Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). TICAM2 CD209 IFNAR1 MAPK3 DPP4 IFNA1 CCL5 CMA1 ANPEP STAT3 TMPRSS2 SQSTM1 MAP1LC3A IRF3 DDX58 TBK1 MME CXCL10 ESRRA ACE2 IFITM3 TLR4 RNPEP IFITM1 TMBIM1 YWHAE FCER2 SLC6A19 NDRG1 IFNG IFNL3 NFKB1 IL4 MAPK14 USP2 ENPEP OAS1 CTSD ADAM17 FASLG RELA STAT1 TRIM25 TRAF3 IFITM2 AGT CSNK2A2 TMPRSS11D CLEC4G EIF2AK2 AGTR1 TMEM173 UTS2 CLEC4M IFNB1 ISG15 ICAM3 SPI1 CXCL9 LNPEP MX1 MAPK1 RPS6KB1 TMBIM4 CREBL2 IKBKB DEDD2 BCL2 IFI27 YAP1 HIST1H1D TAB2 GRINA AKT1 CD81 CTSB E2F1 CENPW CXCL8 MIB2 CDKN1A NOTCH1 MAVS BAD AXL MTOR IRF8 IRF4 CTSC CREBBP TNFRSF1A CXCR3 RSAD2 IDO1 IRF7 CD28 FCGR1A IFIT1 FCGR2B RYR2 IFIT3 OAS2 USP18 IFIT2 IFIH1 STAT2 SOCS3 TNFRSF12A FOSL1 SOCS1 TLR3 UBA7 ETS1 IRF1 THRA IRF9 LUC7L3 DDX3X SP3 CD9 IFNL1 IL27 TNFRSF14 PRPF3 PPP3CA PPP1CC ZNF512 HAMP PCSK1 CD40 TRIM21 CXCL11 IFI6 IFNL2 HERC5 GBP1 IGF1R SIKE1 RALB CHUK PNISR ETS2 CEACAM1 TICAM1 CSTB FAS IFNA2 FUT4 OPTN TRIM26 ADAM10 TNFRSF8 CXCL12 AIMP1 IFNGR1 CCL22 CGAS CD209B TYRO3 PPP3R2 BDKRB2 IKBKE TRAF6 TANK RIOK3 IKBKG DOK3 CREB1 DPP8 BACE1 TRIM63 TAX1BP1 PCSK2 RYR1 FAIM2 MMP14 PELI1 NFKB2 CALCR STARD7 NEDD4 NR2C2 MFSD2B TFR2 PAX5 RAB4B TGFBRAP1 MRPS12 GTF3C3 CALCOCO2 TRIM11 TRP53 HACE1 CYLD ROBO3 TRAF2 SMURF1 WIPI1 SPP1 SARS-Cov 2 Predicted Dark Kinases Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CSNK2A2 RIOK3 SARS-Cov 4 Predicted GPCRs Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). AGTR1 CXCR3 BDKRB2 CALCR SARS-Cov 2 Predicted Ion Channels Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). RYR2 RYR1 SARS-Cov Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SRP19 UBE2D2 PIGS ERLEC1 SNX1 GOLGA7 RNPEP ZCRB1 RAB8A ALG5 RAB14 SELENOS ERP44 SDF2 SLC30A7 TDP2 RARS RAB1A RAB5C SPTLC1 GPAT4 STT3A RMDN3 TMEM127 SRPRA PIGK SCAMP2 HSD17B4 SEC11A SEC23B VPS25 TMOD3 RAP1A GOLPH3 SFT2D1 AIDA TFG PSENEN ADIPOR1 SYF2 ANAPC13 RNF114 TM9SF2 FNTA HEXA RAB11A GYG1 PRPSAP1 TVP23B VTI1B VPS35 VPS26A RAB9A RAB5A GLOD4 TMEM147 UBE2A TXNDC17 PSMD13 UBE2N TTC1 PLGRKT ARFIP1 SAR1A TMEM230 UCHL3 GSKIP YIPF3 FAM96A SYPL1 ACTR10 SNX4 AP3S1 GTF3C6 TMEM50A UBA3 TXNDC12 SRI ZMPSTE24 SPPL2A VPS4B GINM1 RALB FAM103A1 COPG1 RSU1 SERP1 TMEM214 POP4 FBXL5 PEF1 VPS45 UFD1 TWF1 PSMD7 PFDN1 COPZ1 THUMPD1 EXOSC10 RAB35 SCFD1 VPS29 RER1 SEC13 OLA1 SUGT1 SURF4 PLAA ACTR1A VPS36 PPA2 RTCA TRNT1 RPE TSG101 SACM1L GLE1 TAX1BP1 STARD7 ARCN1 HARS ESD PSMD5 ERP29 HSFX3 PLEKHB2 GBA UBAP1 FAF2 TMEM11 API5 SETD3 GRSF1 STXBP3 SLC9A9AS1 TXNL1 GNAI3 ADPGK YIPF1 HMOX2 XPNPEP1 SH3GLB1 SEC22B TBRG1 STARD3NL SPG21 PITPNA ANXA7 SNX6 PLPBP TMEM165 FCF1 IFT20 GORASP2 PI4K2B RAP2C RNF181 RNF34 FAM32A RNF13 UBA6 SUCLG1 WDSUB1 ZDHHC13 PPCS PPP4R1 AKIRIN1 SKA2P1 RAB21 STX12 TMEM9B SLC35F5 TMEM43 UBE2F APIP HPF1 YIPF5 SNRNP27 SLC30A5 FUNDC2 TM9SF1 RFK RNF115 NTAN1 SYAP1 COX7BP1 TMEM183A RTFDC1 YIPF4 GALNT1 SLC35A4 TMEM167B TMX2 ZNF330 SEC23IP SZRD1 FAM192A SMIM12 HMGB1P3 UBE2R2 SARS-Cov Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CD209 IFNAR1 FKBP10 FAM71D SEC14L1 GHITM SQSTM1 UBD IRF3 DDX58 TBK1 CXCL10 ACE2 IFITM3 ANXA3 IFITM1 NBR1 USP13 IFNL3 USP2 OAS1 STAT1 TRIM25 TRAF3 IFITM2 CLEC4G EIF2AK2 TMEM173 OASL CLEC4M MOV10 IFNB1 TBKBP1 ISG15 MAP3K1 ICAM3 PPIA CXCL9 PLP2 MX1 MYD88 TRIM23 IKBKB TENT5C SLPI ISG20 UNC93B1 RNASEL USP19 FKBP8 CD81 BST2 APOL2 CCNB2 FKBP9 IFI44 ADAP2 IRF5 EPSTI1 RRAS TRAT1 MAVS SH2D3A B3GNT3 GABARAPL1 IFNA13 FZD9 RSAD2 OAS3 CLEC4C IRF7 NLRC5 IFIT1 CLEC4A CCNF FCGR2B RYR2 CD207 IFIT3 RTP4 TLR7 OAS2 XAF1 BCL2L15 DHX58 USP18 CMPK2 IFIT2 IFI16 CLEC4E HERC6 IFIH1 STAT2 MCOLN2 PARP12 IFNA4 IFI35 TRAFD1 UBE2L6 TLR3 UBA7 IRF2 PSME1 PSME2 LY6E IRF1 DTX3L IRF9 PPIB IFI44L PSMD3 ZMYND11 ICAM2 PSKH1 PHLDA1 CYP2S1 PPIC IFNL1 LDB3 TRIM22 ZNF436 IFITM5 ACIN1 ATG5 RFC4 UBA3 MXI1 FKBP4 CREB3L4 TRIM56 TRIM14 GPR183 CXCL11 IFI6 IFNL2 DDX60 DIRAS3 RNF19B C19ORF66 MX2 IFIT5 HERC5 SAMD9 GBP1 TICAM1 RHBDF2 TRAF5 PDLIM3 AIM2 TLR8 RNF125 IFNGR1 HSPA1B GNA12 IFNA17 RNF135 PSMC4 CGAS IFNAR2 TRIM32 TRAF6 COPZ1 TANK IFNLR1 TMED7-TICAM2 TRADD TRIM63 TAX1BP1 B4GALNT4 IFNGR2 EIF3D FKBP11 NDUFB1 ATG9A IFITM10 COPA RAB22A TRAPPC10 HAUS8 FKBP3 FKBP1C PPID ZBTB38 BAK1 OTUD1 RYR3 ATG12 TRIM11 USP4 UVRAG ZNF569 GNG3 ZNF629 ZNF763 ZNF44 ESYT3 CALHM6 ZNF501 CREB3 PPM1A SARS-Cov 1 Predicted Dark Kinase Gene from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PSKH1 SARS-Cov 2 Predicted GPCRs Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). FZD9 GPR183 SARS-Cov 3 Predicted Ion Channels Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). RYR2 MCOLN2 RYR3 SARS-Cov Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MOGAT2 SLC10A2 CES2 FCGRT TM6SF2 MVP ANPEP PRAP1 ADAMDEC1 VDR NMI BTNL3 DGAT1 HNF4G LILRB2 CEACAM20 MYO1A SLC7A7 GBA3 SLC22A18 XPNPEP2 LYN ACSL5 FABP2 SLC5A1 SLC6A19 HLA-B ZBTB7B KCNQ1 CDHR5 LAP3 MEP1B NLRP6 AMN CLDN15 ENPEP SLC7A9 BTNL8 CLRN3 OAS1 DEFA6 HLA-DRB1 STAT1 TRIM25 HLA-A CLCA1 TDP2 MGAM ADGRG7 MEP1A PLB1 ALDOB TTC38 LILRB1 NUB1 STAT6 CDHR2 MX1 MYD88 STXBP2 MGAT1 LCP1 TNFSF10 IGSF6 APOBEC3A ISG20 UNC93B1 MYO1G IL4R PARP10 TRPV2 VASP RPS6KA1 TYMP CYBA BST2 PLEKHO2 PSD4 SLC15A3 HLA-E TMEM150B IRF5 CTSZ EPSTI1 BATF2 ELF4 BCL3 ARHGAP27 MAPK13 HCLS1 SASH3 OAS3 IL10RA IRF7 LCP2 TAP1 LILRB4 PIK3R5 SECTM1 RAC2 VAV1 FCGR2B CCL13 OAS2 SIGLEC1 PSMB8 CD274 APOL6 CCR1 DHX58 USP18 CMPK2 OSCAR PTAFR IFIH1 MLKL STAT2 PML TCIRG1 NFKBIE GBP2 PARP9 PARP12 NOD2 IFI35 PARP14 UBE2L6 SP110 IRF2 IRF1 PSMB10 RHOG DTX3L IRF9 PSMB9 GBP3 HLA-DQB1 LITAF TAPBP TYROBP IFI30 LAPTM5 EHD1 HCK EFHD2 SIGLEC7 TRIM22 TNFRSF14 ZNFX1 PPP1R18 HSD17B11 TLDC2 RIPK3 TAP2 CASP1 IL15RA TRIM21 GSDMD TDRD7 TRIM14 RNF19B C19ORF66 LGALS9 MX2 GBP1 RELB ETV7 APOL3 MOB3C ARPC4 CD53 PLSCR1 NCF1 APBB1IP CD68 CD80 HLA-H IL10RB PRKCD PILRA NCF1C NAGK TNIP1 XXBAC-BPG246D15.9 GPR132 NCF2 GK OSTF1 HLX TRADD IFNGR2 NFKB2 ELL LACTB MOB3A UBALD2 POLD4 SQRDL ARPC5 NECAP2 SARS-Cov 7 Predicted Kinases Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). LYN RPS6KA1 MAPK13 MLKL HCK PRKCD RIP3 SARS-Cov 4 Predicted GPCRs Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ADGRG7 CCR1 PTAFR GPR132 SARS-Cov 1 Predicted Dark GPCR Gene from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ADGRG7 SARS-Cov 3 Predicted Ion Channels Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by the coronavirus SARS-associated coronavirus (SARS-CoV). Coronavirus disease (COVID-19) is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). KCNQ1 CLCA1 TRPV2 Up regulated gene from COVID-19 infected bronchoalveolar lavage from patients Differentially expressed genes from bronchoalveolar lavage from patients infected with COVID-19 POU5F1 TEX35 CRX OR1F1 ESR1 CHP2 RNLS PLEKHA5 INTU ALDH6A1 MYO6 FRK APOBEC3A SRD5A1 AKIP1 SKA1 ABCC9 SLC38A1 ERVW-1 CASR OR11A1 CENPK KLRD1 BRIP1 LACC1 KYNU MRGPRX3 MAB21L3 NEGR1 HNRNPUL1 ACADSB HYAL1 DNM1P41 RPAP2 FAM90A1 TOR1AIP2 TMEM212 ACP6 ORC4 RBM34 ZNF426 SOD2 LPAR6 P2RY10 ZKSCAN3 TRAPPC3L TBX18 SAA2 NFE4 EXD1 KIAA1257 IFNLR1 CD82 AK3 FBLN1 WDPCP ZNF471 DAB1 LOC107987372 CES3 MTRNR2L6 LOC112268387 RDH16 TIGD1 SMYD3 PCDHA4 NNT FBLIM1 NUDT8 ZNF34 SCNM1 LRRK1 WTIP LOC101929601 ZNF875 ZNF66 DENND2A NXNL2 MTRNR2L3 ABCB11 STXBP5L LOC105374103 AMN1 LOC105372269 LOC107987004 ASTN2 GEMIN8 ZNF665 ADH4 IGFL4 MYORG COX6B2 CCDC92 LOC107987377 LOC105371063 ANKRD18A C17ORF113 ADAM20 FBXO27 C12ORF45 EPHA10 USP17L11 LOC112268395 C21ORF62 SYN3 MCFD2 PDE6A HAPLN4 CFAP298 LOC107987394 CHRM3 ELOA3C TPM1 TBCCD1 LOC105379417 SCD5 PNPO LOC112268284 NXN ATP23 AIG1 DMC1 DUX4 TBXA2R C12ORF50 LOC107987364 VSIG1 AP5Z1 GSTO2 CADM2 ACBD7 DTNB SHISA9 PPHLN1 EPPIN KCNJ15 GTDC1 LOC105369189 DCUN1D2 LOC101930047 PCDH11Y LOC107987363 LOC112267959 DYNAP ELOA3D Down regulated gene from COVID-19 infected bronchoalveolar lavage from patients Differentially expressed genes from bronchoalveolar lavage from patients infected with COVID-19 CD14 ATP6AP1 ANPEP COMT ATP5MG CAPN2 ACADM COPB1 ATP6V1A CCND3 AP3B1 AATF ATP6AP2 COLGALT1 ANXA2 AP2M1 ANXA11 BRD2 CALM3 ACAA1 CALM1 COPB2 ATP1B1 ADAM17 ACE ACADVL B2M CNDP2 AGTRAP CD4 CAT AGPAT2 ARF6 CHMP2A BRI3 ADH5 ATP6V1B2 ARHGAP18 CD55 C20ORF27 CHMP2B BCL2A1 ATP6V1G1 BTF3 ATOX1 AIF1 COPS9 CHCHD10 BAX ARHGAP30 ATP1A1 ARF3 BANF1 AQP3 C1QC C1QA AKT1 APOL1 ALOX5 CD37 CD81 ADA2 BST2 B3GNT7 ADGRE5 APH1A ARAP1 ARHGDIA CMTM6 ABCC3 ABHD2 CD101 CCT5 C1ORF43 C3AR1 C1ORF162 ATP5MC3 CAPG CEBPA C14ORF119 AP2S1 ALCAM ANXA5 ATP6V1F CAPNS1 BLVRA C1QB CES1 CD163 CCT8 C2 APOL4 CLTA ATP5PB ATP5F1B CLDN7 CBR1 ACO2 ALDH9A1 ATP5F1C CLEC12A AKR1C3 A2M CCL4 ARFGAP3 B4GALT1 CKS1B APLP2 AXL ABCG1 CISH ACTB CD300C CHURC1 CAPN1 CD63 CEBPB COLEC12 ARHGDIB CLEC4A CLEC7A CCL24 CFD CD86 CD274 APOL6 CCR1 CASP4 C5AR1 AIDA APOC2 CD59 BTG2 CLIC4 CNN2 ACTG1 AKR1A1 ATP6V0C CHMP4B ADIPOR1 CAPZB ARL2BP ATP6V0E1 ANAPC13 CHCHD2 CA2 BCAP31 CCT2 BTG1 ALDH1A1 ARPC3 ARPC2 ARL6IP4 C1QBP ABRACL CCNI CCT4 CETN2 BRK1 CD74 CNBP CCT3 ATF4 CALR ATP6V0B CFL1 ARF1 CDIPT ALOX5AP CAPZA2 ANXA1 CFDP1 ANAPC5 CHCHD1 CD164 BEX4 CD151 CD9 CACYBP BNIP3L CBX3 ARRDC4 AOC3 B3GNT5 CMIP BHLHE40 CDC42EP3 ANP32A ATRAID ALAS1 BABAM1 CDC123 ATP6V1E1 CHMP5 CIB1 ARL6IP5 ATP6V1D ATP6V0D1 CHMP4A COPRS COPS5 CDC26 ATIC BCAS2 CKLF AHSA1 BUB3 AMD1 APEX1 BZW1 CCT7 AKR1B1 CERS2 AMIGO2 CDK4 ARL6IP1 ARGLU1 BLCAP CASP1 ATF6B CCRL2 ACTN4 BIN2 CCDC28A AMFR CD302 CAB39 CD58 ACOT7 BTK CD83 CCDC47 ARPC1B COPG1 ANP32B ALDOA CNPY3 ALDH2 COPE CLIC1 ARPC4 CHP1 BLVRB CD52 CD53 CALM2 ADAM10 ACTR2 CD44 ACTR3 BACH1 APOE APBB1IP CD68 ACP5 ACTR1A ACP1 C8B APOBR AQP9 CARD16 ARL2 CDK9 ARF5 BSG ATP2A2 ADPGK AP1B1 APMAP COPA AIP BAK1 ARPC5 COQ2 CALCOCO2 AKIRIN1 APIP ALAD ATP6V1H CHMP1A APOC1 CALCOCO1 ARL8B AUP1 ADSS2 BOLA2B ATG3 ATP5MF CITED2 CMAS BHLHE41 ALDH3A2 ATP1B3 ATP5MD ARPC1A CHMP1B ASAH1 CCPG1 ACOT2 AKIRIN2 CDC42 ATP5MC1 ABHD16A ATP5MPL CNPPD1 CLTC CMPK1 C9ORF78 AURKAIP1 BTBD1 COPS6 COA4 AHNAK CDC42BPB ARMT1 ATP5PD CLCN7 CAPZA1 ARF4 CGGBP1 CMTM3 ARL8A B3GNT2 ATP5F1E ADPRS ACOT1 CMTM7 CLN6 C4ORF3 BLOC1S2 BUD31 C6ORF62 CAPRIN1 CD33 CCL18 C19ORF53 CHKB BLOC1S1 CDC37 COMMD1 C9ORF16 CLN3 BST1 CLPTM1 APRT ATP5F1A BECN1 ABHD12 CIRBP CIAO2B ACAT1 CDK5RAP3 AARS1 CIAO2A ACKR3 ANOS1 BNIP2 CD99 ATP5PF CCDC115 CLNS1A ALDH3B1 ADTRP CCT6A ATP5IF1 C11ORF98 ATP5MC2 ACAA2 AVPI1 COMMD3 ANXA4 CHMP3 CNPY2 CDC42SE1 COA3 ALKBH5 COMMD6 ATP5PO CCZ1B CIAO1 ABHD5 C5ORF15 C11ORF58 ATP5ME Gr5vs Gr 4 unknown BIRC3 CXCL5 LYN FAM162A CHP2 IL22RA1 CXCL6 SAMD12 PRSS23 PTPRZ1 TGFBI CEBPA FABP5P7 CXCL8 CDHR1 IMPA2 FAM84B KRT14 MAF FOXN1 CCL20 SLC7A8 C3 KYNU NEFH XDH GBP6 ASAP3 CALML3 ICAM1 FABP5 SERPINE2 BLMH FLG NSG1 ALOX12B IL23A DLG2 HSPA2 MN1 ELMOD1 BEAN1 BID C5ORF46 FETUB VNN1 MT1X C10ORF99 NCEH1 PANK1 KANK4 KRT6C ADAMTS9 SLC6A14 SH3TC2 SLC13A5 AMDHD1 RAB5B IRAK3 NELL2 AC139769 RPL17-C18ORF32 LTB4R KRT10 KRT9 RPTN KRT1 LGALS7B TGM3 IL37 XCR1 LOR AL391121 HEPHL1 AL133352 POLR3G C5AR2 THEM5 CSRP2 AC129492 DEGS1 BOC DSC1 LPCAT4 DSG1 POU3F1 GGCT SERPINA12 AC006262 AC092809 KRT2 LINC01181 ZC3H11A HRNR CA6 ARL5A GSTA4 SLC46A2 GPR1 chloroquine-7251 from Old_CMAP_down chloroquine is currently used as a treatment option for COVID-19 but it mechanisms of action are poorly understood. MAPK3 RIPK1 CLIP4 FOXA1 FBP1 FBXO3 SLC25A40 POLI SMPDL3A SLC25A23 TRPM2 OLFML2A MPP6 ZNF574 IL7R CNKSR1 MYO19 MST1R NLK EN1 KIF13B C7ORF43 ZNF862 COCH C5ORF28 GFPT2 PSENEN TMEM120B C8ORF60 KCTD9 GLCE TRIM21 RNF31 RBBP5 GPATCH1 PILRB METTL2B ZNF304 TAF15 TMEM62 SOBP P2RX5 ZDHHC13 ZNF629 TIGD6 MTRF1 C11ORF71 MANSC1 C11ORF80 ZNF804A PLEKHJ1 GPR110 KRT75 JMJD4 PIGH LOC171220 C19ORF28 STK25 TBC1D17 SLC25A10 TMEM209 ERN2 ORAI3 MPST SUZ12P ERCC5 TINF2 CTNNBL1 FAM86A DPY19L2P2 C17ORF91 ZNF230 ISL1 CCS MID1IP1 ARMC6 TMEM177 GAB2 ABHD8 SMARCB1 STBD1 DBF4B NDE1 ABHD4 ZNF701 HOXC8 FAM193B ORC1L C14ORF45 RPGR ZNF324 MFF XPNPEP3 TPCN1 TTC23 EPHA4 URGCP GTPBP6 KIRREL FIP1L1 chloroquine-1719 from Old_CMAP_down chloroquine is currently used as a treatment option for COVID-19 but it mechanisms of action are poorly understood. PTBP2 GOLGA3 CLCN6 PTPN4 PIGK PIP5K1C BSDC1 CIC KCTD3 B4GALT2 ABCD3 MINPP1 CCNE1 PLCD1 CASZ1 FBXO5 MS4A6A KIF20B CLEC7A SELP SAMHD1 SERPINE2 GLOD4 RFPL3 MSL2 UBE2M CIDEB TIPIN TSEN34 IER3IP1 NUDT9 TOB1 PIK3C2B EMD SNX15 FAM46A TRMT12 GPR183 ACTN4 ANKRA2 ZNF223 RPL23AP32 BLVRB B3GNT1 ANAPC2 ZIM2 CHRNA2 NACAP1 IFNA17 CSTF3 TMEM43 TMEM183A CHMP1A TINF2 GTPBP6 WIT1 COMMD10 THAP7 DDX54 NDUFAF4 C20ORF20 PHKG2 TSPAN14 IP6K2 MRPL52 C4ORF41 MPP3 LOC202181 NUBP2 MTG1 STRA13 KIAA0247 PAQR3 C8ORF51 CHST4 PARP6 LOC100288387 ST3GAL5 ANKRD11 AVEN C19ORF24 NACC2 PARM1 EFTUD1 DNAJB14 ASAP1 RAB3IL1 NIP7 ZFP30 UBE2NL SUV39H1 CHST10 MAN2C1 GPR109B MCM9 OR7E37P FAM114A2 LOC80054 NIPA2 LY75 chloroquine-2869 from Old_CMAP_down chloroquine is currently used as a treatment option for COVID-19 but it mechanisms of action are poorly understood. FGF23 CHPF MOGS RNF2 TDRD1 CD8A HYI DNALI1 PARD6B NFAT5 SYBU LMNB1 ADAM15 B4GALT2 SERPINF1 PTK6 F2R TYRP1 PACS1 HIST1H2AJ INCENP ZNF442 EIF2S3 MED18 FAM189A2 SSR3 ZNF205 CCRN4L DNAJA4 GRB7 HIST1H3B ETV6 TFF2 DLST HIST1H4E TH GUSBP3 GTF2H3 DNAJC3 ZBTB33 PDK1 SLC16A10 HLA-J LYL1 ARRB1 TMEM209 ERN2 SUZ12P LOC202181 USP36 LOC390998 POLH ATP8B1 KIF13A MGC12488 CARD8 STAG3L1 IRF2BP1 MYOZ3 PHC3 ERCC4 ITFG2 ATP7A XYLT2 XRCC2 NOS1AP HNRNPUL2 KIAA0894 LOC100291860 FLJ10213 SUV39H2 EHMT1 TRMT2B MPHOSPH8 ZNF41 HAUS2 DKFZP547G183 LOC285830 MTA2 FFAR2 TTLL1 NKX3-2 ZFHX2 LOC100288007 TBX19 ZNF587 DCAF13 ZNF669 GUCY1B2 SLC12A8 C14ORF93 PDP1 HOXC4 RIN2 FLT4 DCAF4 TSPAN5 RCBTB2 FLCN ZNF350 chloroquine-7012 from Old_CMAP_down chloroquine is currently used as a treatment option for COVID-19 but it mechanisms of action are poorly understood. ARRB2 IFITM1 TDRD1 WFS1 PCSK7 HIST1H1D SLC25A23 SYBU TMEM184B PIP5K1C TWF2 CAPG MPP6 AKR1C3 DSCAM BMP4 CISH MITF HIST1H2AJ IRF7 FCHO1 VAV1 RFTN1 DDIT3 ERMAP TMEM185B GJA1 C19ORF40 KLF3 C3ORF52 VEGFC SNAPC2 EFNA3 MAP3K14 ELOVL4 RNF31 CRISPLD2 CCNT1 RPL13P5 METTL2B B4GALNT1 TGFB3 FSD1 DHX35 C19ORF28 FAM86A MTA2 TRMU HELZ PTCD2 ZNF668 ANKZF1 LRRC20 NARFL PET112L C12ORF51 TSPAN1 HIRA DIP2A FAM118A LIN37 C16ORF62 ZNF816A SETD8 DGCR11 FAM188A EML4 HOXC11 PLEK2 DHDDS SPINK4 C14ORF132 C2ORF34 ZNF268 ZNF14 OPA3 INPP5E EPHA2 ETAA1 MTHFSD FAM108B1 MED24 ASPHD1 HSD17B1 KCNS3 RAC3 SLC35C1 LOC100288413 ZNF8 RASSF1 ECHDC2 ZBTB10 PCDHA6 ARHGAP10 DYNC2H1 AGPAT3 WDR44 THBS3 CCDC21 AHCTF1 500 up regulated genes in A549 cells infected with COVID-19 extracted from GSE147507 A549 cells infected with COVID-19 extracted from GSE147507 with BioJupies Series 2 TM4SF20 SUMO1 IL1B TBCA HDAC2 RSRC2 IL6 HSPA5 CCL5 SUMO2 UGT1A7 NMI NUP54 CXCL5 SLC27A2 ITGB1 DDX5 DDX58 EIF2S1 IL1A DDX21 SHQ1 IFITM3 SLU7 ANXA3 IFITM1 AP3B1 DDX1 HSPA4 HLA-B LAP3 EHBP1 HSP90AA1 LARP7 FAM162A NCK1 OAS1 RDX HLA-C FN1 PLOD2 STAT1 TRIM25 IFITM2 B2M PRIM1 EIF2AK2 USP48 OASL EIF4E CXCL2 PPIG ISG15 FRMD3 PAICS MX1 MYD88 NOL7 RBM39 PAIP1 CD55 BCL2A1 MNAT1 SLITRK6 CP CXCL1 KRT18 RPL9 ASS1 MYO1B IFI27 DUSP16 TNS4 CFH C1ORF116 EVA1C SEMA3A SLPI ZNF467 ISG20 LCN2 EHF TAB2 PARP10 LGALS3BP APOL1 PIGK TYMP BST2 SLC16A3 RHOB EXO1 C5 HSD17B4 IFI44 EAF2 FAM72D CCT8 LTA4H SLFN11 CEP55 BATF2 LDHA CA11 PTGS2 FAM131B IGFBP3 ZNF184 KLF10 CDH1 EDN1 SULT2B1 EREG DKK1 GMPS NUCB2 HIF1A HELZ2 HSD11B1 PDLIM5 SMARCA1 SAA1 OAS3 IRF7 CFB FANCI NLRC5 TAP1 CCL20 ERCC6L CKAP2 IFIT1 STAT4 CTSS MASTL TNNI3 IFIT3 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 PSMB8 APOL6 C1R KYNU USP18 CMPK2 IFIT2 IFI16 CLEC4E FGL1 HERC6 IFIH1 CCDC18 STAT2 STON1 CACNA1G PML PLEKHA4 FGG ADAR NAMPT PARP9 PARP12 SAMD9L SERPINA3 IFI35 PARP14 HAS2 SAMHD1 UBE2L6 UBA7 SP110 CSF3 RBP7 TSC22D1 PSME1 PSME2 THBD UQCRB IER3 ICAM1 DTX3L NFKBIA IRF9 GBP3 CYB5A PLIN2 EFEMP1 LUC7L3 IFI44L DNAJC8 PAIP2 BNIP3 FHL1 FDX1 CHORDC1 ERRFI1 DNAJA1 PSMA6 FSTL1 SELENBP1 THEMIS2 PHLDB2 SAT1 SUB1 CACYBP DEK ESF1 FGB AOX1 SYT1 SERPINI1 PTGER2 TNFAIP3 STC1 FLRT3 TAF1D ZNFX1 HAT1 SUPT16H MMP10 PSMA4 HSP90B1 SARNP CNOT10 MTX2 TTC1 SUCLA2 CCDC58 NOP58 PI3 ANP32E PCNA C2ORF74 MSH2 SMARCA5 ZDHHC6 PAM GJA1 SSB STEAP1 BZW1 RPAP3 PNPT1 MAP4K3 AKR1B1 CBX1 USO1 GNL2 CWC22 ERVMER34-1 MXI1 MORC4 CCDC117 TCP1 INTS6 PDE4B ITIH2 ID1 MNS1 GSPT2 PIR MAP2 C15ORF48 GLCE SERPINB7 MLXIPL ODF3B MKKS NNMT TAP2 EBI3 TRIM21 RNF31 CREM ZC3HAV1 TDRD7 TRIM14 PDK4 MAP3K8 MORC3 ELOVL6 OLR1 TESC IFI6 PTGR2 PRPF38B BMPER IL32 PSIP1 LAMP3 DDX60 SMC3 WDHD1 TPR CCDC77 TFPI2 DNAJC7 C19ORF66 SP100 IFIT5 HERC5 TRANK1 RPL22L1 DDX60L SAMD9 USP44 GBP1 CASP7 EIF5B GINM1 ZNF624 IGFBP1 CCDC91 XRCC4 MAP3K14-AS1 THOC2 PLK2 CTNNAL1 NOSTRIN NUDCD1 SP140L C1S SOD2 BLZF1 CA9 MMD CASP8 MBD2 ADAM10 TRIB1 STK17A PAPPA TMEM130 PLSCR1 NCOA7 RARRES1 IFNGR1 PGK1 ORC2 TANK LARS MLLT3 B4GALNT4 GRSF1 FKBP14 AK3 APIP MCFD2 DMC1 POLR3G FIP1L1 FAM114A2 KTN1 KCNJ2 NEMF SNAP25 REV1 BCCIP C9ORF64 LTV1 ZCCHC7 NSRP1 SLC10A7 MSH6 CLDN1 TIGD2 CEP63 STAU2 VEZT GPCPD1 RBP4 ERAP1 LINC00473 MED6 DDX50 USP8 RBBP6 REC8 KIN SYCP2L EIF2AK1 SMIM3 CUL3 BBIP1 NYAP1 NFYB U2SURP DNAJB11 USP53 C4BPA PTER NT5C2 ZC3H15 FLJ37201 RPF1 DNTTIP2 PTP4A1 EIF3J PDIA3 ARHGAP24 ALDOC ZNF430 ACSL4 BTG3 ZNF326 GNL3 DPM1 USP3 KCNJ6 KRT222 DNAJC21 PON2 FILIP1 GTF2E2 MTA3 CEBPZ ZFP28 SNORD76 STT3B PRAME TXLNG ZNF558 DHRS4-AS1 C2CD4C SNAPC1 USP16 WDR75 CCAR1 CBWD2 ELAC1 TMEM123 WDR43 SOCS6 ANKEF1 SUSD2 PTCD3 FAM49B SNORD26 AKAP10 PNMA2 SLC39A8 DNAJC2 CCNYL1 P4HA1 BRIX1 GTPBP10 PDE1A WBP4 DHX29 SPATS2 ZSCAN30 HSPB11 PTPN2 CCNT2 TEX9 ZNF518B HNRNPD PITPNA-AS1 HERC4 MRPL33 ANKMY2 PTPN12 PLA2G4A ING2 THEM4 GOLGA4 TIGD7 CPSF3 CATSPER2P1 SMIM13 HLTF CWC15 TMCC1 KCTD6 FGA LLPH IFT81 SUZ12P1 SHOX2 SMS LRRC49 ZMYM2 CPS1 ZNF680 LOC374443 RIOK1 MSL3P1 CDCP1 THOC7 PPAT PPP2R2A MIOS GREM1 NUP62CL GABRA5 MARCH7 500 down regulated genes in A549 cells infected with COVID-19 extracted from GSE147507 A549 cells infected with COVID-19 extracted from GSE147507 with BioJupies Series 2 SLC36A1 PTPN14 MVP ANPEP SQSTM1 SPTAN1 STX3 TRIB3 TSPO SLC16A8 SLC22A18 A4GNT PMEPA1 ADA NPTX1 SIRPA SLC9A3 HMOX1 SERPINE1 TCN2 MTMR11 COL4A2 CTSD COL4A4 SFN MGAT4B RETSAT MEPCE PEPD PXN ZNF575 PLB1 TLN2 FRMD8 PLEC NEU1 MXRA8 ADHFE1 PLEKHA7 SAT2 GSTZ1 SAC3D1 NAGLU DANCR NT5DC2 KRT4 RAB40B NDUFB2 KIAA1217 MZT2A FNIP2 SLC2A1 KCNQ1OT1 TAGLN2 NADSYN1 MAPK8IP3 VPS37C ARHGEF10L HS1BP3 VASH1 DNAJB2 CAD CORO1B LMNA URM1 ORAI2 KCNAB2 INF2 TOLLIP SLC1A5 ABHD2 SLC38A7 MARVELD1 CORO2B MAFG SAPCD2 UAP1L1 TP53I3 TRPM2 SNX8 PRELID1 LINC00482 GNPDA1 TNRC6C MSC YPEL1 SOX13 COL1A1 CILP2 PKD1 EP400 SREBF1 AP1M2 CEP170B CARD14 RHOD WNT4 WNT9A NAV2 DVL2 DACT1 ARHGAP1 HERC2 UPP1 TRIOBP DYRK1B NBEAL2 RERE RNF44 CYHR1 MNT LFNG ULK1 SETD1B ATG2A MXD3 STAG3 PODNL1 IQGAP3 PREX1 PHF19 EFNA2 IGDCC4 LRFN4 AKR1A1 ADAMTS15 RPL10 TAGLN ISCU NUPR1 NSMF VIM SH3PXD2A IL3RA MXD4 WNK1 LBH PSKH1 FASN TPRG1L GEM FAM43B DDIT3 SLC25A25 TGFB1I1 DGKQ PPP1R15A QRICH2 COL20A1 PLA2G4C RTN4R VASN FOXK1 L3MBTL1 CLN8 BBC3 NEURL3 FAM161B CHAC1 WBP2 ATP6V0E2 CIB1 TMEM208 PTRHD1 ATP6V0D1 COPRS SPRED3 DCTN3 TIMP2 WDR83OS SUSD5 CXXC5 BEX2 CDK4 ARHGEF18 PLEKHG6 SRPK3 LENG8 COL7A1 VEGFB ITPKC NDRG4 NEURL1B PRRT2 MAP3K14 CHRNB4 FAM110A ITGA11 GJD3 CCDC78 GRIN2C C19ORF71 ACAP1 GCAT CDKN2C CYP4F11 PVRIG TESK2 CLDN14 ACP6 LONRF2 PLEKHA6 PDZK1 AHNAK2 MIR22HG CNNM3 ZBED1 TCTA TPRA1 DCST2 HERC1 TRPV1 ETS2 RRAGD VAT1 CERK COPE DYSF SNN PDXK MEX3B BMF LMCD1 LPIN1 ZNF469 ASH1L-AS1 OSGIN1 TNFRSF10D ADAM19 PKD1L2 LOC284454 NUMBL ESPNL ADRA1B IRAK1 HPS1 DOK3 NPC1 AGO2 IFITM10 CARS2 COQ4 RYR3 SLC35A4 NXNL2 AP5Z1 AHNAK CLCN7 ALDH3B1 LTB4R PLEKHJ1 ABHD4 ANKRD11 NACC2 FLCN TSPAN1 INPP5E CDH4 SLFNL1-AS1 NDOR1 NPAS1 DMPK CTAGE7P CDK10 DLL4 SPNS1 HMGXB3 TBL3 ACTR1B CAMKK1 KLHL21 COMTD1 PMF1 OBSL1 SCNN1D MEGF6 MEF2D RAP1GAP FBXW9 HTT JRK SGK2 KCTD7 ANKH ARID1B KIAA1024 MZT2B GGT8P AACS CEMP1 BCRP3 PAPLN MAP3K3 KCNC4 ADCK5 PRKAR1B MRPL23-AS1 SRRM2-AS1 ASMTL-AS1 ART5 HMG20B MIR3176 PINK1 ZNF524 ATXN1 TSPAN10 WDR81 FIZ1 FAM173A BCAT2 PGPEP1 BOLA1 TEP1 CYB5RL FLJ42627 TRIP6 TMEM91 PLCXD2 IGSF9B CCDC17 HOXB-AS3 GGN PCDHA11 MEG9 SYNE1 MDGA1 SLC16A13 ACAP3 ADI1 NEU4 ZNF324B ZHX2 PEX10 RALY RAB40A DUS3L PCDHA12 LOC100287036 ULK3 PRSS53 HERC2P3 HAPLN3 LOC646762 PCDHAC1 PPP1R3B CLTB MATN2 FAT1 DGCR6L GPRC5C ASNA1 PLEKHM1 HOXB6 STOX2 EEPD1 ABCB6 PTCH2 MARCH4 P2RY2 DDA1 PLK3 BEST3 ITPA VPS18 HECTD3 PEMT C16ORF58 SHH GAL HDAC5 FLII OTUD7A SLC7A11-AS1 WASH2P LOC100132356 NOXO1 RRN3P3 MIR600HG PRODH NR0B1 CHST3 APC2 IPO13 ENG NLGN3 EML5 TSTA3 NUDT17 PODXL LRP3 UNKL AKAP13 RABEP2 P4HTM TRAPPC6A POLE4 CHGA GLI4 PACS2 PRIMA1 SYNE2 AMH PHLDB1 GNPTG KIRREL3 CA5BP1 MAZ COL27A1 KCTD15 FA2H ATP9A SYNM NUDT14 SIRT7 SLC39A13 FBXL8 MLXIP LSS UCKL1-AS1 BAIAP2 TTLL12 RNF224 STX1B TAF1C THOC6 ZNF219 FAM102A MYEOV BTBD9 MVK SMPD1 AMDHD2 METRN FDXR KLHDC7A LOC646214 NCOR2 ASB1 IGLON5 RNPEPL1 CAPN10 TRABD2B SMPD3 POLR2A FBXO10 PANX2 PRADC1 SH2D5 CYB561D1 ATP13A1 CRTC1 DGCR9 SMIM5 MBD3 TET3 RPS19BP1 FBRSL1 FAM174B ARFGAP2 DSCAML1 FASTK FLJ16779 NIPAL4 PCDHGC3 MZF1 MFSD12 MRPL54 LOC100289230 C10ORF95 MPC1 PRRT3 TBC1D7 RHOBTB2 LOC100129534 KLC4 METTL22 NOX1 SNORD18C ZFYVE26 ADCY5 DDX39A SFRP5 PTPN18 ATP6V0E2-AS1 LOC100272217 SLC34A3 RNF185 MSI2 ALDH16A1 GLUD1P3 TELO2 SLC37A4 TMEM129 EPHB3 PDRG1 ZNF785 KATNB1 MFNG REPIN1 NECAB2 Healthy human lung biopsy vs. COVID-19 infected human lung series 15 from GSE147507 up genes Healthy human lung biopsy vs. COVID-19 infected human lung IL1B FAM8A1 FKBP1A FGL2 CCL2 NMI TNF DDX58 LILRB2 YWHAZ IL1A CXCL10 IFITM3 TLR4 PDZD11 CXCL16 ARRB2 TPM4 IFITM1 YWHAE LYN HLA-B GNG5 CDHR5 FAR2 F5 RAB8A TREML3P OAS1 SULT1B1 FCGR2A DMBT1 HLA-C STAT1 HLA-A IFITM2 B2M EIF2AK2 MGAM OASL USP15 ISG15 CD4 RPH3A SPI1 PLP2 MX1 CD55 BCL2A1 TPSB2 LCP1 SNTN CEACAM6 TMEM71 TNFSF10 PIGR SIX1 REPS2 HIST1H2BC MCTP2 FAM216B IGSF6 GCNT3 S100P GPX2 FDCSP METTL7B CXCL17 PNRC1 FREM2 TNS4 MARCKS STEAP4 APOBEC3A TET2 DLGAP1-AS1 HIST1H2BD CCL8 LCN2 DHRS9 HESX1 GABRP C1QC TOR1B VASP PTK2B SF3B4 CD37 VKORC1L1 MYADM HCAR2 TOP2A MILR1 VSIG10L LMO2 C3AR1 LMNB1 PLBD1 KCNE1 GLRX IFI44 RNASE2 C1QB EPSTI1 NME1 BRCA2 PADI2 GLDN HP HPR CERS6 SPTLC2 CLEC12A CHI3L1 CST7 SCARNA21 CCL4 CLC CAMP IL18RAP ABCC2 ACTB MMP25 LTF WNT7B TFAP2A ALPL MMP8 HLA-DRB5 MAP2K6 CTSC BCL3 FCN1 CBX4 ZNF385A SAA1 CD48 RSAD2 GPR65 OAS3 CD69 IDO1 IRF7 GNG2 ZBP1 SLAMF7 LCP2 SIRPB1 GBP5 TNFSF14 MS4A7 TLR1 HCST GPR84 CHIT1 FCGR1A IFIT1 ARHGDIB CLEC4A RAC2 STAT4 TNIP3 PTPRC LY86 CLEC7A IGF2BP3 CTSS FCER1G S100A9 ENPP6 IFIT3 RTP4 SFT2D1 CYP7B1 OAS2 PHF11 XAF1 APOL6 CCR1 CXORF21 GBP4 CYBB IL1R2 GPR141 IL1RN IFIT2 HBB CLEC4E PLAC8 TMEM52B HERC6 CLEC4D IFIH1 TNFAIP6 STAT2 PML CLDN2 CCL11 TREM1 NAMPT PARP9 SAMD9L GCH1 HSH2D CASP4 BASP1 CCL19 C5AR1 CSTA UBE2L6 SP110 IRF2 FTH1 PSENEN PFN1 LY6E ATP6V0C CRYAB IRF9 GBP3 DAZAP2 SFTPA1 SCGB1A1 SERPINE2 GABARAP IFI44L LITAF SERPINB9 SH3BGRL3 JUND CD74 TYROBP IFI30 CFL1 IL2RG ALOX5AP HCK NCF4 SAT1 NOP10 GTF2B CD164 CNTN1 RBM11 COL9A2 C1ORF194 SAMSN1 ZC3H12A LST1 SIGLEC7 BPI TRIM22 CR1 S100A12 CYTIP PGLYRP1 DCUN1D3 LRRK2 NTNG2 SEZ6L2 ADRA2A ANP32A PSMA4 MPV17 S100A11 SF3A2 PSME3 DYNLT1 CKLF SNX10 MXD1 PDE4B FLJ45513 HAMP NEAT1 MNS1 MSMO1 C15ORF48 ANXA2R CTF1 P2RY14 P2RY13 TNFSF8 S100A8 CASP1 CSF3R GCA TRIM21 ZC3HAV1 SELL TRIM5 PCGF5 POU2AF1 BCL11A WAS CTSE RHOH STAP1 OLR1 FPR1 CD38 PDGFRL PTMS ALDH3A1 HS3ST3A1 BIN2 CXCL11 ZMYND12 RP2 IFI6 LY96 MNDA CHRAC1 LAMP3 DDX60 RNF19B C19ORF66 LGALS9 TNFSF13B XRN1 MX2 IFIT5 HERC5 DDX60L SAMD9 GBP1 PSTPIP2 UCP2 CEACAM1 KLHDC7B ARL5B PATL1 NAPA SP140L C1S SOD2 VNN2 TRIM38 RABGAP1L PIK3AP1 RAB8B ARSE SERPINA1 SERF2 SRGN FCGR3B GPSM3 CSF2RB CDA CD53 GNLY PLEK LPAR6 EVI2B AIM2 FCGR1B SPRR2E HBA2 HRASLS2 APBB1IP NCOA7 VNN3 ZDHHC19 AMDHD1 LOC643802 HLA-J CA1 CORIN FCAR CDH2 CCL3 GATA1 CCL7 TIMM23 USB1 CLECL1 PILRA SIGLEC5 LILRB3 LILRA6 LILRA5 FGR STX11 GK FCGR3A SIGLEC14 AQP9 DOK3 CARD16 BCL2L14 CASP5 HBA1 TRPA1 CA12 PELI1 SP140 PI4K2B VSIG1 CAPZA1 C4ORF3 CCL18 BLOC1S1 FFAR2 KCNJ2 RBP4 SLC39A8 MGC12916 MROH8 CMC2 TREML4 NME8 CLEC1A TLE4 MCTS1 TAOK3 WIPF1 MIER1 POPDC3 CPLX2 IQGAP1 G6PD PIM2 F8A1 CYP19A1 RNU4ATAC OR7E14P LINC00605 DBNDD1 GMFG ACSL1 RGL4 HIST2H2BE BCL6 CARD17 LINC00639 TFEC ST20 RNU12 HCAR3 NEXN DAPP1 CCDC114 C20ORF203 YPEL3 AGMO RNU6ATAC LILRA1 LOC399715 OLIG1 STK24 PROK2 DNAH7 TENM1 LOC388813 EIF1B CHI3L2 RNU11 NBN ALPK1 ANKRD22 FCGR2C LBP GBP1P1 RGS18 HNRNPC CACNA1A KCNJ2-AS1 ATP7B ITGB2-AS1 STRN4 CYSTM1 SLC9B2 KCNH7 TPP1 JAK3 FHL3 MAP3K13 SYN1 MDH1B GAPT TARP CCDC71L VTRNA1-1 NFKBID HSPB6 SNORA48 TMEM154 SNORA74B RTN3 CEACAM3 KLK10 PPDPF C9ORF66 DNAAF1 SMAP2 PSEN1 SFTPA2 SLC26A8 CDR1 FLOT1 Healthy human lung biopsy vs. COVID-19 infected human lung series 15 from GSE147507 down genes Healthy human lung biopsy vs. COVID-19 infected human lung GAK CANT1 BCL2L1 EEF1A1 MPHOSPH10 ZC3H7A EGR1 FBXW5 SUN2 BCAR1 DDX5 TUBGCP2 MYO1D BAIAP2L1 GOLGA3 UBXN1 TMBIM1 RASA3 CUL1 NDRG1 TUBB4B MRPS2 BAG3 TUBA1A HMOX1 DNMT1 EIF4E2 TUBA1C TUBA4A SFN MEPCE HERPUD1 PES1 PPIG MOB2 HSPA8 USP7 H2AFJ ZBTB44 SCYL1 SGTA PLEKHO1 BAP1 BCL2L2 NEBL RPL41 RPS3A SLC25A4 RPSA ABLIM1 MEIS1 STARD10 CCND1 TMEM109 CD2BP2 PIEZO1 USF1 MICAL1 ATG4B DPP7 AKAP1 XAB2 ZC3H7B LDB1 SEC24C USP19 DNAJB2 ZDHHC7 QSOX1 BSDC1 EIF3B PLEKHO2 ZSWIM8 NDST1 SIN3B APH1A SMAD7 ITPKB PPP6R2 DDB1 ADAM15 KIAA0930 ARHGAP29 ACVRL1 MAFG CCT8 DOCK1 SMTN ADAMTS2 GRB10 HEXB UNC13B SH3PXD2B PRELID1 SEMA4C SLC25A29 PBXIP1 MYC GADD45G B4GALT3 KLF13 TRAK2 TGFBR2 PIK3IP1 GADD45B TRAK1 STAT5A PSMD6 SEMA3F ALS2CL ITPR3 PYGO2 TFIP11 WDR37 FZD4 FIBP HDAC3 CTR9 RGS3 UPP1 EDC4 C2CD2 PHC2 CYP1A1 PDE2A RPS28 TNS1 IER2 FOS SGK1 EIF3G DUSP1 ID3 EGFL7 GATA2 PXDC1 JUN CLDN5 CTGF RPL3 RPLP0 POLDIP3 SFTPC MAT2A CRIP1 LUC7L3 RPS5 NR1D2 VPS28 PPP1CA C1QBP NDUFS6 TCF21 HCFC1R1 SH3PXD2A EFNB1 CAMTA2 KLHDC3 HEXA RAPGEF3 ERRFI1 LBH STK38 SERPINB6 SELENBP1 SLC25A3 TPRG1L CCNL2 CTDSP2 FAM160B2 GUK1 S100A13 MYZAP CCDC85B RRAD AKAP17A SLC25A25 STARD9 MYCT1 F2RL3 TCERG1 GJA4 ROBO4 SNHG15 STC1 SERTAD1 MAFF FOSB ZNF263 CIB1 TMEM208 CKB NRBP1 ASL C12ORF57 EBNA1BP2 BCOR TSPAN4 PSMC1 MGLL TUBB6 GNL2 SF3B5 SPSB3 DNAJB4 ODC1 EIF2B5 MFAP1 MLH1 RANGAP1 PAN2 ARRDC2 ITPKC BLCAP GALNT18 RND1 DEXI MUL1 NUDCD3 PPP3R1 RNF31 DLL1 MEDAG DLST INPP1 RARRES2 GOLGA8A PER1 FAM13B MCM7 AMFR DNAJC7 KIF3B ATRX EIF2B4 ST6GALNAC6 SLC25A36 RALBP1 ARPC1B ENO2 PDXK THAP2 RALGDS GRPEL2 NR4A1 TMEM255B CSPG4 MCAM COL12A1 HLA-H GNA12 GET4 ANAPC11 EXOSC7 TXLNA CTCF CDK9 BCR KDM1A PRMT1 PGF NFATC2 MMP14 QARS PRKAB1 GRSF1 SPRYD3 SEPHS1 AIP CD82 PSMC5 DDX56 MAPKAPK2 SAE1 PSMC3 TNFAIP1 CYTH1 ROBO3 WIPI1 FAM32A SLC35A4 ZNF330 CHMP1A AHNAK CDC42BPB CDC37 CIRBP URGCP EHMT1 MPHOSPH8 ANKZF1 FAM118A RASSF1 ARHGAP10 PTCD3 DHX29 ZMYM2 DLL4 HMGXB3 ACTR1B MEF2D ULK3 PLEKHM1 ITPA ENG PODXL PHLDB1 MLXIP THOC6 ASB1 DDX39A MFNG MADD TRPC4AP HDAC7 ZFAND2B PARVB TANC1 FOXK2 RRP1 INPP5A ARHGEF7 E2F4 ZSCAN18 SSH2 PLXND1 PYCR2 PMM2 NOP56 RNMT PRDM2 PPP1R14B SKIV2L CXORF40B RRP12 ATP6V0A1 KCTD20 ATP6V0A2 CYC1 PXDN DCAF5 ENTPD6 CRY2 MYO9B CC2D1B RAPGEF1 SERTAD3 EPC1 GGA2 BRD9 ILVBL MAP4 LUZP1 MDC1 NFATC4 TAF1 HARS2 ELK3 SNAI1 PQLC1 SLC38A5 RXRB TTC7A METTL3 DAPK3 S1PR2 VPS13D MOAP1 SLC39A7 KCTD10 PCDH12 RHBDF1 KANK2 SRCAP CCM2 AMOTL1 AGAP3 ACP2 TSR1 TIMM13 FARP1 PPP1R13B FBXO31 TSPYL2 INPP5K LETM1 HBP1 UROD CHFR CTPS1 ADCY6 DKK3 VPS54 SMPD4 C19ORF48 NCAPH2 RBM6 MICAL3 SSH1 DST PELO STARD3 ADCY4 NOC2L TCF25 DTX4 GNL1 MFN2 TBC1D9 OSBPL5 ZNF160 UBE2J2 SLC9A1 SUN1 PDGFRB RAF1 PLEKHM2 NDUFA11 PLXNA2 SPRED1 ABR XPC NOL8 NISCH LRRFIP1 ABLIM3 KAT5 VSIG2 UTP6 RRP7A SASH1 URB1 FLNC LCN10 TBCD LRRC32 FHOD1 SGSM3 SLC25A44 GLT8D1 C6ORF106 USP22 EDC3 VPS37B GAS6 TTL PCID2 SNX11 LZTR1 BAALC NES MBIP LMBR1L TSSC4 CTTN ITPR1 SIVA1 UCK2 NASP ARHGEF15 DOCK6 TXNDC11 DDX42 PRKY GMPPA PPP1R12A PPP1R16B AFG3L2 SREK1 RSAD1 LRRC47 SGSM2 PSMD2 NAP1L4 HIPK2 FDPS GUCD1 FAM219B ZNF451 SPHK1 PCDH1 RBFOX2 LRIG1 RPS6KA2 WDR74 WBP1L ATP8B2 FAM214B MAF1 IFT43 PEX5 ERCC1 ARFRP1 SPG7 CCDC130 FXYD6 XRCC6 DCHS1 NAB2 ARAP3 MERS-CoV 38 Literature-Associated Genes from Geneshot GeneRIF Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease TICAM2 UBB DPP4 HSPA5 TMPRSS2 CTSL VCP IRF3 DDX58 RCHY1 ACE2 IFITM3 IFITM1 HLA-B FURIN ADA HLA-DRB1 TP53 TMPRSS11A TRIM25 HLA-A IFNB1 ISG15 TMPRSS13 PPIA CEACAM5 TMPRSS11E ATP1A1 SMAD7 PPARG SPINT1 IFIH1 C5AR1 RAPGEF3 CD9 FGF2 PRKRA IRAK3 MERS-CoV 2 Literature-Associated Kinases Genes from Geneshot GeneRIF Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. PRKRA IRAK3 MERS-CoV 1 Literature-Associated GPCR Gene from Geneshot GeneRIF Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. C5AR1 MERS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. IMPDH2 IFNAR1 IFNA1 ANPEP SEC14L1 TMPRSS2 UBD IRF3 HNF4G DDX58 EIF2S1 TBK1 UBC YWHAZ MME CXCL10 IFITM3 TMPRSS4 ANXA3 IFITM1 YWHAE IGSF3 ECSIT IFNG HSP90AA1 NFKB1 MAPK14 UBA52 OAS1 CTSD HLA-C FN1 ZDHHC5 STAT1 TRIM25 TRAF3 IFITM2 CANX B2M TMPRSS11D EIF2AK2 TMEM173 HERPUD1 ITM2A OASL ELK4 IFNB1 USP15 ISG15 HSPA8 TMPRSS13 CHMP2A PLP2 MX1 ATP6V1B2 RPL9 KLF5 PRKAA2 PRSS16 ISG20 ITGB2 IL4R LGALS3BP CD81 BST2 C3AR1 IFI44 IRF5 BIRC5 EPSTI1 MMP19 MAVS ABCF1 GADD45B ACTB SPINT2 EDN1 AGRN RARG IRF8 GCM1 RSAD2 OAS3 IRF7 IFIT1 IFIT3 RTP4 TLR7 HLA-F OAS2 PSMB8 GBP4 DHX58 IL1R2 USP18 IFIT2 IL2RA IFI16 NEFH HERC6 IFIH1 TNFAIP6 STAT2 ADAR MCOLN2 IFNA4 SERPINA3 INHBA IFI35 SOCS1 SAMHD1 UBE2L6 TLR3 PLAU IRF2 TFG LY6E IGFBP4 IRF1 TXN DTX3L PTPRM IRF9 PSMB9 HLA-DQB1 PPIB TAGLN IFI44L DDX3X EDN2 IFNL1 TRIM22 TNFAIP3 IFITM5 MMP10 RNASEH2A AKR1B1 HSPA1A TRIM56 ZC3HAV1 CXCL11 IFI6 IFNL2 DDX60 MX2 IFIT5 HERC5 SAMD9 GBP1 TICAM1 HLA-DRA C1S IFNA2 IFNA14 HLA-DPB1 ZNF177 AIM2 PLSCR1 ADORA2A MAS1L CORIN TLR8 PUM1 IL10RB RNF125 IFNGR1 HSPA1B GNA12 CDH2 IFNA8 PRDX2 RNF135 MTSS1 ITGA6 OTUB1 PGK1 DHX36 TRIM32 TRAF6 TANK RNF5 RIOK3 TNIP1 CA12 OTUB2 FKBP11 STX6 FCRL3 IL23R MEX3C TRIM4 HLA-DOB AP1S3 ANKRD17 TDGF1 TRAF3IP2 COG6 NLRP2 ELF5 DHX33 MERS-Cov 6 Predicted Kinases Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. TBK1 MAPK14 EIF2AK2 PRKAA2 PGK1 RIOK3 MERS-Cov 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. RIOK3 MERS-Cov 3 Predicted GPCRs Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. C3AR1 ADORA2A MAS1L MERS-Cov 1 Predicted Dark GPCR Gene from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. MAS1L MERS-Cov 1 Predicted Ion Channel Gene from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. MCOLN2 MERS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. TICAM2 CASP6 IFNAR1 MAPK3 DPP4 IFNA1 ANPEP TMPRSS2 SQSTM1 UBD PRKACA TNF IRF3 DDX58 TBK1 MME HLA-DQA2 CXCL10 TLR4 ARRB2 FAF1 YWHAE KLK3 ETV1 HLA-B ST14 ASPSCR1 AP2M1 IFNG ERG SMAD3 NFKB1 MAPK14 HLA-DRB1 CTSD HLA-C ADAM17 RELA STAT1 TRIM25 TRAF3 HLA-A IFITM2 AGT TMPRSS11D EIF2AK2 TMEM173 NEDD8 USP21 IFNB1 USP15 TGFB1 ISG15 TMPRSS13 USP7 MX1 MYD88 G3BP2 CAV1 IFI27 SERPINB3 NT5E TP63 MUC16 MDM2 THBS1 HDAC6 TYK2 EFTUD2 CTSB IFI44 ADAP2 HGF HLA-DQB2 KIR2DL1 KIR3DL1 CDKN1A SERPINH1 MAVS TGFBR1 SPINT2 SPINT1 OSM FGF1 IRF8 HLA-DRB5 CEBPB CREBBP PTPN22 RSAD2 IDO1 IRF7 NLRC5 TAP1 IFIT1 CCL13 CTSS IFIT3 TLR7 HLA-F PSMB8 DHX58 USP18 IFIT2 IFIH1 STAT2 ADAR IFNA4 NOD2 FAP TLR3 IRF1 IRF9 JUN HLA-DQB1 DDX3X HLA-DMA DDX39B LTA LIN28A VCPKMT TLR9 BAMBI PPP1CC MUL1 PCSK1 TAP2 GCA ETV6 TRIM21 USP25 AZI2 PLAC1 AMFR MX2 HERC5 SIKE1 TICAM1 HLA-DRA ERAP2 HLA-DPA1 ALDOA HLA-DPB1 OR2H2 CA1 RNF125 HSPA1B RNF135 SKP2 CGAS C4A PPP3R2 RUBCN IKBKE TRAF6 TSG101 RIOK3 TNIP1 ARHGAP45 KIR2DL3 PCSK2 MMP14 NEDD4 TFR2 TGFBRAP1 CD82 OTUD1 ROBO3 PRKRA ERAP1 KIN DHX29 METTL22 KCNH7 TDGF1 TRAF3IP2 HMGA2 COP1 SMAD2 NRF1 NFKBIL1 PDGFA METTL21A PUM3 HOXA2 KAT2B HMHB1 TRIM13 TSBP1 HEXIM1 MCCD1 PBRM1 KDM5D HLA-DRB3 TUBB4A MICA POLR3A ATP6V1G2 ITGA3 KIR3DL2 MERS-Cov 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. RIOK3 MERS-Cov 1 Predicted GPCR Gene from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. OR2H2 MERS-Cov 1 Predicted Ion Channel Gene from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. KCNH7 MERS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. SLC5A2 PPP1R14D RNPEP TMBIM1 SLC5A1 SDCBP2 GRIN1 ST14 ZBTB7B SARS RAB8A ANXA11 ALG5 PLCB3 SLC27A4 ERP44 TMPRSS11D TDP2 PTH PGLYRP3 PRSS47 ARF6 STAT6 RAB5C RNASE7 RAB25 TTC22 TMEM127 VPS37C SEC24C ZDHHC7 PSD4 UNC50 GALNS SCAMP2 HSD17B4 SEC23B ESRP2 HNRNPA1P27 CRB3 FAM160A1DT AR AP1M2 TMOD3 TMEM184A PTK6 SULT2B1 TRIM16 GIPC1 RHOD TNK1 FOXN1 OR7E91P TRPV6 SFT2D1 UPK2 TGM1 RABGGTA GLTP SMAGP RAB11A UBE2V1 TVP23B RAB9A RAB5A FAM187B PLD2 FUT2 TREX2 SLC35E4 PRR13 TXNDC17 UBE2N UCHL3 YIPF3 ETHE1 HEBP2 SSC4D PLEKHG6 GRB7 ARFIP2 RIPK3 TMEM139 STAP2 STYXL1 TMEM40 PER1 AMFR VPS4B TMEM159 GINM1 RALB REEP4 RALBP1 TMEM62 FUT4 SERPINB1 SDR9C7 PEF1 UFD1 TWF1 RAB35 RER1 SURF4 COPS3 SLC31A1 TSG101 HSFX3 GNPNAT1 GBA UBAP1 PRKAB1 FAF2 GRSF1 STX4 YIPF1 PPP5C HMOX2 XPNPEP1 RAB5B STARD3NL PITPNA ALG3 TMEM165 IFT20 TNFAIP1 PI4K2B RAP2C RNF181 ZDHHC13 TMEM9B SLC35F5 APIP RFK SMIM12 UBE2R2 SLC35C1 GTF2E2 HECTD3 SMPD1 RNF185 PMM2 SLC39A7 GUCD1 TRIM6TRIM34 SLC35A2 TNIP2 GALNT4 TGIF2C20ORF24 SGPL1 TNFRSF10A PRICKLE3 RNU252P ABHD17C RAET1G PUDP SNORD152 SRRM1P1 PITPNM2AS1 RPS6KA4 TBC1D3P1 AAGAB VSIG10 SNORD43 TAB1 GLRX3P2 PYM1 TRIP4 RAET1L PHLDB3 PSAT1P3 TCTN3 GNRHR APEX2 FAM83C OCLN SERPINB12 RMND5B PPARD SLC52A3 SHPK TMEM79 FAM3D PRSS27 GSDMA TMEM189 OR7E62P RNU6767P UNC45A WASL PRELID3B PPP2CB ST20MTHFS RIPK4 GPR108 SH3YL1 TERF1P4 TRIP10 TMCO4 TMEM30B MERS-Cov 7 Predicted Kinases Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. PTK6 TNK1 RIPK3 PRKAB1 RPS6KA4 TAB1 RIPK4 MERS-Cov 1 Predicted GPCR Gene from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. GNRHR MERS-Cov 2 Predicted Ion Channels Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. GRIN1 TRPV6 MERS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. IFNAR1 SEC14L1 TMPRSS2 UBD UBXN6 IRF3 DDX58 TBK1 HLA-DQA2 CXCL10 IFITM3 ANXA3 UBXN1 IFITM1 ST14 OAS1 TRIM40 HLA-C ZDHHC5 TMPRSS11A STAT1 TRIM25 TRAF3 IFITM2 TMPRSS11D EIF2AK2 TMEM173 NLRX1 ITM2A OASL NEDD8 IFNB1 USP15 TBKBP1 ISG15 TMPRSS13 PLP2 MX1 MYD88 OVOL1 HPN TRIM23 TENT5C S100A14 RPL19 ISG20 TMPRSS11E RNASEL CD81 BST2 EFTUD2 TRIM65 TOLLIP C1ORF43 IFI44 IRF5 EPSTI1 C2 ATP5F1B HLA-DQB2 ATP5F1C TRAT1 MAVS GADD45B SPINT2 SPINT1 B3GNT3 IFNK IRF8 IFNA13 HLA-DRB5 GCM1 RSAD2 OAS3 IRF7 GDF3 NLRC5 IFIT1 CLEC4A IFIT3 RTP4 TLR7 OAS2 XAF1 DHX58 CD5L IL1R2 USP18 IFIT2 IFI16 HERC6 IFIH1 STAT2 ADAR PARP12 IFNA4 IFI35 TRAFD1 UBE2L6 TLR3 UBA7 IRF2 PSME2 LY6E HNRNPM IRF1 DTX3L IRF9 HLA-DQB1 IFI44L RNF114 DDX3X PSKH1 CREB5 IFNL1 TRIM22 HCG9 TNFAIP3 IFITM5 CHAC1 UBE2N UBE2E2 MXI1 RNF31 TRIM56 TRIM5 IRAK2 ATP1A3 IFI6 IFNL2 DDX60 C19ORF66 MX2 IFIT5 HERC5 SAMD9 GBP1 DNAJC3 SIKE1 TICAM1 HLA-DRA IFNA14 TRIM26 CD53 HLA-DPB1 TRIM16L AIM2 PLSCR1 CORIN TLR8 PUM1 RNF125 HSPA1B GNA12 IFNA8 IFNA17 RNF135 OTUB1 CGAS DHX36 TRAF6 TSG101 UBE2J1 CD93 TANK TMED7-TICAM2 UBE2H RIOK3 OLFML1 THAP12 TNIP1 TIRAP OTUB2 RNF11 IFNGR2 MAP3K7 FKBP11 IFITM10 TRAPPC10 HAUS8 ZDHHC20 OTUD1 TRIM11 DHX29 MEX3C TRIM4 AP1S3 ANKRD17 ELF5 DHX33 PRSS8 OR2H1 WASHC5 RNF123 IRAK4 TMPRSS6 EMC7 ZFYVE9 HLA-F-AS1 TRIM62 MERS-Cov 8 Predicted Kinases Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. TBK1 EIF2AK2 RNASEL PSKH1 IRAK2 RIOK3 MAP3K7 IRAK4 MERS-Cov 2 Predicted Dark Kinases Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. PSKH1 RIOK3 MERS-Cov 1 Predicted GPCR Gene from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. OR2H1 MERS-Cov Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. CANT1 FCGRT MVP ANPEP CTDSP1 GMIP TSPO LILRB2 CXCL10 RIPK1 SLC7A7 TMBIM1 LYN ZBTB7B KCNQ1 LAP3 ANXA11 NFKB1 RBCK1 OAS1 HLA-C NUCB1 RELA TRIM25 HLA-A OASL SRC SPI1 STAT6 MX1 MYD88 RAB5C STXBP2 MGAT1 NINJ1 APOBEC3A ISG20 UNC93B1 MAN2B1 ITGB2 IL4R PARP10 TMEM127 VASP GRINA RPS6KA1 EMILIN2 GNB2 LRP10 TYMP CYBA CORO1B SHKBP1 BST2 PLEKHO2 MAP3K11 SLC15A3 ARAP1 HLA-E GRN HCAR2 SYNGR2 SCAMP2 RAB20 ADPRH IRF5 CTSZ EPSTI1 ABCD1 BATF2 CD300C PLAUR ELF4 STK40 TFE3 BCL3 CEBPB AP5B1 TNFRSF1A HELZ2 OGFR ARHGAP27 SBNO2 RAB43 MAPK13 OAS3 IL10RA IRF7 SLAMF7 TAP1 PIK3R5 SECTM1 CCR5 OAS2 SIGLEC1 CD274 CCR1 DHX58 IL1RN USP18 CMPK2 OSCAR PTAFR IFIH1 PML TCIRG1 NFKBIE GBP2 PARP12 NOD2 IFI35 SHISA5 LY6E IRF1 CHMP4B RHOG DTX3L IRF9 LITAF TYROBP IFI30 TALDO1 PIM3 PSAP LAPTM5 EHD1 HCK THEMIS2 EFHD2 SIGLEC7 SIGLEC9 CYTH4 TNFRSF14 ZNFX1 S100A11 PPP1R18 RIPK3 TAP2 CSK TLR2 CASP1 IL15RA TRIM21 GSDMD TDRD7 TRIM14 IFI6 METRNL RNF19B C19ORF66 LGALS9 MX2 GBP1 RELB ETV7 TICAM1 NAPA APOL3 N4BP1 MOB3C ARPC4 CD53 ADAM8 CD68 IL10RB PRKCD STX5 RAB35 PILRA NCF1C APOBR NAGK LILRB3 TNIP1 XXBAC-BPG246D15.9 SH3BP1 STX11 SCO2 NADK NCF2 GK AQP9 HLX TRADD IFNGR2 NFKB2 STX4 TOM1 ELL NR1H2 BAK1 SQRDL CHMP1A RNPEPL1 HCAR3 GPR108 MFSD7 SLC31A2 DTX2 EGLN2 MERS-Cov 12 Predicted Kinases Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. RIPK1 LYN SRC RPS6KA1 MAP3K11 STK40 MAPK13 PIM3 HCK RIPK3 CSK PRKCD MERS-Cov 1 Predicted Dark Kinase Gene from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. STK40 MERS-Cov 5 Predicted GPCRs Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. HCAR2 CCR5 CCR1 PTAFR HCAR3 MERS-CoV 1 Predicted Dark GPCR Gene from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. HCAR3 MERS-CoV 1 Predicted Ion Channel Gene from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. KCNQ1 MERS-CoV 72 Literature-Associated Genes from Geneshot AutoRIF Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. IFNAR1 IL6 ENDOU DPP4 STAT3 TMPRSS2 CTSL GHITM VCP TNF IRF3 HIST1H1C DDX58 TBK1 RCHY1 CXCL10 UPF1 ACE2 IFITM3 TLR4 ANXA3 IFITM1 RASA3 FURIN JAK2 ADA STAT1 TRIM25 TRAF3 HLA-A IFITM2 ISG15 SRC TMPRSS13 PLP2 IL10 MX1 MYD88 ATP1A1 RNASEL CD81 SMAD7 CTSB GAPDH MAVS MTOR MNT IRF7 IFIT1 CTSS TLR7 CD86 IFIH1 NOD2 TLR3 NFKBIA SP3 RAPGEF3 GNS CD9 UCHL3 ABL2 TFRC FGF2 CRP UCHL1 CAMK2D HBA1 EGF IRAK3 GLS KPNA4 MERS-CoV 8 Literature-Associated Kinases Genes from Geneshot AutoRIF Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. TBK1 JAK2 SRC RNASEL MTOR ABL2 CAMK2D IRAK3 MERS-CoV Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. IFNAR1 IL1B BIRC3 IFNA1 VCAM1 ANPEP SEC14L1 TMPRSS2 CTSL GHITM IRF3 HIST1H1C DDX58 TBK1 YWHAZ IL1A CXCL10 IFITM3 ANXA3 YWHAB UBXN1 IFITM1 RASA3 HSP90AA1 IFNL3 OAS1 CTSD FN1 STAT1 TRIM25 TRAF3 IFITM2 B2M EIF2AK2 TMEM173 NLRX1 OASL MOV10 IFNB1 USP15 CD8A ISG15 CXCL9 PLP2 MX1 MYD88 NAP1L1 ATP6V1B2 BCL2A1 ENO1 RPL9 KLF5 TSPAN6 CCL8 ISG20 UNC93B1 ITGB2 DDX41 LGALS3BP RNASEL BST2 ITGAL TYK2 VSIG10L LMNB1 IFI44 ADAP2 ANXA5 IRF5 EPSTI1 MMP19 CPA3 CDKN1C MAVS IFNK LAMP1 MMP8 IRF8 RSAD2 OAS3 IL10RA IRF7 ZBP1 NLRC5 PYCARD IL2RB IFIT1 CTSS IFIT3 RTP4 TLR7 OAS2 PSMB8 GBP4 DHX58 IL1R2 USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 TNFAIP6 STAT2 SOCS3 ADAR MCOLN2 PARP12 IFI35 SOCS1 TRAFD1 SAMHD1 UBE2L6 TLR3 PLAU IRF2 PSME2 RPL8 LY6E IRF1 NFKBIA IRF9 PSMB9 CTSH IFI44L DDX3X ZMYND11 IFI30 GNS TRAF1 IFNL1 TRIM22 OLFM4 TNFAIP3 TLR9 IFITM5 PTMA KPNA3 TRIM21 USP25 TRIM56 ZC3HAV1 TFRC INPP1 CXCL11 IFI6 IFNL2 DDX60 MX2 IFIT5 HERC5 SAMD9 GBP1 TICAM1 APOL3 IFNA2 CLIC1 TRAF5 AIM2 PLSCR1 ADORA2A TLR8 PUM1 IL10RB RNF125 IFNGR1 HSPA1B CD40LG RNF135 ITGA6 OTUB1 PGK1 IRAK1 DHX36 TRIM32 TRAF6 TANK IFNLR1 RIOK3 OLFML1 TNIP1 TIRAP HBA1 CA12 CTSF OTUB2 TAX1BP1 ANXA7 SULF1 PIK3C3 TRIM11 TPM1 IRF2BP1 TRIM4 DHX33 IRAK4 FDFT1 TNFRSF11A PRY SMARCA2 MERS-CoV Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. TICAM2 IFNAR1 DPP4 IFNA1 FGL2 STAT3 TMPRSS2 CTSL TNF KPNB1 IRF3 DDX58 TBK1 RHOA CXCL10 ESRRA RIPK1 IFITM3 TLR4 FAF1 IFITM1 ABL1 YWHAE KLK3 LYN NDRG1 ETV1 AP2M1 IFNG ERG SLC9A3 IFNL3 NFKB1 MAPK14 OAS1 CTSD TP53 ADAM17 RELA STAT1 TRIM25 TRAF3 IFITM2 EIF2AK2 TMEM173 PLAT OASL USP21 IFNB1 USP15 TGFB1 ISG15 SRC CAT CXCL9 MX1 MYD88 G3BP2 PCSK7 IKBKB CAV1 IFI27 HDAC6 TYK2 EFTUD2 CTSB IFI44 CTSZ CENPW MIB2 CST7 SLC2A4 MYC MAVS COL1A1 IRF8 CTSC RSAD2 OAS3 IRF7 IFIT1 CTSS REG3G IFIT3 TLR7 OAS2 DHX58 CTSK USP18 IFIT2 NMRAL1 IFIH1 STAT2 SOCS3 ADAR IFNA4 NOD2 IFI35 SOCS1 CSTA TLR3 ATP6V0C IRF1 IRF9 JUN CST3 CTSH GLUL DDX3X CALR CSNK1A1 CD9 ZC3H12A IFNL1 TNFAIP3 IFNA5 TLR9 DAP3 COPS5 UCHL3 HDAC1 UCHL5 PSMA7 PPP1CC MXI1 CSK TLR2 ETV6 TRIM21 USP25 DCP2 AZI2 CST1 CTSV IFI6 IFNL2 AMFR HERC5 SIKE1 CHUK TICAM1 CSTB IFNA2 OPTN TRIM26 TRAF5 RNF125 IFNGR1 IFNA17 ITGA6 OTUB1 CGAS PPP3R2 IKBKE TRAF6 TERF2IP TANK RIOK3 IKBKG DOK3 DPP8 BACE1 TAX1BP1 PELI1 NFKB2 NR2C2 TFR2 TGFBRAP1 CALCOCO2 TRP53 HACE1 CYLD ROBO3 TRAF2 PRKRA DHX29 RAP1GAP POLR2A NRF1 IRAK4 PLN MCCC1 ZFHX3 NLRP3 CST6 PDE3B GPATCH3 RNASEH2B IFNA11 RNF216 PELI3 PC PURA SELENOK CCL9 DHX9 TRF GSPT1 OASL1 MERS-CoV Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. PIGS SNX1 UBE2K RNPEP SARS GRPEL1 RAB8A ANXA11 ALG5 RAB18 RAB14 UBQLN1 ERP44 SDF2 SLC30A7 TDP2 RAB7A RARS TMED5 ARF6 RAB1A UBFD1 RAB10 RAB5C PTTG1IP TBCB STT3A RIC8A TMEM127 VASP SRPRA SEC24C ZDHHC7 TMED9 SCAMP2 SCARB2 HSD17B4 SEC23B ERLIN1 SNAPIN VPS25 ALDH9A1 TMOD3 RAP1A GOLPH3 TPP2 AIDA TFG ADIPOR1 RHOG GLTP VDAC2 RNF114 RAP1B TM9SF2 HEXA RAB11A PRPSAP1 TVP23B VPS35 VPS26A RAB9A RAB5A GLOD4 UBE2L3 PRKAG1 TMX1 UBE2N PSME3 TTC1 SAR1A CORO1C YIPF3 ACTR10 SNX4 AP3S1 SEC24B UBA3 USO1 GNA13 PTBP3 SRI RRAGC ANKRD13A ZMPSTE24 PTS SPPL2A PER1 AMFR VPS4B APPL1 GINM1 RALB YTHDF3 PIP4K2C PRRC1 RALBP1 COPG1 SNX12 RAB8B RSU1 ACTR2 ACTR3 PEF1 VTA1 UFD1 TWF1 PSMD7 COPZ1 RAB35 SCFD1 VPS29 RER1 SEC13 SUGT1 YKT6 SURF4 PLAA ACTR1A VPS36 RTCA RPE TSG101 RIOK3 TAX1BP1 AP3M1 STX7 ARCN1 ESD PSMD5 ERP29 PLEKHB2 GNPNAT1 GBA NUDT5 UBAP1 FAF2 TBC1D20 API5 SETD3 GRSF1 STXBP3 GNAI3 ADPGK AP1B1 YIPF1 PPP5C HMOX2 XPNPEP1 SH3GLB1 SEC22B RAB5B STARD3NL APMAP SPG21 PITPNA ANXA7 SNX6 TMEM165 GORASP2 TNFAIP1 RAP2C RNF181 FAM32A ZDHHC13 PPP4R1 RAB21 STX12 TMEM9B SLC35F5 TMEM43 UBE2F SLC30A5 RFK YIPF4 SEC23IP ARF4 RPF1 STT3B PPP2R2A SGPL1 PPP2CB WASF4P SNAP29 ACOT9 AGFG1 RAB6A SFT2D2 FAM91A1 ACBD3 UBE2Q1 PLIN3 SPCS3 ADSS RPSAP44 SNX2 ABRAXAS2 CPNE3 GMFB WDR1 MERS-CoV Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. IFNAR1 IFNA1 SEC14L1 TMPRSS2 GHITM UBD IRF3 HIST1H1C DDX58 TBK1 CXCL10 IFITM3 TLR4 ANXA3 UBXN1 IFITM1 DDX1 RASA3 IFNL3 NFKB1 OAS1 ZDHHC5 STAT1 TRIM25 TRAF3 IFITM2 EIF2AK2 TMEM173 NLRX1 OASL MOV10 IFNB1 USP15 TBKBP1 ISG15 CXCL9 PLP2 MX1 MYD88 RAB5C NAP1L1 TRIM23 PFDN5 TENT5C CCL8 ISG20 UNC93B1 RNASEL BST2 TYK2 TOLLIP VSIG10L IFI44 ADAP2 IRF5 EPSTI1 RRAS TRAT1 MAVS GADD45B SH2D3A B3GNT3 IFNK IRF8 IFNA13 RSAD2 OAS3 CLEC4C IRF7 NLRC5 PYCARD TLR1 IFIT1 IFIT3 RTP4 TLR7 OAS2 XAF1 GBP4 DHX58 IL1R2 USP18 IFIT2 IFI16 HERC6 IFIH1 STAT2 ADAR GBP2 MCOLN2 PARP9 PARP12 IFNA4 IFI35 SOCS1 TRAFD1 CSTA UBE2L6 TLR3 UBA7 IRF2 PSME2 LY6E IRF1 IRF9 CTSH IFI44L RNF114 DDX3X ZMYND11 PSMB4 CREB5 TRAF1 IFNL1 TRIM22 TLR6 TNFAIP3 TLR9 IFITM5 UBE2E2 UCHL5 UBE2G1 UBA3 MXI1 TLR2 RNF31 USP25 TRIM56 ZC3HAV1 ASCC3 AZI2 GPR183 IRAK2 CXCL11 IFI6 IFNL2 DDX60 C19ORF66 HNRNPA2B1 MX2 IFIT5 HERC5 SAMD9 GBP1 SIKE1 CHUK TICAM1 IFNA14 DEFA4 TRAF5 TRIM16L AIM2 PLSCR1 TLR8 PUM1 IL10RB RNF125 IFNGR1 HSPA1B IFNA17 RNF135 OTUB1 IRAK1 CGAS DHX36 IFNAR2 TRAF6 TANK IFNLR1 TMED7-TICAM2 IFNA21 RIOK3 OLFML1 TIRAP CTSF RNF11 TAX1BP1 IFNGR2 IFITM10 TRAPPC10 HAUS8 ACOD1 OTUD1 SEC16A TRIM11 CALHM6 IRF2BP1 DHX29 TREML4 MEX3C TRIM4 AP1S3 DHX33 RNF123 IRAK4 TRIM62 OTUD5 TRIM9 DEAF1 HILPDA MERS-CoV Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. FCGRT MVP GMIP DDX58 LILRB2 RIPK1 SLC7A7 TLR4 ARRB2 LYN HLA-B ZBTB7B KCNQ1 LAP3 SIRPA ANXA11 OAS1 STAT1 TRIM25 HLA-A FKBP15 OASL IL17RA LILRB1 SPI1 STAT6 MX1 MYD88 STXBP2 MGAT1 TNFSF10 NINJ1 IGSF6 APOBEC3A UNC93B1 MAN2B1 ITGB2 IL4R PARP10 TMEM127 ITGAX VASP RPS6KA1 LRRC25 EMILIN2 LRP10 TYMP CYBA PLEKHO2 MAP3K11 EHBP1L1 SLC15A3 ARAP1 HLA-E GRN HCAR2 HK3 IFI44 IRF5 CTSZ EPSTI1 ABCD1 BATF2 CD300C ELF4 STK40 BCL3 CEBPB AP5B1 TNFRSF1A HELZ2 OGFR ARHGAP27 SBNO2 RSAD2 OAS3 IL10RA IRF7 SLAMF7 LCP2 TAP1 PIK3R5 SECTM1 CCR5 CTSS IFIT3 OAS2 SIGLEC1 CD274 APOL6 CCR1 DHX58 CYBB IL1RN CMPK2 OSCAR CLEC4E PTAFR IFIH1 STAT2 PML TCIRG1 NFKBIE GBP2 PARP9 PARP12 SAMD9L CASP4 NOD2 IFI35 PARP14 SAMHD1 C5AR1 IRF1 DTX3L IRF9 LITAF TYROBP IFI30 PSAP LAPTM5 EHD1 HCK THEMIS2 EFHD2 PICALM FPR2 SIGLEC7 SIGLEC9 CYTH4 TNFRSF14 ZNFX1 PPP1R18 RIPK3 TAP2 TLR2 CASP1 IL15RA TRIM21 TDRD7 MNDA RNF19B LGALS9 MX2 TRANK1 DDX60L GBP1 RELB ETV7 CHST15 TICAM1 N4BP1 MOB3C RNF149 LILRA3 CSF2RB CD53 ADAM8 NCF1 CD68 TLR8 IL10RB PRKCD PILRA NCF1C ADGRE1 APOBR NAGK SIGLEC5 LILRB3 TNIP1 LILRA6 FGR STX11 NADK NCF2 C19ORF38 GK FCGR3A SIGLEC14 AQP9 HLX CASP5 IFNGR2 NFKB2 TOM1 ELL LACTB SQRDL STK10 ACSL1 HCAR3 MYO9B SLC31A2 PTPRJ NPL AMPD3 AC018755.18 NLRC4 IL6R MERS-CoV 10 Predicted Kinases Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. RIPK1 LYN RPS6KA1 MAP3K11 STK40 HCK RIPK3 PRKCD FGR STK10 MERS-CoV 8 Predicted GPCRs Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a coronavirus, as is SARS-CoV-2, the virus that causes COVID-19 disease. HCAR2 CCR5 CCR1 PTAFR C5AR1 FPR2 ADGRE1 HCAR3 ACE2 93 Literature-Associated Genes from Geneshot GeneRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. CD209 MAPK3 DPP4 SLC6A18 CCL2 CMA1 APLNR ANPEP TMPRSS2 FGF23 TNF SLC6A20 CDH17 MME RHOA ESRRA ACE2 CRYGA ATP6AP2 FABP1 AGTR2 SLC6A19 ZNF274 CLTRN MAPK14 ENPEP CALM3 ADAM17 RELA ACE AGT TMPRSS11D EIF2AK2 AGTR1 UTS2 MAS1 NOS3 CRYGB CLEC4M PI4KB AGTRAP TGFB1 BDKRB1 MBL2 LNPEP MAPK1 AKT1 CD81 SMAD7 LDLR SLC2A4 TGFBR1 MAPT HNF1A SRY FZD1 TNFRSF1A NPPA CSF3 PFN1 SGK1 NOS2 NPPB ADRA2A MIF SIRT1 ADRA2C MMP9 PCSK9 CX3CL1 IRS1 APOE NCF1 BDKRB2 SGK2 HNF1B PRKD1 APELA PRCP GHR REN1 CCN2 AGTR1A LRP2 NPHS1 USF2 ROCK2 NFE2L2 SGK3 ELN TNNI3K MRGPRA2B APLN ACE2 13 Literature-Associated Kinases Genes from Geneshot GeneRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. MAPK3 MAPK14 EIF2AK2 PI4KB MAPK1 AKT1 TGFBR1 SGK1 SGK2 PRKD1 ROCK2 SGK3 TNNI3K ACE2 Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SLC36A1 SLC6A18 SOX14 CYP11B2 CMA1 VCAM1 ANPEP SLC6A20 SLC1A1 THY1 CRYGD MME HSD11B2 ACE2 CACNA1D CRYGA RNPEP TMPRSS4 ATP6AP2 CRYBB2 AGTR2 FCER2 F13B CDX2 FABP2 SLC5A1 SLC6A19 NDRG1 KCNQ1 CLCN6 AP2M1 CRYGC SLC9A3 SERPINE1 SLC15A1 ENPEP HNF4A CRYAA SLC7A9 CTSD ACE NR3C2 AGT TMPRSS11D AGTR1 MAS1 PCK1 CRYBB3 CRYBA2 FBN2 CRYGB AGTRAP EPHX2 FRMD3 RNLS THOP1 FERMT2 TMPRSS13 REN LNPEP GGH NR3C1 RIOK2 VLDLR ITGA2 TNFSF10 RGS2 ADCY2 ECM1 YAP1 ATP1A1 PTGER4 LGALS3BP SLC3A2 ACLY TIMP1 LDLR LGALS1 ZBTB32 TRIP13 LTBP4 CPA3 TPPP LIM2 TGFBR1 EDN1 CTSG LTF ITGA2B ACOX1 CELSR1 SCNN1A WNT4 LRP6 MAF WNT6 MMP8 WNT2 SOX3 SLC8A1 FZD7 HSD11B1 CFB NPPA SELE IFIT3 SLC7A8 KYNU INHBA SLC6A15 SGK1 CRYAB EFEMP1 SLC36A2 ARPC2 ZBTB16 FGB TBX3 EDNRA SPON2 ADRA1A NPPB NPM3 PFN2 ENC1 MMP9 ZDHHC15 MUL1 ASNS ADRB3 ELOVL6 ATP6V0D2 BFSP1 ADRB2 ATF7IP TRIB1 GJA3 ENPP2 ADAM19 STAB2 PRKCD ZDHHC11 PAX2 IGF1 CYP17A1 CELSR2 AKR1D1 ADAM22 TPM1 EPHA2 FGA SGK2 AACS BRD9 NPL PRCP CEP72 SLC7A6 ADD1 CYP11B1 PPARA SLC14A2 SPOCK2 KLK1 CRYBA4 DGKG GRK5 SRPX2 SLC13A3 SOD3 CRYBB1 ACVR2A PTK7 ITIH3 GP1BA TMEM114 ACSM3 LIPC GRK4 SLC12A3 KLKB1 LRPAP1 SLC5A3 PRKCE MTUS1 ATP6V0A4 AKR1C4 GNB3 CYP21A2 EXOC3 CYP11A1 ADRB1 BFSP2 MMP7 ACVR1C CRYBA1 CRYGS IGF2R MTHFR PLEKHF1 ACE2 10 Literature-Associated GPCRs Genes from Geneshot GeneRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. APLNR AGTR2 AGTR1 MAS1 BDKRB1 FZD1 ADRA2A ADRA2C BDKRB2 AGTR1A ACE2 Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. GNA11 F2RL1 MAPK3 DPP4 CUBN SLC6A18 CYP11B2 NOX4 CMA1 APLNR ANPEP TMPRSS2 SPINK1 SI TNF SLC6A20 MME ACE2 ARRB2 RNPEP PF4 ATP6AP2 AGTR2 CDX2 FABP2 SLC6A19 ST14 UBA1 ZNF274 GGT1 ERG CLTRN CTNNB1 NFKB1 IL4 MAPK14 SERPINE1 ENPEP HNF4A CALM3 CALM1 ADAM17 RELA ACE NR3C2 AGT TMPRSS11D AGTR1 TRIM28 MAS1 NOS3 SLC23A1 AFM AGTRAP TGFB1 EGFR BDKRB1 REN LNPEP MAPK1 VLDLR CAMLG ALB TFF3 RGS2 FZD6 PTN NEDD4L ATP1A1 USF1 GRK2 LRP1 SMARCD1 OCRL CTSB AREG KCNE1 LDLR RENBP PPARG CXCL8 CPA3 PTGS2 SLC2A4 PKD2 AVP EDN1 HNF1A WNT1 CYP24A1 SRY WNT4 SOX9 WNT5A ATF3 WNT2 CTNNBIP1 NR5A1 HIF1A SOAT2 UPK3A KNG1 FABP4 NPPA LRP8 PREP SGK1 FSCN1 CBX3 PDX1 AOC3 SLC22A6 NOS2 EDNRA ADRA1A HTR2B NPPB ADRA2A APOM PCBD1 PFN2 ETNK2 ADRA2C MMP9 F13A1 ADRB2 CETP CTSA P2RY6 MRGPRX2 ONECUT1 TWIST1 SCTR APOE ADAM19 MMP2 MAS1L PRKCD BDKRB2 PAX2 CREB1 POMC BSG TIMP3 ARRB1 ATP2A2 APOC1 ACAT1 ERAP1 SGK2 NOX1 TDGF1 HNF1B PRCP REN1 AGTR1A NPHS1 USF2 SGK3 TNNI3K MRGPRA2B APLN ADD1 PPARA KLK1 LIPC GRK4 SLC12A3 KLKB1 LRPAP1 GNB3 ADRB1 NA NPHS2 MRGPRD AGTR1B GCLC OXT HTR2C DRD5 GATA4 NPR1 MCPT4 APOC3 VAMP2 ACTN3 ROBO2 CALCA APOB NEUROD1 GCK SP1 SLC26A3 KCNIP2 PPP1R3A SLC22A8 CD320 KCND3 PITX2 GLP1R ACE2 5 Predicted Ion Channels Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. KCNE1 PKD2 NOX1 KCNIP2 KCND3 ACE2 Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SLC25A31 TEKT3 RGS21 FGF6 GCGR RHPN2P1 TGM6 ERICH4 PRSS42 TMEM202 OR7A17 SPAM1 OR1L3 OR6A2 SLC5A2 SLC13A1 GDF2 TMEM247 UTS2R GIF GHRH SOX14 OR8D2 RNF133 SLC17A4 UGT1A7 OR1G1 TRIM42 FGF23 PDHA2 TAAR1 SAXO1 SLC4A9 TAAR8 SPATA21 HNF4G ACTRT2 PRSS58 OR1A1 FTH1P18 TINAG ALPI PRSS37 SSX7 UROC1 TEX35 OR1Q1 OR4X2 SPACA3 CRX ANKS4B TBC1D3P5 SMIM2IT1 UBE2DNL GABRA6 HMGB4 OR1F2P TBC1D29 SLC22A9 GALR2 WFDC10A OPN1LW TAS2R40 CRYBB2 OR1L4 SULT1C3 UNC93A SLC30A2 GUCA2B SSX5 F13B ADGRD2 FABP2 SLC5A1 TERB1 OR3A3 OR2J3 ZP2 OR1F1 TAS1R2 TBX10 A4GNT GIMD1 TAAR9 AMELY HIGD1AP11 ODF4 FAM71C TRIM64 CRYGC OR13C4 HOXD12 TEX11 AQP2 AKAP4 FAM170A FAM71B OR10H2 TPD52L3 CRYAA SLC7A9 FAM71E2 GPR20 OR1C1 TMEM61 OR1A2 TMC2 TEX13B SPATA19 ACTRT1 TSPYL6 REG1B TEX36 CRYGN PDILT ETDB PRSS50 TREH TEX28 TEX47 ANKRD66 GALR3 GRK7 FAM215A AQP12A TMCO2 TEX12 SMCO2 CRYBB3 CRYBA2 PTH HOXBAS4 CRYGB OR10H1 PGLYRP3 PICSAR AFM SLC5A12 TTTY22 PRSS47 OR1N1 WFDC6 TAS2R39 SEMG2 ODF1 REN SEPT12 UMOD OR8J1 PPY2P AMBN FGF16 FGF3 RSPO4 FGF20 RXFP2 FMO9P HS6ST2AS1 TTTY8 OR5AK4P OPN5 ADAM7 OR7A2P TAS2R1 OR2J2 SCP2D1 TMEM207 SLC12A1 GJA8 SRD5A2 STRA8 PNPLA5 POU1F1 TAS2R41 TRIML1 A1CF SLC12A3 SLC17A1 GSX2 PIH1D3 TSGA13 PYY ADAM30 SPAG11B OFCC1 ADRA2B REG1CP HSD17B3 FOXI1 TTTY4C SPZ1 TRPV5 STMND1 FSHB GHRHR UBE2U TBX22 ALDH1L1AS1 SLC7A13 SLC22A13 ACE2 41 Predicted GPCRs Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. GCGR OR7A17 OR1L3 OR6A2 UTS2R OR8D2 OR1G1 TAAR1 TAAR8 OR1A1 OR1Q1 OR4X2 OR1F2P GALR2 OPN1LW TAS2R40 OR1L4 ADGRD2 OR3A3 OR2J3 OR1F1 TAS1R2 TAAR9 OR13C4 OR10H2 GPR20 OR1C1 OR1A2 GALR3 OR10H1 OR1N1 TAS2R39 OR8J1 RXFP2 OPN5 OR7A2P TAS2R1 OR2J2 TAS2R41 ADRA2B GHRHR ACE2 Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SLC36A1 LCT CUBN SLC6A18 SOX14 CYP11B2 NOX4 FAM71D CMA1 APLNR ANPEP STX3 SLC6A20 SLC1A1 CRYGD MME ANKS4B ESRRA SLC7A7 ACE2 CACNA1D YWHAG CRYGA RNPEP TMPRSS4 ATP6AP2 CRYBB2 AGTR2 XPNPEP2 SLC5A1 SLC6A19 NDRG1 FURIN LAP3 FRMPD4 CLCN6 CLTRN CRYGC SLC9A3 AMN AQP2 SLC15A1 ENPEP HNF4A CRYAA SLC7A9 ACE NR3C2 AGT AGTR1 TRIM28 MAS1 CRYBB3 CRYBA2 AGTRAP RNLS THOP1 TMPRSS13 REN LNPEP PROZ A2ML1 KLK11 FZD6 MBNL2 TMPRSS11E ATP1A1 USF1 DPP7 ARAP1 SLC1A5 LDLR RENBP CTSZ SNAPIN TRIP13 CPA3 TPPP LIM2 KLK4 CTSG CELSR1 SCNN1A WNT4 LRP6 FZD3 LEF1 RAB4A WNT6 FZD10 FZD8 SLC9A3R2 SOX3 MESP1 SOX12 FZD7 CLCN5 FZD9 KNG1 IL36G SLC7A8 IL1R2 PREP NPRL3 EPPIN-WFDC6 SLC3A1 SLC6A15 COX6A2 SGK1 CRYAB HMGCS1 SLC36A2 C1QBP RAB11A PDX1 SEZ6L2 SLC22A11 HAVCR1 VRK1 LRP11 SOAT1 TNP1 ZDHHC15 CDH6 ZBED8 PCDH9 FXYD2 CEACAM1 GJA3 ONECUT1 ADAM19 SPRR2E SLC6A17 CORIN ZDHHC11 PAX2 CELSR2 AKR1D1 STX7 STX4 PCDHA4 XYLT2 ZNF41 SGK2 TMEM129 BRD9 FHOD1 PRCP CEP72 SLC7A6 CYP11B1 SPOCK2 KLK1 CRYBA4 GRK5 SLC13A3 CRYBB1 TMEM114 GRK4 KLKB1 SLC5A3 MTUS1 AKR1C4 GNB3 EXOC3 ADRB1 BFSP2 CRYBA1 CRYGS IGF2R MRGPRD ZNF699 NKX6-1 KLK13 BSND CPM SLC1A6 SYDE2 KLF8 DEFB126 NFAM1 SREBF2 ZBTB14 CDH15 ZBED5 NPEPPS ADCY1 KLK14 ZBED4 DNPEP ZNF674 CLPTM1L ATP1A4 ZNF81 AGXT2 CPA4 INSIG2 LRP1B GAGE12J HTR1E ACE2 Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. MAOA GNA11 MOGAT2 TMEM82 TM4SF20 SLC10A2 MISP FAM3B ERICH4 CES2 SEC16B EPS8L3 NAALADL1 NR1I2 FCGRT SLC13A1 CPO DPP4 CAPN5 CUBN CYP4F12 GLYCTK PBLD TM6SF2 SLC17A4 TMEM37 ANPEP CYP3A4 PRAP1 ADAMDEC1 MALL BTNL3 DEFA5 SI TMIGD1 DGAT1 C1ORF115 AADAC SLC1A1 CDH17 HNF4G PCK2 CREB3L3 OTC GUCA2A CEACAM20 UGT2A3 RBP2 NR1H4 ANKS4B MYO1A MALRD1 SLC13A2 DPEP1 HSD11B2 ACE2 PPP1R14D TRIM15 MYO15B SMIM24 CYP2J2 VIL1 CYP4F2 GPT MTTP SEPP1 GBA3 FABP1 SLC22A18 PDZD3 PRR15L GUCA2B ENTPD8 XPNPEP2 ISX KHK ACSL5 TUBAL3 CDX2 REG3A FABP2 SLC5A1 SDCBP2 SLC6A19 CRYL1 VILL CDHR5 GPA33 SLC46A3 MEP1B LRRC66 LRRC19 NLRP6 SLC9A3 CDX1 AMN TMEM54 CLDN15 SLC28A1 SLC15A1 ENPEP HNF4A SLC7A9 ACAA1 BTNL8 TCN2 CLRN3 PLS1 BAIAP2L2 HEPH DEFA6 MTMR11 PHGR1 APOA4 DMBT1 REG4 CYP2C18 FABP6 TST ACE GIPC2 TREH TM4SF5 TMEM176A CHP2 TSPAN8 PTPRH SLC5A9 CLCA1 USH1C MUC3A TDP2 LGALS4 PCK1 MUC17 MGAM PEPD DHRS11 ADGRG7 UNC5CL MEP1A PLB1 HHLA2 ITLN2 SLC23A1 KCNJ13 SULT1A2 ALDOB CCL25 KRT20 SLC5A12 AKR7A3 C17ORF78 TTC38 EPHX2 AGPAT2 GUCY2C FLJ22763 C11ORF86 ACADS HKDC1 TKFC MS4A10 MUC13 FCGBP ENTPD5 CDHR2 UGT2B17 TMEM253 SLC39A5 EPCAM CLDN7 ABCG8 C1ORF106 B3GALT5 TMEM45B BCL2L15 SLC3A1 DDC TMEM176B IHH SLC28A2 SLC51A CDC42EP5 SMPD3 KLC4 FUT3 CHDH SLC51B SOWAHA MUC2 UGT1A10 CCL15-CCL14 FUT6 GDA G6PC ZG16 SEMA4G GGT6 NAT2 ACE2 302 Literature-Associated Genes from Geneshot AutoRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SLC36A1 GCGR IL2 IL6 SYVN1 DPP4 SLC6A18 SOX14 POU5F1 CCL2 CYP11B2 NOX4 CMA1 CD34 APLNR ANPEP STAT3 TMPRSS2 FGF23 RPL12 COMT TNF SLC6A20 CXCL5 CDH17 PKP2 SCAP MME RHOA CXCL10 HSD11B2 ACE2 TLR4 SWI5 CXCL16 CRYGA CYP2J2 RNPEP CPA2 ATP6AP2 AGTR2 ANXA2 IGSF3 SLC5A1 SLC6A19 FURIN EPS15 KCNQ1 LAP3 COL4A3 ZNF274 ESR1 JAK2 GGT1 CLCN6 EHBP1 SMAD3 CTNNB1 NFKB1 HMOX1 SLC15A1 ENPEP HNF4A CALM3 PHB2 MID2 DNMT1 REG4 CTSD ATP1B1 ADAM17 TMPRSS11A CRK ACE NR3C2 AGT AGTR1 UTS2 MAS1 LGALS4 ITM2A PHB WFS1 NOS3 PLB1 CRYGB CLEC4M KRT20 AGTRAP TGFB1 NUP85 EPHX2 SRC EGFR MOB2 RNLS THOP1 APP REN LNPEP CASP3 PLP2 IL10 CDK2 NR3C1 KDR CAV1 YAP1 SOX2 SLPI LCN2 BAX ATP1A1 CD81 CYBA SMAD7 TIMP1 LDLR CDK5 IGFBP2 CDC6 BIRC5 SMTN IL18 SNAPIN GAPDH CCNB1 CDC20 NTSR1 ANG ESR2 CPA3 PTGS2 SLC2A4 MYC COL1A1 MMP1 TGFBR1 CDH1 ACTB BDNF HNF1A CTSG MITF INS FOXM1 MTOR SREBF1 SCNN1A SRY FZD1 WNT4 EREG MMP8 SOX3 TNFRSF11B HIF1A CASR MEF2A TNFRSF1A HSD11B1 H2AFX KNG1 PON1 ADIPOQ CCK CYP1A1 NPPA CYBB SOCS3 NAMPT SCN1A PFN1 FOS SGK1 DUSP1 ICAM1 NFKBIA AGER VEGFA UCP1 LYZ CHIA ZBTB16 SOD1 CSF1R GPX4 NOS2 OLFM4 AQP4 FOSB MMP10 MIF HMGB1 ATG5 RPL32 SIRT1 CORT AKR1B10 MMP9 PTS MFAP4 CASP1 PIK3CG PCSK9 SMURF2 CEACAM1 CX3CL1 NPY1R SOD2 IRS1 BTC PTGS1 MPO CASP8 ROCK1 ADAM10 CD44 GPRC6A SIRT4 IGF2 APOE CXCL14 MMP2 NCF1 CD68 PRDX2 CRP IGF1 EIF2AK4 KIT CYP17A1 BACE1 POMC MRAS EEA1 TNFSF11 TERT PARP1 SPRY1 XBP1 TNFRSF1B TIMP3 AKR1D1 MMP14 EGF ATP2A2 ADAM22 SPP1 IRAK3 CDC42 CLN3 MAP3K3 NOX1 CDR1 SMAD2 NLRP3 PRKD1 PRCP GHR USF2 ROCK2 NFE2L2 ELN CYP11B1 KLK1 SOD3 SLC12A3 MTUS1 AKR1C4 CYP21A2 CYP11A1 IGF2R MTHFR PITX2 BSND SREBF2 KEAP1 SIRT3 EPO GDNF SRF ABI3 KRT12 FXN PER2 HDAC4 NOS1 FGF21 BMX ADCYAP1 GAS7 ECE1 NPAS2 GDF9 CDC34 HCN4 TRPM7 MPDZ CRH SIRT6 CPA1 ACE2 19 Literature-Associated Kinases Genes from Geneshot AutoRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. JAK2 SRC EGFR CDK2 KDR CDK5 TGFBR1 MTOR SGK1 CSF1R PIK3CG ROCK1 EIF2AK4 KIT IRAK3 MAP3K3 PRKD1 ROCK2 BMX ACE2 10 Literature-Associated GPCRs Genes from Geneshot AutoRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. GCGR APLNR AGTR2 AGTR1 MAS1 NTSR1 FZD1 CASR NPY1R GPRC6A ACE2 8 Literature-Associated Ion Channels Genes from Geneshot AutoRIF ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. KCNQ1 CLCN6 SCNN1A CYBB SCN1A NOX1 HCN4 TRPM7 ACE2 Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SLC36A1 RSRC2 SLC6A18 CYP11B2 NOX4 CMA1 VCAM1 ANPEP SLC6A20 CRYGD MME ESRRA HSD11B2 ACE2 RNPEP ATP6AP2 CRYBB2 AGTR2 COL4A1 KLK3 ANXA2 IGSF3 SLC5A1 SLC6A19 NDRG1 EPS15 ESR1 CLCN6 IFNG CRYGC SLC9A3 SERPINE1 FLT1 SLC15A1 ENPEP CRYAA CALM3 SLC7A9 PSMC6 CTSD ACE NR3C2 AGT TMPRSS11D FBN1 AGTR1 MAS1 ITM2A CRYBB3 WFS1 CRYBA2 FBN2 AGTRAP HS2ST1 EPHX2 RNLS THOP1 KLK2 FERMT2 REN LNPEP RAB10 NR3C1 ECM1 CFH SLPI PLA2G7 ATP1A1 PLOD1 SMARCD1 ACLY TIMP1 LGALS1 TIMP4 ZBTB32 GAPDH MMP19 TRIP13 PTGFRN NCAPG LTBP4 CPA3 LIM2 TGFBR1 EDN1 CTSG ITGA2B ACOX1 SCNN1A SPDEF SRY MAF MMP8 SOX3 SLC8A1 HSD11B1 CFB KNG1 CTSS NPPA IFIT3 SLC7A8 IFIT2 COL3A1 INHBA PLAU SLC6A15 COX6A2 SGK1 CRYAB TGM2 HPGD EFEMP1 SLC36A2 RPL35 ZBTB16 APOH FGB DAPL1 EDNRA COL21A1 SPON2 NPPB MAGT1 MMP10 HSP90B1 SEH1L NPM3 ETNK2 MUL1 ALDH3A1 BFSP1 SOD2 ATF7IP GJA3 ADAM19 STAB2 C4B CORIN PRKCD ZDHHC11 PAX2 IGF1 SOX5 CYP17A1 CTSF AKR1D1 FBLN1 IRAK3 EPHA2 SGK2 AACS BRD9 PRCP CEP72 ADD1 CYP11B1 PPARA SPOCK2 KLK1 CRYBA4 DGKG SRPX2 SLC13A3 SOD3 CRYBB1 ITIH3 GP1BA TMEM114 GRK4 SLC12A3 PRKCE MTUS1 AKR1C4 GNB3 CYP21A2 EXOC3 CYP11A1 ADRB1 BFSP2 CRYBA1 CRYGS IGF2R MTHFR PLEKHF1 LRP1B FGF21 TGFA ECEL1 SCNN1B SLC9A4 LRRN1 KCNJ5 OSTM1 AVPR1A CMBL LCORL ARHGAP5 RAB23 CEL ACE2 9 Predicted Kinases Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. FLT1 TGFBR1 SGK1 PRKCD IRAK3 EPHA2 SGK2 GRK4 PRKCE ACE2 Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. GNA11 F2RL1 EEF1A1 MAPK3 DPP4 SLC6A18 CCL2 CYP11B2 NOX4 CMA1 APLNR ANPEP CTSL TNF SLC6A20 IRF3 MME COL4A5 HSD11B2 ACE2 ARRB2 CRYGA RNPEP ATP6AP2 AGTR2 COL4A1 KLK3 FABP2 SLC6A19 ST14 UBA1 ERG CLTRN IL4 MAPK14 SERPINE1 ENPEP CALM1 ADAM17 ACE NR3C2 AGT CANX TMPRSS11D FBN1 AGTR1 UTS2 MAS1 PLAT NOS3 CRYGB AGTRAP TGFB1 EGFR BDKRB1 REN LNPEP MAPK1 NR3C1 CAMLG CAV1 TPSAB1 TPSB2 CFTR RGS2 PTN ATP1A1 USF1 GRK2 CYBA SMARCD1 NCSTN NLN CTSB RENBP PPARG CCR2 CPA3 A2M GATA3 SLC2A4 COL1A1 TGFBR1 NRDC EDN1 CTSG CYP24A1 SRY WNT10A LAMP1 CTSC CCR5 NPPA SERPINA3 CPB1 TXN VEGFA ITM2C TAGLN PPP1CA VIM ZBTB16 STK38 CD9 AOC3 ADAMTS10 ADRA1A NPPB MUC5AC HSP90B1 SLC25A5 PPP3CA ETNK2 ADRA2C MMP9 MRPS11 ADRB2 TNRC6B IGF1R RNF145 NPY1R FUT4 CTSA P2RY6 MRGPRX2 APOE ADAM19 ADAM12 MMP2 DPYS NCF1 MAS1L PRKG1 HS3ST3B1 BDKRB2 SFR1 PIK3CD PAX2 CREB1 BACE1 POMC GNAQ PIAS1 TIMP3 ARRB1 APOC1 CD33 ACAT1 ERAP1 PTER PGPEP1 NOX1 SMAD2 HNF1B PRCP REN1 AGTR1A NPHS1 USF2 ELN TNNI3K MRGPRA2B APLN ADD1 CYP11B1 GP1BA GRK4 GNB3 ADRB1 MTHFR NPHS2 MRGPRD AGTR1B HTR2C NPR1 MCPT4 ACTN3 SREBF2 NPEPPS HDAC4 ECE1 CPA1 TGFA EFEMP2 NUP160 CELA3A NAF1 ATP4B CRYGE STK38L MEGF9 SLC6A20B JAZF1 COL4A3BP RLN2 CELA2A LMTK2 STH DUOX1 FAM3C ACE2 15 Predicted Kinases Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. MAPK3 MAPK14 EGFR MAPK1 GRK2 TGFBR1 STK38 IGF1R PRKG1 PIK3CD TNNI3K GRK4 NPR1 STK38L LMTK2 ACE2 Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. ZP4 SLC25A31 TEKT3 OR6B3 RGS21 FGF6 GCGR RHPN2P1 GPR151 TGM6 SNARC5 PRAC2 ERICH4 SPATA31E1 PRSS42 TMEM202 OR7A17 SPAM1 OR1L3 OR6A2 SYNGR4 SLC5A2 PRSS55 SLC13A1 GDF2 TMEM247 UTS2R GIF GHRH OR8D2 RNF133 TRBV102 WFIKKN1 OR2W1 TGM4 UGT1A7 H1FOO OR1G1 OR1I1 TRIM42 FGF23 ZNF252PAS1 PDHA2 TAAR1 SAXO1 SNARA8 TMEM239 SLC4A9 TAAR8 SPATA21 ACTRT2 PRSS58 OR1A1 CRYGD PTCRA FTH1P18 TINAG ALPI PRSS37 SSX7 UROC1 TEX35 OR1Q1 OR4X2 OR10A4 SPACA3 CRX AGRP ANKS4B TBC1D3P5 SMIM2IT1 UBE2DNL GABRA6 HMGB4 OR1F2P TBC1D29 SLC16A8 SLC25A41 RTP2 SLC22A9 GALR2 SNARA13 OR13J1 WFDC10A OPN1LW OR1N2 TP53AIP1 TAS2R40 PGLYRP4 OR3A2 CRYBB2 OR1L4 SULT1C3 UNC93A SLC30A2 GUCA2B SNARI SSX5 F13B ADGRD2 REG3A TERB1 OR3A3 OR2J3 OR6Y1 ZP2 SLFNL1 OR1F1 TAS1R2 PGC TBX10 A4GNT RPS2P52 TAAR9 AMELY HIGD1AP11 ODF4 PSG6 FAM71C TRIM64 CRYGC OR13C4 HOXD12 TAAR2 TEX11 AQP2 AKAP4 FAM170A OR10G3 FAM71B OR10H2 TPD52L3 CRYAA SLC7A9 FAM71E2 GPR20 TREML3P OR1C1 PDZD9 TMEM61 OR1A2 TMC2 TEX13B RSPH6A SPATA19 ACTRT1 TRIM40 TSPYL6 REG1B TMEM270 GPR142 OR10A6 TEX36 CRYGN PDILT ETDB PRSS50 TREH TEX28 OR5AK2 TEX47 ANKRD66 GALR3 GRK7 FAM215A FBXW12 OR6C3 PTGER1 AQP12A TMCO2 TEX12 POM121L4P SMCO2 CRYBB3 CRYBA2 PTH ZNF575 HOXBAS4 CRYGB OR10H1 PGLYRP3 FAM221B TAS2R38 PICSAR AFM TTTY22 PRSS47 OR1N1 WFDC6 TAS2R39 SEMG2 OR1S2 ODF1 SEPT12 SPEM1 UMOD OR51B6 OR8J1 WFDC5 PPY2P ACE2 52 Predicted GPCRs Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. OR6B3 GCGR GPR151 OR7A17 OR1L3 OR6A2 UTS2R OR8D2 OR2W1 OR1G1 OR1I1 TAAR1 TAAR8 OR1A1 OR1Q1 OR4X2 OR10A4 OR1F2P GALR2 OR13J1 OPN1LW OR1N2 TAS2R40 OR3A2 OR1L4 ADGRD2 OR3A3 OR2J3 OR6Y1 OR1F1 TAS1R2 TAAR9 OR13C4 TAAR2 OR10G3 OR10H2 GPR20 OR1C1 OR1A2 GPR142 OR10A6 OR5AK2 GALR3 OR6C3 PTGER1 OR10H1 TAS2R38 OR1N1 TAS2R39 OR1S2 OR51B6 OR8J1 ACE2 7 Predicted Dark GPCRs Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. GPR151 TAAR8 ADGRD2 TAAR9 TAAR2 GPR20 GPR142 ACE2 Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SLC36A1 RSRC2 IGSF8 UTS2R SLC6A18 SOX14 CYP11B2 NOX4 CMA1 ANPEP SLC6A20 CRYGD MME HSD11B2 ACE2 CACNA1D SWI5 RNPEP ANXA3 ATP6AP2 CRYBB2 AGTR2 XPNPEP2 IGSF3 SLC6A19 EPS15 LAP3 ZNF274 CLCN6 CLTRN CRYGC SLC9A3 FYCO1 SLC15A1 ENPEP CRYAA SLC7A9 ACE NR3C2 AGT AGTR1 TRIM28 MAS1 HERPUD1 ITM2A CRYBB3 CRYBA2 NPLOC4 AGTRAP EPHX2 RNLS THOP1 KLK2 REN LNPEP RAB10 GGH DDAH2 ADCY2 DUOX2 SLPI ATP1A1 DPP7 CYBA PLOD1 ARAP1 SLC1A5 NLN RENBP TRIP13 CPA3 TPPP LIM2 NRDC CTSG SCNN1A RAB4A SOX3 CLCN5 HSD11B1 LRCH4 GDF3 HMGB2 CDH26 NPPA SLC7A8 PREP NPRL3 EPPIN-WFDC6 SLC3A1 SLC6A15 COX6A2 SGK1 CRYAB SLC36A2 CTSH BLMH TUBB2A CREB5 AKR1E2 ZNF436 NPPB DLX4 BHLHE40 MAGT1 MMP10 SEH1L AFTPH INSIG1 SQLE PCDH9 SLC1A4 MTF2 RAB29 FLI1 GJA3 DPEP2 ADAM19 SLC6A17 CDC14A ZDHHC11 SOX5 CYP17A1 MRAS EEA1 AKR1D1 YIPF1 ZNF569 ZNF629 ZNF763 ZNF44 ZNF501 IRAK3 CLCN7 XPNPEP3 XYLT2 ZNF587 ERAP1 SGK2 PGPEP1 RNPEPL1 NOX1 BRD9 SMPD4 ELF5 PRCP CEP72 ADD1 CYP11B1 SPOCK2 KLK1 CRYBA4 SLC13A3 CRYBB1 TMEM114 GRK4 MTUS1 AKR1C4 GNB3 CYP21A2 CYP11A1 BFSP2 CRYBA1 CRYGS IGF2R MRGPRD ZNF699 CPM SYDE2 SREBF2 NPEPPS ADCY1 DNPEP CLPTM1L ATP1A4 AGXT2 CPA4 LRP1B CPA1 ECEL1 SCNN1B KCNJ5 LCORL RAB23 CELA3A LMTK2 DUOX1 YIPF2 CTRB1 GTF3A CLCN2 TRMT1L DPEP3 GANC ZNF3 BBS7 DGKI FOXG1 RREB1 POU3F4 ACE2 5 Predicted Kinases Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. SGK1 IRAK3 SGK2 GRK4 LMTK2 ACE2 Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. MAOA ANO9 SLC36A1 GNA11 MOGAT2 TMEM82 GAK TM4SF20 SLC10A2 MISP FAM3B ERICH4 CES2 NBL1 SEC16B EPS8L3 NAALADL1 NR1I2 FCGRT MAPK3 SLC13A1 CPO DPP4 CAPN5 CUBN CYP4F12 GLYCTK PBLD TM6SF2 SLC17A4 TMEM37 MVP ANPEP CYP3A4 CTDSP1 PRAP1 ADAMDEC1 MALL VDR FBXW5 BTNL3 DEFA5 SI TMIGD1 DGAT1 C1ORF115 AADAC SLC1A1 CDH17 HNF4G PCK2 CREB3L3 OTC GUCA2A CEACAM20 UGT2A3 RBP2 NR1H4 MYO1A MALRD1 SLC13A2 DPEP1 ESRRA ZZEF1 MYO1D HSD11B2 SLC7A7 ACE2 PPP1R14D TRIM15 MYO15B CYP2J2 VIL1 CYP4F2 GPT MTTP SEPP1 TMBIM1 GBA3 PFKL FABP1 SLC22A18 PDZD3 PRR15L GUCA2B ENTPD8 XPNPEP2 ISX KHK ACSL5 TUBAL3 CDX2 REG3A FABP2 SLC5A1 SDCBP2 SLC6A19 TPRN CRYL1 ST14 VILL ZBTB7B KCNQ1 CDHR5 VIPR1 GPA33 GGT1 SLC46A3 MEP1B LRRC66 LRRC19 FAM109A NLRP6 SLC9A3 CDX1 AMN TMEM54 CLDN15 SLC28A1 SLC15A1 ENPEP HNF4A SLC7A9 ACAA1 BTNL8 TCN2 NAGS PLCB3 CLRN3 PLS1 BAIAP2L2 HEPH DEFA6 KIAA2013 MTMR11 PHGR1 APOA4 DMBT1 REG4 NUCB1 CYP2C18 FABP6 TST ACE GIPC2 TREH ACADVL TMEM176A CHP2 ABCG2 TSPAN8 MGAT4B CNDP2 PTPRH RETSAT EPS8L2 SLC5A9 ACY1 CLCA1 USH1C MUC3A TDP2 LGALS4 PCK1 MUC17 MGAM PEPD DHRS11 ADGRG7 UNC5CL MEP1A PLB1 HHLA2 ITLN2 SLC23A1 KCNJ13 SULT1A2 ALDOB CCL25 KRT20 SLC5A12 AKR7A3 C17ORF78 TTC38 EPHX2 AGPAT2 GUCY2C FLJ22763 C11ORF86 FBP1 ACADS TKFC MUC13 REEP6 FCGBP ENTPD5 CDHR2 UGT2B17 TMEM253 SLC39A5 ACE2 6 Predicted Kinases Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity ACE2 has been shown to be a co-receptor for SARS-CoV-2 viral entry, with increasing evidence that it has an extended role in COVID-19 pathogenesis. GAK MAPK3 PCK2 PFKL KHK GUCY2C TMPRSS2 161 Literature-Associated Genes from Geneshot GeneRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR F2RL1 CANT1 NBL1 IL6 MAPK3 DPP4 FAM71D TGM4 SEC14L1 TMPRSS2 CTSL PTEN SPOP SQSTM1 VDR SPINK1 TMPRSS3 SLC45A3 KPNA2 DDX5 VHL MPP5 LSAMP ESRRA ACE2 CACNA1D TLR4 TMPRSS4 ELAVL1 KLK3 ANXA2 NDRG1 ETV1 ST14 FURIN BRAF ETV4 TDRD1 ESR1 NCL HOOK3 ERG FLT1 CRISP3 ATM TMPRSS7 ADAM17 RELA TMPRSS11A TRIM25 PDE4D TMPRSS11D WASF1 ERBB2 FOXA1 NEDD8 BRD4 ELK4 HSPBAP1 ETV5 EGFR KLK2 TMPRSS13 GGH MX1 CHD1 MAPK1 TFF3 ITGA2 ZEB2 AQP5 KLK11 FOXP2 TP63 ZEB1 PSCA TMPRSS11E BANF1 SMARCD1 NFE2L1 EZH2 CTSB ADAM15 HGF LGALS3 IDH1 PRDX3 AKR1C3 GATA3 ATR MYC NOTCH1 CDH1 WNT1 SPINT1 CYP24A1 AR MTOR MLPH SCNN1A GRHL2 LEF1 SOX9 FZD4 CREBBP ERF DAXX FOSL1 ETS1 GSTP1 VEGFA CD9 PTGER2 PRDX4 HDAC1 APEX1 MMP9 ETV6 CEP131 IGF1R XRCC4 PRSS3 ILK FLI1 SP5 HOXB13 CDK9 KDM1A BSG CXCR4 TERT PARP1 MAP3K7 SPP1 TBXA2R CITED2 NBN RAF1 PLXNA2 ERCC1 COP1 KAT2B PRSS8 NFE2L2 FAM13C LIG4 PRMT5 SENP1 MAGI2 CHD8 CATSPERZ SRA1 TMPRSS15 CTAG1B CDKN2A EWSR1 E2F3 USP9X PLXNB1 TMPRSS2 161 Literature-Associated Genes from Geneshot GeneRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR F2RL1 CANT1 NBL1 IL6 MAPK3 DPP4 FAM71D TGM4 SEC14L1 TMPRSS2 CTSL PTEN SPOP SQSTM1 VDR SPINK1 TMPRSS3 SLC45A3 KPNA2 DDX5 VHL MPP5 LSAMP ESRRA ACE2 CACNA1D TLR4 TMPRSS4 ELAVL1 KLK3 ANXA2 NDRG1 ETV1 ST14 FURIN BRAF ETV4 TDRD1 ESR1 NCL HOOK3 ERG FLT1 CRISP3 ATM TMPRSS7 ADAM17 RELA TMPRSS11A TRIM25 PDE4D TMPRSS11D WASF1 ERBB2 FOXA1 NEDD8 BRD4 ELK4 HSPBAP1 ETV5 EGFR KLK2 TMPRSS13 GGH MX1 CHD1 MAPK1 TFF3 ITGA2 ZEB2 AQP5 KLK11 FOXP2 TP63 ZEB1 PSCA TMPRSS11E BANF1 SMARCD1 NFE2L1 EZH2 CTSB ADAM15 HGF LGALS3 IDH1 PRDX3 AKR1C3 GATA3 ATR MYC NOTCH1 CDH1 WNT1 SPINT1 CYP24A1 AR MTOR MLPH SCNN1A GRHL2 LEF1 SOX9 FZD4 CREBBP ERF DAXX FOSL1 ETS1 GSTP1 VEGFA CD9 PTGER2 PRDX4 HDAC1 APEX1 MMP9 ETV6 CEP131 IGF1R XRCC4 PRSS3 ILK FLI1 SP5 HOXB13 CDK9 KDM1A BSG CXCR4 TERT PARP1 MAP3K7 SPP1 TBXA2R CITED2 NBN RAF1 PLXNA2 ERCC1 COP1 KAT2B PRSS8 NFE2L2 FAM13C LIG4 PRMT5 SENP1 MAGI2 CHD8 CATSPERZ SRA1 TMPRSS15 CTAG1B CDKN2A EWSR1 E2F3 USP9X PLXNB1 TMPRSS2 14 Literature-Associated Kinases Genes from Geneshot GeneRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). MAPK3 BRAF FLT1 ATM ERBB2 EGFR MAPK1 ATR MTOR IGF1R ILK CDK9 MAP3K7 RAF1 TMPRSS2 5 Literature-Associated GPCRs Genes from Geneshot GeneRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). F2RL1 FZD4 PTGER2 CXCR4 TBXA2R TMPRSS2 Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR CANT1 NBL1 FKBP10 POU5F1 FAM71D ANPEP TGM4 TMPRSS2 PTEN SPOP SPINK1 SLC45A3 DDX5 CDH17 MME ESRRA CACNA1D TMPRSS4 VIL1 TMBIM1 KLK3 CDX2 NDRG1 TMPRSS5 ETV1 FURIN ETV4 TDRD1 ESR1 PMEPA1 ERG FRMD6 CRISP3 TMPRSS7 TMPRSS11D FOXA1 PABPC1 ELK4 PES1 ETV5 SEMG2 KLK2 TMPRSS13 GGH CHD1 HPN HOXC6 TFF3 CDK2AP1 ITGA2 KRT7 ZNF532 KRT4 ZEB2 FGFR2 PATJ SERPINB5 KLK11 ELF3 ZEB1 CKS2 KRT19 INPP4B TFF1 SPINK5 ESRP1 PSCA PLA2G7 CCND1 SRD5A1 EZH2 CCNB2 UBE2C HSD17B4 HMMR AURKA BUB1 CDKN2B ANLN MKI67 GATA3 MYC ZNF185 KLK4 MMP11 SPINT2 SPINT1 LTF CDH3 ZNF217 SPDEF MST1R SPARCL1 RHOU CLU SFRP4 KLK5 CTRC USP9Y CREBBP PDLIM5 TMEM45B TNFAIP6 DDX4 PLAU RASGRP3 HPGD SERPINE2 RBM3 NTRK3 CCND2 SPON2 HMGB3 PTTG1 SMARCA5 HOXB7 KPNA3 AGPAT5 SNX9 FAM129A PTPRD PCDH9 ETV6 BCL11A TFF2 SPIB ATP6V0D2 HLA-DMB PRSS1 TFPI2 HNRNPA2B1 CHD4 SEMG1 ETS2 SERPINA1 ARHGEF3 KLK7 BCAR3 CDH13 KLK6 ETV3 TAL1 OR51E2 CORIN HOXB13 ANGPT2 CAMSAP1 CDK6 CA12 MAP3K7 TPM1 CADM2 RCBTB2 RASSF1 ARID1B KLK10 ELF5 PRSS8 KLK1 ATP6V0A4 MMP7 SP1 KLK13 KLK14 MAGI2 NDUFAF6 ACSM1 KDM3A MUC7 SETD7 GREB1 ARID1A AZGP1 KDM4A SEMA6A FOXP1 NCOR1 SALL4 OVGP1 CER1 KDM6A CABYR KLK12 NCOA2 TEX15 GOLM1 DLX1 CALN1 PLXNA1 PARD3 ELAC2 GLYATL2 KLK8 KCNH8 SUFU UBTF STEAP2 KLK15 TMPRSS2 7 Predicted Kinases Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). FGFR2 AURKA BUB1 MST1R NTRK3 CDK6 MAP3K7 TMPRSS2 Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR F2RL1 NBL1 POU5F1 FAM71D TGM4 EGR1 TMPRSS2 PTEN SPINK1 TMPRSS3 SLC45A3 CDH17 RCHY1 MPP5 ESRRA CCND3 EP300 TMPRSS4 KLK3 NDRG1 ETV1 ST14 RUNX1 ETV4 ESR1 ERG CTNNB1 MAPK14 CRISP3 TMPRSS7 TP53 ADAM17 STAT1 TMPRSS11D ERBB2 FYN ELK4 ETV5 EGFR KLK2 TMPRSS13 USP7 CDK2 CHD1 HPN TFF3 MCF2L ITGA2 MSMB HES1 KLK11 ELF3 ITGA10 TP63 TMPRSS11E CCND1 BANF1 RNASEL SMARCD1 EZH2 CEBPA CTSB MSR1 CDK1 E2F1 HGF MKI67 CXCL8 AKR1C3 GATA3 KLF2 CDKN1A MYC KLF10 MMP1 SPINT2 WNT1 SPINT1 AR NCOA3 RARG SPDEF MST1R LEF1 SOX9 KLK5 WNT3A TCF7 SLC45A4 CREBBP GFI1 DAXX PIM1 PLAU SNAI2 IRF2 ETS1 KLF4 CDH5 FOS EGFL7 GATA2 JUN SEMA3C SERPINE2 SERPINB9 PSAP AHRR CCND2 IKZF1 MUC5AC CTBP2 MMP9 SRD5A2 MST1 ETV6 TDRD7 CEP131 RCOR2 DYNC1LI1 PRSS2 TFPI2 ETS2 ZNF649 PRSS3 SERPINA1 CDKN1B NONO KLK7 HEYL FLI1 TWIST1 KLK6 TAL1 OR51E2 HOXB13 GDF5 CTCF SP8 RET KDM1A CYP17A1 MMP14 MAPKAPK2 TRP53 EPPIN COPS6 CMTM3 SMARCB1 SUV39H2 KLK10 ELK3 COP1 PRSS8 MMP7 SP1 KLK13 KLK14 SRF CTAG1B CDKN2A EWSR1 PLXNB1 KDM4A FOXP1 NCOR1 KLK15 SSRP1 KMT2A HIST1H3A KLLN CCAR2 TDRD6 ELK1 NT5C3B NANOG PTPN11 UBTFL1 KRT34 MRTFA WWTR1 GABPA TRIM24 USP28 SLC22A3 PLXNA3 RAB27A ACACA LPP ADGRE3 PIAS4 LIN7B MAGI1 CACUL1 SVS1 1810009J06RIK ID4 TMPRSS2 11 Predicted Kinases Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). MAPK14 ERBB2 FYN EGFR CDK2 RNASEL CDK1 MST1R PIM1 RET MAPKAPK2 TMPRSS2 Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). TGM6 SPAM1 OR6A2 PRSS55 RNF133 FAM71D SLC17A4 UGT1A7 TRIM42 TAAR1 TINAG UBE2DNL PPP1R14D OR13J1 PGLYRP4 F13B ADGRD2 SLC5A1 ZP2 TAS1R2 TEX11 SLC28A1 ACTRT1 TMPRSS7 GPR142 TEX36 PDILT TREH TMPRSS11D ST6GALNAC1 PTH FRMD1 PGLYRP3 PRSS47 OR8J1 WFDC5 FAM83B TMPRSS11E WDR72 GLYATL1 ST13P20 FTLP14 RN7SL12P ADGRF4 GJB5 SLC5A8 ODAM SLC45A2 GCM1 OR10V1 FMO9P TCP10 TRIM64C OR13C8 OR5AK4P OR7E91P ADAM7 AGBL1AS1 OR5F1 OR8S1 FIGLA UGT2A2 SSX4 GPC6AS2 RSU1P2 OR4E2 SPINK14 SCP2D1 ZNF645 TMEM225 TMEM207 PRKACG TRPV6 SOWAHB UPK2 SMIM23 TBC1D21 FSHR ZNRF4 PNPLA5 ZSWIM2 CPA5 ANKRD31 APOBEC4 ZC2HC1B TRIML1 SLC22A24 SLC28A3 ZSCAN4 GPRC6A PRSS38 RNF148 A1CF ANKRD7 SDR9C7 SMCP PPP3R2 PROP1 SERPINB12 FAM3D SLC17A1 HSD17B3 STMND1 UBE2U TBX22 AGXT2 FUT6 CPA1 ADAM18 SPERT PGBD4P8 SLC30A8 ACTBP13 SNORD168 TOPAZ1 ADCY10 RFX6 GPC5AS1 SNORD169 VWA2 SLC22A2 PLCZ1 GTF2A1L RAG2 TFDP3 WEE2 ACP7 OR5AU1 TRIM60 TRIM50 TMC1 SSX4B TBPL2 SNORD137 FAM9B RNF183 SPINK13 TMPRSS11F CPA6 SSMEM1 TSSK1B TPTE2 SMLR1 SPINK7 TPSG1 GRM7AS1 SLC15A5 PIGCP2 TTLL2 SYCE3 SNORD172 TXNDC8 FSCB TKTL2 FABP12 CSN1S2AP SPACA5 TRIM75P OR2L2 ZPLD1 PIWIL1 TCHHL1 FAM87A PRSS45 TRAV2 SAGE1 GLYATL3 ZBBX OR52W1 OR1M1 SERPINI2 SERPINB13 PLA2G4D TRGJP2 RNF222 RFPL4B ADGRF2 GLIPR1L2 SDR16C6P OPN4 RPL13AP17 WSPAR SPATA31D1 G6PC2 SLC9C1 VSIG8 ZNF812P THSD4AS2 OR8B8 RGSL1 TMEM238L SERPINB8P1 ADAM2 PPP4R3C PKDREJ ZNF648 SNORA89 GPX5 OR5BA1P FAM217A TMPRSS2 22 Predicted GPCRs Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). OR6A2 TAAR1 OR13J1 ADGRD2 TAS1R2 GPR142 OR8J1 ADGRF4 OR10V1 OR13C8 OR5F1 OR8S1 OR4E2 FSHR GPRC6A OR5AU1 OR2L2 OR52W1 OR1M1 ADGRF2 OPN4 OR8B8 TMPRSS2 Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR CANT1 FKBP10 FAM71D TMPRSS2 PTEN SPOP SPINK1 TMPRSS3 SLC45A3 DDX5 PRSS58 ESRRA TMPRSS4 KLK3 NDRG1 TMPRSS5 ETV1 ST14 FURIN ETV4 TDRD1 PMEPA1 ERG CRISP3 TMPRSS7 TMPRSS11D FOXA1 ELK4 ETV5 KLK2 TMPRSS13 SPI1 CHD1 HPN HOXC6 KLF5 TM4SF1 ZEB2 PATJ SERPINB5 KLK11 ELF3 SCEL INPP4B TFF1 ESRP1 PSCA TMPRSS11E EHF CEP170 SF3B4 EZH2 PAX8 CCNB2 OTOF BIRC5 MYO7A GATA3 DSCAM ZNF185 KLK4 FOLH1 SPINT2 SPINT1 AR LTF LYPD3 ZNF217 SPDEF RHOU LEF1 KLK5 NR2F2 USP9Y HGFAC TRIOBP TMEM45B DDX4 PLAU ETS1 RBM3 FASN NLGN1 ZSCAN1 LOXHD1 SPON2 LGI2 DLG2 PTTG1 SMARCA5 UXT KPNA3 SNX9 HOXA5 GABPB1 PCDH9 MYO15A BCL11A TFF2 SPIB PRSS1 HNRNPA2B1 CHD4 LAMC2 ETS2 BAZ1A STYK1 ARHGEF3 KLK7 FLI1 S100Z ASTN1 KLK6 GIPC3 TP73 UPK1A ILDR1 OR51E2 CORIN HOXB13 CAMSAP1 MAP3K7 CADM2 ARID1B FLII MZF1 KLK10 ELF5 COP1 PRSS8 TMPRSS6 ZFYVE9 KPNA4 KLK1 KLKB1 MMP7 KLK13 KLK14 MPDZ MAGI2 TMPRSS15 NDUFAF6 ACSM1 KDM3A SETD7 GREB1 ARID1A SEMA6A FOXP1 KLK12 TEX15 GOLM1 DLX1 ELAC2 GLYATL2 KCNH8 SUFU STEAP2 TMC1 SAGE1 KMT2C CRISPLD1 PRSS21 ETV3L MAGI3 OTOA TMPRSS9 LEFTY1 SENP7 MIR222HG MPHOSPH6 TMIE KCNH3 SERPINA5 STRC NKX2-3 TTTY15 ZBTB18 SMARCC2 NPAS3 LIN7C CRISP1 TUSC7 MUC4 ZBTB4 KCNH6 LRTOMT PCDH15 PRSS12 PCA3 NRXN1 TSPEAR CDH10 SCHLAP1 KDM4C JMJD1C PLD5 COL11A2 TMPRSS2 Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR GNA11 MISP FAM3B CAPN5 TMPRSS2 MALL ERGIC1 SLC45A3 MYO1D BAIAP2L1 TMPRSS4 PRR15L KLK3 SDCBP2 NDRG1 ST14 VIPR1 TMEM54 BAIAP2L2 SPTBN2 ST6GALNAC1 EPS8L2 FOXA1 MARK2 KLK2 GOLGB1 IGSF9 PLEKHA7 MYO6 SLC22A23 ARFGEF3 KLF5 KRT4 ERBB3 KLK11 RAB25 ELF3 PPL C6ORF132 MYO5B KIAA1217 C1ORF116 SPRR1A TJP1 KIAA1671 AGR2 EHF NEDD4L AKAP1 NUMA1 SPATA20 ABHD2 CTNND1 SHROOM1 CLDN7 UNC13B B4GALNT3 ESRP2 FAM83H KLK4 FOLH1 CDH1 PKP3 SPINT1 EPN3 CGN ELMO3 TMC4 CYB561 PPP1R16A KIAA1522 CBLC CNKSR1 SCNN1A TMEM184A WWC1 PAK4 JUP CEP170B PTK6 SSH3 SLC9A2 GRHL2 C1ORF106 ARHGEF34P ARHGEF5 CAMSAP3 PROM2 MYH14 CLDN3 BICDL2 EVPL SPDEF MST1R ARHGEF16 B3GNT3 EPS8L1 IQCE CCDC85C TRPV6 KIAA0556 RERE TRPM8 PICK1 ACPP TMEM63B ARHGAP35 BRPF3 RGL2 RBM47 CASZ1 DDR1 TMEM45B TBX3 SPON2 GLB1L2 NPDC1 MUC1 ANO7 RAPGEFL1 CREB3L4 STAP2 LRRC26 CRACR2B LRRC31 CMTM4 PLA2G4F CHRNA2 LMAN1L CWH43 OR51E2 HOXB13 FAAH SIM2 CDC42BPB TGM3 ATP8B1 TSPAN1 ECHDC2 BAIAP2 PPP1R13B ADCY6 PCDH1 FAM3D TMEM30B PRSS8 KLK13 FUT3 PLXNB1 ACSM1 GOLM1 STEAP2 ACACA ZNF664 EYA2 VWA1 PDE9A MLLT4 SLC44A4 DAB2IP AC005077.14 DNAH8 HOMER2 PLEKHH1 PNPLA7 TTC6 SIPA1L3 TRPM4 ARHGEF37 HID1 HIP1R PRAC1 MAST2 CSPG4P10 ARHGAP32 CCDC187 CDK19 DOPEY2 CYP4F30P KRT78 DLG3 ATP2C2 RALGAPA2 TNKS1BP1 SHROOM3 SH3GLB2 PTPRF C9ORF152 EPB41L4B SYT7 SLC37A1 CYTH2 WNK2 GOLGA2P7 CHD6 FXYD3 TSPAN15 HECTD4 TMPRSS2 10 Predicted Kinases Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). MARK2 ERBB3 PAK4 PTK6 MST1R DDR1 CDC42BPB MAST2 CDK19 WNK2 TMPRSS2 9 Predicted Ion Channels Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). TMC4 SCNN1A TRPV6 TRPM8 TMEM63B LRRC26 CHRNA2 TRPM4 FXYD3 TMPRSS2 485 Literature-Associated Genes from Geneshot AutoRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). MAOA NKX3-1 AMACR CANT1 IMPDH2 NBL1 RSRC2 IL6 DPP4 SH3BGR CCL2 CYP11B2 FAM71D TGM4 SEC14L1 STAT3 CYP3A4 SUMO2 EGR1 TMPRSS2 CTSL PTEN SPOP SQSTM1 VDR VCP SPINK1 LOX TMPRSS3 SLC45A3 KPNA2 DDX5 VHL MME MPP5 LSAMP SHQ1 RHOA ESRRA RNF24 TMEM65 ACE2 CACNA1D IFITM3 TLR4 MAST4 TPM4 TMPRSS4 ANXA3 ABL1 RBX1 NDUFAF2 ELAVL1 KLK3 ANXA2 ING5 NDRG1 TMPRSS5 ETV1 ST14 FURIN BRAF RUNX1 ETV4 TDRD1 ESR1 PMEPA1 KLF6 HOOK3 AP2M1 XIAP ERG RYBP SMAD3 CTNNB1 CRISP3 DNMT1 HBD ATM TMPRSS7 TP53 ADAM17 NCKAP5 TRIM25 HLA-A PDE4D ABCG2 B2M TMPRSS11D WASF1 ERBB2 BRCA1 ST6GALNAC1 NT5C FOXA1 NEDD8 BRD4 ELK4 HSPBAP1 SLC16A6 PES1 ETV5 SRC EGFR KLK2 FAM72B UAP1 TMPRSS13 CASP3 GGH PIGU CDK2 MX1 UGT2B17 CHD1 TOP2B UMODL1 GRB2 GPHN OVOL1 GLO1 RIOK2 HPN MYO6 ATF5 NAE1 IKBKB CAV1 HOXC6 CEACAM6 TFF3 KRT18 ITGA2 TGFB2 RARB KLF5 TM4SF1 SIX1 ZEB2 AQP5 SERPINB5 KLK11 PBX1 FOXP2 ITGA10 EPCAM ZEB1 TET2 SEMA3A SLPI ESRP1 PSCA PLA2G7 CCND1 RNASEL CD81 ITGB5 SMAD7 RARA SMARCD1 ABHD2 SRD5A1 TOP2A TK1 EZH2 PAX8 CCNB2 CTSB UBE2C KCNE1 ADAM15 MSR1 ALCAM BUB1B AURKA CDK1 BIRC5 HGF PPARG GAPDH LGALS3 BRCA2 RMI1 CCNB1 CBR1 IDH1 TTK PRDX3 MKI67 HPR LDHA ARNTL2 TYMS ABCB1 ESR2 AKR1C3 PTGS2 NTRK1 NCALD GATA3 MYBL1 ABCC9 CDKN1A MYC NOTCH1 DSCAM ZNF185 KLK4 RUNX2 SLC2A3 ABCC4 MMP1 ABCC6 TGFBR1 PIK3CA BMP4 CDH1 ABCG1 SPINT1 CYP24A1 ITGA2B MTOR MLPH GRHL2 SEMA4B RARG SPDEF WNT11 RHOU LEF1 FGF8 SOX9 SFRP2 ATF3 JAG1 FZD4 MAP2K3 USP9Y WDR5 ADAM7 MEF2A NOTCH2 TFE3 TNK2 CREBBP TBL1X PDLIM5 ERF CDC25C CHEK1 RAD51 CCL20 LCK HOXC5 IL1R2 ASGR1 CD19 DIO2 DAXX PIM1 INHBA TLR3 PLAU SNAI2 CAV2 ETS1 FOS BMP6 HMGN1 GSTP1 BGN HPGD GATA2 PSMB9 SLC34A2 VEGFA BNIP3 VIM ZBTB16 EDF1 FASN SMAD4 IGFBP5 VCL CD9 NTRK3 SPON2 FUS INSR ADRA2A PPP1R15B BAMBI FOXO3 NQO1 PRDX4 WRB HDAC1 PTMA NOC3L APEX1 UBA3 CDK4 MXI1 SOSTDC1 KHDRBS3 FOXO4 TBL1XR1 SNX9 SQLE FAM129A MMP9 CDH6 PCDH9 ETV6 PDK4 RIPK2 SLC16A12 FGFR3 HLA-DMB MCM7 SMC3 HNRNPA2B1 MX2 TTC3 NIPBL IGF1R LAMC2 XRCC4 ESCO1 ETS2 CEACAM1 RCAN1 TRIB2 NMU PANK1 ILK PDXK KHDRBS1 SEPT9 ARHGEF3 CD44 UGT2B15 CYP26A1 CACNA2D3 SRRM4 MMP2 KLK6 GPRC5D CXCL12 PCP4 ACP5 OR51E2 CORIN HOXB13 TBX15 GNA12 CDH2 SKP2 RAD21 OGG1 TSG101 CAMSAP1 PRL UGT2B7 SHBG CDK9 ALK AGO2 RET KDM1A KIT CYP17A1 PRMT1 TBP BSG CXCR4 TERT PARP1 XBP1 TFEB CLPP CA12 EGF MAP3K7 ANXA7 COPA HMBS CADM2 CDC42 HOXC4 EML4 EPHA2 RASSF1 CUL3 SLC39A8 PTPN12 PPP2R2A ZHX2 FLII CHGA KLK10 PLXNA2 NES ERCC1 SMAD2 PBRM1 TAB1 OCLN ZFHX3 GSPT1 SP1 KLK14 LIG4 PRMT5 SENP1 MAGI2 CHD8 CTAG1B EWSR1 E2F3 USP9X PLXNB1 NDUFAF6 ACSM1 GREB1 FOXP1 KDM6A NCOA2 GOLM1 DLX1 PLXNA1 ELAC2 UBTF STEAP2 NANOG RAB27A PIWIL1 PRSS21 JMJD1C DAB2IP IMMP2L PROM1 ENOX1 CAMKK2 SSTR1 SLC2A12 DCLK1 NF1 INHBB CTTNBP2 UNC5C KRAS SRPK1 ASXL1 FERMT1 RING1 PIK3CB TXNRD1 SST CBL BACE2 GCNT1 ABCC10 AMOT CDH11 CDC27 RUNX1T1 RRAS2 DNMT3A BMI1 DLEC1 EHMT2 CYP3A5 NVL ABCA8 SUZ12 OPRK1 NSD1 TSC2 SMC4 SRD5A3 RAB40C HOXD3 PDGFB MEN1 TMPRSS2 48 Literature-Associated Kinases Genes from Geneshot AutoRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). RSRC2 MAST4 ABL1 BRAF ATM ERBB2 SRC EGFR CDK2 RIOK2 IKBKB RNASEL TK1 BUB1B AURKA CDK1 TTK NTRK1 TGFBR1 PIK3CA MTOR MAP2K3 TNK2 CHEK1 LCK PIM1 NTRK3 INSR CDK4 PDK4 RIPK2 FGFR3 IGF1R TRIB2 PANK1 ILK PDXK CDK9 ALK RET KIT MAP3K7 EPHA2 TAB1 CAMKK2 DCLK1 SRPK1 PIK3CB TMPRSS2 7 Literature-Associated GPCRs Genes from Geneshot AutoRIF The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). FZD4 ADRA2A GPRC5D OR51E2 CXCR4 SSTR1 OPRK1 TMPRSS2 Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR CANT1 RSRC2 FKBP10 ANPEP TGM4 TMPRSS2 PTEN SPOP SPINK1 TMPRSS3 SLC45A3 DDX5 SHQ1 ESRRA CACNA1D TMPRSS4 TMBIM1 KLK3 NDRG1 ETV1 ACSL3 ETV4 TDRD1 ESR1 PMEPA1 EHBP1 HSP90AA1 ERG CRISP3 TMPRSS7 TP53 NCKAP5 PDE4D B2M TMPRSS11D ST6GALNAC1 FOXA1 PABPC1 ELK4 PES1 EDEM3 ETV5 KLK2 UAP1 GGH PIGU UGT2B17 CHD1 GPHN HPN GBE1 HOXC6 KRT18 KRT7 TM4SF1 KRT17 ZEB2 ECM1 SERPINB5 KLK11 ELF3 KRT19 INPP4B CLCA2 PSCA PLA2G7 KRT8 RNASEL SRD5A1 DHCR24 EZH2 CCNB2 HSD17B4 EAF2 AURKA PPARG MKI67 ARNTL2 GATA3 AKAP12 EBLN2 ZNF185 KLK4 LTF GRHL2 CDH3 ZNF217 SPDEF SPARCL1 RHOU TCF7 USP9Y SLC45A2 NR2F1 ACPP RXRA PDLIM5 PLA1A UPK3A LPXN TMEM45B CST8 SLC7A11 PLAU ETS1 GSTP1 HPGD PSMB9 FASN EGR2 OLFM4 SPON2 GALNT7 HOXB7 KPNA3 TCF15 CREB3L4 CSRP1 SLC16A12 TFRC HLA-DMB AGR3 HNRNPA2B1 TTC3 ETS2 TRIB2 PANK1 ACTN1 SESN1 UGT2B15 HSPA1L KLK7 TWIST1 ETV3 ATP8A2 OR51E2 CORIN HOXB13 CAMSAP1 CTCF KDM1A SOX5 CA12 MAP3K7 ANXA7 ANXA4 THOC7 ZHX2 KLK10 SPRED1 KLK1 MMP7 KLK14 LRP1B MAGI2 ACSM1 KDM3A SETD7 GREB1 ARID1A AZGP1 KDM4A FOXP1 KDM6A NCOA2 DLX1 ELAC2 GLYATL2 KCNH8 UBTF STEAP2 CDK19 IMMP2L ENOX1 DCLK1 GCNT1 ABCC10 ABCA8 OPRK1 RAB40C SLC25A26 NT5C1A DTYMK RDH11 SLC16A14 ATOH7 FXR1 FOXP4 BHLHA15 MTAP SETD5 PTP4A3 PGM3 CSMD1 CCNG2 NME6 GPM6B P4HA2 TMPRSS2 8 Predicted Kinases Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). RNASEL AURKA TRIB2 PANK1 MAP3K7 CDK19 DCLK1 DTYMK TMPRSS2 Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR F2RL1 SUMO1 CANT1 NBL1 PRKCZ HSPA5 MVP TGM4 TMPRSS2 PTEN SPINK1 TMPRSS3 SLC45A3 DDX5 MPP5 ESRRA KLK3 ANXA2 CDX2 NDRG1 HOOK1 ETV1 ST14 ADAM9 RUNX1 ETV4 ESR1 EHBP1 ERG TMPRSS7 ADAM17 TMPRSS11A TMEM176A CSNK2A2 ERBB2 ELK4 ETV5 KLK2 ELOC USP7 CHD1 CAV1 TFF3 MCF2L KRT7 MSMB KLK11 TP63 NDRG2 TMPRSS11E CCND1 BANF1 RNASEL AKT1 CIC TOP2A CTSB EAF2 FAM72D FAM72A MSR1 HGF FAM72C MKI67 KCNMA1 CXCL8 ESR2 AKR1C3 GATA3 IGFBP3 B4GALT1 KLK4 MMP1 PIK3CA SPINT2 WNT1 SPINT1 AR NCOA3 LEF1 FGF8 SOX9 KLK5 SLC45A4 CREBBP AOAH DNPH1 NT5C3A BTBD16 DAXX PLAU SNAI2 ETS1 KLF4 FOS EGFL7 JUN CLDN5 BCL6B NUPR1 CALR ANXA1 RASSF5 RGS5 PDX1 SLC5A5 CCND2 GNPDA2 WDR12 MYH7B CTBP2 DOK4 TDRD7 CEP131 NALCN DYNC1LI1 BOP1 XRCC4 ETS2 UGT2B15 ATF7IP KLK7 FLI1 MMP2 ROR1 PIWIL2 KLK6 TAL1 OR51E2 GABRR1 HOXB13 OGG1 ADGRE1 CTCF RET KDM1A NKX2-1 MMP14 NEDD4 ASTN2 SPINK4 SHH KCTD15 KLK10 ELK3 COP1 HNF1B KLK1 MMP7 NA SP1 KLK13 KLK14 MUC2 GDNF SRF JAZF1 LMTK2 CTAG1B CDKN2A EWSR1 PLXNB1 KDM4A FOXP1 KLK8 KLK15 CCAR2 TDRD6 ELK1 UBTFL1 KRT34 WWTR1 SLC22A3 ADGRE3 1810009J06RIK TMIE SLITRK2 MIR19B-2 DPY19L3 KRT72 YAF2 CRISP2 MIR17 MRTFB GALNT6 TRA2A CBX7 IIGP1 GABRR2 A1BG FANK1 CNTNAP2 PIK3C2A DDX27 MGAT2 PCM1 C15ORF53 IFT57 TMPRSS2 10 Predicted Kinases Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). PRKCZ CSNK2A2 ERBB2 RNASEL AKT1 PIK3CA ROR1 RET LMTK2 PIK3C2A TMPRSS2 Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). GPR151 RNF133 FAM71D TGM4 SLC2A7 TRIM42 TAAR1 SAXO1 SLC4A9 SMIM2IT1 TERB1 ZP2 SNX31 TMC2 GPR142 TEX36 SMCO2 PICSAR ODF1 TMEM236 TPRG1 FAM83B SMIM31 TMPRSS11E VSIG10L FMO9P SYT14P1 RNU667P ZC3H18AS1 HS6ST2AS1 THRBAS1 TCP10 OR7E91P OPN5 GPC6AS2 OR5G1P SPINK14 TMEM207 HSF2BP SMIM23 SVOPL FBXO16 TCP11 TMEM260 TMCO5A AKR1E2 ZNF484 SAMD15 TBC1D19 ZNF322 TTC21B SPESP1 SAMD13 STRA8 ZSWIM2 ANKRD31 APOBEC4 ZMYND12 THAP9 ZC2HC1B STX19 TAC4 TTC8 PRSS38 SDR9C7 FTCDNL1 PMFBP1 GOLGA6C SLC9A9AS1 WDSUB1 ZDHHC13 SLC35F5 COX7BP1 TBX19 SLC10A7 RAET1L ST20MTHFS WASF4P OFCC1 STMND1 UBE2U SPERT SNORD168 GPC5AS1 VWA2 WEE2 TRIM60 TMC1 TBPL2 SPINK13 SSMEM1 SMLR1 TTLL2 SNORD172 TXNDC8 FSCB FABP12 ZPLD1 TCHHL1 GLYATL3 RFPL4B ADGRF2 RPL13AP17 SLC9C1 THSD4AS2 TTC6 CSNK1A1P1 SIGLECL1 YY1P2 OACYLP TMEM241 TRDMT1 PLEKHA8 FRMD6AS2 RGMBAS1 FAM187A SEC14L1P1 TRIQK SMC2AS1 TMEM168 SATL1 TMEM254 SPATA32 GALNTL5 STPG2AS1 ANKAR FOXP4AS1 HNRNPLP2 FBXL19AS1 XKR9 STEAP3AS1 TIGD4 ZNF774 RNF32 FTOIT1 HNRNPKP3 CPSF4L SCARNA27 FBXO43 ZCWPW2 FANK1AS1 SUMO1P1 SNORA70F TEX43 AHCTF1P1 HSD3BP1 GPC6AS1 STX18IT1 OC90 POU6F2AS1 SAMSN1AS1 GEMIN8P4 TOMM20P4 SMIM2AS1 FSIP1 TMEM78 GLIS3AS1 SNAP23P1 ZNF620 AQP4AS1 RBMS3AS3 PLS3AS1 ZNF705E FER1L6AS1 R3HCC1L TPI1P3 SAMD7 TXNRD3NB SUN3 TLK2P1 STPG1 TTC41P AK9 TMEM211 TTC26 ZNF487 ZNF396 THUMPD2 AOX3PAOX2P SAMD12AS1 FER1L5 GPHB5 TPTE2P2 TTC29 SYNJ2IT1 RBMS2P1 TBC1D12 FER1L6AS2 SNORA105B ZHX1C8ORF76 FAM227B GRXCR2 ZAR1L PLEKHG7 SERPINE3 WISP3 TTC30A ERICH6 FAM9C TM4SF1AS1 TMPRSS2 5 Predicted GPCRs Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). GPR151 TAAR1 GPR142 OPN5 ADGRF2 TMPRSS2 Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR CANT1 RSRC2 FKBP10 SH3BGR TMPRSS2 PTEN SPOP SPINK1 TMPRSS3 SLC45A3 DDX5 SHQ1 TMPRSS4 TMBIM1 KLK3 NDRG1 TMPRSS5 ETV1 ST14 ETV4 TDRD1 PMEPA1 EHBP1 ERG CRISP3 TMPRSS7 NCKAP5 TMPRSS11D FOXA1 ELK4 EDEM3 ETV5 KLK2 PIGU UGT2B17 CHD1 CLDN10 HPN MYO6 HOXC6 KLF5 TM4SF1 SIX1 ZEB2 SERPINB5 KLK11 ELF3 SCEL KRT15 INPP4B TFF1 PSCA TMPRSS11E EHF MEIS1 SF3B4 EZH2 PAX8 CCNB2 OTOF BIRC5 MYO7A TTK ARNTL2 GATA3 AKAP12 TGFBR3 EBLN2 DSCAM ZNF185 KLK4 FOLH1 SPINT1 AR ZNF217 SPDEF RHOU FGF17 OTX1 USP9Y SLC45A2 CACNA1H HGFAC ADAM7 TRIOBP TBL1X PLA1A TMEM45B CCNE2 PLAU NEGR1 ETS1 SH3BGRL LITAF H2AFY FASN EGR2 OLFM4 LOXHD1 SPON2 QPCTL LGI2 GALNT7 UXT CREB3L4 HOXA5 MYO15A PCGF5 SLC16A12 SPIB AGR3 CLDN14 HNRNPA2B1 TTC3 ETS2 ETV7 PANK1 SEPT9 S100Z GIPC3 UPK1A ATP8A2 ILDR1 PCP4 OR51E2 CORIN HOXB13 MYCN C3ORF14 CAMSAP1 CTCF SOX5 MAP3K7 ASTN2 SLC39A8 THOC7 ZHX2 KCTD15 KLK10 TRPC4AP ELF5 COP1 PRSS8 ZFYVE9 KLK1 KLKB1 KLK13 CDH15 KLK14 LRP1B MAGI2 TMPRSS15 NDUFAF6 GREB1 FOXP1 GOLM1 DLX1 ELAC2 GLYATL2 KCNH8 STEAP2 GABPA TMC1 KMT2C PRSS21 OTOA TMIE KCNH3 TTTY15 ZBTB18 PCDH15 PCA3 TSPEAR SCHLAP1 COL11A2 IMMP2L ENOX1 ABCA8 RAB40C SLC16A14 ATOH7 FXR1 PTP4A3 CSMD1 NME6 GPM6B P4HA2 ZBTB21 CTCFL OR51E1 SATB2 USH2A ZNF578 RNF14 RAB33A RNF121 FENDRR MSRB3 TMPRSS2 Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). NKX3-1 AMACR FAM3B TMPRSS2 TRIM42 ERGIC1 PTPN3 SLC45A3 BAIAP2L1 KLK3 TDRD1 ERG FAM71C FAM71B GIGYF2 FOXA1 ELK4 KLK2 GOLGB1 ENTPD5 MYO6 SLC22A23 ARFGEF3 ERBB3 TTC39A PATJ KLK11 RAB25 ELF3 C6ORF132 KIAA1217 HUNK GALNT3 C1ORF116 UTRN ESRP1 EHF MYO5C MAP7 NEDD4L AKAP1 NUMA1 SPATA20 ABHD2 SHROOM1 ALOX15B NRIP1 ESRP2 SLC30A4 KLK4 FOLH1 ABCC4 FAM83H-AS1 AR EPN3 MLPH TMC4 KIAA1522 TMEM184A WWC1 PTK6 SLC9A2 GRHL2 FAM83F PROM2 BICDL2 EVPL SPDEF TRPV6 PHF12 GTF2IP20 ST6GALNAC2 RERE TRPM8 ACPP RBM47 CASZ1 PDLIM5 TMEM45B MICALCL SORD GATA2 NUPR1 LCA5L TBX3 AXDND1 SPON2 MARCH10 GLB1L2 ANO7 DUSP21 CREB3L4 LRRC26 USP25 CLDN8 CRACR2B NCAPD3 LTN1 ETS2 SON DYRK1A BACH1 PLA2G4F FAM71F1 CHRNA2 LMAN1L TNP2 CWH43 CPNE4 OR51E2 HOXB13 FAAH SIM2 PPP1R13B URB1 RIPK4 OR2H1 UBE2U ACSM1 GOLM1 STEAP2 ACACA KMT2C PDE9A SLC44A4 AC005077.14 DNAH8 HOMER2 PNPLA7 TTC6 SIPA1L3 TRPM4 ARHGEF37 HID1 PRAC1 ARHGAP32 CDK19 DOPEY2 CYP4F30P ATP2C2 RALGAPA2 SHROOM3 C9ORF152 SYT7 SLC37A1 CHD6 HECTD4 BACE2 SPATA32 ZBTB21 RP11-798K23.3 SPATA31A3 GOLGA6D CHD2 LELP1 SPATA31C2 OR5E1P ZNRD1ASP RP11-1023L17.2 GTF2IP13 METTL21AP1 HLA-V SPATA31A1 C21ORF140 TMCO5B LRRC52 GOLGA6L10 RP11-244K5.6 GTF2IP12 POTEI OR7E47P RPL7P16 DRICH1 TPPP2 POTEH MBOAT2 CLMN AP000295.9 RP11-124L9.2 NSUN4 TCP10L HLCS IGSF5 SPATA31D5P ARHGEF38 HSFY1P1 POTEM NPIPB4 SPANXN1 SSR4P1 MIA3 OR7E104P ZCCHC6 MROH7 DNAJB7 C20ORF173 TRGV9 SPANXN2 ARHGAP6 HMGN2P46 TMPRSS2 6 Predicted Kinases Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). ERBB3 HUNK PTK6 DYRK1A RIPK4 CDK19 TMPRSS2 7 Predicted Ion Channels Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity The spike protein of SARS-CoV-2 is primed by TMPRSS2; SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming (Hoffmann et al. (2020) Cell, 181(2): pp.271-280). TMC4 TRPV6 TRPM8 LRRC26 CHRNA2 TRPM4 LRRC52 100 gene most correlated to LDLRAD4 based on ARCHS4 co-expression LDLRAD4 was suggested to be associated with COVID-19 based on a recent GWAS of the UK Biobank PMEPA1 SIRPA TREM2 LNPEP CABLES1 RPS6KA5 ARFGEF3 NT5E C1QC C1QA ITGB5 RHOB HEXB NRIP1 NUAK1 TGFBR2 TGFBR1 FEZF2 ARHGAP27 IL10RA SELPLG LCK CX3CR1 CD3E PREX1 CTSS LGMN GPR34 PCOLCE2 DGKZ SPARC PLXDC2 CSF1R EIF4A2 FAM102B P2RY12 IER5 MSL2 HIVEP2 FAM189A1 P2RY13 CHAD RHOH KCTD12 PAG1 OLFML3 HSPA1B DPP8 NFATC1 NFATC2 LPCAT4 ATXN1 COL27A1 SMAP2 PDE3B PELI3 WDR1 DGKI PDGFB IL6ST PITPNM2 CYB5R2 MFI2 SIGLECH ZFAS1 SRGAP2 GM38393 GM7027 GM45062 TRBV19 PPAN ABCA9 1810032O08RIK SYNJ2 RTL1 VSIR GM21985 TMEM119 KCNAB1 ZFP101 AP3M1-PS GM7340 ZFP609 EIF5A2 GM19202 GM29797 WISP1 MAP3K5 1700008O03RIK ARSB SLC12A6 GM9913 DYRK2 TNPO2 TMEM144 TPBGL GM17828 RNF225 GM12928 COL10A1 Chloroquine 13 Literature-Associated Ion Channels Genes from Geneshot GeneRIF Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). P2RX4 SCNN1A TRPM8 KCNN4 CACNA1G TRPV1 KCNH2 TRPA1 KCNJ2 GRIN2B TRPV4 MCOLN1 CACNA1C Chloroquine Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). MAPK3 HSPA5 CTSL SQSTM1 UBD MAP1LC3A TRIB3 ESRRA ATF6 SLC22A18 NBR1 GABARAPL2 BAG3 HSP90AA1 NFKB1 MAPK14 FYCO1 CTSD BIRC2 CANX NLRX1 RAB7A PCK1 TAS2R38 IFNB1 RPS6KB1 VAMP8 ATP6V1B2 BCL2 DEPTOR PAWR HSPB8 PRKAA2 GADD45A RPS15 UNC93B1 ATG16L2 ATG4B TRPV2 CTSB MYO1E GRB10 SPTLC2 CDKN1C KLF10 TGFBR2 SERPINF1 TGFBR1 ACTB CYCS MTOR JUP LAMP1 GABARAPL1 TAS2R7 ULK1 ATG2A GATM CTSS HSPB3 IGFBP6 IRGM ATP2B2 IGFBP4 MAP1LC3B CRYAB TGM2 RHEB DRAM1 RPL26 LAMP2 GABARAP COX4I1 BNIP3 TP53INP1 TOMM20 ATF4 VTI1B CSNK1A1 RAB9A RAB5A BNIP3L ACSM2B DLK1 DDIT3 TAS2R46 SLC38A4 INSR TP53INP2 FOXO3 CIDEB VMP1 ATG5 EIF2A VAMP7 RB1CC1 MUL1 PSD3 CDKL3 PKD2L1 MAP3K8 ATP6V0D2 INPP1 CASC3 GBP1 TICAM1 SOD2 PXK ZKSCAN3 IGF2 TRPM3 RARRES1 PRKCD RUBCN EEA1 WIPI2 XBP1 TFEB CALCR STX8 SH3GLB1 ATG9A BAK1 PRKCA CALCOCO2 PIK3C3 ATG12 WIPI1 UVRAG ATG3 CLTC BLOC1S1 BECN1 ULK3 ZFYVE26 ACSL1 ATP6V0A1 DAPK3 MFN2 ITGA3 PELI3 SNAP29 IGF2R FAM3C ACSM1 NCOR1 INHBB TIGAR BCL2L11 ATG7 ATG10 PRKAA1 DAPK1 EIF2AK3 PHF23 TAS2R4 STX17 BNIP1 FIG4 CCDC85A AP3B2 ATG101 ATG4C EIF4EBP1 ATG13 NXPH3 BANK1 RPTOR AMBRA1 WDFY3 PRR5 RAB9B CUL4A SPG11 TMEM192 SCHIP1 CPT1B DRAM2 MEOX1 TAS2R3 ATG16L1 TMEM74 EVA1A ATG4A ULK2 ATG2B TP53BP1 PEG3 ZFYVE1 MAP1LC3C FUNDC1 ATG4D ATG14 TAS2R14 PCDH17 FAM133B CISD2 TAS2R10 PIK3R4 EPG5 Chloroquine Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). TRIM55 BCL2L1 MAPK3 HSPA5 CCL5 SQSTM1 MAP1LC3A IRF3 ESRRA TLR4 AP3B1 NBR1 YWHAE GABARAPL2 ESR1 BAG3 NFKB1 MAPK14 FYCO1 CALM1 UBQLN1 TP53 TMEM173 GNB1 TAS2R38 HSPA8 UBQLN2 CASP3 MYD88 MAPK1 RPS6KB1 VAMP8 BCL2 CXCL1 HIST1H2AG RICTOR PRSS16 BAX UNC93B1 ATG16L2 ATG4B AKT1 FKBP8 HDAC6 UNC13D CTSB E2F1 BCAT1 CXCR2 ZNF184 STK4 BAD PIK3CA MAPK8 MTOR COL17A1 WNT3 SFRP1 DVL2 LAMP1 WNT5A IRF8 GABARAPL1 ULK1 CXCR3 ZBP1 TLR1 SLAMF1 TLR7 CD86 CYBB SNCA PML MAP1LC3B HMGCS1 DRAM1 LAMP2 GABARAP BNIP3 TP53INP1 RAN ADAMTSL2 BNIP3L TLR6 TLR9 INSR FOXO3 HMGB1 ORMDL2 VMP1 HDAC1 ATG5 RB1CC1 DDB2 NCOA4 RIPK3 CSK TLR2 TRIM21 MAP3K8 PIK3CG PIKFYVE FGFR3 RASD2 EIF3A PIK3R1 PMAIP1 TICAM1 IRS1 BTN3A2 SERPINA1 CASP8 KLRK1 CAST SLC17A3 SPOCD1 TLR8 CCL3 RUBCN TRAF6 TSG101 NPC1 BCR TFEB NEDD4 ATP2A2 TRIM54 STX8 SH3GLB1 BAK1 CALCOCO2 PIK3C3 ATG12 UVRAG ATG3 BECN1 RASSF1 SMPD1 ATP6V0A1 RAF1 HLA-DOB RAET1G RAET1L SELENOK NFE2L2 CRYBA1 IGF2R NA MRGPRD CHDH KEAP1 CDKN2A EWSR1 USP9X KDM4A UBTF TRIM50 KRAS TSC2 TRDMT1 H2-OB RAB7 LRSAM1 BCL2L11 ATG7 PRKAA1 H2-OA DAPK1 RACK1 EIF2AK3 PHF23 ATG4C ATG13 BANK1 RPTOR AMBRA1 TAS2R3 ATG16L1 ULK2 MAP1LC3C ATG14 PIK3R4 MREG TLR5 TAS2R31 POM121L2 LRRC59 POLR2F TRP53INP2 DCAF1 HIST1H2BJ TLR10 VPS52 SERPINA1A AP3S2 KAT2A CCL6 TAS2R42 BLK FSD2 Chloroquine Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). ERICH4 TMEM202 OR1L3 OR8D2 H1FOO TRIM42 TAAR1 TAAR8 TEX35 SPACA3 OR1F2P SIRPD OR13J1 OR1F1 TAS1R2 TAAR9 HIGD1AP11 TMC2 GPR142 ETDB OR10H1 TAS2R38 ODF1 SPEM1 PPY2P TMEM150B SLC2A9 RPS15AP36 HNRNPA1P27 ZNF707 RSL24D1P1 FMO9P OR2S2 VN1R5 ACTR3P2 OR7E91P OPN5 OR6C4 OR2A5 OR2B3 OR12D3 OR1E1 TAS2R8 GPR31 TMEM52B SMIM23 PGPEP1L FAM223B SLC22A14 OR4S1 OR2B6 APOBEC4 SEPT7P9 SPDYE1 TAS2R41 GOLGA6A PRNT ZC2HC1B SPATA25 OR51A1P TAC4 TAS2R60 TAS2R50 SERPINB9P1 OR2H2 SLC9A9AS1 COX7BP1 HMGB1P3 HMHB1 TRIM6TRIM34 SSMEM1 TTLL2 TXNDC8 FABP12 OR52W1 OR8B8 FAM187A SPATA32 ZCWPW2 SUMO1P1 HSD3BP1 SNAP23P1 TXNRD3NB ZNF487 GPHB5 SYNJ2IT1 FER1L6AS2 ZAR1L PLEKHG7 TCP10L SSR4P1 NUTM2D OR4C45 PRCD SRD5A3AS1 SNORA110 SDC4P PRELID1P4 OR2S1P OR6N1 TMEM110MUSTN1 PRR25 RNASE8 TEX44 GOLGA6L3 TMED7TICAM2 PRR34 FAM136BP WASHC2D ARF4P4 HAR1B TOP1P2 TXNDC2 COX6B1P3 ETF1P2 GNRH2 TPM3P8 FAM35BP RHEBP2 TMEM72AS1 RPS10P27 GOLGA8Q ST7AS2 TEX29 GLT6D1 PEAK3 PRAMEF19 APOL5 ZBTB20AS1 ACE3P RIMBP3B HIGD1C EWSAT1 FCF1P8 ZACN ADORA2AAS1 TMEM174 TPRKBP2 ARGFXP2 SDCCAG3P2 FAM192BP TEX21P RPL36P18 TMEM51AS1 ZFATAS1 GAPDHP73 TTTY7B SPATC1 RN7SL328P GRAPL CPEB2AS1 OR1L8 OR2Y1 FAM71A RN7SL385P SNORD103A FTH1P14 TRAV21 ACOXLAS1 FAM226B PDLIM1P1 OR1K1 SDIM1 RPL6P29 ZNF259P1 PPIAL4D RPL23AP1 ZNF861P ZNF205AS1 PTP4A2P1 RUNX1IT1 VN1R105P OR4D9 SNORA70B RRN3P2 STKLD1 GSTM2P1 RPS3AP38 OR10P1 OR2V2 SPDYE6 TMEM262 CRYMAS1 SDHDP6 FTH1P22 SPATA12 CPS1IT1 HCP5B OR52D1 GOLGA6B PIGHP1 TEX22 ANKRD26P4 SNHG28 SPATA9 TEX36AS1 GRK5IT1 RPL34AS1 GCNT7 PIK3CDAS1 Chloroquine 39 Predicted GPCRs Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). OR1L3 OR8D2 TAAR1 TAAR8 OR1F2P OR13J1 OR1F1 TAS1R2 TAAR9 GPR142 OR10H1 TAS2R38 OR2S2 VN1R5 OPN5 OR6C4 OR2A5 OR2B3 OR12D3 OR1E1 TAS2R8 GPR31 OR4S1 OR2B6 TAS2R41 TAS2R60 TAS2R50 OR2H2 OR52W1 OR8B8 OR4C45 OR6N1 OR1L8 OR2Y1 OR1K1 OR4D9 OR10P1 OR2V2 OR52D1 Chloroquine Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). BCL2L1 EIF3F HSPA5 SQSTM1 MAP1LC3A ATP6V1A ATF6 SLC22A18 NBR1 GABARAPL2 BAG3 USP2 FYCO1 CTSD FBN1 NLRX1 RAB7A VPS39 TAS2R38 RPS6KB1 VAMP8 EI24 NAGLU BCL2 DEPTOR HSPB8 PRKAA2 RPS15 BAX UNC93B1 BANF1 ATG16L2 ATG4B CTSB GRB10 FGFRL1 KLF10 SLC2A8 CD300C LAMP1 GABARAPL1 SOX6 OSBPL1A TAS2R7 TAS2R16 ULK1 ATG2A AKT1S1 AAK1 IRGM ATP6V0C MAP1LC3B RHEB DRAM1 RPL26 LAMP2 GABARAP NUPR1 BNIP3 TOMM20 STUB1 ATF4 RBBP4 VTI1B RAB5A BNIP3L TAS2R46 FAM167A SLC38A4 INSR TP53INP2 FOXO3 CIDEB ATP6V1E1 BFAR ATG5 EIF2A VAMP7 RB1CC1 HNRNPA0 PPP3CB MUL1 PSD3 CDKL3 ATP6V0D2 INPP1 GABRE CASC3 HNRNPA2B1 GBP1 TICAM1 PXK CNPY3 ZKSCAN3 SESN2 PHLDA2 STK17A RUBCN PSMG2 YKT6 SOX5 EEA1 WIPI2 XBP1 TFEB TRIM63 SH3GLB1 ATG9A BAK1 CALCOCO2 PIK3C3 FADD ATG12 WIPI1 STX12 UVRAG ATG3 BECN1 CAMKK1 PINK1 ULK3 VPS18 ZFYVE26 TPP1 DAPK3 PELI3 SNAP29 UBE2Q1 IGF2R FAM3C INHBB EHMT2 TIGAR MCOLN1 ATG7 ATG10 PRKAA1 DAPK1 TAS2R4 STX17 BNIP1 CCDC85A AP3B2 ATG101 ATG4C EIF4EBP1 ATG13 NXPH3 BANK1 RPTOR AMBRA1 WDFY3 PRR5 RAB9B CUL4A TMEM192 SCHIP1 DRAM2 MEOX1 TAS2R3 ATG16L1 TMEM74 ATG4A ULK2 ATG2B PEG3 ZFYVE1 MAP1LC3C FUNDC1 ATG4D ATG14 TAS2R14 FAM133B CISD2 TAS2R10 PIK3R4 EPG5 BLK TIMM23B ASB15 DDIT4L RNFT1 ZFAND5 RAB33B FBXO32 IQCJ-SCHIP1 HAGLROS PRR5L VAC14 SLC38A9 ADAMTSL4 CRTC2 RMC1 MAPKAP1 VPS16 WDFY1 MAP1A COQ10B CARD10 RTL10 Chloroquine Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). SLC36A1 FCGRT CD14 LILRB2 SLC7A7 CXCL16 ARRB2 LYN KCNQ1 SIRPA ACAA1 SIRPB2 FERMT3 IL17RA LILRB1 SPI1 BRI3 MTMR14 ATP6V1B2 RILP STXBP2 MGAT1 PLEKHO1 NINJ1 IGSF6 PLA2G7 AIF1 FTL UNC93B1 MAN2B1 ITGB2 C1QC ITGAX C1QA ALOX5 LRRC25 EMILIN2 TYMP CYBA PLEKHO2 SLC15A3 ITGAM SLAMF8 ARAP1 GRN TOLLIP HK3 SLC11A1 C3AR1 C1ORF162 CAPG CTSB RAB20 ADAP2 LILRB5 RENBP FGD2 MS4A4A TMEM150B IRF5 CTSZ MAFB CD163 CD300C BCL3 GLT1D1 ZMYND15 CEBPB AP5B1 SLC37A2 IRF7 AOAH MS4A7 LILRB4 PIK3R5 FCGR1A CLEC4A SECTM1 CLEC7A VAV1 FCGR2B MYO1F CTSS FCER1G CD84 CD86 SIGLEC1 OSCAR CLEC4E PTAFR LGMN TCIRG1 NFKBIE GLIPR2 C5AR1 FTH1 RHOG LITAF OAZ1 TYROBP IFI30 CSF1R PSAP LAPTM5 RNASE6 HCK THEMIS2 NCF4 EFHD2 LST1 SIGLEC7 SIGLEC9 CAMK1 CYTH4 ARHGAP25 TNFRSF14 ATP6V0D1 B3GALT4 MMP9 TLR2 SLC43A2 LY96 SIGLEC10 RNF19B LGALS9 MX2 NAPA RHBDF2 MOB3C RNF149 CTSA RNASET2 DENND3 FCGR1B ADAM8 NCF1 CD68 STAB1 ACP5 CECR1 IL10RB PRKCD PILRA NCF1C APOBR NAGK TBXAS1 SIGLEC5 LILRB3 HPS1 LILRA6 LILRA5 FGR NCF2 C19ORF38 FCGR3A SIGLEC14 RGS19 AQP9 DOK3 HLX TFEB IFNGR2 RAB4B STX4 TOM1 ELL LACTB AP5Z1 ASAH1 EEPD1 GNPTG AMDHD2 ACSL1 YPEL3 TPP1 ACP2 FAM214B MFSD7 SLC31A2 NPL AMPD3 NLRC4 IL6R NFAM1 MCOLN1 CMKLR1 RNF130 ADGRE2 MKNK1 ARSA FPR3 SLC8B1 IGFLR1 LILRA2 SLC26A11 SCARF1 CYB561A3 TNFSF13 CYP27A1 Chloroquine 890 Literature-Associated Genes from Geneshot AutoRIF Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). GLA CD79B CASP6 SUMO1 SLC10A2 IL2 CD209 IFNAR1 IL1B BCL2L1 IL6 MAPK3 DPP4 HSPA5 IDE CCL2 NOX4 CD34 ABCC1 STAT3 CYP3A4 TRIM59 CTSL PTEN IL17A SQSTM1 VDR VCP LOX MAP1LC3A TNF IRF3 HRAS TRIB3 SLC1A1 DDX58 VHL TBK1 NPC2 RHOA CXCL10 RIPK1 TLR4 EP300 CTLA4 PPT1 TIMM9 ATF6 ABL1 NBR1 ATXN3 ANXA2 LYN GABARAPL2 REG3A SLC5A1 NDRG1 FURIN EPS15 BRAF RUNX1 HSPB1 JAK2 BAG3 AP2M1 XIAP EHBP1 IFNG WRN SMAD3 CTNNB1 RAB8A HMOX1 IL4 GPX1 TREM2 AQP2 OAS1 UBQLN1 DNMT1 ATM HLA-DRB1 CTSD TP53 ADAM17 RELA ACE STAT1 TRAF3 HLA-A VARS ABCG2 B2M ERBB2 BRCA1 TRIM28 CD7 RAB7A APOBEC3G OASL PHB PTH NOS3 CLEC4M CXCL2 IFNB1 TGFB1 ISG15 SRC EGFR HSPA8 ARF6 APP NTS SPI1 CXCL9 RAB10 SCARB1 CASP3 IL10 CDK2 MX1 MYD88 MAPK1 SLC39A5 GRB2 RPS6KB1 SPTLC1 VAMP8 TPMT TFAM KDR ATP6V1B2 CD55 CPT1A TRIM37 IKBKB MCL1 CAV1 ALB CHEK2 DCTN2 BCL2 MT-ND3 CXCL1 TGFB2 TNFSF10 ASS1 CFTR ERBB3 MT-ND1 AQP5 NR4A2 YAP1 PTPN13 LMO7 OSMR PAWR SOX2 RICTOR HSPB8 PRKAA2 SLC2A1 GADD45A TJP1 MT-ATP6 CCL8 ISG20 LCN2 ANK3 ABCA1 AIF1 MT-CO2 CCND1 NEDD4L BAX PNPLA2 UNC93B1 SLCO2B1 AQP3 THBS1 SHC1 SLC3A2 ATG4B AKAP1 AKT1 APOL1 ALOX5 HDAC6 GRK2 CD81 LRP1 UNC13D ORAI2 MARCO SMAD7 ITGAM RARA NRP2 GRN SLC38A10 NLRP1 PLK1 TIMP1 TOP2A P2RX4 EZH2 LMNB1 MACC1 CTSB FZD2 LPL HADHA GLRX MYO1E LDLR CDK5 FLT3 DDIT4 ANXA5 VDAC1 CDC25A AURKA GPNMB RRM2 CDK1 CTSZ CDC6 CD163 HGF PPARG IL18 GAPDH GRB10 LGALS3 CCR2 BRCA2 CCNB1 IDH1 HP LDHA LIPA SPTLC2 MAP3K6 TYMS KIR2DL1 ABCB1 CXCL8 AKT3 CXCR2 PTGS2 GATA3 KLF2 SLC2A4 CDKN1A MYC HINT1 NOTCH1 RUNX2 MAVS ABCC4 PKD2 COL1A1 AVP MMP1 STAR ABCC2 APLP2 AXL PIK3CA STAT5A BATF BMP4 ABCG1 SLC2A2 FGFR1 ACTB BDNF CYCS TF MITF INS MAPK8 FOXM1 LTF MTOR CLDN3 WNT3 COL1A2 CLU RAB4A AXIN2 MAF BGLAP WNT16 DVL2 LRP5 WNT3A LAMP1 WNT5A DACT1 WNT2 SP7 GABARAPL1 HNRNPK TYRP1 GOLPH3 CD63 MLLT11 HIF1A ATAT1 TAS2R7 FZD9 TFE3 TRPV6 CEBPB TRPM8 MNT ULK1 SAA1 MEFV CYSLTR2 CXCR3 CDC25C CD69 IRF7 CHEK1 RAD51 CCL1 TLR1 CD5 CD27 LCK CX3CR1 GP2 TOX H2AFX STAT4 CCR5 KCNN4 FABP4 ADIPOQ CCK RYR2 CYP1A1 CYP2E1 CCL17 ALOX15 TLR7 CD86 C3 SIGLEC1 CD274 KCNJ10 CCR1 BCL2L15 CTSK CYBB OSCAR SNCA CD19 COL3A1 DHFR TIMELESS IFIH1 HMGCS2 CLDN2 SOCS3 ARSI TREM1 DIO2 ADAR PTGES NOD2 SLC39A14 SOCS1 TLR3 CD59 UCP3 BMPR2 KLF4 CDH5 YBX1 FOS MAP1LC3B IRF1 ADIPOR1 TXN ICAM1 NFKBIA HPGD PCBP1 RHEB CLDN5 CA2 DRAM1 VEGFA SFTPC UCP1 SNX17 LAMP2 CTSH ALDH1A1 NR1D2 GABARAP IFI44L PSMB5 NUPR1 SLC12A2 COX4I1 BNIP3 DDX3X VIM TOMM20 STUB1 TYROBP SOD1 ATF4 AQP1 RAB11A CYP2B6 TCF4 VWF HCK HLA-DMA PHLDA1 VPS35 NRP1 SMAD4 RAB3GAP1 RAB5A SLC38A2 CD9 BNIP3L DLK1 CYP1A2 DDIT3 SLC12A1 MT3 TRPC3 TRAF1 NR4A3 GFAP NOS2 MRGPRX1 SCARA5 SYP FNDC5 IL13RA2 ABCA4 CYP7A1 ESRRG LRRK2 MRC2 TNFAIP3 TLR9 VIP TG AICDA NPPB INSR NEUROG3 TP53INP2 AQP4 BBC3 NGF PFKFB3 FOXO3 FOSB NQO1 M6PR MIF HMGB1 ASL COPS5 VMP1 HAVCR1 TIMP2 LMAN1 VRK1 DKC1 ATG5 GJA1 EIF2A LDHB CDK4 RB1CC1 SIRT1 SLCO2A1 GRB7 MLH1 GLB1 HAMP ID1 MAP1B RIPK3 HDGF CREBRF MAP2 MMP9 BCHE HTR1B CD47 PCSK1N REL CIITA HLA-G VRK2 KCNJ11 MYH2 TLR2 CASP1 MMP13 CSF3R CD40 BID USP25 IL15 MAP2K1 PIKFYVE FES GRP CD38 FGFR3 DIRAS3 IDH2 TNFSF13B CASP7 MLEC TOP1 SLC47A1 APPL1 CRKL UCP2 IGF1R XRCC4 BTK TRPV1 CD83 RELB RCAN1 PMAIP1 SOD2 FAS SLC19A3 OPTN CFLAR RAB8B ALDH2 PTGS1 ILK MPO CCR7 CD52 CASP8 CDKN1B GZMB RPS6 CD44 SESN1 GNE ACTA2 SESN2 IL13 DAPK2 ERBB4 AIM2 NR4A1 CYP2C8 APOE MMP2 ANO1 ADORA2A FGF2 SAA2 CD68 CD80 CXCL12 TGFB3 C4B TLR8 CCL22 PRDX2 IRAK1 C4A MOG PRKCD TRAF6 KPNA1 YEATS4 OGG1 TSG101 AQP9 ITCH CRP PRL CDK9 LARS LIPE ALK NPC1 AGO2 USP14 RET KDM1A EIF2AK4 DNM1L CASP9 HBA1 PHOX2B CARS DICER1 CYP17A1 NFATC1 BACE1 HPRT1 CYP2C9 POMC EEA1 TRPA1 KIR2DL3 CDK6 TNFSF11 RECK CXCR4 TERT PARP1 MLLT3 HDAC8 HFE XBP1 TFEB PPARGC1A TRIM63 NFATC2 SYK EGF NEDD4 GBA SH3GLB1 ATG9A ELL BAK1 SP140 CD82 CALCOCO2 PIK3C3 FADD ATG12 HACE1 SPP1 UVRAG ATG3 CDC42 CD33 CLN3 BECN1 ACAT1 ORAI3 MFF RASSF1 KCNJ2 MSH6 PLA2G4A HLTF FGA HTT ANKH PINK1 SHH SMPD1 G6PD ACSL1 NBN TPP1 PSEN1 ATP6V0A1 UROD MFN2 PDGFRB FDPS SPHK1 ERCC1 XRCC6 SMAD2 NRF1 OCLN NLRP3 SNAP29 PLIN3 GHR NFE2L2 PPARA CYP11A1 ADRB1 MMP7 IGF2R MTHFR MRGPRD VAMP2 CALCA APOB NEUROD1 SP1 GLP1R TRPV5 CPM KEAP1 SIRT3 EPO GDNF PER2 HDAC4 ECE1 SIRT6 CTAG1B EWSR1 USP9X KMT2A NANOG ID4 SLC22A2 WNK2 PROM1 NF1 KRAS CBL EHMT2 CYP3A5 TSC2 PTP4A3 USH2A HLCS MAP3K5 TIGAR LRSAM1 COPS8 RBPJ TRPV4 LRWD1 SLCO1A2 TNFRSF10B CD1D SPRED2 DISC1 AKT2 BCL2L11 NOTCH3 MCOLN1 NQO2 HSF1 ZFAT TARDBP ATG7 AGGF1 LRBA MYO1C TLX3 TSLP ABCA3 ATG10 CYP2D6 ATMIN PRKAA1 GRPR IL9 ORMDL1 SLC19A1 DAPK1 RACK1 PROX1 FIS1 NMBR RAB32 SLCO1B1 EIF2AK3 ANGPTL8 BIK CAMK2G PHF23 TAS2R4 STX17 EIF4EBP1 ATG13 AMBRA1 CPT1B TAS2R3 ATG16L1 TP53BP1 ATG14 TAS2R14 TAS2R10 FBXO32 SLC38A9 VPS16 MAP1A ERBIN CNTF RHO SENP6 DHPS MRPS22 IVD RHD RAB26 ADAMTS13 EEF2K NRAS CYP2A6 BHMT NANP TFPI RNF168 RORC FBXW7 DAP CD1C CYP2C19 DROSHA UBR5 AQR IDO2 MRPS7 ADIPOR2 WWP2 IAPP UGT1A1 NPAS4 CD22 UBR2 PAK1 STK11 PRKCG MAPK9 ATP13A2 AQP8 MRPS15 ASIC3 NDUFA4L2 MT-ATP8 MRPL40 FOXP3 MFN1 SLC47A2 PRKDC SPHK2 CPQ APOA1 UBR4 SLC19A2 UBIAD1 SLC39A4 GOLPH3L CXCR1 PDCL2 LEPR HK2 CNOT2 SCN9A UBR1 NOTCH4 APAF1 TRPV3 RABGAP1 VAPA CD79A MYF5 PRDM16 KCNJ8 DEFB1 TRPC6 PGAM5 TMEM106B SIRT2 SLC30A1 DNM2 GML LUM SCN10A RPS6KB2 CCL21 DHODH SCARA3 KCNA5 FANCF MAGEA3 SLCO1B3 PDCD6IP TSC1 SESN3 Chloroquine 25 Literature-Associated Ion Channels Genes from Geneshot AutoRIF Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). CFTR P2RX4 PKD2 TRPV6 TRPM8 KCNN4 RYR2 KCNJ10 CYBB TRPC3 KCNJ11 TRPV1 ANO1 TRPA1 KCNJ2 TRPV5 TRPV4 MCOLN1 ASIC3 SCN9A TRPV3 KCNJ8 TRPC6 SCN10A KCNA5 Chloroquine Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). IL1B MAPK3 HSPA5 CTSL SQSTM1 MAP1LC3A TRIB3 DDX58 EIF2S1 TBK1 RIPK1 TLR4 TIMM9 NBR1 GABARAPL2 BAG3 HSP90AA1 FYCO1 CTSD NLRX1 RAB7A TAS2R38 TAS2R39 MAPK1 RPS6KB1 TFAM ATP6V1B2 TRIM37 BCL2L2 DEPTOR LMO7 RICTOR FNIP2 PRKAA2 UNC93B1 ATG16L2 UQCRC1 ATG4B AKAP1 LMNB1 CTSB MYO1E DDIT4 CTSZ MAVS ACTB CYCS MTOR TRIM16 LAMP1 GABARAPL1 GOLPH3 TAS2R9 TAS2R1 TAS2R16 TFE3 ULK1 ATG2A IRF7 RAB37 TLR1 CLEC7A CTSS TLR7 IRGM TLR3 MAP1LC3B EEF2 RHEB DRAM1 LAMP2 GABARAP RPL4 COX4I1 BNIP3 TP53INP1 TOMM20 ATF4 RAB9A SLC38A2 BNIP3L DDIT3 TAS2R46 TLR6 TLR9 TP53INP2 FOXO3 VMP1 ATG5 EIF2A VAMP7 CDC16 MAP4K3 TUFM RB1CC1 GLB1 MUL1 TLR2 PIKFYVE IRAK2 TICAM1 SOD2 OPTN RPS6 ZKSCAN3 SESN2 PLSCR1 TLR8 IRAK1 ORMDL3 PRKCD RUBCN TRAF6 TANK TIRAP EIF2AK4 DNM1L EEA1 WIPI2 TFEB TAX1BP1 SH3GLB1 ATG9A BAK1 CALCOCO2 PIK3C3 ATG12 WIPI1 UVRAG ATG3 CLTC BECN1 PINK1 ULK3 ZFYVE26 NRF1 IRAK4 PELI3 SNAP29 TSC2 DTYMK RAB33A TIGAR TAS2R43 MCOLN1 ATG7 ATG10 PRKAA1 EIF2AK3 BIK TAS2R4 STX17 BNIP1 ATG101 ATG4C EIF4EBP1 ATG13 RPTOR AMBRA1 WDFY3 PRR5 RAB9B DRAM2 ATG16L1 TMEM74 EVA1A ATG4A ULK2 ATG2B ZFYVE1 MAP1LC3C FUNDC1 ATG4D ATG14 TAS2R14 PCDH17 PIK3R4 EPG5 TLR10 RAB33B FBXO32 SLC38A9 MRPS22 RAB26 MRPS7 MAPK9 MRPS15 MRPL40 GOLPH3L RPS6KB2 PDCD6IP TECPR1 TAS2R5 CSN2 PPM1D NOD1 SMCR8 TAS2R13 RAB24 CPTP Chloroquine Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). TICAM2 CASP6 IL1B BCL2L1 CD14 IFNA1 HSPA5 CTSL SQSTM1 MAP1LC3A IRF3 DDX58 TBK1 RIPK1 TLR4 GABARAPL2 BAG3 IFNG IL12B NFKB1 MAPK14 UBQLN1 CTSD STAT1 TMEM173 IFNB1 RAB1A UBQLN2 CASP3 MYD88 PTK2 RPS6KB1 CAV1 BCL2 RICTOR PRDM1 BAX UNC93B1 MAN2B1 ATG16L2 UQCRC1 ATG4B AKT1 HDAC6 UNC13D CTSB DDIT4 VDAC1 LIPA SIGIRR CXCL8 FOLH1 MAVS NRDC CD300C MAPK8 MTOR CAPN1 LAMP1 GABARAPL1 GOLPH3 HIF1A CTSC TNFRSF1A ULK1 IRF7 TLR1 CTSS TLR7 CTSK TREX1 CLEC4E CASP4 NOD2 TLR3 MAP1LC3B RAC1 RHEB DRAM1 LAMP2 CTSH GABARAP EIF5A ICAM2 ATF4 RAB11A BNIP3L DDIT3 TLR6 TLR9 VMP1 ATG5 PPP3CA MAP4K3 RB1CC1 RIPK3 PRF1 TLR2 BID RIPK2 IRAK2 APPL1 PIK3R1 CHUK BTK TICAM1 IFNA2 IL12A OPTN CNPY3 CASP8 RPS6 CAST SESN2 AIM2 FANCA TLR8 IFNA17 IRAK1 CCL3 TRAF6 SARM1 CD300A IKBKG TIRAP NPC1 CASP9 EEA1 NEDD4 PRKAB1 SH3GLB1 ATG9A BAK1 PIK3C3 ATG12 UVRAG ATG3 BECN1 PINK1 NBN IRAK4 NLRP3 USP9X TRIM50 KRAS TSC2 TRDMT1 RAB7 ARR3 MCOLN1 HSF1 ATG7 ATG10 PRKAA1 DAPK1 ATG101 ATG4C EIF4EBP1 ATG13 RPTOR AMBRA1 PRR5 ATG16L1 ULK2 ATG2B MAP1LC3C FUNDC1 ATG4D ATG14 PIK3R4 TLR5 LRRC59 TLR10 VPS52 KAT2A RAB33B RPS6KB2 PDCD6IP TSC1 SESN3 NOD1 SMCR8 FUT1 MIR30B ABCB9 EMC6 BCL2L13 PRKN CTNS FGD4 MIR23A ATG9B TLR11 TLR12 WRNIP1 PLD1 RC3H1 FANCC TTI1 Chloroquine Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). TAAR1 TBK1 TAPT1 ETDB RBM41 SLC30A6 FRMD8P1 PPY2P ZNF564 SLC35A5 HIST1H4G FABP3P2 TAS2R9 OR12D3 IFNW1 TAS2R8 GPR31 ZNF780A TMEM260 ZNF597 TLR6 ZNF484 AFTPH ZBED8 ZUFSP THAP9 SPDYE1 TAS2R41 TSTD2 ZNF791 ZNF623 ZBTB6 ANKRD49 RRH ZNF223 ZNF546 TPTE2P5 TAS2R50 OR2H2 USB1 TIRAP VIPAS39 COX7BP1 YIPF4 ZNF34 XCR1 ZNF41 RAB40A RNF185 VPS54 GNRHR WASF4P GRK4 ZNF81 SEC14L1P1 TMEM168 ANKAR HNRNPLP2 ZCWPW2 AHCTF1P1 ZNF620 ZNF487 ZHX1C8ORF76 TAS2R14 PRELID1P4 WASHC2D COX6B1P3 SDCCAG3P2 RPL36P18 GAPDHP73 FTH1P14 ZNF259P1 ZNF205AS1 RRN3P2 FTH1P22 PIGHP1 GCNT7 RNFT1 SLC38A9 UBR2 UBR1 TAS2R13 HMGN2P9 ZNF175 ZNF12 FBXO4 ZNF780B USP12PX ZSCAN32 ZNF749 SLC16A12AS1 FAM45BP HPS3 SETDB2 TRIM52 RPS2P45 ZNF543 VENTXP6 TAF5LP1 API5P1 ZNF284 TRAPPC11 ZNF133 EXOC5P1 GABPB1IT1 ZNF202 ZNF627 SRGAP3AS4 ZSCAN12 TRAV6 TUBGCP5 ERVH3 SCAND2P SLC25A5P1 VCPIP1 ZNF720 ANKRD20A14P OR10G6 ZNF621 ZBTB25 ZNF510 ZNF169 ABHD17AP3 ZNF19 ZNF136 ZNF75D ZNF613 ZNF800 GIN1 OR52E5 VPS50 VHLL TOGARAM1 RSBN1L ZMYM6 RBAK ANKHD1EIF4EBP3 PRINS ZNF283 ZNF449 ZNF224 ABHD17AP4 ZNF641 TRAV261 WHAMMP3 ZCCHC4 PRMT9 PIGB ZNF32AS2 ZNF821 HMGB1P37 ZNF225 PGBD4 ZNF182 UHRF1BP1L VN1R82P TRAJ10 USP45 PSMC1P11 HEXAAS1 GSTTP1 OR2AP1 ZNF782 ZBTB8OSP1 ZNF26 SLC35B3 ZNF227 ZNF45 HNRNPA1P70 RNA5SP383 PRELID1P3 SPICE1 GUSBP8 TAS2R45 STRADA AP4E1 CRYZP1 ZNF630 PIN4P1 SNORA11C ZNF17 FAM226A SNX13 ZNF383 GOLGA1 RSC1A1 ZNF398 ZNF197 RPL23AP51 USP49 GALK2 FLYWCH1P1 GPAA1P1 ZKSCAN8 PROX2 GDAP2 TMPPE TNPO1P1 RPS24P14 ZSCAN25 Chloroquine Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). EIF3F SQSTM1 MAP1LC3A DDX58 TBK1 RIPK1 UBE2K TLR4 TIMM9 TAS2R40 ATF6 NBR1 GABARAPL2 BAG3 FYCO1 CTSD NLRX1 RAB7A TAS2R38 TAS2R39 TOMM70 RPS6KB1 TFAM BCL2L2 DEPTOR CD180 FNIP2 PRKAA2 FNBP1L UNC93B1 ATG16L2 ATG4B AKAP1 CTSB DDIT4 GADD45B CD300C MTOR TRIM16 LAMP1 GABARAPL1 TAS2R7 TAS2R9 TAS2R1 TAS2R8 TAS2R16 ULK1 ATG2A AKT1S1 IRF7 RAB37 TLR1 CTSS TLR7 AAK1 IRGM TLR3 MAP1LC3B RHEB DRAM1 LAMP2 GABARAP RPL4 COX4I1 BNIP3 TOMM20 LAMTOR1 ATF4 RAB9A BNIP3L TAS2R46 TLR6 TLR9 TP53INP2 FOXO3 ATG5 EIF2A TUFM RB1CC1 RRAGC RRAGB PPP3CB MUL1 TLR2 IRAK2 TICAM1 RRAGD CNPY3 RPS6 ZKSCAN3 SESN2 DAPK2 FFAR4 TLR8 IRAK1 ORMDL3 RUBCN TRAF6 PSMG2 TANK TMED7-TICAM2 TIRAP EEA1 WIPI2 TFEB TRIM63 TAX1BP1 TRIM54 YIPF1 SH3GLB1 ATG9A BAK1 CALCOCO2 PIK3C3 ATG12 WIPI1 TM9SF1 UVRAG ATG3 CLTC BECN1 FFAR2 PINK1 ULK3 ZFYVE26 IRAK4 PELI3 SNAP29 TSC2 PCM1 RAB33A TIGAR TAS2R43 MCOLN1 ATG7 ATG10 PRKAA1 TAS2R4 STX17 ATG101 ATG4C EIF4EBP1 ATG13 RPTOR AMBRA1 WDFY3 PRR5 RAB9B TMEM192 DRAM2 TAS2R3 ATG16L1 TMEM74 EVA1A ATG4A ULK2 ATG2B ZFYVE1 MAP1LC3C FUNDC1 ATG4D ATG14 TAS2R14 TAS2R10 PIK3R4 EPG5 TLR10 TIMM23B ZFAND5 RAB33B FBXO32 PRR5L SLC38A9 WDFY1 MAP1A COQ10B MRPS22 RAB26 EEF2K MRPS7 MRPS15 MRPL40 GOLPH3L PDCD6IP TECPR1 TAS2R5 NOD1 SMCR8 TAS2R13 RAB24 PRKN STRADA HYPK TAS2R30 WDR41 FFAR1 BCL2L2-PABPN1 RRAGA FBXO25 OVAAL Chloroquine Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Chloroquine is recognized as a top drug repurposing candidate for COVID-19, although it requires additional study before its efficacy can be concluded (e.g. Touret and de Lamballerie (2020) Of Chloroquine and COVID-19. Antiviral Research, 177). GLA FCGRT CD14 CTSL LILRB2 SLC7A7 TLR4 LYN OAS1 FKBP15 AGTRAP SIRPB2 CD4 IL17RA LILRB1 SPI1 GRB2 MTMR14 MGAT1 LCP1 NINJ1 IGSF6 PLA2G7 FTL UNC93B1 MAN2B1 ITGB2 ITGAX ALOX5 LRRC25 EMILIN2 TYMP CYBA PLEKHO2 SLC15A3 ITGAM GRN CPVL HK3 CMTM6 SLC11A1 FLVCR2 CAPG PLBD1 RAB20 LILRB5 RENBP TMEM150B IRF5 CTSZ HEXB CLEC12A GPR68 MPEG1 CD300C PLAUR FRAT2 AP5B1 HCLS1 GPR65 IL10RA IRF7 PSTPIP1 AOAH MS4A7 TLR1 LILRB4 GPR84 PIK3R5 CLEC4A CCR5 CLEC7A VAV1 FCGR2B CTSS FCER1G CD86 SIGLEC1 CCR1 CYBB CMPK2 OSCAR CLEC4E PTAFR CLEC4D LGMN TCIRG1 NFKBIE GBP2 GLIPR2 PARP12 NOD2 C5AR1 RHOG DRAM1 GNG10 LITAF FUCA1 TYROBP IFI30 TALDO1 PSAP ATP6V0B LAPTM5 RNASE6 HCK GM2A THEMIS2 NCF4 FPR2 SIGLEC7 SIGLEC9 TLR6 CYTH4 ARHGAP25 ZNFX1 ATP6V0D1 DNASE2 TLR2 CASP1 GCA TDRD7 SLC43A2 RP2 LY96 MNDA CD302 RNF19B LGALS9 MX2 VNN2 RNF149 MSRB1 RNASET2 CD53 EVI2B FCGR1B DPEP2 NCF1 CD68 STAB1 ACP5 CECR1 IL10RB IFNGR1 PRKCD PILRA NCF1C APOBR NAGK TBXAS1 SIGLEC5 LILRB3 HPS1 LILRA6 GPR132 FGR STX11 SCO2 NCF2 C19ORF38 GK FCGR3A SIGLEC14 RGS19 AQP9 HLX TNFRSF1B IFNGR2 CPPED1 ADPGK TOM1 ELL LACTB SQRDL ARPC5 ARMT1 ACSL1 PSEN1 SERTAD3 MFSD7 SLC31A2 NPL AMPD3 NLRC4 IL6R NFAM1 CMKLR1 ADGRE2 MKNK1 SLC8B1 LILRA2 CYB561A3 CYP27A1 SNAI3 CD300LB NUMB SEMA4A CTBS NRBF2 Hydroxychloroquine 64 Literature-Associated Genes from Geneshot GeneRIF Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). IL6 SFTPD IFNA1 STAT3 CYP3A4 IL17A SQSTM1 MAP1LC3A TNF CXCL10 F5 HLA-DRB1 CTSD TP53 F2 TGFB1 MX1 CD24 ITGAX ITGAM GRN LPL BIRC5 IL18 TYMS PIK3CA MTOR IL18BP CD27 TLR7 SIGLEC1 TREX1 CD19 KL TLR3 SFTPC ADAMTSL2 IL17F ABCA4 TLR9 FOXO3 MMP9 TLR2 TNFSF13B BTN3A2 KLRK1 MMP2 FCGR3A MTR TRP53 BECN1 ANKH KCNH7 NFE2L2 MTHFR KEAP1 CYP3A5 MAPK7 ABCA3 CYP2D6 RAET1E SLC19A1 CAMK2G APOA1 Hydroxychloroquine Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). IFNAR1 IL1B IL6 MAPK3 IFNA1 ABCC1 SQSTM1 IRF3 DDX58 TBK1 IL1A CXCL10 TLR4 IFITM1 GABARAPL2 IFNG NFKB1 IL4 MAPK14 TCN2 OAS1 FCGR2A CTSD STAT1 EIF2AK2 ITGA4 OASL MAT2B IFNB1 ISG15 CXCL9 CSF2 GGH MX1 MYD88 MAPK1 FBXO9 NR3C1 TPMT BCL2A1 ITGA2 CD180 SERPINB2 PRKAA2 GADD45A CCL8 ISG20 UNC93B1 ITGB2 PDIA6 ATG4B C1QA GART ITGB5 ITGAL ABCC3 ZWINT CTSB IFI44 TNFRSF17 IRF5 SHMT1 BIRC5 PPARG MERTK DPYD KIF23 MTHFD2 TYMS ABCB1 TCN1 CACNA2D2 TGFBR3 ABCC5 TGFBR2 ABCC2 LAMP1 GABARAPL1 FPGS TNFRSF1A ULK1 RSAD2 IRF7 RAD54L CD3G TLR1 IFIT1 ITGB7 CCNF STAT4 CLEC7A FCGR2B IGF2BP3 CTSS IFIT3 TLR7 OAS2 APOL6 FOLR2 IL1R2 CMPK2 IFI16 DHFR IFIH1 SFTPB IFI35 TLR3 CSF3 IRF2 LY6E MAP1LC3B IRF1 IRF9 DRAM1 SFTPA1 GABARAP IFI44L BNIP3 RPS9 BLMH BNIP3L CSF1 TNFSF4 TLR6 TNFAIP3 TLR9 NAPSA DLG2 AHCY ATG5 IL17C RB1CC1 FOLR1 VAV3 NNMT TLR2 CXCL11 IFI6 IFNL2 DDX60 DCTD RNF19B IFIT5 HERC5 GBP1 TICAM1 SOD2 IFNA2 IL18R1 CSF2RB SLC25A32 CYP2C8 TLR8 IFNGR1 CD40LG ITGA6 IRAK1 CCL7 TRAF6 TANK FGR TIRAP IGF1 TFEB TNFRSF1B MAP3K7 FBLN1 PIK3C3 ATG12 IRAK3 ATG3 SFTPA2 IL23R PDGFA SGPL1 TNFRSF11A IL6R MTHFR TGFA ABCC10 ABCA8 DTYMK NQO2 ATG7 SLC19A1 SLCO1B1 ATG16L1 MAP1LC3C TLR10 BHMT TNFRSF13B MTRR IL13RA1 ENPP1 ENOSF1 LPCAT2 BHMT2 MTHFD1 FLT3LG ERCC2 Hydroxychloroquine Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). TICAM2 IL2 IL1B IL6 MAPK3 SFTPD CD14 IFNA1 PRKCZ CCL2 CYP3A4 IL17A SQSTM1 MAP1LC3A TNF IRF3 DDX58 TBK1 IL1A TLR4 XIAP IFNG IL12B NFKB1 TCN2 OAS1 FCGR2A HLA-DRB1 BIRC2 STAT1 ABCG2 TMEM173 CXCL2 IFNB1 CD8A ISG15 CD4 CXCL9 GGH IL10 MYD88 TPMT BCL2 TNFSF10 CD180 ABCA1 UNC93B1 ITGB2 RNASEL ITGAX ITGAL ITGAM LDLR MSR1 TNFRSF17 SHMT1 GSTO1 DPYD TYMS ABCB1 CXCL8 GSTM1 TCN1 FOLH1 CD300C MAPK8 CXCL13 FPGS UMPS TNFRSF1A CXCR3 IRF7 CD28 TLR1 ULBP1 FCGR1A PTPRC CLEC7A FCGR2B CYP1A1 CYP2E1 TLR7 CD86 C3 CD19 CLEC4E DHFR IFIH1 SFTPB SOCS1 TLR3 EPHX1 MAP1LC3B IRF1 ICAM1 FOXF1 GSTP1 IRF9 JUN SFTPA1 SFTPC LAMP2 BNIP3 CYP2B6 CYP1A2 IFNL1 NOS2 TLR6 IL23A TLR9 BBC3 NQO1 ATIC ATG5 EIF2A FOLR1 HMGCR TLR2 CD40 TNFRSF13C CD38 IL32 TNFSF13B BCL10 PIK3R1 CETP CHUK BTK TICAM1 FAS IFNA2 IL12A IL7 MPO CASP8 MS4A1 CD44 CBS CYP2C8 APOE TLR8 IFNA17 IRAK1 CCL3 TRAF6 TIRAP MTR NKX2-1 CYP2C9 SYK EGF CD33 ITPA ERCC1 RAET1G RAET1L IRAK4 NFE2L2 LIPC MTHFR APOC3 APOB CHDH CYP3A5 PGP NQO2 ATG7 SLC19A1 SLCO1B1 TLR5 TLR10 VPS52 CYP2A6 BHMT CYP2C19 UGT1A1 CD22 CCL21 SLCO1B3 MTRR MTHFD1 ERCC2 MTHFS APOA5 SLC46A1 ITGAE ULBP3 LY6C1 GSTT1 NCAM1 DHFR2 ALDH1L1 RAET1D CYP3A7 KLRB1C ULBP2 FASL RFC1 GSTM3 CTH Hydroxychloroquine Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). TICAM2 TMEM202 SIRPD SLC7A7 TREM2 FCGR2A GNGT2 TMEM173 FERMT3 VSIG4 SPI1 ZC3H12D AIF1 UNC93B1 SLCO2B1 ADCY7 SH3TC1 TRPV2 PLCB2 PRAM1 PSD4 SLC15A3 SLAMF8 HCAR2 SLC11A1 GBGT1 TMEM106A ADAP2 FGD2 TMEM150B SIGLEC11 TNFAIP8L2 ADORA3 SCIMP SIGLEC16 SLC2A9 HPGDS ZMYND15 GPBAR1 SASH3 GPR65 SLC37A2 SELPLG PSTPIP1 ZBP1 AOAH SIRPB1 OCSTAMP TLR1 PLD4 RASAL3 GPR84 PIK3R5 FCGR1A SLAMF9 VAV1 FCGR2B APOBEC1 TLR7 SIGLEC1 FOLR2 GPR141 PTAFR TCIRG1 TIFA HPSE GPR35 UBA7 APOC2 GPR34 SFTPA1 CSF1R ALOX5AP HCK THEMIS2 CSF2RA FPR2 PIK3R6 SIGLEC7 TAGAP SIGLEC9 HEATR9 TLR6 TLR9 TNFSF12 TNFRSF14 RIPK3 TIFAB F10 ODF3B TNFSF8 TMEM221 TLR2 CSF3R SLC28A2 GSDMD TAPBPL TIMD4 TRIM69 TREML1 WAS SNX20 PIK3CG WDFY4 FES FPR1 F7 RAB44 VMO1 TMEM140 PIK3AP1 CSF2RB PLEK FCGR1B APBB1IP SERPINB9P1 STAB1 VNN3 RASGRP4 TLR8 TRG FUT7 PILRA ADGRE1 APOBR TBXAS1 SIGLEC5 GPR132 ARHGAP9 FGR STX11 SIGLEC14 TNFRSF1B SP140 ALDH3B1 XCR1 TREML4 TFEC GAPT SMAP2 ADCY4 ABI3 TLR5 PRELID1P4 FTH1P22 GRK5IT1 FPR3 SCARF1 TNFSF13 TAF5LP1 FLYWCH1P1 TNFRSF13B OR8T1P TNFSF12TNFSF13 CSF2RBP1 PRSS46P TREML2 FCGR1CP YWHAQP5 TOMM20P2 SMIM25 GIMAP1 RPL22P22 RNU6917P GOLGA5P1 NUTM2HP PGBD4P3 GPR82 RPL7AP64 TRIM34 GIMAP1GIMAP5 SDCBPP3 GAB3 SIGLEC22P EXOC3L4 HRH2 ADGRE4P HACD4 TRBJ16 RAB42P1 RPS26P21 HNRNPA1P69 SLC25A47P1 GGTLC4P FAM167B RNU6967P UBE2V1P9 SMPD5 S1PR4 RPL3P13 HAVCR2 RAB7B PGM5P4 SLC25A45 SIGLEC18P TP53COR1 HNRNPCP4 ADGRG5 PTGIR USP30AS1 Hydroxychloroquine 21 Predicted GPCRs Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). HCAR2 ADORA3 GPBAR1 GPR65 GPR84 GPR141 PTAFR GPR35 GPR34 FPR2 FPR1 ADGRE1 GPR132 XCR1 FPR3 GPR82 HRH2 ADGRE4P S1PR4 ADGRG5 PTGIR Hydroxychloroquine Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). IFNAR1 ABCC1 IL17A SQSTM1 IRF3 DDX58 CXCL10 TLR4 NBR1 NFKB1 TCN2 OAS1 FCGR2A STAT1 IL12RB1 ITGA4 OASL CXCL2 MAT2B IFNB1 ISG15 IL17RA CXCL9 GGH MYD88 FBXO9 TPMT CD180 CCL8 ISG20 UNC93B1 LAIR1 ATG4B ITGAX ITGAL ZWINT IFI44 IRF5 SHMT1 EPSTI1 IL18 MTHFD2 TYMS ABCB1 SIGIRR NCR3 KLRG1 ABCC5 ABCD4 GADD45B LAMP1 IRF8 GABARAPL1 IFNA13 FPGS ULK1 CXCR3 RSAD2 OAS3 CD69 CLEC4C IRF7 SLAMF7 TLR1 FCGR1A CX3CR1 IFIT1 ITGB7 CD72 CCNF CLEC7A FCGR2B IFIT3 RTP4 TLR7 OAS2 CD86 APOL6 FOLR2 DHX58 IL1R2 USP18 CMPK2 IFIT2 DHFR IFIH1 SFTPB IFI35 CCL19 TLR3 LY6E MAP1LC3B DRAM1 SFTPA1 LAMP2 GABARAP IFI44L BNIP3 IL3RA FSTL1 BNIP3L IFNL1 IL27 TLR6 IL23A TLR9 ATG5 RB1CC1 FOLR1 NNMT NCR1 EBI3 TLR2 CD40 IL15 TNFRSF13C BATF3 IRAK2 IFI6 IFNL2 LAMP3 DDX60 RNF19B GBP1 CD83 CDK17 TICAM1 SOD2 IL18R1 CNPY3 CSF2RB CCR7 CYP2C8 CD70 TLR8 CCL22 IRAK1 IFNAR2 TRAF6 TANK TMED7-TICAM2 SIGLEC14 TIRAP TFEB ATG9A PIK3C3 ATG12 UVRAG CALHM6 IRAK3 ATG3 CD33 SFTPA2 IL23R IRAK4 MTHFR ABCC10 ABCA8 IL6ST ATG7 ABCA3 ATG10 SLC19A1 ATG13 AMBRA1 DRAM2 ATG16L1 ULK2 ATG14 TLR10 TIMM23B MAP1A BHMT CD22 NOD1 SMCR8 WDR41 TNFRSF13B MTRR IL13RA1 ENOSF1 BHMT2 MTHFD1 FLT3LG ITGAE CYP3A7 ABCB5 TNFSF18 LILRA4 CLEC9A CLEC2D DNAH5 MTHFD1L ABCA5 ABCA2 CAMK2A PSMG1 MPP2 BTN2A2 ZFHX4 Hydroxychloroquine Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). FCGRT CD14 GMIP LILRB2 SLC7A7 ARRB2 LYN HLA-B KCNQ1 SIRPA OAS1 CFP HLA-A FMNL1 SIRPB2 FERMT3 CD4 IL17RA LILRB1 SPI1 STAT6 MYD88 RILP STXBP2 MGAT1 PLEKHO1 NINJ1 IGSF6 APOBEC3A UNC93B1 ARHGAP30 MAN2B1 ITGB2 LSP1 MYO1G ARHGAP4 PARP10 TMEM127 PARVG ITGAX VASP RPS6KA1 PLCB2 ALOX5 LRRC25 EMILIN2 SH3BP2 TYMP CYBA SHKBP1 PLEKHO2 MAP3K11 EHBP1L1 ADGRE5 TYK2 SLC15A3 ARAP1 HLA-E GRN HCAR2 HK3 SLC11A1 LILRB5 FGD2 IRF5 CTSZ MPEG1 CD300C STK40 BCL3 CEBPB AP5B1 OGFR ARHGAP27 ZNF710 HCLS1 IL10RA IRF7 PSTPIP1 AOAH LCP2 SIRPB1 MS4A7 TAP1 LILRB4 PIK3R5 SECTM1 CCR5 CLEC7A VAV1 FCGR2B MYO1F CTSS FCER1G OAS2 CD86 SIGLEC1 CCR1 DHX58 CYBB OSCAR PTAFR TCIRG1 NFKBIE PARP12 NOD2 IFI35 SAMHD1 C5AR1 IRF1 RHOG SIPA1 IRF9 LITAF TYROBP IFI30 PSAP LAPTM5 EHD1 HCK THEMIS2 NCF4 EFHD2 LST1 SIGLEC7 SIGLEC9 CYTH4 ARHGAP25 TNFSF12 TNFRSF14 PPP1R18 RIPK3 TAP2 TLR2 CASP1 WAS SLC43A2 RNF19B LGALS9 MX2 NAPA MOB3C GPSM3 PTPN6 RNASET2 CSF2RB CD53 DPEP2 ADAM8 NCF1 APBB1IP CD68 CECR1 TLR8 PRKCD PILRA NCF1C ADGRE1 APOBR NAGK TBXAS1 SIGLEC5 LILRB3 CD300A TNIP1 RIN3 LILRA6 LILRA5 GPR132 ARHGAP9 FGR STX11 NADK NCF2 C19ORF38 NCF1B SIGLEC14 RGS19 AQP9 DOK3 HLX TFEB TOM1 ELL STK10 RNPEPL1 ACSL1 MYO9B MFSD7 PTPRJ NPL AC018755.18 NLRC4 IL6R NFAM1 ADGRE2 ARSA SEMA4A C10ORF54 ABTB1 Hydroxychloroquine 236 Literature-Associated Genes from Geneshot AutoRIF Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). IL2 BCL2L1 IL6 DPP4 CCL2 NOX4 STAT3 CTSL IL17A SQSTM1 TNF TBK1 MME RHOA CXCL10 TLR4 CTLA4 ATF6 NBR1 LYN GABARAPL2 FURIN JAK2 XIAP HSP90AA1 SMAD3 HMOX1 AQP2 OAS1 AGPS ATM HLA-DRB1 CTSD TP53 ACE STAT1 TRAF3 ABCG2 ERBB2 BRCA1 CD7 OASL PTH TGFB1 ISG15 SRC EGFR HSPA8 CXCL9 CASP3 IL10 MX1 CXCL1 CFTR AQP5 ISG20 ABCA1 ATG4B C1QA GRN SNRNP70 TIMP1 CTSB LPL LDLR IFI44 ANXA5 CDC6 IL18 CCR2 HP LDHA TYMS CXCL8 CHI3L1 PTGS2 KLF2 KLF15 MAVS PKD1 PIK3CA MTOR SREBF1 MAF ATF3 TNFRSF11B HIF1A TFE3 ULK1 MEFV CXCR3 CD69 RAD51 TLR1 CD5 CD27 CCR5 IFIT3 TLR7 LRP8 CD86 C3 SIGLEC1 CYBB CD19 TIMELESS IFIH1 MLKL SFTPB ADAR PTGES NOD2 SOCS1 TLR3 BMPR2 LY6E MAP1LC3B TXN HPGD VEGFA SFTPA1 SFTPC LAMP2 ALDH1A1 IFI44L BNIP3 GNS GPX4 BNIP3L IL17F ABCA4 TLR6 TLR9 VIP FOXO3 HMGB1 TIMP2 ATG5 SSB LDHB FOLR1 SLCO2A1 RIPK3 MMP9 TLR2 CASP1 CD40 BID CD38 AMFR TNFSF13B CFLAR CA9 MPO CCR7 CD52 CASP8 CYP2C8 CD70 APOE MMP2 NCF1 CD68 CD80 CXCL12 C4B TLR8 CCL22 C4A PRKCD TRAF6 CRP PRL CASP9 HBA1 NFATC1 NKX2-1 KIR2DL3 TNFSF11 CXCR4 CLPP TAX1BP1 NFATC2 EGF PIK3C3 FADD ATG12 ATG3 BECN1 HLTF FGA HTT ANKH MVK BCL6 KCNH7 SMAD2 OCLN NLRP3 SNAP29 MTHFR APOB KEAP1 KRAS TSC2 USH2A SLCO1A2 ATG7 ABCA3 ATG10 CYP2D6 SLC19A1 CAMK2G ATG13 ATG16L1 RHO ADAMTS13 UBR5 CD22 UBR2 FOXP3 APOA1 UBR4 CXCR1 UBR1 CCL21 TSC1 APOA5 LMF1 ERAS LTBP1 AAAS LEP RPE65 MTA1 GPC3 Hydroxychloroquine Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). IFNAR1 IL1B ATE1 MAPK3 SFTPD IFNA1 CTSL SQSTM1 MAP1LC3A IRF3 TRIB3 DDX58 TBK1 IL1A CXCL10 IFITM3 ANXA3 ATF6 IFITM1 NBR1 GABARAPL2 BAG3 IFNG HSP90AA1 NFKB1 FYCO1 OAS1 CTSD FN1 STAT1 TRAF3 IFITM2 EIF2AK2 TMEM173 NLRX1 RAB7A OASL MOV10 IFNB1 ISG15 MX1 MAPK1 RPS6KB1 CHPT1 BCL2A1 TNFSF10 CD180 PRKAA2 ISG20 ATG16L2 ATG4B ITGAX BST2 CTSB IFI44 EPSTI1 KCNMA1 MAVS ACTB CYCS TRIM16 LAMP1 IRF8 GABARAPL1 TNK2 ULK1 ATG2A RSAD2 OAS3 IRF7 TLR1 IFIT1 LY86 CTSS IFIT3 RTP4 TLR7 OAS2 SIGLEC1 XAF1 DHX58 USP18 IFIT2 IFI16 IFIH1 STAT2 SFTPB ADAR MCOLN2 PARP12 IFI35 IRGM TLR3 LY6E MAP1LC3B IRF1 IRF9 PSMB9 DRAM1 SFTPC SERPINE2 LAMP2 GABARAP IFI44L COX4I1 BNIP3 TOMM20 CSF2RA RAB9A BNIP3L DEFA3 TRIM22 TP53INP2 VMP1 ATG5 TUFM RB1CC1 MUL1 CXCL11 TESC IFI6 DDX60 TNFSF13B MX2 IFIT5 HERC5 GBP1 SOD2 OPTN CSF2RB PLSCR1 GPR3 TLR8 TRAF6 TANK DNM1L WIPI2 XBP1 TFEB TAX1BP1 NFKB2 SH3GLB1 ATG9A BAK1 CALCOCO2 PIK3C3 SEC16A ATG12 WIPI1 UVRAG ATG3 BLOC1S1 BECN1 PINK1 ULK3 SFTPA2 PELI3 SNAP29 ABCA8 ATG7 ABCA3 ATG10 PRKAA1 EIF2AK3 STX17 BNIP1 ATG101 ATG4C ATG13 AMBRA1 WDFY3 RAB9B DRAM2 ATG16L1 EVA1A ATG4A ULK2 ATG2B ZFYVE1 MAP1LC3C FUNDC1 ATG4D ATG14 PCDH17 PIK3R4 EPG5 BLK FBXO32 UBR5 UBR2 UBR4 UBR1 RAB24 LRPPRC PCYT1B IL17RC UBR7 UBR3 HUWE1 DNAH9 Hydroxychloroquine Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). JAK1 IFNAR1 TRIM55 IL1B NR1I2 IL6 MAPK3 SFTPD CD14 IFNA1 PRKCZ STAT3 SQSTM1 MAP1LC3A IRF3 DDX58 RIPK1 TLR4 AP3B1 ANXA2 CUL1 GABARAPL2 BAG3 IFNG SIRPA NFKB1 MAPK14 OAS1 UBQLN1 STAT1 EIF2AK2 TMEM173 IFNB1 ISG15 UBQLN2 CASP3 IL10 MX1 MYD88 ITGA2 IFI27 SCGB3A1 ABCA1 UNC93B1 ATG16L2 RNASEL ATG4B C1QA AKT1 HDAC6 LPL TNFRSF17 C1QB GAPDH CENPW CXCL8 CCL4 CD300C MAPK8 MTOR CXCL13 LAMP1 WNT5A IRF8 GABARAPL1 ULK1 TLR1 FCGR1A IFIT1 CD72 CTSS IFIT3 TLR7 USP18 CD19 IFIH1 SFTPB ADAR TLR3 APOC2 MAP1LC3B FOXF1 PCBP1 DRAM1 SFTPA1 SFTPC SCGB1A1 LAMP2 CTSH GABARAP C1QBP BNIP3 EMC3 CALR RAB11A CSNK1A1 S100A10 BNIP3L APOH DDIT3 LTA TLR6 TNFAIP3 IFNA5 GPX3 HMGB1 MAGED1 VMP1 ATG5 RB1CC1 NCOA4 TLR2 GCA CD40 TRIM21 TNFRSF13C C2ORF40 BCL10 CHUK BTK TICAM1 IFNA2 BLNK SERPINA1 CNPY3 PTPN6 CASP8 APOE F11 TLR8 IFNGR1 C4A CCL3 CD209A TRAF6 CD300A TIRAP NPC1 NKX2-1 NEDD4 TRIM54 SH3GLB1 PRKCA CALCOCO2 PIK3C3 ATG12 UVRAG APOC1 ATG3 CD33 BECN1 MAP3K3 SFTPA2 KAT5 PRKD1 NFE2L2 CALCA TRIM50 TRDMT1 RAB7 ATG7 ABCA3 ATG10 PRKAA1 ATG101 ATG13 BANK1 AMBRA1 ATG16L1 ULK2 ATG2B MAP1LC3C FUNDC1 ATG14 TLR5 DCAF1 TLR10 VPS52 SERPINA1A KAT2A BLK RAB33B UBR1 CCL21 SLCO1B3 MIR30B ATG9B TLR11 TLR12 LILRA4 LRPPRC ELAVL4 KCNK10 KCNK2 KCNK4 TRIM35 PTBP1 DEFB2 PPP2CA Hydroxychloroquine Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). PIGS HECTD1 WASHC4 SNX1 TBK1 SLU7 AP3B1 TOR1AIP1 SRP54 GOLGA2 RAB8A UHRF2 RAB14 AGPS ERP44 ADAM17 HGS SLC30A7 SRP72 NUP214 TDP2 VPS39 VPS11 SBNO1 USP15 NUB1 GOLGB1 FBXO3 SLC33A1 XPA TAB2 TOR1B USP19 TYK2 UNC50 TOLLIP SLC35A5 HSD17B4 ADPRH TOPORS AR TPP2 PHF11 ADAR PSENEN HEXA VPS35 VPS26A YTHDC1 SUPT5H RAB3GAP1 UPF3A SAR1B RAB9A RAB5A WBP2 PRKAG1 TMX1 SAR1A UBE4A SNX4 SEC24B USO1 STAU1 RB1CC1 RLF SETD2 RRAGC CSK TOR1AIP2 RNF31 SPPL2A RNF139 XRCC1 VPS4B XRN1 APPL1 GFPT1 PIP4K2C HERC1 TGS1 RSF1 HPS5 RALBP1 PXK ZKSCAN3 SWT1 TRAF6 FBXL5 PEF1 THUMPD1 TADA3 EXOSC10 SCFD1 SUGT1 VPS36 SUPT20H TSG101 HBS1L USP33 TAX1BP1 TSNAX PRKAB1 FAF2 GNAI3 AP1B1 STX4 YIPF1 HMOX2 RAB5B SPG21 PITPNA EXOC2 SNW1 VIPAS39 STX18 TNFAIP1 PIK3C3 STX12 HPF1 RNF115 YIPF4 FAM192A USP8 SPATS2 PTPN2 ZFYVE26 TAOK3 PSEN1 RRP1 XPC SPG7 ANKRD17 SLC35A2 TNIP2 WASHC5 RNF216 WASF4P FAM91A1 SNX2 TRPM7 PGM3 PIK3C2A IFT57 PRKAA1 UBR1 RABGAP1 TRAPPC11 VCPIP1 STRADA RSC1A1 ZNF197 FBXO25 NUMB WDR48 RANBP10 PSMF1 GIT2 UGGT1 PHKA2 ZMYM5 SEC24A UBXN4 SHOC2 AP3M2 SAMD8 TBC1D15 STAM2 GOSR1 TRIP11 ANKLE2 SLC4A1AP GTPBP1 TAF2 PTPRA EXOC4 SCAF11 PIGG CRAMP1 AP1G1 RANBP9 TMEM179B RBM4 SUCO POGLUT1 UBXN7 SAP30BP ZBTB17 ZDHHC17 AP5M1 ZRANB1 SMU1 GBF1 SETX GOLGA5 ST13P19 PPP2R5A TTBK2 RALGAPB RABEP1 Hydroxychloroquine Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). IFNAR1 ATE1 EIF3F SQSTM1 MAP1LC3A IRF3 DDX58 TBK1 IFITM3 IFITM1 NBR1 GABARAPL2 BAG3 FYCO1 OAS1 STAT1 IFITM2 EIF2AK2 NLRX1 RAB7A OASL NEDD8 MOV10 IFNB1 ISG15 MX1 TENT5C CD180 PRKAA2 CCL8 ISG20 ATG16L2 ATG4B HDAC6 URM1 IFI44 EPSTI1 MAVS CD300C TRIM16 IFNK DVL2 LAMP1 IRF8 GABARAPL1 IFNA13 ULK1 ATG2A RSAD2 OAS3 IRF7 TLR1 IFIT1 IFIT3 RTP4 TLR7 OAS2 SIGLEC1 XAF1 DHX58 USP18 IFIT2 IFI16 AAK1 IFIH1 STAT2 TREM1 ADAR MCOLN2 PARP12 IFI35 IRGM TLR3 UBA7 LY6E MAP1LC3B IRF1 IRF9 GBP3 DRAM1 SFTPC LAMP2 GABARAP IFI44L BNIP3 TOMM20 LAMTOR1 BNIP3L IFNL1 TRIM22 TP53INP2 CHAC1 FOXO3 UBE2A UBE2S UBE2E2 VMP1 ATG5 VAMP7 TUFM MAD2L2 RB1CC1 TRIM21 CXCL11 TESC IFI6 IFNL2 DDX60 MX2 IFIT5 HERC5 GBP1 LPCAT1 LINC01184 CDK17 HCG26 ZKSCAN3 PLSCR1 TLR8 CGAS RUBCN TRAF6 PSMG2 TANK UBE2B EEA1 WIPI2 XBP1 TFEB TRIM63 TAX1BP1 GNAI3 SH3GLB1 ATG9A TRAPPC10 CALCOCO2 PIK3C3 SEC16A ATG12 WIPI1 UVRAG ATG3 BECN1 IRF2BP1 PINK1 ULK3 PLEKHM1 TREML4 SFTPA2 PELI3 SNAP29 ABCA8 RAB33A ATG7 ABCA3 ATG10 STX17 ATG101 ATG4C ATG13 AMBRA1 WDFY3 PRR5 RAB9B TMEM192 DRAM2 ATG16L1 ATG4A ULK2 ATG2B ZFYVE1 MAP1LC3C FUNDC1 ATG4D ATG14 PIK3R4 EPG5 TIMM23B RAB33B FBXO32 MAP1A COQ10B UBR5 UBR2 UBR4 UBR1 TECPR1 RAB24 PRKN PSMG1 IL17RC UBR7 UBR3 HUWE1 MATN1-AS1 PARP4 SLCO3A1 SPTLC3 FBXO11 LINC00884 Hydroxychloroquine Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Hydroxychloroquine, along with chloroquine, is a top drug repurposing candidate for COVID-19 (e.g. Colson et al. (2020) Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents, 105932(10.1016)). FCGRT DDX58 LILRB2 CXCL10 TLR4 LYN SIRPA OAS1 STAT1 TRIM25 HLA-A OASL ISG15 LILRB1 MX1 MYD88 ATP6V1B2 KMO BCL2A1 PLEKHO1 TNFSF10 NINJ1 IGSF6 APOBEC3A ISG20 FTL UNC93B1 PARP10 ITGAX EMILIN2 TYMP PLEKHO2 SLC15A3 HLA-E GRN HCAR2 SLC11A1 C3AR1 IFI44 ADPRH IRF5 CTSZ EPSTI1 MMP19 BATF2 CLEC12A SLC2A6 CD300C PLAUR CD48 RSAD2 OAS3 IL10RA IRF7 SLAMF7 LCP2 MS4A7 TAP1 LILRB4 GPR84 PIK3R5 IFIT1 CLEC4A TNIP3 CCR5 CLEC7A FCGR2B CTSS FCER1G IFIT3 RTP4 OAS2 CD86 SIGLEC1 XAF1 CD274 APOL6 CCR1 DHX58 CYBB IL1RN USP18 CMPK2 IFIT2 OSCAR CLEC4E PTAFR CLEC4D IFIH1 STAT2 PML TREM1 NFKBIE NAMPT GBP2 PARP9 PARP12 SAMD9L GCH1 NOD2 IL4I1 IFI35 PARP14 C5AR1 SP110 DTX3L IRF9 DRAM1 CTSH LITAF TYROBP IFI30 PSAP LAPTM5 EHD1 HCK THEMIS2 FPR2 SIGLEC7 TRAF1 IL27 TRIM22 SIGLEC9 CYTH4 ZNFX1 ATP6V0D1 SNX10 TLR2 CASP1 IL15RA TRIM21 TDRD7 CCRL2 CXCL11 LY96 MNDA DDX60 RNF19B C19ORF66 LGALS9 MX2 IFIT5 HERC5 DDX60L TMEM140 GBP1 PSTPIP2 RELB ETV7 NAPA APOL3 N4BP1 SOD2 MOB3C RNF149 LILRA3 CD53 PLEK PLSCR1 ADORA2A CD68 CECR1 TLR8 PILRA NCF1C ADGRE1 NAGK TBXAS1 LILRB3 TNIP1 LILRA6 GPR132 FGR STX11 NCF2 GK FCGR3A AQP9 HLX CARD16 CASP5 NFKB2 TOM1 TNFAIP8 ACOD1 LACTB SQRDL RNF13 TREML4 ACSL1 TFEC HCAR3 PSEN1 SLC31A2 NPL AMPD3 NLRC4 NUMB GPR137B FFAR3 Lopinavir Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). SLC10A2 CES2 NR1I2 CYP4F12 MVP ABCC1 CYP3A4 UGT1A7 NR1H4 SLC22A9 CYP2J2 CYP4F2 SLC28A1 SLC15A1 SULT1B1 CYP2C18 ABCG2 POR SLC23A1 PPIG AGPAT2 GGH UGT2B17 COQ10A TPMT VKORC1 CYP2F1 SLC15A2 C9ORF24 GSTA1 SLCO2B1 ABCC3 SULT1A1 CES1 SLCO4A1 SLC22A16 ABCB1 GSTM2 ABCG5 ABCC9 ZNF185 ABCF3 ABCC5 ABCC4 ABCG8 ABCF1 ABCF2 ABCC6 ABCD4 ABCC2 ABCE1 ABCG1 ACOX1 FPGS RXRA TAP1 CIDEC CYP1A1 CYP2E1 CYP7B1 HMGCS2 EPHX1 CYP4B1 FMO1 GSTP1 FNTA CYP2B6 CYP2S1 CYP1A2 SLC22A6 CPT1C CYP2A7 GSTA2 CYP7A1 CYP2A13 CYP4F3 SLC22A11 NQO1 TMEM243 SLC29A1 CYP20A1 SLCO2A1 RANGAP1 TAP2 SLC10A1 NR1I3 SLC28A2 SLC22A1 SLC27A1 CYP4F11 CYP8B1 SLC51A SLC47A1 UGT1A6 SLC28A3 CBR3 UGT2B15 CYP26A1 UGT1A8 NR0B2 UGT3A1 CYP2C8 AMPD1 SLCO5A1 RANBP2 UGT2B7 CYP2C9 PIAS1 ABCB11 GSTA4 ATP8B1 PON2 ABCB6 IPO13 DCAF5 C19ORF48 SLC35A2 CEP72 GCLC SLC22A8 SLC17A1 SLC22A13 SLC51B UGT1A10 KEAP1 SLC22A3 SLC22A2 ABCC10 CYP3A5 ABCA8 ABCA9 SLCO1A2 ABCA3 CYP2D6 SLC19A1 SLCO1B1 CYP2A6 CYP2C19 MRPS7 UGT1A1 SLC47A2 SLCO1B3 ABCB9 ENOSF1 CYP3A7 GSTM3 ABCB5 ABCA5 ABCA2 SLCO3A1 FOXA3 SLC22A7 CYP39A1 CYP2U1 CYP3A43 ABCB4 SLC22A5 ABCB8 ABCA10 RANBP1 HTR3B SULT2A1 UGT1A3 UGT1A9 IMPDH1 KIF6 ELMOD2 ABCC12 ABCC11 CYP4A11 ABCA13 TUBB1 GCSH UGT2B4 CYP4Z1 UGT1A4 CYP2W1 CYP4X1 TDRP SLCO4C1 SLCO1B7 GCLM UGT2B11 FNTB UGT1A5 PON3 OSBP2 B3GAT2 SLC27A6 ASTE1 AP1AR GSTT2B SLCO6A1 SLC22A10 RPP38 FLVCR1 MRPS26 ABCA6 GSTM4 CLINT1 Lopinavir Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). GCGR SEC16B NR1I2 GLYCTK PBLD SLC17A4 CYP3A4 SLC27A2 AADAC OTC UROC1 NR1H4 CYP4F2 GBA3 F13B SLC28A1 CYP2C18 F2 PCK1 MASP2 AFM MBL2 ENTPD5 HPN PROZ GYS2 ALDH8A1 ALB CP FMO3 CFH ADH1C C5 ASGR2 C2 HP HPR ANG ABCG5 ABCG8 ABCC6 GLYATL1 SLC2A2 EHHADH HPX HGFAC CFB PGLYRP2 KNG1 PON1 CYP2E1 C3 CPN2 ASGR1 APOF FGL1 AMBP FGG F9 ARG1 GCKR GBP7 EPHX1 PIPOX CYP2B6 MARC2 ACSM2B APOH ACSM2A AOX1 SLC38A4 HAO1 SERPINA10 FTCD PAH PROC CPN1 ITIH2 HAMP HYAL1 HABP2 SRD5A2 C8G ACOT12 MST1 SLC10A1 PLG SLC22A1 FETUB F7 RGN CYP8B1 CFHR4 ORM1 C6 C1S SERPINA6 SERPINA1 UGT2B15 SERPIND1 UPB1 CYP2C8 A1CF SLC38A3 F11 DPYS ADH6 AMDHD1 HPD ASPG CFHR1 C4A FCN2 C8B ITIH4 UGT2B7 SHBG CPB2 CYP2C9 TFR2 VTN ABCB11 ADH4 APOC1 RBP4 C4BPA FGA ITIH3 KLKB1 AKR1C4 G6PC NAT2 A1BG CYP2D6 SLCO1B1 CYP2A6 BHMT UGT1A1 SLCO1B3 BHMT2 APOA5 ADH1A SLC22A7 ABCB4 SULT2A1 UGT1A3 CYP4A11 UGT2B4 UGT1A4 ORM2 HAO2 UGT2B10 ACMSD FMO5 SERPINA4 APOC4 ANGPTL3 APCS ACSM5 SERPINC1 HGD TAT HRG PLGLB2 GLYAT PON3 SLC22A10 C8A HAAO DMGDH CFHR2 SERPINA11 SAA4 SERPINF2 AGXT CFHR5 LPA MAT1A C3P1 TDO2 SDS APOC4-APOC2 ADH1B CYP4A22 DIO1 HSD17B6 ITIH1 SLC25A47 RP5-966M1.6 GJB1 BAAT INHBC MTND4P20 LEAP2 C9 RP4-608O15.3 CFHR3 SLC17A2 F12 HSD17B13 Lopinavir 126 Literature-Associated Genes from Geneshot AutoRIF The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). NR1I2 IL6 DPP4 POU5F1 ABCC1 STAT3 CYP3A4 EGR1 TMPRSS2 FGF23 VCP TNF CXCL10 NPC1L1 ATF6 MIPEP ELAVL1 FURIN ADA HMOX1 FLT1 DDI1 RELA ACE ABCG2 PTH CD4 APP CASP3 SOX2 SLCO2B1 RNASEL LMNA ITGAM PPARG IL18 GAPDH MKI67 ABCB1 SLC2A4 ABCC4 ABCC2 SREBF1 CLU FGF4 WNT10A TRPM8 CD69 CCR5 PON1 ADIPOQ CYP2E1 SOCS3 INHBA IER3 FOS EEF2 ICAM1 VEGFA CYP2B6 VWF VCL CYP1A2 HAVCR1 TIMP2 SIRT1 MAP2 ZMPSTE24 WT1 BID CD38 RCE1 ORM1 UCP2 CETP UGT1A6 RELB IRS1 CA9 CD44 TAS2R60 DRD3 CYP2C8 ANGPT2 CD40LG PTPN1 CRP IGF1 SHBG LARS CARS BACE1 CYP2C9 PGF TNFSF11 CXCR4 XBP1 EGF ABCB11 NFE2L2 APOB FGF21 NANOG CYP3A5 SLCO1A2 AKT2 CYP2D6 SLCO1B1 CYP2A6 CYP2C19 UGT1A1 PRKDC APOA1 SLCO1B3 LEP UGT1A3 UGT1A4 ICMT SLC15A4 ANGPT1 TRO SLC29A4 KLB S100B PHF6 AEBP1 Lopinavir Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). SLC10A2 CES2 NR1I2 CYP4F12 ABCC1 CYP3A4 UGT1A7 ITGB1 NR1H4 SLC22A9 CYP2J2 CYP4F2 SLC22A18 COL4A1 FCER2 IFNG NFKB1 SLC28A1 SLC15A1 HNF4A SULT1B1 GGCX CYP2C18 FN1 ABCG2 SULT1A2 CSF2 UGT2B17 NR3C1 TPMT PROZ FZD5 VKORC1 CYP2F1 SLC15A2 KRT17 FMO3 GSTA1 ABCA1 SLCO2B1 ITGB5 LMNA ITGAL ABCC3 SULT1A1 SLC16A1 BIRC5 PPARG SLCO4A1 DPYD SLC22A16 TYMS ABCB1 ESR2 GSTM1 AKR1C3 ABCG5 ABCC9 ABCC5 ABCC4 ABCG8 ABCF1 ABCF2 ABCC6 ABCC2 GADD45B ABCE1 ABCG1 SULT2B1 SFRP4 FGF19 FGF9 GATM CYP1A1 CYP2E1 PLAU EPHX1 CYP4B1 FMO1 GSTP1 HPGD ALDH1A1 BLMH IGFBP7 CYP2B6 CYP2S1 THBS2 CYP1A2 SLC22A6 CYP2A7 OLFM4 GSTA2 CYP7A1 TNFAIP3 CYP2A13 CYP4F3 SLC22A11 NQO1 SLC29A1 CYP20A1 SLCO2A1 ZNF512 COL11A1 SLC10A1 NR1I3 SLC28A2 SLC22A1 RXRG BCL2L10 ALDH3A1 INPP1 CYP4F11 CYP8B1 IFI6 SLC51A ORM1 PDZK1 SLC47A1 SLC22A4 UGT1A6 SLC28A3 SERPINA1 PYGL UGT2B15 SLC17A3 UGT1A8 CYP2C8 TBXAS1 UGT2B7 CYP2C9 MFSD2B ABCB11 DDX54 HSD17B1 ABCB6 CEP72 PPARA SLC22A8 SLC22A13 UGT1A10 TGFA SLC22A3 SLC22A2 ABCC10 CYP3A5 ABCA8 ABCA9 SLCO1A2 ABCA3 CYP2D6 SLC19A1 SLCO1B1 CYP27A1 CYP2A6 CYP2C19 UGT1A1 SLCO1B3 ERCC2 CYP3A7 GSTM3 ABCA5 ABCA2 SLCO3A1 FOXA3 ADH1A SLC22A7 CYP39A1 CYP2U1 SLC22A12 CYP3A43 ABCB4 CYP51A1 SLC22A5 ABCB8 SULT2A1 UGT1A3 UGT1A9 IMPDH1 KIF6 NR1H3 ABCC12 ABCC11 CYP4A11 TUBB1 UGT2B4 ABCB7 UGT1A4 CYP2W1 CYP4X1 TDRP SLCO4C1 ORM2 UGT2B10 UGT1A5 LAMA4 POU2F1 SLC29A2 PLA2G2A ALOX12 AKR1C1 Lopinavir Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). JAK1 CES2 NR1I2 POU5F1 CCL2 MVP VCAM1 ABCC1 CYP3A4 UGT1A7 SLC9A3R1 NR1H4 EP300 SLC22A9 CYP2J2 CYP4F2 AP3B1 ESR1 SLC28A1 SLC15A1 HNF4A GGCX CYP2C18 ABCG2 POR EPHX2 UGT2B17 TPMT FGFR4 MCL1 ALB VKORC1 BCL2 FMO3 GSTA1 ABCA1 SLCO2B1 LMNA ABCC3 SULT1A1 LDLR MSR1 BLVRA CES1 SPRY2 DPYD SLC22A16 TYMS ABCB1 GSTM1 AKR1C3 PTGS2 PGR CDKN1A ABCC5 ABCC4 ABCG8 ABCC2 ACTB HNF1A AR FGF5 FGF1 FGF19 WNT10B MSX2 GLI2 RXRA PTPRC GZMK CYP1A1 CYP2E1 GCKR SCN1A EPHX1 AHR ETS1 TEK GSTP1 VEGFA CYB5A ALDH1A1 BNIP3 FNTA ATF4 CYP2B6 CYP1A2 LTA EGR2 SLC22A6 P2RY12 SULT1E1 CYP7A1 CYP2A13 PROC SLC22A11 NQO1 DIABLO SLCO2A1 HMGCR SRD5A2 SLC10A1 NR1I3 SLC22A1 ALDH3A1 CYP1B1 XRCC1 POU1F1 ORM1 PDZK1 P2RY1 UGT1A6 MPO UGT2B15 DRD3 UGT1A8 CYP2C8 ITGB3 FGF2 PRKCD UGT2B7 CYP17A1 CYP2C9 CXCR4 STARD7 ABCB11 ERCC5 HSD17B1 ITPA SHH NCOR2 G6PD CYP19A1 TBC1D9 ERCC1 CYP11A1 APOC3 APOB SLC22A8 UGT1A10 NAT2 FGF21 SLC22A2 CYP3A5 ABCA8 SLCO1A2 PGP BCL2L11 NQO2 FOXA2 CYP2D6 SLC19A1 SLCO1B1 CYP2A6 CYP2C19 UGT1A1 DHODH SLCO1B3 ERCC2 GSTT1 CYP3A7 GSTM3 SLCO3A1 FOXA3 OPRM1 CYP3A43 ABCB4 SULT2A1 UGT1A3 UGT1A9 UGT2B4 UGT1A4 CYP2C55 SLCO1B7 HTR6 SLCO1B2 SLCO1A1 FNTB ABCB1B ORM2 CYP3A11 NAT1 PPM1B ABCB1A UGT2B10 APCS UGT1A5 SLCO6A1 INHBC SLC29A2 SULT1A3 NODAL CALU FGF15 EDA INS1 CCL14 MCF2L2 NCOA1 Lopinavir Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). TMEM202 OR7A17 SLC5A2 GDF2 SLC17A4 OR2W1 UGT1A7 TAAR1 TINAG SSX7 UGT2A3 UROC1 OR1Q1 ANKS4B UBE2DNL OR1F2P SLC22A9 GBA3 OR1L4 UNC93A GUCA2B F13B OR2J3 TAS1R2 OR10G3 SLC28A1 TREML3P OR1C1 GPR142 PDILT TM4SF5 PTH CRYGB OR10H1 TAS2R38 OR8J1 PPY2P SLC39A5 PROZ ABCG5 ABCG8 RNA5SP334 SHC1P1 FMO9P OR1J4 OR10A3 XAGE2 GALP OR13C8 OR11A1 ADAM7 OR4F13P OR12D2 OR6C6 UGT2A2 TAS2R9 SSX4 RSU1P2 OR12D3 OR52I2 TTTY9B OR10R2 OR1E1 TAS2R8 TAAR5 FAM9A APOF FGL1 F9 ACSM2B ACSM2A HAO1 OR2A25 GJA8 SERPINA10 SRD5A2 SLC10A1 OR51D1 SLC22A1 OR7A5 TAS2R41 WFDC10B UGT1A6 SLC22A24 UGT2B15 SLC17A3 WFDC9 UGT1A8 UGT3A1 OR6K2 A1CF TAS2R50 WFDC11 OR10A2 OR2H2 UGT2B7 CPB2 SPDYC RDH16 ABCB11 OR7E37P AKR1C4 SLC17A1 TTTY4C TRPV5 GHRHR ALDH1L1AS1 AGXT2 UGT1A10 ADAM18 TRIM50 TSSK1B SMLR1 TTLL2 OR2L2 TCHHL1 SAGE1 OR8B8 RGSL1 POU6F2AS1 SAMSN1AS1 GOLGA6D TPPP2 ANGPTL8 SDC4P OR6N1 APOL5 CPS1IT1 GOLGA6B UGT1A1 GSTTP1 APOA5 SLC22A7 SULT2A1 UGT1A3 UGT1A9 UGT1A4 SLC22A25 SLCO1B7 ABCC6P1 APOC1P1 UGT2B10 AKR1C8P ACMSD ABCC6P2 SERPINA4 APOC4 ANGPTL3 SERPINA7 AKR1C6P ADORA2BP1 HORMAD2AS1 HMGB2P1 PLA2G12B GSTA7P PLGLA TAT UGT1A5 SAA2SAA4 SLC22A10 SERPINA11 OR3A1 OR10Q1 OR2A14 GAGE2B UGT2A1 OR14A16 HEPN1 GAGE2C PHF2P1 AIMP1P2 GNGT1 FAM99A TRBV13 OR6W1P OR6C70 OR6C75 OR10G2 OR2K2 GLTPD2 OR56A4 OR6B1 OR52H1 CSAG2 OR11H4 OR52N1 OR4D2 RPL17P11 F10AS1 OCM2 VN1R10P HNF4AAS1 UGT1A2P FAM83AAS1 OR2A1 APOA1AS NXF5 SSX3 GAGE2E RPSAP70 Lopinavir 53 Predicted GPCRs Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). OR7A17 OR2W1 TAAR1 OR1Q1 OR1F2P OR1L4 OR2J3 TAS1R2 OR10G3 OR1C1 GPR142 OR10H1 TAS2R38 OR8J1 OR1J4 OR10A3 OR13C8 OR11A1 OR12D2 OR6C6 TAS2R9 OR12D3 OR52I2 OR10R2 OR1E1 TAS2R8 TAAR5 OR2A25 OR51D1 OR7A5 TAS2R41 OR6K2 TAS2R50 OR10A2 OR2H2 GHRHR OR2L2 OR8B8 OR6N1 OR3A1 OR10Q1 OR2A14 OR14A16 OR6C70 OR6C75 OR10G2 OR2K2 OR56A4 OR6B1 OR52H1 OR11H4 OR52N1 OR4D2 Lopinavir Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). SLC10A2 CES2 NR1I2 CYP4F12 MVP ABCC1 CYP3A4 UGT1A7 NR1H4 SLC22A9 CYP2J2 CYP4F2 SLC22A18 SLC28A1 SLC15A1 HNF4A SULT1B1 GGCX CYP2C18 ABCG2 POR SLC23A1 SULT1A2 PPIG UGT2B17 TPMT FZD5 VKORC1 CYP2F1 SLC15A2 FMO3 GSTA1 ABCA1 SLCO2B1 ABCC3 SULT1A1 SLC16A1 BIRC5 CES1 SLCO4A1 DPYD SLC22A16 ABCB1 ABCG5 ABCC9 KLF10 ABCF3 ABCC5 ABCC4 ABCG8 ABCF1 ABCF2 ABCC6 SLC2A5 ABCC2 ABCG1 HNF1A PROM2 WNT16 FGF19 SPRY3 GATM TAP1 CYP1A1 CYP2E1 CYP7B1 EPHX1 CYP4B1 FMO1 GSTP1 HPGD CYP2B6 CYP2S1 CYP1A2 SLC22A6 AOX1 CYP2A7 GSTA2 CYP7A1 CYP2A13 FILIP1L CYP4F3 SLC22A11 NQO1 SLC29A1 CYP20A1 SLCO2A1 TAP2 SLC10A1 NR1I3 SLC28A2 SLC22A1 ALDH3A1 INPP1 RCE1 CYP4F11 CYP8B1 VNN1 IFI6 SLC51A PDZK1 SLC47A1 SLC22A4 LAMC2 UGT1A6 SLC28A3 UGT2B15 SLC17A3 UGT1A8 NR0B2 UGT3A1 CYP2C8 SLC16A10 UGT3A2 SLCO5A1 UGT2B7 CYP2C9 MFSD2B ABCB11 GSTA4 ATP8B1 HOXB6 DCAF5 C19ORF48 SLC35A2 CEP72 SLC22A8 SLC17A1 SLC22A13 SLC51B UGT1A10 NAT2 FGF21 SLC22A3 SLC22A2 ABCC10 CYP3A5 ABCA8 ABCA9 SLCO1A2 ABCA3 CYP2D6 SLC19A1 SLCO1B1 CYP2A6 CYP2C19 MRPS7 UGT1A1 SLC47A2 SLCO1B3 CYP3A7 GSTM3 ABCB5 ABCA5 ABCA2 SLCO3A1 FOXA3 SLC22A7 CYP39A1 CYP2U1 SLC22A12 CYP3A43 ABCB4 CYP51A1 SLC22A5 ABCB8 SULT2A1 UGT1A3 UGT1A9 KIF6 NR1H3 ABCC12 ABCC11 CYP4A11 UGT2B4 UGT1A4 CYP2W1 CYP4X1 TDRP SLCO4C1 SLCO1B7 UGT2B10 UGT1A5 OSBP2 B3GAT2 AP1AR GSTT2B SLCO6A1 SLC22A10 ABCA6 GSTM4 CLINT1 AEBP1 LAMA4 SLC29A2 GUSB SULT1C2 TGIF1 COL5A1 OR51B5 Lopinavir Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity The HIV antiviral lopinavir is an inhibitor of the HIV-1 protease enzyme, and some evidence supports its use to treat COVID-19 (e.g. Liu et al. (2020) Patients of COVID-19 may benefit from sustained lopinavir-combined regimen... Int J Infect Dis). GCGR SEC16B NR1I2 GLYCTK PBLD SLC17A4 CYP3A4 SLC27A2 AADAC OTC UROC1 NR1H4 CYP4F2 F13B SLC28A1 CYP2C18 F2 PCK1 MASP2 AFM MBL2 ENTPD5 HPN PROZ GYS2 ALDH8A1 ALB CP FMO3 CFH ADH1C C5 ASGR2 C2 HP HPR ANG ABCG5 ABCG8 ABCC6 GLYATL1 SLC2A2 EHHADH HPX HGFAC CFB PGLYRP2 KNG1 PON1 CYP2E1 C3 CPN2 ASGR1 APOF FGL1 AMBP FGG F9 ARG1 GCKR GBP7 PIPOX CYP2B6 MARC2 ACSM2B APOH ACSM2A AOX1 SLC38A4 HAO1 CYP2A7 GC SERPINA10 FTCD PAH PROC CPN1 ITIH2 HAMP HYAL1 HABP2 MLXIPL SRD5A2 C8G ACOT12 MST1 SLC10A1 PLG SLC22A1 FETUB F7 RGN CYP8B1 CFHR4 ORM1 C6 SERPINA1 UGT2B15 SERPIND1 UPB1 CYP2C8 A1CF SLC38A3 F11 DPYS ADH6 HPD ASPG CFHR1 C4A FCN2 C8B ITIH4 UGT2B7 CPB2 CYP2C9 AKR1D1 TFR2 VTN RDH16 ABCB11 ADH4 APOC1 RBP4 C4BPA FGA ITIH3 KLKB1 AKR1C4 G6PC NAT2 A1BG TTPA CYP2D6 SLCO1B1 CYP2A6 BHMT UGT1A1 BHMT2 APOA5 ADH1A SLC22A7 ABCB4 SULT2A1 UGT1A3 CYP4A11 UGT2B4 UGT1A4 ORM2 HAO2 UGT2B10 ACMSD FMO5 SERPINA4 APOC4 ANGPTL3 APCS SLC27A5 ACSM5 SERPINC1 HGD TAT HRG PLGLB2 GLYAT PON3 SLC22A10 C8A HAAO DMGDH CFHR2 SERPINA11 SAA4 SERPINF2 AGXT CFHR5 LPA MAT1A C3P1 TDO2 SDS APOC4-APOC2 CYP4A22 DIO1 HSD17B6 ITIH1 SLC25A47 RP5-966M1.6 GJB1 BAAT INHBC MTND4P20 LEAP2 C9 RP4-608O15.3 CFHR3 SLC17A2 F12 HSD17B13 LECT2 Ritonavir 232 Literature-Associated Genes from Geneshot AutoRIF Ritonavir, often combined with lopinavir, is an antiretroviral drug used to treat HIV & AIDS; it is being investigated to treat COVID-19 (e.g. Cao et al. (2020) A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19, New Eng J Med). CD209 BCL2L1 SLC5A2 NR1I2 IL6 HSP90AB1 DPP4 CCL2 CD34 ABCC1 STAT3 CYP3A4 UGT1A7 TMPRSS2 VDR VCP TNF CXCL10 TLR4 CYP2J2 ATF6 ABL1 MIPEP ELAVL1 FURIN ADA HMOX1 FLT1 DDI1 TP53 RELA ACE ABCG2 PTH NOS3 TGFB1 SRC AGPAT2 APP SCARB1 CASP3 IL10 CLDN10 SLC2A1 CEACAM5 CCL8 LCN2 ABCA1 CCND1 SLCO2B1 AKT1 CEBPA CES1 CD163 PPARG IL18 GAPDH CCR2 MKI67 CCR3 ABCB1 NOG IGFBP3 SLC2A4 CDKN1A MYC NOTCH1 ABCC4 ABCC2 SLC2A8 ABCG1 INS CYP24A1 MAPK8 MTOR SREBF1 CLU FGF4 WNT3A WNT5A WNT5B DCK TNFRSF11B TRPM8 CD69 CCR5 PON1 FABP4 ADIPOQ CIDEC RETN CIDEA CYP1A1 CFD PLIN1 CYP2E1 CD86 LIPG FOS DUSP1 ICAM1 TJP2 VEGFA PLIN2 PDE5A SOD1 KLHDC3 CYP2B6 VWF FASN DLK1 CYP1A2 IL16 SLC22A6 GFAP P2RY12 CCND2 CYP7A1 FUS SLC2A11 IRS2 SLC22A11 HMGB1 HSD17B2 CDK4 SIRT1 PIR MAP2 ZMPSTE24 WT1 TLR2 CASP1 BID SLC22A1 CTSE CD38 PCSK9 ORM1 ADRB2 SLC47A1 UCP2 CETP UGT1A6 HDX RELB NCEH1 SOD2 IRS1 FAS CA9 MPO CCR7 CASP8 CD44 UGT2B15 TAS2R60 DRD3 CYP2C8 APOE ANGPT2 CD40LG ITGA6 PTPN1 TRAF6 CRP IGF1 PRL UGT2B7 SHBG NPC1 CARS KIT BACE1 CYP2C9 PGF POMC TNFSF11 CXCR4 XBP1 EGF ABCB11 CITED2 LOR RBP4 ITPA LBP SMAD2 OCLN PDE3B NFE2L2 LIPC APOC3 APOB SLC17A1 G6PC FGF21 CRH ID4 SLC22A2 CYP3A5 SLCO1A2 AKT2 CYP2D6 SLCO1B1 CYP27A1 CYP2A6 CYP2C19 UGT1A1 PRKDC APOA1 NOTCH4 SLCO1B3 APOA5 CYP3A7 ERAS LEP SLCO3A1 SLC22A7 CYP3A43 UGT1A3 UGT1A9 NR1H3 UGT1A4 SLCO4C1 ANGPT1 KLB S100B AKR1C1 ACSS2 CYP2R1 CYP27B1 MLANA Ritonavir Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Ritonavir, often combined with lopinavir, is an antiretroviral drug used to treat HIV & AIDS; it is being investigated to treat COVID-19 (e.g. Cao et al. (2020) A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19, New Eng J Med). SLC10A2 CES2 NR1I2 CYP4F12 SLC17A4 ABCC1 CYP3A4 UGT1A7 NR1H4 SLC22A9 CYP2J2 CYP4F2 SLC22A18 GGT1 SLC28A1 SLC15A1 HNF4A SULT1B1 GGCX CYP2C18 ABCG2 SULT1A2 EPHX2 AGPAT2 UGT2B17 NR3C1 TPMT PROZ VKORC1 CYP2F1 SLC16A9 SLC15A2 FMO3 PRKAA2 SLC2A1 GSTA1 ABCA1 SLCO2B1 ABCC3 SULT1A1 SLC16A1 CES1 PPARG SLCO4A1 DPYD SLC22A16 TYMS ABCB1 ESR2 GSTM1 ABCG5 ABCC9 SLC2A9 SLC2A3 ABCC5 ABCC4 ABCG8 ABCF2 ABCC6 SLC2A5 ABCC2 CYP4V2 ABCG1 HNF1A CYP24A1 SULT2B1 SLC34A1 RXRA GATM CIDEC CYP1A1 CYP2E1 HMGCS2 EPHX1 CYP4B1 FMO1 R3HDM2 GSTP1 ALDH1A1 BLMH CYP2B6 CYP2S1 ACYP2 CYP1A2 SLC22A6 CYP2A7 GSTA2 SULT1E1 CYP7A1 CYP2A13 CYP4F3 SLC22A11 CPLX1 SLC29A1 CYP20A1 SLCO2A1 SLC10A1 NR1I3 SLC22A1 ALDH3A1 INPP1 CYP4F11 CYP8B1 SLC51A ORM1 PDZK1 SLC47A1 SLC22A4 UGT1A6 SLC28A3 NCEH1 CBR3 UGT2B15 CYP26A1 SLC17A3 UGT1A8 CYP2C8 SLC31A1 TBXAS1 UGT2B7 LIPE CYP17A1 CYP2C9 PPARGC1A NR1H2 CES3 ABCB11 GSTA4 HSD17B1 ABCB6 PPARD LRP2 CEP72 PPARA SLC22A8 SLC17A1 SLC22A13 UGT1A10 CMBL SLC22A3 SLC22A2 SLC2A12 ABCC10 CYP3A5 ABCA8 ABCA9 SLCO1A2 NQO2 CYP2D6 PRKAA1 SLC19A1 SLCO1B1 CYP27A1 CYP2A6 CYP2C19 UGT1A1 SLC47A2 SLCO1B3 ERCC2 CYP3A7 GSTM3 ABCA5 ABCA2 SLCO3A1 FOXA3 ADH1A SLC22A7 CYP39A1 CYP2U1 SLC22A12 CYP3A43 ABCB4 CYP51A1 SLC22A5 ABCB8 SULT2A1 UGT1A3 UGT1A9 IMPDH1 NR1H3 ABCC12 ABCC11 CYP4A11 TUBB1 UGT2B4 ABCB7 CYP4Z1 UGT1A4 CYP2W1 CYP4X1 SLCO4C1 ORM2 UGT2B10 UGT1A5 CYP4A22 SLC29A2 PLA2G2A CYP2R1 RFX3 MAP3K2 Ritonavir Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Ritonavir, often combined with lopinavir, is an antiretroviral drug used to treat HIV & AIDS; it is being investigated to treat COVID-19 (e.g. Cao et al. (2020) A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19, New Eng J Med). CES2 NR1I2 POU5F1 MVP ABCC1 ANPEP CYP3A4 UGT1A7 SLC9A3R1 NR1H4 SLC22A9 CYP2J2 CYP4F2 SLC28A1 HNF4A GGCX CYP2C18 ABCG2 POR EPHX2 UGT2B17 TPMT VKORC1 CYP2F1 SLC16A9 FMO3 SLC2A1 GSTA1 ABCA1 SLCO2B1 RNASEL SLC3A2 HK1 HK3 ABCC3 SULT1A1 LPL MSR1 BLVRA CES1 PPARG SLCO4A1 DPYD SLC22A16 TYMS ABCB1 GSTM1 SLC2A4 SLC2A6 SLC2A9 SLC2A3 ABCC5 ABCC4 ABCG8 ABCC2 SLC2A8 SLC2A2 HNF1A INS AR SLC7A5 RXRA PON1 CYP1A1 CYP2E1 SLC7A8 GCKR SCN1A EPHX1 AHR CYP4B1 DUSP1 R3HDM2 GSTP1 CYB5A ALDH1A1 CYP2B6 POU2F2 CYP1A2 SLC22A6 P2RY12 SULT1E1 CYP7A1 CYP2A13 SLC2A11 BHLHE40 SLC22A11 NQO1 SLC29A1 SLCO2A1 HMGCR SRD5A2 SLC10A1 NR1I3 SLC22A1 ALDH3A1 CYP1B1 XRCC1 ORM1 PDZK1 SLC47A1 SLC22A4 P2RY1 UGT1A6 UGT2B15 KBTBD3 SLC17A3 DRD3 UGT1A8 CYP2C8 APOE SLC16A10 SLCO5A1 SLC31A1 UGT2B7 CYP17A1 CYP2C9 PPARGC1A RAB4B ABCB11 ERCC5 SGK2 ITPA NCOR2 G6PD CYP19A1 TBC1D9 ERCC1 PPARA LIPC CYP11A1 ADRB1 SP1 SLC22A8 SLC17A1 SLC22A13 UGT1A10 NAT2 RREB1 SLC22A3 SLC22A2 SLC2A12 CYP3A5 ABCA8 SLCO1A2 PGP NQO2 FOXA2 CYP2D6 SLC19A1 SLCO1B1 CYP2A6 CYP2C19 UGT1A1 SLC47A2 DHODH SLCO1B3 ERCC2 GSTT1 CYP3A7 GSTM3 GIT2 SLCO3A1 FOXA3 SLC22A7 OPRM1 SLC22A12 CYP3A43 ABCB4 SULT2A1 UGT1A3 UGT1A9 CYP4A11 UGT2B4 UGT1A4 CYP2C55 SLCO1B7 HTR6 SLCO1B2 UGT2B11 SLCO1A1 ABCB1B ORM2 CYP3A11 SLC16A4 NAT1 PPM1B ABCB1A UGT2B10 UGT1A5 SLCO6A1 INHBC POU2F1 SULT1A3 CALU NCOA1 CARMIL1 STX4A SLC16A2 SLCO1C1 Ritonavir Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Ritonavir, often combined with lopinavir, is an antiretroviral drug used to treat HIV & AIDS; it is being investigated to treat COVID-19 (e.g. Cao et al. (2020) A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19, New Eng J Med). ERICH4 OR7A17 SLC5A2 OR8D2 SLC17A4 OR2W1 UGT1A7 UGT2A3 UROC1 OR1Q1 ANKS4B UBE2DNL OR1F2P SLC22A9 WFDC10A GBA3 OR1L4 UNC93A GUCA2B F13B OR3A3 OR2J3 OR10G3 SLC28A1 OR10H2 PDILT OR10H1 TAS2R38 AFM WFDC6 SEMG2 OR8J1 PPY2P SLC39A5 PROZ GYS2 ABCG5 ABCG8 GLYATL1 SLC2A2 RNA5SP334 SLC34A1 ALDH1L1AS2 FMO9P OR4F4 OR10A3 XAGE2 HIST1H4G TCP10 OR13C8 OR5AK4P OR11A1 OR4F13P FABP3P2 OR12D2 OR6C6 OR2A5 OR2B3 OR5K1 UGT2A2 TAS2R9 RSU1P2 OR12D3 TTTY9B TAS2R1 OR1E1 TAS2R8 TTTY6B OR4L1 OR10C1 TMEM207 OR1L6 FAM170BAS1 GSTA5 APOF ACSM2B SLC22A6 ACSM2A HAO1 OR4S1 OR2A25 SERPINA10 FTCD SRD5A2 ACOT12 SLC10A1 OR51D1 SLC22A1 UGT2B28 UGT1A6 SLC22A24 SERPINA6 UGT2B15 SLC17A3 UGT1A8 UGT3A1 A1CF OR10A2 OR2H2 FCN2 UGT2B7 CPB2 AKR1D1 GGT2 RDH16 ABCB11 OR7E62P OR2H1 AKR1C4 SLC17A1 TRPV5 ALDH1L1AS1 SLC7A13 SLC22A13 AGXT2 SLC51B UGT1A10 G6PC FAM9B TSSK1B SMLR1 POU6F2AS1 AOX3PAOX2P GOLGA6D TPPP2 ANGPTL8 SDC4P OR6N1 APOL5 OR2Y1 CPS1IT1 GOLGA6B UGT1A1 APOA5 GGTLC4P SLC22A7 SULT2A1 UGT1A3 UGT1A9 UGT2B4 UGT1A4 SLC22A25 SLCO1B7 HAO2 ABCC6P1 APOC1P1 TTC36 OR6C2 UGT2B10 AKR1C8P HAO2IT1 ACMSD ABCC6P2 SERPINA4 APOC4 ANGPTL3 SERPINA7 AKR1C6P ADORA2BP1 HORMAD2AS1 ACSM5 PLA2G12B GSTA7P PLGLA TAT UGT1A5 SAA2SAA4 GLYAT SLC22A10 SERPINA11 OR10Q1 OR2A14 UGT2A1 OR14A16 HEPN1 FAM99A OR6C75 OR2K2 OR56A4 HNF4AAS1 APOA1AS RPSAP70 TUSC8 SMUG1P1 SCGB1D4 RPL17P3 ERVH6 OR4K17 PRAMEF10 OR4Q3 OR1L1 AQP7P3 FOLH1B SMIM2 OR8B12 APOC4APOC2 UPP2IT1 OR8B3 SLAMF6P1 ZSCAN5C Ritonavir Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Ritonavir, often combined with lopinavir, is an antiretroviral drug used to treat HIV & AIDS; it is being investigated to treat COVID-19 (e.g. Cao et al. (2020) A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19, New Eng J Med). SLC10A2 CES2 NR1I2 CYP4F12 SLC17A4 ABCC1 CYP3A4 UGT1A7 SLC2A7 HNF4G NR1H4 SLC22A9 CYP2J2 CYP4F2 SLC22A18 SLC5A1 SLC28A1 SLC15A1 HNF4A SULT1B1 GGCX CYP2C18 ABCG2 POR SLC23A1 SULT1A2 PPIG SLC5A12 UGT2B17 TPMT VKORC1 CYP2F1 SLC16A9 SLC15A2 FMO3 PRKAA2 SLC2A1 SLC16A7 GSTA1 SLCO2B1 SLC3A2 ABCC3 SULT1A1 SLC16A1 CES1 SLCO4A1 DPYD SLC22A16 ABCB1 ABCG5 ABCC9 SLC2A6 SLC2A9 SLC2A3 ABCC5 ABCC4 ABCG8 ABCC6 SLC2A5 ABCC2 ABCG1 SLC2A2 BCAS3 SLC34A1 SLC29A3 CYP1A1 CYP2E1 CYP7B1 HMGCS2 EPHX1 CYP4B1 FMO1 CYP2B6 CYP2S1 ACYP2 CYP46A1 CYP1A2 SLC22A6 AOX1 CYP2A7 GSTA2 CYP7A1 CYP2A13 CYP4F3 SLC22A11 SLC29A1 CYP20A1 SLCO2A1 TAP2 SLC10A1 NR1I3 SLC28A2 SLC22A1 ALDH3A1 CYP4F11 CYP8B1 SLC51A PDZK1 SLC47A1 SLC22A4 UGT1A6 SLC28A3 UGT2B15 CYP26A1 SLC17A3 UGT1A8 NR0B2 UGT3A1 CYP2C8 SLC16A10 ABCA12 UGT3A2 SLCO5A1 SLC31A1 UGT2B7 CYP2C9 ABCB11 GSTA4 ATP8B1 ALPK1 C19ORF48 SLC35A2 CEP72 SLC13A3 SLC22A8 SLC17A1 SLC22A13 SLC51B UGT1A10 NAT2 SLC22A3 SLC22A2 SLC2A12 ABCC10 CYP3A5 ABCA8 SLCO1A2 NQO2 ABCA3 CYP2D6 SLC19A1 SLCO1B1 CYP2A6 CYP2C19 MRPS7 UGT1A1 SLC47A2 SLCO1B3 CYP3A7 GSTM3 ABCA5 ABCA2 SLCO3A1 FOXA3 SLC22A7 CYP39A1 CYP2U1 SLC22A12 CYP3A43 ABCB4 CYP51A1 SLC22A5 ABCB8 SULT2A1 UGT1A3 UGT1A9 NR1H3 ABCC12 ABCC11 CYP4A11 UGT2B4 CYP4Z1 UGT1A4 CYP2W1 CYP4X1 SLCO4C1 SLCO1B7 UGT2B10 UGT1A5 OSBP2 B3GAT2 SLC27A6 AP1AR GSTT2B SLCO6A1 SLC22A10 GSTM4 CLINT1 CYP4A22 SLC29A4 SLC29A2 SULT1C2 CYP2R1 CYP27B1 SLC2A14 RFX3 CARMIL1 NIPAL1 SULT1C4 SLC22A15 Ritonavir Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Ritonavir, often combined with lopinavir, is an antiretroviral drug used to treat HIV & AIDS; it is being investigated to treat COVID-19 (e.g. Cao et al. (2020) A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19, New Eng J Med). GCGR SEC16B NR1I2 GLYCTK PBLD SLC17A4 CYP3A4 SLC27A2 AADAC OTC UROC1 NR1H4 CYP4F2 F13B SLC28A1 ACAA1 CYP2C18 TMEM176A F2 PCK1 MASP2 AFM MBL2 ENTPD5 HPN METTL7A PROZ GYS2 ALDH8A1 ALB CP FMO3 CFH ADH1C SHMT1 ASGR2 C2 HP HPR ANG ABCG5 ABCG8 ABCC6 GLYATL1 SLC2A2 EHHADH HPX HGFAC PGLYRP2 KNG1 PON1 CYP2E1 C3 CPN2 ASGR1 APOF FGL1 AMBP FGG F9 ARG1 GCKR GBP7 EPHX1 PIPOX CYP2B6 MARC2 ACSM2B APOH ACSM2A AOX1 SLC38A4 HAO1 SERPINA10 FTCD PAH PROC HAMP HYAL1 HABP2 SRD5A2 C8G ACOT12 SLC10A1 PLG SLC22A1 FETUB F7 RGN CYP8B1 CFHR4 ORM1 C6 SERPINA1 UGT2B15 SERPIND1 UPB1 CYP2C8 A1CF SLC38A3 F11 DPYS ADH6 HPD ASPG CFHR1 C4A FCN2 C8B ITIH4 UGT2B7 CPB2 CYP2C9 TFR2 VTN RDH16 ABCB11 ADH4 APOC1 ECHDC2 RBP4 C4BPA FGA ITIH3 KLKB1 AKR1C4 G6PC NAT2 A1BG TTPA CYP2D6 SLCO1B1 CYP2A6 BHMT UGT1A1 BHMT2 APOA5 ALDH1L1 ADH1A SLC22A7 ABCB4 SULT2A1 UGT1A3 CYP4A11 UGT2B4 UGT1A4 ORM2 HAO2 UGT2B10 ACMSD FMO5 SERPINA4 APOC4 ANGPTL3 APCS SLC27A5 ACSM5 SERPINC1 HGD TAT HRG PLGLB2 GLYAT PON3 SLC22A10 C8A HAAO DMGDH CFHR2 SERPINA11 SAA4 SERPINF2 AGXT CFHR5 LPA MAT1A C3P1 TDO2 SDS APOC4-APOC2 CYP4A22 DIO1 HSD17B6 ITIH1 SLC25A47 RP5-966M1.6 GJB1 BAAT INHBC MTND4P20 LEAP2 C9 RP4-608O15.3 CFHR3 SLC17A2 F12 HSD17B13 LECT2 RIDA DAO Daunorubicin Top 200 Predicted Genes from Geneshot GeneRIF via AutoRIF Co-Occurrence Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). IMPDH2 CES2 BCL2L1 EEF1A1 MVP ABCC1 SUMO2 KPNA2 UBE2D3 CCND3 SLC22A18 CENPF ESR1 MAPK14 SLC28A1 ATM TP53 BIRC2 FN1 ABCG2 NT5C GGH TOP2B CHEK2 BCL2 BCL2L2 RARB GADD45A KRT19 CCND1 BAX SLCO2B1 STMN1 ABCC3 PLK1 SULT1A1 MYBL2 TOP2A CCNA2 LMNB1 CCNB2 UBE2C AURKB E2F2 HMMR MCM2 CDC25A AURKA RRM2 CDK1 CDC6 BIRC5 BCAT1 TP53I3 SLCO4A1 CDKN2B CCNB1 CBR1 DPYD HJURP TTK MKI67 SLC22A16 TYMS ABCB1 YES1 ITGB8 AKR1C3 CDKN1C ABCC9 MYC ABCF3 ABCC5 ABCC4 ABCF1 ABCF2 ABCC6 ABCD4 ABCC2 B4GALT6 MYCL CCNE1 ITGB4 SULT2B1 RARG FPGS UMPS CCNA1 RAD54L HELLS NUSAP1 MELK H2AFX DEPDC1 CCNF CENPE XAF1 CCNE2 NUFIP1 AKR1A1 GSTP1 FABP5 BNIP3 RBBP4 NCF4 BNIP3L BIRC8 GSTA2 CCND2 BBC3 SERTAD1 RRM1 SLC29A1 PTTG1 RUVBL1 ABCB10 RUVBL2 ZMAT3 ZNF385B TRA2B FEN1 SLC22A1 XRCC1 DCTD TOP1 SLC47A1 SLC28A3 CBR3 UGT2B15 TWIST1 TNFRSF10D TUBB3 GAL3ST1 TP73 SKP2 MYCN CASP9 MDM4 CDK6 USP5 BAK1 ABCB11 ASAH1 CMPK1 GSTA4 ST3GAL5 NT5C2 BTG3 ABCB6 PTCH2 E2F4 MAP4 CHFR ERCC1 ITGA3 SLC22A8 E2F3 ABCC10 CYP3A5 ABCA8 DTYMK CCNG2 SLCO1A2 ABCA3 SLC19A1 DAPK1 SLCO1B1 FBXW7 UGT1A1 SLCO1B3 TTI1 ERCC2 GSTM3 ABCB5 ABCA5 ABCA2 SLCO3A1 SPTLC3 SLC22A7 CYP2U1 ABCB4 ABCB8 ABCC12 ABCC11 UGT2B4 SLC5A6 AKR1C2 AKR1C1 RRM2B CCNG1 NDN TFDP1 LIN9 RASSF2 MTF1 TTI2 PSMA5 TACC1 ILKAP CDKN2D Daunorubicin Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). RPS27A CES2 BCL2L1 BIRC3 RB1 MVP ABCC1 CYP3A4 SUMO2 PTEN HRAS RCHY1 CCND3 EP300 AATF ELAVL1 NF2 RUNX1 XIAP HSP90AA1 NFKB1 MAPK14 ATM TP53 BIRC2 ABCG2 SFN ERBB2 NEDD8 SRC EGFR CASP3 CDK2 STAT6 TOP2B EI24 MCL1 CHEK2 BCL2 MECOM TP63 RPL23 GADD45A RPL11 RPS14 CCND1 MDM2 BAX SLCO2B1 AKT1 ABCC3 DDB1 PLK1 MYBL2 TOP2A CCNA2 EZH2 GTSE1 AURKB E2F2 FLT3 CDC25A AURKA RRM2 CDK1 CDC6 E2F1 BIRC5 CDKN2B CCNB1 MKI67 DTL TYMS GLI1 ABCB1 CDKN1C CDKN1A ATR MYC ABCC5 ABCC4 ABCC2 CYCS CCNE1 MAPK8 FOXM1 CASP2 CDC25C CHEK1 HELLS PBK H2AFX MAD2L1 XAF1 PML PIM1 YBX1 GSTP1 RPL5 RPL26 TP53INP1 CYP2B6 CSNK1A1 RASSF5 CCND2 E2F6 CDKN2AIP BBC3 FOXO3 NQO1 LAMTOR5 COPS5 PSMD10 PCNA HDAC1 DIABLO CDK4 DDB2 RUVBL2 CASP7 IGF1R PMAIP1 CBR3 CFLAR CASP8 CDKN1B BMF SALL2 TUBB3 TP73 SIAH1 SKP2 PSMD9 MYCN CASP9 CREB1 MDM4 CDK6 PARP1 EGF BAK1 TRP53 COPS6 NFYB HNRNPD SMPD3 POLR2A BCL6 NBN HNRNPC E2F4 KAT5 SIVA1 HIPK2 LRIG1 ERCC1 KAT2B NFE2L2 SP1 CDKN2A E2F3 BMI1 CYP3A5 TIGAR TNFRSF10B BCL2L11 MAPK9 SPHK2 APAF1 PPM1D ABCB5 ABCA2 LRPPRC HUWE1 ZBTB17 CIAPIN1 ABCB1B ABCB1A SENP8 NFYA MYB DMTF1 MGMT CCNG1 NEIL2 PPM1G BIRC7 TRP63 GLS2 RBM38 BABAM2 CCNH FZR1 AF366264 PIN1 PPP1R1B TRP73 POU4F1 TCEAL1 Daunorubicin Top 200 Predicted Genes from Geneshot AutoRIF via AutoRIF Co-Occurrence Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). CD79B IMPDH2 BIRC3 ABCC1 PPP2R1A CCND3 FCER2 RUNX1 ESR1 HSP90AA1 TLE3 SLC28A1 ATM TP53 BIRC2 ABCG2 CD7 NPM1 TOP2B BCL2A1 MCL1 CHEK2 BCL2 BCL2L2 MECOM TNFSF10 RARB PTGFR GADD45A KRT19 TFF1 CCND1 SLCO2B1 CYBA RARA ABCC3 TOP2A CEBPA FLT3 CDC25A BIRC5 TP53I3 SLCO4A1 CCNB1 CBR1 DPYD MKI67 SLC22A16 TYMS ABCB1 MLF1 AKR1C3 MYH11 ABCC9 ABCF3 ABCC5 ABCC4 ABCF1 ABCF2 ABCC6 ABCD4 ABCC2 PIK3CA ABCE1 ABCG1 CYCS CCNE1 SULT2B1 RARG CDH3 ZNF217 ABCA7 IRF4 CASP2 RAD54L CD5 MELK RAC2 CD3E CD96 CD2 XAF1 CCNE2 CD19 CASP4 INHBA EPHX1 AKR1A1 GSTP1 HPGD NCF4 BIRC8 SLC38A4 CCND2 BCORL1 BBC3 NQO1 RRM1 SLC29A1 BCOR HSD17B2 DIABLO PPP3CA ABCB10 AKR1B1 STAG2 ZMAT3 AKR1B10 ETV6 SLC22A1 IKZF3 TFRC CD38 BCL2L10 CASP7 TOP1 SLC47A1 SLC28A3 RALBP1 SOD2 CBR3 CFLAR MS4A1 UGT2B15 TNFRSF10D TUBB3 TNFRSF8 TP73 SKP2 PRKCD CASP9 PAX5 BAK1 FADD ABCB11 KCNJ15 CD33 GSTA4 NT5C2 ABCB6 MSI2 BCL6 CHFR STARD3 BAALC ERCC1 TNFRSF10A AKR1C4 ARID1A KLLN PROM1 ABCC10 RUNX1T1 BMI1 CYP3A5 ABCA8 DTYMK CCNG2 ABCA9 TNFRSF10B NQO2 ABCA3 SLC19A1 DAPK1 CAMK2G NRAS FBXW7 CD22 MAPK9 CD79A ABCB9 ERCC2 GSTM3 ABCB5 ABCA5 ABCA2 SLCO3A1 SLC22A7 CYP2U1 ABCB4 ABCB8 ABCA10 ABCC12 ABCC11 ABCB7 SLC5A6 GCLM AKR1C2 PHF6 AKR1C1 CCNG1 CDKN2D AKR7A2 STAT5B RPS4X MAP3K9 TOP3B CDK12 MMP15 PCDHGA2 Daunorubicin Top 200 Predicted Genes from Geneshot AutoRIF via GeneRIF Co-Occurrence Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). CASP6 CES2 BCL2L1 BIRC3 MAPK3 RB1 MVP ABCC1 STAT3 CYP3A4 PTEN MME RIPK1 EP300 ELAVL1 RUNX1 JAK2 XIAP HSP90AA1 ERG NFKB1 MAPK14 ATM TP53 BIRC2 FASLG RELA CSNK2A2 ABCG2 ERBB2 NPM1 NOS3 SMARCA4 SRC EGFR CSNK2A1 CASP3 CDK2 STAT6 TOP2B MAPK1 MCL1 CHEK2 BCL2 KRT5 TNFSF10 RARB TPT1 TP63 CCND1 MDM2 CD24 BAX SLCO2B1 NUMA1 AKT1 CYBA RARA ABCC3 PLK1 TOP2A EZH2 CEBPA FLT3 CDC25A CDK1 CDC6 E2F1 BIRC5 CCNB1 CBR1 MKI67 TYMS ABCB1 AKR1C3 CDKN1A ATR MYC ABCC5 ABCC4 BAD ABCC2 PIK3CA STAT5A CYCS CCNE1 MAPK8 FOXM1 AR MTOR IRF4 CASP2 CDC25C BARD1 CHEK1 XAF1 CD19 PML PIM1 PTGES3 YBX1 IRF1 GSTP1 JUNB JUN ALDH1A1 PDCD4 IL3RA ZBTB16 ERRFI1 BBC3 FOXO3 NQO1 ATIC PCNA APEX1 DIABLO AKR1B1 MALT1 GZMM RASA1 WT1 ETV6 BID POU2AF1 CASP7 TOP1 IGF1R YY1 PMAIP1 RALBP1 CBR3 FAS CFLAR PTPN6 CASP8 CDKN1B CARD11 TP73 PRKCD OGG1 MYCN TRADD CASP9 KIT PARP1 EGF PAX5 BAK1 PRKCA FADD TRP53 TRAF2 COPS6 BECN1 CD99 HSD17B1 RASSF1 HNRNPD PLK3 NCOR2 PIM2 NBN HNRNPC LRIG1 ERCC1 XRCC6 TNFRSF10A NFE2L2 SP1 CDKN2A RAG2 PROM1 KRAS BMI1 CYP3A5 TNFRSF10B BCL2L11 DAPK1 CD22 APAF1 FASL ABCB5 PTBP1 ZBTB17 ABCB1B ABCB1A AKR1C1 MGMT MET PPM1G BIRC7 RBM38 CCNH TCEAL1 STAT5B TOPBP1 CASP10 ENDOG Daunorubicin Top 200 Predicted Genes from Geneshot AutoRIF via Enrichr Co-Occurrence Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). UBE2D2 PIGS SPOP NUP54 SNX1 SAAL1 SHQ1 ACAD9 FAF1 AATF ZCRB1 GTF2F2 GRIN1 SRP54 HIGD1AP11 RAB8A ALG5 AGPS ADAM17 ALG8 SRP72 PHB PTH UBE2I RIOK2 PMS1 ZNF410 PIGK URM1 RMI1 VPS25 AR HDAC3 GOLPH3 PREB TPP2 SYF2 PRPSAP1 SUPT5H ANAPC5 UPF3A GEMIN2 SARNP PSMD13 UBE2N TTC1 SDHAF2 ACTL6A UCHL5 ACTR10 SNX4 NUP107 UBA3 TSEN34 RNF20 AASDH ANAPC7 ZMPSTE24 ACBD6 SUPV3L1 XRCC1 ORC4 APPL1 ZBED1 TYW1 TGS1 RALBP1 RAD52 AIMP1 POLR2C TRG POT1 NUBP1 PEF1 VPS45 ALG1 VTA1 HIKESHI UFD1 GLRX3 PSMD7 SRP68 PSMD9 SAMM50 AASDHPPT THUMPD1 TADA3 EXOSC10 TADA2A POLR2H FTSJ1 SCFD1 YEATS4 RNF113A EXOC1 SEC13 OLA1 OGG1 SUGT1 NXT1 PLAA ACTR1A GATB ANAPC10 VPS36 QRSL1 PPA2 RTCA GTF2H5 TIPRL TRNT1 COX11 TSG101 OGFOD1 SACM1L GLE1 HBS1L EXOSC7 TSNAX FAF2 API5 STXBP3 TSN HMOX2 STARD3NL PRPF6 GPN3 COQ2 PLRG1 TTC4 USP39 ALG3 GID8 TP53RK PWP1 SCO1 GON7 GORASP2 PIK3C3 USP4 APIP SLC30A5 SEC23IP SMIM12 STK25 PHKG2 AKAP10 CPSF3 XPC UTP6 HSF1 UBR2 UBR1 RABGAP1 AAAS TAF2 PTPRA EXOC4 RBM4 GOLGA5 ST13P19 SART3 PRPF38A ANAPC1 UTP3 SKIV2L2 CPSF2 ORC5 NUP50 SUDS3 ZNF639 ANKRD27 THOC3 RPP30 ORC3 TDP1 NUP205 ANAPC4 PMS2 USE1 VPS8 SEC63 SNRPC ZNF24 UBP1 THOC5 ZNF282 WDR70 VDAC1P1 RFWD2 VIRMA ZNF746 SRIP2 PRPSAP2 SUPT3H GNPAT EXT3 FBXW2 NUP133 SDHAF3 Daunorubicin Top 200 Predicted Genes from Geneshot AutoRIF via Tagger Co-Occurrence Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). CD79B IMPDH2 BCL2L1 BIRC3 MVP ABCC1 ANPEP DDX10 MME SLC22A9 RUNX1 XIAP MTMR11 BIRC2 FASLG ABCG2 NUP214 CD7 TDP2 NPM1 AKR7A3 TOP2B RABEPK CRADD MCL1 CHEK2 BCL2 BCL2L2 TNFSF10 RARB GADD45A GSTA1 CCND1 SLCO2B1 SPN PRAM1 ABCC3 TOP2A DHRS4 CCNA2 CAPG NAIP FLT3 CDC25A BIRC5 TP53I3 CCNB1 CBR1 SLC22A16 TYMS ABCB1 MLF1 AKR1C3 ABCC9 ABCF3 ABCC5 ABCC4 ABCF1 ABCF2 ABCC6 ABCD4 ABCC2 ABCE1 ABCG1 HPGDS RARG ZNF217 ABCA7 DCK IRF4 CASP2 CDC25C RAD54L TAP1 CD5 H2AFX CD2 RAD51AP1 XAF1 CCNE2 CD19 CASP4 AKR1A1 SH3BGRL ALDH1A1 GSTA3 IL3RA ZBTB16 CD164 BIRC8 SLC22A6 GSTA2 CCND2 BCORL1 BBC3 SLC22A11 ILF2 RPA2 HSD17B2 DIABLO ABCB10 AKR1B1 TAP2 BID SLC22A1 CD38 TTF2 CCDC28A CASP7 TOP1 SLC47A1 PMAIP1 SLC28A3 RALBP1 CBR3 FUT4 CFLAR CASP8 UGT2B15 TNFRSF10D TUBB3 TNFRSF8 TP73 SKP2 TRADD CASP9 KIT PARP1 MLLT3 PAX5 FADD ABCB11 CD33 GSTA4 ABCB6 BCL6 CHFR C19ORF48 STARD3 BAALC ERCC1 CEP72 AKR1C4 SLC22A8 SLC22A13 PROM1 ABCC10 BMI1 CYP3A5 ABCA8 NSD1 CCNG2 IL6ST ABCA9 TNFRSF10B ABCA3 MRPS7 CD22 APAF1 CD79A ABCB9 BCL2L2-PABPN1 ERCC2 GSTM3 ABCB5 ABCA5 ABCA2 PARP4 SLCO3A1 SLC22A7 CYP2U1 ABCB4 ABCB8 ABCA10 ABCC12 ABCC11 AKR1C2 ABCA6 PHF6 AKR1C1 RBM17 CCNG1 PSMA5 CDKN2D LINC01060 TP53TG1 AKR7A2 TOPBP1 TOP3B CASP10 CAVIN2 NOP53 KIAA1210 DNTT DHDH LTK HSPB7 MAP3K21 MTRNR2L4 TCL1A Daunorubicin Top 200 Predicted Genes from Geneshot AutoRIF via ARCHS4 Co-Expression Gene Similarity Daunorubicin (also called daunomycin) is a chemotherapy medication with potential use for COVID-19 (e.g. Farag et al. (2020) Identification of FDA Approved Drugs Targeting COVID-19 Virus by Structure-Based Drug Repositioning, ChemRxiv). XPO6 GMIP NMI ARRB2 LYN HLA-B ZBTB7B NLRP6 CFP HLA-C TRIM25 HLA-A FMNL1 SIRPB2 IL17RA ICAM3 SPI1 STAT6 MYD88 STXBP2 LCP1 TMEM71 ARHGAP30 ITGB2 LSP1 MYO1G ARHGAP4 IL4R PARP10 ATG16L2 C15ORF39 TMC8 PARVG VASP RPS6KA1 PLCB2 LRRC25 CD37 GRK2 CYBA SHKBP1 ITGAL UNC13D PSD4 ADGRE5 TYK2 TBC1D10C ARAP1 HLA-E EPSTI1 TNFRSF10C CXCR2 STAT5A FRAT1 INPP5D FRAT2 ELF4 NBEAL2 AP5B1 TNFRSF1A ARHGAP27 RAB43 HCLS1 SASH3 PSTPIP1 DENND1C NLRC5 LCP2 TAP1 RASAL3 DEF6 CCDC88B SECTM1 RAC2 CORO1A FAM78A PTPRC VAV1 MYO1F CTSS OAS2 PTAFR TCIRG1 ADAR GBP2 PARP12 HSH2D CASP4 NOD2 UBA7 SP110 IRF2 IRF1 RHOG SIPA1 LITAF GIMAP4 LIMD2 LAPTM5 HCK THEMIS2 NCF4 EFHD2 RASSF5 FPR2 ZDHHC18 RGS14 IL16 TAGAP TLR6 IKZF1 CYTH4 ARHGAP25 TNFRSF14 FLOT2 PPP1R18 MXD1 RIPK3 TAP2 P2RY13 CSK CASP1 TRIM21 GSDMD SELL TRIM14 NCKAP1L WAS SNX20 ACAP1 FPR1 MNDA LGALS9 TRANK1 VNN2 FAM65B RNF149 CNPY3 GPSM3 PTPN6 R3HDM4 RNASET2 CSF2RB CD53 EVI2B KIAA0040 DPEP2 ADAM8 NCF1 APBB1IP TLR8 IL10RB IFNAR2 FUT7 NCF1C APOBR SIGLEC5 C17ORF62 LILRB3 CD300A SH3BP1 RIN3 ARHGAP9 NADK NCF2 C19ORF38 RGS19 PIK3CD ARHGAP45 DOK3 FGD3 CPPED1 ELL MOB3A STK10 CYTH1 CDC42SE1 WIPF1 PROK2 CEACAM3 SMAP2 IL6R NFAM1 ADGRE3 LILRA2 CXCR1 S1PR4 C10ORF54 STAT5B GRK6 DOCK2 AKNA ARHGEF1 RCSD1 STARD5 JAML SH2D3C DOCK8 NRROS HCG27 Ebselen Top 200 Predicted Genes from Geneshot GeneRIF via GeneRIF Co-Occurrence Gene Similarity Ebselen is a synthetic organoselenium drug with anti-inflammatory, anti-oxidant & cytoprotective activity. It is a top COVID-19 drug repurposing candidate (Jin et al. (2020) Structure of Mpro from COVID-19 Virus and Discovery of Its Inhibitors. Nature). IL2 IL1B IL6 MAPK3 PRKCZ CCL2 CCL5 NOX4 VCAM1 STAT3 EGR1 TNF HRAS IL1A RHOA TLR4 HSPB1 IFNG SMAD3 IL12B NCK1 NFKB1 HMOX1 IL4 MAPK14 GPX1 SERPINE1 ADAM17 RELA SRP72 FYN NOS3 TRIM31 TGFB1 SRC CAT PPIA CASP3 IL10 PTK2 MAPK1 GRB2 RPS6KB1 KDR ACO1 RPS6KA5 IKBKB BCL2 CP CXCL1 CXCL6 PIGR DUOX2 GADD45A MAPK10 IL4R SHC1 AKT1 CYBA LRP1 TIMP1 GLRX ADAM15 PRDX1 PRDX3 PSMB7 CXCL8 PTGS2 CDKN1A BAD COL1A1 MMP1 ELANE FOXO1 MAPK8 MTOR MMP3 MMP8 F2R MAPK11 HIF1A MAP2K6 CEBPB TNFRSF1A MAPK13 LAT CCL20 CYP2E1 ALOX15 SELE CYBB IL1RN MMP12 IL5 F3 PLAU CSF3 FOS RAC1 DUSP1 TXNIP TXN ICAM1 GSTP1 JUN VEGFA PRDX5 SOD1 GPX4 LTA NOS2 MUC5AC GPX3 IRS2 FOXO3 NQO1 MIF TIMP2 APEX1 GLRX2 SIRT1 MMP9 IL1R1 TLR2 CASP1 MMP13 PDK4 MAP3K8 MAP2K1 PIK3CG OLR1 NOX3 IL32 PIK3R1 CHUK SOD2 PTGS1 PRTN3 MPO ROCK1 CD44 SESN2 MMP2 NCF1 FGF2 PRDX2 PRKCD TRAF6 NXT1 NCF2 CREB1 TNFSF11 SYK MMP14 ARRB1 EGF PRKAB1 TXN2 PRKCA MAPKAPK2 TRP53 LTB4R CARD8 PTP4A1 PLA2G4A NOX1 RAF1 SPHK1 AGTR1A NFE2L2 SOD3 PRKCE MMP7 SP1 SIRT6 ELK1 PTPN11 TXNRD1 MAP3K5 GSR MAPK7 PRKAA1 PAK1 MAPK9 CXCR1 SIRT2 PLD1 PLA2G2A ALOX12 ATF2 TIAM1 MAP2K4 PRDX6 TXNRD2 MAP2K2 ATF1 TXN1 SHC3 CXCL15 CCDC134 Ebselen Top 200 Predicted Genes from Geneshot GeneRIF via Enrichr Co-Occurrence Gene Similarity Ebselen is a synthetic organoselenium drug with anti-inflammatory, anti-oxidant & cytoprotective activity. It is a top COVID-19 drug repurposing candidate (Jin et al. (2020) Structure of Mpro from COVID-19 Virus and Discovery of Its Inhibitors. Nature). FCGRT FKBP1A PSMD8 RNPEP TMBIM1 FURIN ADAM9 GNG5 GRPEL1 RAB8A ACAA1 SELENOS NUCB1 ADAM17 ACADVL SDF2 RARS AGTRAP ARF6 PLP2 RAB5C TMBIM4 TM2D2 VAMP8 PTTG1IP TBCB VKORC1 ACOT13 TPST1 PLA2G15 STT3A TMBIM6 RMDN3 PGD VASP H6PD GRINA CORO1B PLOD1 PLEKHO2 TMED9 GRN SYNGR2 GALNS SCAMP2 TWF2 SQOR SCARB2 CREG1 HSD17B4 SCPEP1 SEC11A ADPRH ANXA5 RAB13 HADHB RRAS SNAPIN GSTO1 HEBP1 HEXB ALDH9A1 PRDX3 PRELID1 HINT2 TNFRSF1A TCIRG1 PSENEN PSME2 SHISA5 AKR1A1 ADIPOR1 RHOG GNG10 PPIB GABARAP PLSCR3 RAP1B TAPBP SH3BGRL3 TM9SF2 FDX1 FUCA1 TALDO1 SLC39A1 HEXA PSMA6 SERPINB6 GYG1 GNS GM2A TVP23B VPS26A SAR1B OAT RAB9A RAB5A TMED2 TMEM147 UBE2A PRR13 ALAS1 TXNDC17 TMEM205 ZNHIT1 FLOT2 SAR1A YIPF3 FAM96A ETHE1 SSR2 AP3S1 TMEM50A TAX1BP3 TSEN34 GNA13 HSD17B11 SRI PGM1 CSK SPPL2A WSB2 GINM1 RALB SOD2 RNF149 ALDH2 SERPINB1 SERP1 ACTR3 IFNGR1 PEF1 SEC13 SURF4 SLC31A1 TSG101 RIOK3 IFNGR2 TXNDC5 ESD ERP29 PLEKHB2 GBA UBAP1 SELENOF HMOX2 SPG21 PITPNA ANXA7 SNX6 FKBP2 POLD4 TMEM165 HAGH TNFAIP1 GSTK1 RNF181 SUCLG1 STX12 TMEM9B TMEM43 UBE2F ARF4 ANXA4 TSTA3 SMPD1 SMAP2 FLOT1 SLC39A7 ACP2 PPP2CB SLC31A2 ACOT9 PLIN3 WDR1 PRCP GSR RAB32 GCLM TRBV13 GUSB AKR7A2 SCGB1D1 TMEM59 RPS2P36 CRTAP PLOD3 HMGCL TMED3 RNASEK HSD3B7 RHOC SLC35B1 RILPL2 UGDH TMEM14C RPL31P17 SDCBP SUSD6 ERO1A Ebselen Top 200 Predicted Genes from Geneshot GeneRIF via Tagger Co-Occurrence Gene Similarity Ebselen is a synthetic organoselenium drug with anti-inflammatory, anti-oxidant & cytoprotective activity. It is a top COVID-19 drug repurposing candidate (Jin et al. (2020) Structure of Mpro from COVID-19 Virus and Discovery of Its Inhibitors. Nature). NKX3-1 ADAMTS1 IL1B MAPK3 SH3BGR PBLD COL6A1 NOX4 YWHAG ANXA3 ECSIT NCK1 NFKB1 HMOX1 MAPK14 GPX1 HEPH SELENOS PSMC6 CXCL2 CAT MAP3K1 PTGES2 MAPK1 GRB2 ACO1 IKBKB PFDN5 HIST1H2BC GPX2 DUOX2 PTGFR CYBRD1 FTL TAGLN2 PDIA6 RPS6KA1 AKT1 PTK2B CYBA SELENON PDIA4 TIMP1 GLRX ADAM15 MT1F TIMP4 PRDX1 ATP5F1B PRDX3 CGREF1 MMP1 FOXO1 MAPK8 MMP3 MAP2K3 MAPK11 MAP2K6 TRIM49 DUSP2 ARHGDIB ADAMTS4 CYBB CDH16 DIO2 ANGPTL2 EPAS1 IER3 RAC1 DUSP1 GSTM5 TXN GSTP1 HPGD PCBP1 MORF4L2 JUN P4HB ADAMTS15 PRDX5 GSTA3 RHOQ SOD1 NCF4 GLRX5 GPX4 TGFB1I1 SRPX GPX3 FOXO3 MMP10 NQO1 TXNDC17 POLD2 PGAM1 CFL2 PRDX4 TIMP2 GLRX2 SIRT1 DUSP10 ID1 FOXO4 SRXN1 DOK4 MMP9 MMP13 MAP2K1 NOXA1 NOX3 TMEFF2 CHUK SOD2 MSRB1 ADAM10 ADAMTS5 ACTA2 NCF1 PRDX2 GLRX3 ADGRE1 NCF2 TRIM63 TIMP3 MMP14 MAP3K7 TXNDC5 SELENOF TXN2 MAPKAPK2 GSTK1 TPM1 GSTA4 GAB2 PDIA3 P4HA1 PLA2G4A NOXO1 NOX1 SELENOK NFE2L2 SOD3 MMP7 GCLC KEAP1 DUOX1 ELK1 GPX5 TXNRD1 P4HA2 MAP3K5 GSR MAPK7 MAPK9 FBXO25 GSTM3 GCLM GSTT2B TRAF4 MAPK12 CCNG1 TFDP1 PSMA5 MAP2K4 MMP15 GPX6 MAPK4 NLRP9 ACOX3 PRDX6 TXNRD2 TXNRD3 NLRP5 COL16A1 DIO3 PI4K2A SELENOT SELENOP MSRA SLC48A1 MMP17 SELENOH MAP2K7 GPX8 SELENOW NOX5 SELENOV IREB2 DUSP12 LOXL3 ZAR1 SELENOM KIF9 SELENOO ZNF142 TUSC2 SELENOI GPX7 TXNDC9 MT1G Ebselen Top 200 Predicted Genes from Geneshot GeneRIF via ARCHS4 Co-Expression Gene Similarity Ebselen is a synthetic organoselenium drug with anti-inflammatory, anti-oxidant & cytoprotective activity. It is a top COVID-19 drug repurposing candidate (Jin et al. (2020) Structure of Mpro from COVID-19 Virus and Discovery of Its Inhibitors. Nature). SLC36A1 IL1B FCGRT ATP13A3 CD14 MVP CTSL TSPO LILRB2 IL1A SLC7A7 TLR4 CXCL16 TMBIM1 LYN KCNQ1 SIRPA NUCB1 TRIM25 ARHGEF11 FKBP15 SRC MYD88 RAB5C BRI3 TLN1 ATP6V1B2 MGAT1 BCL2A1 NINJ1 IGSF6 SERPINB2 CD300E FTL MAN2B1 TNFAIP2 TMEM127 ITGAX HS1BP3 VASP GRINA TBC1D2B GAA EMILIN2 LRP10 PLEKHO2 SLC15A3 ITGAM ARAP1 ITGA5 GRN HCAR2 HK3 ZYX C3AR1 PLBD1 CREG1 RAB20 LHFPL2 ANXA5 CTSZ MMP19 TBC1D2 CLEC12A CXCL8 PTGS2 SLC2A6 B4GALT5 CD300C PLAUR OSM LAMP1 MAP2K3 ELF4 TFE3 BCL3 FOSL2 CEBPB AP5B1 TNFRSF1A MS4A7 GPR84 CLEC5A PIK3R5 CLEC4A CCR5 GLIPR1 CTSS FCER1G CXCL3 CCR1 IL1RN OSCAR CLEC4E PTAFR CLEC4D SOCS3 TREM1 NFKBIE GLIPR2 NOD2 C5AR1 GNAI2 IER3 DRAM1 LITAF TYROBP IFI30 TALDO1 PSAP EHD1 GNS HCK THEMIS2 PICALM ZC3H12A SIGLEC7 PPP1R15A SIGLEC9 PFKFB3 S100A11 ATP6V0D1 PPP1R18 SRXN1 C15ORF48 DENND5A ITPRIP TLR2 CASP1 CCRL2 IRAK2 SLC43A2 METRNL RNF19B TPRA1 CHST15 TICAM1 N4BP1 SOD2 MOB3C SRGN PLEK CDC42EP2 SERPINB8 ADORA2A CD68 FCAR TLR8 PRKCD PILRA ADGRE1 TBXAS1 SIGLEC5 LILRB3 TNIP1 FGR STX11 NCF2 C19ORF38 GK SIGLEC14 AQP9 HLX IFNGR2 STX4 TOM1 ACOD1 ELL LACTB NR1H2 SQRDL IRAK3 TREML4 ACSL1 HCAR3 PSEN1 MYO9B PLEKHM2 FAM214B MFSD7 SLC31A2 PTPRJ NPL AMPD3 AC018755.18 NLRC4 IL6R IGF2R CD300LB NUMB IL13RA1 DSE OGFRL1 SPSB1 CSGALNACT2 LIPN TPD52L2 DNASE1L1 ANTXR2 RP11-12A2.1 Genes whose expression is altered by MHV infection See the following paper. Novel Method for Detection of Genes With Altered Expression Caused by Coronavirus Infection and Screening of Candidate Drugs for SARS-CoV-2 dx.doi.org/10.20944/preprints202004.0431.v1 UBB RPS27A EEF1A1 RPL12 RPL36 UBC RPL13 IFITM3 AHSG FABP1 GPX1 B2M FAU PABPC1 HSPA8 ALB RPS17 RPL37A MT-ND3 RPLP2 RPS11 MT-ND1 RPL41 RPS24 TPT1 RPL6 RPS8 MT-ND2 MT-CO3 RPSA RPS15 HIST1H4H MT-ATP6 RPS18 RPL19 LCN2 MT-ND4 RPL7A RPLP1 RPL11 RPS7 RPL7 BST2 HP RPS2 ACTB TMSB4X HPX CFB S100A9 AMBP FGG FTH1 RPL8 ACTG1 EEF2 RPS23 RPL3 RPLP0 RPL5 RPL26 RPS5 RPS21 CD74 RPS9 PSAP EEF1G FGB GC PTMA RPL32 HIST1H3B APOA2 S100A8 RPL23A RPS6 RPL17 RPL36A APOE LARS2 APOC1 FGA RACK1 SERPINA1A MT-ATP8 APOA1 ORM2 MT2 RPS4X HBB-BS H2-T23 HIST2H2AA2 LYZ2 HSP90AB1HSP90B1 SERPINA3K MT-CYTB C3CCNB1IP1 IFI27L2A HAMPHBA-A2 RPS27RT RPL38RPL4 FTL1GAPDH WFDC21 GM2000 SERPINA1B MYH9ORM1 H2-D1 RPL10-PS3 SAA1SAA2 MT1 H2-AA MT-CO1MT-CO2 RPS12RPS14 HBB-BT H2-K1 RPL13ARPL14 SERPINA1D SERPINA1C RPS3A1 GM10800 TRFTTR RPS29RPS3 Genes whose expression is altered by SARS=COV-2 infection See the following paper. A New Advanced In Silico Drug Discovery Method for Novel Coronavirus (SARS-CoV-2) with Tensor Decomposition-Based Unsupervised Feature Extraction dx.doi.org/10.20944/preprints202004.0524.v1 RPS27A EEF1A1 HSP90AB1 SQSTM1 RPL12 YWHAZ ACE2 PKM ANXA2 TUBB4B PMEPA1 HSP90AA1 SERPINE1 ATP1B1 STAT1 ERBB2 PABPC1 PPIA STC2 SPTBN1 NAP1L1 RPS20 ENO1 KRT5 KRT18 ITGA2 RPL9 GPX2 RPS3A RPL23 KRT19 S100A2 LCN2 RPL7A RPL7 FTL CD24 TNFAIP2 ABCC3 DHCR24 TOP2A DDIT4 GAPDH LDHA TPI1 MTHFD2 IGFBP3 TRAM1 ACTB HMGA1 LAMB3 EREG TMSB4X PSAT1 OAS2 IFIT2 NAMPT SLC7A11 SERPINA3 RNF213 FTH1 RPL28 PFN1 YBX1 IER3 TUBA1B IGFBP4 ACTG1 EEF2 TXNIP JUN CTGF VEGFA RPL5 RPS19 P4HB RPL10 RPL26 ALDH1A1 RPL4 EIF5A PSMD3 S100A6 TUBB VIM ATF4 CALR CFL1 FASN SLC38A2 PPP1R15A LIF TIPARP NQO1 NEAT1 AKR1B10 ASNS ACTN4 ALDH3A1 HNRNPA2B1 CRIM1 LAMC2 MYL6 RPS6 FADS2 KRT6A PGK1 AHNAK CPLX2 G6PD STARD3 ITGA3 AKR1C2 RPS4X ANTXR1 NFKBIANPM1 KRT81 ITGAVITGB1 TXNRD1UBC TPM1TPT1 KRT23 ALDOAAMIGO2 FDCSPFDPS GSTP1H1F0 FLNB AKAP12AKR1B1 SLC7A5SPP1 CXCL5CYP24A1 RPS24RPS27 SAT1SCD RPL3RPL37 GAS5 ASPH DCBLD2 KRT7KRT8 PTMARAI14 LOXL2MIEN1 C3CALM2 PLAUPLOD2 HSPA8ICAM1 TGFBITGM2 EIF1EIF4B 500 genes down regulated by MERS infection of Calu3 cells MERS is similar so SARS-COV-2 and induces similar effects EIF4H TBCA SUMO2 CTSL YWHAQ NPTN NMI SLC1A1 NPC2 RHOA MYO1D PDZD11 TPM4 ATP6AP2 TMEM97 ZCRB1 KHK GABARAPL2 NDRG1 CENPF HSP90AA1 RAB8A FAM162A H3F3A CALM1 BZW2 TUBA1C HLA-C ERP44 ATP1B1 HLA-A SAP18 B2M TSPAN8 MFGE8 BRCA1 STOM NUP85 PRKAR2A APP UBFD1 PAICS PLP2 MDH1 GLO1 HIBCH ADH5 BPNT1 PTTG1IP NDUFB6 DDT ADK PSMA2 CAV1 BTF3 LCP1 VKORC1 PARVA DDAH1 ERBB3 RPL14 RPS24 UPK1B S100P GPX2 S100A14 PBX1 OSMR GALNT3 RPL30 BCAS1 CKS2 RPL39 GPRC5A TACSTD2 COX7C KIAA1143 LCN2 RPL7A CHST9 RPL31 GABRP CD24 TSPAN3 TMBIM6 STMN1 GRN NDUFB5 GAS2L3 CCNA2 CAPG LMNB1 CCNB2 XXYLT1 GTSE1 CDKN3 UBE2C CREG1 HSD17B4 HADHA GLRX NEK2 MGST1 SEC11A HMMR MTCH2 ARPIN FH AURKA DLGAP5 BUB1 RRM2 PRDX1 PRR11 TPX2 HEXB CEP55 IDH1 CDCA3 KIF23 ALDH9A1 DYNLL1 CENPU MICU1 PRDX3 LIPA SORT1 KIF20A ENPP5 TPM2 IGFBP3 CDS2 HINT1 ZNF185 MAVS APLP2 TRAK1 CDH1 B4GALT4 FGFBP1 SCNN1A WLS CLU ODAM CD63 PDLIM5 UBE2T CENPA ASF1B CHEK1 SPC24 HELLS OIP5 RACGAP1 SPC25 HMGB2 KIAA0101 DHFR CLDN2 GBP2 SERPINA3 CD59 FTH1 DPYSL2 PTGES3 LASP1 TUBA1B HMGN1 MYL12B TGM2 ELOVL5 PEBP1 ATP6V0E1 GSTP1 MRFAP1 ITM2B PSMB9 GBP3 CHCHD2 SH3BGRL FABP5 NPNT RBBP7 UQCRC2 H2AFZ C14ORF166 LYZ GDI2 ACAT2 COX8A ARPC3 NME2 LAPTM4A S100A6 SH3BGRL3 PAIP2 CCT4 CETN2 NDUFB11 BRK1 PDCD4 CD74 SRP14 DYNLT3 NDFIP1 RPL15 IFI30 SOD1 KLHDC3 COX6B1 RBBP4 DNAJA1 PSMA6 DSTN SERPINB6 GNS LXN GM2A NDUFV2 VBP1 GLRX5 CHCHD1 DBI RPS27L VCL OAT S100A10 ATP5J2 SERINC3 PGRMC1 CD9 CBX3 TMEM14B LIMD1 CALB2 ANP32A ZNHIT3 ZBTB8OS NQO1 VAMP3 RNASEH2A SRP9 DYNLT1 ORMDL2 GMPR2 TMEM230 CORO1C TIMP2 LMAN1 PAM PCBD1 GJA1 AHSA1 CAP1 TNFRSF21 APEX1 FAM107B NIT2 LACTB2 SEPT10 SPCS1 UQCRH TMEM50A TMSB10 HSPE1 DECR1 MRPL11 LRP11 LDHB HSD17B11 SERINC5 ACBD5 SKA2 MRPS6 APOBEC3C SRSF2 AKR1B10 SRI VEGFB ID2 KLHL24 ATP5E NIPSNAP3A MVD ATP5G2 GMDS NUP43 GSDMD PDK4 ELOVL6 HLA-DMB PTGR2 RECQL PRTFDC1 WDHD1 IDH2 LRRC45 TFPI2 PCYOX1 LIPH GALNT11 SEMA3G ACOT7 EMP1 SCAMP1 UGT1A6 FAM210B ANP32B ERICH5 GLUD1 CSTB ERAP2 FMR1 PYGL RSU1 CTSA CLIC1 NDUFB4 COX5B SNRPB2 NONO CD44 GNE LAMA3 ITGB6 PLSCR1 RARRES1 PGK1 SNRPD3 DARS STX7 ESD PLEKHB2 PHGDH GDE1 GSTK1 CALCOCO2 SPP1 SYAP1 NNT TPM1 SCD5 VSIG1 ATP1B3 CAPZA1 ACAT1 CD99 ACAA2 ANXA4 MANSC1 ORAI3 CLDN1 PNMA2 P4HA1 SMS THOC7 ASNA1 HOXB6 G6PD STK24 CYSTM1 RTN3 SUN1 FDPS XRCC6 PUDP CPNE3 WDR1 PRCP PPARA SLC5A3 MMP7 SEMA4G LEFTY1 PRSS12 SLC44A4 FXYD3 PROM1 SLC2A12 BACE2 CCNG2 GPM6B FIS1 FBXO25 GSTT1 GSTM3 WDR48 EXOC4 ICMT FLVCR1 ACSS2 FUBP1 RCN1 HP1BP3 NUDT15 HN1L HNRNPAB XRCC5 PRDX6 CRTAP TMEM14C COX7B AHCYL1 NYNRIN SMC1A CTDSPL BRCC3 TUBGCP4 CEBPZOS PALMD FAM213A UBASH3B BCAM DYNLRB1 ANXA9 C22ORF23 KIAA1161 TMEM19 TPGS2 VANGL1 BCKDHB HSP90AA6P HECA SLC35E2B DBNDD2 FAM81A TMEM87B PTRF IMP3 TIMMDC1 LEPROTL1 ADGRF1 RNASEH2C MFSD6 SLBP IKBIP NUDT21 EHD2 PDSS2 NAALADL2 CHRNA5 PCDHGA9 SLC39A6 TMEM248 TIAL1 RFT1 RMI2 PXYLP1 GINS4 METAP2 DARS2 SLC41A3 NEMP1 ANAPC16 KDELR2 ALDH7A1 FBXO2 F11R POLR2L CDKN2AIPNL MFSD14B FITM2 HACD3 KIAA1147 DUT ATP5F1P5 BCL7C SEL1L3 IARS2 HSD17B12 OAZ2 RTF1 SDHC CSN3 SSBP1 GPC4 MFSD1 ADGRG6 PFKFB4 TCAF1 CHCHD3 DENND6A BMP8B ACTG1P19 NIPSNAP1 MSL3 MAGED2 OCIAD1 EIF3H EIF3L PEG10 SLC4A7 ATP5B LINC01420 FAM127B MRPL30 RPL23AP42 GBAS TOMM7 PDDC1 500 genes up regulated by MERS infection of Calu3 cells MERS is similar so SARS-COV-2 and induces similar effects ADAMTS1 BIRC3 IL6 EGR1 LARP1 UBD STX3 KPNB1 PKP2 RRP9 GCC1 GOLGA3 NGDN ZNF274 KLF6 RNF41 EHBP1 BRD2 FRMD6 GIGYF2 MARK3 USP54 NPLOC4 NOS3 CXCL2 USP21 USP15 CCDC86 MAP3K1 GSK3B HKDC1 ATXN2 RHBDD3 ZC3H12C NR3C1 ZNF410 NCOA5 EIF4B CXCL1 TRPS1 DUSP16 GCNT3 HSPB8 TET2 GADD45A RND3 BDP1 TJP1 KIAA1671 PTPRZ1 EHF ZNF462 NEDD4L STT3A THBS1 SRPRA MBD1 GGA1 SMAD7 SLC38A7 ZBTB43 RBBP8 ELL2 MAFG CDC6 SPATS2L NRIP1 GNPDA1 CXCL8 ARL4C TOPORS EGR3 STAM TUFT1 KLF10 TGFBR2 GADD45B BDNF MED23 CSNK1G1 WWC1 TRIM16 FAM83G IRF6 SLC7A5 ZNF217 WDR7 SOX9 ATF3 ELP3 TFCP2 EFNB2 ELF4 BCL3 FOSL2 TAB3 NUAK2 BRPF3 ZNF710 CCL20 CXCL3 FSTL4 NAV3 IFIH1 VCAN NFKBIE TNFRSF12A INHBA FOSL1 CSF3 TSC22D1 ETS1 KLF4 CYR61 CYTH3 IER3 SNRK IRF1 DUSP1 TXNIP ICAM1 NFKBIA JUN VEGFA PISD ARRDC3 CRELD2 PIM3 DHX30 CCNL1 DNAJB1 FNDC3B EEF1G NRP1 ZFP91 YTHDC1 GEM ARRDC4 SLC8A2 KDM6B CREB5 ZC3H12A DDIT3 AKAP17A SLC25A25 TRAF1 PPP1R15A CSF1 KIAA1551 ZSCAN9 LONRF3 TNFAIP3 SOCS2 HDAC9 ZNF35 NTNG2 COL20A1 E2F6 FILIP1L CDKN2AIP BRD1 NEURL3 TIPARP CSRNP1 MAFF TSC22D2 SERTAD2 CDC42EP3 KANSL1 FOXO3 FOSB PPRC1 MSL2 PSME3 POLR3C AMD1 PITPNB ETF1 GEMIN5 NKRF ZNF317 INTS6 USP10 ADORA2B FXR2 PAN2 SAMD4A TNFSF15 GSPT2 SETD2 MAML1 SCAF8 HIVEP2 YTHDF2 DPH2 RND1 NECAP1 ZNF211 REL ABL2 TRA2B COX10 ZCCHC2 SMOX IKZF3 ADPRHL1 IRAK2 AARS FAM171A1 IL32 NHS BCL10 CHD4 TAF3 GLIS3 TULP4 ASH1L RUNDC1 RBM18 TP53BP2 MB21D2 RNF145 PPP1R10 HPS5 PLK2 RCAN1 CLUHP3 SEC31A NCEH1 PARP8 RASGRP1 RCOR3 CDON RAD52 PPTC7 SESN2 TRIB1 IL1RAP BCAR3 BACH2 TNFRSF10D FGF2 PTPN1 PLAGL2 RUBCN TRIM32 SUPT20H TNKS YARS XBP1 UBAP1 PRKAB1 FAF2 ZMYM4 SMURF1 AKIRIN1 UVRAG ZNF34 URGCP KIRREL PARP6 USP36 PHC3 MTA2 HELZ INPP5E RASSF1 RBBP6 ANKEF1 RIOK1 HMGXB3 VPS18 PDRG1 HNRNPC TANC1 PMM2 RRP12 EPC1 TSR1 FBXO31 RAF1 EDC3 LZTR1 TXNDC11 ANKRD17 POLR3A FAM83C RNF216 IL6R SYDE2 ZNF81 PER2 ZNF3 PARD3 ZBTB4 JMJD1C ARHGAP32 SHROOM3 BHLHA15 SETD5 CHD2 PITPNM2 TNFRSF10B ZFAT ATMIN DCAF1 FBXO32 MAPKAP1 UBR5 UBR1 RABGAP1 SLC30A1 RC3H1 GIN1 ZNF227 ZNF17 GOLGA1 ZNF398 ZNF197 RANBP10 GOSR1 CRAMP1 GOLGA5 RALGAPB RNF4 KAT7 MCPH1 ERN1 NFATC3 REPS1 BIRC6 MTF1 TTI2 PNO1 SART3 QTRT2 XPO5 PRDM4 DHX37 RRP1B LATS1 MAP3K9 CDK12 HSPA9 ARHGEF2 USP42 ARMC8 OSBP CELSR3 TNIK MAX KANSL3 PCNX2 KRT223P POGZ GTF3C4 EIF4ENIF1 KLHL18 ZKSCAN5 ASAH2B DIP2C NOP2 ATXN2L FAM179B FAM188B RP11-844P9.2 DDX20 ZC3H4 ZNF764 USP24 SCAF4 IGHMBP2 DPF2 TNPO3 NFRKB KCTD5 TBC1D22B YY1AP1 THAP1 TXNL4B SETDB1 FAM208B RBM33 FOXJ2 MED1 TANC2 ZC3H10 GMEB2 MTMR9 ATF7 NECTIN4 PIP5K1A NEURL4 LYST MED26 CSRNP2 C6ORF48 SIK3 SPATA2 ARID2 QKI ZNF335 SNX19 GGA3 CBLL1 SLC25A38 RNF146 MGA CNOT4 GCSAML SH3RF2 NOL6 SRPRB LETM2 GAPVD1 RAD51D ARHGAP17 ZBTB11 WTAP ZBTB9 ZNF280C ZBTB48 RP11-1070B7.2 ZNF16 IP6K1 GTPBP4 ZNF407 VWDE PSG4 TIAM2 ARID3B NAXD SEC24D C1ORF109 HMG20A GGNBP2 DOPEY1 RNF111 KRT8P12 DCP1A MTMR3 ZNF77 RHOBTB1 RUSC2 RASAL2 WAC ITSN2 ZBTB39 NFX1 DDX24 USP31 AC141586.5 EPS15L1 TNKS2 INO80 FGD6 C20ORF194 BRPF1 MLLT10 AEN ZBTB24 ORAOV1 BICD2 ZNF319 BICD1 MED13L ZNF526 KDM5C SFMBT1 LPIN2 NFXL1 ZNF550 CIDECP ZFX SPIRE1 LRIG2 KDM2A ZNF473 OR7E4P ABTB2 FNDC3A SMG7 FEM1A SRFBP1 TTPAL ZNF140 TMEM55B DNAJB6 GPATCH2L ANKRD40 MID1 TADA2B CEACAM19 ANKHD1 FAM168B MOK KIAA0753 MRM1 CHMP7 ELMSAN1 500 genes up regulated by SARS-COV-2 infection of Calu3 cells SARS-COV-2 infection of Calu3 cells NKX3-1 IL1B RSRC2 SEC16B BIRC3 IL6 CCL2 CCL5 VCAM1 EGR1 UBD TMPRSS3 NMI TNF PCK2 DDX58 IL1A CXCL10 MAST4 IFITM1 LYN NEDD9 LAP3 JAK2 KLF6 SMAD3 IFNL3 NFKB1 SERPINE1 OAS1 PTX3 INHBE STAT1 TRIM25 IFITM2 PTPRH EIF2AK2 PLAT APOBEC3G OASL CXCL2 IFNB1 ISG15 NUB1 CSF2 STC2 MX1 MYD88 WFDC5 ZC3H12C NR3C1 LIFR KMO ALDH1A3 MT2A CXCL1 TGFB2 TNFSF10 KRT17 HES1 DUSP16 ZEB2 PARD6B NR4A2 S100P DUOX2 NFAT5 C6ORF132 KIAA1217 PNRC1 RICTOR SERPINB2 GADD45A RND3 ANKRD33B PRDM1 SEMA3A ISG20 ZNF462 ARID5B TNFAIP2 PTGER4 PARP10 THBS1 HBEGF PTK2B TYMP BST2 B3GNT7 SLC15A3 SMAD7 ITGAM FBXO6 NLRP1 SDC4 ALDH1L2 ZBTB43 IFI44 EPSTI1 H1F0 SPRY2 APOL4 BATF2 MTHFD2 RASGEF1B G0S2 PTGS2 LAMA2 GATA3 AKAP12 NUAK1 B4GALT5 CDKN1A TUFT1 BMP2 ZFP36L1 KLF10 GADD45B EDN1 PLAUR FOXO1 BCL9L TFAP2A DSG3 IRF6 SLC7A5 ZNF217 EREG SOX9 NAV2 FGF19 ATF3 JAG1 TNFRSF11B BCL3 FOSL2 HELZ2 NUAK2 RSAD2 OAS3 CD69 IDO1 IRF7 ZBP1 NLRC5 GBP5 TAP1 CCL20 ULBP1 IFIT1 SECTM1 CYP1A1 PSAT1 IFIT3 RTP4 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 GBP4 DHX58 C1R KYNU USP18 CMPK2 IFIT2 IFI16 PTAFR NAV3 HERC6 IFIH1 STAT2 PML PLEKHA4 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L HSH2D PIM1 INHBA RNF213 IFI35 PARP14 FOSL1 TRAFD1 SAMHD1 F3 UBE2L6 TLR3 PLAU UBA7 FST WARS SP110 CSF3 SCN3A RIMKLB IRF2 ETS1 KLF4 ZFP36 CYR61 IER3 IRF1 RASGRP3 DUSP1 TXNIP ICAM1 DTX3L NFKBIA IRF9 PSMB9 GBP3 JUN CTGF VEGFA NR1D2 IFI44L SERPINB9 ARRDC3 ATF4 JDP2 ERRFI1 CCNL1 THEMIS2 PHLDB2 SAT1 GEM RBM11 ARRDC4 KDM6B CREB5 SAMSN1 ZC3H12A LST1 DUSP8 TRAF1 EGR2 NR4A3 EDN2 IFNL1 PPP1R15A CSF1 TRIM22 SERPINA10 B3GNT5 C6ORF58 TNFAIP3 HDAC9 CYTH4 ZNF267 PLA2G4C FILIP1L TP53INP2 GIMAP2 BBC3 AMOTL2 PPP1R15B NEURL3 LIF DUSP5 IRS2 TIPARP CSRNP1 MIR155HG CHAC1 BHLHE40 MAFF NFKBIZ TSC22D2 SERTAD2 ZNFX1 FOXO3 FOSB DEPDC7 PNPT1 AMIGO2 MXD1 DNAJB4 DUSP10 PDE4B ANKRD1 NEAT1 EFNA1 SAMD4A TNFSF15 MAP1B CREBRF ITPKC HIVEP2 C15ORF48 RND1 SERPINB7 SIK1 ABL2 ASNS SLFN5 CASP1 PPM1K IL15RA ZCCHC2 MMP13 TRIM21 TRIM56 ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 MAP3K8 RIPK2 IL15 DDO IKZF3 IRAK2 AJUBA SLC1A4 CYP1B1 CXCL11 GSDMB PER1 IFNL2 LAMP3 DDX60 RNF19B LGALS9 TNFSF13B XRN1 SP100 BCL10 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 ADRB2 SAMD9 GBP1 ST3GAL1 GARS TP53BP2 MB21D2 ETS2 CEACAM1 KLHDC7B HDX RELB RCAN1 ETV7 GMPR NFE2L3 PMAIP1 TICAM1 CX3CL1 SP140L C5ORF56 APOL3 N4BP1 RBMS2 BTN3A1 C1S SOD2 TRIM38 PARP8 IL12A PHACTR4 OPTN CFLAR GTPBP2 RAB8B SERPINB1 LTB RASGRP1 KRT6B DENND3 TRIB1 KIAA0040 BCAR3 BACH2 CLK1 SEMA7A BACH1 KRTAP2-3 CALD1 PLSCR1 NR1D1 HRASLS2 DUOXA2 NCOA7 C1QTNF1 CDC14A CCL22 BDKRB2 RIOK3 APOBEC3F TNIP1 NCF2 BCL2L14 SP8 CARS YARS NFATC2 IFNGR2 PELI1 NFKB2 NEDD4 OTUD1 CYLD KCNJ15 CITED2 BHLHE41 PDP1 ZBTB10 GPCPD1 PPP2R2A MARCH4 DAPP1 GBP1P1 MAP3K13 EPC1 NLRP3 LRP2 FUT3 DUOX1 RREB1 KDM6A DAB2IP CYP3A5 PDGFB PLEKHG7 CHD2 HMGN2P46 TNFRSF10B BCL2L11 FBXO32 CD22 NDUFA4L2 FUT1 FLT3LG CTH SAA4 SDS SYNPO UGCG SOX4 GATA6 LATS2 SPSB1 KRT23 FLNB TBC1D22B CSRNP2 TIAM2 DCP1A FGD6 SRFBP1 C18ORF25 PDZD2 ROCK1P1 DLC1 DEFB4A ZSWIM4 C6ORF223 SKIL C6ORF222 KBTBD2 ARHGEF28 L1CAM BAHCC1 FSTL3 TUBE1 EGOT APOBEC3D PA2G4P4 KIF21B GSE1 CXORF38 UHRF1BP1 TTC39B LRRN3 CLK4 CNKSR3 IFNL4 ADM2 SLC25A37 RAB11FIP1 ZNF385C NRCAM HIVEP1 SYTL3 500 genes down regulated by SARS-COV-2 infection of Calu3 cells SARS-COV-2 infection of Calu3 cells DCTPP1 TIMM8B UHRF1 MALL CISD3 KPNA2 SLC9A3R1 TINAG MME ANKS4B VIL1 CYB5B TMEM97 MIPEP PKM PRR15L TUBB4B CENPF SIGMAR1 AP2M1 TUBA1A CALM1 PMPCA ANXA13 ISYNA1 TSPAN8 PHB HSPA8 CAT THOP1 IGSF9 FBXO9 MDH1 CLDN10 FGFR4 WDR34 METTL7A IFT122 ASB9 SAC3D1 DHRS1 ENO1 DANCR SDC1 NT5DC2 FAM229B UPK1B TSPAN6 C9ORF116 METTL7B CRYM NDUFB2 HIST1H2BK AGR2 KRT8 EMP2 AADAT TSPAN3 PRPS1 TOMM40 STEAP3 VASH1 EIF3B ORAI2 EFTUD2 EMP3 ACLY NCLN PLK1 AK2 DHCR24 TOP2A TICRR ZWINT TROAP SAP30 MRPL12 LMNB1 GTSE1 CDKN3 UBE2C E2F2 KIF18B SPR SPAG5 ANXA5 BUB1B MCM2 KIF2C AURKA DLGAP5 ESPL1 CAPNS1 RRM2 SHMT1 CDC6 E2F1 BIRC5 ORC1 KIFC1 KIF4A MPND COMMD9 SAPCD2 ROGDI HSD17B10 SNAPIN CDCA2 NETO2 NME1 TPX2 CCNB1 NCAPH CDCA3 CDC20 KIF23 HJURP TRIP13 MKI67 CDC45 KIF20A SCD NCAPG TYMS PDGFD CRIP2 MANF SLC2A8 FOXM1 IMPA2 EPN3 THEM6 CYB561 TONSL PPP1R16A PROM2 HR FZD1 WWOX PRC1 PSRC1 CASR CENPA MXD3 PASK RAD54L FANCI ASF1B KIF22 GINS2 FAM83D NCAPD2 NPBWR1 SPC24 TACC3 MCM5 CENPI SPC25 H2AFX ARHGEF39 CENPM CCNF NCAPG2 SYT12 LRP8 CHAF1A SNCA DHFR IGFBP6 RAMP1 VCAN CLDN2 EPHB6 DDC PFN1 HNRNPM TUBA1B TMA7 PEBP1 THRA TPPP3 SMAD6 HPGD LYZ CTSH ACAT2 RPN1 MYH10 COX8A NDUFS3 EIF5A ARL6IP4 PSMD3 IHH CETN2 NDUFB11 HADH NDUFB7 CCT3 AQP1 MPC2 VDAC3 FASN IVNS1ABP NDUFA4 ANAPC5 DBI PGRMC1 NDUFB10 TMEM147 MIEN1 CACYBP QPCTL TMEM213 OST4 ERI3 TM4SF4 HMGB3 ATP6V0E2 NDUFAB1 CUTA MIF AIFM1 POLD2 DCXR ATP6V0D1 PSMB3 DPP3 AHCY NHP2 LSM7 PIH1D1 PCNA HDAC1 POLR2E WDR54 NDUFA8 WDR83OS AHSA1 PTDSS1 POP5 GMNN HSPE1 HSPA1A SF3B5 MRPL11 C1ORF122 LDHB SDF2L1 SOSTDC1 VAV3 RUVBL2 NUDC SRSF2 ID1 MNS1 HSD17B7 CPNE1 SQLE ID2 CDH6 FANCG MCM6 DNAAF3 MVD TCTEX1D2 BCL2L12 SLIRP SNRNP40 FEN1 ANXA10 WDR90 ELOVL6 DERL3 TNFAIP8L1 GCAT MEDAG RARRES2 FGFR3 CYS1 CDKN2C LMAN2L PCSK9 TESC TRNP1 MCM4 MCM7 FAM149A SNRNP25 ALYREF RFC5 RFC2 IDH2 LRRC45 NEB LMNB2 LIG1 RHNO1 NCAPD3 TMEM237 CAPN8 MLEC KIAA0100 UCP2 NEFL HOGA1 GALM BRI3BP TM7SF2 COX5B UQCR11 HPDL CENPV FADS2 SCGN DPYSL3 CCDC34 HSPA1B PRDX2 PGK1 SKP2 ALG1 SDHA SNRPD3 TIMM21 IDI1 PARP1 CA12 TRIM54 GBA APMAP BDH1 SPP1 COPS6 CLN6 SLC25A10 ARMC6 NUBP2 TRMU HSPB11 TBL3 FBXW9 SGK2 HMG20B FAM173A ADI1 DGCR6L TSTA3 RABEP2 POLE4 LSS MVK AMDHD2 PRADC1 ALDH16A1 TELO2 TMEM129 KATNB1 UROD TBCD SIVA1 FDPS HEXIM1 TCTN3 FDFT1 MCCC1 LRPAP1 CD320 CHDH TEX15 ACACA VWA1 DTYMK LRWD1 PGP POLR2F IGFLR1 PRKDC SLC39A4 SCARA3 KCNK2 CYP51A1 RANBP1 GCSH ICMT GJB1 F12 ACSS2 MCM3 ALDH1A2 PIN1 THOC3 POLD1 RECQL4 HNRNPAB IPO4 CENPO ENDOG TUSC2 CTDSPL ANXA9 BCKDHB FAM81A IMP3 RNASEH2C SLBP CHRNA5 GINS4 BCL7C SRPRB RPGRIP1L C1ORF53 MFSD3 AIF1L CAMKMT IL17RB SFXN2 RBM14 CAPS COMMD4 MIR31HG GPS1 MANEAL KIF12 CSPG5 DHCR7 C7ORF50 OSBPL7 KCNMB4 UBE2E3 MUM1 PXMP2 LAGE3 TMPO-AS1 HS6ST1 PAGR1 MRPL41 NSDHL CHST7 PACSIN3 CENPT CTXN1 DPCD MAPKAPK3 SAMD1 PMVK FAM173B PKDCC MMAB DSEL JMJD8 NRM HES6 PLEKHB1 EIF2B1 PCYT2 SLC22A18AS RERG TMEM141 TRAPPC2L DNLZ SLC25A1 ANAPC15 DECR2 MAOB STXBP6 LOC100294145 AGFG2 NTHL1 MRPL3 GALNT10 EBP POLR3K ZNF580 GAMT THAP11 VPS26B GMPPB SYNGR1 MARC1 MYL6B RIBC2 H2AFV TSPAN12 TMX4 PIF1 RAB36 CHCHD6 ANKRD54 DLEU1 SDR39U1 ZFYVE21 PGAP3 ARHGEF19 TUB TMEM201 RPA1 C21ORF58 ELP6 MPV17L 61 genes down regulated by MERS and COVID-19 in Calu3 cells from two separate studies genes down regulated by MERS and COVID-19 in Calu3 cells TMEM97 CENPF CALM1 TSPAN8 MDH1 UPK1B TSPAN3 LMNB1 GTSE1 CDKN3 UBE2C AURKA DLGAP5 RRM2 TPX2 CDCA3 KIF23 KIF20A CENPA ASF1B SPC24 SPC25 DHFR CLDN2 TUBA1B PEBP1 LYZ ACAT2 COX8A CETN2 NDUFB11 DBI PGRMC1 AHSA1 HSPE1 MRPL11 LDHB SRSF2 ID2 MVD ELOVL6 IDH2 LRRC45 COX5B PGK1 SNRPD3 SPP1 FDPS ICMT ACSS2 HNRNPAB CTDSPL ANXA9 BCKDHB FAM81A IMP3 RNASEH2C SLBP CHRNA5 GINS4 BCL7C 500 genes upregulated by SARS-CoV-2 in human lung tissue from GSE147507 SARS-CoV-2 infection of human lung tissue Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sgagVhu3E IL1B FAM8A1 FKBP1A FGL2 CCL2 NMI TNF DDX58 LILRB2 YWHAZ IL1A CXCL10 IFITM3 TLR4 PDZD11 CXCL16 ARRB2 TPM4 IFITM1 YWHAE LYN HLA-B GNG5 CDHR5 FAR2 F5 RAB8A TREML3P OAS1 SULT1B1 FCGR2A DMBT1 HLA-C STAT1 HLA-A IFITM2 B2M EIF2AK2 MGAM OASL USP15 ISG15 CD4 RPH3A SPI1 PLP2 MX1 CD55 BCL2A1 TPSB2 LCP1 SNTN CEACAM6 TMEM71 TNFSF10 PIGR SIX1 REPS2 HIST1H2BC MCTP2 FAM216B IGSF6 GCNT3 S100P GPX2 FDCSP METTL7B CXCL17 PNRC1 FREM2 TNS4 MARCKS STEAP4 APOBEC3A TET2 DLGAP1-AS1 HIST1H2BD CCL8 LCN2 DHRS9 HESX1 GABRP C1QC TOR1B VASP PTK2B SF3B4 CD37 VKORC1L1 MYADM HCAR2 TOP2A MILR1 VSIG10L LMO2 C3AR1 LMNB1 PLBD1 KCNE1 GLRX IFI44 RNASE2 C1QB EPSTI1 NME1 BRCA2 PADI2 GLDN HP HPR CERS6 SPTLC2 CLEC12A CHI3L1 CST7 SCARNA21 CCL4 CLC CAMP IL18RAP ABCC2 ACTB MMP25 LTF WNT7B TFAP2A ALPL MMP8 HLA-DRB5 MAP2K6 CTSC BCL3 FCN1 CBX4 ZNF385A SAA1 CD48 RSAD2 GPR65 OAS3 CD69 IDO1 IRF7 GNG2 ZBP1 SLAMF7 LCP2 SIRPB1 GBP5 TNFSF14 MS4A7 TLR1 HCST GPR84 CHIT1 FCGR1A IFIT1 ARHGDIB CLEC4A RAC2 STAT4 TNIP3 PTPRC LY86 CLEC7A IGF2BP3 CTSS FCER1G S100A9 ENPP6 IFIT3 RTP4 SFT2D1 CYP7B1 OAS2 PHF11 XAF1 APOL6 CCR1 CXORF21 GBP4 CYBB IL1R2 GPR141 IL1RN IFIT2 HBB CLEC4E PLAC8 TMEM52B HERC6 CLEC4D IFIH1 TNFAIP6 STAT2 PML CLDN2 CCL11 TREM1 NAMPT PARP9 SAMD9L GCH1 HSH2D CASP4 BASP1 CCL19 C5AR1 CSTA UBE2L6 SP110 IRF2 FTH1 PSENEN PFN1 LY6E ATP6V0C CRYAB IRF9 GBP3 DAZAP2 SFTPA1 SCGB1A1 SERPINE2 GABARAP IFI44L LITAF SERPINB9 SH3BGRL3 JUND CD74 TYROBP IFI30 CFL1 IL2RG ALOX5AP HCK NCF4 SAT1 NOP10 GTF2B CD164 CNTN1 RBM11 COL9A2 C1ORF194 SAMSN1 ZC3H12A LST1 SIGLEC7 BPI TRIM22 CR1 S100A12 CYTIP PGLYRP1 DCUN1D3 LRRK2 NTNG2 SEZ6L2 ADRA2A ANP32A PSMA4 MPV17 S100A11 SF3A2 PSME3 DYNLT1 CKLF SNX10 MXD1 PDE4B FLJ45513 HAMP NEAT1 MNS1 MSMO1 C15ORF48 ANXA2R CTF1 P2RY14 P2RY13 TNFSF8 S100A8 CASP1 CSF3R GCA TRIM21 ZC3HAV1 SELL TRIM5 PCGF5 POU2AF1 BCL11A WAS CTSE RHOH STAP1 OLR1 FPR1 CD38 PDGFRL PTMS ALDH3A1 HS3ST3A1 BIN2 CXCL11 ZMYND12 RP2 IFI6 LY96 MNDA CHRAC1 LAMP3 DDX60 RNF19B C19ORF66 LGALS9 TNFSF13B XRN1 MX2 IFIT5 HERC5 DDX60L SAMD9 GBP1 PSTPIP2 UCP2 CEACAM1 KLHDC7B ARL5B PATL1 NAPA SP140L C1S SOD2 VNN2 TRIM38 RABGAP1L PIK3AP1 RAB8B ARSE SERPINA1 SERF2 SRGN FCGR3B GPSM3 CSF2RB CDA CD53 GNLY PLEK LPAR6 EVI2B AIM2 FCGR1B SPRR2E HBA2 HRASLS2 APBB1IP NCOA7 VNN3 ZDHHC19 AMDHD1 LOC643802 HLA-J CA1 CORIN FCAR CDH2 CCL3 GATA1 CCL7 TIMM23 USB1 CLECL1 PILRA SIGLEC5 LILRB3 LILRA6 LILRA5 FGR STX11 GK FCGR3A SIGLEC14 AQP9 DOK3 CARD16 BCL2L14 CASP5 HBA1 TRPA1 CA12 PELI1 SP140 PI4K2B VSIG1 CAPZA1 C4ORF3 CCL18 BLOC1S1 FFAR2 KCNJ2 RBP4 SLC39A8 MGC12916 MROH8 CMC2 TREML4 NME8 CLEC1A TLE4 MCTS1 TAOK3 WIPF1 MIER1 POPDC3 CPLX2 IQGAP1 G6PD PIM2 F8A1 CYP19A1 RNU4ATAC OR7E14P LINC00605 DBNDD1 GMFG ACSL1 RGL4 HIST2H2BE BCL6 CARD17 LINC00639 TFEC ST20 RNU12 HCAR3 NEXN DAPP1 CCDC114 C20ORF203 YPEL3 AGMO RNU6ATAC LILRA1 LOC399715 OLIG1 STK24 PROK2 DNAH7 TENM1 LOC388813 EIF1B CHI3L2 RNU11 NBN ALPK1 ANKRD22 FCGR2C LBP GBP1P1 RGS18 HNRNPC CACNA1A KCNJ2-AS1 ATP7B ITGB2-AS1 STRN4 CYSTM1 SLC9B2 KCNH7 TPP1 JAK3 FHL3 MAP3K13 SYN1 MDH1B GAPT TARP CCDC71L VTRNA1-1 NFKBID HSPB6 SNORA48 TMEM154 SNORA74B RTN3 CEACAM3 KLK10 PPDPF C9ORF66 DNAAF1 SMAP2 PSEN1 SFTPA2 SLC26A8 CDR1 FLOT1 500 genes down-regulated by SARS-CoV-2 in human lung tissue cells from GSE147507 SARS-CoV-2 infection of human lung tissue Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sgagVhu3E GAK CANT1 BCL2L1 EEF1A1 MPHOSPH10 ZC3H7A EGR1 FBXW5 SUN2 BCAR1 DDX5 TUBGCP2 MYO1D BAIAP2L1 GOLGA3 UBXN1 TMBIM1 RASA3 CUL1 NDRG1 TUBB4B MRPS2 BAG3 TUBA1A HMOX1 DNMT1 EIF4E2 TUBA1C TUBA4A SFN MEPCE HERPUD1 PES1 PPIG MOB2 HSPA8 USP7 H2AFJ ZBTB44 SCYL1 SGTA PLEKHO1 BAP1 BCL2L2 NEBL RPL41 RPS3A SLC25A4 RPSA ABLIM1 MEIS1 STARD10 CCND1 TMEM109 CD2BP2 PIEZO1 USF1 MICAL1 ATG4B DPP7 AKAP1 XAB2 ZC3H7B LDB1 SEC24C USP19 DNAJB2 ZDHHC7 QSOX1 BSDC1 EIF3B PLEKHO2 ZSWIM8 NDST1 SIN3B APH1A SMAD7 ITPKB PPP6R2 DDB1 ADAM15 KIAA0930 ARHGAP29 ACVRL1 MAFG CCT8 DOCK1 SMTN ADAMTS2 GRB10 HEXB UNC13B SH3PXD2B PRELID1 SEMA4C SLC25A29 PBXIP1 MYC GADD45G B4GALT3 KLF13 TRAK2 TGFBR2 PIK3IP1 GADD45B TRAK1 STAT5A PSMD6 SEMA3F ALS2CL ITPR3 PYGO2 TFIP11 WDR37 FZD4 FIBP HDAC3 CTR9 RGS3 UPP1 EDC4 C2CD2 PHC2 CYP1A1 PDE2A RPS28 TNS1 IER2 FOS SGK1 EIF3G DUSP1 ID3 EGFL7 GATA2 PXDC1 JUN CLDN5 CTGF RPL3 RPLP0 POLDIP3 SFTPC MAT2A CRIP1 LUC7L3 RPS5 NR1D2 VPS28 PPP1CA C1QBP NDUFS6 TCF21 HCFC1R1 SH3PXD2A EFNB1 CAMTA2 KLHDC3 HEXA RAPGEF3 ERRFI1 LBH STK38 SERPINB6 SELENBP1 SLC25A3 TPRG1L CCNL2 CTDSP2 FAM160B2 GUK1 S100A13 MYZAP CCDC85B RRAD AKAP17A SLC25A25 STARD9 MYCT1 F2RL3 TCERG1 GJA4 ROBO4 SNHG15 STC1 SERTAD1 MAFF FOSB ZNF263 CIB1 TMEM208 CKB NRBP1 ASL C12ORF57 EBNA1BP2 BCOR TSPAN4 PSMC1 MGLL TUBB6 GNL2 SF3B5 SPSB3 DNAJB4 ODC1 EIF2B5 MFAP1 MLH1 RANGAP1 PAN2 ARRDC2 ITPKC BLCAP GALNT18 RND1 DEXI MUL1 NUDCD3 PPP3R1 RNF31 DLL1 MEDAG DLST INPP1 RARRES2 GOLGA8A PER1 FAM13B MCM7 AMFR DNAJC7 KIF3B ATRX EIF2B4 ST6GALNAC6 SLC25A36 RALBP1 ARPC1B ENO2 PDXK THAP2 RALGDS GRPEL2 NR4A1 TMEM255B CSPG4 MCAM COL12A1 HLA-H GNA12 GET4 ANAPC11 EXOSC7 TXLNA CTCF CDK9 BCR KDM1A PRMT1 PGF NFATC2 MMP14 QARS PRKAB1 GRSF1 SPRYD3 SEPHS1 AIP CD82 PSMC5 DDX56 MAPKAPK2 SAE1 PSMC3 TNFAIP1 CYTH1 ROBO3 WIPI1 FAM32A SLC35A4 ZNF330 CHMP1A AHNAK CDC42BPB CDC37 CIRBP URGCP EHMT1 MPHOSPH8 ANKZF1 FAM118A RASSF1 ARHGAP10 PTCD3 DHX29 ZMYM2 DLL4 HMGXB3 ACTR1B MEF2D ULK3 PLEKHM1 ITPA ENG PODXL PHLDB1 MLXIP THOC6 ASB1 DDX39A MFNG MADD TRPC4AP HDAC7 ZFAND2B PARVB TANC1 FOXK2 RRP1 INPP5A ARHGEF7 E2F4 ZSCAN18 SSH2 PLXND1 PYCR2 PMM2 NOP56 RNMT PRDM2 PPP1R14B SKIV2L CXORF40B RRP12 ATP6V0A1 KCTD20 ATP6V0A2 CYC1 PXDN DCAF5 ENTPD6 CRY2 MYO9B CC2D1B RAPGEF1 SERTAD3 EPC1 GGA2 BRD9 ILVBL MAP4 LUZP1 MDC1 NFATC4 TAF1 HARS2 ELK3 SNAI1 PQLC1 SLC38A5 RXRB TTC7A METTL3 DAPK3 S1PR2 VPS13D MOAP1 SLC39A7 KCTD10 PCDH12 RHBDF1 KANK2 SRCAP CCM2 AMOTL1 AGAP3 ACP2 TSR1 TIMM13 FARP1 PPP1R13B FBXO31 TSPYL2 INPP5K LETM1 HBP1 UROD CHFR CTPS1 ADCY6 DKK3 VPS54 SMPD4 C19ORF48 NCAPH2 RBM6 MICAL3 SSH1 DST PELO STARD3 ADCY4 NOC2L TCF25 DTX4 GNL1 MFN2 TBC1D9 OSBPL5 ZNF160 UBE2J2 SLC9A1 SUN1 PDGFRB RAF1 PLEKHM2 NDUFA11 PLXNA2 SPRED1 ABR XPC NOL8 NISCH LRRFIP1 ABLIM3 KAT5 VSIG2 UTP6 RRP7A SASH1 URB1 FLNC LCN10 TBCD LRRC32 FHOD1 SGSM3 SLC25A44 GLT8D1 C6ORF106 USP22 EDC3 VPS37B GAS6 TTL PCID2 SNX11 LZTR1 BAALC NES MBIP LMBR1L TSSC4 CTTN ITPR1 SIVA1 UCK2 NASP ARHGEF15 DOCK6 TXNDC11 DDX42 PRKY GMPPA PPP1R12A PPP1R16B AFG3L2 SREK1 RSAD1 LRRC47 SGSM2 PSMD2 NAP1L4 HIPK2 FDPS GUCD1 FAM219B ZNF451 SPHK1 PCDH1 RBFOX2 LRIG1 RPS6KA2 WDR74 WBP1L ATP8B2 FAM214B MAF1 IFT43 PEX5 ERCC1 ARFRP1 SPG7 CCDC130 FXYD6 XRCC6 DCHS1 NAB2 ARAP3 500 genes up-regulated by SARS-CoV-2 in human NHBE cells from GSE147507 SARS-CoV-2 infection of human NHBE cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/BMjl0zF19 MAOA IL1B BIRC3 IL6 HYOU1 TNF CXCL5 PPP2R1A MOGS DDX58 IL1A RRP9 IFITM3 MAST4 CXCL16 ANXA3 IFITM1 PGLYRP4 LYN NEDD9 TUBB4B LAP3 TUBA1A SMAD3 NFKB1 OAS1 TUBA1C ATP1B1 FN1 TUBA4A STAT1 TRIM25 TRAF3 IFITM2 VARS EPB41L3 USP54 PLAT MSN CXCL2 ISG15 CSF2 MX1 SIPA1L1 ZC3H12C HYI AFAP1L1 TLCD1 ALDH1A3 BCL2A1 MYO10 MUC21 CXCL1 CXCL6 ASS1 ENTPD3 MYO1B IFI27 KRT4 KRT17 TTC9 S100P DUOX2 OSMR SERPINB2 SPRR1A SPRR2D EVA1C PRDM1 CRCT1 ADAM28 SLPI NDRG2 SGPP2 LCN2 GABRP SPRR1B RELT OGDH TNFAIP2 TOR1B HBEGF TYMP BST2 ITGA5 ACLY NLRP1 CCT5 PNP SDC4 MRPL12 TUBG1 GLRX LDLR IFI44 CES1P1 CES1 EPSTI1 SMTN PDIA5 ALOX15B SH3PXD2B ARNTL2 PRELID1 SLC43A3 IL7R G0S2 PTGS2 AKAP12 IGFBP3 B4GALT1 SLC2A6 B4GALT2 MYC BMP2 MMP1 SERHL2 STAT5A EDN1 PLAUR GJB3 RHOV LAMB3 WWC1 SEMA4B SULT2B1 TRIM16 FAM83G EREG WNT7A MAP2K3 MLLT11 UPP1 CTSC FAM50A BCL3 HELZ2 NUAK2 HSD11B1 SBNO2 SAA1 OAS3 IRF7 CFB GBP5 TNFSF14 TAP1 CCL20 LPXN IFIT1 GPR176 CORO1A SLAMF9 IL36G S100A9 IFIT3 OAS2 C3 XAF1 CXCL3 PSMB8 C1R KYNU IL1RN MRGPRX3 UPK2 PTAFR TGM1 HERC6 IFIH1 MLKL HAS3 STAT2 PML SOCS3 NFKBIE NAMPT RHCG PARP9 PARP12 SAMD9L HSH2D TMEM171 XDH SERPINA3 LIPG INHBA IFI35 PARP14 FOSL1 SAMHD1 F3 CSTA UBE2L6 ANGPTL4 PLAU FST CSF3 MICALCL ETS1 PSME2 IER3 TUBA1B DUSP1 TGM2 HMGCS1 ICAM1 DTX3L NFKBIA IRF9 PSMB9 DRAM1 VEGFA BTG1 IFI44L PFDN6 TUBB CD74 ATF4 PQBP1 FXYD5 ERRFI1 TUBB2A PDPN EHD1 FNDC3B ANXA1 ELOVL1 EFHD2 SAT1 MARCKSL1 RFTN1 TMEM147 POU2F2 ZC3H12A FAM167A PPP1R15A TRIML2 FUT2 S100A12 MYPN TNFAIP3 ASB2 SERPINB4 PLA2G4C ARHGAP25 STC1 LIF CSRNP1 MAFF NFKBIZ ALAS1 PDZK1IP1 HMGB3 MMP10 SRM C1ORF74 PI3 HSD17B2 CCT7 AKR1B1 NAA10 TUFM CDC25B RANGAP1 EFNA1 SAMD4A TNFSF15 HYAL1 RIPK3 HDGF SQLE HIVEP2 MMP9 NEURL1B C15ORF48 RND1 VEGFC CSRP1 STAP2 TAP2 FAM57A S100A8 SLFN5 TLR2 MMP13 SMOX TRIM21 BID TRIM14 MAP3K8 IRAK2 PCSK9 VNN1 IFI6 IL32 LAMP3 TFPI2 SLC25A28 LGALS9 MX2 ADRB2 KIAA0100 PSTPIP2 GJB2 LAMC2 KRT16 RELB MICB CLUHP3 TICAM1 DUSP4 PRSS3 COPG1 CSTB RBMS2 C1S SOD2 SH3KBP1 TRIB2 BPGM GTPBP2 ENO2 ACTN1 SERPINB1 CDA LTB P2RY6 KRT6B CHST2 ZBED2 CDC42EP2 SERPINB8 SEMA7A ITGB3 COL12A1 ADAM19 TUBB3 IVL ADAM8 PLSCR1 SPRR2E KRT24 SPRY4 SAA2 NCOA7 SLC6A14 C1QTNF1 ZFP57 CWH43 VNN3 SLC13A5 IFNGR1 GNA12 MTSS1 IKBKE USB1 IDI1 NAGK TNIP1 NCF2 OTUB2 IFNGR2 NFKB2 HARS HMOX2 CD82 NECAP2 PSMC3 TNFAIP1 STK10 PPP4R1 IRAK3 ARF4 CD99 HEPHL1 KRT75 STK25 TINF2 TPCN1 ST3GAL5 PLEK2 EPHA2 BTG3 CDCP1 PLK3 FLII PODXL LSS MYEOV MGC12916 HCAR3 DAPP1 HDAC7 RRP1 E2F4 PXDN LETM1 CTPS1 UCK2 PSMD2 FDPS MICA TNIP2 TNFRSF10A SNORD43 RAET1L DTX2 AMPD3 FUT3 CDC34 TGFA SEMA6A FERMT1 PDGFB PLEKHG7 HMGN2P46 MYO1C BIK ADAMTSL4 HK2 ZNF169 ULBP2 OSBP2 CYP27B1 TNC POLB PPIF POLR3E STARD5 SLC11A2 RHOC ARHGEF2 TMEM51 KRT23 FLNB ANXA9 KLHL18 NOP2 SH3RF2 ZNF319 CEACAM19 ZSWIM4 C6ORF223 FSTL3 SLC25A37 RAB11FIP1 NRCAM DHCR7 THSD1 ISG20L2 MPV17L2 NBPF14 IZUMO4 PWP2 N4BP3 CSGALNACT1 RHOF MICAL2 FAM83A HHIPL1 FEZ1 GJB4 ANXA6 CDRT1 MRPS21 LGALSL CARHSP1 FHDC1 S100A7 TGM5 SHB RNF122 RBFA ZP3 C15ORF62 SPRR2A GNA15 PRELID2 CSNK1E LIG3 KIF3C AFAP1 COL8A1 MEG3 MFSD2A STOML1 ZG16B DDX28 B4GALNT2 CCDC24 FAHD2A NCCRP1 NDUFB8 KCTD11 TRIM47 LTBP2 IGFL1 TEPP FNDC4 500 genes down-regulated by SARS-CoV-2 in human NHBE cells from GSE147507 SARS-CoV-2 infection of human NHBE cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/BMjl0zF19 CNTRL PTEN MME TP53AIP1 SCN2B HOOK1 CENPF VIPR1 CEP68 NCKAP5 ITGA4 PTPN4 PLEKHA5 CREBL2 SCP2 NUDT12 MPP7 METTL7A PMS1 CPT1A GPR155 IPP CAV1 RNF128 SLITRK6 CLCA4 OSBPL6 RPL9 SLC15A2 C1ORF21 FGFR2 GULP1 MT1E SMPDL3A PBX1 RHOBTB3 TRIM2 SOX2 DSG2 PLCE1 FAM214A CYBRD1 SATB1 SYTL5 WDR63 KRT15 PRSS16 MUC16 CLCA2 FMN1 ZNF507 RPL39 SSBP2 EXPH5 PRSS23 EYA1 MBNL2 ABLIM1 PSCA PTPRZ1 ANK3 GCNT4 VTCN1 SEL1L AQP3 PROS1 RHOB ABHD2 TOP2A CCNA2 LMNB1 CREG1 NREP SCPEP1 FRRS1 DEPDC1B HMMR ADPRH ARHGAP29 FKBP5 DLGAP5 GPNMB CDK1 CCNB1 ANLN OLFML2A CBR1 EPS8 CEP55 CERS6 KCNMA1 GNPDA1 ZNF365 ENPP5 PER3 FAM131B PTPRS TCN1 CAMK2N1 BMP7 PKD2 BMP4 ZNF180 CHURC1 FOXO1 IMPA2 MLPH SYT8 APPBP2 DSG3 WLS FZD1 KITLG CLU SFRP1 FRAT1 MAF EGFL6 TMEM60 FGF1 NR2F2 F2R DCK SOX6 TBC1D8 SORL1 MAB21L1 MEF2A ERF SMC2 CENPA CREG2 FANCI APOD SLAMF7 CKAP2 CENPP CENPE GEN1 SLC7A8 CD86 POLE2 FAM181B AAK1 STON1 LGI3 NFIL3 SLC7A11 GBP6 TLR3 MAMDC2 CALML3 ZNF704 DBP ACER2 THBD SPARC ANAPC13 HPGD CTGF NPNT LIMCH1 CTSH PDE5A NR1D2 TP53INP1 PDCD4 TMEM50B TSC22D3 SP3 DYNLT3 RGCC MYLK MYLIP TCF4 GNS LXN NRP1 CETN3 CD36 TNNI2 DEK ARRDC4 ADAM32 RAB30 MXRA5 CCND2 C21ORF91 HMGN5 CYP4F3 FLRT3 IRF2BPL DLG2 CCDC58 ANXA2P3 SERINC1 HSF2 CXXC5 PPP1CC EXTL2 LCLAT1 LRP11 AGPAT5 SNHG8 GNA13 DNAJB4 SOAT1 VAV3 SGMS2 MUM1L1 DUSP10 SKA2 APOBEC3C PPM1H NEAT1 MN1 PRR15 CREBRF FAM129A SPESP1 ELOVL4 ABHD10 C2ORF81 LGALS8 PDK4 FAM161A POU2AF1 MUC20 CCDC15 ALDH3A1 FBLN2 NID1 GOLGA8B PTGR2 SYT16 BBOX1 MT1X MCM4 ZNF566 MBNL3 SMC3 WDHD1 SLC26A2 SMAD5 SEMA3E PRPS2 SCOC RARRES3 PIK3R1 PCYOX1 C1ORF210 ATRX ZNF468 PRKACB FNIP1 ANKRD12 FAM110C WEE1 RRAGD BLNK RPL17 PUM2 ADD3 ZNF397 SESN1 CEP152 KLHDC8B PIK3R3 FLRT2 FRY FHL2 CHKA NT5DC3 PLA2G4F APBA1 CXCL14 DSC2 KRT6C STK32A TGFB3 NHLH2 POT1 AASDHPPT RMDN1 NANOS1 CAMK2D BACE1 EEA1 HFE PPARGC1A TIMP3 FAM111A ARRB1 IFITM10 SLC35F5 GALNT1 SCD5 ALAD CITED2 ALDH3A2 GGCT EPHA4 ATP7A ZNF268 ANKH SYNE1 PRODH CYB561D1 EPHB3 ACSL1 PPDPF DST SASH1 HIPK2 IL6R PRCP GHR MTUS1 GCLC HSD17B3 SYDE2 ADCY1 CPA4 SCNN1B MEGF9 TRMT1L FAM13C TCHHL1 SERPINB13 CDH10 CDK19 PCM1 TMEM168 ANKAR HLCS GSR BCL2L11 SLC9A9 WDFY1 RAB26 FBXW7 TMEM106B SESN3 ATG9B TBC1D15 SPTLC3 FMO5 MAP3K2 LMO4 SENP8 RANBP6 ZCCHC10 ZNF639 TSEN15 CLDN23 CTDSPL PALMD LYST TIAM2 TNKS2 CAPS MAOB LOC100294145 GAMT STRBP TLL2 MIER3 LOXL4 KIAA1211L MYSM1 CCDC60 TINCR FAM49A DIP2B KLHL4 UBA5 EPGN TMEM135 MANBA LYPLAL1 NFIX LOC286437 PFKFB2 SLC44A5 REV3L TENM3 FPGT DSC3 SEMA6D PXMP4 LINC00672 UFL1 ACVR1 TBC1D5 MAN1A2 LRMP TFCP2L1 DZIP3 ZNF395 VSNL1 DPY19L4 LCA5 MAP7D2 PUS10 PGAP1 MTSS1L ESPN TMEM99 EFCAB7 CCDC121 DCAF17 ANKRD50 ENDOD1 ARHGEF6 RNPC3 LANCL1 VANGL2 EBAG9 KPRP MBOAT1 ZBTB7C MIR221 PTAR1 NMRK1 CPD SLK FAM84A FAT2 DCUN1D1 SDCBP2-AS1 DTD2 UBN2 RBM20 SULF2 CPE PHTF2 TMEM131 SSX2IP SLC35D1 PARD6G KLHL13 ZXDA TUSC3 RAB15 ANKMY1 PADI3 ADAM23 FAT4 VWA8 FAM43A CCDC6 STK17B PPP1R3C CASD1 TLK1 CAPN7 ZNF579 ZNF607 ZNF608 MAN1C1 FRMD5 GPSM2 VGLL3 CNTNAP3 HEG1 STON2 LY6D PINLYP PCDH7 PHIP MFAP3 NCR3LG1 DENND4C UST PGRMC2 FAM198B CCDC126 MANEA C8ORF37 TROVE2 ABHD13 CMYA5 YTHDC2 LPCAT3 AEBP2 CEP44 CRNKL1 CCDC138 LMBRD2 SRGAP3 CD109 ZNF718 LINC00113 MCOLN3 GXYLT1 LOC440028 FAM171B EIF4EBP2 ZNF488 CCDC14 500 genes up-regulated by SARS-CoV-2 (0.2 MOI) in human A549 cells from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/koQnoZg81 TM4SF20 SUMO1 IL1B TBCA HDAC2 RSRC2 IL6 HSPA5 CCL5 SUMO2 UGT1A7 NMI NUP54 CXCL5 SLC27A2 ITGB1 DDX5 DDX58 EIF2S1 IL1A DDX21 SHQ1 IFITM3 SLU7 ANXA3 IFITM1 AP3B1 DDX1 HSPA4 HLA-B LAP3 EHBP1 HSP90AA1 LARP7 FAM162A NCK1 OAS1 RDX HLA-C FN1 PLOD2 STAT1 TRIM25 IFITM2 B2M PRIM1 EIF2AK2 USP48 OASL EIF4E CXCL2 PPIG ISG15 FRMD3 PAICS MX1 MYD88 NOL7 RBM39 PAIP1 CD55 BCL2A1 MNAT1 SLITRK6 CP CXCL1 KRT18 RPL9 ASS1 MYO1B IFI27 DUSP16 TNS4 CFH C1ORF116 EVA1C SEMA3A SLPI ZNF467 ISG20 LCN2 EHF TAB2 PARP10 LGALS3BP APOL1 PIGK TYMP BST2 SLC16A3 RHOB EXO1 C5 HSD17B4 IFI44 EAF2 FAM72D CCT8 LTA4H SLFN11 CEP55 BATF2 LDHA CA11 PTGS2 FAM131B IGFBP3 ZNF184 KLF10 CDH1 EDN1 SULT2B1 EREG DKK1 GMPS NUCB2 HIF1A HELZ2 HSD11B1 PDLIM5 SMARCA1 SAA1 OAS3 IRF7 CFB FANCI NLRC5 TAP1 CCL20 ERCC6L CKAP2 IFIT1 STAT4 CTSS MASTL TNNI3 IFIT3 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 PSMB8 APOL6 C1R KYNU USP18 CMPK2 IFIT2 IFI16 CLEC4E FGL1 HERC6 IFIH1 CCDC18 STAT2 STON1 CACNA1G PML PLEKHA4 FGG ADAR NAMPT PARP9 PARP12 SAMD9L SERPINA3 IFI35 PARP14 HAS2 SAMHD1 UBE2L6 UBA7 SP110 CSF3 RBP7 TSC22D1 PSME1 PSME2 THBD UQCRB IER3 ICAM1 DTX3L NFKBIA IRF9 GBP3 CYB5A PLIN2 EFEMP1 LUC7L3 IFI44L DNAJC8 PAIP2 BNIP3 FHL1 FDX1 CHORDC1 ERRFI1 DNAJA1 PSMA6 FSTL1 SELENBP1 THEMIS2 PHLDB2 SAT1 SUB1 CACYBP DEK ESF1 FGB AOX1 SYT1 SERPINI1 PTGER2 TNFAIP3 STC1 FLRT3 TAF1D ZNFX1 HAT1 SUPT16H MMP10 PSMA4 HSP90B1 SARNP CNOT10 MTX2 TTC1 SUCLA2 CCDC58 NOP58 PI3 ANP32E PCNA C2ORF74 MSH2 SMARCA5 ZDHHC6 PAM GJA1 SSB STEAP1 BZW1 RPAP3 PNPT1 MAP4K3 AKR1B1 CBX1 USO1 GNL2 CWC22 ERVMER34-1 MXI1 MORC4 CCDC117 TCP1 INTS6 PDE4B ITIH2 ID1 MNS1 GSPT2 PIR MAP2 C15ORF48 GLCE SERPINB7 MLXIPL ODF3B MKKS NNMT TAP2 EBI3 TRIM21 RNF31 CREM ZC3HAV1 TDRD7 TRIM14 PDK4 MAP3K8 MORC3 ELOVL6 OLR1 TESC IFI6 PTGR2 PRPF38B BMPER IL32 PSIP1 LAMP3 DDX60 SMC3 WDHD1 TPR CCDC77 TFPI2 DNAJC7 C19ORF66 SP100 IFIT5 HERC5 TRANK1 RPL22L1 DDX60L SAMD9 USP44 GBP1 CASP7 EIF5B GINM1 ZNF624 IGFBP1 CCDC91 XRCC4 MAP3K14-AS1 THOC2 PLK2 CTNNAL1 NOSTRIN NUDCD1 SP140L C1S SOD2 BLZF1 CA9 MMD CASP8 MBD2 ADAM10 TRIB1 STK17A PAPPA TMEM130 PLSCR1 NCOA7 RARRES1 IFNGR1 PGK1 ORC2 TANK LARS MLLT3 B4GALNT4 GRSF1 FKBP14 AK3 APIP MCFD2 DMC1 POLR3G FIP1L1 FAM114A2 KTN1 KCNJ2 NEMF SNAP25 REV1 BCCIP C9ORF64 LTV1 ZCCHC7 NSRP1 SLC10A7 MSH6 CLDN1 TIGD2 CEP63 STAU2 VEZT GPCPD1 RBP4 ERAP1 LINC00473 MED6 DDX50 USP8 RBBP6 REC8 KIN SYCP2L EIF2AK1 SMIM3 CUL3 BBIP1 NYAP1 NFYB U2SURP DNAJB11 USP53 C4BPA PTER NT5C2 ZC3H15 FLJ37201 RPF1 DNTTIP2 PTP4A1 EIF3J PDIA3 ARHGAP24 ALDOC ZNF430 ACSL4 BTG3 ZNF326 GNL3 DPM1 USP3 KCNJ6 KRT222 DNAJC21 PON2 FILIP1 GTF2E2 MTA3 CEBPZ ZFP28 SNORD76 STT3B PRAME TXLNG ZNF558 DHRS4-AS1 C2CD4C SNAPC1 USP16 WDR75 CCAR1 CBWD2 ELAC1 TMEM123 WDR43 SOCS6 ANKEF1 SUSD2 PTCD3 FAM49B SNORD26 AKAP10 PNMA2 SLC39A8 DNAJC2 CCNYL1 P4HA1 BRIX1 GTPBP10 PDE1A WBP4 DHX29 SPATS2 ZSCAN30 HSPB11 PTPN2 CCNT2 TEX9 ZNF518B HNRNPD PITPNA-AS1 HERC4 MRPL33 ANKMY2 PTPN12 PLA2G4A ING2 THEM4 GOLGA4 TIGD7 CPSF3 CATSPER2P1 SMIM13 HLTF CWC15 TMCC1 KCTD6 FGA LLPH IFT81 SUZ12P1 SHOX2 SMS LRRC49 ZMYM2 CPS1 ZNF680 LOC374443 RIOK1 MSL3P1 CDCP1 THOC7 PPAT PPP2R2A MIOS GREM1 NUP62CL GABRA5 MARCH7 500 genes down-regulated by SARS-CoV-2 (0.2 MOI) in human A549 cells from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/koQnoZg81 SLC36A1 PTPN14 MVP ANPEP SQSTM1 SPTAN1 STX3 TRIB3 TSPO SLC16A8 SLC22A18 A4GNT PMEPA1 ADA NPTX1 SIRPA SLC9A3 HMOX1 SERPINE1 TCN2 MTMR11 COL4A2 CTSD COL4A4 SFN MGAT4B RETSAT MEPCE PEPD PXN ZNF575 PLB1 TLN2 FRMD8 PLEC NEU1 MXRA8 ADHFE1 PLEKHA7 SAT2 GSTZ1 SAC3D1 NAGLU DANCR NT5DC2 KRT4 RAB40B NDUFB2 KIAA1217 MZT2A FNIP2 SLC2A1 KCNQ1OT1 TAGLN2 NADSYN1 MAPK8IP3 VPS37C ARHGEF10L HS1BP3 VASH1 DNAJB2 CAD CORO1B LMNA URM1 ORAI2 KCNAB2 INF2 TOLLIP SLC1A5 ABHD2 SLC38A7 MARVELD1 CORO2B MAFG SAPCD2 UAP1L1 TP53I3 TRPM2 SNX8 PRELID1 LINC00482 GNPDA1 TNRC6C MSC YPEL1 SOX13 COL1A1 CILP2 PKD1 EP400 SREBF1 AP1M2 CEP170B CARD14 RHOD WNT4 WNT9A NAV2 DVL2 DACT1 ARHGAP1 HERC2 UPP1 TRIOBP DYRK1B NBEAL2 RERE RNF44 CYHR1 MNT LFNG ULK1 SETD1B ATG2A MXD3 STAG3 PODNL1 IQGAP3 PREX1 PHF19 EFNA2 IGDCC4 LRFN4 AKR1A1 ADAMTS15 RPL10 TAGLN ISCU NUPR1 NSMF VIM SH3PXD2A IL3RA MXD4 WNK1 LBH PSKH1 FASN TPRG1L GEM FAM43B DDIT3 SLC25A25 TGFB1I1 DGKQ PPP1R15A QRICH2 COL20A1 PLA2G4C RTN4R VASN FOXK1 L3MBTL1 CLN8 BBC3 NEURL3 FAM161B CHAC1 WBP2 ATP6V0E2 CIB1 TMEM208 PTRHD1 ATP6V0D1 COPRS SPRED3 DCTN3 TIMP2 WDR83OS SUSD5 CXXC5 BEX2 CDK4 ARHGEF18 PLEKHG6 SRPK3 LENG8 COL7A1 VEGFB ITPKC NDRG4 NEURL1B PRRT2 MAP3K14 CHRNB4 FAM110A ITGA11 GJD3 CCDC78 GRIN2C C19ORF71 ACAP1 GCAT CDKN2C CYP4F11 PVRIG TESK2 CLDN14 ACP6 LONRF2 PLEKHA6 PDZK1 AHNAK2 MIR22HG CNNM3 ZBED1 TCTA TPRA1 DCST2 HERC1 TRPV1 ETS2 RRAGD VAT1 CERK COPE DYSF SNN PDXK MEX3B BMF LMCD1 LPIN1 ZNF469 ASH1L-AS1 OSGIN1 TNFRSF10D ADAM19 PKD1L2 LOC284454 NUMBL ESPNL ADRA1B IRAK1 HPS1 DOK3 NPC1 AGO2 IFITM10 CARS2 COQ4 RYR3 SLC35A4 NXNL2 AP5Z1 AHNAK CLCN7 ALDH3B1 LTB4R PLEKHJ1 ABHD4 ANKRD11 NACC2 FLCN TSPAN1 INPP5E CDH4 SLFNL1-AS1 NDOR1 NPAS1 DMPK CTAGE7P CDK10 DLL4 SPNS1 HMGXB3 TBL3 ACTR1B CAMKK1 KLHL21 COMTD1 PMF1 OBSL1 SCNN1D MEGF6 MEF2D RAP1GAP FBXW9 HTT JRK SGK2 KCTD7 ANKH ARID1B KIAA1024 MZT2B GGT8P AACS CEMP1 BCRP3 PAPLN MAP3K3 KCNC4 ADCK5 PRKAR1B MRPL23-AS1 SRRM2-AS1 ASMTL-AS1 ART5 HMG20B MIR3176 PINK1 ZNF524 ATXN1 TSPAN10 WDR81 FIZ1 FAM173A BCAT2 PGPEP1 BOLA1 TEP1 CYB5RL FLJ42627 TRIP6 TMEM91 PLCXD2 IGSF9B CCDC17 HOXB-AS3 GGN PCDHA11 MEG9 SYNE1 MDGA1 SLC16A13 ACAP3 ADI1 NEU4 ZNF324B ZHX2 PEX10 RALY RAB40A DUS3L PCDHA12 LOC100287036 ULK3 PRSS53 HERC2P3 HAPLN3 LOC646762 PCDHAC1 PPP1R3B CLTB MATN2 FAT1 DGCR6L GPRC5C ASNA1 PLEKHM1 HOXB6 STOX2 EEPD1 ABCB6 PTCH2 MARCH4 P2RY2 DDA1 PLK3 BEST3 ITPA VPS18 HECTD3 PEMT C16ORF58 SHH GAL HDAC5 FLII OTUD7A SLC7A11-AS1 WASH2P LOC100132356 NOXO1 RRN3P3 MIR600HG PRODH NR0B1 CHST3 APC2 IPO13 ENG NLGN3 EML5 TSTA3 NUDT17 PODXL LRP3 UNKL AKAP13 RABEP2 P4HTM TRAPPC6A POLE4 CHGA GLI4 PACS2 PRIMA1 SYNE2 AMH PHLDB1 GNPTG KIRREL3 CA5BP1 MAZ COL27A1 KCTD15 FA2H ATP9A SYNM NUDT14 SIRT7 SLC39A13 FBXL8 MLXIP LSS UCKL1-AS1 BAIAP2 TTLL12 RNF224 STX1B TAF1C THOC6 ZNF219 FAM102A MYEOV BTBD9 MVK SMPD1 AMDHD2 METRN FDXR KLHDC7A LOC646214 NCOR2 ASB1 IGLON5 RNPEPL1 CAPN10 TRABD2B SMPD3 POLR2A FBXO10 PANX2 PRADC1 SH2D5 CYB561D1 ATP13A1 CRTC1 DGCR9 SMIM5 MBD3 TET3 RPS19BP1 FBRSL1 FAM174B ARFGAP2 DSCAML1 FASTK FLJ16779 NIPAL4 PCDHGC3 MZF1 MFSD12 MRPL54 LOC100289230 C10ORF95 MPC1 PRRT3 TBC1D7 RHOBTB2 LOC100129534 KLC4 METTL22 NOX1 SNORD18C ZFYVE26 ADCY5 DDX39A SFRP5 PTPN18 ATP6V0E2-AS1 LOC100272217 SLC34A3 RNF185 MSI2 ALDH16A1 GLUD1P3 TELO2 SLC37A4 TMEM129 EPHB3 PDRG1 ZNF785 KATNB1 MFNG REPIN1 NECAB2 500 genes up-regulated by SARS-CoV-2 (2 MOI) in human A549 cells from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/y1oXk9W3L NKX3-1 F2RL1 PPIL3 BIRC3 IL6 CCL2 CCL5 DDX10 VDR CXCL5 ITGB1 TRIB3 PCK2 IL1A ASAP2 DAAM1 IL17RD TIMM9 ANXA3 ATXN3 HLA-B SARS KLF6 SMAD3 NCK1 UGGT2 SERPINE1 FRMD6 MID2 PTX3 INHBE ADAM17 CLIP4 FYN CXCL2 CD8A CSF2 DPH5 STC2 NAP1L1 UBE2E1 ZC3H12C VLDLR CD55 POLI ALDH1A3 ZFAND1 BCL2A1 MT2A CXCL1 SLC16A9 ITGA2 ASS1 EXT1 NT5E RAI14 SYTL2 CA8 OSMR DSG2 TCP11L2 GADD45A RND3 EXPH5 HTRA1 ABCA1 PLEKHG1 ITGAX ITGA5 CLTCL1 SDC4 ALDH1L2 SCARB2 BCAT1 H1F0 LAMC1 IL18 EPHB2 GRB10 KCNMA1 ARNTL2 MTHFD2 AKT3 AKAP12 AZIN1 TUFT1 ZNF185 RUNX2 KLF11 GADD45B AXL CYP4V2 CHURC1 PLAUR CHMP4C LAMB3 SLC38A1 ITPR3 EREG SORCS2 FOXL1 ATF3 GABARAPL1 F2R UPP1 CFB TNFRSF9 CCL20 ULBP1 VAV1 GLIPR1 CRMP1 CTSS PSAT1 LACC1 C3 CXCL3 APOL6 GBP4 C1R CLEC4E NAV3 IFIH1 SOCS3 GBP2 RHCG SAMD9L XDH SLC7A11 SERPINA3 PARP14 FOSL1 PARP11 GFPT2 PLAU SLC6A15 CLIC4 ETS1 CYR61 IER3 MAP1LC3B DUSP1 R3HDM2 TXNIP ICAM1 DTX3L EIF2S3 KLHL5 PXDC1 GBP3 JUN SEMA3C DRAM1 VEGFA DMKN EIF3E EFEMP1 BTG1 SERPINE2 LIMCH1 PDE5A NR1D2 KLF9 TSC22D3 FHL1 RBMS3 IL3RA FEZ2 FSTL1 PHLDA1 PHLDB2 SAT1 SLC38A2 ARRDC4 KDM6B CREB5 DDIT3 TRAF1 MBP BEST1 AOX1 PPP1R15A CSF1 SYT1 TNFAIP3 SERPINB4 PLA2G4C MAPRE3 MATN3 PPP1R15B LIF DUSP5 TIPARP CHAC1 TAF1D MAFF SNHG1 IL11 PDZK1IP1 MMP10 YPEL5 GJA1 EIF2A SERINC1 ELOVL7 SCG5 BEX2 DHRS2 MXI1 SNHG8 MXD1 ZBTB8A DNAJB9 KLF7 OGT SAMD4A EPB41L4A-AS1 MAP1B RRAGC CREBRF MAP2 FAM129A C15ORF48 KDSR C3ORF52 MOSPD1 ITGAV CD47 SERPINB7 ABL2 RAP1GAP2 BEAN1 EBI3 VRK2 ASNS SLFN5 SMOX IL15 NALCN OLR1 IRAK2 AJUBA CCNB1IP1 CYP1B1 LOC100130691 GOLGA8B ANKRA2 CLGN BMPER IL32 DDX60 MAN2A1 GALNT12 DDX60L UFM1 GBP1 TMEM159 KIF1A GARS LIPH SMURF2 XPOT LAMC2 GFPT1 TM6SF1 FMNL2 RELB NFE2L3 CTNNAL1 PMAIP1 RRAGD C1S SOD2 THAP9-AS1 PARP8 SH3KBP1 OPTN GTPBP2 SRGN EIF1 PRKCH SWT1 CBS PRKAG2 HRH1 PTPRE SESN2 LONRF1 SERPINB8 SEMA7A KIAA1549L COL12A1 SPOCD1 FGF2 LINC00707 CD68 NCOA7 C1QTNF1 MEIOB IFNGR1 CDH2 RTCA UBE2H TNIP1 GK NPC1 CARS IFNGR2 NFKB2 NEDD4 PHGDH CYTH1 TMEM167B CCPG1 PDP1 RIN2 PLEK2 ZCCHC7 CLDN1 ERAP1 USP53 ZNF558 SOCS6 GTPBP10 PTPN2 PTPN12 LOC374443 CDCP1 GREM1 CDH4 SLFNL1-AS1 MARCH4 PODXL KIRREL3 NIPAL4 ALPK1 LBP PXDN ABLIM3 PCDH1 LRIG1 HMGA2 PDGFA ITGA3 OCLN AMPD3 NPHS1 PRKCE CPM TGFA STK38L FOXP1 SALL4 HOMER2 DLG3 RRAS2 PDGFB TMEM168 ZFAS1 TNFRSF10B ATP2A3 DRAM2 FBXO32 TFPI NDUFA4L2 FUT1 FGD4 PLD1 ZNF621 ZNF449 ZNF641 WDR41 CLEC2D MTHFD1L ABCA10 PEAR1 SLC16A4 COL5A1 UGCG TSEN15 CDK7 SUPT3H AKNA OGFRL1 CSGALNACT2 ANTXR2 ARHGEF2 ALKBH8 FLNB GAS5 TMEM87B SEL1L3 SLC4A7 C6ORF48 FGD6 C20ORF194 SPIRE1 ROCK1P1 DLC1 L1CAM TUBE1 KIF21B UHRF1BP1 TTC39B ADM2 SLC25A37 HIVEP1 N4BP3 B4GALNT2 LTBP2 LYPLAL1 ACVR1 NMRK1 HEG1 GUCY2EP CEP120 CCDC50 DUS4L NHLRC3 LRRC8C FADS3 C11ORF54 KCNH1 HOXB9 MSANTD3 FHIT DOCK11 MCTP1 ZNF25 TES FAM228B ECM2 RASGRP2 RSL24D1 UFSP2 KIF5C IGF2BP2 SBF2 CLDND1 THG1L PYROXD1 SLC9A7 ICA1 TRPC1 KIAA0319 ZNF697 ZNF277 CLDN12 NABP1 KDM5B AGTPBP1 NTN4 CEBPG RASGRF2 TMX3 LOC100506801 TMEM67 APBB2 TRIM36 GFRA1 TCEA1 SYNGR3 TOM1L1 SPRN ANK2 GALC NGEF IBTK LOC100268168 TMEM156 ZC3H6 HORMAD1 THEG ZDBF2 THAP6 FAM149B1 C9ORF72 QPCT HSPA13 LOC100506548 ZNF146 SNX24 ZFP90 CHST11 IFRD1 LINC00662 CAPRIN2 ANKRD28 CCBE1 ADPRM DNAH17 COL22A1 PPFIBP1 RAB39B GPD1L JMY CCDC90B CPAMD8 CLMP BTF3L4 500 genes down-regulated by SARS-CoV-2 (2 MOI) in human A549 cells from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/y1oXk9W3L TM4SF20 UHRF1 DGAT1 KPNA2 SLC9A3R1 NUP62 ANKS4B CCND3 CYB5B TMEM97 PDZD3 PRR15L KHK TUBB4B GPAA1 NPTX1 HSP90AA1 HNF4A DNMT1 TST TUBA4A POR USH1C TRIM28 FOXA1 POLA2 PHB WFS1 SLC23A1 HSPA8 CAT THOP1 MUC13 FCGBP SFXN5 SLC25A39 FBXL6 POLRMT GADD45GIP1 FGFR4 ARHGAP18 WDR34 EXOSC4 IFT122 KRT18 NT5DC2 KRT4 GPX2 METTL7B CNN3 C1ORF116 BCAS1 CKS2 PRSS23 AGR2 KRT8 EMP2 TMEM109 SRRT UNC93B1 NACC1 TOMM40 TAOK2 EMC10 PPP6R1 MAP3K11 INF2 CLUH SNRNP70 NCLN PLK1 EXO1 DHCR24 MYBL2 TICRR ZWINT CLSPN TK1 TROAP EZH2 LMNB1 TUBG1 GTSE1 AURKB KIF18B SPR CDCA5 SPAG5 AP2S1 MCM2 KIF2C CDC25A AURKA ESPL1 KIAA0895L RRM2 SHMT1 PAQR4 CDC6 E2F1 BIRC5 ORC1 KIFC1 SAPCD2 GALK1 MCM10 SNAPIN GLDC TPX2 CCNB1 NCAPH CBR1 CDCA3 CDC20 PKMYT1 HJURP MKI67 CDC45 ALDH4A1 KIF20A DTL NCAPG TYMS ZNF574 UPK3B NCALD LLGL2 CHTF18 ZFP36L2 FOXM1 SREBF1 AP1M2 THEM6 TONSL PPP1R16A JUP MROH6 IFFO2 MYH14 SPDEF RHPN1 SLC4A2 CLU SFRP4 AXIN2 PRC1 MAP2K6 BIN1 CBX2 RNF26 NR2F1 EDC4 DACT2 CUEDC1 NBEAL2 PITPNM1 MBOAT7 ERF E2F8 UBE2T MXD3 PASK RAD54L ESCO2 ASF1B KIF22 TCF19 GINS2 CHAF1B FAM83D NCAPD2 SPC24 TACC3 ERCC6L NUSAP1 MCM5 SPC25 H2AFX ARHGEF39 CCNF POLE INCENP GINS1 PHF19 CHAF1A CCNE2 XRCC3 DHFR TIMELESS UNG CACNA1G TCIRG1 CLDN2 DIO2 EPHB6 TTYH3 PFN1 LY6E TUBA1B ATP6V0C BAG1 PEBP1 THRA HMGCS1 TPPP3 NDUFA3 U2AF2 ACAT2 PSMD3 TMEM160 SLC12A2 NDUFB7 LYPLA2 DHX30 CALR MPC2 RNPS1 PIGQ DNAJA1 SELENBP1 FASN MYO18A DBI SCAND1 CACYBP NTRK3 TBX3 SCARA5 VAMP1 RADIL IER5L UBE2S TM4SF4 HAT1 ATP6V0E2 RBM42 MIF CKB ATP6V0D1 SLC25A11 MAGED1 PCNA NOSIP POLR2E AHSA1 MFSD5 CXXC5 GMNN TUBB6 HSPA1A RAB1B SDF2L1 VAV3 RUVBL2 E2F7 TOB1 SRSF2 PRR15 GAS2L1 DOK4 HABP2 ATAD2 FANCG MCM6 PCDH9 DNAAF3 MVD BCL2L12 LRRC14 FEN1 ITGA11 RASD1 WDR90 SSNA1 PACSIN1 ISOC2 ACTN4 HLA-DMB CDKN2C PCSK9 MCM4 FAM111B MCM7 SNRNP25 MAD1L1 ALYREF RFC5 LRRC45 NEB LMNB2 APOBEC3B LIG1 NCAPD3 CDCA7L UCP2 BOP1 MLF2 HNRNPL ETS2 TRIM26 BRI3BP SERPINA6 AMPD2 NRGN PIK3R3 HPDL INSL4 ANAPC2 FADS2 NR4A1 OLFML3 FANCA RHBDL3 HOXB13 CCDC34 HSPA1B SDHA SNRPD3 IDI1 MRPS12 AP1B1 USP5 ALG3 VTN SLC35A4 CHMP1A AURKAIP1 SLC25A10 DBF4B THAP7 DDX54 NUBP2 SUV39H1 IRF2BP1 CPS1 NDOR1 TBL3 RAP1GAP WDR81 ADI1 DGCR6L HOXB6 VPS18 LRP3 AMH SYNM LSS ZNF219 MVK METRN FDXR KLHDC7A PRADC1 MBD3 FASTK DDX39A ALDH16A1 TELO2 EPHB3 KATNB1 REPIN1 CPLX2 PLXND1 KANK2 SMPD4 NOC2L TBCD FDPS HEXIM1 TUBB4A APEX2 SHPK FDFT1 MTUS1 CD320 INHBB EHMT2 DTYMK PGP GPC1 LRRC59 RAB26 SCARA3 EMC6 MPP2 ABCB8 ICMT BAAT ADRA1D MCM3 PIN1 RRP36 THOC3 GTF3C5 PKN3 POLD1 MRPL4 RECQL4 RPUSD1 GEMIN4 IPO4 CENPO MMP15 ENO3 IMP3 RNASEH2C SLBP GINS4 POLR2L PEG10 MFSD3 RBM14 GPS1 KIF12 DHCR7 TMPO-AS1 HS6ST1 NSDHL MMAB JMJD8 PCYT2 SLC22A18AS SLC25A1 NTHL1 EBP GMPPB PIF1 ANKRD54 TMEM201 C21ORF58 MPV17L2 ANXA6 HYAL2 PDK2 CNP PHRF1 RAVER1 TECR INTS5 WRAP53 ZNF703 C1QTNF6 SLC39A3 ZDHHC12 HCFC1 ZNF771 CCDC96 FBXL19 PDE3A ZNF672 CABLES2 CASKIN2 DGCR6 CLEC11A FAM222A C19ORF47 IGFBPL1 CACTIN DISP2 GTF3C1 MGAT5B SNHG10 ZBTB45 ZNF444 SAMD11 BRAT1 KCNK5 NOC4L TAF6L NOL12 HAUS5 RABL6 PDF EFCAB12 RFC3 MYRF TMEM53 RNF40 POP7 CXXC1 INTS1 TMEM104 VASH2 HNF1A-AS1 CPSF1 C1ORF159 AARS2 HSPBP1 ZNF787 RHOT2 FOXRED1 DDX12P WDR62 GPRIN2 NR2F6 SP9 RNF43 ADAT3 RAD9A SLC27A3 500 genes up-regulated by SARS-CoV-2 (2 MOI) in human Calu-3 cells from GSE147507 SARS-CoV-2 infection of human Calu-3 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/YI5MaNr0M NKX3-1 IL1B RSRC2 SEC16B BIRC3 IL6 CCL2 CCL5 VCAM1 EGR1 UBD TMPRSS3 NMI TNF PCK2 DDX58 IL1A CXCL10 MAST4 IFITM1 LYN NEDD9 LAP3 JAK2 KLF6 SMAD3 IFNL3 NFKB1 SERPINE1 OAS1 PTX3 INHBE STAT1 TRIM25 IFITM2 PTPRH EIF2AK2 PLAT APOBEC3G OASL CXCL2 IFNB1 ISG15 NUB1 CSF2 STC2 MX1 MYD88 WFDC5 ZC3H12C NR3C1 LIFR KMO ALDH1A3 MT2A CXCL1 TGFB2 TNFSF10 KRT17 HES1 DUSP16 ZEB2 PARD6B NR4A2 S100P DUOX2 NFAT5 C6ORF132 KIAA1217 PNRC1 RICTOR SERPINB2 GADD45A RND3 ANKRD33B PRDM1 SEMA3A ISG20 ZNF462 ARID5B TNFAIP2 PTGER4 PARP10 THBS1 HBEGF PTK2B TYMP BST2 B3GNT7 SLC15A3 SMAD7 ITGAM FBXO6 NLRP1 SDC4 ALDH1L2 ZBTB43 IFI44 EPSTI1 H1F0 SPRY2 APOL4 BATF2 MTHFD2 RASGEF1B G0S2 PTGS2 LAMA2 GATA3 AKAP12 NUAK1 B4GALT5 CDKN1A TUFT1 BMP2 ZFP36L1 KLF10 GADD45B EDN1 PLAUR FOXO1 BCL9L TFAP2A DSG3 IRF6 SLC7A5 ZNF217 EREG SOX9 NAV2 FGF19 ATF3 JAG1 TNFRSF11B BCL3 FOSL2 HELZ2 NUAK2 RSAD2 OAS3 CD69 IDO1 IRF7 ZBP1 NLRC5 GBP5 TAP1 CCL20 ULBP1 IFIT1 SECTM1 CYP1A1 PSAT1 IFIT3 RTP4 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 GBP4 DHX58 C1R KYNU USP18 CMPK2 IFIT2 IFI16 PTAFR NAV3 HERC6 IFIH1 STAT2 PML PLEKHA4 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L HSH2D PIM1 INHBA RNF213 IFI35 PARP14 FOSL1 TRAFD1 SAMHD1 F3 UBE2L6 TLR3 PLAU UBA7 FST WARS SP110 CSF3 SCN3A RIMKLB IRF2 ETS1 KLF4 ZFP36 CYR61 IER3 IRF1 RASGRP3 DUSP1 TXNIP ICAM1 DTX3L NFKBIA IRF9 PSMB9 GBP3 JUN CTGF VEGFA NR1D2 IFI44L SERPINB9 ARRDC3 ATF4 JDP2 ERRFI1 CCNL1 THEMIS2 PHLDB2 SAT1 GEM RBM11 ARRDC4 KDM6B CREB5 SAMSN1 ZC3H12A LST1 DUSP8 TRAF1 EGR2 NR4A3 EDN2 IFNL1 PPP1R15A CSF1 TRIM22 SERPINA10 B3GNT5 C6ORF58 TNFAIP3 HDAC9 CYTH4 ZNF267 PLA2G4C FILIP1L TP53INP2 GIMAP2 BBC3 AMOTL2 PPP1R15B NEURL3 LIF DUSP5 IRS2 TIPARP CSRNP1 MIR155HG CHAC1 BHLHE40 MAFF NFKBIZ TSC22D2 SERTAD2 ZNFX1 FOXO3 FOSB DEPDC7 PNPT1 AMIGO2 MXD1 DNAJB4 DUSP10 PDE4B ANKRD1 NEAT1 EFNA1 SAMD4A TNFSF15 MAP1B CREBRF ITPKC HIVEP2 C15ORF48 RND1 SERPINB7 SIK1 ABL2 ASNS SLFN5 CASP1 PPM1K IL15RA ZCCHC2 MMP13 TRIM21 TRIM56 ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 MAP3K8 RIPK2 IL15 DDO IKZF3 IRAK2 AJUBA SLC1A4 CYP1B1 CXCL11 GSDMB PER1 IFNL2 LAMP3 DDX60 RNF19B LGALS9 TNFSF13B XRN1 SP100 BCL10 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 ADRB2 SAMD9 GBP1 ST3GAL1 GARS TP53BP2 MB21D2 ETS2 CEACAM1 KLHDC7B HDX RELB RCAN1 ETV7 GMPR NFE2L3 PMAIP1 TICAM1 CX3CL1 SP140L C5ORF56 APOL3 N4BP1 RBMS2 BTN3A1 C1S SOD2 TRIM38 PARP8 IL12A PHACTR4 OPTN CFLAR GTPBP2 RAB8B SERPINB1 LTB RASGRP1 KRT6B DENND3 TRIB1 KIAA0040 BCAR3 BACH2 CLK1 SEMA7A BACH1 KRTAP2-3 CALD1 PLSCR1 NR1D1 HRASLS2 DUOXA2 NCOA7 C1QTNF1 CDC14A CCL22 BDKRB2 RIOK3 APOBEC3F TNIP1 NCF2 BCL2L14 SP8 CARS YARS NFATC2 IFNGR2 PELI1 NFKB2 NEDD4 OTUD1 CYLD KCNJ15 CITED2 BHLHE41 PDP1 ZBTB10 GPCPD1 PPP2R2A MARCH4 DAPP1 GBP1P1 MAP3K13 EPC1 NLRP3 LRP2 FUT3 DUOX1 RREB1 KDM6A DAB2IP CYP3A5 PDGFB PLEKHG7 CHD2 HMGN2P46 TNFRSF10B BCL2L11 FBXO32 CD22 NDUFA4L2 FUT1 FLT3LG CTH SAA4 SDS SYNPO UGCG SOX4 GATA6 LATS2 SPSB1 KRT23 FLNB TBC1D22B CSRNP2 TIAM2 DCP1A FGD6 SRFBP1 C18ORF25 PDZD2 ROCK1P1 DLC1 DEFB4A ZSWIM4 C6ORF223 SKIL C6ORF222 KBTBD2 ARHGEF28 L1CAM BAHCC1 FSTL3 TUBE1 EGOT APOBEC3D PA2G4P4 KIF21B GSE1 CXORF38 UHRF1BP1 TTC39B LRRN3 CLK4 CNKSR3 IFNL4 ADM2 SLC25A37 RAB11FIP1 ZNF385C NRCAM HIVEP1 SYTL3 500 genes down-regulated by SARS-CoV-2 (2 MOI) in human Calu-3 cells from GSE147507 SARS-CoV-2 infection of human Calu-3 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/YI5MaNr0M DCTPP1 TIMM8B UHRF1 MALL CISD3 KPNA2 SLC9A3R1 TINAG MME ANKS4B VIL1 CYB5B TMEM97 MIPEP PKM PRR15L TUBB4B CENPF SIGMAR1 AP2M1 TUBA1A CALM1 PMPCA ANXA13 ISYNA1 TSPAN8 PHB HSPA8 CAT THOP1 IGSF9 FBXO9 MDH1 CLDN10 FGFR4 WDR34 METTL7A IFT122 ASB9 SAC3D1 DHRS1 ENO1 DANCR SDC1 NT5DC2 FAM229B UPK1B TSPAN6 C9ORF116 METTL7B CRYM NDUFB2 HIST1H2BK AGR2 KRT8 EMP2 AADAT TSPAN3 PRPS1 TOMM40 STEAP3 VASH1 EIF3B ORAI2 EFTUD2 EMP3 ACLY NCLN PLK1 AK2 DHCR24 TOP2A TICRR ZWINT TROAP SAP30 MRPL12 LMNB1 GTSE1 CDKN3 UBE2C E2F2 KIF18B SPR SPAG5 ANXA5 BUB1B MCM2 KIF2C AURKA DLGAP5 ESPL1 CAPNS1 RRM2 SHMT1 CDC6 E2F1 BIRC5 ORC1 KIFC1 KIF4A MPND COMMD9 SAPCD2 ROGDI HSD17B10 SNAPIN CDCA2 NETO2 NME1 TPX2 CCNB1 NCAPH CDCA3 CDC20 KIF23 HJURP TRIP13 MKI67 CDC45 KIF20A SCD NCAPG TYMS PDGFD CRIP2 MANF SLC2A8 FOXM1 IMPA2 EPN3 THEM6 CYB561 TONSL PPP1R16A PROM2 HR FZD1 WWOX PRC1 PSRC1 CASR CENPA MXD3 PASK RAD54L FANCI ASF1B KIF22 GINS2 FAM83D NCAPD2 NPBWR1 SPC24 TACC3 MCM5 CENPI SPC25 H2AFX ARHGEF39 CENPM CCNF NCAPG2 SYT12 LRP8 CHAF1A SNCA DHFR IGFBP6 RAMP1 VCAN CLDN2 EPHB6 DDC PFN1 HNRNPM TUBA1B TMA7 PEBP1 THRA TPPP3 SMAD6 HPGD LYZ CTSH ACAT2 RPN1 MYH10 COX8A NDUFS3 EIF5A ARL6IP4 PSMD3 IHH CETN2 NDUFB11 HADH NDUFB7 CCT3 AQP1 MPC2 VDAC3 FASN IVNS1ABP NDUFA4 ANAPC5 DBI PGRMC1 NDUFB10 TMEM147 MIEN1 CACYBP QPCTL TMEM213 OST4 ERI3 TM4SF4 HMGB3 ATP6V0E2 NDUFAB1 CUTA MIF AIFM1 POLD2 DCXR ATP6V0D1 PSMB3 DPP3 AHCY NHP2 LSM7 PIH1D1 PCNA HDAC1 POLR2E WDR54 NDUFA8 WDR83OS AHSA1 PTDSS1 POP5 GMNN HSPE1 HSPA1A SF3B5 MRPL11 C1ORF122 LDHB SDF2L1 SOSTDC1 VAV3 RUVBL2 NUDC SRSF2 ID1 MNS1 HSD17B7 CPNE1 SQLE ID2 CDH6 FANCG MCM6 DNAAF3 MVD TCTEX1D2 BCL2L12 SLIRP SNRNP40 FEN1 ANXA10 WDR90 ELOVL6 DERL3 TNFAIP8L1 GCAT MEDAG RARRES2 FGFR3 CYS1 CDKN2C LMAN2L PCSK9 TESC TRNP1 MCM4 MCM7 FAM149A SNRNP25 ALYREF RFC5 RFC2 IDH2 LRRC45 NEB LMNB2 LIG1 RHNO1 NCAPD3 TMEM237 CAPN8 MLEC KIAA0100 UCP2 NEFL HOGA1 GALM BRI3BP TM7SF2 COX5B UQCR11 HPDL CENPV FADS2 SCGN DPYSL3 CCDC34 HSPA1B PRDX2 PGK1 SKP2 ALG1 SDHA SNRPD3 TIMM21 IDI1 PARP1 CA12 TRIM54 GBA APMAP BDH1 SPP1 COPS6 CLN6 SLC25A10 ARMC6 NUBP2 TRMU HSPB11 TBL3 FBXW9 SGK2 HMG20B FAM173A ADI1 DGCR6L TSTA3 RABEP2 POLE4 LSS MVK AMDHD2 PRADC1 ALDH16A1 TELO2 TMEM129 KATNB1 UROD TBCD SIVA1 FDPS HEXIM1 TCTN3 FDFT1 MCCC1 LRPAP1 CD320 CHDH TEX15 ACACA VWA1 DTYMK LRWD1 PGP POLR2F IGFLR1 PRKDC SLC39A4 SCARA3 KCNK2 CYP51A1 RANBP1 GCSH ICMT GJB1 F12 ACSS2 MCM3 ALDH1A2 PIN1 THOC3 POLD1 RECQL4 HNRNPAB IPO4 CENPO ENDOG TUSC2 CTDSPL ANXA9 BCKDHB FAM81A IMP3 RNASEH2C SLBP CHRNA5 GINS4 BCL7C SRPRB RPGRIP1L C1ORF53 MFSD3 AIF1L CAMKMT IL17RB SFXN2 RBM14 CAPS COMMD4 MIR31HG GPS1 MANEAL KIF12 CSPG5 DHCR7 C7ORF50 OSBPL7 KCNMB4 UBE2E3 MUM1 PXMP2 LAGE3 TMPO-AS1 HS6ST1 PAGR1 MRPL41 NSDHL CHST7 PACSIN3 CENPT CTXN1 DPCD MAPKAPK3 SAMD1 PMVK FAM173B PKDCC MMAB DSEL JMJD8 NRM HES6 PLEKHB1 EIF2B1 PCYT2 SLC22A18AS RERG TMEM141 TRAPPC2L DNLZ SLC25A1 ANAPC15 DECR2 MAOB STXBP6 LOC100294145 AGFG2 NTHL1 MRPL3 GALNT10 EBP POLR3K ZNF580 GAMT THAP11 VPS26B GMPPB SYNGR1 MARC1 MYL6B RIBC2 H2AFV TSPAN12 TMX4 PIF1 RAB36 CHCHD6 ANKRD54 DLEU1 SDR39U1 ZFYVE21 PGAP3 ARHGEF19 TUB TMEM201 RPA1 C21ORF58 ELP6 MPV17L 500 genes up-regulated by MERS-CoV in Calu-3 cells from GSE139516 MERS-CoV infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32223537/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/kKnMFGiOQ PTPN14 ATE1 APC EGR1 NMI STX3 PTPN21 EP300 GOLGA3 DDI2 CUL1 RUNX1 KLF6 SMAD3 ZYG11B CRK TLE1 ARHGEF11 PCNT EGFR MAP3K1 BAG5 NR3C1 USP34 NCOA5 BCL2L2 RASEF MECOM MT2A AK4 ENAH ZNF532 SLC40A1 GULP1 MT-ND1 FDCSP LRIG3 CNN3 PEAK1 FREM2 DSG2 GALNT5 TET2 ADGRL2 GADD45A RND3 INPP4B ZNF507 PRSS23 PLEKHG1 TAB2 PTGER4 THBS1 DHRS7 TGFBI EZH2 SLC16A1 KCTD3 MT1F LHFPL2 PDGFC RMI1 FER1L4 C5ORF30 ARNTL2 ZNF365 MPP6 ARL4C ITGB8 AL365203.2 TCN1 EFNA5 ABCC4 PKD2 TRAK1 PKD1 ABCE1 ASB7 CHURC1 ANXA8L1 GRHL2 ADGRF4 HACD2 LRP6 PORCN SHISA2 EFNB2 UMPS DGCR8 MEF2A CREBBP TAB3 BRPF3 RBM47 KIF20B CYP1A1 LRP8 PALB2 F3 TSC22D1 SNRK DTX3L PTPRB JUN CTGF SPECC1L EFEMP1 PDE5A NR1D2 HIPK3 EPC2 ZMYND11 SP3 CNBP LRRC58 CCNL1 RBM3 NAB1 ZFP91 CCNL2 DDX39B FAM102B ARRDC4 MFHAS1 HDAC9 CDKN2AIP BRD1 PPP1R15B FEM1B TIPARP PAPD7 ZNF367 TSC22D2 SNHG1 SOWAHC MSL2 ASNSD1 L3HYPDH TIPIN MBD4 PCNA SGMS1 AMD1 ACTR10 RFC4 MTERF3 SNX4 PUS7 PNPT1 MAP4K3 USP1 GMNN AMIGO2 PCSK5 MALT1 VAV3 SGMS2 KLF7 C15ORF52 COL7A1 PURB SETD2 MAML1 SCAF8 ATXN1L SRSF6 CDH6 ZBTB2 ABL2 PIGW GSTCD ETV6 RNF139 CYP1B1 C6ORF141 FAM13B LPGAT1 SLC26A2 ZNF623 CIPC AHNAK2 MIR22HG SNHG12 PDPK1 GLIS3 NIPBL PIK3R1 ASH1L POGK YY1 FEM1C COA7 THRAP3 ONECUT2 RFX7 PLK2 MARVELD2 IRS1 CHSY1 FUT4 PIK3AP1 GRIN2A RAP2B SRSF11 SMARCE1 SRSF5 DYRK1A GUCY1A3 PPTC7 PRKAG2 IL1RAP LANCL2 SERPINB8 NT5DC3 DSC2 ROR1 PIK3C2G FGF2 RNF144A ETV3 PTPRR PPP1R8 RIT1 SACM1L THAP12 HHEX EIF2AK4 DPP8 CDK6 PELI1 NR2C2 TGFBRAP1 TRAPPC10 RNF34 RNF115 PPM1A KCNJ15 C6ORF62 MPP3 USP36 ERAP1 RBBP6 DNTTIP2 TXLNG WDR75 CCAR1 WDR43 SOCS6 SLC39A8 SMIM13 MIOS DMPK ARID1B TET3 KCTD20 EPC1 SSH1 DST DHX33 TNFRSF11A ZFHX3 MTUS1 MMP7 GCLC ZBED4 CHDH TRPM7 COL4A3BP SENP1 E2F3 GOLM1 TRIM24 ZNF664 ARHGEF37 ARHGAP32 PROM1 SUZ12 NSD1 TMEM168 CHD2 DYRK2 TARDBP ATMIN DAPK1 SLC30A1 RC3H1 ZNF12 ZNF398 ZKSCAN8 UBR7 GCLM NCOA1 MAP3K2 GPAT3 AFDN NFATC3 MTF1 FAM136A NUP50 ZNF639 MCMBP TOPBP1 LATS2 ZNF24 UBP1 FBXW2 MAP3K21 UGDH MT1G CSGALNACT2 USP42 PCNX2 DDX20 MED1 CSRNP2 ARID2 GAPVD1 WTAP RASAL2 ZBTB39 ZBTB24 MED13L ZNF473 TTPAL GPATCH2L ANKRD40 MID1 CEACAM19 FAM168B KBTBD2 L1CAM IL17RB REV3L TFCP2L1 SSX2IP TLK1 CAPN7 VGLL3 MFAP3 CD109 CCDC14 ARFGEF2 ARHGAP21 GFOD1 HGSNAT LGR4 DNAJC9 FRS2 STAG1 AC245041.2 OSBPL10 ZMIZ1 LINC00511 ICE1 ATRN C11ORF95 ZNF131 DDIAS MKL2 PTPRK PHF20L1 ZCCHC14 ELF1 SLF2 HDDC2 TDG ADNP2 TBC1D4 SERTAD4 IDS ANKRD13C PAXIP1 NECTIN3 TSEN2 ZNF148 SENP2 LIMS1 ZBTB40 TSHZ1 DMXL2 DSTYK MELTF USP6NL KRT7-AS TTC17 EMC3-AS1 CMTR2 PDE10A EPHA3 NCK2 HNRNPDL AFG3L1P CFAP97 CASC19 PAXBP1 LINC01963 ASXL2 LIN54 NCBP3 SNX25 PHLPP2 MED13 FUT9 BTBD3 WDR20 ALS2 BICC1 MRFAP1L1 KLHL23 RASA2 DNAAF2 PM20D2 C1ORF131 MYO5A DIDO1 TRAPPC8 CAMSAP2 TRMT10C RC3H2 OTULIN C3ORF58 RBM15 KAT6A SZT2 PDPR PHACTR2 VEZF1 LEMD3 PDE12 FBXO34 AC138969.2 SPATA13 COMMD2 USP38 ZBTB1 CCDC82 C12ORF49 RBMXL1 SVIL LRRC8B SOCS5 NBPF1 CREBZF CDR2 SDR42E1 RAD54L2 PDZD8 PPFIA1 SNX18 WDR53 CDK13 HIPK1 SACS KIAA0232 ZNF783 TMTC3 NBPF8 STX2 KLHL42 AGAP6 OPHN1 CCDC93 KIAA1549 ADGRA3 PBDC1 GPATCH4 TAF5L FGD5-AS1 CLIP1 MTMR12 RRP15 ZNF275 PDPK2P PCNX4 ZNF7 MAP4K5 TNRC6A CHML INTS7 LNX2 DCLRE1A BTBD7 RAB27B AC015712.2 NORAD PPP4R3A EMB ARPP19 KMT5B SLTM AC073869.1 AC245041.1 SNHG3 LIMK2 PKHD1 CDC42SE2 WAPL DHX32 FAM217B ZSCAN29 500 genes down-regulated by MERS-CoV in Calu-3 cells from GSE139516 MERS-CoV infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32223537/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/kKnMFGiOQ GOT1 MAPK3 GDF15 CAPN5 EIF3F RPL36 SLC45A3 SMOC1 DGAT1 UBXN6 IRF3 HIST1H1C PCK2 SLC9A3R1 TSPO UBC PUSL1 ARRB2 TMPRSS4 YIF1A UBXN1 TMBIM1 PFKL PRR15L NDRG1 HLA-B VILL ECSIT ETV4 HSPB1 BAIAP2L2 TUBA1C TP53 HLA-C NUCB1 TST HLA-A ISYNA1 PTPRH LGALS4 PEPD ELOB AGTRAP TGFB1 PTGES2 TKFC REEP6 NEU1 FAH H2AFJ TRAP1 POLRMT DALRD3 NDUFV1 GSTZ1 RPL15P3 KRT18 AC024293.1 RPL18AP3 NINJ1 AQP5 UPK1B METTL7B RAB25 PITX1 RPS2P46 SLPI LCN2 RPL13AP5 STARD10 RPSAP58 CHCHD10 PNPLA2 TNFAIP2 TMC6 VASP XAB2 RPS6KA1 PNPLA6 FKBP8 GNB2 CD81 CYBA CORO1B SHKBP1 SLC16A3 HK1 ITGA5 SLC1A5 MRPL37 TWF2 CAPG HADHA DDIT4 AP2S1 LGALS1 ATP6V1F NDUFAF3 GALK1 RRAS SMTN NECTIN2 ACO2 DYNLL1 PRELID1 CRIP2 FAM131B TJP3 PBXIP1 TRAPPC9 PLAUR ADAP1 SPINT1 FGFBP1 CBLC SCNN1A PAK4 SEMA4B PPP1R13L CLDN3 EPHB4 EPS8L1 CLU WNT7A MAP2K3 FPGS KRT13 TFE3 BCL3 WDTC1 TNFRSF1A RAC2 C3 NPRL3 CLDN2 UBE2L6 SPAG4 SORD COASY CNN2 LY6E EPAS1 TUBA1B IGFBP4 TGM2 HPCAL1 SIPA1 ICAM1 GSTP1 NDUFA3 PSMB9 CHCHD2 COX7A2L SNX17 MDH2 RPS5 EIF3K VPS28 ATP5D LITAF TUBB NDUFB11 KDELR1 RPL18 RPL35 RPS9 NDUFB7 PEX6 PQBP1 ATP6V0B MRPL28 COX6B1 CTU2 CYP2B6 MKNK2 LRG1 MARCKSL1 MYO18A GUK1 FSCN1 CD151 SCAND1 GPX4 PGLS KIFC3 PPFIA3 QPCTL CITED4 DPM3 UBE2S PDLIM1 PDZK1IP1 TM4SF4 MCRS1 WBP2 CIB1 RBM42 C19ORF70 GPKOW CUTA POLD2 DCXR RNASEH2A CKB PTTG1 ASL ATP6V0D1 SLC25A11 SF3A2 RABAC1 PSMB3 ZNHIT1 C12ORF10 MAGED1 AHCY MRPL2 VPS72 LSM7 PIH1D1 DCTN3 NOSIP WDR54 SSR4 MMS19 ETHE1 SNRPA AKR1B1 TUFM TMSB10 HSPA1A CUEDC2 EMC9 SF3B5 MRPL11 TSEN34 RUVBL2 FKBP4 VPS51 MARK4 CPNE1 LINC00116 MVD TNNT1 NUDCD3 FUOM STAP2 GCAT SLC27A1 TFRC BTBD2 TESC AARS NUDT1 IL32 PNKP IDH2 MICB VAT1 MVB12A TM7SF2 ALDOA SEC61B MSRB1 COPE CLIC1 NDUFB4 MTX1 BLVRB RNH1 PHLDA2 SEMA7A DNM1 SLC6A14 SFTA2 HSPA1B PSMC4 ACOT8 PEF1 STX5 TRAPPC1 ANAPC11 PFDN4 RNF5 TNIP1 SH3BP1 TRADD CARS CXCR4 YARS CLPP NFKB2 MRPS12 TXN2 USP5 NR1H2 AIP UBALD2 PHGDH RNF181 VSIG1 AURKAIP1 C9ORF16 APRT TBC1D17 MPST GTPBP6 MRPL52 NUBP2 C19ORF24 TSPAN1 TBL3 FBXW9 HMG20B BCAT2 GPRC5C ASNA1 C16ORF58 HDAC5 TRAPPC6A FDXR PRADC1 KLC4 G6PD CYSTM1 PLXND1 SKIV2L CYC1 ILVBL NCAPH2 TBCD GMPPA FDPS FAM214B MAF1 ERCC1 UNC45A TRIP10 PRSS8 FDFT1 PLIN3 USF2 SOD3 CD320 CDC34 CDKN2A HID1 PDGFB PTP4A3 ATG7 FIS1 BIK EIF4EBP1 DHPS SIRT2 ERCC2 MPP2 ABTB1 AAAS IL17RC FOXA3 ABCB8 SERPINA4 GJB1 SLC29A4 EDA ACSS2 HAX1 HOXB4 GALNT14 MGMT TIMM50 MRPL4 SHMT2 POC1A MRPS34 AKR7A2 NOP53 GRK6 PRDX6 RHOC PNKD NAPRT ACSF2 MRPL23 NYNRIN ANXA9 RNASEH2C EHD2 POLR2L PFKFB4 NIPSNAP1 ATP5B ZSWIM4 C6ORF223 ADM2 MFSD3 CAPS C7ORF50 MRPL41 NSDHL CHST7 NRM TMEM141 SLC25A1 AGFG2 NTHL1 GAMT CHCHD6 MPV17L2 KIF3C STOML1 FAHD2A PDK2 TECR NOC4L HSPBP1 CDK18 ABHD14B RTL8C ZNF341 TMED1 RPLP0P6 A4GALT STX10 MACROD1 DNAJC4 GRAMD1A TMEM187 RPSAP15 HTRA2 C8ORF82 ALKBH7 NAA38 FAM98C NME4 WDR18 OXLD1 ECI1 CAVIN1 RITA1 NLE1 MAGIX NSMCE1 PRR7 NDUFS8 EEFSEC BOK SPAG7 MOSPD3 SLC50A1 METTL27 NME3 LARGE2 MAP4K2 NTMT1 ZDHHC24 RPL10P16 LHPP VARS2 MLST8 RPUSD3 MRPL55 ASMTL RAB34 CARD19 KIAA1191 PPP1R11 CIB2 UCKL1 RPL9P9 ZMAT5 PDLIM4 DHRS3 RFNG CCDC167 DMAC1 MED16 SNTA1 CCDC61 VGLL1 AC008038.1 LINC01843 TMEM161A SPNS2 LONP1 RPL39L UNC5A GALE UBL7 JPT1 OLFM2 ECH1 EML2 EIF3CL KREMEN1 TIMM17B MRPL21 SLC26A9 DCAF11 IDH3G 500 genes up-regulated by MERS-CoV in Calu-3 cells from GSE139516 MERS-CoV infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32223537/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sek4i8YBK BIRC3 TCF12 ZC3H7A EGR1 HECTD1 PTBP2 STX3 PTPN21 ZZEF1 EP300 GOLGA3 NGDN RUNX1 ZNF274 KLF6 EHBP1 RYBP BRD2 FRMD6 MYCBP2 USP54 FBN2 NOS3 TRIM31 FRMD4B CXCL2 ING3 USP15 MAP3K1 FERMT2 HKDC1 PTK2 MYNN RHBDD3 NR3C1 RASEF SH3D19 TMC5 ENAH ZNF532 RARB TRPS1 DUSP16 GULP1 PARD6B GCNT3 COBLL1 LURAP1L TOX3 RASSF6 HSPB8 ZNF827 FAM214A TET2 GADD45A RND3 EYA1 KIAA1671 ABLIM1 PTPRZ1 ZBTB20 ZNF462 ARID5B NEDD4L TAB2 DENND4B MBD1 SMAD7 ITGAM ELL2 GPNMB MAFG H1F0 CARD6 CDKN2B EPS8 ABCB1 ARL4C ARVCF CRY1 ZNF184 ZFP36L1 RMND5A KLF10 KLF11 TGFBR2 WWC1 ZNF217 NAV2 WDR37 ATF3 MAP3K4 EFNB2 ELF4 OR7E91P BCL3 FOSL2 GTF2IP20 CREBBP BRPF3 PLEKHG3 NLRC5 TNFRSF9 CYP1A1 IFIT2 IFIH1 NFKBIE ADM NFIL3 XDH INHBA TSC22D1 ETS1 KLF4 SNRK IRF1 DUSP1 TXNIP NFKBIA JUN VEGFA RABL2A NR1D2 RNF114 HIPK3 ARRDC3 FNTA ERRFI1 CCNL1 YTHDC1 CSNK1A1 GEM ARRDC4 KDM6B CREB5 ZC3H12A DDIT3 AKAP17A DUSP8 SLC25A25 AOC3 TRAF1 RAB30 HSPA6 PPP1R15A CSF1 KIAA1551 B3GNT5 ZNF436 LONRF3 TNFAIP3 SOCS2 HDAC9 IL23A ZNF35 NTNG2 ZNF267 E2F6 ZNF292 ZNF841 PLA2G4C FILIP1L ZNF554 CDKN2AIP BRD1 NEURL3 TIPARP CSRNP1 TSC22D2 KANSL1 FOXO3 BTAF1 FOSB PPRC1 TTC1 AMD1 DHRS2 MXD1 ZNF317 AFTPH INTS6 ADORA2B DUSP10 PAN2 EFNA1 AOC2 LINC00973 COL7A1 GSPT2 SETD2 HIVEP2 USP43 DENND5A ZNF211 REL ABL2 TRA2B TRIM5 ADPRHL1 PIKFYVE THSD7A FAM171A1 FAM13B DDX60 STX16 BCL10 SPAG9 GLIS3 NIPBL SMURF2 ASH1L FEM1C TP53BP2 MB21D2 FNIP1 RNF145 PPP1R10 RFX7 HPS5 ETS2 PLK2 CDK17 CPEB2 CLUHP3 COG3 GTPBP2 GRIN2A MMD RNF6 DYRK1A LPAR6 ATF7IP PPTC7 HRH1 SESN2 TRIB1 IL1RAP SNHG17 BACH2 CLK1 PIGA DSC2 TNFRSF10D NR1D1 PIK3C2G FGF2 ABCA12 SEMA3B RUBCN SUPT20H RIT1 UBE2J1 RIOK3 CAMSAP1 ITCH TNKS EGLN1 SPEN NEDD4 UBAP1 ZBTB38 CYLD SMURF1 SLC35F5 UVRAG ZNF34 AP5Z1 BHLHE41 USP36 PHC3 HELZ ETAA1 RASSF1 GPCPD1 USP53 CCAR1 ZMYM2 MIOS DMPK TEP1 SYNE1 PPP1R3B TET3 MIER1 RAPGEF1 EPC1 VPS54 DST RAF1 ABLIM3 MBIP IL6R MTUS1 PER2 OSTM1 STK38L ZNF3 SENP1 KDM6A KMT2C JMJD1C ARHGEF37 SHROOM3 SETD5 R3HCC1L CHD2 ARHGEF38 PITPNM2 TNFRSF10B EIF2AK3 ZFAND5 UBR5 CD22 UBR1 SLC30A1 RC3H1 TOGARAM1 ZNF398 ZKSCAN8 ZSCAN25 NRBF2 ZMYM5 TRIP11 ZBTB17 SETX PPP2R5A RNF4 SYNPO GPAT3 AFDN NFATC3 SOX4 REPS1 MTF1 TCEAL1 ZCCHC10 UTP15 PPIL4 PRDM4 NR2F1-AS1 PVT1 GATA6 MAP3K9 H3F3B SYNJ1 CELSR3 KANSL3 PCNX2 ZKSCAN5 DDX20 DPF2 NFRKB YY1AP1 SETDB1 MED1 TANC2 GMEB2 PIP5K1A LYST CSRNP2 C6ORF48 SIK3 QKI RNF146 SH3RF2 ZBTB11 ZBTB48 ZNF16 TIAM2 RNF111 KRT8P12 RHOBTB1 RASAL2 WAC ITSN2 USP31 TNKS2 INO80 FGD6 BRPF1 AEN MED13L LPIN2 ZNF550 CIDECP SPIRE1 KDM2A ZNF473 FNDC3A SMG7 ZNF140 GPATCH2L ANKRD40 MID1 CEACAM19 ELMSAN1 EGOT UHRF1BP1 NRCAM REV3L ZNF395 CAPN7 ZNF608 STON2 DENND4C CCDC50 MSANTD3 ZNF697 CEBPG RASGRF2 IBTK DNAH17 ARFGEF2 FRS2 STAG1 LINC00511 ICE1 ZNF131 PHF20L1 ZCCHC14 ELF1 TDG ANKRD13C SENP2 DMXL2 PDE10A CASC19 ALS2 DIDO1 SZT2 SVIL AGAP6 MAP4K5 TNRC6A INTS7 LNX2 SLTM AC009093.4 C1ORF52 7-MAR ZNF592 ARHGAP12 ALOXE3 PPP1R3F TMEM2 KCMF1 ZNF778 FAM86B3P AC107959.3 SMG1P1 ANKRD10 LINC02577 AC110079.1 GPATCH8 C16ORF72 DNHD1 NAA30 CNST RNF103 PPFIBP2 OR2I1P DENND5B DLG1 SPTY2D1 TRIO PPP4R1L BRF2 RSPRY1 RPRD2 STK36 ZZZ3 ZNF609 DNAJC25 ZSCAN26 ZFR MON2 KMT2E MRNIP RALGAPA1 ZMIZ2 AF279873.2 C2CD3 BAZ2B CTNNA1P1 IGHE LCOR CCDC174 ZNF84 AC027290.2 PDE8A OSER1 DNMBP PHF21A NEK1 MYOM1 CNEP1R1 PCF11 CWC25 PLPP3 LINC00346 500 genes down-regulated by MERS-CoV in Calu-3 cells from GSE139516 MERS-CoV infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32223537/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sek4i8YBK BCL2L1 IGSF8 HSP90AB1 SPTAN1 RPL36 SMOC1 PCK2 SLC9A3R1 TSPO NPC2 RHOA TMUB1 IFITM3 TPM4 YIF1A TMEM97 PFKL COLGALT1 PRR15L ELAVL1 ANXA2 HLA-B VILL TUBB4B HSP90AA1 ANXA11 FAM162A GPX1 H3F3A UBA52 FBL PHB2 TUBA1C CTSD HLA-C NUCB1 TST TUBA4A ISYNA1 B2M SFN LGALS4 PABPC1 ELOB EXOSC5 AGTRAP AAMP APP PPIA CHMP2A PAICS PLP2 H2AFJ ADH5 GADD45GIP1 BPNT1 WDR34 NDUFV1 CPT1A TLCD1 RPL15P3 SDC1 KRT18 RPLP2 NINJ1 RPS11 RPL14 UPK1B FDCSP S100A14 RAB25 H3F3AP4 C6ORF132 WFDC2 RPL24 RPL39P3 CKS2 KRT19 ATOX1 GPRC5A TACSTD2 COX7C RPL19 LCN2 KRT8 RPL7A RPL13AP5 RPL31 EMP2 RPL11 RPS14 SLC25A23 CD24 TAGLN2 TMBIM6 BANF1 STMN1 PRKCSH XAB2 APOL1 FKBP8 SNRPB GNB2 MYADM CD81 QSOX1 CYBA CORO1B LMNA PLOD1 URM1 EFTUD2 TKT TMED9 GRN SNRNP70 LTBR ACLY SYNGR2 TIMP1 DHCR24 TK1 CAPG CCNB2 XXYLT1 UBE2C AURKB HSD17B4 HADHA MGST1 CDK5 ANXA2P2 AP2S1 LGALS1 ARPIN CAPNS1 RRM2 PAQR4 PRDX1 MPDU1 GALK1 HSD17B10 GSTO1 MYDGF GAPDH CLDN7 CBR1 CDCA3 PKMYT1 DYNLL1 PSMB2 TPI1 ALDH4A1 KIF20A CRIP2 TPM2 UPK3B FGFRL1 PLCXD1 KLF16 MAVS MANF SLC2A8 ACTB SPINT2 THEM6 CBLC JUP SEMA4B CLDN3 GIPC1 B3GNT3 EPS8L1 LRP5 CD63 TNFRSF1A MBOAT7 UBE2T MXD3 ASF1B GINS2 NCAPD2 SPC25 RAC2 H2AFX CENPM CCNF COTL1 INCENP PSAT1 SFT2D1 CDT1 C3 DHFR UNG NMRAL1 LGMN CLDN2 LIPG IFI35 CD59 PSME1 DPYSL2 RPL28 LASP1 CNN2 LY6E TUBA1B ACTG1 ATP5G3 RAC1 TGM2 RHOG CAPZB SMAD6 GSTP1 MRFAP1 ITM2B CHCHD2 CTGF RPS19 DMKN MAT2A COX7A2 EIF3I MDH2 ITM2C RPL10 RPS5 CTSH ACAT2 EIF3K RPL4 PRDX5 VPS28 ATP5D C1QBP S100A6 TUBB TAPBP SH3BGRL3 COX4I1 NDUFB11 KDELR1 RPL18 HCFC1R1 CD74 RPL35 RPS9 RPL15 PSMB4 SOD1 TALDO1 ROMO1 CALR PQBP1 MRPL28 FXYD5 CFL1 GPI EDF1 LRG1 GM2A RPS3 MARCKSL1 DBI S100A10 CD151 PGRMC1 NDUFB10 SCAND1 GPX4 CD9 MIEN1 BNIP3L TGFB1I1 FUS QPCTL SEZ6L2 CALB2 TOR4A ANP32A PDZK1IP1 NQO1 ATP6V0E2 CIB1 S100A11 RNASEH2A CKB PTTG1 LSM2 RABAC1 PA2G4 PSMB3 NHP2 PPP1R7 LSM7 TSPAN4 PIH1D1 TIMP2 SSR4 AHSA1 SPCS1 TUBB6 TUFM TMSB10 RPL32 RPL29 SF3B5 MRPL11 TSEN34 RUVBL2 GOT2 GLB1 SRSF2 ID1 VEGFB NARF CSRP1 ATP5G2 TNNT1 CACNG6 STK32C GSDMD TRIM56 PTMS PCSK9 MCM4 MCM7 PNKP IDH2 LIG1 TFPI2 RARRES3 LPCAT1 EMP1 VAT1 CSTB MVB12A BRI3BP TM7SF2 ALDOA RSU1 MYL6 MSRB1 CLIC1 NDUFB4 MTX1 COX5B BLVRB PDXK RNH1 NONO CALM2 CD44 HPDL RARRES1 HSPA1B PGK1 PSMC4 ACOT8 PFDN4 ARF5 CLPP MRPS12 ESD NUDT5 EIF3D NR1H2 UBALD2 DFFA PHGDH TOMM22 GSTK1 MYORG VSIG1 ATP1B3 C9ORF16 APRT CD99 ANXA4 COA3 LPCAT4 MPST MRPL52 ASPHD1 HMG20B ASNA1 TRAPPC6A RNPEPL1 MFSD12 G6PD DBNDD1 CYSTM1 RTN3 PPDPF CYC1 UROD TBCD SIVA1 NASP FDPS GUCD1 MAF1 XRCC6 UNC45A PRSS8 FDFT1 WDR1 FXYD3 VSIR GSR TRPV4 LRWD1 GPC1 SLC19A1 RACK1 EIF4EBP1 DHPS EEF2K ATP13A2 ERCC2 GSTM3 MRPS26 GJB1 PDAP1 RBM38 HNRNPAB CDCA4 PRDX6 TMED3 SELENOW NDUFS5 ECHS1 FAM96B PNKD BCAM DYNLRB1 SLBP EHD2 SLC41A3 KDELR2 F11R POLR2L CDKN2AIPNL DUT SDHC CSN3 NIPSNAP1 EIF3H ATP5B MRPL30 AIF1L CAPS HS6ST1 MRPL41 NSDHL NRM SLC25A1 EBP SYNGR1 HYAL2 TECR ZDHHC12 ABHD14B RTL8C STX10 WDR18 ECI1 NSMCE1 NDUFS8 RPUSD3 DMAC1 UNC5A JPT1 TIMM17B IDH3G 9-SEP APEH DESI1 HPS6 LMF2 C2CD4A NKILA ATP5G1 REX1BD YIF1B PPIL2 PFKP FAM155B METTL26 CLPB TP53I13 PAFAH1B3 TEAD4 SEMA4F CAVIN3 AC092171.2 RFXANK FARSA 500 genes up-regulated by MERS-CoV in Calu-3 cells from GSE122876 MERS-CoV infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/30631056/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/C0IkOsNZH TIMM10B BIRC3 CCL2 EGR1 HECTD1 SQSTM1 UBD STX3 TRIB3 DDX58 GCC1 EP300 GOLGA3 NGDN ZBTB7B DYNC1H1 RUNX1 ZNF274 KLF6 EHBP1 NFKB1 BRD2 FRMD6 VARS HGS NUP214 HERPUD1 USP54 OASL NPLOC4 TRIM31 BRD4 FRMD4B CXCL2 USP21 USP15 EGFR CCDC86 MAP3K1 GSK3B HKDC1 CHD1 MYNN ATXN2 RHBDD3 NR3C1 NUDT6 SF1 ZNF410 SGTA NCOA5 MYO10 RASEF TMC5 CXCL1 HES1 DUSP16 GULP1 PARD6B GCNT3 GADD45A RND3 KIAA1671 ZNF462 NEDD4L TNFAIP2 MBD6 DENND4B THBS1 SLC3A2 HBEGF CAD MBD1 GGA1 RHOB MAPK6 ELL2 MAFG NRIP1 CXCL8 ARL4C TOPORS ZNF184 MYC TUFT1 KLF10 MTOR BCL9L WWC1 TRIM16 KRT80 FAM83G SLC7A5 ZNF217 ATF3 MAP3K4 ELP3 EFNB2 ELF4 UPP1 PREB EDC4 STK40 BCL3 FOSL2 DHX34 CEBPB KMT2B CREBBP NUAK2 FBRS SBNO2 MIDN CFB CCL20 CXCL3 IFIT2 IFIH1 PLEKHA4 NFKBIE TNFRSF12A NFIL3 INHBA FOSL1 PLAU TSC22D1 ETS1 KLF4 ZFP36 CYR61 CYTH3 IER3 SNRK IRF1 DUSP1 TXNIP ICAM1 NFKBIA IRF9 JUN VEGFA RNF114 SERPINB9 PISD ARRDC3 RP9 PIM3 DHX30 CCNL1 DNAJB1 FNDC3B NRP1 YTHDC1 GEM ARRDC4 KDM6B CREB5 ZC3H12A DDIT3 AKAP17A DUSP8 SLC25A25 PPP1R15A KIAA1551 B3GNT5 ZSCAN9 LONRF3 VCPKMT TNFAIP3 SOCS2 HDAC9 ZNF35 E2F6 ZNF292 ZNF841 CDKN2AIP AMOTL2 BRD1 PPP1R15B NEURL3 LIF TIPARP CSRNP1 MAFF NFKBIZ TSC22D2 ZNFX1 KANSL1 FOXO3 SLC25A33 PPRC1 MSL2 BCOR POLR3C AMD1 PITPNB GEMIN5 ZNF317 INTS6 ODC1 DNAJB9 ADORA2B FXR2 DUSP10 ANKRD1 EFNA1 SRXN1 GSPT2 SETD2 ITPKC RNF25 SCAF8 HIVEP2 YTHDF2 NECAP1 MUL1 MAP3K14 ABL2 TRA2B ZC3HAV1 IRAK2 AJUBA AARS IL32 FAM13B SMG1 STX16 CHD4 TAF3 GLIS3 ASH1L TP53BP2 SH3BP4 MB21D2 PPP1R10 SDAD1 NAA25 RFX7 SRRM2 ETS2 PLK2 FBXW11 RELB RCAN1 ARL5B N4BP1 COG3 GTPBP2 SON DYRK1A RCOR3 ATF7IP PPTC7 HRH1 PDLIM2 SESN2 TRIB1 RBM12 IL1RAP CLK1 FHL2 GRPEL2 SLC25A32 SEMA7A TNFRSF10D NR1D1 FGF2 NCOA7 POLR1A PTPN1 PLAGL2 SUPT20H ITCH TNKS SPEN XBP1 OTUB2 NFKB2 NEDD4 UBAP1 PRKAB1 FAF2 ZBTB38 SEC16A TRAF2 SMURF1 AKIRIN1 AKIRIN2 URGCP PARP6 USP36 RASSF1 AHCTF1 RBBP6 TXLNG CCAR1 WDR43 RIOK1 HMGXB3 ARFGAP2 PDRG1 STRN4 TANC1 E2F4 RRP12 EPC1 SRCAP C19ORF48 MICAL3 MFN2 NISCH ABLIM3 EDC3 TXNDC11 PEX5 ANKRD17 POLR3A RNF216 TRPM7 STK38L ZNF3 CHD8 SRA1 KMT2C JMJD1C MAST2 NSD1 BHLHA15 SETD5 CHD2 TNFRSF10B EIF2AK3 PHF23 UBR4 SLC30A1 RBAK ZNF227 ZNF398 NRBF2 SHOC2 ZBTB17 SETX GOLGA5 CIAPIN1 RNF4 GPAT3 UGCG MCPH1 REPS1 BIRC6 MTF1 SART3 WDR3 QTRT2 UTP15 PRDM4 RPP14 PELP1 DHX37 GRWD1 RRP1B LATS1 GATA6 MAP3K9 CDK12 ZNF746 MAP2K7 ARHGEF2 OSBP KANSL3 POGZ EIF4ENIF1 KLHL18 NOP2 ATXN2L FAM179B DDX20 ZC3H4 SCAF4 DPF2 NFRKB KCTD5 YY1AP1 THAP1 TXNL4B SETDB1 FAM208B MED1 GMEB2 PIP5K1A C6ORF48 SPATA2 QKI ZNF335 GGA3 CBLL1 RNF146 CNOT4 SH3RF2 NOL6 SRPRB ZBTB11 WTAP ZBTB48 ZNF16 ARID3B SEC24D C1ORF109 RNF111 RASAL2 WAC NFX1 DDX24 INO80 FGD6 BRPF1 AEN BICD2 MED13L SFMBT1 NFXL1 ZNF550 SPIRE1 KDM2A ZNF473 ABTB2 FNDC3A SMG7 FEM1A GPATCH2L ANKRD40 TADA2B MOK ELMSAN1 GSE1 TRIM47 TROVE2 MSANTD3 NABP1 CEBPG GTF3C1 ICE1 ZNF131 TDG RASA2 SVIL CDR2 MAP4K5 NTMT1 ZNF592 ARHGAP12 GPATCH8 C16ORF72 SPTY2D1 BRF2 RSPRY1 ZZZ3 ZNF609 ZFR KMT2E ZMIZ2 CCDC174 PCF11 CWC25 NOCT SETD1A SLC35F6 CREB3L2 MAK16 PIP4K2A GON4L STRN3 FBXO38 ARMCX5 TJAP1 AP3D1 CCDC71 SUGP2 C11ORF24 HGH1 POLR3D C5ORF45 PSPC1 INTS12 ZNF75A ZSCAN21 PRKRIP1 FOXN2 SMYD5 RBM10 C11ORF68 FAM86B1 ZNF239 TMEM265 ZNF598 RBM5 UBE2O NMD3 BRAP RPF2 500 genes down-regulated by MERS-CoV in Calu-3 cells from GSE122876 MERS-CoV infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/30631056/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/C0IkOsNZH SUMO2 CTSL MALL YWHAQ NMI SLC1A1 SLC9A3R1 TSPO NPC2 RHOA TPM4 ATP6AP2 TMEM97 PRR15L ANXA2 NDRG1 HLA-B TUBB4B CENPF NCL HSP90AA1 FAM162A H3F3A TUBA1C TP53 HLA-C PLOD2 HLA-A SAP18 B2M TSPAN8 PRIM1 SFN CAT APP PPIA PAICS PLP2 GLO1 C1D HIBCH ADH5 BPNT1 UFC1 PTTG1IP NDUFB6 CPT1A ENY2 CAV1 RNF128 VKORC1 NDUFA10 TERF1 KRT18 RPL14 RPS24 UPK1B S100P GPX2 TSPAN6 FDCSP S100A14 RAB25 SPAG16 OSMR GALNT3 RPL30 COX6A1 CKS2 KRT19 SLPI RPL39 GPRC5A TACSTD2 COX7C KIAA1143 LCN2 RPL7A RPL31 EMP2 RPL11 SLC25A23 GABRP CD24 TMBIM6 STMN1 APOL1 MYADM CYBA CORO1B GRN TIMP1 NDUFB5 DHCR24 TOP2A CCNA2 SAP30 CAPG CCNB2 GTSE1 CDKN3 UBE2C CREG1 AURKB HSD17B4 HADHA NEK2 MGST1 NUF2 SEC11A HMMR AP2S1 LGALS1 HADHB AURKA DLGAP5 RRM2 CDK1 BLVRA KIFC1 PRDX1 CCT8 GAPDH PRR11 LTA4H CLTA HEXB CEP55 IDH1 CDCA3 DYNLL1 CENPU PSMB2 PRDX3 LIPA CDC45 KIF20A TYMS TPM2 MLF1 AKR1C3 IGFBP3 HINT1 IGBP1 APLP2 CDH1 B4GALT4 ACTB SPINT2 SPINT1 FGFBP1 JUP SEMA4B CLU ODAM SHISA2 CD63 DDR1 CENPK UBE2T ASF1B CHEK1 SPC25 HMGB2 NDC80 INCENP KIAA0101 PSAT1 SFT2D1 DHFR CLDN2 SERPINA3 CD59 SORD PSME1 FTH1 DPYSL2 UQCRB PTGES3 LASP1 TNNC1 TUBA1B ACTG1 AKR1A1 HMGN1 MYL12B RAC1 TGM2 ELOVL5 PEBP1 THRA GSTP1 MRFAP1 ITM2B CHCHD2 SH3BGRL CTGF FABP5 NPNT RBBP7 ITM2C C14ORF166 LYZ RPS5 RPS21 CTSH GDI2 ACAT2 EIF3K COX8A ARPC3 PFDN6 LAPTM4A S100A6 TUBB SH3BGRL3 ATP5H EID1 NDUFB3 NDUFB11 SHFM1 BNIP3 RPL18 BRK1 PTGR1 CD74 SRP14 DYNLT3 IFI30 SOD1 TALDO1 ROMO1 KLHDC3 HN1 SMIM22 COX6B1 NDUFA1 RAB11A DNAJA1 DSTN SERPINB6 GNS LXN SRSF3 CETN3 SUB1 VBP1 MARCKSL1 NDUFC2 DBI RPS27L VCL OAT S100A10 PGRMC1 HIGD2A S100A13 CACYBP DAD1 BNIP3L CBX3 TMEM14B HMGN5 FUS SEZ6L2 STC1 CALB2 ANP32A UBE2A HAT1 HMGB3 NQO1 CIB1 CRYZ MIF RNASEH2A PTTG1 PARK7 MRPL13 SRP9 ZNHIT1 GPR160 DYNLT1 COPS5 NHP2 TMEM230 ANP32E TIMP2 LMAN1 MSH2 PAM NUP37 AHSA1 SYPL1 TNFRSF21 APEX1 FAM107B NIT2 PDCD10 LACTB2 SLC39A10 SPCS1 TMPO UQCRH UXT DCTN6 ITGB3BP TMEM50A MPLKIP TMSB10 HSPE1 EBPL SNRPE RPL32 MRPL11 LRP11 LDHB HSD17B11 SKA2 MRPS6 GLB1 SRSF2 AKR1B10 SRI PRR15 MSMO1 ATP5E RPA3 ATP5G2 ANXA10 PTMS PCSK9 TESC PTGR2 PRSS1 RUSC1-AS1 FAM111B PRTFDC1 RFC2 IDH2 PRPS2 TFPI2 PCYOX1 GINM1 EMP1 VAT1 ANP32B CSTB ERAP2 CA9 PYGL RSU1 CTSA CNPY3 ALDH2 CLIC1 NDUFB4 COX5B BLVRB COX6C NONO CALM2 CD44 ITGB6 RARRES1 CCDC34 PGK1 SNRPD3 DARS HPRT1 ESD SF3B6 NDUFB1 ZDHHC20 UBALD2 ARPC5 PHGDH FCF1 GSTK1 CALCOCO2 SYAP1 TPM1 VSIG1 ATP1B3 ASAH1 COA4 CAPZA1 BLOC1S1 ACAT1 CD99 ANXA4 COA3 MANSC1 MRPL52 STRA13 CLDN1 DPM1 TMEM123 P4HA1 THOC7 ADI1 ASNA1 G6PD CYSTM1 RTN3 NDUFA11 NASP FDPS XRCC6 PRSS8 MMP7 PRSS12 FXYD3 PROM1 P4HA2 GSR RACK1 FIS1 DHPS TFPI CYP51A1 GJB1 FUBP1 PRDX6 CRTAP RNASEK DSE COX7B NDUFS5 ECHS1 MGST3 HNMT SMC1A BRCC3 CEBPZOS DYNLRB1 IMP3 ADGRF1 SLBP IKBIP NUDT21 EHD2 SLC39A6 METAP2 SLC41A3 ALDH7A1 F11R POLR2L CDKN2AIPNL HACD3 DUT SEL1L3 HSD17B12 OAZ2 SDHC CSN3 SSBP1 CHCHD3 NIPSNAP1 MAGED2 OCIAD1 EIF3H ATP5B MRPL30 GBAS CAPS NRM TMEM141 EBP H2AFV EIF4EBP2 ZDHHC12 ABHD14B NSMCE1 SPAG7 VGLL1 IDH3G PFKP PAFAH1B3 GOLIM4 DDTL SNRPF SNRPD1 ATPIF1 C17ORF49 ATP5A1 DYNC2LI1 C14ORF2 TOMM6 PHYH MYCBP ERGIC3 KYAT3 HSDL2 NSA2 SLC20A2 KIAA0754 BCKDHA FAM166A LSM5 500 genes up-regulated by SARS-CoV-1 in Calu-3 cells from GSE148729 SARS-CoV-1 infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/hzVYE4uGL PTPN14 IL1B IL6 ATP13A3 COL6A1 TMEM65 IFITM3 TLR4 FURIN NEDD9 BRAF RUNX1 PMEPA1 KLF6 XIAP USP2 FRMD6 PLCB3 ELK4 EGFR CSF2 PLEC ZC3H12C ARHGEF12 FN3K MCL1 RASEF PCLO ITGA2 POU5F2 KCTD1 FRK AC138393.1 CEP170P1 RAI14 NFAT5 LINC00342 TEAD1 OSMR USF3 KIAA1217 PAWR MARCKS ZNF460 FAM214A MALAT1 RGL1 EYA4 ABCA1 PLEKHG1 CEP170 ZBTB20 ZNF462 MDM2 TNFAIP2 PTGER4 ZNF316 THBS1 PCNX3 TBC1D2B MYADM KHNYN LRP1 EHBP1L1 SMAD7 RHOB ABHD2 C5 EPHB2 GRB10 ABCD1 LRFN3 RNF165 MGAT4A KLF3-AS1 COL18A1 AC016831.1 AKAP12 NUAK1 FAM83H CDKN1A TUFT1 ZFP36L1 TRAM2 PIK3CA EDN1 AGRN TMEM184A CEP170B FAM83F SLC7A1 WNT7A SOX9 NAV2 WNT2B DDHD1 JAG1 MAFK FZD7 NOTCH2 ZNF865 KIF13B MIDN TNRC18 CD274 CCR1 SOCS3 INHBA ANGPTL4 LRAT ETS1 BMPR2 AKAP2 IER3 JUNB JUN ADAMTS15 LBH FNDC3B FASN HPS4 KIFC3 ASXL3 B3GNT5 ZSCAN9 TNFAIP3 NAPSA INSR VASN LIF FEM1B BHLHE40 TSC22D2 PFKFB3 PPP3CA SEC24B AMIGO2 ARHGEF18 PTBP3 ZMAT3 KLF7 ANKRD1 NEAT1 COL7A1 SAMD4A MAP1B TBL1XR1 PURB MAML1 HIVEP2 CDH6 ITGAV RASSF10 PCED1B ETV6 RBM43 IRAK2 GPRASP1 LINC00472 GSDMB TSTD2 PER1 ZNF566 SLC26A2 NHS AHNAK2 TULP4 SMIM10 IGF1R ONECUT2 PAXBP1-AS1 CDKN1B NAV1 ZNF70 CDON NBPF10 PTPRE TRIB1 SEMA7A CTNND2 ITGB6 ADAM19 TBX18 APBB1IP DIO3OS GNA12 IFNAR2 AGO2 CDK6 NFATC2 NR2C2 CYTH1 CCDC92 KCNJ15 BHLHE41 DIP2A GPCPD1 USP53 CATSPER2P1 TMCC1 KCNC4 TEP1 PLCXD2 PPP1R3B CHST3 PHLDB1 TET3 TLE4 STK24 ATP6V0A1 ELK3 VPS13D SSH1 DST NES SPG7 HMGA2 TRIM13 PURA CCN2 GRK5 SLC5A3 IGF2R MTHFR SYDE2 KLF8 SUFU MRTFA LPP ADGRF2 KMT2C ZBTB4 SIPA1L3 KRAS FERMT1 CBL PDGFB CCNG2 PLEKHA8 ANKAR TTC26 ABCA3 UBR4 UBR1 RC3H1 RBAK ZNF449 ZNF197 ZKSCAN8 HUWE1 ANKLE2 UBXN7 SETX TTBK2 CRAT MAP3K2 SFPQ SOX4 PIH1D2 DHX37 GATA6 FBXW2 MAP3K10 SUSD6 DIO3 IREB2 DSE OGFRL1 CSGALNACT2 FLNB UBASH3B GPC4 CELSR3 ZC3H4 ZNF764 MTMR9 MED26 QKI SH3RF2 GAPVD1 TIAM2 RUSC2 RASAL2 ITSN2 FGD6 ZBTB24 ABTB2 SKIL FSTL3 SLC25A37 HIVEP1 MICAL2 LTBP2 MYSM1 DIP2B ACVR1 PGAP1 ANKRD50 VANGL2 VGLL3 MFAP3 DUS4L SBF2 ZNF697 KDM5B CAPRIN2 COL22A1 FBXL19 CASKIN2 ZBTB45 INTS1 VASH2 GFOD1 C11ORF95 ELF1 SERTAD4 USP6NL RASA2 SVIL SACS NORAD AC245041.1 A4GALT PDLIM4 TRIO PPP4R1L MRNIP LCOR DNMBP NKILA AC017074.1 HSPG2 AC020916.1 PHF13 KCNQ3 AC118344.1 CACNG8 AP000577.2 VPS13A ZBTB3 EVI5 NCKAP5L AP001486.2 AC104162.2 AC048341.1 AC005261.2 GOPC AL021578.1 ADAMTSL4-AS1 AL353625.1 AC087501.4 AC037198.1 ZXDB RPAP1 AC087190.3 TUG1 AC009163.4 PANK3 TMED7 KLHL28 AL138756.1 ZSCAN20 PRKAR2A-AS1 LINC01176 MFSD4B TUT4 AL596244.1 Z68871.1 MORC2 RGMB AC092747.4 PDIK1L AP001767.4 AL591848.4 C2ORF69 SLC41A1 SH3BP5-AS1 AL118505.1 ZBTB7A H1FX-AS1 HIF1AN AC120114.3 LYPLA1P3 ATP6AP1L AL365436.2 AC002480.2 SLC2A3P1 SPACA6 RPS15AP10 ZNF248 LINC02331 AC007406.5 TBC1D32 AC091144.2 ZNF815P SOS1 ZNF654 MICU3 LINC02062 MIR193BHG AL356124.2 DIRAS2 SLC25A30 AP000347.1 MCM3AP PIAS2 GPR135 MTX3 REST AC135050.6 GHRLOS FRA10AC1 AC010680.2 DTWD2 AC096887.2 MAGI1-IT1 AC125257.1 EMSY AL136164.3 STXBP5 PADI1 AC007191.1 KRT18P11 SNAPC3 LINC00205 HECW2 PALLD LINC02551 LRP5L TRHDE-AS1 TTLL7 AC092835.1 OTUD4 DOCK5 AP000769.5 TPM3P9 RAPGEF6 SCAI AC093010.3 EHMT2-AS1 RECQL5 RAI1 AHDC1 GABPB1-AS1 AL353795.3 AC067838.1 AC138150.1 BRWD1 MIR1244-2 ZNF106 AC073109.1 DNAH10OS TP73-AS1 TAF1A-AS1 ZNF594 AC010186.2 PRKAB2 SNX33 AL451064.2 ZNF222 BICRA FAM20B LPAR5 CRYZL2P HNRNPA3 GPR161 TLCD4 AC111000.2 PCDHGB5 LTO1 TENT4B AC092614.1 AC092153.1 AL445686.1 AC016831.6 HNRNPA1P33 AC010198.2 PWWP3B KLHL29 CAPN15 PCDHGB9P FAM199X AC103746.1 SOS2 AC004918.5 IRGQ ZNF516 ZNF585A C14ORF28 FBXL21P GJC1 AC000123.3 PRRG4 SPRING1 USP32P1 CDK14 ZNF805 NAA16 AC005839.1 498 genes down-regulated by SARS-CoV-1 in Calu-3 cells from GSE148729 SARS-CoV-1 infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/hzVYE4uGL UBB DCTPP1 UBL5 EEF1A1 FCGRT GHITM SPINK1 RPL36 DDX58 NPC2 ANXA3 YIF1A RBX1 ANXA2 TUBB4B GRPEL1 TUBA1A GPX1 UBA52 OAS1 NUTF2 POGLUT2 SDF2 B2M TSPAN8 FAU HSBP1 ITM2A PHB ELOB KRT20 RNLS ARL14 MX1 MDH1 CLDN10 ADH5 EXOSC4 ADK PSMA2 OCIAD2 RPS26 DANCR RPS16 RPS3AP6 RPL35A AC034236.1 EEF1A1P6 UQCR10 RGS2 RPL10AP6 ARL3 RPS11 RN7SL1 RPL27 AC099336.2 RPL41 GPX2 MT1E METTL7B RPS8 RPL38 RPL7AP6 RPS3A AC116533.1 SCEL RN7SL3 SERPINB2 RPL13P12 RPL30 APOBEC3A RPL23 RPL13A COX6A1 RPL24 RPS25 TSTD1 RPS15 SLPI RPS13 COX7C AGR2 RPS29 CFAP53 COPS9 RPL31 RPSAP58 RPS23P8 RPS14 RPS7 RPL7 VTCN1 TMBIM6 STMN1 CPVL GLMP P2RX4 TK1 ATP5MC3 CCNB2 AURKB MGST1 CDK5 ANXA2P2 MT1F DERA ATP6V1F KNSTRN RNASE1 CDC6 BLVRA RPL26L1 NME1 CCNB1 DYNLL1 ATP5F1C TPI1 KIF20A CD163L1 PSMB7 AC012085.1 RN7SL4P TCN1 SLC2A6 CKS1B GAD1 KRT14 NUCB2 CD63 UBE2T CFB MTFR2 GINS2 IFIT1 ARHGDIB ARHGEF39 PSAT1 CDT1 IFIT2 RAMP1 HSH2D PSME2 RPS28 TMA7 SDHB TXN ID3 ANAPC13 RPS23 CHCHD2 CA2 RPS19 CYB5A SNX17 SNRPD2 RPS5 RPS21 CTSH RPS10 NDUFA13 RPL4 PSMB6 PSMC2 PFDN6 LAPTM4A ABRACL RPL18 BRK1 RPL35 OAZ1 NDUFB7 RPL18A NDUFA2 SOD1 EMC3 ROMO1 PSAP PQBP1 SMIM22 COX6B1 PSMA6 NDUFA6 ANXA1 UQCRHL HLA-DMA ELOVL1 NDUFA4 SAT1 NOP10 GTF2B DBI MIEN1 TMEM14B UBE2L3 NDUFS2 ZNHIT3 ATRAID DPM3 SNRPG PDZK1IP1 TM4SF4 HAT1 MRPL24 EMC4 ATP6V1E1 TMEM208 NDUFAB1 MRPL27 CRYZ ARL6IP5 PFDN2 SARNP PTTG1 C12ORF57 UBE2N LAMTOR5 PSMB3 TFPT ORMDL2 CCDC58 C19ORF33 TMEM14A ZNF513 NOP58 UQCRQ PIH1D1 PCNA POLE3 EMG1 BCAS2 WDR54 NDUFA12 RFC4 NELFE POP5 UQCRH MRPL17 GMNN ERH TMSB10 RPL29 CUEDC2 DECR1 SF3B5 GEMIN6 RPL34 MRPL18 ID1 AKR1B10 RNF25 MRPL47 SLIRP VAMP5 SNHG5 BID FAM111B SNRNP25 MRPS11 CT83 IFIT5 PKIB ORC6 ZBED5-AS1 NAPA MDK RPL23A SERF2 CLIC1 COX5B BLVRB UQCR11 SIRT4 SFTA2 PSMC4 TIMM23 EXOSC10 COQ9 PET100 ARL2 TMEM11 STX8 TXN2 HMOX2 NDUFB1 ARPC5 TAF9 SPP1 RNF181 SUCLG1 ATP5MD ATP5MPL ATP5F1E ADPRS C19ORF53 ATP5F1A CCDC115 COMMD6 ATP5PO ATP5ME THAP7 NUBP2 CHST4 PMF1 BCAT2 DUS3L F8A1 ANKRD22 CYSTM1 PARVB TIMM13 UROD C19ORF48 FDPS PUDP FDFT1 SNX2 LRPAP1 SLC44A4 IFT57 RACK1 MRPL40 FBXO4 GJB1 BRMS1 PSMA5 CDKN2D PIN1 LSM4 TMEM59 TMEM14C SELENOW MT1G NDUFS5 MGST3 HNMT NANS KRT23 TIMMDC1 CHRNA5 RPL23AP42 KRT223P IL17RB COMMD4 DHCR7 LAGE3 DPCD PLEKHB1 SLC22A18AS MRPS21 RSL24D1 KIF5C HYAL2 HDDC2 RPLP0P6 MRPL55 ECH1 AC027309.2 BOLA2-SMG1P6 H4C12 AL009179.1 H2AC12 AL031729.1 C8ORF31 LINP1 H2AC11 AC010323.1 MICOS13 ADM5 MAPRE2 SNORA47 AL392086.2 EEF1E1 AC106795.1 TCHP H4C9 AC246787.1 RN7SL832P NDUFC2-KCTD14 AL121594.1 ERG28 SNORA84 H2AC6 NEDD8-MDP1 H2BC13 AL355075.4 PSMC1P1 ELOA-AS1 FRS3 SNORA9 H3C10 MRPS14 RPS10P3 CD24P4 MRPL57 CIDECP1 H2BC10 CENPX HSP90AA2P AC005258.1 AL645922.1 LSM3 SMIM26 AC008966.1 H2BC11 CHCHD2P2 H1-2 AC010132.3 SUMO1P3 AC011448.1 FAM104B TMEM134 SMYD2 ZCCHC17 NOP16 H2AC7 AL035458.2 AC073896.1 RPL4P4 AC092718.4 H3C8 PLAAT4 IDNK H4C11 CYP51A1P1 H2BC4 IL1RL2 CFAP20 H2AC8 BUD23 MRPL43 H4-16 H3C4 H2BC6 H2BC8 BEX3 AL158801.6 LIN52 CBY1 SNORA74A ALG1L H3C7 RN7SL2 MIR3651 H4C4 PRRX1 MED19 H2BC18 H3P6 TPI1P1 KRT8P10 UQCC2 TMSB4XP8 NIFK-AS1 COMMD5 LOC101927572 ADH5P4 H2AC17 H3C13 EXOSC9 RANP1 SCARNA13 RIPOR3 H2AC14 AL050309.1 COX7CP1 H3C12 AC108673.3 AP000311.1 PAOX MRM3 H2BC7 AC097625.2 TMCO1 TMEM9 MIA H1-3 AC010342.1 AC073548.1 STK32A-AS1 FANCE MRPL50 RPP25 AL161756.1 FAM53A H2AC21 H4C3 AL031777.2 WBP1 H1-5 SCARNA7 H4C2 H1-4 ATPAF2 RPPH1 EEF1B2P3 H1-1 ATP6V1E2 AC005833.1 500 genes up-regulated by SARS-CoV-1 in Calu-3 cells from GSE148729 SARS-CoV-1 infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/6phIHWJaQ ANO9 NKX3-1 CEP350 RSRC2 BIRC3 IL6 GDF15 CCL2 CCL5 EGR1 SQSTM1 VDR NMI TNF DDX58 IL1A CXCL10 IFITM3 CYP2J2 IFITM1 HLA-B LAP3 ZNF274 JAK2 KLF6 IFNL3 NFKB1 BRD2 SNIP1 OAS1 PTX3 STAT1 TRIM25 IFITM2 AASS MYCBP2 EIF2AK2 OASL MOV10 CXCL2 IFNB1 ISG15 AKAP8L NUB1 CXCL9 ARL14 CSF2 MX1 MYD88 WFDC5 OVOL1 ZC3H12C NR3C1 KMO PCLO MT2A CXCL1 TNFSF10 IFI27 DUSP16 ZEB2 NFAT5 SNORD17 CFH RICTOR RN7SL3 HSPB8 SNORA73B FAM214A TET2 ANKRD33B SEMA3A ISG20 ZBTB20 ZNF462 CMTR1 TNFAIP2 PTGER4 PIEZO1 KSR1 PARP10 SH3TC1 APOL1 MBD1 BST2 SLC15A3 SMAD7 ITGAM APOL2 HLA-E IFI44 AC007952.4 MAFG SLC1A3 Z93241.1 EPSTI1 APOL4 BATF2 SNORD3C RASGEF1B LINC00944 CXCL8 IKZF2 RNU4-1 PTGS2 SCARNA5 SLC2A6 B4GALT5 BMP2 KLF10 PLAUR FOXO1 ZNF217 NAV2 ATF3 FZD4 SLC12A7 HELZ2 NUAK2 PLEKHG3 OGFR SBNO2 RSAD2 OAS3 IDO1 IL10RA IRF7 CFB ZBP1 NLRC5 GBP5 TNFRSF9 TAP1 CCL20 IFIT1 CYP1A1 IFIT3 RTP4 HLA-F OAS2 C3 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 GBP4 DHX58 USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 STAT2 PML PLEKHA4 NFKBIE ADAR NAMPT GBP2 NT5C3A PARP9 PARP12 SAMD9L HSH2D ADM PIM1 INHBA RNF213 IFI35 PARP14 TRAFD1 SAMHD1 UBE2L6 TLR3 PLAU UBA7 FST SP110 SCN3A AHR KLF4 ZFP36 IER2 FOS IRF1 RASGRP3 DUSP1 TXNIP ICAM1 DTX3L NFKBIA IRF9 PSMB9 GBP3 JUN IFI44L SERPINB9 ARRDC3 PIM3 ERRFI1 CCNL1 THEMIS2 SAT1 GEM ARRDC4 KDM6B CREB5 NPFFR2 ZC3H12A DDIT3 DUSP8 SLC25A25 TRAF1 EGR2 IFNL1 HSPA6 PPP1R15A CSF1 TRIM22 B3GNT5 ZNF436 TNFAIP3 HDAC9 ZNF267 ZNF292 FILIP1L BBC3 AMOTL2 PPP1R15B NEURL3 LIF FLRT3 DUSP5 IER5 TIPARP CSRNP1 MIR155HG MAFF NFKBIZ TSC22D2 ZNFX1 FOSB SH2B3 PNPT1 MAP4K3 DHRS2 CCDC117 MXD1 DNAJB4 GPBP1 DNAJA4 E2F7 DUSP10 NEAT1 EFNA1 COL7A1 SAMD4A TNFSF15 ITPKC HIVEP2 RND1 C3ORF52 REL ABL2 TAP2 SLFN5 PPM1K IL15RA ZCCHC2 TRIM21 USP25 TRIM56 ZC3HAV1 TRIM5 TDRD7 TRIM14 MAP3K8 RIPK2 ACTN2 IKZF3 IRAK2 PRKD2 CYP1B1 CXCL11 THSD7A STX19 IL32 PER1 IFNL2 LAMP3 DDX60 RNF19B LGALS9 XRN1 SP100 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 ADRB2 SAMD9 GBP1 TP53BP2 MB21D2 FNIP1 ANKRD12 ETS2 CEACAM1 RELB RCAN1 ETV7 GMPR CPEB2 CLUHP3 PMAIP1 TICAM1 OXTR CX3CL1 STYK1 SP140L ACHE APOL3 N4BP1 SMCHD1 WHAMM TMEM62 BTN3A1 HCP5 SOD2 TRIM38 FAS PARP8 OPTN TRIM26 SERPINA6 RASGRP1 GLCCI1 HRH1 SNHG20 BACH2 CLK1 SEMA7A IGF2 ABCA12 NCOA7 HLA-H HLA-J MMD2 RUBCN IKBKE TENT5A TANK PPARGC1A PELI1 NFKB2 NEDD4 STK10 OTUD1 CYLD SMURF1 AP5Z1 EPHA4 USP36 FLCN GPCPD1 CCNT2 TEP1 MEG9 SYNE1 PLK3 RNU12 DAPP1 MAP3K13 SNORA48 EPC1 MICAL3 WDR74 HLA-DOB DUOX1 KDM6A KMT2C JMJD1C COL11A2 SETD5 CHD2 HLA-V TNFRSF10B EIF2AK3 ATG2B UBR1 ZNF627 TOGARAM1 ABCA5 SYNPO AFDN ERN1 PRDM4 COL16A1 TBC1D22B PIP5K1A LYST ZNF335 ARID3B DCP1A MTMR3 ITSN2 INO80 MED13L LPIN2 KDM2A ZNF473 ABTB2 PDZD2 FSTL3 EGOT UHRF1BP1 LRRN3 CLK4 IFNL4 HIVEP1 AFAP1 REV3L ZNF697 RASGRF2 IFRD1 DNAH17 AC107959.3 KMT2E BAZ2B IGHE PLPP3 NOCT RBM5 AL021578.1 AC093010.3 AC073109.1 PLAAT4 SNORA74A AC019117.4 SNORA49 CPEB3 AF117829.1 ARID4B SNORA70 MIR3609 PPP4R4 SCARNA6 RNU2-2P MED12L CFAP54 TLK2 AC124319.3 AC010733.2 AC132217.2 SNORD3D MIR3142HG ARL4A RTL9 ZNF441 SCARNA16 AC105105.4 NBPF26 TGIF2 AL136295.5 SNORD10 RNU4-2 LINC02701 RIPOR2 ZNF433 SHFL AC083837.1 ARL14EPL GRIP2 AL669918.1 CPEB4 WARS1 FRYL DENND4A SNORA57 SNORA73A LCAL1 ARAP2 SNORD13 LINC02068 AC140912.1 SIPA1L2 SNORA68 SNORA63 SNORD3A DCLRE1C AC139491.2 SNORA71A MEG8 499 genes down-regulated by SARS-CoV-1 in Calu-3 cells from GSE148729 SARS-CoV-1 infection of Calu-3 cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/6phIHWJaQ DCTPP1 EEF1A1 TBCA FCGRT YWHAQ SUN2 ATP5MG LMAN2 TSPO RPL13 RBL2 TPM4 PPT1 ATP6AP2 PRR15L ANXA2 NDRG1 ETV1 VILL CENPF PMEPA1 AP2M1 CIT TUBA1A ANXA11 FAM162A PLS1 ANXA13 CTSD TUBA4A TSPAN8 ERBB2 ST6GALNAC1 USH1C LGALS4 HSBP1 ITM2A PLS3 PPIH CAT MDH1 VAMP8 CLDN10 SCP2 UFC1 PTTG1IP METTL7A NDUFV1 NDUFB6 ACO1 IFT122 RPS20 RNF128 ENO1 RPS17 RPS3AP6 SDC1 AK4 NT5DC2 PERP AC024293.1 CFTR AC026403.1 EEF1A1P5 C1ORF21 RPL41 UPK1B SH3BGRL2 TSPAN6 NDUFB2 RPS3A MARCKS PLCE1 STEAP4 RPL30 BCAS1 RPS7P1 RPS25 TSTD1 KRT19 RPS15 AGR2 CHST9 NFIA EMP2 VTCN1 GABRP CD24 TAGLN2 ATP1A1 TMBIM6 STMN1 UQCRC1 GSN FKBP8 PIGK CYBA INF2 CMTM6 ABHD2 PLK1 DHCR24 TOP2A CCNA2 TK1 CCNB2 GTSE1 CDKN3 UBE2C FZD2 NEK2 SPR NUF2 ANXA2P2 KIAA0930 SPAG5 ALCAM AURKA FADS1 SHMT1 BIRC5 KIF4A NIBAN2 COMMD9 SAPCD2 PRR11 LGALS3 NME1 CCNB1 NAGA IDH1 CDCA3 PRDX3 LDHA TPI1 SORT1 KIF20A SCD NCAPG CA11 PDGFD CRIP2 COL18A1 TCN1 PBXIP1 APLP2 THEM6 JUP CLDN3 TPD52L1 HR TMSB4X ODAM CD63 PRC1 BIN1 SLC16A5 ARHGAP11A CENPA IQGAP3 NCAPD2 SPC24 ARHGDIB SPC25 MAD2L1 MOGAT1 DHFR NMRAL1 SLC3A1 CD59 DDC TTYH3 DPYSL2 RPS28 UQCRB TSPAN13 LASP1 YBX1 TMA7 COX17 THRA TXN RPS23 COX7A2L RPL3 CYB5A CST3 COX7A2 ITM2C LYZ RPS21 CTSH ACAT2 MYH10 NDUFA13 PRDX5 S100A6 TMEM160 SLC12A2 CETN2 EID1 NDUFB3 NDUFB11 RPL18 HCFC1R1 VIM OAZ1 NDUFB7 ROMO1 PSAP AQP1 MPC2 COX6B1 NDUFA1 RAB11A NDUFA6 GM2A RPS3 NDUFA4 NUCKS1 DBI SEC61G OAT S100A10 PGRMC1 GPX4 BNIP3L FAM102B CBX3 OLFM4 HMGN5 PAH TP53I11 HOXB8 TMEM213 PLA2R1 MIR210HG TMEM258 ATRAID SNRPG TM4SF4 HMGB3 GYS1 TMEM205 NDUFAB1 CRYZ MIF POLD2 PTTG1 HMGB1 PARK7 YPEL5 MRPL13 SRP9 GPR160 AHCY NHP2 ACTL6A UQCRQ PIH1D1 ANP32E GNG12 POLR2J UQCRH HOXB7 HMGN3 PFN2 SNRPE ETFB LDHB VAV3 TXNDC12 SERINC5 SKA2 ARL6IP1 MNS1 SRI PGM1 MSMO1 TMEM139 CD46 DNAAF3 ANKRD9 RPA3 TNNT1 TFRC FGFR3 CTSV RAB11B CFI MBNL3 IDH2 GALNT12 AHNAK2 NEB LIG1 PRPS2 TFPI2 MLEC CBX5 DNAJC22 REEP4 PRKACB VAT1 BRI3BP TM7SF2 ALDH2 UQCR11 PDXK PDK1 LMCD1 SEC14L2 SCGN ROR1 RARRES1 CCDC34 PRDX2 PGK1 ACP1 PET100 COX11 IDI1 FAIM BSG ROS1 CA12 SC5D GNPNAT1 NUDT5 SELENOF APMAP COPG2 ARPC5 PHGDH COX16 SPP1 PPCS SYAP1 GALNT1 TPM1 ASAH1 AHNAK ATP5PD ATP5F1E C4ORF3 APRT CCDC115 ACAA2 ANXA4 COA3 ATP5ME GGCT NUBP2 LRRC20 TSPAN1 MRPL33 OBSL1 BCAT2 TRAPPC6A ATP9A KLHDC7A KLC4 MSI2 ALDH16A1 G6PD RTN3 UROD FDPS SLC52A3 UNC45A FDFT1 SPOCK2 ACSM3 SEMA4G TEX15 SERPINA5 SLC44A4 HOMER2 SH3GLB2 FXYD3 PROM1 DTYMK NOTCH3 EIF4EBP1 RAB26 STK11 GSTM3 LTBP1 CYP2U1 IMPDH1 ELMOD2 SERPINA4 GPLD1 GJB1 LMO4 PPP2R5D MGMT LSM4 ENDOG TMEM59 COX7B NDUFS5 MGST3 SLC25A20 ACSF2 NYNRIN PALMD ANXA9 FAM81A IKBIP NAALADL2 DARS2 ANAPC16 ALDH7A1 POLR2L HACD3 MSL3 RPGRIP1L AIF1L CAPS KCNMB4 DSEL PLEKHB1 MAOB EBP PGAP3 CARHSP1 PXMP4 CPD GPSM2 LMBRD2 TES PDK2 STX10 CAVIN1 CCDC167 DMAC1 RPL39L ECH1 MYOM1 GOLIM4 LSM5 AC027309.2 H2AC12 H2AC11 NEDD8-MDP1 LSM3 BEX3 NUDT3 PPOX AC068580.4 SDHAF4 AC009779.4 MGAM2 ARSD AC020907.6 SEPTIN9 AC245033.1 AP000350.4 MACROD2 YBX1P10 SVIP PRR34-AS1 CCDC171 QARS1 LINC02532 RASAL1 H2AZ2 AC245033.4 AL450405.1 HMCES PRXL2A TBC1D16 NIPAL3 ZNF428 YBX1P1 AL121753.2 AC010197.2 BAIAP2-DT SGO2 ATL3 SSPN SEPTIN2 DYNC2I2 H2AZ1 LINC01559 SRP9P1 AC243919.1 LNPK IFTAP AC104532.1 CBX6 GPALPP1 RTL8B TMSB4XP6 CNIH4 SYT11 LOC105375224 AC005943.1 499 genes up-regulated by SARS-CoV-2 in Calu-3 cells from GSE148729 SARS-CoV-2 infection of Calu-3 cells Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sKZloen5y NUP210 ATP6AP1 EGR1 MDN1 LARP1 PTPN21 GOLGA3 RASA3 RUNX1 KLF6 FRMD6 NUP98 ZNF318 IFNB1 EGFR PLEC RCOR1 ERC1 ARHGEF12 SIAE MYO10 PCLO ITGA2 KCTD1 RAI14 NFAT5 LINC00342 LURAP1L USF3 KIAA1217 TNS4 QSER1 C1ORF116 MALAT1 EYA4 ZNF462 SYMPK MYO1G MBD6 IL4R GSK3A ZNF316 THBS1 H6PD PCNX3 MYADM KHNYN ACCS CAPNS1 PPARGC1B ARHGAP23 LRFN3 FAM131B AC016831.1 AKAP12 NUAK1 FAM83H CDKN1A TUFT1 CNOT6 ZNF189 TRAM2 EP400 FGFR1 CELSR1 DSP TMEM184A FAM83F FAM83G SLC7A5 ZNF217 ITPR3 LAMA5 IFNE FZD1 WNT4 DMRTA1 PRICKLE1 FZD8 NFIC ATF3 JAG1 HERC2 MAFK DYRK1B DHX34 NBEAL2 AP5B1 CSNK1D EME2 BRPF3 SCAF1 SETD1B MIDN CAMK4 IL18BP MOGAT1 CD274 CTSK HAS3 SOCS3 KCTD19 HAS2 ANGPTL4 ETS1 KLF4 IGFBP4 JUNB JUN ADAMTS15 ITPRIPL2 CAMTA2 ERRFI1 WNK1 FNDC3B FASN MEGF8 AGO4 IFNL1 SLC22A14 TNFAIP3 TMEM150C FUS INSR FOXK1 BCORL1 SKI AMOTL2 LIF CSRNP1 BHLHE40 NFKBIZ SERTAD2 PFKFB3 SEC24B ARHGEF18 KLF7 NEAT1 LENG8 GPR75 COL7A1 MAP1B ZNF618 MAML1 CEMIP DENND5A IL1R1 RAP1GAP2 TATDN2 POLR3H KCNJ11 SOCS7 ETV6 MARS2 TRIM56 NEU3 GPRASP1 ZNF561-AS1 ISL2 IFNL2 ZNF566 DDHD2 SMG1 LONRF2 AHNAK2 ZNF257 NPIPA1 ZNF573 PDPK1 ASH1L IGF1R HSD17B7P2 ETS2 TICAM1 RBMS2 CERK AMPD2 DYSF ROCK1 NAV1 CDON PPTC7 PRKAG2 PTPRE TRIB1 SERPINB8 MBLAC2 SEMA7A KIAA1549L ADAM19 TBX18 ALPK3 DIO3OS GNA12 SEMA4D RUBCN MTR AGO2 SPRY1 ATP2A2 PPP4C SEC16A TRIM11 SMURF1 KCNJ15 DCUN1D2 ZNF324 TSPAN14 USP36 STAG3L1 ZNF587 FLCN HELZ DIP2A CDCP1 HMGXB3 KLHL21 KCNC4 TEP1 PLK3 CHST3 AKAP13 MLXIP ASB1 CRTC1 SSH2 ATP6V0A1 ELK3 SSH1 SLC9A1 NES HIPK2 SPG7 UBE2Q1 CCN2 MTHFR PLXNA1 KCNH8 KMT2A MRTFA ADGRF2 KMT2C ZBTB18 HOMER2 RALGAPA2 FERMT1 CBL ABCC10 PDGFB SETD5 MRTFB NPIPB4 ABCA3 WDFY3 DCAF1 CARD10 MKNK1 HK2 ZNF749 ZNF202 UBR3 HUWE1 GBF1 EYA3 MTF1 DHX37 GEMIN4 GATA6 MAP3K9 MAP3K10 SUSD6 IREB2 ZNF142 OSBP CELSR3 PCNX2 KLHL18 ZNF764 TANC2 MGA TIAM2 ARID3B MTMR3 RASAL2 ZBTB24 BICD2 ZNF526 ANKHD1 C18ORF25 DLC1 UHRF1BP1 SLC25A37 HIVEP1 NBPF14 MICAL2 LGALSL LTBP2 MYSM1 DIP2B ANKRD50 SBF2 RASGRF2 CAPRIN2 INTS5 ZNF672 INTS1 GFOD1 LINC00511 BTBD3 DIDO1 KIAA0232 KIAA1549 ZNF275 BTBD7 PDLIM4 ZNF592 DNHD1 DNMBP NKILA UBE2O HSPG2 AC020916.1 CACNG8 NCKAP5L AL021578.1 AL353625.1 MORC2 AL591848.4 SH3BP5-AS1 AL118505.1 ZBTB7A AC002480.2 SLC2A3P1 ZNF248 AL356124.2 SLC25A30 MCM3AP PIAS2 GPR135 AC135050.6 PADI1 AC092835.1 OTUD4 DOCK5 RAPGEF6 RAI1 AHDC1 ZNF594 SNX33 AL451064.2 AC111000.2 LTO1 AC016831.6 HNRNPA1P33 CAPN15 AC103746.1 AC004918.5 IRGQ ZNF585A GJC1 ZNF805 AL160006.1 FBXL18 AL162615.1 HOOK2 AC024580.2 LINC01139 NBPF20 ONECUT3 CFAP251 DOHH KLHL36 MIR3680-1 AC004233.2 AL928654.4 CCDC163 DOCK7 SATB1-AS1 PRAG1 KMT2D ZSCAN16-AS1 FAM27E3 FBXL20 SDHAP1 AL353150.1 MINCR AC106820.4 RFX1 LMLN TUT7 ARL10 RPL41P5 AC145098.2 TTLL4 MMP25-AS1 PRR14L USP20 UBE2MP1 AC092828.1 FAM71F2 AP002748.4 AL132656.4 ZKSCAN2 AC092910.3 GTF2H4 SHANK2 AC067931.1 EBLN3P NBR2 AC080023.2 AC005534.1 POLRMTP1 AL117336.2 AC092306.1 WASH9P ZNF587B PPP1R26-AS1 RBBP4P2 AC037459.2 CTAGE15 ZNF562 RN7SKP296 AC010326.5 TENT4A BORCS8 PHKA1 GBA2 ZNF264 AC027514.1 PPM1L FUBP3 AC027031.2 ATP11A AC111170.4 KTN1-AS1 AC118344.4 AC107021.2 AL162171.3 AL161431.1 NDST2 LRRC37A SNTB1 AC018809.2 EIF4G3 PSORS1C3 KSR2 AL008721.2 POMK SUPT6H RESF1 HERC2P9 UBAP1L ADCY10P1 CELF1 PKD1P6 CROCCP3 AC022167.1 PSORS1C1 JOSD1 AC011476.3 AC007128.1 ZHX3 ZSWIM3 MFSD14C AC020658.6 LRCH1 C22ORF46 GARS-DT AL627309.6 BTNL9 AC009078.3 POLR2J2 AC011503.2 STARD7-AS1 LINC02035 CCDC69 AC106798.1 SNORA60 ZNF37A PRR7-AS1 AC007128.2 AC004076.2 AC027290.3 SLC25A51 ZNF112 RPL32P3 MPRIP CHD3 AC067968.1 ZC3H13 AL591895.1 AC073957.3 JHY TMEM117 CCDC9B AC102953.2 LRRFIP1P1 CUL9 KLRA1P 499 genes down-regulated by SARS-CoV-2 in Calu-3 cells from GSE148729 SARS-CoV-2 infection of Calu-3 cells Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sKZloen5y TBCA SUMO2 UBD SPINK1 ETFA UBE2D3 ACE2 ANXA3 IFITM1 ATP6AP2 RBX1 ZCRB1 KHK HLA-B UBE2D1 GGT1 TUBA1A CLTRN OAS1 ARL6IP6 TUBA4A SDF2 AGT SAP18 TSPAN8 NDUFB9 SRP72 HSBP1 ITM2A NEDD8 MAT2B RAB10 ARL14 MDH1 CREBL2 LRRC40 MRPL9 VAMP8 TPMT CLDN10 FBXO8 NDUFB6 ENY2 FBXL3 PSMA2 BTF3 OCIAD2 RPL24P4 RPS26 RPL35A CDK2AP1 TNFSF10 UQCR10 RPL10AP6 ARL3 AC099336.2 RPL41 RPL37 GPX2 FDCSP MT1E RPL7AP6 SPAG16 CFH AC116533.1 RPL30 COX6A1 RPL24 RPS25 TSTD1 SLPI NDRG2 COX7C AGR2 COPS9 VTCN1 CD24 MPZL2 STMN1 HLA-E TIMP1 NDUFB5 ATP5MC3 AURKB SPR CDK5 ANXA2P2 MT1F ATP6V1F SDHD RNASE1 CDK1 RPL26L1 SNX3 CCNB1 IFI27L2 SNORD3C DYNLL1 PRDX3 LIPA TCN1 CKS1B MANF APLP2 CYCS KRT14 CLU TMSB4X TMEM60 NUCB2 PSMA3 SAA1 UBE2T CFB PPM1N ARHGDIB MAD2L1 HMGB2 CENPE NEIL3 CTSS RAD51AP1 DNPH1 PSMB8 PPA1 EPHX1 PSME2 TSPAN13 YBX1 TMA7 COX17 CAPZB MYL12A TXN SYF2 GSTP1 ANAPC13 PSMB9 RPS23 CA2 SH3BGRL COX7A2L EIF3E HLA-DQB1 LYZ SNRPD2 CTSH EIF3K NDUFA13 PSMB6 PSMC2 PRDX5 VPS28 DNAJC8 DRAP1 LAPTM4A NDUFS6 ABRACL EID1 NDUFB3 RPL18 CD74 RPL35 SRP14 OAZ1 NDUFA5 NDUFB7 NDUFA2 ROMO1 TRMT112 PSAP NDUFC1 SMIM22 RPL36AL NDUFA6 ANXA1 UQCRHL HLA-DMA SRSF3 SAT1 NOP10 POLR2K SUB1 VBP1 NUDT16L1 NDUFC2 DBI SEC61G CD164 PGRMC1 HIGD2A CACYBP BNIP3L DEK CBX3 TMEM14B SNCG DPY30 NDUFS2 MAGT1 SNRPG PRR13 PDZK1IP1 TM4SF4 HAT1 CHMP5 S100A11 CRYZ ARL6IP5 PFDN2 SARNP PTTG1 TMX1 C12ORF57 YPEL5 UBE2N SMIM20 LAMTOR5 PSMB3 SRP9 TIPIN TFPT MAGOH AMZ2 PSMD10 CCDC58 ZMAT2 TPRKB UQCRQ PCNA BCAS2 WDR54 NDUFA8 NDUFA12 COMMD8 SSB STEAP1 POP5 NAA50 PSMA7 CMC1 UQCRH HMGN3 GMNN MMADHC SNHG6 AKR1B1 SEC11C ITGB3BP MRPL1 UBA3 TMSB10 HSPE1 SNRPE CUEDC2 SF3B5 TOMM5 RPL34 IER3IP1 MRPL18 GPBP1 TXNDC12 ARL6IP1 MNS1 AKR1B10 MSMO1 ZMPSTE24 MRPL47 RPA3 RDM1 SLIRP RIPK2 MUC20 TMEM229B TMEM126B DIRAS3 CCDC152 SEC62 TFPI2 SCOC CT83 LRRC31 PKIB RBM34 CX3CL1 PRSS3 CSTB MDK SERF2 COX5B SERP1 SIRT4 THAP2 SAA2 CCDC34 TIMM23 VTA1 PFDN4 PPA2 TIPRL PET100 RNF5 IDI1 C3ORF14 FAIM SELENOF TMEM11 TXN2 NDUFB1 FKBP3 ARPC5 COX16 GPN3 SPP1 RNF181 ATP5MD CHMP1B AURKAIP1 ATP5PD ATP5F1E C4ORF3 COMMD1 CIAO2A CCDC115 COMMD6 C11ORF58 NDUFAF4 BCCIP PON2 TRAPPC6A AGMO ANKRD22 HNRNPC CYSTM1 UROD IFT43 PUDP SELENOK MMP7 RLN2 GLYATL2 MPHOSPH6 SLC44A4 IFT57 FIS1 POLR2F MRPS22 SLCO1B3 GJB1 RIDA CCNG1 PSMA5 ZCCHC10 RWDD1 CDK7 CCNC TMEM59 TMEM14C SELENOT COX7B NDUFS5 MGST3 TIMM17A TIMMDC1 CHRNA5 SSBP1 RPL23AP42 SYTL3 COMMD4 LAGE3 PLEKHB1 POLR3K FEZ1 MRPS21 LANCL1 CCDC126 RSL24D1 TMEM156 NAA38 SPAG7 DMAC1 ECH1 LSM5 TMED7 H2AC11 AC246787.1 RN7SL832P NDUFC2-KCTD14 AL121594.1 NEDD8-MDP1 PSMC1P1 FRS3 H3C10 CENPX AC005258.1 AL645922.1 LSM3 CHCHD2P2 H1-2 AC011448.1 ZCCHC17 AL035458.2 PLAAT4 H2BC4 H2BC6 BEX3 H3P6 TMSB4XP8 ADH5P4 H3C13 EXOSC9 COX7CP1 H3C12 AC097625.2 TMCO1 AC073548.1 STK32A-AS1 MRPL50 H2AC21 H4C3 H1-5 H4C2 YBX1P10 SVIP H2AZ1 AL021546.1 RBBP9 AC124045.1 RPL36A-HNRNPH2 DERL2 FRG1 PEX13 AC005083.1 DNAH14 METTL5 PDCD5 AC008750.8 PPP1R2 HIRIP3 RPS28P7 RARA-AS1 ZNF85 BRD7P2 RNU5B-1 SMIM30 ST13P3 H2BC5 ERGIC2 EIF2S2P4 GATA6-AS1 LINC01144 COA6 AL445685.3 H2BC12 MIR1244-1 RNF5P1 DUSP23 C1GALT1C1 OTUD6B-AS1 ZNF576 AC009403.1 PYURF LOC107984142 RPL35P1 APBB1 AL138752.2 GABBR1 AC099661.1 AC087500.1 SYNJ2BP-COX16 CFAP298-TCP10L BCAP29 MED4 RETREG1 BLOC1S5 FANCL LINC01023 COX6A1P2 AP001816.1 COX20P1 AC078927.1 AK6 CRIPT HIGD1A TBPL1 FAXC MZT1 H2AC15 STYX TMEM38B LRRCC1 ELL2P1 SNORA32 IQCK PLPP5 SPA17 AC134682.1 ECHDC1 CENPQ 500 genes up-regulated by SARS-CoV-2 in Calu-3 cells from GSE148729 SARS-CoV-2 infection of Calu-3 cells Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/dipyP2G0H NKX3-1 RSRC2 SEC16B BIRC3 IL6 GDF15 CCL5 EGR1 UBD NMI TNF DDX58 IL1A CXCL10 IFITM3 CYP2J2 IFITM1 HLA-B NEDD9 LAP3 JAK2 KLF6 CLTRN IFNL3 SNIP1 OAS1 PTX3 HLA-C STAT1 HLA-A IFITM2 SRPK2 B2M MYCBP2 HERPUD1 APOBEC3G OASL TRIM31 MOV10 CXCL2 IFNB1 ISG15 ZNF503 NUB1 CXCL9 ARL14 MX1 MYD88 WFDC5 ZC3H12C NR3C1 LIFR CD55 PCLO MT2A TNFSF10 IFI27 DUSP16 EXT1 ZEB2 SNORD17 CFH RN7SL3 SERPINB2 HSPB8 SNORA73B TET2 ANKRD33B SEMA3A ISG20 GCNT4 ZBTB20 UNC93B1 TNFAIP2 PTGER4 KSR1 PARP10 HBEGF APOL1 TYMP BST2 SLC15A3 ITGAM APOL2 HLA-E AREG IFI44 SERPINB10 SLC1A3 EPSTI1 SPRY2 GRB10 APOL4 BATF2 RASGEF1B LINC00944 CXCL8 IL7R RNU4-1 G0S2 PTGS2 SCARNA5 B4GALT5 BMP2 GADD45B PLAUR FOXO1 WIF1 NAV2 ATF3 FZD4 CEBPB SLC12A7 HELZ2 NUAK2 OGFR RSAD2 OAS3 IDO1 IL10RA IRF7 CFB ZBP1 NLRC5 GBP5 TNFRSF9 TAP1 CCL20 IFIT1 SECTM1 CTSS ZNF442 CYP1A1 IFIT3 RTP4 HLA-F OAS2 XAF1 CH25H PSMB8 CD274 APOL6 GBP4 DHX58 C1R KYNU USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 MLKL LGMN STAT2 PML PLEKHA4 SOCS3 NFKBIE ADAR NT5C3A PARP9 PARP12 ARC SAMD9L GCH1 HSH2D ADM FAP IL4I1 INHBA RNF213 IFI35 PARP14 SOCS1 TRAFD1 SAMHD1 UBE2L6 TLR3 UBA7 FST SP110 ACKR4 SCN3A KLF4 ZFP36 LY6E FOS IGFBP4 IRF1 PSMB10 RASGRP3 DUSP1 TXNIP ICAM1 DTX3L NFKBIA IRF9 PSMB9 GBP3 JUN IFI44L SERPINB9 JUND ARRDC3 CD74 CCNL1 THEMIS2 SAT1 FSCN1 KDM6B CREB5 TRAF1 EGR2 IFNL1 PPP1R15A CSF1 TRIM22 JAKMIP3 TNFAIP3 HDAC9 DIAPH2-AS1 ZNF300P1 BBC3 NEURL3 DUSP5 IER5 TIPARP CSRNP1 MIR155HG CHAC1 MAFF NFKBIZ ZNFX1 FOSB PNPT1 MXD1 RPS6KC1 DNAJB4 NEAT1 TNFSF15 HIVEP2 C15ORF48 RND1 CHSY3 REL ABL2 TAP2 CIITA ASNS SLFN5 CASP1 PPM1K IL15RA GCA CD40 TRIM21 TAPBPL TRIM56 ZC3HAV1 TRIM5 TDRD7 TRIM14 TRIM69 MAP3K8 RIPK2 ACTN2 IKZF3 IRAK2 PDGFRL PRKD2 CXCL11 IFI6 SNORA21 GSDMB IL32 PER1 IFNL2 LAMP3 DDX60 RNF19B LGALS9 TNFSF13B XRN1 SP100 MX2 IFIT5 HERC5 TRANK1 DDX60L PSMB8-AS1 TMEM140 ADRB2 SAMD9 GBP1 SPAG9 MB21D2 HSD17B7P2 CD83 HES4 ETS2 CEACAM1 RELB RCAN1 ETV7 BTN3A3 GMPR NFE2L3 CLUHP3 PMAIP1 CX3CL1 HLA-DRA PATL1 ERAP2 SP140L ACHE APOL3 N4BP1 TMEM62 BTN3A1 HCP5 SOD2 MOB3C TRIM38 FAS FUT4 BLZF1 BTN3A2 IL12A OR52K3P PHACTR4 PIK3AP1 OPTN TRIM26 GLCCI1 PIK3R3 HRH1 KIAA0040 BACH2 SEMA7A NR4A1 IGF2 CD68 NCOA7 ETV3 HLA-H HLA-J MMD2 ANGPT2 C4A TENT5A BCL2L14 DICER1 PELI1 NFKB2 NEDD4 STK10 OTUD1 CYLD SMURF1 CITED2 EPHA4 GPCPD1 ERAP1 TEP1 SYNE1 MDGA1 PLK3 PODXL DAPP1 SNORA48 EPC1 SNAI1 PLXNA2 HLA-DOB RAET1L LRP2 ZBED5 DUOX1 KDM6A KMT2C COL11A2 HIP1R TTC26 CHD2 HLA-V ARHGEF38 TNFRSF10B AMBRA1 NOD1 RAB24 BTN2A2 NR2F1-AS1 HCG27 COL16A1 PLCG2 DCP1A FNDC3A PDZD2 EGOT PA2G4P4 UHRF1BP1 IFNL4 ZNF385C AFAP1 ENDOD1 UBN2 ZNF697 DNAH17 CNP FRS2 CASC19 SNHG3 AC107959.3 BAZ2B AC027290.2 NOCT AL021578.1 AL645922.1 PLAAT4 SNORA74A CPEB3 AF117829.1 SNORA70 PPP4R4 SCARNA6 RNU2-2P MED12L CFAP54 AC132217.2 RTL9 ZNF441 SNORD10 RNU4-2 LINC02701 RIPOR2 SHFL AC083837.1 GRIP2 AL669918.1 WARS1 SNORA73A LINC02068 SIPA1L2 SNORA63 SNORD3A SNORA71A GABBR1 MFSD14A TTC28 AC002480.1 DND1 H2BU1 AC015849.1 SYNPO2 PATL2 SLIT2 CFAP57 TAAR3P AL591222.1 SEMA3D H1-0 AC015688.4 RUFY4 H2AW HLA-K RNVU1-31 AL138787.2 NAMPTP1 AL645929.3 CRYZL2P-SEC16B TRPC4 MAFA RNVU1-28 RNU1-67P RANBP3L ZNF200 AC107959.1 CSKMT AC005070.3 STING1 IRF1-AS1 ST3GAL2 CPSF1P1 SNORD3B-2 VTRNA1-3 AC025580.2 AC022506.1 SNORA12 P3R3URF-PIK3R3 AC018644.1 SYDE1 KCNV1 AC109326.1 AC022034.1 SLC5A4-AS1 PAXIP1-AS2 AL109918.1 H2BC14 500 genes down-regulated by SARS-CoV-2 in Calu-3 cells from GSE148729 SARS-CoV-2 infection of Calu-3 cells Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/dipyP2G0H MYH9 IFNAR1 EEF1A1 ERMP1 MAPK3 NIN CAPN5 SPINK1 SUN2 CAPN2 ITGB1 KPNA2 MME RBL2 ARRB2 RNPEP MIPEP SCCPDH SLC30A9 VILL CENPF PMEPA1 USP13 AP2M1 CIT TUBA1A PLS1 ANXA13 CTSD TSPAN8 USH1C LGALS4 ITM2A HS2ST1 PRKAR2A CAT GGH TOP2B MDH1 GLO1 CREBL2 SLC25A40 CLDN10 SCP2 PTTG1IP METTL7A NDUFB6 ACO1 IFT122 CAV1 RNF128 NBEA SDC1 AK4 NT5DC2 PERP CFTR REPS2 BMPR1B SLC40A1 EEF1A1P5 UPK1B SH3BGRL2 TSPAN6 PBX1 TRIM2 MARCKS PLCE1 STEAP4 BCAS1 RPS25 SLC16A7 NDRG2 EXPH5 SORBS2 CHST9 COPS9 NFIA EMP2 SLC25A23 VTCN1 CD24 TAGLN2 ATP1A1 TMBIM6 STMN1 DHRS7 TGFBI PROS1 CMTM6 ABHD2 PLK1 DHCR24 TOP2A LMNB1 CCNB2 PLBD1 C5 CDKN3 NEK2 DEPDC1B HMMR ANXA2P2 SPAG5 ALCAM ANXA5 ARPIN BUB1B KIF14 KNSTRN ASPM AURKA FADS1 SHMT1 BIRC5 KIF4A COMMD9 SAPCD2 KIF15 PRR11 ATP5PB HDLBP TPX2 CCNB1 IDH1 CDCA3 LDHA SORT1 KIF20A SCD NCAPG PDGFD CRIP2 MLF1 AKR1C3 PTPRS TCN1 PBXIP1 TRAM1 ABCC4 APLP2 ABCD3 CYP24A1 HACD2 TPD52L1 SPDEF RAB4A ODAM PRC1 PTPRU CCDC85C ARHGAP11A CDC25C E2F8 CENPA CYFIP2 IQGAP3 PARPBP NCAPD2 NUSAP1 PBK CENPI ARHGDIB RACGAP1 SPC25 DEPDC1 CENPE SYT12 SNCA DHFR CCDC18 SERPINA3 SLC3A1 CD59 DPYSL2 LASP1 YBX1 TMA7 PPP1CB CAPZB RPLP0 CYB5A LYZ CTSH ACAT2 MYH10 PRDX5 SLC12A2 MORF4L1 EID1 VIM HADH MPC2 MXD4 GPI MYLK AGO1 GM2A VPS35 NUCKS1 DBI PGRMC1 BNIP3L OLFM4 PAH DMBX1 TMEM213 PLA2R1 PFKFB3 ANP32A ERI3 ATRAID TM4SF4 HMGB3 MRPL24 CRYZ ARL6IP5 POLD2 PTTG1 HMGB1 LAMTOR5 SRP9 GPR160 TMEM230 ANP32E HAVCR1 RCN2 LMAN1 GNG12 HSD17B2 PAM HTATSF1 SLC39A10 UQCRH CXXC5 DHX40 HMGN3 ETFB VAV3 SERINC5 TNFRSF19 ARL6IP1 MNS1 TBL1XR1 PIK3C2B AKR1B10 SRI INSIG1 MSMO1 HMGCR SQLE CD46 CDCA7 ITGAV MVD TNNT1 TNFAIP8L1 TFRC FGFR3 LBR PCSK9 SFXN3 SYT16 CFI VPS41 MBNL3 SUMF1 FAM149A ACP6 SLC26A2 IDH2 SEMA3E GALNT12 AHNAK2 NEB TRHDE EFHC1 MLEC CBX5 KIAA0100 TTC3 PCYOX1 DNAJC22 TMEM181 PRKACB VAT1 RALBP1 NOSTRIN HOGA1 GALM BRI3BP TM7SF2 CERK CMTM4 CHP1 PDXK SARAF ST6GAL1 PDK1 LMCD1 DNM1 CTNND2 ITGB6 ROR1 DPYSL3 KLK6 RARRES1 CCDC34 PRDX2 PGK1 COX11 IDI1 UGT2B7 ROS1 HFE SC5D GNPNAT1 TSN USP5 COPG2 SEPHS1 ARPC5 ADAM22 SPP1 GALNT1 NNT MYORG TPM1 SCD5 ALDH3A2 ASAH1 ATP5MPL AHNAK C4ORF3 ACAA2 ANXA4 CHMP3 COA3 GGCT LRRC20 DYNC2H1 HLTF OBSL1 MEGF6 KCNC4 TRAPPC6A ATP9A LSS KLHDC7A KLC4 MSI2 G6PD RTN3 MAP4 FARP1 UROD FDPS FDFT1 SFT2D2 PPARA SPOCK2 SREBF2 SEMA4G CMBL TEX15 ACACA LPP VWA2 PRSS12 SLC44A4 HOMER2 PTPRF SRD5A3 DTYMK TRIQK MBOAT2 NOTCH3 MYO1C TLR5 RNF130 PRKDC SESN3 CYP51A1 ICMT SERPINA4 HGD GJB1 LMO4 MAP3K20 XRCC5 GNPAT TMEM59 HNMT ACSF2 NYNRIN CTDSPL PALMD ANXA9 TMEM19 VANGL1 IKBIP NAALADL2 DARS2 ALDH7A1 HACD3 IARS2 GPC4 TNIK AIF1L CAPS KIF12 DHCR7 KCNMB4 NSDHL SAMD1 PMVK MMAB DSEL PLEKHB1 RERG MAOB GALNT10 EBP PGAP3 CARHSP1 STRBP DSC3 PXMP4 TBC1D5 CPD GPSM2 CD109 GPD1L HGSNAT LINC01963 BICC1 CCDC167 DMAC1 SPNS2 ECH1 DCAF11 MYOM1 NKILA GOLIM4 TRHDE-AS1 CRYZL2P GPR161 TLCD4 LSM3 NUDT3 AC068580.4 ARSD SEPTIN9 H2AZ2 PRXL2A NIPAL3 SGO2 SSPN SEPTIN2 H2AZ1 LNPK AC104532.1 CBX6 SPA17 PPP2R3A AC087721.2 MORF4L1P1 AC005332.6 GET1 APPL2 VMA21 ANKS6 CACNG4 IFT80 FAM168A TTC39C ERLIN2 CD99L2 ODF2 AL049839.2 PALM3 KIF1C TMEM41B TCTN1 TMCO3 NCMAP CCDC191 HMGB1P6 SWAP70 PAIP2B PDE1C OXCT1 AC000120.3 MMUT MBTPS1 HMGB1P5 HNRNPR ARHGEF9 PIMREG MGST2 500 genes up-regulated by MHV-A59 in murine liver cells from GSE146074 Murine coronavirus MHV-A59 infection of murine liver cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/Oj5DtXAgD MYH9 CYP3A13 RAD23B HSP90AB1 HSPA5 FGL2 CCL2 ATP6AP1 HYOU1 MVP STAT3 CTSL SQSTM1 VCP NMI IFI27L2B DDX58 TSPO YWHAZ NPC2 CXCL10 IFITM3 TPM4 PPT1 RNPEP YWHAB TPM3 TOR1AIP1 SLC22A18 COLGALT1 PKM COL4A1 ANXA2 LYN TUBB4B CDHR5 HSP90AA1 HMOX1 CALM1 PSMD4 UBQLN1 COPB2 SELENOS COL4A2 PSMC6 CTSD TARS STAT1 IFITM2 TMEM176A ISYNA1 B2M CNDP2 NPLOC4 MSN MOV10 ISG15 AGPAT2 ARF6 CXCL9 ENTPD5 G3BP2 RAB5C PSMB1 BPNT1 TLN1 ATP6V1B2 MCL1 PSMA2 ATP6V1G1 LCP1 SERPING1 CP CXCL1 KRT18 IFI27 HOPX PNRC1 CFH HSPB8 STEAP4 LCN2 KRT8 ABCA1 TAGLN2 UNC93B1 ITGB2 PDIA6 RMDN3 DDOST LGALS3BP SHC1 PGD C1QA GRINA FLNA TGFBI QSOX1 PROS1 CYBA BST2 PLOD1 MARCO PDIA4 TMED9 ARHGDIA GRN SLC6A6 PNP PLBD1 CTSB SLC16A1 GLRX SCPEP1 PSEN2 IFI44 ANXA5 CAPNS1 CTSZ C2 PDIA5 GLDC LGALS3 MMP19 OSTC PSMB2 HP RAPH1 PSMB7 ANG GSTM2 GSTM1 ZFP36L1 SERPINH1 MANF MPEG1 AXL ACTB PSMD6 LSR TSKU EPPK1 CLU TMSB4X HPX CTSC TNFRSF1A HELZ2 OGFR SAA1 RSAD2 IRF7 CFB ZBP1 IL18BP TAP1 PLD4 IFIT1 COTL1 DNASE1L3 CTSS FCER1G S100A9 IFIT3 RTP4 C3 XAF1 PSMB8 CD274 GBP4 DHX58 CD5L KYNU TREX1 USP18 CMPK2 IFIT2 COL3A1 PLAC8 APOF FGL1 HERC6 IFIH1 LGMN AMBP STAT2 RNASE4 TCIRG1 CLDN2 NAMPT TIFA GBP2 PARP9 PARP12 SAMD9L XDH GBP6 RNF213 IFI35 PARP14 TRAFD1 SAMHD1 PPA1 UBE2L6 UBA7 GBP7 SLC3A1 DDC PSME1 CLIC4 PSME2 GNAI2 PFN1 PTGES3 LASP1 SHISA5 LY6E TUBA1B ACTG1 IRF1 PSMB10 CHMP4B TGM2 CAPZB ICAM1 DTX3L SPARC GSTP1 MORF4L2 JUNB PSMB9 GBP3 ITM2C ALDH1A1 RPN1 PSMB6 PSMC2 LITAF PSMB5 RAP1B LAPTM4A PSMD3 TMEM176B TAPBP SH3BGRL3 VIM CD74 TYROBP RAN CCT3 CRELD2 CALR PSAP CFL1 LAPTM5 TUBB2A PSMA6 VDAC3 LRG1 SAT1 S100A10 CD151 LST1 FGB AOX1 SERPINA10 ZNFX1 PSMA4 PSMD1 M6PR S100A11 HSP90B1 PSMD13 PSMB3 STIP1 DPP3 VMP1 PSMC1 CTSO AHSA1 CAP1 PSMA1 PSMD14 PSMA7 SNX10 TMSB10 NARS SDF2L1 RSRP1 SRXN1 IK CD47 STAP2 NNMT TAP2 S100A8 LGALS8 TOR1AIP2 MOCOS GSDMD TAPBPL ZC3HAV1 SPPL2A TDRD7 MAP2K1 MRAP ACTN4 AARS HIST1H2BG ORM1 LPGAT1 CD302 LGALS9 CASP7 ST3GAL1 ARPC1B COPG1 CSTB PIK3AP1 U2AF1 CLIC1 BLVRB CD52 SARAF CD53 ACTR2 ACTR3 ST6GAL1 SAA2 CD68 C4B PSMC4 IFNAR2 HC PSMD7 PSMD11 SEC13 C8B ITIH4 ADGRE1 CRP CLPX KARS CPB2 DPP9 XBP1 TAX1BP1 ATP2A2 ESD USP5 TBRG1 ANXA7 EIF3D HTATIP2 ARPC5 PSMC5 MAPKAPK2 OAS1A PSMC3 APIP CALHM6 ATP1B3 CAPZA1 ARF4 CAPRIN1 CIAO2A ABHD4 ERAP1 DNAJB11 PTER PDIA3 FGA LBP HNRNPC GAS6 PSMD2 SELENOK CCL9 OASL1 SNX2 WDR1 SLC13A3 ITIH3 CLPTM1L CDC34 ACSM1 TXNRD1 IIGP1 IL6ST GSR RAB7 LRRC59 BHMT DAP UBR4 IL13RA1 GSTM3 UBXN4 GBF1 ORM2 APCS SERPINA7 GSTM4 C8A SAA4 C9 RRBP1 MT2 TRP53INP1 PSMA5 H3F3B TXN1 SLC35B1 UGDH SDCBP SELENOT NSFL1C H2-T23 IFI27L2A WFDC21 H2-D1 MT1 H2-AA H2-K1 SEC24D LY6D TMED7 LY6C2 TM9SF4 IGTP RNASET2B EMILIN1 EIF6 ACNAT2 PID1 H2-EB1 GBP9 H2-T22 CYP2C70 HNRNPU GM4070 H2-AB1 SERPINA3F H2-Q4 GM4951 ORM3 UGT1A6B H2-Q7 IRGM2 TUBB5 FCGR4 SEPT2_1 SLFN4 DBNL HIST1H2AB APOL9A SPCS2 HIST1H2BB LY6A GBP10 TRIM30A GSTM6 HIST1H2AP ACOX2 IFIT3B C1RA TGTP1 IFI47 C1S1 CES1B IFI204 GVIN1 LDHD VWA5A TGTP2 UGT1A6A H2-Q6 SLC41A2 IRGM1 SAA3 ALDOA_1 OASL2 SLC25A17 GM43302 UGT2B35 ALDH1A7 APON APOL9B SLFN2 PSMD12 GM49342 SERPINA3G MS4A6C UGT2B34 REXO2 C4BP IFI211 SERPINA3N OAS1G PRG4 500 genes down-regulated by MHV-A59 in murine liver cells from GSE146074 Murine coronavirus MHV-A59 infection of murine liver cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/Oj5DtXAgD DCTPP1 GCGR RPS27A FCGRT HECTD1 CTDSP1 ETFA RPL36 SLC27A2 OTC SCAP UGT2A3 ACADM NR1H4 TLE5 AHSG FABP1 FURIN F5 CES2E ENPEP PHB2 PKLR SPTBN2 RDX TST ACADVL CLEC4G NDUFB9 RETSAT POR HERPUD1 PCSK6 ALDOB AFM TTC38 EPHX2 VSIG4 ACADS REEP6 AFMID HYI AKR7A5 CISD1 IAH1 PROZ ALDH6A1 NDUFV1 NDUFB6 DDT GSTZ1 CPT1A GYS2 FECH ALB EIF4B VKORC1 RPS17 NDUFA10 RPL37A RPS16 RPL35A MT-ND3 AK4 PERP PIGR DDAH1 UQCR10 RPL14 ECM1 MT-ND1 MT-ND5 RPL41 MT-CO1 MT-ND6 FMO3 DEPTOR RPS8 HIST1H1E MT-ND2 MT-CO3 COX6A1 RPS25 RPSA RPS15 HIST1H4H RPL39 NDRG2 MT-ATP6 ACOT13 STARD10 MT-CO2 CCND1 TMBIM6 SLCO2B1 UQCRC1 DDRGK1 RETREG2 GPD1 NDST1 APH1A MRC1 AK2 NDUFB5 DHRS4 MRPL12 HADHA IGFBP2 SDHD FADS1 H1F0 GALK1 RGS16 GSTO1 DPYD HJURP ALDH9A1 ALDH4A1 ABCG5 RMND5A ABCG8 ABCC6 ABCD3 SERPINF1 SLC2A2 EHHADH COL14A1 ACOX1 GABARAPL1 CMTM8 HGFAC WDTC1 RXRA HSD11B1 ULK1 RAB43 EPN1 SOAT2 CYP2E1 NRN1 HMGCS2 GCH1 APOC2 PIPOX DBP INMT SORD RPL28 RPS28 RPL8 EPAS1 IGFBP4 PLTP ATP5G3 ELOVL5 PEBP1 EEF2 HPGD PTPRB CHCHD2 COX7A2L CYB5A H2AFZ RPL10A RPS21 NR1D2 NDUFA13 COX8A ATP5D PTP4A2 CCNI COX4I1 NDUFB11 BNIP3 HADH OAZ1 PEX6 NDUFV3 MRPL28 AQP1 MPC2 NDUFA1 NDUFA6 GM2A EIF4A2 IVNS1ABP NDUFA4 NOP10 NRP1 NDUFC2 ATP5C1 NDUFB10 HIGD2A S100A13 SLC38A4 SPP2 FTCD PAH TTR PROC BHLHE40 NDUFS2 DPM3 MRPL34 CRYZ MIF AIFM1 IDH3B PRDX4 SLC29A1 HMGB1 SLC25A11 RABAC1 AHCY SUCLA2 TPRKB UQCRQ MGLL UQCRH TMEM50A RPL32 RAB1B DECR1 ETFB TCP1 HSD17B11 GOT2 ITIH2 ETNK2 PTPRD BCHE ATP5E ATP5G2 C8G ACOT12 SLC10A1 APOA2 NR1I3 AGMAT GCHFR PTMS RGN BBOX1 ABAT TMEM56 IDH2 STARD4 SLC47A1 NDUFS1 DNAJC22 PAPSS2 HOGA1 GALM SERPINA6 PANK1 TM7SF2 MMD CHP1 UQCR11 COX6C PDK1 LPIN1 FADS2 UGT3A1 SLC38A3 NR1D1 DPYS ASPDH UGT3A2 PRODH2 AMDHD1 CXCL12 HPD STAB2 ACY3 GNA12 SDHA COQ9 AQP9 NPC1 FAAH SC5D STARD7 NEDD4 GRSF1 UGP2 PEX19 FMC1 BDH1 RNF13 SUCLG1 TMEM183A SZRD1 RDH16 ALAD APOC1 ALDH3A2 ATP5MD ADTRP ACAA2 ARL5A SLC25A10 STBD1 ECHDC2 RBP4 PINK1 ADI1 GPRC5C ABCB6 PEMT MPC1 SLC37A4 ACSL1 AGMO PPDPF CYC1 WBP1L KAT2B TMPRSS6 FAM91A1 GHR AGTR1A USF2 PPARA ACSM3 LIPC KLKB1 CHDH SIRT3 ABCA3 CUL4A EVA1A SERPINA1A UGT1A1 MT-ATP8 SLC19A2 TMEM106B EMC6 APOA5 SLC46A1 GSTT1 PPP2R5A ABCB4 UGT1A9 GCSH SLCO1B2 CYP3A11 XYLB APOC4 SLC27A5 UGT1A5 ABCA6 DMGDH CFHR2 AGXT HSD17B6 SLC25A47 BAAT SLC17A2 KLB IGFALS SLC16A2 POLDIP2 TEF RPS4X DHDH STARD5 PRDX6 HMGCL SELENOP MSRA SELENOO COX7B ECHS1 SLC25A20 ETFDH PDHA1 MT-CYTB SERPINA1B RPL10-PS3 HBB-BT SERPINA1D CHCHD3 NIPSNAP1 ATP5B LPIN2 PCYT2 DECR2 EBP GAMT TSPAN12 NDUFB8 VWA8 LPCAT3 EIF4EBP2 CLDN12 PDK2 ABHD14B ECI1 NME3 ECH1 IDH3G PLPP3 METTL26 KYAT3 BCKDHA ERG28 TTC39C KIF1C MMUT CAR5A ATP5K SUOX GM5617 GCDH SULT2A8 TIMM8A1 MLYCD CES1E ACOT3 C1RL CCDC107 GGACT GULO CYP2D22 CYP2A4 FCNA ACAD11 HDAC11 PRLR SARDH SLCO1A4 MUP3 SLC22A26 GSTT2 ACADL CYP2C37 RDH16F2 CAR3 CROT CYP4F15 CYP2C50 PCCB OAF ELOVL2 PCTP ACAA1B HBA-A2 ECI2 CYP2D26 CYP2A12 CYP2B13 LAMTOR4 BPHL ACAD8 ZDHHC9 GATD3A GM4756 CYP2A22 CYP4A10 2310039H08RIK CES1F PBLD2 SCRN2 GCAT_1 CES2A CYP2D10 NADK2 CYP2C23 NNT_1 UOX RDH9 NAT8F1 GSTT3 SLC25A13 CYP3A25 CES1D CYP4A14 GRCC10 EHD3 RELN AKR1C14 FBXO21 METTL7A1 MRPL14 ABCA8A CYP2C38 CYP2C29 MFSD4B1 1810058I24RIK ATP5O_2 AMY1 PRKD3 CYP2B9 PRXL2C CAR8 KYAT1 AC118710.1 SLC7A2 PBLD1 500 genes up-regulated by MHV-A59 in murine liver cells from GSE146074 Murine coronavirus MHV-A59 infection of murine liver cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/UB0sGwV5o MYH9 UBB RAD23B CD14 HSPA5 FGL2 CCL2 ATP6AP1 MVP VCAM1 STAT3 SUMO2 SQSTM1 UBD NMI IFI27L2B ITGB1 HIST1H1C DDX58 TSPO YWHAZ NPC2 CXCL10 IFITM3 TPM4 RNPEP IFITM1 TPM3 TOR1AIP1 PKM COL4A1 ANXA2 LYN TUBB4B DYNC1H1 HSP90AA1 SIRPA HMOX1 CALM3 CALM1 PSMD4 CFP COL4A2 PSMC6 CTSD HIST1H4A STAT1 IFITM2 TMEM176A B2M CNDP2 EIF2AK2 MSN MOV10 YWHAH ISG15 ARF6 CXCL9 MX1 MYD88 G3BP2 RAB5C TMBIM4 PSMB1 TLN1 ATP6V1B2 MCL1 PSMA2 ATP6V1G1 LCP1 CP CXCL1 KRT18 IFI27 HIST1H2BC HIST1H2AG PNRC1 HSPB8 STEAP4 HIST1H2BK PLA2G7 LCN2 KRT8 AIF1 TAGLN2 UNC93B1 ITGB2 TNFAIP2 C1QC PARP10 LGALS3BP PGD VASP C1QA GRINA FLNA TGFBI PROS1 CYBA CORO1B BST2 SLC15A3 MARCO TMED9 ARHGDIA GRN HK3 RHOB SLC11A1 TIMP1 PNP P2RX4 CAPG CTSB SLC16A1 IFI44 LGALS1 ANXA5 CAPNS1 CTSZ C1QB C2 LGALS3 DYNLL1 OSTC PSMB2 HP CCL4 CDKN1A SERPINH1 MPEG1 ACTB HMGA1 PSMD6 TSKU COL1A2 TMSB4X IRF8 HPX HIF1A UPP1 CTSC CEBPB TNFRSF1A HELZ2 OGFR SAA1 HCLS1 RSAD2 OAS3 IRF7 CFB ZBP1 IL18BP PLA1A GBP5 TAP1 PLD4 GZMA HIST1H2AD IFIT1 ARHGDIB HIST1H2AE CORO1A PTPRC COTL1 CTSS FCER1G FABP4 S100A9 IFIT3 RTP4 XAF1 PSMB8 CD274 GBP4 DHX58 CYBB IL1RN TREX1 USP18 CMPK2 IFIT2 COL3A1 PLAC8 FGL1 HERC6 IFIH1 MLKL LGMN AMBP STAT2 TCIRG1 SOCS3 NAMPT TIFA GBP2 PARP9 PARP12 SAMD9L XDH PIM1 GBP6 RNF213 IFI35 PARP14 TRAFD1 SAMHD1 PPA1 UBE2L6 UBA7 GBP7 WARS SLC3A1 PSME1 CLIC4 PSME2 GNAI2 PFN1 SHISA5 LY6E ACTG1 ATP6V0C IRF1 PSMB10 MYL12B CHMP4B TGM2 RHOG CAPZB MYL12A ICAM1 DTX3L NFKBIA SPARC GSTP1 BGN IRF9 MORF4L2 JUNB PSMB9 GBP3 JUN S100A4 CRIP1 CCT2 ITM2C PSMC2 ARPC3 PRDX5 ARPC2 LITAF PSMB5 RNF114 RAP1B LAPTM4A SERPINB9 S100A6 TMEM176B TAPBP SH3BGRL3 VIM PSMB4 TYROBP RAN CCT3 CRELD2 SLC39A1 PSAP CFL1 HEXA LAPTM5 TUBB2A IGFBP7 PSMA6 CAPZA2 VDAC3 LRG1 HCK THEMIS2 EFHD2 SAT1 POLR2K MARCKSL1 S100A10 CD151 CD9 LST1 FGB NOS2 SERPINA10 ZNFX1 OST4 PSMA4 CHMP5 M6PR S100A11 PSMD13 LAMTOR5 PSMB3 STIP1 MAGOH VMP1 PTMA AHSA1 CAP1 PSMA1 PSMD14 PSMA7 SSR2 PNPT1 SNX10 TMSB10 NARS HIST1H3G HIST1H1A SRXN1 CSRP1 CD47 HIST1H3B TAP2 S100A8 SLFN5 MOCOS GSDMD TAPBPL MAP2K1 CD38 NID1 HIST1H2BG ORM1 DDX60 RNF19B LGALS9 ARPC1B CSTB SOD2 PIK3AP1 SRGN SEC61B CLIC1 ARPC4 PTPN6 SERP1 CD52 CD53 GZMB ACTR2 PLEK ACTR3 SDC3 SAA2 CD68 VNN3 PSMC4 CCL12 IFNAR2 CCL7 SEM1 CLPX CPB2 XBP1 TAX1BP1 HIST1H1B GBA TBRG1 ANXA7 ACOD1 ARPC5 PSMC5 MAPKAPK2 OAS1A PSMC3 SPP1 SLC35F5 APIP CALHM6 ATP1B3 ASAH1 CAPZA1 ARF4 BUD31 CIAO2A IQGAP1 OASL1 WDR1 ITIH3 CDC34 IIGP1 GSR LRRC59 HIST1H2BJ CCL6 RANBP1 ORM2 APCS SERPINA7 SAA4 RRBP1 MT2 TRP53INP1 PSMA5 H3F3B TXN1 RHOC SDCBP SELENOW H2-T23 HIST2H2AA2 IFI27L2A H2-D1 MT1 H2-K1 GM10800 POLR2L DDX24 LY6D SNRPF LY6C2 IGTP RNASET2B EIF6 ACNAT2 GBP9 H2-T22 HNRNPU GM4070 SERPINA3F H2-Q4 ORM3 H2-Q7 IRGM2 TUBB5 FCGR4 SEPT2_1 SLFN4 DBNL HIST1H2AB APOL9A SPCS2 HIST1H2BB LY6A GBP10 TRIM30A HIST1H2AP IFIT3B C1RA TGTP1 IFI47 IFI204 GVIN1 TGTP2 H2-Q6 IRGM1 SAA3 ALDOA_1 OASL2 GM43302 APOL9B SLFN2 GM49342 SERPINA3G MS4A6C C4BP IFI211 SERPINA3N OAS1G PRG4 HIST2H3B MNDAL RNASET2A TRIM12A GBP8 CHIL3 FCGR1 WFDC17 HIST1H3F MS4A6B 7-SEP PIRB MS4A4C LILR4B HIST1H3C HIST2H3C2 IFI205 MS4A6D HIST1H2BM NT5C3 GM49339 SNX5 IFI209 MED21 FCGR3 PHF11D PHF11B HIST1H4J EIF1A DNAJA2 IL4RA TRIM30D 500 genes down-regulated by MHV-A59 in murine liver cells from GSE146074 Murine coronavirus MHV-A59 infection of murine liver cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/UB0sGwV5o DCTPP1 GCGR GLYCTK CTDSP1 CISD3 ETFA SLC27A2 AADAC OTC SCAP UGT2A3 UROC1 NR1H4 TLE5 CYB5B YIF1A GPT FABP1 KHK FURIN F5 GPX1 PHB2 PKLR RDX TST AGT AASS CYB5R3 NDUFB9 RETSAT POR PCK1 PCSK6 PMPCB MGAM ALDOB AFM EPHX2 CAT ACADS TKFC SCARB1 PAICS REEP6 GNMT SEPHS2 MDH1 FAH HYI LYPLA1 HIBCH AKR7A5 ADH5 CISD1 PTTG1IP IAH1 PROZ ALDH6A1 NDUFV1 DDT GSTZ1 CPT1A ACO1 GYS2 ALDH8A1 ADK DHRS1 ALB EIF4B VKORC1 NDUFA10 MT-ND3 PERP DDAH1 ASS1 ECM1 MT-ND1 MT-ND5 MT-CO1 MT-ND6 FMO3 DEPTOR MT-ND2 MT-ND4L MT-CO3 NDRG2 MT-ATP6 ACOT13 MT-ND4 STARD10 MT-CO2 SLC25A23 OGDH TMBIM6 SLCO2B1 UQCRC1 RETREG2 GPD1 NDST1 CLUH SULT1A1 AK2 NDUFB5 ME1 SQOR IGFBP2 VDAC1 SDHD FADS1 SHMT1 H1F0 GALK1 RGS16 HSD17B10 GSTO1 ASGR2 ECHDC3 DPYD IDH1 ALDH9A1 ALDH4A1 ABCG5 RMND5A KLF15 ABCC6 ABCC2 ABCD3 SERPINF1 SLC2A2 EHHADH ACOX1 CMTM8 HGFAC WDTC1 RXRA HSD11B1 EPN1 CYP2E1 ASGR1 NRN1 HMGCS2 GCH1 GCKR PIPOX DBP INMT SORD PCBP2 IGFBP4 PLTP SDHB ELOVL5 EEF2 HPGD UQCRC2 CYB5A NR1D2 ATP5D GSTA3 CCNI NSMF COX4I1 BNIP3 PDCD4 HADH OAZ1 MRPL28 AQP1 MPC2 MKNK2 GM2A EIF4A2 NRP1 OAT ATP5C1 NDUFB10 SLC38A2 HIGD2A SLC6A12 CYP1A2 SLC38A4 SPP2 FTCD PAH TTR TLCD2 PROC BHLHE40 NDUFS2 DPM3 CIDEB AIFM1 DCXR IDH3B PRDX4 SLC29A1 ASL AHCY SUCLA2 TPRKB HSD17B2 MGLL MCEE NIT2 LACTB2 UQCRH TMEM50A NDUFA9 ETFB PRPF8 HSD17B11 ACBD5 TOB1 GOT2 ITIH2 ETNK2 HACL1 BCHE MLXIPL C8G ACOT12 SLC10A1 APOA2 NR1I3 AGMAT GCHFR PTMS RARRES2 CYP8B1 BBOX1 ABAT TMEM56 IDH2 STARD4 SLC47A1 PCYOX1 NDUFS1 PAPSS2 MIA2 HOGA1 GALM SERPINA6 PANK1 PYGL CHP1 UQCR11 COX6C GNE CBS LPIN1 SEC14L2 UPB1 FADS2 UGT3A1 SLC38A3 NR1D1 DPYS ASPDH PRODH2 AMDHD1 CXCL12 HPD STAB2 ACY3 GNA12 MTSS1 SDHA COQ9 AQP9 NPC1 FAAH AKR1D1 SC5D STARD7 NEDD4 UGP2 FMC1 BDH1 AK3 RNF13 SUCLG1 TMEM183A RDH16 ABCB11 ALAD ALDH3A2 ACAA2 SLC25A10 MPST CCS STBD1 ECHDC2 RBP4 CPS1 ADI1 ABCB6 PEMT PRODH MPC1 SLC37A4 ACSL1 PPDPF CYC1 UROD WBP1L TMPRSS6 GHR AGTR1A USF2 PPARA LIPC KLKB1 APOC3 CHDH G6PC SEMA4G SIRT3 ECE1 CMBL PTPRF TTPA CUL4A EVA1A IVD ADIPOR2 UGT1A1 MT-ATP8 TMEM106B MTHFD1 APOA5 GSTT1 SEC24A PPP2R5A GCSH CYP2A5 CYP3A11 TTC36 XYLB APOC4 SLC27A5 ACSM5 SERPINC1 HGD UGT1A5 ABCA6 HAAO DMGDH CFHR2 AGXT MAT1A TDO2 HSD17B6 GJB1 BAAT SLC17A2 IGFALS SLC16A2 POLDIP2 SHMT2 TEF DHDH PRDX6 HMGCL SELENOP MSRA ECHS1 HBB-BS ETFDH PDHA1 ACSF2 MT-CYTB SERPINA1B HBB-BT SERPINA1D NIPSNAP1 ATP5B LPIN2 PXMP2 HS6ST1 PCYT2 SLC25A1 DECR2 MAOB EBP GAMT TSPAN12 VWA8 LPCAT3 EIF4EBP2 PDK2 TECR SDR42E1 ABHD14B ECI1 ECH1 IDH3G PLPP3 ATP5G1 METTL26 ATP5A1 PHYH KYAT3 BCKDHA ERG28 KIF1C MMUT CAR5A SUOX GCDH SULT2A8 CES1E ACOT3 CCDC107 GULO CYP2D22 CYP2A4 ACAD11 PRLR SARDH SLCO1A4 GSTT2 CYP2C37 RDH16F2 CAR3 CYP4F15 CYP2C50 PCCB OAF ELOVL2 PCTP ACAA1B HBA-A2 CYP2D26 CYP2A12 CYP2B13 BPHL ACAD8 ZDHHC9 GATD3A CYP2A22 CYP4A10 2310039H08RIK PBLD2 GCAT_1 CES2A CYP2D10 NADK2 CYP2C23 NNT_1 UOX RDH9 NAT8F1 GSTT3 SLC25A13 CYP3A25 CYP4A14 GRCC10 EHD3 AKR1C14 METTL7A1 ABCA8A CYP2C38 CYP2C29 MFSD4B1 ATP5O_2 AMY1 PRKD3 CYP2B9 CAR8 KYAT1 AC118710.1 SLC7A2 PBLD1 HAL CYP2C54 HAMP2 PEX16 FGGY NUDT7 MUP22 IQGAP2 MUP11 CYP2C69 PECR CYP4F13 ISOC1 AOX3 AKR1C6 ADH1 AKR1C12 UPP2 HBA-A1 ATP11C 6-MAR CYP2C68 CYP4V3 HSD3B3 AMT SIDT2 500 genes up-regulated by MHV-A59 in murine spleen cells from GSE146074 Murine coronavirus MHV-A59 infection of murine spleen cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/xtiAziXb4 NUP210 UBB CD79B SUMO1 IMPDH2 HSP90AB1 HSPA5 CNTRL HYOU1 MVP ZC3H7A SUMO2 LARP1 VCP RPL12 RPL36 CSDE1 DDX58 UBC YWHAZ DDX21 NPC2 RHOA YWHAG IFITM3 TPM4 TPM3 PKM HSPA4 COL4A1 LYN TUBB4B DYNC1H1 UBA1 NCL HSP90AA1 SIRPA CALM1 FBL CFP CTSD STAT1 TRIM25 VARS CANX B2M MFGE8 MYCBP2 EIF2AK2 NPM1 MSN FERMT3 ISG15 HSPA8 EVL PPIA MX1 SPTBN1 NAP1L1 TLN1 ATP6V1G1 RPS20 BTF3 ENO1 LCP1 RPS17 RPL21 RPL35A RPL9 RPS11 RPL14 RPL27 RPS24 RPL6 HIST1H1E HIST1H2BK RPL23 RPL24 RPS25 RPL39 RPS18 RPL19 RPL7A AIF1 IGLC2 RPL31 RPL11 RPS7 RPS27 RPL27A TAGLN2 UNC93B1 ARHGAP30 ATP1A1 ITGB2 PDIA6 C1QC USF1 VASP C1QA AKT1 SNRPB TGFBI CYBA CORO1B BST2 ITGAL EIF3B PDIA4 ARAP1 TMED9 GRN HK3 PPP1R12C CCT5 TOP2A SDC4 CTSB SDHD CTSZ C1QB EPSTI1 CCT8 EIF4G1 GAPDH COX5A MKI67 LDHA HINT1 TRAM1 COL1A1 ZFP36L2 MPEG1 ACTB CXCL13 LAMP1 IRF8 RAP1A CTSC HELZ2 OGFR HCLS1 PTPN22 RSAD2 OAS3 IL10RA IRF7 CFB LAX1 ZBP1 CYFIP2 NLRC5 TAP1 PLD4 IFIT1 ARHGDIB PTPRC HMGB2 FYB MYO1F CTSS FCER1G S100A9 IFIT3 OAS2 C3 PSMB8 CD274 COCH GBP4 DHX58 CYBB CD5L USP18 IFIT2 COL3A1 PLAC8 HERC6 LGMN STAT2 PML TCIRG1 ADAR GBP2 PARP9 SAMD9L DAXX GBP6 RNF213 IFI35 PARP14 TRAFD1 SAMHD1 UBA7 GBP7 SP110 PSME1 FTH1 CLIC4 PSME2 RPL28 PFN1 PTGES3 SHISA5 YBX1 LY6E TUBA1B ACTG1 AKR1A1 IRF1 PSMB10 CHMP4B TGM2 DTX3L SPARC BGN ITM2B GBP3 DAZAP2 RPS23 RPLP0 P4HB EIF3E H2AFZ CST3 MAT2A CCT2 MDH2 RPL26 GDI2 PPIB RPL4 PSMB6 ARPC2 NME2 EIF5A RNF114 RAP1B LAPTM4A TAPBP SH3BGRL3 CCT4 ATP5H VIM MBNL1 PCNP NDUFB7 TYROBP GIMAP4 CCT3 TALDO1 CALR PSAP CFL1 COX6B1 CCNL1 IL2RG DNAJA1 DSTN CAPZA2 WNK1 GNS HCK THEMIS2 EEF1G SLC25A3 SAT1 SET NUCKS1 SSR3 CD164 SERINC3 TMED2 EIF3C DEK SLA CCND2 LRRK2 FILIP1L TNFRSF14 ZNFX1 MOB1A M6PR SEC61A1 HSP90B1 IDH3B PA2G4 STIP1 PTMA SLC25A5 SSB CAP1 PSMA1 BZW1 PSMA7 CCT7 PAPOLA STAG2 HSPE1 RPL32 RPL29 RPL34 GNA13 TCP1 GPBP1 PTBP3 FKBP4 HSPD1 ARL6IP1 NUFIP2 HIST1H1A SETD2 IK HDGF CSRP1 CD47 HIST1H3B TAP2 SLFN5 GSDMD USP25 ZC3HAV1 SELL MAP2K1 TNFRSF13C POU2AF1 BTLA CD38 BIN2 HNRNPF FNBP4 SMG1 TPR EIF3A SP100 HNRNPA2B1 PRRC2C ATRX MTPN ARPC1B ANP32B SMCHD1 BLNK PIK3AP1 RPL23A U2AF1 SRGN EIF4A1 CLIC1 PTPN6 SERP1 SF3B1 CD52 CASP8 CD53 HNRNPA1 EIF4G2 ROCK1 NONO ACTR2 PLEK MS4A1 EVI2B SDC3 NCF1 CR2 C4B SF3B3 PGK1 PTPN1 PRKCD SEM1 RANBP2 ARF5 XBP1 FAM111A HIST1H1B PAX5 SP140 MAPKAPK2 SZRD1 CLTC CAPZA1 CGGBP1 CCT6A ZC3H15 PDIA3 TMEM123 IQGAP1 NOP56 ITPR1 PPP1R12A PSMD2 DHX9 OASL1 SNX2 WDR1 SSRP1 SMC4 IIGP1 BANK1 UBR4 CLEC2D RRBP1 BIRC6 MYBBP1A HNRNPAB DOCK2 NRROS HSPA9 TXN1 SELENOT PLCG2 H2-T23 LYZ2 IFI27L2A GM2000 H2-D1 RPL10-PS3 H2-K1 ATP5B ARHGAP17 DDX24 PHIP RSL24D1 CNP KAT6A ATP5A1 TUT4 HNRNPA3 LY6C2 IGTP GBP9 H2-T22 GM4070 H2-Q4 H2-Q7 IRGM2 TUBB5 SLFN4 HIST1H2AB HIST1H2BB LY6A TRIM30A IFIT3B IFI47 IFI204 GVIN1 TGTP2 H2-Q6 IRGM1 ALDOA_1 OASL2 SLFN2 SERPINA3G HIST2H3B MNDAL TRIM12A GBP8 MS4A6B 7-SEP MS4A4C HIST1H3C SNX5 IFI209 TRIM30D GPI1 FCRL1 D8ERTD738E IFIT1BL1 H2-T24 DOCK10 KIF5B TRIM34A BC005537 SUPT16 SLFN8 BAZ1B 9930111J21RIK1 TRIP12 FCMR EIF3M SLFN1 EIF2S3X GM11808 GIMAP6 9930111J21RIK2 GM49369 2610507B11RIK IFI206 XRN2 PNRC2 ILRUN IFI203 SCD1 ETNK1 H2-Q5 PSME2B H2-M3 IFI213 500 genes down-regulated by MHV-A59 in murine spleen cells from GSE146074 Murine coronavirus MHV-A59 infection of murine spleen cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/xtiAziXb4 MYH9 EIF4H JAK1 RPS27A EEF1A1 EIF3F VCAM1 HECTD1 SPOP SPTAN1 SUN2 ITGB1 DDX5 HIST1H1C AKAP8 RPL13 MACF1 TLE5 ARRB2 EZR YWHAB RASA3 EPS15 CTNNB1 NFKB1 HMOX1 GPX1 BRD2 RBCK1 H3F3A CALM3 PHB2 GRIPAP1 ING4 FMNL1 TRIM28 FAU PABPC1 ITGA4 ELK4 YWHAH AKAP8L MAP3K1 DIAPH1 ARF6 CSNK2A1 DCAF7 USP7 SLC44A2 EDEM1 STAT6 GRB2 RBM39 CD55 SF1 STXBP2 MCL1 EIF4B PFDN5 RPL37A RPS26 RPS16 MT-ND3 RPLP2 TENT5C SLC40A1 MT-ND1 MT-ND5 RPL41 TPT1 MT-CO1 MT-ND6 RPL37 RPS8 RPL38 PNRC1 MARCKS RPL30 MT-ND2 MT-ND4L RPL13A MT-CO3 RPSA RPS15 HIST1H4H UTRN RPS13 MT-ATP6 ABLIM1 MT-ND4 RPS29 MT-CO2 RPLP1 RPS14 RPL7 SRRT MAN2B1 TMBIM6 LSP1 MYO1G PTPA ARHGAP4 ADCY7 PARVG NUMA1 FLNA PTK2B FKBP8 CD37 GRK2 CD81 SPN PPP6R1 EHBP1L1 ADGRE5 MARCO TBC1D10C ITPKB ARHGDIA CMTM6 SNRNP70 SLC1A5 HVCN1 DDIT4 MZB1 FGD2 MAFB CLTA JCHAIN KLF2 ZFP36L1 STK4 RPS2 AXL SRSF1 ITPR3 CLU TMSB4X INPP5D HNRNPH1 PNN HNRNPK SAFB SORL1 NOTCH2 EPN1 LAT SELPLG DENND1C RASAL3 LCK PTPRCAP CCDC88B ITGB7 RAC2 CD72 CORO1A CD2 VAV1 ALAS2 CD19 NFKBIE IRF2 BTG2 ETS1 PCBP2 GNAI2 TSPAN13 RPL8 CNN2 HNRNPM ATP5G3 EEF2 SIPA1 CAPZB TXNIP NFKBIA MRFAP1 U2AF2 CHCHD2 COX7A2L RPL3 RPL5 RPS19 S100A4 EEF1B2 RPL10A ITM2C LUC7L3 BTG1 RPS5 CTSH EIF3K RPL22 RPS10 PPP1CA PTP4A2 HNRNPUL1 MORF4L1 GLUL CCNI JUND GIMAP8 COX4I1 RPL18 PABPN1 BRK1 DDX3X PDCD4 CD74 RPS9 CNBP DHX15 RPL15 DDX17 OAZ1 H2AFY RPL18A SOD1 CSF1R ATF4 ATP6V0B LIMD2 ARF1 LAPTM5 IGFBP7 MKNK2 RPL36AL LBH RBM3 GM2A EIF4A2 RPS3 IVNS1ABP SRSF3 CCNL2 DDX39B ANAPC5 WASF2 NXF1 GPX4 ZDHHC18 BNIP3L CBX3 MAP4K1 IKZF1 CYTH4 LIMD1 PPP1R15B TAF1D NDUFS2 PRR13 MRPL24 ACIN1 NRBP1 PSME3 EMG1 ATP5L FAM107B UQCRH PPP1CC TMSB10 ARHGEF18 PRPF8 ODC1 RSRP1 SRSF2 LENG8 SRSF7 HNRNPA0 SRSF6 ANKRD13A ATP5E CIITA CSK TRAF3IP3 WDFY4 SPIB ACAP1 CCNB1IP1 PRPF38B HIST1H4F DHX16 ARID4A DNAJC7 STX16 RPL22L1 MLEC CHD4 PIK3R1 UCP2 ASH1L PNISR HNRNPL SRRM2 GLUD1 GTPBP2 ACTN1 MYL6 ARPC4 GPSM3 EIF1 SNN SARAF S1PR1 RPS6 RPL17 LTB CRLF3 SON PRKAR1A SRSF5 RPL36A ACTR3 ATF7IP CLK1 APOE APBB1IP B4GALNT1 ACP5 IFNGR1 SDHA PIK3CD ARHGAP45 DOK3 BSG CXCR4 PARP1 SYK NFKB2 TXNDC5 PPP4C COPA ARPC5 LSM14A STK10 CYTH1 AUP1 ATP1B3 CDC42 AHNAK CDC42SE1 ANKRD11 HNRNPUL2 MTA2 GOLGA4 CHST3 AKAP13 MAZ POLR2A HNRNPC SMAP2 MYO9B RAPGEF1 RBM6 TCF25 UBTF HIST1H3A JMJD1C CBL EHMT2 NSD1 TRA2A CHD2 VSIR H2-OB RAB7 MYO1C ATP2A3 RACK1 BLK CYB561A3 ERBIN MT-ATP8 CD79A DNM2 GIMAP1 HUWE1 SETX PPP2R5A PPP1R9B UGCG TRP53INP1 CDK11B HP1BP3 RCC2 RPS4X NOP53 GRK6 AKNA ARHGEF1 DOCK8 TMEM14C SELENOP SELENOW HBB-BS CS HIST2H2AA2 MT-CYTB RPS27RT H2-AA HBB-BT RPS3A1 GM10800 EIF3H ITSN2 KDM5C FAM168B KIF21B CLK4 ANXA6 LRMP STK17B LY6D EIF4EBP2 HNRNPDL OTULIN HIPK1 SLTM CDC42SE2 WAPL GRAMD1A MAP4K2 JPT1 KMT2E PIP4K2A RBM5 ATPIF1 BRWD1 RIPOR2 KMT2D CELF1 CHD3 SWAP70 H2-EB1 H2-AB1 DBNL HIST1H2AP FCNA HBA-A2 IL4RA HBA-A1 PRKCB RBM25 GRAP DGKA ZFP740 BAZ2A DDX6 FCER2A HIST1H3I 1-SEP ZFP207 GM10718 FGFR1OP2 OGA HIST1H4M GDI1 GM16286 PRRC2A H2-DMB2 GM21738 EIF5 MAN1A ARPC5L SAFB2 DGKD PKN1 GM10721 FCHSD2 RBM12B2 GM38394 IST1 FAM120A TCF20 CCDC88C GPBP1L1 UBE2D2A CD24A TMEM131L FTL1 PLEKHA2 ESYT1 WDR26 SIGLECG ARHGAP15 DDX23 H2-DMB1 GIMAP3 SF3B2 PRPF4B TRIR ZFC3H1 FNBP1 SBF1 SH3BP5 VAV2 GM10801 CCL21A RNF10 500 genes up-regulated by MHV-A59 in murine spleen cells from GSE146074 Murine coronavirus MHV-A59 infection of murine spleen cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/nclfn5P6H UBB IMPDH2 HSP90AB1 HSPA5 FGL2 HYOU1 VCAM1 SUMO2 SQSTM1 VCP RPL12 RPL36 PPP2R1A KPNA2 HIST1H1C TSPO UBC RPL13 NPC2 CXCL10 IFITM3 PF4 PKM YWHAE COL4A1 ANXA2 TUBB4B LAP3 UBA1 AP2M1 HSP90AA1 HMOX1 H3F3A CALM1 UBA52 FBL PSMD4 COPB2 CFP TUBA1C CTSD HIST1H4A STAT1 IFITM2 B2M MFGE8 CNDP2 NDUFB9 ELOB FERMT3 ISG15 HSPA8 PPIA CHMP2A RAB5C TLN1 ATP6V1G1 RPS20 BTF3 ENO1 LCP1 RPS17 SERPING1 RPL37A RPS26 RPL21 RPL35A HIST1H2BH HIST1H4B RPS12 RPS11 RPL14 HIST1H2BC RPL27 MT-ND1 RPL41 RPS15A MT-CO1 RPL6 RPL37 HIST1H2AG HIST1H1E HIST2H2AC RPL30 HIST1H2BK MT-ND2 MT-CO3 COX6A1 RPL24 RPS25 RPSA HIST1H4H SLPI RPL39 RPS13 MT-ATP6 RPS18 LCN2 MT-ND4 RPS29 RPL7A IGLC2 MT-CO2 RPL31 RPL11 RPS27 RPL27A TAGLN2 ATP1A1 ITGB2 PDIA6 C1QC DDOST LGALS3BP UQCRC1 PGD C1QA SNRPB GNB2 TGFBI CYBA CORO1B BST2 EIF3B GANAB TKT PDIA4 TMED9 GRN HK3 DDB1 SYNGR2 CCT5 TOP2A LMNB1 CTSB AP2S1 LGALS1 ANXA5 MCM2 MZB1 SDHD RRM2 CTSZ C1QB PRDX1 CCT8 GAPDH LGALS3 COX5A OSTC PSMB2 HP LDHA TPI1 PSMB7 CAMP HINT1 MPEG1 ACTB HMGA1 CXCL13 CLU LAMP1 CTSC CD48 OAS3 IRF7 CFB SELPLG ZBP1 GBP5 TAP1 PLD4 HIST1H3D GZMA HIST1H2AD MCM5 ARHGDIB HIST1H2AE RAC2 H2AFX CORO1A HMGB2 COTL1 CTSS FCER1G S100A9 IFIT3 C3 PSMB8 COCH GBP4 CYBB CD5L TREX1 USP18 PLAC8 LGMN STAT2 PML GBP2 GBP6 RNF213 IFI35 PARP14 TRAFD1 PPA1 GBP7 PSME1 FTH1 PCBP2 PSME2 RPL28 GNAI2 RPS28 PFN1 UQCRB PTGES3 RPL8 YBX1 LY6E TUBA1B ACTG1 AKR1A1 ATP6V0C IRF1 PSMB10 ATP5G3 CHMP4B EIF3G SDHB TGM2 CAPZB PLVAP ICAM1 SPARC GSTP1 BGN PCBP1 ITM2B PSMB9 GBP3 DAZAP2 CHCHD2 RPLP0 RBBP7 UQCRC2 P4HB H2AFZ CST3 CRIP1 PLIN2 EIF3I MDH2 RPL10 RPL26 RPS21 RPS10 PPIB RPN1 GABARAP PSMB6 COX8A ARPC3 PRDX5 ARPC2 NME2 EIF5A PPP1CA VDAC2 PSMB5 RAP1B C1QBP PSMD3 SH3BGRL3 CCT4 COX4I1 RPL18 VIM RPL15 NDUFB7 PSMB4 RPL18A TYROBP NDUFA2 SOD1 RAN CSF1R CCT3 TALDO1 CRELD2 CALR PSAP CFL1 HEXA ARF1 COX6B1 IL2RG IGFBP7 PSMA6 RPL36AL EDF1 TMED10 HCK THEMIS2 SLC25A3 NDUFA4 RPS27L S100A10 ATP5C1 EIF3C NAPSA GPX3 UBE2S PSMA4 M6PR S100A11 SEC61A1 HSP90B1 MIF PGAM1 IDH3B PA2G4 PSMB3 STIP1 AHCY NHP2 PCNA PTMA SLC25A5 AHSA1 ATP5L CAP1 PSMA1 PSMA7 CCT7 SEC11C RPN2 HSPE1 RPL32 RPL29 RPL34 SDF2L1 PRPF8 TCP1 ODC1 HIST1H3G NUDC FKBP4 HSPD1 ARL6IP1 HIST1H4C HIST1H1A HIST1H3B S100A8 POU2AF1 ACTN4 HNRNPF HIST1H3H HIST1H4D HIST1H2BL HIST1H4F HIST1H2BG LGALS9 ARPC1B CSTB RPL23A U2AF1 SRGN SEC61B MSRB1 EIF4A1 COPE CLIC1 COX5B PTPN6 HMGN2 CD52 CD53 GZMB HIST1H2BF C4B PGK1 PSMC4 TIMM23 SEC13 SEM1 KARS BSG XBP1 HIST1H1B TXNDC5 EIF3D COPA PHGDH OAS1A PSMC3 CAPZA1 CCT6A MRPL52 PDIA3 RALY PSMD2 WDR1 SSRP1 HIST1H3A IIGP1 GSR HIST1H2BJ MT-ATP8 CD79A LY6C1 PTBP1 RANBP1 PSMA5 MYBBP1A HNRNPAB SHMT2 HSPA9 TXN1 TMEM14C SDCBP CS H2-T23 HIST2H2AA2 LYZ2 MT-CYTB IFI27L2A GM2000 H2-D1 RPL10-PS3 H2-K1 EIF3L ATP5B LY6D ATP5A1 LY6C2 IGTP GBP9 H2-T22 GM4070 H2-AB1 SERPINA3F H2-Q7 IRGM2 TUBB5 FCGR4 SLFN4 HIST1H2AB HIST1H2BB LY6A TRIM30A HIST1H2AP TGTP1 IFI47 IFI204 GVIN1 TGTP2 IRGM1 ALDOA_1 OASL2 GM49342 SERPINA3G MS4A6C IFI211 ATP5K HIST2H3B GBP8 CHIL3 WFDC17 HIST1H3F MS4A4C HIST1H3C HIST2H3C2 HIST1H2BM FCGR3 HIST1H4J GPI1 D8ERTD738E FCMR GM11808 GM49369 HIST1H3I HIST1H4M HIST1H2BN HIST1H4K NGP HIST1H3E HIST2H2BB ATP5F1 AKR1B3 GM10053 HIST1H2AF HIST1H2AH HIST2H2AA1 HIST1H2AN HIST1H2AK RETNLG HIST1H4N 500 genes down-regulated by MHV-A59 in murine spleen cells from GSE146074 Murine coronavirus MHV-A59 infection of murine spleen cells, effects can be compared to those of SARS-CoV-2 Source paper citation missing BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/nclfn5P6H MYH9 EIF4H CD79B JAK1 SUMO1 RPS27A EEF1A1 EIF3F HECTD1 SPOP SPTAN1 SUN2 CSDE1 KPNB1 ITGB1 DDX5 AKAP8 YWHAZ MACF1 RHOA YWHAG ARRB2 EZR TPM4 YWHAB TPM3 RASA3 LYN DYNC1H1 NCL CTNNB1 NFKB1 BRD2 CALM3 VARS FMNL1 MYCBP2 TRIM28 FAU PABPC1 ITGA4 GNB1 ELK4 MSN MAP3K1 DIAPH1 ARF6 DCAF7 EVL LNPEP USP7 SLC44A2 EDEM1 STAT6 SPTBN1 GRB2 NAP1L1 RBM39 CD55 MCL1 EIF4B MT-ND3 RPL9 TENT5C SLC40A1 RPS24 TPT1 MT-ND6 PNRC1 MARCKS RPL13A UTRN ABLIM1 RPS14 RPL7 SRRT UNC93B1 ARHGAP30 MAN2B1 TMBIM6 LSP1 MYO1G PTPA ARHGAP4 ADCY7 PARVG VASP NUMA1 PTK2B FKBP8 CD37 GRK2 CD81 SPN PPP6R1 ITGAL ADGRE5 TBC1D10C ARAP1 ITPKB CMTM6 SNRNP70 AK2 SDC4 HVCN1 DDIT4 MAFB CLTA MKI67 KLF2 TRAM1 ZFP36L1 STK4 COL1A1 ZFP36L2 AXL SRSF1 COL1A2 TMSB4X INPP5D HNRNPH1 RAP1A HNRNPK SORL1 NOTCH2 EPN1 HCLS1 LAT SASH3 IL10RA LAX1 CYFIP2 RASAL3 LCK PTPRCAP ITGB7 PTPRC FYB CD2 VAV1 ALAS2 CD19 COL3A1 NFKBIE SAMD9L UBA7 SP110 BTG2 CLIC4 ETS1 TSPAN13 SHISA5 HNRNPM EEF2 SIPA1 TXNIP NFKBIA MRFAP1 U2AF2 COX7A2L RPL3 RPL5 RPS19 EIF3E S100A4 MAT2A EEF1B2 ITM2C BTG1 RPS5 CTSH GDI2 RPL4 PTP4A2 HNRNPUL1 MORF4L1 GLUL CCNI JUND GIMAP8 PABPN1 BRK1 DDX3X PDCD4 MBNL1 CD74 RPL35 TSC22D3 RPS9 CNBP DHX15 DDX17 OAZ1 H2AFY GIMAP4 ATF4 ATP6V0B LIMD2 LAPTM5 MKNK2 DSTN WNK1 LBH RBM3 EEF1G EIF4A2 RPS3 IVNS1ABP SRSF3 SAT1 CCNL2 DDX39B NUCKS1 ANAPC5 NXF1 SSR3 SERINC3 GPX4 ZDHHC18 BNIP3L DEK CBX3 MAP4K1 SLA CCND2 LRRK2 IKZF1 CYTH4 LIMD1 PPP1R15B NDUFS2 PRR13 MOB1A ACIN1 PSME3 EMG1 SSB FAM107B BZW1 UQCRH PAPOLA PPP1CC TMSB10 ARHGEF18 PTBP3 RSRP1 OGT SRSF2 LENG8 SRSF7 HNRNPA0 SETD2 HDGF SRSF6 ATP5E CSRP1 CD47 TAP2 CIITA CSK ZC3HAV1 SELL TNFRSF13C IKZF3 BTLA NCKAP1L TRAF3IP3 WDFY4 SPIB ACAP1 KLHL6 BIN2 PRPF38B SMG1 TPR EIF3A DNAJC7 SP100 HNRNPA2B1 RPL22L1 MLEC CHD4 PRRC2C PIK3R1 UCP2 PNISR HNRNPL SRRM2 ANP32B BLNK ACTN1 ARPC4 GPSM3 EIF1 SNN SERP1 SF3B1 SARAF S1PR1 RPS6 HNRNPA1 EIF4G2 ROCK1 RPL17 NONO LTB CRLF3 ACTR2 SON MS4A1 PRKAR1A SRSF5 ACTR3 CLK1 SDC3 NCF1 APBB1IP B4GALNT1 CR2 SF3B3 IFNGR1 PTPN1 PRKCD RANBP2 PIK3CD ARHGAP45 DOK3 ARF5 CXCR4 PARP1 FAM111A TAX1BP1 SYK PAX5 RTCB PPP4C ARPC5 MAPKAPK2 LSM14A STK10 CYTH1 AUP1 ATP1B3 CDC42 AHNAK CDC42SE1 ANKRD11 HNRNPUL2 MTA2 TMEM123 CHST3 AKAP13 MAZ POLR2A IQGAP1 HNRNPC SMAP2 RRP1 NOP56 RAPGEF1 SLC39A7 TCF25 DHX9 EWSR1 CBL EHMT2 NSD1 SMC4 TRA2A CHD2 VSIR H2-OB RAB7 TARDBP MYO1C ATP2A3 BANK1 BLK CYB561A3 ERBIN CD22 UBR4 GIMAP1 CLEC2D HUWE1 PPP2R5A PPP1R9B SFPQ RRBP1 TRP53INP1 RCC2 RPS4X NOP53 GRK6 DOCK2 AKNA ARHGEF1 DOCK8 H3F3B SELENOT SELENOP SELENOW PLCG2 HBB-BS RPS27RT H2-AA HBB-BT RPS3A1 GM10800 EIF3H FAM168B KIF21B ANXA6 LRMP STK17B EIF4EBP2 KAT6A HIPK1 CDC42SE2 GRAMD1A MAP4K2 JPT1 RBM5 ATPIF1 TUT4 HNRNPA3 RIPOR2 KMT2D CHD3 SWAP70 H2-EB1 HNRNPU H2-Q4 DBNL H2-Q6 SLFN2 HBA-A2 MNDAL TRIM12A SNX5 HBA-A1 H2-T24 DOCK10 TRIM34A BC005537 BAZ1B EIF2S3X GIMAP6 9930111J21RIK2 XRN2 PNRC2 IFI203 SCD1 ETNK1 H2-Q5 PSME2B H2-M3 PRKCB GRAP DGKA ZFP740 BAZ2A DDX6 FCER2A 1-SEP ZFP207 FGFR1OP2 OGA GDI1 GM16286 PRRC2A H2-DMB2 GM21738 EIF5 MAN1A ARPC5L DGKD PKN1 FCHSD2 FAM120A CCDC88C GPBP1L1 CD24A TMEM131L FTL1 PLEKHA2 ESYT1 WDR26 SIGLECG H2-DMB1 GIMAP3 SF3B2 TRIR SBF1 SH3BP5 GM10801 CCL21A RNF10 APOBEC3 LUC7L2 500 genes up-regulated by SARS-CoV-2 (0.2 MOI) in human A549 cells transduced with ACE2 vector from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/3HGCcXglY CEP350 RSRC2 GDF15 CCL2 EGR1 TRIM59 TNF CXCL5 TBK1 RCHY1 MAST4 NGDN PLEKHF2 HLA-B BRAF ZBTB7B CD200R1 NFKB1 SNIP1 GPR142 STAT1 PDE4D SDE2 BRD4 FRMD4B CXCL2 ING3 USP15 ZNF503 ARL14 CHD1 MYNN ZCCHC3 ZC3H12C H2AFJ RBM39 FZD5 NXT2 MCL1 CP CXCL1 ASS1 CEBPD KLF5 HES1 DUSP16 PARD6B NFAT5 PNRC1 MARCKS EVA1C TET2 GADD45A HIST1H2AC MALAT1 BDP1 SIX4 MDM2 ARHGAP30 SDC4 ZBTB43 ERI2 DDIT4 ELL2 ASPM H1FX H1F0 UAP1L1 ICAM5 PER3 TOPORS CHIC1 ZNF830 PTGS2 ZNF184 ZNF195 KLF10 CNOT6 GADD45B SRSF1 EVPL ZNF217 EREG DLX2 ATF3 PNN MAFK SLC45A4 BCL3 CEBPB SLC12A7 TAB3 FBRS ERF CFB CCL20 KIF20B SELE LACC1 HLA-F C3 CXCL3 C1R FGG SOCS3 NFKBIE NAMPT ARC NFIL3 PIM1 MITD1 FST ZNF711 RIMKLB DBP BTG2 SPTSSA ZFP36 LAMTOR3 IER2 IER3 FOS IRF1 TGM2 ICAM1 NFKBIA ID3 IRF9 JUNB JUN CA2 BTG1 PRX C11ORF96 JUND ARRDC3 TP53INP1 SP3 EFNB1 PLEKHG2 PIM3 CCNL1 CTDSP2 GEM ESF1 KDM6B POU2F2 ZC3H12A DDIT3 DUSP8 AOC3 FGB EGR2 NR4A3 PPP1R15A CSF1 GPRIN3 B3GNT5 ZNF436 DCUN1D3 TNFAIP3 ZNF484 HDAC9 IL23A NTNG2 ZNF267 ZNF596 ZFP37 ZNF292 FBXL19-AS1 BCORL1 BBC3 PPP1R15B NEURL3 IER5L IER5 TIPARP YOD1 IRF2BPL CSRNP1 ZSWIM6 BHLHE40 TAF1D MAFF NFKBIZ TSC22D2 SERTAD2 SNHG1 KANSL1 FOSB ZBTB34 MSL2 DEPDC7 RAB2B PPP1R18 TAF13 NOC3L C3ORF38 RLF MXD1 ZNF317 USPL1 INTS6 ODC1 GPBP1 TOB1 PDE4B ARGLU1 TTC32 NEAT1 ID1 EFNA1 TSPYL4 PURB SETD2 EID2B CREBRF HIVEP2 YTHDF2 ZNF337 SRSF6 UHMK1 NECAP1 ZNF211 FOXC2 REL ABL2 NNMT TOR1AIP2 PDK4 RASD1 MAP3K8 HIST1H4E PRPF39 SCARNA15 LINC00472 PER1 CFI ZBTB6 BCL10 ANKRD49 ZRANB2 UFM1 CCNT1 CRKL FEM1C YTHDF3 IGFBP1 FNIP1 ANKRD12 ZNF567 TGS1 PPP1R10 HSD17B7P2 RSF1 RFX7 FOXC1 CD83 RELB CPEB2 CLUHP3 PMAIP1 TICAM1 ARL5B ACHE SMCHD1 C1S THAP9-AS1 HMGN2 RAP2B CDKN1B RNF6 LTB DYRK1A THAP2 PPTC7 CHST2 CLK1 GRPEL2 PIGA HIST2H2BF NR4A1 LINC00641 NR1D1 LOC284454 SPRY4 ETV3 SIAH1 THUMPD1 MDM4 SPRY1 PPARGC1A SIM2 RNF11 NFKB2 TNFAIP8 CYLD SNRNP27 TIGD1 AP5Z1 BHLHE41 C6ORF62 ZC3H11A ZNF324 USP36 FLCN ZNF8 ZBTB10 SNAP25 GPCPD1 RBBP6 PTP4A1 ZNF430 WDR43 CCNT2 ZNF518B FGA TET3 MIER1 HIST2H2BE LBP CCDC71L NFKBID SNORA48 SERTAD3 EPC1 HBP1 MBIP ZNF451 MEX3C ACBD3 VAMP2 ZBED5 KDM6A JMJD1C SUZ12 SMC4 YAF2 THUMPD2 ZBTB21 CHD2 SLC12A6 RBPJ FOXA2 CRTC2 FBXW7 UBR5 APAF1 SLC30A1 PPM1D RAB24 ZNF12 ZNF627 VCPIP1 RBAK ZKSCAN8 POU2F1 DMTF1 CCNG1 PRPF38A ZCCHC10 ZNF639 UTP15 ZBTB5 TEF MAP3K9 ZNF24 NFKBIB USP42 ZC3H4 ZNF764 SCAF4 YY1AP1 THAP1 MED1 MED26 ARID2 CNOT4 ZBTB11 WTAP ZBTB48 ZNF77 INO80 BRPF1 AEN SRFBP1 SKIL CLK4 HIVEP1 MIER3 MYSM1 PGAP1 PHIP AEBP2 WRAP53 CACTIN SNHG10 SAMD11 FRS2 ADNP2 PAXBP1 MED13 DIDO1 TRMT10C VEZF1 ZBTB1 SOCS5 GPATCH8 PCF11 STRN3 ARMCX5 FOXN2 TUG1 ZNF654 IRGQ ZNF805 ADM5 ARID4B TLK2 TGIF2 CPEB4 SNORA63 CELF1 SLC7A2 PNRC2 FGFR1OP2 GPBP1L1 WDR26 ZFC3H1 HIST1H2AK BRE-AS1 CHIC2 PLD6 MIR3191 SOCS4 ZNF281 GRHL1 FAM126B HIF1A-AS2 EDA2R ZNF121 CEP85L HNRNPH3 RBM12B MIR5047 NBEAP1 COL2A1 ATAD2B PRKXP1 DR1 SIN3A ZNF776 ZNF614 CEP95 PRR14 ZNF557 ZNF845 SMNDC1 KIAA2026 CHD9 ZNF79 RBM48 IKZF5 TYW5 STRIP2 ZNF92 EPM2AIP1 USP37 ZNF57 B3GALNT2 HIST3H2A ZNF770 INO80D CARD9 MAPK8IP2 EXOC8 RASSF8 RASSF9 SNX16 TCTE3 LYSMD3 LOC644656 C5ORF51 LINC00115 ICOSLG MED9 RLIM ACAN FOXD3 IRF2BP2 SNORA28 ARMCX3 HIST1H2AI HOXA3 EAF1 ZNF555 KIAA1586 HCFC2 RMRP CDK5R1 500 genes down-regulated by SARS-CoV-2 (0.2 MOI) in human A549 cells transduced with ACE2 vector from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/3HGCcXglY MYH9 UBB JAK1 UBL5 AP2A2 RTN4 EEF1A1 ERMP1 DPP4 FKBP1A PIGS COL6A1 ATP6AP1 GHITM SPTAN1 ERGIC1 EPB41L2 SUN2 ETFA PRKACA CAPN2 PPP2R1A CDH17 LMAN2 SLC9A3R1 TSPO COL4A6 NPC2 EPB41L1 EZR ANXA3 VIL1 MIPEP PKM COL4A1 ANXA2 NDRG1 TUBB4B ADAM9 DYNC1H1 UBA1 AP2M1 TUBA1A PITRM1 ANXA11 FAM162A SERPINE1 TCN2 PSMD4 GGCX COL4A2 CTSD TUBA4A ACADVL SFN MFGE8 CNDP2 FBN1 PLD3 ALG8 PHB NEDD8 PXN MSN KRT20 PLS3 ANO6 APP FCGBP PLP2 MDH1 PSMB1 ADH5 TLN1 RNF167 CAV1 ENO1 OCIAD2 RPS26 CEACAM6 FAM114A1 KRT7 NEBL DDAH1 UQCR10 KRT4 NT5E UPK1B NDUFB2 DSG2 GALNT5 C1ORF116 BCAS1 COX6A1 KRT19 KRT15 PRSS23 GPRC5A AGR2 CCND1 TMEM109 TAGLN2 OGDH ANKRD52 PYGB ATP1A1 TMBIM6 SLCO2B1 BANF1 PDIA6 UQCRC1 THBS1 PRKCSH ACSS1 GSN FLNA CD81 CYBA LRP1 LMNA UNC13D PLOD1 NDST1 EDEM2 GANAB EFTUD2 EMP3 TMED9 NRP2 SLC6A6 ABHD2 ACLY SYNGR2 SLC38A10 ZYX MYOF DHCR24 TK1 ALDH1L2 ANXA2P2 ALCAM LGALS1 FUCA2 CAPNS1 ITSN1 PRDX1 MPDU1 LAMC1 GSTO1 G6PC3 RPL26L1 NME1 OLFML2A ACO2 MICU1 PSMB2 PRDX3 SPATS2L TPI1 LIPA SORT1 ALDH4A1 SCD PSMB7 COL18A1 CTNNA1 ZNF185 COL5A2 SERPINH1 TGFBR2 APLP2 AXL ACTB HMGA1 CGN SREBF1 AP1M2 LAMB3 CAPN1 JUP PLCD3 TRIM16 KRT80 GIPC1 MST1R CLU WNT9A ARHGAP1 CD63 BMP1 SORL1 MBOAT7 KRT86 GATM GLIPR1 COTL1 ALDH1B1 AMBP IGFBP6 VCAN TRAFD1 GFPT2 WARS EPHX1 CD59 DDC PFN1 LASP1 CNN2 YBX1 CYTH3 TUBA1B RASGRP3 PEBP1 HMGCS1 CAPZB ATP6V0E1 CDC42EP1 GSTP1 RPS19 BCAP31 MDH2 SNRPD2 ACAT2 EIF3K NDUFA13 TAGLN PSMB6 EIF5A PPP1CA DRAP1 PSMB5 S100A6 SH3BGRL3 RPL18 VIM SRP14 RPS9 OAZ1 NDUFA2 EMC3 PRMT2 CALR PSAP S100A16 KLHDC3 CFL1 TUBB2A IGFBP7 EHD1 MYLK LBH ANXA1 GNS FASN NDUFA4 NOP10 MYO18A FSCN1 VCL S100A10 DAD1 ANK1 TMEM14B S100A3 GPX3 MAGT1 PRR13 TM4SF4 MRPL24 ATP6V1E1 S100A11 MRPL27 NFU1 PSMB3 DPP3 AHCY UQCRQ CORO1C TIMP2 CAP1 LDOC1 LAMB1 AKR1B1 RPN2 NDUFA9 SF3B5 ETFB LDHB ATP2C1 RUVBL2 NUDC GFM2 ANKRD1 MAP1B AKR1B10 INSIG1 MSMO1 GALNT18 CSRP1 MVD SLIRP SLC1A4 ACTN4 CST1 LMAN2L AARS TRNP1 FAM171A1 LAMB2 UCN2 GLG1 LIPH LAMC2 GLP2R LIMA1 CEACAM1 GPT2 OXTR VAT1 PROCR NCEH1 SH3KBP1 TM7SF2 ALDOA RSU1 ACTN1 MYL6 BLVRB ILK CDA CD44 GRAMD1B LPIN1 FADS2 DNM1 LOXL2 LAMA3 CD68 ITGA6 PGK1 PEF1 SDHA TRAPPC1 EXOSC1 ACTR1A PET100 TBXAS1 BSG GNAS OTUB2 CPPED1 USP5 APMAP CD82 PRKCA HM13 TMEM43 MCFD2 TPM1 NXN COPS6 AHNAK BECN1 ABHD12 ACAA2 COA3 ABHD4 TPCN1 NUBP2 ATP8B1 CDH4 RAP1GAP PAPLN PRKAR1B PINK1 ADI1 PCDHAC1 MATN2 ASNA1 FLII LSS ADCY5 G6PD CYSTM1 RTN3 ENTPD6 MAP4 AMOTL1 DKK3 PLXNA2 ABR NES CTTN PSMD2 FDPS TUBB4A ITGA3 FDFT1 SMARCA2 IL6R ADD1 LIPC LRPAP1 CPM SREBF2 CPA4 ECE1 ELAC2 ACACA PTPRF TSPAN15 TXNRD1 P4HA2 GSR GPC1 MYO1C PRKDC SCARA3 LTBP1 PARP4 CYP51A1 SLC16A2 PEA15 TNC WDR4 RPS4X ACOX3 TMEM59 RHOC TPD52L2 MGST3 NSFL1C KRT81 FLNB ANXA9 EHD2 DARS2 SLC41A3 PFKFB4 PSG4 NRCAM DHCR7 NSDHL EBP RPA1 MICAL2 ANXA6 NDUFB8 KLHL4 CPE GPD1L TECR NOC4L MYRF SVIL NDUFS8 SPNS2 ECH1 IDH3G ANKRD10 DNHD1 PFKP KIAA0754 HSPG2 MAPRE2 NIPAL3 CACNG4 EIF6 PCCB ECI2 DOCK10 NRSN2 MICALL1 TRIM45 HSPA12A LOC100129034 NID2 FRAS1 PHKB MAMLD1 CTC1 ADCY9 CCDC127 SND1 ANO10 PPME1 PDLIM7 RAB3B AP2B1 DAG1 CAP2 MRPS18A PSG5 DPYSL5 PTPRN2 STK32B GPR39 CST2 TDRKH 500 genes up-regulated by SARS-CoV-2 (2 MOI) in human A549 cells transduced with ACE2 vector from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/tFNTPbzwo NKX3-1 CEP350 RSRC2 FAM8A1 BIRC3 IL6 GDF15 CCL2 EGR1 VDR PTBP2 DDX58 TBK1 IL1A IFITM1 PLEKHF2 HLA-B KLF6 CD200R1 NPTX1 NFKB1 SNIP1 OAS1 BIRC2 TRIM25 OASL SMARCA4 CXCL2 IFNB1 USP15 FERMT3 ISG15 ARL14 MX1 MYNN ZCCHC3 ZC3H12C RBM39 CD55 BCL2A1 MCL1 ARL4D CXCL1 IFI27 HES1 DUSP16 ZEB2 NFAT5 PNRC1 RICTOR TET2 GADD45A ANKRD33B PRDM1 MALAT1 SIX4 ISG20 ZNF462 NEDD4L TAB2 PARP10 SDC4 ZBTB43 IFI44 MAFG BATF2 NRIP1 ICAM5 PER3 ZNF830 PTGS2 CRY1 ZFP36L1 KLF10 KLF11 SEMA4B IL20RB EREG SOX9 NAV2 ATF3 MSX2 PNN TCF7L2 STK40 BCL3 CEBPB SLC12A7 HELZ2 OGFR OAS3 IRF7 NLRC5 TNFRSF9 CCL20 IFIT1 SELE IFIT3 HLA-F CXCL3 CD274 APOL6 USP18 CMPK2 IFIT2 IFI16 CLEC4E NAV3 IFIH1 STAT2 PML SOCS3 NFKBIE PARP9 PARP12 ARC SAMD9L NFIL3 PIM1 INHBA PARP14 FOSL1 SOCS1 MITD1 SP110 DBP IRF2 BTG2 KLF4 ZFP36 LAMTOR3 IER2 IER3 FOS IRF1 DUSP1 TGM2 ICAM1 NFKBIA JUNB JUN BTG1 PRX ARRDC3 PLEKHG2 ATF4 PIM3 CCNL1 THEMIS2 PHLDA1 GTF2B YTHDC1 CTDSP2 GEM ESF1 KDM6B POU2F2 CREB5 ZC3H12A DDIT3 DUSP8 TRAF1 RAB30 PPP1R15A B3GNT5 ZNF436 TNFAIP3 ZNF484 ZNF267 ZNF292 FILIP1L SNHG15 CDKN2AIP BBC3 PPP1R15B LIF IER5 TIPARP YOD1 CSRNP1 BHLHE40 TAF1D MAFF NFKBIZ SERTAD2 ZNFX1 SNHG1 KANSL1 IL11 FOSB MSL2 NOC3L HSF2 PNPT1 C3ORF38 RB1CC1 RLF MXD1 ZNF317 USPL1 INTS6 ODC1 GPBP1 DUSP10 PDE4B KLF7 NEAT1 EFNA1 PURB CREBRF SALL1 SCAF8 HIVEP2 ZNF337 USP43 RND1 NECAP1 ZNF211 SFSWAP ZBTB2 EFNA3 FOXC2 REL ABL2 PSD3 PPM1K ZCCHC2 TRIM21 TDRD7 MAP3K8 MORC3 IRAK2 HIST1H4E IFI6 PRPF38B LINC00472 PER1 DRD1 DDX60 SLC25A28 RNF19B C19ORF66 XRN1 SP100 BCL10 IFIT5 HERC5 TRANK1 RPL22L1 ANKRD49 DDX60L SAMD9 SNHG12 CCNT1 CRKL MB21D2 FNIP1 ANKRD12 ZNF567 PNISR PPP1R10 RSF1 CD83 ETS2 WEE1 C3ORF35 HDX RELB CLUHP3 TICAM1 ARL5B PATL1 C5ORF56 SMCHD1 THAP9-AS1 TRIM38 RAP2B CASP8 CDKN1B RNF6 LTB SON NBPF10 PPTC7 HOTAIRM1 CLK1 ZNF674-AS1 PIGA HIST2H2BF NR4A1 LINC00641 PLSCR1 NR1D1 LOC284454 ETV3 BDKRB2 TANK CSTF3 UBE2B APOBEC3F MDM4 NFKB2 TNFAIP8 ELL ZNRD1 CYTH1 OTUD1 CYLD SMURF1 ZNF34 ANKRD18A C12ORF50 BHLHE41 CHMP1B ZC3H11A IP6K2 USP36 PHC3 FLCN ZNF14 ZBTB10 NSRP1 GPCPD1 RBBP6 REC8 DNTTIP2 CBWD2 CCNT2 SUZ12P1 TET3 NIPAL4 RNF185 PDRG1 REPIN1 MIER1 HIST2H2BE EIF1B NFKBID SERTAD3 EPC1 MOAP1 HBP1 ZNF160 VPS37B SPHK1 MEX3C NFE2L2 SPOCK2 VAMP2 PER2 COL4A3BP KDM6A SENP7 JMJD1C ASXL1 SETD5 THUMPD2 ZBTB21 CHD2 RBPJ CRTC2 FBXW7 TSC1 PPM1D ZNF12 ZNF627 ZSCAN12 RBAK ZNF641 NRBF2 TBC1D15 GTPBP1 UBXN7 ZBTB17 SETX POU2F1 DMTF1 UTP3 ZNF639 UTP15 PPIL4 PRDM4 CASP10 ZNF24 NFKBIB USP42 POGZ DIP2C ZC3H4 ZNF764 SCAF4 TBC1D22B YY1AP1 THAP1 RBM33 MED1 MED26 CNOT4 WTAP ARID3B DCP1A ZNF77 ITSN2 AEN ABTB2 SRFBP1 ELMSAN1 SKIL CLK4 HIVEP1 MYSM1 AEBP2 MCTP1 KDM5B IFRD1 DNAH17 WRAP53 SNHG10 FRS2 ADNP2 MED13 DIDO1 RBM15 KAT6A VEZF1 ZNF7 ALOXE3 ZNF778 GPATCH8 PPP4R1L CCDC174 PCF11 CWC25 FOXN2 C11ORF68 ZNF654 ZNF805 ADM5 ARID4B PPP4R4 TLK2 CPEB4 CELF1 GPBP1L1 ZFC3H1 HIST1H2AK BRE-AS1 CHIC2 PLD6 ZNF281 GRHL1 HNRNPH3 MIR5047 COL2A1 PRKXP1 PRR14 ZNF79 RBM48 IKZF5 EPM2AIP1 USP37 ZNF57 B3GALNT2 INO80D RASSF8 LOC644656 C5ORF51 LINC00115 MED9 RLIM ARMCX3 EAF1 ZNF555 HCFC2 THAP3 MRPL44 DIRAS1 P2RX5-TAX1BP3 GZF1 EZH1 ZNF143 CLASRP OTUD3 PPP4R2 NRG4 ZNF107 ZRSR2 GOLGA7B HIC2 SFMBT2 DNAJC27 PIBF1 FOXJ3 GUCA1B MSL1 ZNF721 LOC648987 SLC9A8 ZIC5 BTN2A1 500 genes down-regulated by SARS-CoV-2 (2 MOI) in human A549 cells transduced with ACE2 vector from GSE147507 SARS-CoV-2 infection of human A549 cells Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/tFNTPbzwo GOT1 NUP210 DCTPP1 UBL5 EMC1 TARS2 EEF1A1 ERMP1 UHRF1 FKBP1A CAPN5 ATP6AP1 HYOU1 GHITM VCP YWHAQ CISD3 CDH17 LMAN2 SLC9A3R1 SWI5 PPT1 CYB5B ATP6AP2 TMEM97 PFKL SCCPDH ANXA2 ADAM9 GPAA1 SIGMAR1 AP2M1 F5 TUBA1A MRPS27 ANXA11 GPX1 CALM1 COL4A2 CTSD PABPC4 TST CANX ABCG2 MFGE8 REEP5 PLD3 ALG8 PCSK6 PEPD PHB EXOSC5 STOM PLS3 HS2ST1 CAT PTGES2 MDH1 TRAP1 TM7SF3 SCP2 COX15 BPNT1 FAHD1 WDR34 SIAE NDUFV1 GSTZ1 FECH ENO1 TBCB LAS1L NDUFA10 RPS26 PARVA SDC1 NT5DC2 KRT4 SLC40A1 GPX2 TSPAN6 NDUFB2 CNN3 DSG2 COX6A1 RPS15 PRSS23 AGR2 FTL CD24 TSPAN3 SMARCD2 ATP1A1 SLCO2B1 BANF1 PRPS1 PDIA6 DDOST PRKCSH PGD CHID1 FLNA EMC10 FKBP8 CYBA CORO1B PLOD1 SLC16A3 GANAB EFTUD2 TKT PDIA4 TMED9 SYNGR2 PYCR1 DHCR24 DHRS4 TK1 MRPL12 C5 CREG1 HSD17B4 ADAM15 SPR ANXA2P2 NDUFS7 ALCAM LGALS1 SLC39A11 FH HADHB NDUFAF3 CAPNS1 RRM2 SHMT1 BCAT1 PRDX1 MPDU1 TP53I3 G6PC3 NME1 OLFML2A IDH1 ACO2 GRHPR PRDX3 TPI1 SORT1 ALDH4A1 SCD SGCD PDGFD CRIP2 AKR1C3 COL18A1 PBXIP1 LLGL2 SERPINH1 PKD2 CKS1B TGFBR2 APLP2 AP1M2 CAPN1 JUP GIPC1 TPD52L1 KITLG CLU SFRP4 LAMP1 PREB PITPNM1 GATM MCM5 PSAT1 ALDH1B1 AMBP IGFBP6 VCAN SLC7A11 EPHX1 PCOLCE2 TTYH3 PFN1 YBX1 TUBA1B AKR1A1 PEBP1 CAPZB TXN TPPP3 ATP6V0E1 GSTP1 TSPAN7 SH3BGRL FABP5 COX7A2L BCAP31 CRIP1 MDH2 ITM2C SNRPD2 ALDH1A1 EIF3K NDUFA13 PSMB6 COX8A PRDX5 PSMB5 NDUFS6 SLC12A2 CETN2 RPL18 PDCD4 RPS9 TOMM20 HADH OAZ1 PRPF19 STUB1 NDUFA2 SOD1 TALDO1 CALR PSAP KLHDC3 MXD4 COX6B1 IGFBP7 MYLK PSKH1 VDAC3 ANXA1 TMED10 FASN NDUFA4 PDCL3 ANAPC5 FSCN1 OAT S100A10 ACADSB SERINC3 CNTN1 PGRMC1 NDUFB10 TMED2 COX14 APOH SERPINI1 TMEM14B CYP4F3 DPY30 ANP32A OST4 ATRAID PRR13 TM4SF4 POLR2G NQO1 MRPL24 CDC123 LAMTOR2 EMC4 ATP6V0E2 OXA1L NDUFAB1 CRYZ EPDR1 POLD2 RNASEH2A PRDX4 CKB SLC25A11 C12ORF57 PSMB3 AHCY NHP2 EBNA1BP2 TMEM14A TMEM230 ATIC UQCRQ TSPAN4 POLR2E POLR2J SSR4 PTDSS1 PSMA7 UQCRH CCT7 PPP3CA RUVBL1 GTF3C6 AKR1B1 RPN2 SEC23A ETFB LDHB SERINC5 GLB1 TNFSF15 AKR1B10 ZMPSTE24 SLIRP DNASE2 ACTN4 ALDH3A1 LMAN2L AARS TRNP1 CYP4F11 THSD7A SUMF1 SEMA3E TFPI2 MRPS11 MLEC GLG1 SLC47A1 PCYOX1 UCP2 PAPSS2 TTC8 NEFL GALM TM7SF2 RSU1 MSRB1 RNH1 ADAM10 CD44 FLRT2 LANCL2 INSL4 FADS2 ADAM12 MMP24 PGK1 ANAPC11 SAMM50 PET100 UCHL1 BSG F2RL2 QARS MRPS12 GBA USP5 APMAP PLBD2 PSMC5 PHGDH ALG3 SPP1 TMEM43 GALNT1 NNT MCFD2 PNPO CMAS ALDH3A2 ASAH1 AURKAIP1 COPS6 C19ORF53 APRT BECN1 ABHD12 ALDH3B1 ACAA2 CNPY2 COA3 GGCT MANSC1 SLC25A10 MPST TPCN1 HLTF RAP1GAP ADI1 MATN2 ASNA1 P4HTM TRAPPC6A POLE4 FASTK CPLX2 G6PD RTN3 C19ORF48 NOC2L NDUFA11 TBCD FDPS TUBB4A TCTN3 UNC45A FDFT1 LRPAP1 GCLC CPA4 SEMA4G GOLM1 INHBB TXNRD1 GSR PGP NOTCH3 GPC1 EIF4EBP1 TMEM106B DNM2 MTHFD1 EXOC4 RANBP1 CALU TFDP1 PIN1 THOC3 LSM4 HNRNPAB MRPS34 LAPTM4B RPS4X TMEM59 TMEM14C SLC48A1 ANTXR1 MGST3 PDHA1 MRPL23 ASPH TPGS2 DARS2 ALDH7A1 POLR2L CDKN2AIPNL MAGED2 SRPRB NRCAM COMMD4 GPS1 NSDHL MMAB TMEM141 TRAPPC2L EBP RPA1 ANXA6 ZP3 NDUFB8 KLHL4 DSC3 SULF2 QPCT GPD1L IGFBPL1 HSPBP1 FAM217B WDR18 NDUFS8 RPUSD3 ECH1 FARSA PHYH HSPG2 MAPRE2 NIPAL3 ERLIN2 CD99L2 TCTN1 EIF6 PCCB IQGAP2 PHKB SND1 PPME1 DAG1 CAP2 DPYSL5 SVEP1 MPI MRPS16 VPS33A DCDC2 TM4SF18 TNPO1 MBTPS2 SMPDL3B SERBP1 EML1 PHPT1 SGCB HEATR5A PIGX AGA GIT1 SAMD5 392 genes up-regulated by SARS-CoV-2 in ferret nasal wash from GSE147507 SARS-CoV-2 infection of ferret nasal wash Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/AdAvSOVkM FCGRT CCL2 CCL5 HYOU1 VDR EPB41L2 CXCL10 PPT1 NGDN PFKL COLGALT1 RASA3 TPRN ASPSCR1 IFNG PITRM1 TREM2 SERPINE1 BCS1L PMPCA GGCX RAD23A MRPS25 EPB41L3 PLD3 PCNT PEPD OASL NUP88 SMARCA4 PES1 SHARPIN NUP85 SRC MX1 ATAD3A GADD45GIP1 NAT9 CPT1A SERPING1 TNFSF10 RPLP2 EXT1 METTL23 SNORD17 FNIP2 RGL1 CCL8 ISG20 C1QC PIEZO1 PDCD11 SH3TC1 DPP7 EMILIN2 CD81 LRP1 LMNA EIF3B INF2 SLAMF8 TKT PDIA4 CLUH EMP3 NRP2 FBXO6 GALNS NLRP1 CCT5 GLMP TIMP1 EZH2 SCARB2 MYO1E PSEN2 ADAP2 NDUFS7 MSR1 AP2S1 LGALS1 ANXA5 GPNMB SHMT1 ITSN1 CTSZ MAFB C1QB MPND CD163 UAP1L1 GALK1 NME1 MERTK FAM20C BATF2 SNX8 SH3PXD2B CD247 U1 SH2D2A MATK MYH11 ANGPTL6 GATA3 SLC30A4 SERHL2 PIK3IP1 MPEG1 BATF MROH1 WDR7 SLC4A2 ABI3BP LRP5 IRF8 ZCWPW1 PHC2 ZAP70 GRAP2 QPRT NKG7 AOAH IL18BP CTSW CD5 IL2RB GZMA TOX PTPRCAP CD72 GPR31 SLAMF9 TNIP3 CD3E CCR5 CD2 LY86 KCNN4 LAG3 PTPN7 CD86 SIGLEC1 CYBB PLA2G5 LGMN ARSI PTGES GBP6 IL4I1 INHBA SLC39A14 FOSL1 SOCS1 SAMHD1 GLT8D2 SLC7A10 C1ORF56 TTYH3 PLTP PSMB10 CTBP1 HPCAL1 LIMCH1 RPN1 ARL6IP4 C1QBP BNIP3 KRTCAP2 CRELD2 DHX30 HSPH1 TRMT112 TNS3 TCF4 NRP1 NUCKS1 GLRX5 TRIM46 CCDC85B ESF1 MAP4K1 BPI SORBS3 IER5L IRF2BPL TSC22D2 DPM3 PSMD1 WDR77 CUTA MIF STIP1 NHP2 SEH1L UQCRQ HDAC1 TUBB6 TUFM MAD2L2 TSEN34 SDF2L1 FKBP4 MRPS6 TIFAB BTBD6 APBA3 VAMP5 PRF1 AVIL BATF3 WDFY4 RGS10 MAP1S TRPM5 METRNL RFC2 TAF3 EIF5B SMC5 VAT1 ACHE CCR7 GZMB NAV1 SIRT4 CHST2 CHKA OLFM1 CRLF2 GZMH TMEM214 CGAS DOT1L NFATC1 MMP14 TXNDC5 TXN2 XPNPEP1 PLBD2 DDX56 AP5Z1 AHNAK ATP5ME C11ORF71 TBC1D17 MPST PARM1 RIN2 NPAS1 SPNS1 TEP1 VPS18 LRP3 CHGA PACS2 TTLL12 MFSD12 DDX39A ANKRD22 JAK3 SYN1 PLXND1 NOP56 TSR1 NOC2L GNL1 TBCD TSSC4 SIVA1 AFG3L2 SPHK1 ATP8B2 PUM3 TMEM79 ZFHX3 LRPAP1 ECE1 PLXNA1 SSRP1 TMPRSS9 BACE2 P4HA2 DDX27 PITPNM2 HSF1 DRAM2 FAM133B MAP1A ATP13A2 HK2 CD79A NR1H3 AEBP1 GUSB MESD NAA15 RRBP1 ALDH1A2 ILKAP MYBBP1A CCDC137 MRPS34 NOP53 PLOD3 DNASE1L1 ENO3 FLNB RTF1 ARHGAP17 FSTL3 EIF2B1 REV3L CCDC50 DNAH17 TECR WRAP53 CABLES2 INTS1 TMEM104 HSPBP1 RAD9A LNX2 WDR18 MRPL55 PDLIM4 MED16 LONP1 TRIO PDE8A ZNF516 RIPOR3 DOCK7 LRCH1 CHD3 DERL2 APBB1 H2AW PALM3 STRIP2 CARD9 SND1 FBXL15 FAN1 UBXN11 U3 SNORD15 CAMK2B REXO5 RNASEP_NUC ATP5F1D KCNK7 LSM14B SNORD22 ST6GALNAC4 RRNAD1 RDH5 5S_RRNA 7SK SLC25A48 DNAJC1 LOC101673948 RBM19 TVP23A TELOMERASE-VERT LOC101686332 TULP2 MLLT6 TBRG4 USP35 NAXE CLEC10A MED20 SLC66A1 PCDH19 P2RX7 FMNL3 HDGFL2 CIZ1 RNASE_MRP PHYKPL IDUA SLC12A4 MSTO1 C1ORF35 C19ORF44 BRSK1 SNORA73 DOCK4 420 genes down-regulated by SARS-CoV-2 in ferret nasal wash from GSE147507 SARS-CoV-2 infection of ferret nasal wash Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/AdAvSOVkM PPBP MAPK3 ENDOU EGR1 TMPRSS2 GMIP MALL IL1A SLC26A6 EPB41L1 TMPRSS4 GABARAPL2 SDCBP2 ACSL3 F5 ANXA11 USP2 CRISP3 MPZL3 SULT1B1 TMPRSS11D ST6GALNAC1 MGAM PLS3 CAT HERPUD2 AGPAT2 TMPRSS13 DPH5 GGH MAPK1 PGM2 NR3C1 CREBL2 TPMT MTMR14 BPNT1 GBE1 MYO6 FBXL3 ALDH1A3 DEDD2 CYP2F1 TMC5 TFF3 TMEM71 PERP ATP12A KLF5 RGS2 RBPMS KRT4 CGNL1 ECM1 AQP5 FAM117B DUOX2 ELF3 PPL LMO7 C6ORF132 SCEL WFDC2 SERPINB2 HSPB8 TCP11L2 C1ORF116 STEAP4 FAM214A SLC2A1 GADD45A SLPI TJP1 SPINK5 CD300E EXPH5 GPRC5A S100A2 ESRP1 TMPRSS11E CRNN EHF MYO5C MAP7 PLEKHS1 MAL2 MPZL2 PRNP THBS1 PLCB2 CD37 MYADM ABHD2 ZYX CD101 MACC1 SLC35A5 AREG HVCN1 SERPINB10 METTL9 TNFAIP8L2 DPYD IDH1 NRIP1 CXCL8 SH2D1B PTGS2 TUFT1 RMND5A IL18RAP MMP1 CDH1 B4GALT4 PLAUR SPINT1 OSM LTF USP32 PROSER2 JUP SERINC2 RARG KRT80 MYH14 IRF6 RHOD WLS MEF2C SLC5A8 MMP8 GABARAPL1 HNRNPH2 RGS3 TMEM164 ST6GALNAC2 WDTC1 ACPP SOAT2 HCLS1 MEFV CD48 RINL AGAP2 TNFSF14 MS4A7 CLEC5A ARHGDIB RAC2 HMGB2 MYO1F BPIFA1 MOGAT1 IL1R2 PTAFR CYP4F8 TREM1 XDH SELP F3 CSTA BTG2 CYP4B1 EPAS1 FOS SGK1 MYL12B DUSP1 TXNIP HPGD ITM2B DAZAP2 BTG1 SERPINE2 ALDH1A1 NR1D2 SLC12A2 PAIP2 NDFIP1 HADH TYROBP S100A16 CYP2B6 STK38 ANXA1 RNASE6 IVNS1ABP RAB5A CD9 MYZAP SAMSN1 RGS14 PADI4 PENK S100A12 PGLYRP1 LRRK2 GJA4 MUC1 CHAC1 NFKBIZ CDC42EP3 SLC25A33 TSPAN31 WBP2 SLC29A1 YPEL5 ARFIP1 GSKIP HSD17B2 CAP1 DHX40 HDHD2 TAX1BP3 MXI1 ARG2 AFTPH GRHL3 TOB1 KLF7 CNFN FOXO4 SRI TAF7 KLHL24 FAM110A CREM SELL RIPK2 DGAT2 TMEM40 NFE2 BIN2 LBR VMO1 CPNE2 CASS4 CTSV CAPN14 PELI2 RP2 ANKRA2 CRISPLD2 ADRB2 CASP7 LIPH CYSRT1 CHUK SLC28A3 PARP8 BPGM BTC IL18R1 PHACTR4 PTGS1 R3HDM4 CDA SF3B1 SARAF CALM2 CAST ADD3 EVI2B PRKAG2 DAPK2 ENTPD1 CXCL14 ADAM19 RNF144A FCHSD1 RASGRP4 TLR8 IFNGR1 POT1 TSG101 UBE2B DOK3 HHEX CXCR4 HTATIP2 GDE1 STK10 RNF13 RFK IRAK3 ATP1B3 CCPG1 ABHD5 ATP8B1 RCBTB2 TSPAN1 AHCTF1 GPCPD1 ARHGAP24 PPP2R2A MAP3K3 YPEL3 PROK2 RGS18 FHL3 NFKBID TMEM154 ATP6V0A1 HBP1 KAT5 LMBR1L UCK2 PCDH1 ARAP3 SLC52A3 FAM3D CST6 CPNE3 AMPD3 SPOCK2 BMX STK38L TRIM24 RAB27A ADGRE3 SPINK7 MUC4 ABCC10 CCNG2 PRKAA1 FBXO32 PAK1 PPM1D STRADA CD300LB SLCO3A1 IMPDH1 SLCO4C1 SEC14L4 MET RASSF2 MCMBP GRK6 RCSD1 JAML SH2D3C TMEM59 CSGALNACT2 CYB5R4 KRT23 ASPH ANXA9 HECA ADGRF1 SEL1L3 NECTIN4 RNF146 TIAM2 ARHGEF28 CLK4 RAB11FIP1 NCCRP1 FAM49A LRMP CPD TOM1L1 QPCT KCNK5 PHACTR2 EMB DCAF11 BAZ2B PADI1 HECW2 DOCK5 RIPOR2 TUT7 RESF1 MFSD14A ST3GAL2 EHD3 ARHGAP15 MSL1 PIGX PLCL2 B3GALT2 PIGV LSM10 UBXN2B ABHD17B DUSP14 CCNDBP1 DCAF12 KLHL2 PITHD1 CCNJL SPRTN LOC101680039 PDCL RELL1 BTBD10 RAB38 LOC101686805 BIN3 RUBCNL OMA1 MFAP3L SPRYD7 SNUPN ST3GAL6 SHLD2 SCN1B PCMTD1 C7ORF57 GAN PBX2 LOC101676428 KCNK1 AGPAT1 WDR5B RAB3D NTPCR KIAA0513 PDK3 EFCAB14 436 genes up-regulated by SARS-CoV-2 in ferret trachea from GSE147507 SARS-CoV-2 infection of ferret trachea Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/MjuvvW9xB CEP350 ATP13A3 ERO1B PKP2 HNF4G SLU7 CENPF TDRD1 WRN RYBP ZYG11B TAPT1 SULT1B1 TMPRSS11A B2M TMPRSS11D HHLA2 PPIG POGLUT3 MAP3K1 GOLGB1 CXCL9 NAP1L1 AGBL3 C1D RDH14 INTU SCP2 NUDT12 TFAM YME1L1 PMS1 ZKSCAN1 MYO6 NXT2 TRIM37 GPR155 NBEA MECOM CP ITGA2 DDAH1 BMPR1B UPK1B PATJ KIF21A LURAP1L FOXP2 TRIM2 SCEL GALNT3 FAM83B DSG2 QSER1 FNIP2 FNBP1L SYTL5 POF1B EXPH5 SIX4 EYA4 GCNT4 CHST9 MYO5C FMO2 MAL2 STMN1 TOP2A CLSPN LPL ERI2 NEK2 SHCBP1 IFI44 ALCAM ASPM DLGAP5 POLQ KIF4A EPSTI1 KIF15 CDCA2 KIF11 CEP55 SKA1 TTK NCAPG YES1 MLF1 ST8SIA6 SLC30A4 TRAM1 ABCC5 WDR72 B4GALT6 TGFBR1 ABCE1 DSG3 KITLG SLC5A8 IPO7 DCK CBFB SMC2 UBE2T ESCO2 GATM TLR1 HELLS GZMA ECT2 ERCC6L CKAP2 DEPDC1 MAD2L1 CENPH NDC80 CENPE NEIL3 CTSS GEN1 KYNU CMPK2 HEPACAM2 IFIH1 CCDC18 SAMD9L TLR3 SLC4A5 DGKB CAV2 TXNIP UBL3 SEMA3C EIF3E NR1D2 HIPK3 ARRDC3 MBNL1 SP3 CHORDC1 CETN3 AGO4 FAM102B ARRDC4 OIT3 SCML2 RGS22 C21ORF91 TLR6 COL21A1 AQP4 FLRT3 FEM1B ZNF367 MBD4 ANP32E UBE4A MSH2 COMMD8 EIF2A SYPL1 RFC4 FAM107B HMGN3 KPNA3 IPO5 STAG2 RB1CC1 SLC25A46 CUL4B SKA2 KLHL24 PTPRD GLMN ZMPSTE24 ROBO1 ITGAV CEP76 ADAMTS14 ANXA10 ZC3HAV1 ZSWIM2 FAM161A LRGUK SYT16 ZNF566 DDX60 N4BP2 DNA2 SEMA3E NHS TRHDE TIA1 XRN1 NIPBL CCDC186 SMC5 ATRX XPOT PRKACB FNIP1 RFX7 CCDC47 STYK1 ERAP2 FMR1 BTC RAB8B XPO1 KANSL1L P2RY10 SV2B SLC16A10 FRMPD2 ABCA12 CDC14A TWF1 EXOC1 RIOK3 MTR CLPX USP33 STX7 ZDHHC20 KPNA5 PI4K2B RAP2C DMC1 ADSS2 C5ORF15 DSC1 MTRF1 TMEM209 DNAJB14 ATP7A ETAA1 AHCTF1 CLDN1 PPAT BEST3 MIER1 SSH2 AP1S3 OCLN CPNE3 ACSM3 PIH1D3 SYDE2 ZBED5 TRPM7 SLC9A4 RAB23 FAM3C GABPA SERPINB13 CRISPLD1 SENP7 SMC4 PCM1 TMEM168 RNF32 SLC38A9 RNF168 GOLPH3L UBR1 SLC30A1 LUM UHRF1BP1L SNX13 DNAH5 ELAVL4 TBC1D15 STAM2 SCAF11 SPTLC3 SLCO4C1 PON3 SULT1C4 CDK8 MYB SGO1 MTDH FBXO45 ST8SIA4 CD2AP CASP10 TXNDC9 AHCYL2 KRT23 GINS4 METAP2 HACD3 DENND6A SLC4A7 USP24 USP31 FNDC3A SRFBP1 SKIL UHRF1BP1 MIER3 CCDC60 KLHL4 REV3L UFL1 DPY19L4 STK17B MFAP3 MANEA AEBP2 CD109 SLC9A7 ZNF277 TMEM156 HSPA13 FRS2 DDIAS SLF2 ANKRD13C ZBTB40 DMXL2 DSTYK ASXL2 BTBD3 HIPK1 TMTC3 LNX2 ARPP19 FOXN2 NMD3 TMED7 PDIK1L TBC1D32 ZNF654 REST OTUD4 CPEB4 ARAP2 RBBP9 ERGIC2 CENPQ KIF5B EIF3M DDX6 RASSF9 PPP4R2 SFMBT2 DCDC2 TNPO1 ALG6 PTPN20 LOC101679377 RNF138 VPS13C THAP5 CAGE1 JAKMIP2 CCDC162P SPAG17 C4ORF33 CUL5 MTERF1 MAN1A1 CNTLN PIGN LOC101684774 CCDC158 ATP8A1 CNIH1 SHC4 TRIM66 LOC101678990 DNAJC12 SMC6 ZNF572 CSNK1G3 LOC101688321 G2E3 PLK4 DTWD1 CCP110 DENR ANKRD29 PIP4P2 CPLANE1 LOC101681442 ANGEL2 PPM1E C18ORF54 ATP13A5 RPS6KA6 TYW3 BMT2 CCDC146 MGAT5 LRP4 BDH2 DNAJC10 FAM126A MIGA1 CXADR CENPJ OSBPL11 EFR3A ZNF445 ZMYM1 SLC4A8 ACAP2 PPIP5K2 BROX KIF1B CARNMT1 TENT2 PHAX RSBN1 NIPSNAP2 PRDM10 CEP128 CDC5L RBM46 EML6 LARP4 WDR19 ADGRL3 DNAI4 MDFIC KLHL8 LGI1 DIPK2A HYLS1 OPA1 LAYN MTREX TTC33 RAD18 434 genes down-regulated by SARS-CoV-2 in ferret trachea from GSE147507 SARS-CoV-2 infection of ferret trachea Source paper: https://www.biorxiv.org/content/10.1101/2020.03.24.004655v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/MjuvvW9xB SLC5A2 COL6A1 ANPEP GMIP CHPF SUN2 BCAR1 CKM PLA2G2D COL4A1 PMEPA1 SNX31 CLDN15 SPTBN5 COL4A2 ACE AGT MFGE8 SLC5A9 PLD3 WFS1 NOS3 TGFB1 SCARB1 LRRC8A CLDN10 TLN1 NPY ENO1 ISLR SERPING1 BPIFB1 TFF3 OLFML2B GCNT3 SCGB3A1 HSPB8 NDRG2 ADGRG1 HTRA1 SLC25A23 ITPK1 PNPLA2 ARID5A RIPOR1 PIEZO1 SLC3A2 VASP GRINA FLNA GAA EMILIN2 LRP1 LMNA PLOD1 MAP3K11 INF2 RARA ITGA5 GRN LTBR ZYX LMO2 ADAM15 STS IGFBP2 ITGA7 WFDC1 PAQR4 NIBAN2 SMTN GRB10 DUSP7 PADI2 FAM20C SEMA6B SLC43A3 GLI1 B4GALNT3 LTBP4 CRIP2 TPM2 MYH11 COL18A1 NCALD COL6A2 SOX13 SLC2A4 STAC SLC2A6 COL1A1 SERHL2 MAPT FAM20A LTF ITGB4 PLEKHH3 CAMSAP3 EPHB4 SPDEF B3GNT3 NKD1 NFIC RSPO1 SOX10 POPDC2 BCL3 ZNF865 ST6GALNAC2 ATG2A SOAT2 SLC37A2 KCNN4 MYO1F BPIFA1 MYBPHL DOC2B ACKR1 ADAMTS4 PLA2G5 CACNA1G TINAGL1 SELP FOSL1 RASL10B ANGPTL4 PLAU GAL3ST4 ITGA8 ACTC1 TTYH3 BTG2 TNS1 BMP6 CYYR1 PLVAP ID3 CDC42EP1 BGN EGFL7 GATA2 TMEM204 CLEC14A CLDN5 TAGLN PRX TMEM176B PPP1R14A LTBP3 ESAM CALR LIMS2 AQP1 IGFBP7 VWF LRG1 USHBP1 CD151 ATOH8 MYO18B NTRK3 RGMA TGFB1I1 MPZ NR4A3 LGI4 CPT1C CSF1 LHX6 WSCD1 CAMK1 EGFLAM PGLYRP1 ASB2 KCNK17 ROBO4 RTN4R VASN PDE4A SLC14A1 TMEM120B GPX3 RBPMS2 LAMB1 ADCY8 CNN1 SRPK3 ZCCHC24 ARRDC2 ORAI1 GALNT18 CSRP1 IL34 GMDS MFAP4 CSK ROR2 CHAD TCAP FES RASL11A FBLN2 TESC CRISPLD2 BPIFB4 RASD2 LAMB2 SEMA3G SH3BP4 MRGPRF ETS2 RHBDF2 PTGS1 DYSF NRGN MYL9 MPO SLC6A7 HEYL ACTA2 SMOC2 LMOD1 CHST2 CDC42EP2 PNCK SEMA7A KCNQ4 NR4A1 ZBTB47 DPEP2 SLC30A3 MCAM SDC3 IGF2 IGHM SLC17A9 ANO1 ACTG2 KIAA1614 RAMP3 GIPC3 LMAN1L DUOXA2 JPH2 C1QTNF1 LAMC3 LRFN1 TSPAN11 TMEM214 PYGM RASGRP4 HPD CASQ1 CD300LG LPO FGR NFATC1 MMP14 NFKB2 ARAF EEF1A2 VTN ROBO3 CSRP2 STBD1 THBS3 SUSD2 DMPK DLL4 OBSL1 RAP1GAP BCAT2 ENG KCTD15 NCOR2 TRABD2B MFSD12 ADCY5 SFRP5 FHL3 INPP5A PLXND1 PXDN NFATC4 ADCY4 OSBPL5 PDGFRB FLNC SGSM3 NES ARHGEF15 DOCK6 TXNDC11 DCHS1 ELN GNB3 MMP7 NPR1 NKX6-1 NFAM1 AZGP1 SEMA6A VWA1 HID1 WNK2 PDGFB FOXP4 PTP4A3 PITPNM2 GPC1 MEOX1 PRR5L NDUFA4L2 APOA1 CD79A SCARA3 ABCB9 SEMA4A HRH2 FAM167B PEAR1 GJB1 AEBP1 COL5A1 CREB3L1 GPSM1 CYGB PPP1R1B HSPB7 SH2D3C PECAM1 GPX6 PLOD3 COL16A1 BCAM DHCR7 PKDCC AGFG2 ANXA6 AFAP1 TRIM47 ZBTB7C FADS3 RASGRP2 CHST11 MELTF CDK18 A4GALT OLFM2 HSPG2 SEPTIN9 RASAL1 SYT11 MPRIP PDE1C EMILIN1 ACAN PDLIM7 DAG1 SLC25A48 SLC12A4 CCNJL MMP28 SGCA GALNT15 HOXD9 RIPPLY1 P3H3 ARHGEF17 FMOD CDR2L SOX8 SEMA6C HOXD4 RBPJL ACACB MATN4 MATN1 REM1 UBALD1 SH2B2 GFRA3 COL8A2 FAM110D LMX1B P3H1 SLIT3 LOXL1 SLC26A10 BARX2 NGFR DMWD TNS2 SHISA4 TRH MAMSTR HMCN2 NECAB3 LOC101673770 RASIP1 OSR1 ANKS1A CAMK1G GARNL3 AVPR2 VWA5B2 MRVI1 TMEM132E FRMD4A CHRDL2 RASL12 SYNE3 KCNMB1 COL15A1 FBXL7 CASTOR1 COL23A1 TTYH2 ITIH5 TSPAN9 COL5A3 SPEG BPIFB2 SHF PRDM6 SLC4A3 ADAMTS7 SCUBE1 PGM5 ADARB1 PPM1F TIE1 DES TMEM63C 500 genes up-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/AvpnF4za8 IMPDH2 TIMM8B MISP PSMD8 HSPA5 HYOU1 PRIM2 VCP CISD3 EPB41L2 BCAR1 KPNB1 LMAN2 HSD11B2 IFITM3 PPT1 YIF1A TMBIM1 CDX2 ACSL3 HSP90AA1 AGPS FAM98A TUBA4A NUTF2 VARS RETSAT TRIM28 HERPUD1 OASL RCC1 NPM1 TLN2 PRKAR2A THOP1 PLP2 PLEC NAP1L1 NOL7 TRAP1 SLC33A1 CPT1A C20ORF27 DDAH2 SPRR3 SDC1 KRT18 NT5DC2 KRT7 NEBL TM4SF1 REPS2 KRT17 HES1 MT-ND6 S100P SERPINB5 S100A14 C6ORF132 RPS3A PITX1 SERPINB2 ADH1C SPRR1A KRT19 POF1B TRIM29 RPL39 NDRG2 PRSS23 S100A2 RPS18 TACSTD2 AGR2 KRT8 STARD10 RPS7 TMEM246 TAGLN2 CD2BP2 SMARCD2 BAX BANF1 TMC6 TOMM40 DDOST TOR3A FLNA DNAJB2 SUMF2 MYADM LMNA APH1A TKT PDIA4 CLUH TMED9 ARHGDIA TOLLIP DDB1 LTBR SYNGR2 PYCR1 DHCR24 TWF2 MRPL12 CEBPA AREG CREG1 POMP IGFBP2 H1FX CTSZ MYDGF EPHB2 LGALS3 RPL26L1 BATF2 PSMB2 ESRP2 CXCL8 ZFPM1 LLGL2 B4GALT1 BMP7 SLC2A6 MARS RPS2 MMP1 MANF STAT5A CDH1 PKP3 ACTB TRAPPC9 SRSF1 CLDN4 FGFBP1 PSMD6 CAPN1 JUP PLCD3 TRIM16 ADGRF4 GIPC1 SLC52A2 DKK1 WNT10A CTNNBIP1 CDK2AP2 FPGS PREB PSMA3 PTPRU MED25 DYRK1B RGP1 DDR1 AKT1S1 ARMC7 PYCARD CXCL3 IL1R2 NPRL3 HMGCS2 TNFRSF12A FOSL1 WARS SP110 ETS1 GNAI2 PTGES3 CYR61 SELK SHISA5 RPL8 DGKZ YBX1 IER3 HNRNPM PSMB10 HMGCS1 CAPZB TXN NFKBIA ID3 GSTP1 JUNB C9ORF69 SLC34A2 FABP5 RPL5 RPS19 DMKN RPL10A PPIB PSMB6 PSMC2 EIF5A PPP1CA MRPL20 C1QBP PSMD3 SH3BGRL3 CETN2 VIM RPL35 RPS9 PRPF19 ESAM PSMB4 CRELD2 CALR TRMT112 FXYD5 PSMA6 EHD1 DSTN STK38 EEF1G FASN NUDT16L1 SSR3 S100A10 CD9 TRAF1 OLFM4 KLHL11 FUS BBC3 BRD1 UBE2S MRPL24 BABAM1 LAMTOR2 PRKAG1 GYS1 S100A11 RBM42 SEC61A1 HSP90B1 SRM POLD2 CPLX1 PSMD13 LSM2 PSME3 COPRS DPP3 AHCY CCDC124 ICT1 NHP2 EBNA1BP2 BOLA3 MRPS23 TRAPPC3 PSMD14 POP5 NOL11 CCT7 SEC11C NAA10 HSPE1 SNRPE C1ORF122 LDHB SDF2L1 ODC1 NUDC HSPD1 FXR2 DUSP10 SF3A3 APOBEC3C ID1 ZNF618 GAS2L1 SQLE DOK4 CSRP1 CD47 FAM134C C6ORF47 APBA3 TRA2B GDAP1 STYXL1 CCDC94 CSK ATF6B ISOC2 ALDH3A1 BTBD2 CTSV AGR3 RPL22L1 LAMC2 EMP1 HOXA6 HNRNPL ARPC1B HCP5 ACTN1 CLIC1 BLVRB HMGN2 SERP1 HNRNPA1 SNRPB2 HSPA1L GRAMD1B PHLDA2 SEMA7A FADS2 LAMA3 ANO1 OTUB1 IRAK1 POP4 PSMD11 RAB35 FTSJ1 ARF5 PRMT1 SMG6 CA12 STARD7 ESD ERP29 GNPNAT1 TMEM11 FKBP11 FKBP2 BAK1 CD82 PSMC5 HMBS PHGDH ALG3 FCF1 STX18 PSMC3 TNFAIP1 FADD AUP1 AURKAIP1 APRT MID1IP1 ARMC6 C19ORF24 USP36 ZFHX2 PLEK2 DNAJB11 PDIA3 GTPBP10 THOC7 SPNS1 PRKAR1B ASNA1 P4HTM LSS RNPEPL1 FASTK MFSD12 RRP1 SLC38A5 TSPYL2 PELO OSBPL5 PLEKHM2 SGSM3 VPS37B PSMD2 NAP1L4 PCDH1 RPS6KA4 DHX9 ACOT9 CD320 KDM4A C9ORF152 AKT2 GPC1 VAC14 MRPL40 RPS6KB2 FOXA3 FUBP1 LIMK1 CREB3L1 PPIF PDAP1 TACC1 ZNF639 RPP30 MRPL4 RPUSD1 RRS1 IFRD2 RPS4X FBXW2 H3F3B TMED3 UGDH NAPRT OAZ2 SDHC PEG10 CBLL1 ZNF16 KDM2A FSTL3 MAPKAPK3 EBP ZNF580 ZNF579 FRMD5 HYAL2 RAVER1 ZNF703 ZDHHC12 HSPBP1 MKL2 NECTIN3 RAD54L2 GPATCH4 CCDC167 ECH1 DESI1 HGH1 RBM10 SNRPF SNRPD1 MORC2 FANCE PID1 PRRC2A SBF1 AP2B1 UBALD1 LINC00506 TUSC1 KIAA0586 RNF126 TSIX DIMT1 ENSA C21ORF59 CENPB DDX49 DNAAF5 MESDC1 RBP1 ZC3H3 FSIP2 RN7SK CACFD1 RPS14P3 ELOF1 FAM219A PIGM MGAT3 FBXW8 ESRG TAF6 LSM6 SSBP3 LOC102724532 RNA45S5 NUS1 GTF2A2 IL17RE PPP2R1B PLA2G16 LRRC75A-AS1 ZNF408 SMARCC1 TSPAN17 SNRNP35 SFXN4 LOC101930085 ATAD3B NABP2 BLOC1S3 RMND1 FAM118B ATP9B ZAK TMEM63A VAPB PYCRL PDE6D KRTCAP3 ZNHIT6 AES ADPRHL2 LOC101927391 MED27 500 genes down-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/AvpnF4za8 MAOA MOGAT2 TM4SF20 SLC10A2 ERICH4 CES2 SEC16B NAALADL1 FCGRT CPO DPP4 PBLD TM6SF2 SLC17A4 ANPEP CYP3A4 MDN1 TMPRSS2 PRAP1 BTNL3 SI DGAT1 C1ORF115 AADAC CDH17 HIST1H1C HNF4G PCK2 ALPI CREB3L3 GUCA2A UGT2A3 MME ACADM RBP2 MACF1 NPC2 MYO1A ACE2 MYO15B SMIM24 GPT MTTP SEPP1 GBA3 XPNPEP2 ACSL5 FABP2 SLC5A1 SLC6A19 NDRG1 CRYL1 VILL CENPF GPA33 SLC46A3 MEP1B LRRC19 USP2 SLC28A1 SLC15A1 ENPEP SLC7A9 CLRN3 PLS1 SULT1B1 PHGR1 PKLR AOC1 TRIM40 PLOD2 FABP6 ACE GIPC2 TM4SF5 TMEM176A ABCG2 BRCA1 SLC5A9 CLCA1 MUC3A TDP2 PCK1 GLOD5 MUC17 MGAM PEPD DHRS11 ITM2A ADGRG7 TRIM31 MEP1A HHLA2 AKAP9 ALDOB STOM C17ORF78 EPHX2 GUCY2C FLJ22763 C11ORF86 TKFC MS4A10 MUC13 FCGBP CDHR2 TMEM236 UGT2B17 TMEM253 TMED4 SAT2 VPS13B AQP11 ELL3 UCA1 LINC01133 AK4 PIGR AUTS2 SLC40A1 MT-ND5 SYTL2 DUOX2 METTL7B SMPDL3A MT-ND4L SCIN CYBRD1 MALAT1 ATOX1 TFF1 GSTA1 PSCA LCN2 ANK3 MT-CO2 DHRS9 TMBIM6 AQP3 STMN1 GPD1 GRN FLVCR2 TOP2A CCNB2 SLC35A5 UBE2C AURKB HADHA GLRX NEK2 HMMR BUB1B SLC39A11 ASPM RNASE1 ESPL1 RRM2 SHMT1 PRR11 HEBP1 TPX2 CCNB1 FER1L4 CBR1 CDCA3 MKI67 LDHA LIPA TBC1D2 GNPDA1 MGAT4A ADIRF AUH SLC2A5 ABCC2 B4GALT6 ABCG1 RHOU MAF CCDC170 SYNPR CENPK CENPN PTPN22 QPRT CFB ESCO2 IL18BP GATM RETNLB CCL20 NUSAP1 KIF20B HMGB2 CENPE KIAA0101 APOBEC1 CIDEC CA13 GDPD2 LYPD8 SLC3A1 FTH1 ACER2 SGK1 HPGD IRF9 ITM2B CLIC5 GDPD3 CA2 NPNT VEGFA CST3 PLIN2 TMEM176B IMPAD1 BNIP3 PDCD4 PTGR1 FUCA1 CA4 IL2RG ALOX5AP GNS CD36 OAT ACADSB GLOD4 BNIP3L ARRDC4 ZC3H12A NOS2 MLN OTOP3 KIAA1551 GSTA2 AQP7P1 ZNF292 TTR BCORL1 MS4A8 GPX3 PFKFB3 PDZK1IP1 SUCLA2 PI3 SPCS1 ELOVL7 AP3S1 SEC23A MXI1 SUCLG2 BTD FAM13A NEAT1 TNFSF15 RNF19A HACL1 KLHL24 FUOM HLA-G SPPL2A PIGZ CHAD GCHFR TFF2 TNFAIP8L1 SLC6A4 CPNE2 SLC43A2 LOC100287497 VNN1 PTGR2 SLC51A C6 MCM7 ABAT SMG1 CEACAM7 SLC26A2 STARD4 C19ORF66 TRANK1 EFHC1 ATRX ZNF223 RFWD3 ONECUT2 CEACAM1 GPT2 GLUD1 ACHE MDK BLNK SERPINA1 CDA COX6C KLK7 LOC154761 PAG1 PNCK A1CF PTPRR RARRES1 CA1 ORMDL3 RIOK3 GK NAAA CYP2C9 IFNGR2 XPNPEP1 STX12 SLC35F5 HAPLN4 AIG1 CALCOCO1 C4ORF3 ZC3H11A SUV39H1 HELZ ECHDC2 PTER ALDOC SUSD2 ING2 GOLGA4 TMCC1 CPS1 ADI1 MATN2 PRODH ZFYVE26 SFRP5 SLC37A4 YPEL3 TPP1 NFKBID GGA2 DST SREK1 KDM5D RNF123 GLS SLC5A3 AKR1C4 APOC3 APOB SLC26A3 SLC51B SOWAHA MUC2 GDA G6PC ZG16 NAT2 LCORL FAM3C KDM3A SMLR1 CDK19 FXYD3 PROM1 CYP3A5 CCNG2 CYP27A1 ERBIN EEF2K CYP2C19 APOA1 SLC39A4 HK2 SESN3 PLD1 ZNF224 NUMB WDR48 GIT2 TBC1D15 RANBP9 CYP2U1 SULT2A1 FMO5 PLA2G12B FLVCR1 GSTM4 BAAT LEAP2 GLTPD2 UGCG DMTF1 AFP CD2AP SLC11A2 MT1G ETFDH HIBADH HECA MAGED2 SLC4A7 ASAH2B SLC25A37 MAOB LGALSL MANBA ESPN CPD PGRMC2 PYROXD1 GALC PHLPP2 NME4 ANKRD10 DNAJC25 PDE8A CREB3L2 PHYH VPS13A DIRAS2 LINC01559 PPP2R3A APPL2 PALM3 TMEM41B NCMAP LDHD ETNK1 DGKA SIN3A ZNF770 INO80D ADCY9 RAB3B MSL1 BTN2A1 PDK3 BDH2 CENPJ SLC35G1 UVSSA LINC01602 TMEM120A MT-TV RALGPS1 ATP11B ZHX1 NAT8B TMEM220 PDXP LAMA1 MLH3 TMEM92 MTURN TUBG2 ALDH18A1 C2ORF88 SLC6A8 KCTD13 COPS7B FARP2 MT-TT DAB2 LOC105377924 TBCK IYD RNF186 DNAH12 COG8 LOC389602 CLYBL LRRC28 C11ORF72 LINC01224 TBC1D23 HOXB5 GOLGA2P5 CDKN2B-AS1 FADS6 C9ORF40 TPK1 ANKIB1 BMS1P5 SESTD1 LOC101928820 CNNM1 WDR60 C3ORF62 ERP27 GABPB2 NDNF U2AF1L4 LOC100506098 LOC105375166 GAB1 YBX2 SSUH2 ARHGAP26 PRDM7 500 genes up-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/stZItPsep SLC36A1 SRP19 F2RL1 TIMM8B RAB2A EGR1 CTSL GHITM COMT NMI PKP2 TOM1L2 GUCA2A HSD11B2 TPM4 RALA NGDN ANXA2 FABP2 BAG3 LRRC66 RAB18 OAS1 AGPS PHGR1 TUBA1C ANXA13 CYP2C18 CUL2 ABCG2 TSPAN8 KRT20 CXCL2 HSPA8 FRMD3 RAB10 KALRN ARL14 MYD88 LRRC1 TPMT ABHD3 CD55 RWDD3 ALDH1A3 MCL1 CAV1 CDK2AP1 LINC01133 KRT7 KCTD1 CFTR RGS2 TM4SF1 IFI27 HS3ST1 KRT17 IL33 CCDC84 NR4A2 GCNT3 S100P SERPINB5 HOPX MT1E MTRNR2L1 BCAS1 GADD45A RND3 TACSTD2 AGR2 COPS9 MAL2 CD24 THBS1 HBEGF RPS6KA1 SF3B4 UNC13D TYK2 TMED9 RHOB TUBG1 ME1 NLN AREG POMP SEC23B RGS16 HSD17B10 IL18 LGALS3 NME1 CDKN2B IFI27L2 ARNTL2 CXCL8 AKR1C3 ARHGEF35 CAMK2N1 MMP1 GADD45B EDN1 CYCS GJB3 CGN FGFBP1 PSMD6 FAM84B PLCD3 TRIM16 EREG KITLG CLU DKK1 CBX4 PDLIM5 PYCARD PSAT1 CXCL3 IL1R2 IL1RN PLAC8 IFIH1 MLKL SOCS3 ARC GCH1 HPSE AIM1 F3 AHR CAV2 EPAS1 TNNC1 HNRNPM ACTG1 SGK1 CRYAB MYL12B DUSP1 TMCC3 ID3 KLHL5 HPGD JUNB CLIC5 SMAGP JUN CA2 CTGF FABP5 COX7A2 ALDH1A1 PSMB6 PSMC2 MRPL20 RAP1B NDUFB3 DHX15 FDX1 HSPH1 ROMO1 DNAJA1 RBM3 FSTL1 STK38 ANXA1 SERPINB6 LXN NDUFA4 POLR2K GTF2B ATP2B1 ACYP2 MRPS18C S100A10 CACYBP GEM HSPA6 PPP1R15A SULT1E1 AMOTL2 FLRT3 IER5 BAMBI CHAC1 SLC25A33 NR2C2AP UBE2A SNRPG HAT1 SELT NQO1 MCRS1 ASNSD1 PSMD1 ATP6V1C1 TXNDC17 S100A11 CRYZ C12ORF29 ATP6V1D UBE2N TEX30 DYNLT1 AHCY TMEM126A MCUR1 EBNA1BP2 TMEM14A TMEM230 BOLA3 GSKIP UGT8 TRAPPC3 COMMD8 ATG5 FAM96A AMD1 STEAP1 PRPF3 ETHE1 PSMD14 LACTB2 ELOVL7 SEC11C GLRX2 HSPA1A YAE1D1 C1ORF122 HSPA2 C3ORF38 MRPL18 ARG2 SLC25A46 ODC1 GRHL3 DNAJB9 SGMS2 PIP5K1B SRSF2 ID1 SAMD4A SURF2 AKR1B10 SRI ID2 ZMPSTE24 MCC CD47 CEP76 MRPL47 TRIAP1 TCEB1 TRA2B ANXA10 ASCC3 RIPK2 RNF139 KATNA1 INPP1 HNRNPF IFI6 TMEM126B KIAA1279 MBNL3 CHAC2 C10ORF99 MIR22HG CASP7 CORO2A PJA1 PKIB XRCC4 EMP1 MB21D2 TWISTNB TGS1 SNHG9 PLK2 ZNF649 PMAIP1 SP140L NMUR2 NCEH1 FAS FUT4 BLZF1 C8ORF4 RAP2B CALM2 UGT2B15 PRKAG2 PDLIM2 TRIB1 PHLDA2 SERPINB8 SLC25A32 TUBB3 ANO1 PLSCR1 NCOA7 C4BPB RARRES1 SFTA2 CA1 PSMC4 FBXL5 TIMM23 PSMD9 VPS29 RTCA GTF2H5 SACM1L C3ORF14 NAGK STX11 GK TAF9 ZMYM4 DHX35 PPP4R1 AKIRIN1 C12ORF45 TPM1 BHLHE41 ABHD16A ANXA4 ABHD5 KRT10 DEGS1 MID1IP1 MTA2 DCAF13 EPHA2 BCCIP CLDN1 NT5C2 RPF1 DNTTIP2 PTP4A1 MRPL33 CLTB MPC1 NBN CCDC71L ATP6V0A2 PLXNA2 PPP2CB SFT2D2 SLC26A3 OSTM1 KDM6A FERMT1 FUNDC1 POLR2F PRR5L CYP2C19 PPM1D TAF2 PIGG GCLM AKR1C2 CIAPIN1 NAT1 BAAT AKR1C1 ACOT4 NIPAL1 LMO4 TRAF4 SFPQ GPAT3 PRMT6 PSMA5 FAM136A ZCCHC10 RPP30 HUS1 CCNC TXNDC9 MT1G CLN5 MGST3 TIMM17A AHCYL2 CLDN23 KRT23 ANXA9 ADGRF1 POLR2L MFSD1 ADGRG6 USP42 ABTB2 SKIL MIR31HG MRPL41 DSEL SLC22A18AS MRPS21 MFSD2A LOXL4 DSC3 DCUN1D1 SDCBP2-AS1 LY6D PCDH7 YTHDC2 CRNKL1 ZNF697 TRIM36 GPD1L HSPBP1 LGR4 DNAJC9 FRS2 ADNP2 ANKRD13C BICC1 TRAPPC8 PHACTR2 PDE12 RAB27B FOXN2 SLC20A2 DTWD2 PALLD TMCO1 PHKA1 COA6 HIGD1A MGST2 PID1 ATP5F1 LYSMD3 DCDC2 AGA LSM10 DUSP14 BTBD10 OPA1 MMP28 FSIP2 RN7SK NUS1 GTF2A2 ATP9B LOC101927391 LOC105377924 NCDN KIAA0196 ZXDC TSPAN2 FAM177A1 ALG2 CCL15 WTH3DI UFD1L ARHGAP42 ITGB1BP1 TRUB1 SPAG1 ZMYM6NB MT-TM STRAP FASTKD1 ENTPD7 SLC25A24 CRYZL1 DFNA5 HNRNPLL DUSP11 RABGGTB MINOS1 DPCR1 MOB3B MED8 WFDC21P RBM45 SHTN1 TSFM MRPL19 NHSL1 NUP35 BORCS7 NCBP1 LOC105369340 DPH3 EPT1 SNAP23 OGFOD3 MARCH3 LINC00941 OVOL2 KIFAP3 TRAPPC13 ZNF271P SMG8 500 genes down-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/stZItPsep MAOA ANO9 MOGAT2 CEP250 PIK3R2 CEP350 FCGRT COL6A1 ATP6AP1 ANPEP MDN1 PRAP1 SUN2 SMOC1 UBXN6 TRIB3 VHL RRP9 SLC26A6 RNF24 SMIM24 TYSND1 TMEM97 SLC22A18 UNC93A SLC5A1 PRRC2B NDRG1 KCNQ1 CDHR5 CENPF SLC15A1 MPZL3 PLOD2 FABP6 ACADVL HLA-A TMEM176A ISYNA1 CYB5R3 WASF1 TMUB2 PLD3 MUC3A PCK1 MEP1A BRD4 HHLA2 USP21 APP CSNK2A1 TKFC REN REEP6 FCGBP PIGU STC2 DHTKD1 SBK1 ZBTB44 FGFR4 NDUFV1 ZKSCAN1 IKBKB TFF3 MCF2L AK4 PIGR ECM1 AQP5 DUOX2 DEPTOR NFAT5 GATAD2B SMPDL3A PNRC1 TNS4 KIAA1324 TET2 SLC2A1 HIST1H2BD MALAT1 LCN2 KCNQ1OT1 SLC25A23 SYBU TMEM94 MAN2B1 TMBIM6 PDIA6 LGALS3BP DAZAP1 PRKCSH GRINA GAA GIGYF1 TGFBI KHNYN QSOX1 LRP1 SLC16A3 SLC6A6 TOP2A P2RX4 DDIT4 TMEM38A LGALS1 RNASE1 H1F0 RRAS SLCO4A1 GAPDH PRR11 HDLBP TPX2 MKI67 SH3PXD2B TPI1 SCD FGFRL1 CDKN1C COLGALT2 PBXIP1 IGFBP3 TGFBR3 KLF11 AXL FGFR1 HMGA1 TMC4 COL17A1 LAMB3 SERINC2 INPP5D CASP2 MAP2K6 TRIOBP SYNPR DYRK1B RERE MGRN1 ZNF385A ULK1 SMARCA1 QPRT DENND1C CYFIP2 CKAP2L IQGAP3 RETNLB LCK CENPH KCNN4 CENPE APOBEC1 PLIN1 RNASE4 PML CLDN2 ANGPTL4 SPAG4 DBP TSC22D1 BTG2 IGFBP4 HPCAL1 TXNIP TPPP3 CLIC3 U2AF2 VEGFA BCAP31 LUC7L3 TMEM176B HNRNPUL1 CCNI BNIP3 CDK16 FUCA1 PSAP FXYD5 FAM134A RBBP4 MKNK2 SAT1 WDR45B CYP2S1 BNIP3L KDM6B ASCL2 OLFM4 ZNF292 INSR MUC1 SEZ6L2 MIR210HG BHLHE40 PFKFB3 PDZK1IP1 YPEL5 NPTN-IT1 YIPF3 WDR54 PAM SLC39A10 FAM60A KIAA0430 MXI1 RLF FAM13A SYT13 GRB7 OGT APOBEC3C NEAT1 EFNA1 ZNRF3 VEGFB KLHL24 NARF CLIP2 CDCA7 MLXIPL EFNA3 ZBTB22 STXBP1 NUDCD3 FUOM MSLN PIGT HLA-G NLGN2 TFF2 DGAT2 TNFAIP8L1 SLC27A1 PTMS TESC AARS PELI2 PRSS2 VNN1 ARID4A CEACAM7 IDH2 MLEC CCNT1 GLG1 PRRC2C TMEM107 BBX KDM5A UCP2 ASH1L IGF1R ANKRD12 CEP290 THOC2 CAPN12 ETS2 LETMD1 PMM1 N4BP1 TRIB2 BRI3BP CA9 ENO2 SERPINA1 ALDOA CTSA CDA TRAF5 NAV1 MEX3A PDK1 DOK7 SMOC2 SNHG7 EGLN3 LEMD1 CLK1 PAG1 DNM1 TMEM255B ADAM8 GAL3ST1 PTPRR GABRB2 ANKRD34A KCNH2 TNFSF9 CXCR4 TNFRSF1B IFNGR2 FAIM2 RAB5B ATG9A IFITM10 CALCOCO1 CMTM7 PARM1 MPHOSPH8 TSPAN5 ANKZF1 ZCCHC7 EIF2AK1 SMIM3 ALDOC TMEM123 SLC39A8 P4HA1 GOLGA4 TMCC1 ZMYM2 CDCP1 ATXN1 PGPEP1 PPP1R3B TRAPPC6A SYNE2 ATP9A POLR2A SLC37A4 EPHB3 REPIN1 BCL6 YPEL3 TAF1 FARP1 TBCD C6ORF106 SGSM2 GUCD1 RPS6KA2 GSDMA PRSS8 TNFRSF11A HILPDA HNF1B PPARA KLK1 SLC5A3 EXOC3 VAMP2 SREBF2 HDAC4 KDM3A ARID1A SEMA6A USP28 PLXNA3 SMARCC2 ZBTB4 CDK19 PTPRF SYT7 WNK2 CHD6 EHMT2 CYP3A5 PDGFB SETD5 P4HA2 RBPJ FOXA2 DHPS UBR4 SLC39A4 DNM2 USP49 GSTM3 HUWE1 PHKA2 POU2F1 CRAT PPP1R9B SOX4 PPP1R1B SLC11A2 ERO1A AHCYL1 TMEM219 NYNRIN CTDSPL FAM213A PFKFB4 NIPSNAP1 ZSWIM4 C6ORF223 OSBPL7 NRM HES6 PLEKHB1 ANXA6 NFIX ZNF395 ESPN DENND4C KDM5B ZC3H6 LOC100506548 ZFP90 PDK2 ZNF703 RNF43 KAT6A CDK18 ABHD14B STX10 MACROD1 GRAMD1A NME4 LHPP DHRS3 ECH1 GPATCH8 RPRD2 BAZ2B PFKP C11ORF68 BCKDHA PHF13 SNAPC3 PRKAB2 SNTB1 ZC3H13 PALM3 TCF20 ZFC3H1 HSPA12A IDUA PDK3 CCDC146 LRP4 ESRG IL17RE TMEM63A TMEM120A PDXP MLH3 TMEM92 SLC6A8 RNF186 HOXB5 CNNM1 NDNF YBX2 C6ORF136 ZMYND8 ZNF766 PDP2 ADCK3 PCCA ADRBK2 ITPR2 PDE4C CCNY PRR36 PWWP2A ADRBK1 LOC729348 ZNF652 ANKRD26 PALD1 RGL3 C8ORF58 RFX2 BRD3 MGC57346 ANKRD37 PIP4K2B FAM193A C11ORF49 SRRM1 LDLRAD3 COLCA2 BPTF NBAS LINC01011 LOC113230 ZMYM3 GSAP INAFM1 LOC100131257 ATXN7L3 AP4B1 NPSR1-AS1 NKTR ARHGEF40 MCM8 HIVEP3 GPR153 SORBS1 CADM4 FAM222B CNNM2 VOPP1 DNAL1 MARCH9 HCG8 500 genes up-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/luyfjI1qP MYH9 MAOA NKX3-1 MOGAT2 MISP CES2 CAPN5 MVP STAT3 CTSL UBD CISD3 BTNL3 SI AADAC DDX58 RBP2 LSAMP MYO1A DPEP1 ZZEF1 HSD11B2 CCND3 SLC7A7 IFITM3 IFITM1 GBA3 FABP1 DDX1 ISX KHK SLC6A19 TPRN HLA-B GPAA1 NFKB1 ACAA1 BAIAP2L2 TAPT1 POFUT1 DMBT1 COL4A2 CYP2C18 TST ACE STAT1 HGS ARHGEF11 TMEM173 LGALS4 PEPD DHRS11 OASL ALDOB MOV10 AKR7A3 ISG15 EPHX2 SRC AGPAT2 DIAPH1 GSK3B NUB1 TKFC DNAJC19 PLEC MX1 UGT2B17 RIOK2 ACBD4 METTL7A NDUFV1 SGTA DCTN2 TBCB KRT5 MT2A PIGR IFI27 KRT17 SCGB3A1 TSPAN6 MT1E METTL7B CXCL17 LINC00342 ADH1C ZNF827 KRT19 KRT15 TRIM29 SLPI ATOX1 S100A2 SORBS2 GSTA1 PLA2G7 KCNQ1OT1 STARD10 FTL TAGLN2 CD2BP2 TTC14 OGDH PYGB KCNK6 GPAT4 BANF1 AQP3 TAOK2 SIK2 DDOST C15ORF39 SLC3A2 DHRS7 STEAP3 PCNX3 FKBP8 CD81 GPD1 APOL2 RHBDD2 AK2 SDC4 CEBPA STS SPR MT1F KIAA0930 SLC39A11 TIMP4 NDUFAF3 ALG14 EPSTI1 MPDU1 GSTO1 G6PC3 VPS25 PADI2 CBR1 MKI67 SORT1 AKR1C3 TFDP2 B4GALT2 ABCC2 SERPINF1 SLC2A2 TRAPPC9 JUP KRT14 MYH14 LRP6 BCL9 BMP3 IRF8 CDK2AP2 TFCP2 SOX6 KRT13 BMP1 EDC4 CLCN5 CCDC9 DYRK1B RBM47 AKT1S1 EPN1 RSAD2 CYFIP2 PYCARD IFIT1 IFIT3 HLA-F OAS2 XAF1 BCL2L15 TREX1 TRIM10 MAB21L3 HERC6 TNFRSF12A HSH2D XDH SERPINA3 TRAFD1 UBE2L6 SP110 PSENEN PSME2 SHISA5 DGKZ AKR1A1 THRA CAPZB ID3 GSTP1 KLHL5 IRF9 MED18 C9ORF69 P4HB CRIP1 SCGB1A1 ALDH1A1 GABARAP KLF9 IFI44L NDUFS3 PRDX5 VPS28 EIF5A ATP5D TAPBP LYPLA2 CALR HN1 MRPL28 RBBP4 GUK1 PPIC OAT ARRDC4 KDM6B CLEC2B GSTA2 SULT1E1 HERC3 NPDC1 MS4A8 C1ORF233 AMOTL2 BRD1 HMHA1 ZNFX1 PRR13 M6PR ATP6V0D1 CCDC124 TMEM14A GSS UQCRQ LYSMD2 ZNF593 ETHE1 NDUFA9 EMC9 XPR1 TLDC2 APOBEC3C ID1 GOLT1A RRAGC HACL1 LINC00543 TRIM41 C15ORF48 MT1H MLXIPL FUOM GDAP1 MOCOS GSDMD ANKFY1 TMEM212 ACTN4 ALDH3A1 IFI6 LOC101927021 MT1X MAN2A1 ZNF623 TNFSF13B C10ORF99 MX2 HERC5 CHD4 PPP1R3D PAQR8 PAPSS2 LINC01087 GHET1 OSR2 LINC00896 JADE2 FAS PXK TRIM26 BRI3BP SERF2 CALM2 CXCL14 KRT6A ANO1 ASPDH FCHSD1 LOC100419583 CHN2 CA1 PLAGL2 SEC13 USB1 SSU72 BCL2L14 CASP9 DPP9 TXN2 YIPF1 TOM1 HMBS TMEM199 ALG3 COQ4 SUCLG1 ZNF471 TIGD1 SCD5 CHMP1A C9ORF16 BST1 APRT COMMD3 C11ORF80 SLC25A10 IP6K2 STAU2 DNAJB11 SUSD2 CPS1 FAM173A PGPEP1 CLTB MATN2 VPS18 NCOR2 NOX1 SFRP5 SLC37A4 KATNB1 PPDPF ATP6V0A1 ILVBL ACP2 TSPYL2 URB1 POLR3A APEX2 SLC52A3 PRSS8 GLS SLC26A3 SLC51B CMBL RAB40C ZBTB21 AKT2 AMBRA1 CYP27A1 CPTP ABTB1 NR1H3 GPLD1 HAAO BAAT LEAP2 ACOT4 HOXA1 VPS4A BRMS1 ORC5 MRPL4 GRWD1 TXNRD2 MAP2K2 MT1G ECHS1 FMO4 SDSL JOSD2 PDSS2 SLC4A7 LINC01420 KANSL3 FOXJ2 CBLL1 MID1 ZSWIM4 SLC25A37 C7ORF50 KCNMB4 MRPL41 ANKRD54 PXMP4 ESPN KLHL13 FAM198B SNX24 ZDHHC12 NOC4L HGSNAT ZMIZ1 LINC00511 FAM217B ABHD14B CIB2 POLR3D SMYD5 SNRPD1 ERGIC3 MFSD4B SMYD2 SSPN PLPP5 CACNG4 ACOX2 GGACT PRLR AMT RLIM ST6GALNAC4 ZNF445 KLHL8 OPA1 LINC00506 TSIX MGAT3 FBXW8 ESRG TAF6 RNA45S5 LRRC75A-AS1 TSPAN17 NABP2 CRYZL1 DPH3 LOC729348 ZNF652 NBAS LOC100131257 ABCC13 SCAMP5 BLOC1S1-RDH5 ROR1-AS1 ACOT11 PRR26 ZIM2-AS1 DSN1 SUSD1 DPH7 GUF1 C17ORF89 LINC00504 LOC153684 DENND2D UGDH-AS1 FOXE1 PODXL2 MCF2L-AS1 CCDC18-AS1 SCAPER LOC101929486 C3ORF17 ASCC2 LINC00368 MIR205HG ZNF738 AAMDC RAB3IP C16ORF95 OCEL1 NHLRC2 LOC105372751 MAP2K5 LOC101928103 MT-TL2 MMP24-AS1 HHLA3 IFT140 ZNF622 RHBDD1 FAM234A LOC729987 MTRF1L CCDC144B MFSD10 SMIM19 LINC00670 C18ORF8 DCTN4 LOC101928068 TAF9B PROSER1 LOC102724434 ZNF584 PABPC1L ABHD17A EXOSC6 FTSJ3 C18ORF61 SGK223 500 genes down-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/luyfjI1qP TM4SF20 SLC10A2 HDAC2 GDF15 MDN1 SPOP NPTN TRIB3 RBL2 EP300 PKM ZC3H18 NEDD9 CENPF HSPB1 XIAP EHBP1 NCK1 REG4 ATP1B1 PLOD2 FABP6 BRCA1 SLC30A7 PCNT MUC17 ITM2A UNC5CL TRIM31 USP21 STOM CCDC86 ARL14 CDK2 LRRC8A USP34 LYRM2 TMEM30A FGFR4 CD55 UNC119B NAE1 H2AFY2 UCA1 CEACAM6 TFF3 MT-ND3 CXCL1 CLCA4 MCF2L ITGA2 AK4 FAM114A1 NT5DC2 SRGAP1 AUTS2 CEBPD RPL14 MT-ND1 MT-ND5 GCNT3 DUOX2 KLK11 TEAD1 TNS4 DSG2 BCAS1 RPL13A C12ORF75 MT-CO3 SATB1 TFF1 MT-CYB CEACAM5 MT-ATP6 MT-ND4 MYO5C EMP2 DHRS9 CD24 MPZL2 STMN1 GSN TGOLN2 SIN3B ABHD2 PLK1 C1ORF43 XXYLT1 UBE2C SLC16A1 DDIT4 LHFPL2 MCM2 UACA ASPM RNASE1 CDK1 SPRY2 GAPDH TPX2 CCNB1 FER1L4 LDHA SCD ANG TOPORS FAM131B TCN1 TGFBR3 AZIN1 AUH KLF10 BMP4 TLDC1 MLPH COL17A1 SYT8 SEMA4B PPP1R13L MST1R MCCC2 SLC7A1 WLS TCF3 SYNPR AP5B1 KMT2B ARHGAP35 TAB3 PLEKHG3 SMARCA1 SMC2 RETNLB ECT2 KIF20B MAD2L1 COTL1 CENPE KIAA0101 CIDEC PSAT1 PRSS22 TMEM143 RNASE4 TINAGL1 F3 TSC22D1 ACER2 RNF7 VEGFA S100A4 LYZ SERPINE2 SLC12A2 IMPAD1 RPL18 DDX3X PIM3 NAB1 PHLDA1 PRPSAP1 WDR45B CCNL2 MARCKSL1 UPF3A CD164 SLC38A2 BNIP3L DEK ZNF292 UNC5B GPX3 CALB2 TIPARP BHLHE40 TAF1D MAFF SNHG1 PFKFB3 PPRC1 TM4SF4 UBE2M RRM1 CRYZ SLC29A1 UBE2N PCNA TIMP2 PTMA DKC1 PAM MRPL16 PTDSS1 BZW1 TMPO FAM60A MPLKIP PPP1CC HSPA1A AMIGO2 MXI1 SNHG8 SERINC5 FAM13A RHPN2 SYT13 GRB7 DLAT MRPS6 DQX1 EFNA1 EPB41L4A-AS1 TNFSF15 INSIG1 NCBP2-AS2 CEMIP ITGAV NECAP1 EFNA3 HLA-G ANXA10 MARS2 USP25 PIGZ ADPRHL1 TFF2 TNFAIP8L1 PCSK9 CTSV MMACHC ABAT CCDC68 BBS2 CEACAM7 MIS18A SPIN4 BCL10 GORAB ST3GAL1 TOP1 ATRX FEM1C TP53BP2 XRCC4 ZNF223 HPS5 PATL1 NMUR2 RABGAP1L TRIB2 PARP3 RAB8B NMU CA9 CDA KLK7 GNE HPDL EGLN3 LANCL2 XYLT1 FHL2 PNCK TNFRSF10D KLK6 PTPRR FFAR4 ITGA6 NUBP1 GLRX3 PSMD9 AASDHPPT UBA2 IDI1 GK CREB1 CYP2C9 EGLN1 SC5D SEPHS1 NUP153 TMEM43 APIP HPF1 GEMIN8 VSIG1 CHMP1B C4ORF3 CAPRIN1 ABHD12 DEGS1 LPCAT4 ZC3H11A NDE1 STRA13 TBX19 EPHA2 ECHDC2 KTN1 USP53 DNTTIP2 ALDOC TMEM123 P4HA1 BRIX1 SMIM13 TMCC1 PMF1 BOLA1 COL27A1 FA2H MYEOV TET3 MZF1 KLK10 VPS13D NISCH TRIP10 AGFG1 HILPDA SLC5A3 APOC3 NPEPPS INSIG2 FXN KDM3A PTPN11 SLC44A4 FXYD3 PROM1 SRPK1 FERMT1 PCM1 R3HCC1L CLMN MIA3 DAPK1 UBR5 ATP13A2 UBIAD1 SLC39A4 HK2 TRPV3 DNM2 ZNF19 ZNF641 SPICE1 NUMB MTHFD1 GSTM3 ABCA2 SAMD8 AP1AR CLINT1 TGIF1 HOXB4 FAM136A FBXO45 CDCA4 C11ORF84 AFP GATA6 ING1 SLC11A2 ERO1A OXR1 ASPH NYNRIN ADGRF1 DENND6A TNIK ASAH2B GGA3 KIAA0753 ELMSAN1 C6ORF223 GSE1 HIVEP1 RBM14 JMJD8 GJB4 ANKRD50 CPD TMEM131 STON2 CABLES2 MYRF ARFGEF2 RBMXL1 CDR2 TAF5L CLIP1 NME4 ARHGAP12 ANKRD10 GPATCH8 MAK16 KYAT3 HSDL2 SOS1 DIRAS2 PRRG4 RASAL1 LINC01559 KMT2D ATP11A TBPL1 MZT1 SPA17 TMEM41B GRHL1 CEP95 USP37 B3GALNT2 ZNF770 HOXA3 RAB3B MSL1 MLLT6 RAB3D THAP5 ACAP2 LOC101927391 LAMA1 SLC6A8 LOC105377924 IYD RNF186 HOXB5 CNNM1 C3ORF62 NDNF U2AF1L4 SSUH2 DUSP11 TSFM MARCH3 ZMYND8 ANKRD26 GPR153 HCG8 PARN BCL7B SLC17A5 SLC35B2 INIP C17ORF100 PKNOX1 ZDHHC8 SENP5 ADGRL1 KRT42P ESYT2 MRPL10 CHAMP1 OR2A4 DDX47 THAP10 PDS5A GTF2A1 SETD9 RUFY1 OLMALINC LOC101929128 HINFP SAV1 STX1A MRPL39 APBB3 CHST14 SEPT6 FAM109B TMEM69 ARHGAP39 CHM FAXDC2 TCFL5 CACNB3 LINC01057 SERAC1 ENOPH1 ZNF337-AS1 ZNF717 OBFC1 UMAD1 SNX30 C2ORF42 ELF2 LOC644794 BRWD3 MRM2 FAM213B COIL SEC22A TMEM170A PDS5B LYAR MYOM3 CROCCP2 500 genes up-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/F72PQSTJV SLC36A1 NKX3-1 FOXRED2 DCTPP1 SLC10A2 TIMM8B XPO6 ANPEP NMI HRAS KPNA2 AADAC DDX58 EXOSC8 GUCA2A RBP2 CXCL10 ACE2 IFITM3 CXCL16 PPT1 CYP2J2 IFITM1 MTTP FABP2 LAP3 SLC46A3 USP13 MEP1B HSP90AA1 ALG5 SLC7A9 OAS1 PHGR1 SLC27A4 DNMT1 TUBA1C REG4 ANXA13 CYP2C18 STAT1 EIF2AK2 ALG8 RAE1 PEPD TIMM10 OASL ALDOB CXCL2 ISG15 HSPA8 MX1 RABEPK EI24 CISD1 EXOSC4 SAC3D1 ATF5 DANCR MT2A KRT18 STOX1 RGS2 IFI27 MT-ND1 SERPINB5 HOPX MT1E MT-ND2 ATOX1 GPRC5A TACSTD2 AGR2 KRT8 MYO5C COPS9 CD24 SRRT CD2BP2 SLC3A2 PGD HBEGF SF3B4 PPP1R12C CD101 CCT5 EXO1 ZWINT CLSPN TK1 EZH2 PLBD1 IFI44 MT1F MTCH2 ANXA5 RRM2 PAQR4 CDC6 EPSTI1 IL18 NME1 CDC45 DTL PKD2 CYP4V2 ABCE1 EDN1 FOXM1 SRSF1 CNKSR1 CEP170B SPDEF WDR7 CLU DKK1 NUCB2 DHX34 RSAD2 OAS3 FIGNL1 EME1 TCF19 RAD51 CHAF1B FAM83D OIP5 IFIT1 AUNIP MELK ZWILCH NDC80 KIAA0101 PSAT1 IFIT3 OAS2 POLE2 XAF1 CXCL3 GINS1 IL1R2 IL1RN CMPK2 IFIT2 C5ORF28 HERC6 IFIH1 MLKL ADAR PARP9 PARP12 ARC SAMD9L HSH2D IFI35 PARP14 UBE2L6 WARS SP110 ACKR4 C1ORF56 PSME2 LY6E HNRNPM TUBA1B SGK1 ARL2BP IRF9 CLIC5 CA2 SLC34A2 CTGF FABP5 H2AFZ MAT2A ALDH1A1 IFI44L EIF5A MRPL20 QDPR JTB LAMTOR1 CRELD2 LXN CD36 ANAPC5 SSR3 ZNF880 NOS2 TRIM22 KBTBD8 SLC2A11 CHAC1 ZNFX1 ERI3 SNRPG HAT1 HMGB3 POLR2G CDC123 PSMD1 SEC61A1 MRPS33 DCXR TEX30 PSME3 TIPIN COPRS NHP2 EBNA1BP2 VMP1 UCHL3 BOLA3 PCNA EMG1 UGT8 MSH2 LYSMD2 DKC1 ZDHHC6 SNX7 AMD1 STEAP1 PRPF3 SPCS1 ELOVL7 PNPT1 GMNN SEC11C GLRX2 NUP93 ETF1 HSPE1 YAE1D1 LCLAT1 C1ORF122 ARG2 ZFAND2A ODC1 GRHL3 DNAJB9 CADPS2 SRSF2 NOP14 AKR1B10 DPH2 MCM6 CD47 MRPL47 TRIAP1 BCL2L12 TAP2 FEN1 ANXA10 PPM1K CTSE CXCL11 SNHG11 IFI6 TMEM126B TTF2 KIAA1279 LAMP3 DDX60 MBNL3 LOXL1-AS1 SNRNP25 LONRF2 RFC5 PLEKHA6 C19ORF66 PPIL1 C10ORF99 MX2 IFIT5 HERC5 METTL4 TRANK1 DDX60L SAMD9 BOP1 TCTA PLK2 SLC2A10 MARVELD2 SP140L NMUR2 B3GALNT1 PANX1 C8ORF4 HMGN2 UGT2B15 HERC2P2 KRT6B SNHG20 SERPINB8 SLC25A32 NR4A1 LAMP5 PLSCR1 C4BPB ADH6 RARRES1 SFTA2 TIMM23 TRAPPC4 GATB GTF2H5 COX11 NAGK DOK3 FAIM OTUB2 STARD3NL FKBP11 RNF34 SLC35A4 ADH4 C12ORF45 TPM1 PHKG2 MRPL52 SUV39H1 MTA2 DCAF13 C16ORF62 SPINK4 BCCIP DNAJB11 PTP4A1 WDR75 CCAR1 THEM4 ADI1 CLTB MAZ MPC1 OR7E14P NBN NOP56 ATP6V0A2 UTP6 ARFRP1 APEX2 SLC26A3 ZBED5 SLC51B MUC2 GAS7 EWSR1 SLC16A14 PGP FUNDC1 CISD2 MKNK1 CYB561A3 CYP2C19 MRPS7 MRPL40 SCARA3 ZSCAN25 PSMG1 POGLUT1 ZDHHC17 SPTLC3 SLC5A6 PCGF6 HGD GSTM4 BAAT GLTPD2 GPAT3 PRMT6 PPIF MCM3 HOXB4 LPAR2 TFDP1 FAM136A RRP36 UTP11 TMEM138 POLD3 HUS1 RRS1 CCDC137 NOLC1 ZNF746 NFKBIB GPX8 MT1G TMEM19 ADGRF1 RFT1 POLR2L DUT MFSD1 USP42 NOP2 NOL6 SRPRB RPGRIP1L SFXN2 RBM14 COMMD4 GPS1 MANEAL C7ORF50 DSEL POLR3K MARC1 TMX4 SDCBP2-AS1 PCDH7 YTHDC2 RFC3 HSPBP1 HGSNAT DNAJC9 ADNP2 CCDC82 MRPL55 C2CD4A SLC35F6 SMYD5 PALLD SNORA63 SLC25A51 OXCT1 RBM12B DCDC2 SGCB LSM10 SPRTN PLK4 C18ORF54 DNAJC10 RN7SK NABP2 ATP9B TMEM220 LOC105377924 KIAA0196 ALG2 SPAG1 ENTPD7 DPCR1 NCBP1 DPH3 LINC00941 C17ORF89 MTRF1L PROSER1 FTSJ3 PLA2G10 XPO4 ZNF252P METTL1 SLC25A12 LYPD6B GPS2 LYRM4-AS1 LOC100505938 TCEANC2 TXNDC15 LOC105370333 RAD51C KIF24 FAM201A PTPMT1 NIFK ALKBH2 SCAMP3 TMSB4Y DNAJB12 TBC1D24 B3GALT6 LYSMD4 EXOG ARMC5 HRASLS5 CFAP36 TANGO2 RNASEH1 DPM2 ECE2 ZDHHC14 PLLP ALDH5A1 ST7 XKR6 AP5S1 COMMD7 RRN3P1 PDCD2 GFM1 INVS DCUN1D5 CD3EAP IDH3A 500 genes down-regulated by SARS-CoV-2 in human intestinal organoids from GSE149312 SARS-CoV-2 infection of human intestinal organoids Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/F72PQSTJV MYH9 ANO9 MOGAT2 FAM3B FCGRT MAPK3 GCC2 COL6A1 PRAP1 CSDE1 UBXN6 C1ORF115 TRIB3 HIST1H1C SMIM24 SLC22A18 NBR1 UNC93A XPNPEP2 ACSL5 NDRG1 FURIN ZBTB7B CDHR5 HSPB1 GPA33 RYBP AMN CLDN15 RBCK1 TCN2 MPZL3 MTMR11 AOC1 MID2 PLOD2 HLA-A TMEM176A PCK1 MUC17 HHLA2 SBNO1 C17ORF78 APP REN FCGBP STC2 VLDLR LIFR GBE1 ZKSCAN1 DEDD2 RNF128 EIF4B UCA1 TFF3 AK4 FAM114A1 PIGR ERBB3 SLC40A1 ECM1 DUOX2 S100A14 ELF3 SMPDL3A TOX3 PNRC1 DSG2 MT-RNR2 EPCAM TET2 SLC2A1 HIST1H2BD MALAT1 TFF1 CEACAM5 PSCA LCN2 KCNQ1OT1 SLC25A23 TMEM94 MPZL2 MAPK8IP3 GSN TGOLN2 GAA KHNYN SH3BP2 QSOX1 LRP1 SLC16A3 ITPKB GRN SLC6A6 GAS2L3 P2RX4 DDIT4 TMEM38A ELL2 LGALS1 RRAS PPARG SLCO4A1 ALOX15B FER1L4 LDHA TPI1 SCD LTBP4 CA11 PLEKHA1 G0S2 CDKN1C PBXIP1 IGFBP3 CDKN1A BMP2 KLF11 IGBP1 AXL SPINT2 SPINT1 ITGB4 TMC4 COL17A1 DSP LAMB3 SCNN1A PTK6 SEMA4B SERINC2 ZNF217 CLSTN1 TCF7L2 SORL1 SYNPR RERE KDM4B DDR1 SMARCA1 PTPN22 QPRT AOAH RETNLB KCNN4 APOBEC1 PLIN1 RNASE4 TINAGL1 RASA4 ADM TMEM171 NFIL3 PIM1 ANGPTL4 EFNA2 SPAG4 DBP TSC22D1 IRF2 IGFBP4 CHMP4B HPCAL1 EEF2 TXNIP TPPP3 CLIC3 VEGFA S100A4 PLIN2 ITM2C BTG1 GABARAP TMEM176B TAPBP CCNI IMPAD1 BNIP3 ARRDC3 TSC22D3 SH3PXD2A CAMTA2 PIM3 PSAP FXYD5 AQP1 MKNK2 STK38 PHLDA1 EIF4A2 SAT1 WDR45B CYP2S1 WASF2 CD164 SLC38A2 TMEM256 GPX4 MYZAP BNIP3L ARRDC4 DDIT3 ASCL2 EDN2 DNAH1 ZNF292 HERC3 INSR MUC1 TP53INP2 GPX3 MIR210HG BHLHE40 SERTAD2 PFKFB3 KANSL1 PDZK1IP1 WBP2 YPEL5 PAM CXXC5 AP3S1 MXI1 SUCLG2 GNA13 MXD1 FAM13A TOB1 GRB7 MKRN1 MRPS6 NEAT1 EFNA1 EPB41L4A-AS1 INSIG1 HOXA5 CREBRF MSMO1 KLHL24 NARF C15ORF48 GLCE CD46 MLXIPL ANKRD9 MSLN RAP1GAP2 PAQR5 HLA-G PCED1B MUC20 TFF2 DGAT2 SLC27A1 TFRC PELI2 ARID4A CEACAM7 SPIN4 BBX CCDC186 UCP2 ATRX GFPT1 ANKRD12 PNISR CAPN12 RSF1 SLC25A36 ETS2 CEACAM1 VAT1 LETMD1 PMM1 CA9 ENO2 SERPINA1 ALDOA ACTN1 CDA CAST ADD3 NAV1 MEX3A HSPA1L PDK1 PTPRE SMOC2 SNHG7 EGLN3 FRY LEMD1 CLK1 FHL2 PAG1 PNCK TMEM255B ADAM8 GAL3ST1 CD68 PTPRR IL10RB ITGA6 PGK1 TNFSF9 TRAF6 CXCR4 PIAS1 IFNGR2 FAIM2 SC5D IFITM10 AK3 SMURF1 UBE2R2 CALCOCO1 AHNAK C4ORF3 ASAP1 POLH ZFHX2 C14ORF93 ANKZF1 SMIM3 USP53 ALDOC TMEM123 P4HA1 GOLGA4 TMCC1 ZMYM2 PPP2R2A PGPEP1 TMEM91 PPP1R3B GPRC5C P2RY2 C16ORF58 TRAPPC6A ATP9A SMPD3 SFRP5 TAOK3 BCL6 YPEL3 DOCK6 GUCD1 TCTN3 PPARD GSDMA PRSS8 HLA-F-AS1 HILPDA CEP72 PPARA KLK1 SLC5A3 SREBF2 NPEPPS INSIG2 KRT12 ARHGAP5 KDM3A PLXNA3 LPP SENP7 ARHGAP32 CDK19 PTPRF SYT7 FXYD3 SST CYP3A5 RAB40C PDGFB CCNG2 P4HA2 CHD2 CLMN RBPJ ADIPOR2 SLC39A4 HK2 DNM2 GSTM3 ABCA2 WDR48 PHKA2 GTPBP1 SLC16A4 FMO5 ACSS2 CRAT MAP3K2 UGCG SOX4 SLC11A2 TMEM59 ERO1A ARHGEF2 FLNB NYNRIN FAM213A PFKFB4 CSRNP2 KDM5C TMEM141 FAM83A ZNF395 ESPN ZNF608 DENND4C IGF2BP2 SBF2 KDM5B ZC3H6 LOC100506548 PDK2 MACROD1 KIAA1191 DHRS3 OLFM2 KCMF1 DNHD1 ZNF609 BAZ2B LCOR PFKP DIRAS2 AHDC1 PRKAB2 LINC01559 SHANK2 SNTB1 GATA6-AS1 PALM3 DGKA BAZ2A GDI1 FNBP1 HSPA12A RAB3B MSL1 PDK3 CCDC146 LRP4 RSBN1 COL5A3 ESRG IL17RE TMEM120A MT-TV ZHX1 TMEM92 ALDH18A1 SLC6A8 RNF186 ANKIB1 WDR60 NDNF LOC105375166 ZMYND8 ADRBK2 PDE4C CCNY PRR36 PWWP2A ADRBK1 ANKRD37 COLCA2 GSAP LOC100131257 NPSR1-AS1 HIVEP3 CNNM2 DNAL1 CCDC18-AS1 OLMALINC SAV1 BRWD3 LOC554223 KDM7A LOC101927009 YPEL2 ERICH2 AATK FAM63B PHF3 PAXIP1-AS1 SLC35A3 SSFA2 FAM174A CLK3 RASSF7 FOXN3 KIAA1109 GPR146 DBN1 C1QL1 500 genes up-regulated by SARS-CoV-1 in human intestinal organoids from GSE149312 SARS-CoV-1 infection of human intestinal organoids, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/9irWSO2xm SRP19 F2RL1 TIMM8B MISP EGR1 CTSL GHITM MALL VCP NMI HRAS AADAC PKP2 TOM1L2 SLC9A3R1 GUCA2A YWHAZ HSD11B2 CXCL16 RALA ANXA3 TMBIM1 ANXA2 FABP2 VIPR1 LRRC66 ANXA11 TMEM54 RAB18 ACAA1 OAS1 AGPS PHGR1 SLC27A4 TUBA1C REG4 ANXA13 CYP2C18 EPB41L5 ABCG2 TSPAN8 FOXA1 LGALS4 TIMM10 KRT20 HSPA8 FRMD3 GUCY2C MUC13 RAB10 KALRN ARL14 ENTPD5 MYD88 LRRC1 PRPF18 TPMT ABHD3 CD55 ALDH1A3 CXCL1 KRT18 CDK2AP1 LINC01133 KRT7 RGS2 HS3ST1 KRT17 EXT1 IL33 MT-ND1 MT-RNR1 GCNT3 S100P SERPINB5 HOPX MT1E METTL7B PPL BCAS1 MT-ND2 KRT19 RND3 SLPI GPRC5A TACSTD2 AGR2 KRT8 PLEKHG1 MYO5C COPS9 FTL CD24 THBS1 HBEGF SF3B4 CORO1B LTBR RHOB MYOF FLVCR2 PLBD1 CEBPA NLN AREG IL18 LGALS3 NME1 NECTIN2 PADI2 TBC1D2 ESRP2 CXCL8 AKR1C3 CAMK2N1 MMP1 KLF13 GADD45B ACTB EDN1 CYCS LAD1 LYPD3 GJB3 EPN3 CLDN4 FGFBP1 PSMD6 CNKSR1 WWC1 CAPN1 JUP CEP170B PLCD3 C1ORF106 SULT2B1 KRT80 GIPC1 SPDEF RHOD EREG KITLG CLU TMSB4X DKK1 HNRNPK EFNB2 ELF4 UPP1 PSMA3 TMEM164 SLC16A5 CBX4 CXCL3 IL1R2 IL1RN CA13 PLAC8 AAK1 SOCS3 TNFRSF12A ARC AIM1 FOSL1 F3 ACKR4 IER2 EPAS1 TNNC1 HNRNPM ACTG1 SGK1 CRYAB BAG1 MYL12B DUSP1 TMCC3 CAPZB ID3 ARL2BP KLHL5 HPGD CLIC5 GDPD3 CA2 SLC34A2 CTGF FABP5 VIMP MAT2A ALDH1A1 TAGLN MRPL20 PSMB5 PSMD3 ABRACL QDPR NDUFB3 SMIM15 FDX1 LAMTOR1 CRELD2 S100A16 DNAJA1 RBM3 ANXA1 SERPINB6 LXN ATP2B1 PPIC VCL S100A10 CD9 GEM HSPA6 PPP1R15A SULT1E1 MAPRE3 AMOTL2 FLRT3 BAMBI SERTAD1 CHAC1 FOSB SELT POLR2G NQO1 PSMD1 ATP6V0D1 PSME3 DPP3 ICT1 ORMDL2 MCUR1 TMEM14A GSKIP EMG1 PSMC1 TRAPPC3 ZDHHC6 ZNF593 SNX7 ACTR10 TNFRSF21 PRPF3 MICU2 ETHE1 PSMD14 LACTB2 SEC11C NAA10 GLRX2 HSPA1A YAE1D1 C1ORF122 C3ORF38 ARG2 SLC25A46 ZFAND2A ODC1 GRHL3 SGMS2 RHPN2 PIP5K1B ID1 AKR1B10 ID2 CSRP1 RWDD4 MRPL47 PTS SLC6A9 TAP2 ANXA10 ASCC3 RASD1 CTSE IRAK2 ACTN4 TRNP1 SLC20A1 KIAA1279 SNRNP25 PET117 C19ORF66 C10ORF99 MIR22HG DNAJC3 LIPH CORO2A TCTA LAMC2 PKIB CHUK XRCC4 EMP1 MB21D2 TGS1 FOXC1 PLK2 DUSP4 NMUR2 FAS SH3KBP1 FUT4 BLZF1 C8ORF4 RSU1 CLIC1 MYL9 RAP2B CALM2 UGT2B15 ARMCX1 KRT6B GRAMD1B KIAA0040 PHLDA2 SERPINB8 SLC25A32 NR4A1 DSC2 ANO1 PLSCR1 C4BPB SFTA2 CA1 HSPA1B PSMC4 TIMM23 GLRX3 PSMD9 RAB35 FTSJ1 NAGK FAIM RABIF HMOX2 SQRDL PSMC3 TNFAIP1 TMEM9B TPM1 ABHD16A ALDH3B1 ANXA4 CDC42SE1 ABHD5 NIP7 C16ORF62 EPHA2 BCCIP CLDN1 DNAJB11 NT5C2 DNTTIP2 PTP4A1 ADI1 CLTB MPC1 OR7E14P AGMO ATP7B KLK10 OCLN DHX9 SLC26A3 MUC2 NAT2 EWSR1 ID4 TXNRD1 PGP RAB32 BANK1 ATG4A LRRC59 PRR5L CYP2C19 CTNS C10ORF54 UBR7 SPTLC3 GCLM AKR1C2 NAT1 BAAT AKR1C1 NIPAL1 LMO4 TRAF4 SFPQ GPAT3 PNO1 RRP36 TRMT6 HUS1 NFKBIB SLC35B1 MT1G MGST3 SLC25A20 FAM96B AHCYL2 CLDN23 KRT23 ADGRF1 POLR2L SSBP1 MFSD1 ADGRG6 CHCHD3 USP42 MAX ABTB2 FSTL3 GPS1 DSEL SLC22A18AS MICAL2 MFSD2A MIER3 LOXL4 SLC35D1 NABP1 GPD1L HSPBP1 HGSNAT LGR4 DNAJC9 TDG BICC1 PHACTR2 COMMD2 USP38 RAB27B SLC35F6 SLC20A2 PALLD NOP16 SSPN MPRIP HIGD1A PID1 SLC41A2 REXO2 ARPC5L ATP5F1 STRIP2 DUSP14 BTBD10 DENR MMP28 FSIP2 RN7SK GTF2A2 ATP9B MED27 LOC105377924 KIAA0196 ALG2 CCL15 WTH3DI UFD1L SPAG1 MT-TM ENTPD7 DPCR1 MOB3B WFDC21P RBM45 NHSL1 LOC105369340 EPT1 SNAP23 MARCH3 OVOL2 ZNF271P MTRF1L DDX47 SERAC1 MRM2 NIFK PLLP COMMD7 GFM1 IDH3A EXOC6B LCMT2 MT-TL1 PLPP1 ZNF561 LOC102724094 INAFM2 C15ORF41 PRKCDBP NSUN2 CCDC51 FBXO28 CLOCK 500 genes down-regulated by SARS-CoV-1 in human intestinal organoids from GSE149312 SARS-CoV-1 infection of human intestinal organoids, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/9irWSO2xm ANO9 MOGAT2 CEP250 ERMP1 FCGRT COL6A1 TM6SF2 PRAP1 SUN2 SMOC1 C1ORF115 TRIB3 CREB3L3 RNF24 SMIM24 TMEM97 PFKL NBR1 UNC93A ACSL5 SLC5A1 PRRC2B NDRG1 HLA-B KCNQ1 CDHR5 CENPF CLDN15 SLC15A1 TCN2 MPZL3 PLOD2 FABP6 HLA-A TMEM176A ISYNA1 B2M PCK1 MEP1A HHLA2 AKAP9 C17ORF78 APP GOLGB1 TKFC REN REEP6 FCGBP STC2 DHTKD1 ZBTB44 VLDLR FGFR4 GBE1 ALDH6A1 ZKSCAN1 UNC119B TFF3 AK4 TNFSF10 PIGR SLC40A1 ECM1 FGFR2 AQP5 FAM117B DUOX2 NFAT5 GATAD2B SMPDL3A PNRC1 KIAA1324 SLC2A1 HIST1H2BD MALAT1 BDP1 TFF1 LCN2 KCNQ1OT1 SYBU TMEM94 MPZL2 MAN2B1 LGALS3BP GSN GRINA TGFBI KHNYN QSOX1 LRP1 SLC16A3 GRN SLC6A6 GAS2L3 P2RX4 DDIT4 TMEM38A TMTC2 LGALS1 MCM2 KIF14 ASPM RNASE1 SLCO4A1 GAPDH LDHA TPI1 SCD ANG CA11 FGFRL1 FAM131B CDKN1C COLGALT2 PBXIP1 IGFBP3 ZFP36L1 KLF11 PIK3IP1 AXL TMC4 COL17A1 SOX9 INPP5D HIF1A SOX12 SORL1 SYNPR PACS1 ZNF385A ULK1 SMARCA1 QPRT DENND1C KIF22 AOAH LCK CENPH KCNN4 CENPE APOBEC1 CIDEC PLIN1 MAB21L3 TMEM143 RNASE4 PML TINAGL1 RASA4 ADM TMEM171 NFIL3 ANGPTL4 SPAG4 DBP TSC22D1 BTG2 DPYSL2 IGFBP4 HPCAL1 SIPA1 TXNIP TPPP3 CLIC3 ST5 VEGFA PLIN2 LUC7L3 BTG1 LYZ TMEM176B TAPBP SLC12A2 CCNI BNIP3 ARRDC3 PDCD4 CD74 TSC22D3 FUCA1 CAMTA2 PSAP FXYD5 RBBP4 IL2RG RTKN2 MKNK2 GNS EIF4A2 IVNS1ABP SAT1 WDR45B CYP2S1 HAUS4 SLC38A2 MARC2 BNIP3L ASCL2 EDN2 OLFM4 ZNF267 ZNF292 SLC38A11 MUC1 HOXB8 SEZ6L2 CALB2 MIR210HG BHLHE40 PFKFB3 KANSL1 MSL2 PDZK1IP1 YPEL5 LMAN1 PTMA SLC39A10 FAM60A KIAA0430 MXI1 RLF TMEM245 FAM13A SYT13 GRB7 MKRN1 NEAT1 HIST1H4C EFNA1 EPB41L4A-AS1 VEGFB PGM1 CREBRF KLHL24 C15ORF48 CEMIP LGR5 GLCE CDCA7 PCYOX1L MLXIPL RASA1 EFNA3 STXBP1 NUDCD3 MSLN GMDS RAP1GAP2 HLA-G PIGZ TFF2 DGAT2 TNFAIP8L1 SLC27A1 TFRC PTMS PELI2 VNN1 SLC51A AHSA2 GOLGA8A PIGL CCDC28A CEACAM7 HAUS6 MLEC TMEM107 BBX PIK3R1 TNRC6B UCP2 ATRX IGF1R SH3BP4 ANKRD12 CEP290 BOD1L1 PNISR THOC2 CAPN12 RFX7 SLC25A36 ETS2 CEACAM1 GPT2 LETMD1 PMM1 TRIB2 CA9 ENO2 SERPINA1 ALDOA CDA CDKN1B AKAP11 ROCK1 TRAF5 MEX3A HSPA1L ATF7IP PDK1 DOK7 SMOC2 SNHG7 EGLN3 FRY LEMD1 CLK1 PAG1 PNCK ADAM8 GAL3ST1 PTPRR PGK1 PIAS3 CXCR4 IFNGR2 FAIM2 SC5D GDE1 CALCOCO1 C4ORF3 ORAI3 MPP3 ASAP1 C14ORF93 ANKZF1 SMIM3 USP53 ALDOC TMEM123 P4HA1 GOLGA4 TMCC1 ATXN1 PGPEP1 SYNE2 ATP9A POLR2A SFRP5 EPHB3 DBNDD1 BCL6 YPEL3 FARP1 RPS6KA2 GSDMA PRSS8 TNFRSF11A HILPDA PPARA KLK1 SLC5A3 INSIG2 KDM3A SEMA6A KMT2A USP28 PLXNA3 VWA2 CDK19 C9ORF152 SYT7 PROM1 EHMT2 CYP3A5 SMC4 PDGFB FXR1 P4HA2 CLMN RBPJ FOXA2 PRKCG SLC39A4 HK2 DNM2 GSTM3 WDR48 PHKA2 CYP4X1 CRAT PPP1R9B SOX4 PPP1R1B SLC11A2 CRTAP ERO1A AHCYL1 NYNRIN PFKFB4 C6ORF223 DHCR7 KCNMB4 NRM HES6 PLEKHB1 GALNT10 NFIX ZNF395 ESPN CPD FHIT SBF2 ZC3H6 LOC100506548 PDK2 SNX25 GRAMD1A NME4 MOSPD3 SLC50A1 LHPP KIAA1191 DHRS3 OLFM2 ECH1 GPATCH8 PHF21A PFKP PAFAH1B3 C11ORF68 BCKDHA RGMB PRKAB2 LINC01559 ZSCAN16-AS1 SNTB1 PALM3 HDAC11 ECI2 ZFC3H1 KIAA2026 INO80D HSPA12A PTPRN2 PCMTD1 PDK3 CCDC146 MGAT5 LRP4 KIF1B WDR19 ESRG ZAK MT-TV MLH3 TMEM92 ALDH18A1 SLC6A8 RNF186 WDR60 NDNF YBX2 ZMYND8 ADCK3 ADRBK2 ITPR2 ADRBK1 LOC729348 ANKRD26 PALD1 C8ORF58 ANKRD37 FAM193A COLCA2 LOC113230 ZMYM3 GSAP LOC100131257 NPSR1-AS1 ARHGEF40 HIVEP3 GPR153 SORBS1 DNAL1 HCG8 CCDC18-AS1 OLMALINC ELF2 BRWD3 PAXIP1-AS1 CLK3 FOXN3 DBN1 PHLPP1 SRGAP2B PPP1R3E CRHR1-IT1 ATP2B4 HMBOX1 PCAT6 NR6A1 ZNF511 CEP295 HSD11B1L LOC284023 CCSER2 ASIC1 METTL15 500 genes up-regulated by SARS-CoV-1 in human intestinal organoids from GSE149312 SARS-CoV-1 infection of human intestinal organoids, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/46uHWBQK5 SLC36A1 SLC10A2 TIMM8B HSP90AB1 XPO6 SLC17A4 HYOU1 ANPEP CTSL PRIM2 SPTAN1 NMI DGAT1 EXOSC8 GUCA2A RBP2 ACE2 PPT1 NGDN MTTP SLC6A19 SLC46A3 MEP1B HSP90AA1 ALG5 RAB18 SLC7A9 AGPS PHGR1 SLC27A4 DNMT1 TUBA1C REG4 ANXA13 CYP2C18 FABP6 NDUFB9 RAE1 TIMM10 DHRS11 ITM2A ALDOB EDEM3 UBXN8 HSPA8 TMEM253 EI24 CISD1 CD55 ATF5 NCOA5 TBCB DANCR MT2A KRT18 STOX1 RGS2 MT-ND1 NR4A2 SERPINB5 HOPX MT1E KIF21A METTL7B MT-ND2 CYBRD1 PRSS16 ATOX1 GPRC5A AGR2 KRT8 MYO5C COPS9 CD24 PGD SF3B4 GPD1 FLVCR2 EXO1 ZWINT CLSPN TK1 TROAP PLBD1 E2F2 CDCA5 MT1F MTCH2 KIAA0895L RRM2 PAQR4 E2F1 BIRC5 NETO2 NME1 CEP55 CDC20 TRIP13 CENPU MKI67 SORT1 CDC45 DTL ARNTL2 AIMP2 MYBL1 PKD2 CYP4V2 FOXM1 SRSF1 CEP170B MYO19 SPDEF WDR7 KITLG DKK1 MSX2 NUCB2 IPO9 DGCR8 TCF19 CHAF1B IQGAP3 HELLS OIP5 MCM5 AUNIP ZWILCH CENPM NDC80 KIAA0101 PSAT1 POLE2 GINS1 IL1R2 IL1RN CA13 MLKL PARP9 WARS ACKR4 C1ORF56 HNRNPM TUBA1B SGK1 HPGD CLIC5 GDPD3 CA2 FABP5 H2AFZ ALDH1A1 MRPL20 TUBB SMIM15 LAMTOR1 CALR TEX261 DNAJA1 CD36 ATP2B1 ANAPC5 NXF1 SSR3 NDUFB10 NOS2 ZNF35 TBC1D30 CHAC1 HAT1 RRM1 PSMD1 SEC61A1 SRM CNOT10 ATP6V0D1 SLC25A11 GALNT7 TIPIN NHP2 EBNA1BP2 NOP58 PCNA EMG1 MSH2 DKC1 ZDHHC6 TMEM185B AMD1 STEAP1 PRPF3 PSMD14 SPCS1 NOL11 TMPO ELOVL7 USP1 GTF3C6 GMNN SEC11C NAA10 GLRX2 NUP93 LCLAT1 GEMIN6 C1ORF122 ARG2 ODC1 GRHL3 DNAJB9 FKBP4 SRSF2 ZDHHC23 AKR1B10 DPH2 SRSF6 CSRP1 MCM6 URB2 MRPL47 TRIAP1 TRA2B SNRNP40 TATDN2 LRRC14 FEN1 BRINP3 ANXA10 AGMAT CREM MOCOS TAPBPL ASCC3 NRARP CTSE KATNA1 IARS TMEM126B FAM111B KIAA1279 MBNL3 SNRNP25 RFC5 PPIL1 C10ORF99 MIR22HG METTL4 TRANK1 KCTD12 TCTA ACOT7 TYW1 CHUK XRCC4 PLK2 NMUR2 SH3KBP1 BPGM HMGN2 UGT2B15 MAST3 KRT6B NR4A1 PLA2G4F PLSCR1 C4BPB ADH6 POLR1A RARRES1 SFTA2 PSMC4 TIMM23 PSMD9 COX11 GLE1 NAGK USP14 FAM111A GNPNAT1 CPPED1 STARD3NL FKBP11 DDX56 ALG3 HM13 PSMC3 RNF34 SLC35A4 ADH4 C12ORF45 TPM1 APRT ALDH3B1 ABHD5 AVEN SUV39H1 C16ORF62 SPINK4 SLC10A7 CLDN1 DNAJB11 PTP4A1 CCAR1 WDR43 THEM4 FIZ1 ADI1 CLTB IPO13 SMPD1 MPC1 NBN ITGB2-AS1 NFKBID PMM2 NOP56 ATP6V0A2 UTP6 PSMD2 ARFRP1 APOC3 APOB SLC51B MUC2 SENP1 TTTY15 RING1 EIF5A2 PGP BANK1 LRRC59 CYB561A3 CYP2C19 CTNS MTHFD1 PSMG1 UBR7 PTBP1 POGLUT1 SLC5A6 GSTM4 BAAT GLTPD2 SFPQ GPAT3 PRMT6 PPIF MCM3 TFDP1 PNO1 FAM136A TAF1B PRPF4 TRMT6 POLD3 HUS1 HNRNPAB IPO4 NOLC1 SDHAF3 SLC35B1 GPX8 TXNDC9 MT1G TIMM17A AHCYL2 TMEM19 IMP3 TIMMDC1 ADGRF1 RNASEH2C RFT1 POLR2L BCL7C MFSD1 ATP5B NOP2 NOL6 SRPRB ZNF77 SFXN2 RBM14 COMMD4 GPS1 C7ORF50 MAOB LOC100294145 MARC1 MICAL2 REV3L ENDOD1 SLC35D1 YTHDC2 CRNKL1 SRGAP3 IGFBPL1 RFC3 HGSNAT DNAJC9 ADNP2 SERTAD4 BICC1 TRMT10C USP38 RBMXL1 GPATCH4 RRP15 HGH1 SMYD5 FAM104B TMCO1 FANCE RPP25 SSPN BORCS8 OXCT1 PID1 REXO2 AMT DDX23 DCDC2 SPRTN DENR C18ORF54 DNAJC10 FSIP2 RN7SK GTF2A2 ATP9B PYCRL TMEM220 C2ORF88 LOC105377924 C9ORF40 KIAA0196 ALG2 SPAG1 MT-TM ENTPD7 DPCR1 MOB3B MRPL19 NUP35 BORCS7 NCBP1 SNAP23 ZNF271P MCM8 PROSER1 LOC644794 MRM2 LYAR PLA2G10 XPO4 ZNF252P LYPD6B GPS2 LOC100505938 RAD51C ALKBH2 TMSB4Y HRASLS5 DPM2 PLLP ST7 COMMD7 GFM1 CD3EAP IDH3A EXOC6B MT-TL1 C15ORF41 STRIP1 MUC6 C14ORF142 TPCN2 EIF2B2 CTBP1-AS2 METTL13 MT-TI UTP14A LINC00852 FKTN SEPT7P2 IMP4 ZNF215 CDIP1 NAT10 ADCK1 RAB12 TMEM98 CLP1 BLM PUS1 POLR1B ZNF124 LOC101927503 MAGEF1 GNL3L PRPF31 500 genes down-regulated by SARS-CoV-1 in human intestinal organoids from GSE149312 SARS-CoV-1 infection of human intestinal organoids, effects can be compared to those of SARS-CoV-2 Source paper: https://pubmed.ncbi.nlm.nih.gov/32358202/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/46uHWBQK5 MYH9 ANO9 FAM3B FCGRT GDF15 COL6A1 PRAP1 TRIB3 NPC2 MYO1D TMBIM1 SLC22A18 NBR1 UNC93A ACSL5 CDX2 NDRG1 HLA-B ZBTB7B KCNQ1 HSPB1 GPA33 GOLGA2 RBCK1 MPZL3 KIAA2013 MID2 PLOD2 HLA-A TMEM176A B2M PCK1 MUC17 TRIM31 HHLA2 C17ORF78 APP REN REEP6 FCGBP STC2 VLDLR LIFR FGFR4 GBE1 ZKSCAN1 FZD5 ZFAND1 DEDD2 RNF128 UCA1 TFF3 FAM114A1 TM4SF1 ERBB3 SLC40A1 ECM1 MT-ND6 NFAT5 S100A14 ELF3 LURAP1L SMPDL3A TOX3 PNRC1 DSG2 EPCAM TET2 SLC2A1 GADD45A HIST1H2BD MALAT1 TRIM29 CEACAM5 LCN2 ABCA1 KCNQ1OT1 TMEM94 MPZL2 GSN TGOLN2 KHNYN SH3BP2 QSOX1 LRP1 SLC16A3 TKT ARAP1 HLA-E GRN SLC6A6 P2RX4 DDIT4 IGFBP2 TMEM38A TMTC2 LGALS1 RRAS PPARG SLCO4A1 ALOX15B LDHA SCD CA11 PLEKHA1 G0S2 CDKN1C SOX13 IGFBP3 BMP2 ZFP36L1 KLF10 IGBP1 CDH1 SPINT2 SPINT1 CLDN4 CHMP4C ITGB4 TMC4 COL17A1 DSP LAMB3 SCNN1A ENTPD2 PTK6 SEMA4B SERINC2 IRF6 ZNF217 EPHB4 SOX7 INPP5D CD63 TCF7L2 DACT2 SYNPR ULK1 SMARCA1 PTPN22 QPRT DENND1C AOAH CCL20 KCNN4 APOBEC1 TMEM45B CYP1A1 PLIN1 PRSS22 HAS3 RNASE4 TINAGL1 TNFRSF12A RASA4 GBP2 ADM TMEM171 NFIL3 PIM1 ANGPTL4 RTN2 SPAG4 DBP TSC22D1 IRF2 KLF4 IER3 IGFBP4 HPCAL1 SIPA1 TXNIP TPPP3 CLIC3 JUNB VEGFA S100A4 PLIN2 BTG1 LYZ NR1D2 GABARAP LITAF SERPINB9 TMEM176B TAPBP CCNI BNIP3 ARRDC3 TP53INP1 TSC22D3 RPS9 PIM3 PSAP FXYD5 MKNK2 PHLDA1 EIF4A2 SAT1 WDR45B CYP2S1 WASF2 CD164 SLC38A2 GPX4 BNIP3L ARRDC4 DDIT3 ASCL2 EDN2 ZNF292 CLSTN3 HERC3 INSR CMIP FBXL16 CALB2 MIR210HG FAM161B BHLHE40 MAFF SERTAD2 PFKFB3 PDZK1IP1 YPEL5 PAM CXXC5 AP3S1 FAM60A AMIGO2 MXI1 MXD1 FAM13A TOB1 MRPS6 KLF7 EFNA1 EPB41L4A-AS1 INSIG1 PRR15 HOXA5 MSMO1 SQLE KLHL24 TTF1 C15ORF48 CEMIP GLCE MLXIPL RASA1 ANKRD9 REL RAP1GAP2 LMTK3 PAQR5 HLA-G PCED1B CHAD TFF2 DGAT2 SLC27A1 AARS PELI2 MT1X CCDC28A CEACAM7 SPIN4 BBX CCDC186 C1ORF210 UCP2 GFPT1 CAPN12 SLC25A36 ETS2 CEACAM1 LETMD1 PMM1 CA9 ENO2 SERPINA1 ALDOA EIF1 CDA ADD3 MEX3A HSPA1L PDK1 SMOC2 SNHG7 EGLN3 FRY LEMD1 XYLT1 CLK1 FHL2 PAG1 PNCK TNFRSF10D ADAM8 NR1D1 GAL3ST1 RSPH1 CD68 DUOXA2 PTPRR GABRB2 IL10RB SIAH1 ITGA6 PGK1 TNFSF9 IFNLR1 UBE2B RIOK3 SH3BP1 CXCR4 TNFRSF1B GNRH1 FAIM2 SC5D IFITM10 GDE1 GID8 SMURF1 AIG1 CALCOCO1 CMAS C4ORF3 MPP3 ASAP1 TSPAN5 ANKZF1 SMIM3 USP53 ALDOC TMEM123 P4HA1 TMCC1 ZMYM2 PPP2R2A ATXN1 TMEM91 TRAPPC6A ATP9A DBNDD1 BCL6 YPEL3 DCAF5 NFATC4 DOCK6 GUCD1 GSDMA PRSS8 TNFRSF11A HILPDA PPARA KLK1 SLC5A3 MTHFR SREBF2 NPEPPS INSIG2 KDM3A PLXNA3 SENP7 PTPRF SYT7 FXYD3 SST CYP3A5 PDGFB CCNG2 P4HA2 CLMN RBPJ FOXA2 PROX1 ADIPOR2 HK2 DNM2 USP49 ABCA2 WDR48 PHKA2 SLC16A4 SLC29A2 ACSS2 CRAT UGCG LNX1 SOX4 ING1 SLC11A2 TMEM59 ERO1A OXR1 PNKD NYNRIN FAM213A HECA FBXO2 LYST KDM5C OSBPL7 HES6 TMEM141 NFIX ZNF395 ESPN DENND4C C11ORF54 SBF2 KDM5B ZC3H6 IFRD1 PDK2 ZNF703 RNF43 ZMIZ1 IDS CDK18 OLFM2 KCMF1 DNHD1 PFKP PHF13 RGMB SNAPC3 AHDC1 PRKAB2 LINC01559 SNTB1 PALM3 HDAC11 FNBP1 HSPA12A RAB3B PTPRN2 PCMTD1 PDK3 CCDC146 LRP4 LINC00506 ESRG MT-TV TMEM92 SLC6A8 RNF186 CNNM1 LOC105375166 ZMYND8 ADRBK2 PDE4C CCNY LOC729348 PALD1 C8ORF58 ANKRD37 COLCA2 GSAP LOC100131257 NPSR1-AS1 ARHGEF40 HIVEP3 GPR153 DNAL1 OLMALINC SAV1 KDM7A FAM63B SLC35A3 FOXN3 GPR146 C1QL1 SRGAP2B HMBOX1 PCAT6 LOC284023 CCSER2 CD27-AS1 ZNF155 BLACAT1 PHF1 ACSF3 LINC00887 RUFY2 FLJ23867 POLL RAB11FIP4 CLEC4GP1 APOLD1 ZNF213 TSNARE1 LINC00675 SRP14-AS1 DDX3Y ZNF615 PRKX TLE2 Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection Hits from a COVID-19 CRISPR screen CTSL ACE2 SMAD3 SMARCA4 ACVR1B JMJD6 SMAD4 SMARCA5 PCBD1 ATRX SMARCE1 DYRK1A SIAH1 PIAS1 HIRA SH3YL1 ARID1A KDM6A UBXN7 PHF6 DPF2 PHIP TMX3 RAD54L2 PIAS2 CABIN1 DOLK 660 genes upregulated by cystine and theanine in IAV-infected mouse spleen We demonstrated the molecular mechanism of the antiviral effect of orally administered cystine and theanine (CT) and further explored how CT acts on the dysregulated cytokine and immune response characteristic of COVID-19. IL1B UHRF1 RBL1 TRIM59 PRIM2 GHITM COMT CAPN2 KPNA2 PCK2 TSPO RHOA EPB41 PDZD11 ZCRB1 SLC30A9 EPS15 STOML2 AP2M1 HSP90AA1 TUBA1A POLA1 PSMD4 UBQLN1 TUBA1C PSMC6 CTSD PABPC4 NUCB1 MARK3 ST3GAL4 RAD23A TMEM176A ABCG2 BRCA1 PABPC1 POLA2 STOM USP15 NUP85 ISG15 USP7 FBXO9 FBXO3 SLC25A39 GLO1 ASF1A NSMCE4A VAMP8 KLF1 FAHD1 ADK PSMA2 ATP6V1G1 DCTN2 RPS17 CDK2AP1 CEBPD IFI27 HIST1H2BC COX6A1 GADD45A CKS2 ISG20 LCN2 STARD10 CCND1 SRRT OGDH PDIA6 STMN1 HS1BP3 GRINA GNB2 DNAJB2 BSDC1 LMNA TKT DDB1 MRC1 CCT5 TOP2A PNP MRPL37 CDCA8 CCNA2 LMO2 TK1 EZH2 LMNB1 CCNB2 CDKN3 CREG1 GLRX IGHG1 SCPEP1 MTCH2 MCM2 KIF2C SDHD AURKA DLGAP5 CAPNS1 BUB1 RRM2 ITSN1 CDK1 CDC6 BIRC5 MCM10 GAPDH HEBP1 KIF11 CCNB1 ANLN NCAPH GRHPR CDC20 KIF23 TTK PRDX3 HP MKI67 DTL TYMS ZFPM1 CAMP AZIN1 AUH TRAM1 MARS KLF10 CKS1B COL1A1 TRAK2 GADD45B ELANE CTSG LTF JMJD6 AGRN SLC7A5 MAP2K3 DCK PRC1 BTRC TAB3 SMC2 RSAD2 CDC25C E2F8 UBE2T CENPA MIS18BP1 FIGNL1 CD3G KIF22 TCF19 GATM HIST1H3D ECT2 NUSAP1 CKAP2 MCM5 IFIT1 RAC2 H2AFX MAD2L1 CCNF HMGB2 KCNN4 INCENP RAD51AP1 S100A9 PSAT1 SFT2D1 CDT1 CCR1 CD5L USP18 ALAS2 SLC4A1 SNCA TIMELESS TINAGL1 GCH1 PIM1 UBE2L6 TSC22D1 BTG2 TSPAN13 YBX1 YBX3 MAP1LC3B BAG1 PPP1CB RAC1 EIF3G GSTM5 COX17 SYF2 ST5 CYB5A WBP5 H2AFZ COX7A2 PLIN2 NACA ALDH1A1 PSMC2 PRDX5 NDUFB11 PCNP OAZ1 NDUFA5 RGCC CDK16 TYROBP SOD1 LAMTOR1 CCT3 ATF4 TALDO1 ROMO1 NDUFC1 PQBP1 MRPL28 FXYD5 AQP1 MPC2 MXD4 PIGQ DNAJB1 WNK1 STK38 ANXA1 UBE2V1 LRG1 VPS26A NDUFV2 VBP1 GTF2B ANAPC5 SSR3 BNIP3L DEK ANK1 POU2F2 PPP1R15A PGLYRP1 HMGN5 TAF1D FOXO3 ANP32A UBE2A UBE2S PRR13 MOB1A PDZK1IP1 SEP15 HAT1 HMGB3 ISCA2 WBP2 RRM1 NDUFAB1 SLC29A1 PTTG1 PSMD13 TMX1 PA2G4 PSME3 TIPIN AHCY NHP2 LSM7 VMP1 NPM3 UQCRQ ANP32E PCNA MRPL16 ATP5L MGLL BUB3 ACTR10 RFC4 PSMD14 TMPO UQCRH SSR2 CCT7 CDC16 USP1 GMNN NAA10 ERH ETF1 RPN2 PFKM CDK4 MXI1 MRPL18 FAM117A ODC1 NUDT9 USP10 RUVBL2 NCOA4 FKBP4 HSPD1 PIP5K1B MKRN1 RANGAP1 SRSF2 MNS1 TBL1XR1 SRI MEA1 KLF3 CSE1L ATP5E CDCA7 CD47 IFT46 RPA3 SLIRP VAMP5 FEN1 ASNS S100A8 CSF3R MARCH5 CTSE TSPAN33 TFRC NFE2 CDKN2C LBR MADCAM1 APCDD1 MCM4 MCM7 TMEM56 SEC62 LIG1 HNRNPA2B1 CBX5 TOP1 NDUFS1 GINM1 EIF2B4 CARM1 LPCAT1 SCT ORC6 RALBP1 ANP32B NAPA MTF2 BPGM BLZF1 GTPBP2 U2AF1 MSRB1 UQCR11 EIF1 PRTN3 HMGN2 MPO CASP8 PPP2R5C CALM2 ADAM10 SESN1 CENPV PIGA ITLN1 IGHM TUBB3 TAL1 GFI1B PRDX2 RAD21 KPNA1 COPZ1 COQ9 SLC31A1 ACP1 LYL1 UBA2 UBE2H IGF1 AGO2 PRMT1 CLCN3 BSG ARRB1 HARS ERP29 PLEKHB2 UBAP1 TXN2 USP5 ARAF NECAP2 HMBS SNW1 FCF1 HAGH PSMC3 ATG12 YIPF4 UBE2R2 COX6B2 PNPO ALAD ARL8B CMAS AKIRIN2 CAPZA1 BUD31 BECN1 ABHD5 CCS MID1IP1 NDE1 MFF MRPL52 ST3GAL5 ASAP1 HNRNPUL2 MTA2 SETD8 DNTTIP2 CPSF3 RIOK1 PMF1 RALY PRADC1 SLC37A4 CMC2 ACSL1 YPEL3 TPP1 PQLC1 SLC38A5 UROD CTTN SIVA1 NASP XRCC6 FDFT1 RNASEH2B RAB6A OTUD5 AMPD3 GCLC SOWAHA FXN CDC34 EWSR1 ASXL1 SUZ12 SMC4 DTYMK CUL4A RHD GOLPH3L RFC1 LRPPRC PPP2R5A ABCB4 GCLM NFYA MYB RBM17 MT2 PPIF MCM3 EPOR TFDP1 PSMA5 CDKN2D PPM1G RBM38 SUDS3 LSM4 CDCA4 BYSL IFRD2 TOPBP1 UBP1 FBXW2 TXNRD2 ATF1 TXN1 HMGCL MGST3 SFXN1 CYB5R1 JOSD2 IFI27L2A WFDC21 MT1 TUBGCP4 FAM213A RNASEH2C SLBP F11R MAX LPIN2 DNAJB6 RBM14 RPA1 SSX2IP LPCAT3 TOM1L1 IBTK DNAJC9 CDR2 STX2 DCLRE1A A4GALT HTRA2 LONP1 UBE2O ATPIF1 HSDL2 EVI5 TUG1 OTUD4 LSM3 MRPL50 WBP1 NUDT3 PPOX BCAP29 IGTP IRGM2 TUBB5 SLFN4 SAA3 PSMD12 ACADL 1810058I24RIK CHIL3 ISOC1 H2-T24 PNRC2 CD24A WDR26 NGP MRPS18A MED20 CCNDBP1 PITHD1 PLK4 ZC3H3 SMARCC1 MINOS1 TSFM VOPP1 PDS5A NIFK PRKCDBP CLP1 FAM220A RHAG GM15455 NDNL2 XPO7 GM10257 CPOX BRIP1OS UROS GYPA PCYT1A NMT1 SPECC1 SMAP1 GM29779 GM37013 NIT1 MRPS28 CNOT6L 2310036O22RIK CD59B CAR1 IGHG LOC102641332 AMD-PS4 GM4246 GM15421 1700037H04RIK LOC102641947 ATP5O LY6G CES2G RAD50 PTDSS2 VAMP4 CAR2 6430706D22RIK PLK-PS1 LSM8 IFITM6 FYTTD1 GM10651 WDR61 PSME4 EIF4A3 GM10177 UBAC1 ISCA1 C330027C09RIK FAM46C ARIH2 PLA2G12A GM11336 GM15151 GTF2F1 EIF1AX STX5A MRPS10 IPO11 SMIM11 KIF4 CD59A PPP6C GM9706 TIMM22 0610010K14RIK TCEB3 BC002163 SPPL2B 1300017J02RIK HEMGN EPB42 MRPS24 CMC4 GM7367 DOCK9 GM6654 LOC102641872 RNF38 IGKV10-95 ANKRD46 MZT2 TBCEL 1190002N15RIK SLMAP MPP1 DOK1 HELB PPP2R4 NUDT4 GM5879 2810417H13RIK LOC102643093 630 genes downregulated by cystine and theanine in IAV-infected mouse spleen We demonstrated the molecular mechanism of the antiviral effect of orally administered cystine and theanine (CT) and further explored how CT acts on the dysregulated cytokine and immune response characteristic of COVID-19. MYH9 CD79B IGSF8 RAD23B IDE CCL5 TCF12 MVP VCAM1 UBD DDX5 MOGS AKAP8 TBK1 YWHAZ RRP9 MACF1 IFITM3 RNF2 GOLGA3 AP3B1 PKM EPS15 UBA1 KLF6 SIRPA GPX1 CFP TUBA4A TRAF3 UBAP2L HGS SRPK2 B2M FBN1 MYCBP2 CD7 G3BP1 FERMT3 MARK2 MAP3K1 DIAPH1 CXCL9 CASP3 FRMD8 GFER MX1 MYD88 TOP2B MAPK1 GRB2 PGM2 LYPLA1 LYRM2 DOLPP1 POLRMT TLN1 LIFR RBM39 ATP6V1B2 ZRSR1 CD55 ZFP106 MYO6 UNC119B RNF167 MGAT1 PLEKHO1 ISLR LCP1 PIGR HIST1H2AL RPS12 RBPMS ZFP1 S100A14 NFIB PAWR TPST1 RPS27 MDM2 STIM1 ITPK1 ARF3 LSP1 ADCY7 USF1 PRKCSH INPPL1 TOR3A TM9SF3 AKT1 PTK2B SEC24C FKBP8 SHKBP1 ITGB5 LRP1 KCNAB2 TMED9 TOLLIP SCAMP2 LPL CLCN4 DDIT4 ANXA5 ACVRL1 RENBP IRF5 H1F0 ROGDI EIF4G1 RGS16 GSTO1 IGHG3 IGHV1-18 LTBP4 IL7R PTCH1 UPK3B TRDC COL6A2 AKAP12 RAB11FIP5 IGFBP3 ARFGAP3 B4GALT1 ZFP36L1 BAD KLF13 CDH1 TMOD3 NCOA3 COL1A2 LEF1 TCF7 IRF8 F2R HNRNPK CTR9 CBFB NR5A1 RGS3 BIN1 CLCN5 CREBBP PLXNB2 RGL2 KLRD1 ZAP70 CXCR3 CD48 CD6 FIGNL1 PSTPIP1 CD27 LCK ITGB7 CD72 TNFRSF18 CD3E CD2 VAV1 APOBEC1 COCH CYBB IL1R2 IFIT2 EVI2A SAMHD1 CCL19 GBP7 WARS GDF10 ANGPTL2 DBP CLIC4 ETS1 GNAI2 SPTSSA KLF4 SNRK PSMB10 SGK1 SIPA1 TXNIP RAMP2 BGN GLTP UBL3 GBP3 SOX18 CTGF PDGFRA CST3 NR1D2 RPS10 KLF9 LAPTM4A PISD TAPBP CCNI IMPAD1 CETN2 RHOQ PDCD4 ZMYND11 NDFIP1 SDPR CNBP DDX17 CCT3 PIM3 TEX261 DNAJA1 MYEOV2 CAPZA2 GNS NCF4 EIF4A2 NUDT16L1 SMAD4 IGFBP5 MFHAS1 RRAD SLC25A25 RGS14 CSF1 CYTIP TLR6 HMHA1 NFKBIZ UBE2M CIB1 TMEM205 SEC61A1 ARL6IP5 PGAM1 NRBP1 DAP3 PHLDA3 YIPF3 TIMP2 GNG12 SPIN1 POLR2J FAM60A ADSL NUP107 UBE2G1 SEC11C RPN2 CHTF8 CDK4 CWC22 PRPF8 GNA13 ATP2C1 WBP11 ZMAT3 YTHDF1 ID2 TXNDC16 ITGAV PLCB1 CTDP1 EFNA3 LAT2 TRIM21 SELL DLL1 FCRLA IL27RA TNFAIP8L1 PACSIN1 SPIB SLC23A3 TXK GPRASP1 VPS4B SLC25A28 MX2 KCTD12 CCDC186 ENTPD4 RALB YTHDF3 CHUK PIP4K2C MTPN CD83 RELB PRRC1 N4BP1 RABGAP1L BLNK ALDOA ACTN1 PDXK SERP1 RNH1 CD52 ACTR2 SON MS4A1 DYRK1A ARHGEF3 ST6GAL1 PTPRE PAG1 DNM1 IGHM ACTG2 NR1D1 B4GALNT1 FANCD2OS CXCL12 IL10RB C4A PRKCD GOSR2 SUGT1 ADGRE1 HPS1 RGS19 ITCH IGF1 MDM4 MAP4K4 RECK CXCR4 XBP1 TNFRSF1B TXNDC5 STX7 ARCN1 STXBP3 SPG21 PLRG1 ZMYM4 PIK3C3 SEC16A FAM32A SLC30A5 NNT APOC1 ABHD16A BTBD1 AHNAK BUD31 CIRBP ACKR3 PARM1 RIN2 PTCD2 ZCCHC7 GPCPD1 RBBP6 USP3 SPATS2 HLTF MARCH7 TBL3 KLHL21 MEF2D MAP3K3 CLTB HDAC5 NUDT14 KLC4 SKIV2L ATP6V0A2 EPC1 SLC39A7 CHFR GNL1 OSBPL5 PDGFRB VPS37B GAS6 PCID2 LMBR1L ITPR1 UNC45A PPP2CB SMARCA2 ACOT9 SNX2 KLK1 CELA2A GTF3A USP9X ARID1A FOXP1 UBTF PLXNA3 SLC44A4 EHMT2 TSC2 CCNG2 ATP2A3 H2-OA BLK RAB33B AQR WWP2 PRKDC EMC6 SPICE1 SEMA4A ERCC2 GIMAP1 LMF1 GOLGA5 POU2F1 FUBP1 RCN1 DNAJC15 RRBP1 WSB1 DGUOK RASSF2 ST8SIA4 LTK ARHGEF1 RHOC ARHGEF2 PLCG2 TIMM17A H2-D1 TPGS2 KDELR2 OCIAD1 SLC4A7 USP24 DPF2 ZFX TTC39B PKDCC PCYT2 DIP2B CPD AEBP2 RASGRP2 CXXC1 ELF1 CMTR2 HNRNPDL TNRC6A HTRA2 PDLIM4 ZSCAN26 ZMIZ2 TMEM265 FRYL EIF4G3 TMEM38B H2-EB1 H2-AB1 SPCS2 LY6A C1RA TGTP1 IFI204 SLFN2 MS4A6C SERPINA3N GCDH RNASET2A MS4A4C GPI1 EIF3M SCD1 H2-M3 PRKCB DGKA FCER2A H2-DMB2 IST1 ESYT1 H2-DMB1 RNF10 HNRNPH3 ATAD2B DAG1 SFMBT2 SLC12A4 DCAF12 SPRTN SCN1B PBX2 TSPAN9 COPS7B ITPR2 SLC35B2 APBB3 DPM2 IGHG CTPS2 IGHV1-42 IGKV2-112 SMG5 IGH-VS107 TRAC ZFP703 P2RX1 IGKV6-15 GM15772 ZFP110 IGKV8-24 TRP53BP1 LOC102634459 IGHV1-77 ANKRD2 UPF3B INPP5B IGK-V8 ZFP105 IGLC1 IGHV1-37 GM9840 FAM134B LOC665506 CR1L ZFP706 KLK1B21 IGHV1-62 IGHV5-15 H2-BL IGKV4-59 EPN2 IGKV7-33 IFI202B IGKV4-68 IGHV8-9 MYPOP IGKV6-13 GM40498 CHTOP ERDR1 GM40892 5031439G07RIK EBF1 CELA1 PRPS1L3 VPS53 GM11127 IGKV4-91 1700097N02RIK LOC102641289 NELFA TRIM27 SMIM14 IGKV16-104 ZFP26 SPATA6 H2-M2 CHD7 LOC105247328 CADM1 TMEM222 GM38417 PEX14 PDCD2L IGKV4-57-1 NAT6 ZFP275 RPS4L TRP53-PS IGKV17-121 RORA IGHV10-3 AI607873 IGH-V3609N TCRG-C4 GLTSCR2 ZSWIM1 GM2808 DDX51 PPP3CC POM121 IGHD IGKV4-61 POU6F1 DXO UQCC3 POLM EPB41L4AOS IGK-V28 IGKV15-103 LOC102642602 IGH-V3660 GH LOC102635048 IMMT H2-EA-PS CLK2 ZFP930 GM16340 FTO GM10693 IGKV14-111 D430019H16RIK IGH-V7183 FBXW4 H2-K2 LOC105242484 OLFR71 MKL1 IGKV4-73 2010111I01RIK 5730408K05RIK COPS7A TCRB-J AU021092 AW549877 STRN IGK-V1 ERO1L IGHV1-54 EXT2 CTPS KLC1 IGKV4-74 BMYC IGH-VJ558 ZFP362 TNXB PRKCQ SLC25A53 523 genes upregulated by IAV-infection in mouse spleen We demonstrated the molecular mechanism of the antiviral effect of orally administered cystine and theanine (CT) and further explored how CT acts on the dysregulated cytokine and immune response characteristic of COVID-19. UBL5 AP2A2 BCL2L1 UHRF1 RB1 CAPN5 TRMT1 GHITM KPNA2 TBK1 MACF1 EPB41 CCND3 IFITM3 PKM NBR1 ELAVL1 EPS15 UBA1 SIRPA POLA1 NFATC2IP FBL PHB2 COPB2 TUBA1C PABPC4 RAD23A TUBA4A NUTF2 STAT1 TRIM25 B2M NDUFB9 CLCA1 RCC1 STOM NUP85 ISG15 HSPA8 EVL SCARB1 USP7 CHMP2A CASP3 MX1 RCOR1 MAPK1 FBXO9 ATXN2 TOMM70A PSMB1 TM7SF3 KLF1 FAHD1 NDUFB6 ZFP106 RPS17 ASS1 NINJ1 RBPMS GADD45A CKS2 SLPI COX7C ISG20 TPST1 MAP7 TOMM40 C1QC RMDN3 USF1 LGALS3BP PRKCSH INPPL1 TOR3A PGD C1QA GRINA FKBP8 DNAJB2 LMNA CCT5 TOP2A PNP LMO2 TK1 EZH2 LMNB1 CCNB2 HSD17B4 NEK2 CLCN4 DDIT4 MCM2 RRM2 CDK1 CDC6 BIRC5 C1QB PRDX1 HEBP1 KIF11 CCR2 CCNB1 CDC20 IGHG3 IGHV1-18 PSMB2 HP MKI67 TPI1 TYMS ZFPM1 AZIN1 HINT1 DDX19A ABCF1 STAT5A MINPP1 PSMD6 FOXL1 TCF7 DCK MAFK PRC1 PLXNB2 OGFR SMC2 CD48 RSAD2 E2F8 IRF7 FIGNL1 KIF22 TAP1 NUSAP1 MCM5 IFIT1 H2AFX CCNF LAG3 RAD51AP1 IFIT3 SFT2D1 CDT1 CD86 COCH CYBB CD5L USP18 IFIT2 ALAS2 SLC4A1 SNCA PLAC8 IFIH1 PML ADAR GBP2 GCH1 DAXX IFI35 TRAFD1 SAMHD1 UBE2L6 UBA7 GBP7 WARS FTH1 CLIC4 CYTH3 TUBA1B YBX3 CHMP4B GSTM5 RHOG CAPZB ATP5J IRF9 GBP3 CTGF RPS19 EIF3E H2AFZ MAT2A ALDH1A1 RPS10 PFDN6 LAPTM4A TAPBP NDUFB3 FHL1 RGCC LYPLA2 TEX261 AQP1 RNPS1 PIGQ EIF4A2 SRSF3 BEX4 ATP5C1 SERINC3 MIEN1 BNIP3L DEK ANK1 SLC25A25 ZNFX1 NDUFS2 PDLIM1 HMGB3 UBE2M MCRS1 RRM1 PSMD1 ATP6V1C1 M6PR TMEM208 AIFM1 RNASEH2A PTTG1 PARK7 LAMTOR5 DAP3 AHCY PLGRKT LSM7 PCNA POLE3 RFC4 TMPO ADSL CERS2 ETF1 RPN2 SF3B5 ETFB CDK4 CWC22 PRPF8 ATP2C1 FAM117A MKRN1 ARL6IP1 CKAP5 YTHDF1 SRSF2 MNS1 HDGF CPNE1 ANKRD13A ATP5E PLCB1 EFNA3 SNHG5 FEN1 ASNS TRIM21 MARCH5 CTSE TSPAN33 FES SLC23A3 TFRC NFE2 CDKN2C MCM4 SLC20A1 MCM7 LIG1 LGALS9 MRPS11 SP100 MX2 GALNT11 RALB CHUK PIP4K2C FBXW11 ARPC1B N4BP1 BPGM GNB2L1 ACTN1 MSRB1 COX5B XPO1 GZMB ADAM10 IGHM FANCD2OS TAL1 GFI1B PRDX2 SEMA4D GLRX3 GOSR2 PSMD9 PSMG2 VPS29 SURF4 ACP1 ARF5 KIT CXCR4 RNF11 HARS PSMD5 XPNPEP1 HMBS FCF1 PSMC3 PIK3C3 FAM32A RFK COX6B2 ALAD APOC1 ABHD16A AURKAIP1 BUD31 CDK5RAP3 CNPY2 NDE1 ST3GAL5 RIN2 PTCD2 SETD8 GPCPD1 USP3 HLTF SLC38A5 TSR1 UROD SLC25A44 SIVA1 GUCD1 PBRM1 GALNT4 GSPT1 SNX2 ADD1 ARID1A SSRP1 IIGP1 ZCCHC6 RHD EMC6 SPICE1 LY6C1 GTPBP1 ABCB4 GCLM CDK8 DNAJC15 MT2 EPOR PDAP1 RBM38 SART3 ANAPC1 NUP50 SUDS3 RCC2 IFRD2 MRPS34 TCOF1 UBP1 TXNRD2 COX7B MGST3 TIMM17A CYB5R4 IFI27L2A GAS5 FAM213A SLBP MRPL30 USP24 DPF2 DDX24 RBM14 NDUFB8 SSX2IP LY6D AEBP2 LRRC8C ELF1 TNRC6A IDH3G ZMIZ2 NOCT ATPIF1 RPAP1 OTUD4 HNRNPA3 IDNK FRYL PPOX EIF4G3 AK6 STYX TMEM38B IGTP EIF6 IRGM2 TUBB5 SLFN4 LY6A TRIM30A TGTP1 IFI47 IFI204 IRGM1 SLFN2 SERPINA3G FCGR1 MS4A4C HBA-A1 H2-T24 EIF3M CD24A FTL1 WDR26 RNF10 DCAF12 SPRTN RELL1 NTPCR BROX ITPR2 MRPL39 APBB3 FAM220A RHAG XPO7 UROS GYPA PCYT1A SPECC1 SMAP1 CAR1 IGHG GM4246 CES2G PTDSS2 CAR2 GM10177 UBAC1 ISCA1 FAM46C PLA2G12A GM11336 KIF4 CD59A GM9706 SPPL2B HEMGN EPB42 LOC102641872 HELB NUDT4 IGKV2-112 TRAC GM15772 IGKV8-24 LOC102634459 IGHV1-77 INPP5B GM9840 IGHV1-62 IGKV4-59 IGKV7-33 IFI202B MYPOP GM11127 TRIM27 GM38417 PEX14 RPS4L IGKV17-121 IGH-V3609N IGHD LOC102642602 IGH-V3660 GM16340 GM10693 H2-K2 TCRB-J ERO1L IGHV1-54 IGH-VJ558 1110001J03RIK CASK 2810428I15RIK D17H6S56E-5 QRICH1 EIF3J1 FDX1L 1110008F13RIK D17WSU92E OLFR29-PS1 0610007P14RIK SRPR ANK GM10362 GM5446 A430005L14RIK LOC102641325 D13ERTD608E LOC102642752 SLFN3 E4F1 SLMO2 CHCHD7 TUBA3B 2700029M09RIK LOC102641294 MEMO1 EMC8 ZFP131 455 genes downregulated by IAV-infection in mouse spleen We demonstrated the molecular mechanism of the antiviral effect of orally administered cystine and theanine (CT) and further explored how CT acts on the dysregulated cytokine and immune response characteristic of COVID-19. CD79B UIMC1 PIGS COL6A1 SEC14L1 MDN1 PTEN SQSTM1 CSDE1 CAPN2 PPP2R1A ITGB1 DDX5 THY1 HIST1H1C VPREB3 ATP6V1A RHOA GOLGA7 PDZD11 YIF1A PFKL PKM ZCRB1 NDRG1 FURIN F5 TUBA1A UBQLN1 COL4A2 IFITM2 TMEM176A CSNK2A2 MFGE8 BAG6 MAT2B CD4 IL17RA MAP3K1 SLC44A2 RAB5C PHF7 ITFG1 FAH VAMP8 TLN1 CD55 ADK CAV1 ISLR MIF4GD MYO10 HIST1H2AL HES1 HIST1H2BC RPL41 CFH SLC25A4 ATOX1 RPL19 ABCA1 RPLP1 LSP1 GSK3A HS1BP3 GSN SNRPB CD37 GNB2 LRP10 MYADM PIGK CD81 EIF3B CMTM6 MRC1 IGKC PLBD1 CEBPA TK2 IGHG1 LDLR MAPK6 CTNND1 CAPNS1 SMAD1 C2 IGHG3 GSTM1 IGFBP3 CAMP TRAM1 COL1A1 GADD45B ELANE CYCS LTF GIPC1 CXCL13 CLU INPP5D NR2F2 GABARAPL1 IRF4 HIF1A PSMA3 RERE TBL1X PTPN22 CD3G CYFIP2 CD5 PTPRCAP ARHGDIB RAC2 CORO1A CD2 COTL1 CD19 RNASE4 BASP1 CCL19 GNAI2 ZFP36 LASP1 SEPT4 CNN2 MYL12B RAC1 EEF2 SIPA1 MYL12A NFKBIA ID3 GSTP1 BGN JUNB U2AF2 RBMS1 WBP5 GNG10 BCAP31 CST3 PLIN2 DCN GPAM BTG1 LIMCH1 NACA CTSH ARPC2 NME2 VDAC2 DNAJC8 TMEM176B SLC12A2 MORF4L1 CCNI IMPAD1 KDELR1 RHOQ CD74 PCNP SDPR NDUFB7 FDX1 PEX6 KRTCAP2 ATF4 ROMO1 PQBP1 ARF1 LAPTM5 CDIPT DSTN STK38 GM2A SAT1 MARCKSL1 NXF1 FSCN1 IGFBP5 OAT SSR3 CD9 S100A13 POU2F2 GPR182 NAPSA MOB1A SGCE LAMTOR2 GYS1 PGAM1 CKB AP1S1 AMZ2 TMEM126A SEH1L PPP1R18 ATP5L FAM107B ARMCX2 PPP3CA STAG2 NEK7 WBP11 USP10 RUVBL2 FKBP4 RANGAP1 SRSF2 TBL1XR1 ARFIP2 CREBRF TMEM115 IFT46 IFT88 VAMP5 TRA2B LAT2 FAM105A CSK ATF6B CCR6 WAS SPIB PTMS MADCAM1 PDPK1 MLF2 PRKACB THRAP3 CD83 RELB GLUD1 PROCR PXK BLNK ALDOA CTSA EIF4A1 COPE ARPC4 GPSM3 MPO S1PR1 CALM2 CRLF3 PRKAR1A SRSF5 JARID2 SLC30A3 IGHM ENPP2 B4GALNT1 IFNGR1 PGK1 PRKCD GLRX3 PSMD7 UBA2 UBE2H ITCH IGF1 HHEX GNAS SYK PAX5 RAB4B TXNDC5 ERP29 PLEKHB2 TXN2 USP5 SEC22B TBRG1 COPA FKBP3 ARAF PSMC5 MAPKAPK2 STK10 GALNT1 ASAH1 AKIRIN2 CMTM7 CHKB ACAA2 MID1IP1 PARM1 STT3B SPNS1 ENG NCOR2 POLR2A ARFGAP2 GMFG TPP1 RTN3 PPDPF SMAP2 ARHGEF7 AGAP3 PEX5 PURA AGFG1 CPNE3 USF2 ELN KLK1 SOD3 CELA2A ASXL1 DNMT3A BMI1 RAB7 RBPJ ATP2A3 H2-OA PRR5 TRP53INP2 SERPINA1A BLK TFPI CD79A GALK2 WDR48 SLCO3A1 LMO4 NFYA SGPP1 PPIF HP1BP3 LAPTM4B NFKBIB ENO3 CS SERPINA1B H2-D1 SERPINA1C DBNDD2 PTRF IMP3 KDELR2 MAX SETDB1 DNAJB6 VPS26B ANXA6 UBA5 MTSS1L GTF3C1 A4GALT SLC50A1 DHRS3 ANKRD10 NOCT PIP4K2A ZSCAN21 BRAP TUG1 TMED7 MPRIP SAA3 MS4A6C ACADL LAMTOR4 BPHL GRCC10 ISOC1 CYP4V3 GPI1 PNRC2 SCD1 PRKCB CCL21A NGP SIN3A ZC3H3 VAPB MED27 TSFM ITPR2 DPM2 GM29779 GM37013 IGHG VAMP4 STX5A PPP6C TIMM22 0610010K14RIK TCEB3 MRPS24 IGKV10-95 ANKRD46 PPP2R4 GM5879 TRAC GM9840 FAM134B ZFP706 KLK1B21 5031439G07RIK CELA1 SMIM14 IGKV16-104 CADM1 IGK-V28 IGKV15-103 IGH-V7183 KLC1 LOC102643180 IGKV10-96 ZDHHC16 GAR1 ZFP385A 2700094K13RIK 1700094D03RIK MRPL45 TEC KLK1B5 LOC105244208 MIR142 H2-DMA CD8B1 GM42035 UBE4B IGKV1-88 IGLV3 CLEC16A SYPL BCL2A1A CRCP PPP1R21 STK11IP TSC22D4 IGK-V21 SCD2 MBTD1 CLK2-SCAMP3 KLK1B1 ZNRF2 ZFP277 FAM195B DTX1 LOC105242499 LOC102642637 BC094435 GM8893 PSPH GM3511 GGTA1 SDHAF1 464 genes up-regulated by SARS-CoV-2 infection in Vero E6 cells from GSE153940 SARS-CoV-2 infection of Vero E6 cells Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/OFCkPa3Su ADAMTS1 PTPN14 XPO6 ABCC1 LARP1 CISD3 BCAR1 RRP9 ASAP2 EP300 GOLGA3 KLF6 NFKB1 CEP68 BRD2 FRMD6 GIGYF2 MARK3 FAU AAR2 PI4KB NSD2 ISG15 SRC MARK2 SLC7A6OS TIMM44 YARS2 NCOA5 RPLP2 AUTS2 RPL27 SH3RF1 GATAD2B SNORD17 GADD45A GPRC5A RPS14 SRRT RMDN3 ADCY7 USF1 MBD6 IL4R ZNF316 MICAL1 SLC3A2 ARHGEF10L ATG4B AKAP1 CIC SMAD7 XXYLT1 RAB20 ADAM15 LDLR DDIT4 STARD13 SPRY2 SLCO4A1 DUSP7 TBL2 SNX8 ZNF574 MIB2 SEMA4C U1 NUAK1 IWS1 B4GALT2 PHOSPHO1 MYC TUFT1 NOTCH1 KLF10 TGFBR2 GADD45B TRAK1 PLAUR RDH13 SEMA4B IFFO2 ARHGEF5 KRT80 DNAJA3 BCL9 PRICKLE2 AXIN1 ATF3 MAP2K3 STK40 BCL3 PHF12 KMT2B RERE CREBBP TNFRSF1A KDM4B ZNF385A NUAK2 PHC2 SBNO2 TAP1 LRP8 PML SOCS3 PIM1 INHBA SLC25A22 EHD4 ZFP36 LRFN4 IER3 IRF1 DUSP1 NFKBIA IRF9 JUN S100A4 PISD ATF4 PIM3 KDM6B PPP1R15A THNSL2 TNFAIP3 ZNF205 NAT8L AMOTL2 BRD1 PPP1R15B NEURL3 LIF IRS2 IER5 NGF YOD1 ZNF367 BHLHE40 MAFF NFKBIZ TSC22D2 SERTAD2 CDC42EP3 PFKFB3 KANSL1 FOXO3 IL11 MSL2 C12ORF10 PPP1R18 GNA13 TTC7B RHPN2 FXR2 KLF7 YTHDF1 NOP14 ID1 TSPYL4 SURF2 PURB NOA1 MAML1 SFSWAP MUL1 ABL2 GRAMD4 ZC3HAV1 CEP131 ANKRD13B XRCC1 CPNE2 IFI6 FNBP4 SNORA21 RNF166 UBN1 LPCAT1 TPRA1 PLK2 PMAIP1 ARL5B RHBDF2 OPTN TRIM26 AMPD2 PDLIM2 SESN2 TRIB1 LMCD1 SEMA7A REXO1 STX5 CAMSAP1 RGS19 PIK3CD AGO2 SPEN XBP1 NFKB2 TGFBRAP1 CARS2 HAUS8 ELL AIP DDX56 ZNRD1 TRIM11 TRAF2 SMIM12 ATP23 ATP6V1H CITED2 MID1IP1 URGCP ANKRD11 EHMT1 FLCN HIRA EPHA2 RASSF1 ZBTB10 SOCS6 HMGXB3 KLHL21 MEF2D ATXN1 DUS3L PPP1R3B VPS18 CHST3 PODXL AKAP13 SIRT7 RHOBTB2 KATNB1 SNORA48 E2F4 NOP56 RRP12 RAPGEF1 SERTAD3 SLC38A5 DAPK3 AMOTL1 PLEKHM2 UCK2 TXNDC11 PPP1R12A WDR74 ATP8B2 TRIM4 NFKBIL1 TNIP2 TAB1 TRIP10 ZFHX3 RNF216 PC ZBED4 SRF TGFA LMTK2 RREB1 ARID1A MRTFA PIAS4 ZBTB18 DAB2IP CHD6 TSPAN15 ASXL1 BACE2 DDX27 ARHGAP6 TNFRSF10B AMBRA1 SLC30A1 PPM1D RAB24 BCL2L13 LMF1 MTA1 TRIM35 ANKLE2 SNORA80C LAMA4 TRAF4 CCN1 KMT5A ILKAP SART3 NUP50 REXO4 BYSL POC1A RRS1 IPO4 WDR4 ING1 ZNF282 ZNF746 GRK6 PLCG1 MAP2K7 IMP3 GTF3C4 SCAF4 TBC1D22B RBM33 GGA3 ARHGAP17 IP6K1 MTMR3 EPS15L1 AEN KDM2A ABTB2 FEM1A GPATCH2L TADA2B ARHGEF28 L1CAM GSE1 TMEM201 ISG20L2 INTS5 NOC4L DIDO1 RBM15 KAT6A CREBZF RAD54L2 PDZD8 CDK13 CLIP1 PPP4R3A DNAJC4 GRAMD1A UCKL1 PDLIM4 TRIO ZNF609 ZMIZ2 HPS6 TEAD4 FARSA SETD1A ZNF598 UBE2O MORC2 ZBTB7A CAPN15 IRGQ SNORA47 ARID4B SCARNA6 TGIF2 SNORA57 KMT2D GTF2H4 SNTB1 TTC28 PID1 DGKD SH3BP5 PRR14 THAP3 U3 SNORD15 C1ORF35 ARHGEF17 ANKS1A DDX49 ADPRHL2 MED27 ZXDC ZMYND8 FAM193A RUFY1 B3GALT6 PHF1 ACSF3 SPECC1 NELFA TMEM222 CLEC16A MAU2 SNORA10B SNORA16A ARFGAP1 N EEF1AKMT4 SNORD94 SCARNA20 MARCHF9 AFF1 SNORA46 SNORA64 ITPRID2 TFAP4 S RTL6 SNORA52 PHF2 ASB6 SNORA38B NUC SRP GP05 KAT8 SH3BP5L MED17 FAM53C RILPL1 ZNF394 CARS1 RNF217 WDR33 TOP3A ZNF496 SNORA62 TLNRD1 MTSS2 SNORA17A PSMG3 WIZ SNORA74 SNORA80B POLR1E PANK2 SCARNA22 SNORA5B PGS1 RIN1 ORF7A SNORA71 SUGP1 ABT1 NOB1 ORF1AB ARID3A SNORA37 KLHL26 TACO1 UNK SPPL3 DIPK1B ORF3A 447 genes down-regulated by SARS-CoV-2 infection in Vero E6 cells from GSE153940 SARS-CoV-2 infection of Vero E6 cells Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/OFCkPa3Su CASP6 TIMM8B IFNAR1 ERMP1 FKBP1A PIGS PBLD ATP6AP1 CTSL GHITM VCP NPTN ETFA PRKACA NEK9 CDH17 HNF4G ACADM NPC2 RBL2 DPY19L1 PPT1 CYB5B AP3B1 NDRG1 SRP54 MPZL1 RAB18 AGPS GGCX ERP44 POGLUT2 EPB41L3 CLCC1 APOBEC3G MSN STOM MAT2B PLS3 CAT GOLGB1 PPIA TOP2B G3BP2 NFS1 ITFG1 MDH1 GLO1 RBKS CLDN10 ADH5 COX15 TMEM30A PAIP1 UNC119B TRIM37 ACO1 RNF167 PSMC3IP DHRS1 RNF128 OCIAD2 NDUFA10 SH3D19 TSPAN6 NDUFB2 CNN3 DSG2 EPCAM SCIN CYBRD1 DYNLRB2 ACOT13 ATP1A1 SEL1L PDIA6 STMN1 DDOST PGD SEC24C GANAB UNC50 TMED9 CMTM6 SLC6A6 DDB1 NCSTN NDUFB5 SCARB2 CTSB FKBP9 SCPEP1 POMP RBBP8 ALCAM ANXA5 MRPL15 AURKA DLGAP5 LTA4H KIF11 HEXB IDH1 MICU1 PRDX3 PAPSS1 SPATS2L TPI1 AKR1C3 CTNNA1 MMP1 APLP2 TGFBR1 B4GALT4 NRDC TMOD3 MCCC2 WLS RAB4A PSMA3 RBM47 SMARCA1 ECT2 CKAP2 HMGB2 LGMN CLDN2 EPHX1 PIPOX SLC3A1 TSC22D1 CAV2 TFG PSENEN PSME2 GNAI2 SPTSSA AKR1A1 CRYAB COX17 SPARC SYF2 ARL2BP GSTP1 MORF4L2 ITM2B NPNT GNG10 BCAP31 CST3 EFEMP1 BTG1 LYZ SNRPD2 LAMP2 PSMB6 COX8A PFDN6 GLUL CETN2 PLXDC2 TP53INP1 PDCD4 NDFIP1 NDUFA5 NDUFA2 SLC39A1 PSAP CAPZA2 RBM3 TMED10 GNS GNG11 VPS26A ARL1 CETN3 NUCKS1 ANAPC5 OAT ACADSB SERINC3 PGRMC1 TMED2 MIEN1 BNIP3L SPOCK3 SERPINI1 S100A3 PLA2R1 TSPAN31 NDUFS2 ATRAID DPM3 UBE2A MAGT1 PRR13 HAT1 MMP10 MRPL46 VAMP3 LAMTOR2 WBP2 RRM1 ATP6V1C1 MSRB2 CHMP5 TMEM205 PJA2 NDUFAB1 ARL6IP5 MIF AIFM1 EPDR1 IDH3B SARNP YPEL5 DDX18 MRPL13 AHCY MAGOH MRPL42 DNER ANP32E RCN2 TIMP2 MSH2 WDR54 UCHL5 NDUFA8 ZDHHC6 SYPL1 PCMT1 FAM107B NIT2 PDCD10 LACTB2 VAMP7 SPCS1 HMGN3 GTF3C6 GMNN LAMB1 SCG5 C18ORF32 UBA3 CBX1 USO1 NDUFA9 FOLR1 HSD17B11 TXNDC12 MFAP1 XPR1 TOB1 MKRN1 GLB1 APOBEC3C IK MSMO1 ZNF385B HABP2 YIPF6 ZMPSTE24 CDH6 CD46 MCM6 RPA3 TRIAP1 SLIRP PIGW PIGT SFXN3 PSIP1 BBS2 ASRGL1 RFC2 PDZK1 PRPS2 BET1 STARD4 GLG1 GALNT11 CLUAP1 CCDC47 RALBP1 ATP10D CTSA COX5B RAB29 CD44 ADAMTS9 TWF1 VPS29 PEX2 PPA2 RNF5 NCF2 CA12 ARCN1 GBA SELENOF STXBP3 UGP2 SNX6 COPA HTATIP2 SAE1 GDE1 COX16 FMC1 CALCOCO2 SPP1 YIPF5 SYAP1 YIPF4 PPM1A ALDH3A2 ATP1B3 ASAH1 CMPK1 COPS6 CIRBP ACAT1 ATP5PF ACAA2 C11ORF58 BCCIP SMIM3 PTER STT3B TMEM123 THEM4 HLTF CWC15 THOC7 MSI2 TPP1 PMM2 GLT8D1 CPNE3 ROBO2 FAM3C CISD2 FBXO32 CYB561A3 MRPS22 IVD DAP ADIPOR2 MRPL40 PRKDC TMEM106B IL13RA1 SPTLC3 GCSH ICMT PHF6 MRS2 MCM3 PPP2R5D CCDC88A RRM2B PSMA5 LAPTM4B TMEM59 SELENOT SFXN1 HIBADH AHCYL1 BCKDHB NUDT21 SLC39A6 F11R DUT IARS2 OAZ2 GPC4 MFSD1 RHOBTB1 LPIN2 FAM168B DPCD EIF2B1 TSPAN12 TMX4 RPA1 B4GALNT2 NDUFB8 PXMP4 LANCL1 DCUN1D1 PGRMC2 CD109 CLDND1 RPL39L PHYH HSDL2 MICOS13 BEX3 H2AZ2 NIPAL3 ATP11A RBBP9 ERGIC2 PYURF BLOC1S5 PLPP5 SLIT2 VMA21 PAIP2B PCCB ECI2 NTPCR EFCAB14 PIGN DENR BDH2 STRAP SNAP23 COMMD7 CMC4 SMIM14 RDH10 DYNC1I2 STRADB JADE3 GABRA2 ZFAND6 JPT2 WASHC3 TRARG1 DARS1 GNG4 SLC36A4 KIDINS220 CASC4 TCTN2 EAPP PLAAT3 SRBD1 LIX1L CCDC25 TMEM35B TMEM106C SLC39A9 TMEM185A EXOC5 500 genes up-regulated by SARS-CoV-2 in human cardiomyocytes from GSE150392 SARS-CoV-2 infection of human cardiomyocytes Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/Eju1fcXzF F2RL1 PTPN14 IL1B RSRC2 BIRC3 IL6 GDF15 CD14 CCL2 MVP MALL SQSTM1 LOX THY1 IL1A ANKS4B NPC1L1 MYRFL NDRG1 NEDD9 RUNX1 ETV4 CD200R1 TLE3 BRD2 SERPINE1 SNIP1 OAS1 PTX3 PLOD2 TLE1 AGTR1 SLC30A7 PCK1 PLAT ITGA4 CXCL2 STOM IFNB1 FERMT3 STC2 MX1 MYD88 CHD1 MYO10 CXCL1 ITGA2 KLF5 INSYN2B TM4SF1 BMPR1B HES1 IL33 NT5E HLF NR4A2 SH3RF1 ELF3 OSMR CCDC80 SERPINB2 FNIP2 ANKRD33B SIX4 ISG20 TPST1 ATP10A ADCY7 PARP10 TRPV2 TGFBI DOK2 SLC16A3 ADGRE5 ITGA5 HLA-E MRC1 LMO2 C3AR1 IFI44 STARD13 CARD6 CDKN2B SLC43A3 CXCL8 ARL4C PTGS2 SLC1A7 CRY1 NUAK1 LINS1 SLC2A9 MYC KLF10 SLC2A3 SLC2A5 TRAM2 GADD45B PLAUR SPINT1 OSM JMJD6 GPR87 GTF2IRD1 RARG FAM83G SLC7A5 HR SOX17 FGF7 DKK1 FOXL1 ATF3 IRF8 TPBG BCL3 HELZ2 NUAK2 SBNO2 OAS3 IRF7 GNG2 SELPLG TAP1 GPR176 SELE IFIT3 OAS2 CXCL3 APOL6 CMPK2 CDH16 PTAFR SUCNR1 MLKL SOCS3 ARSI PTGES PIM1 CASP4 FAP INHBA FOSL1 HAS2 SAMHD1 HAS1 GFPT2 ARNTL ANGPTL4 DBP THBD KLF4 TOX2 FOS BMP6 IRF1 SGK1 DUSP1 ICAM1 DTX3L NFKBIA JUNB RAPGEF2 GBP3 JUN DRAM1 KLF9 IFI44L ARRDC3 PIM3 CCNL1 PHLDA1 GEM ADAM32 ZC3H12A DDIT3 LTA SLC25A25 AOC3 TRAF1 EGR2 NR4A3 RGS4 HSPA6 ART4 PPP1R15A MYCT1 CSF1 TRIM22 KCNE4 PTGER2 TNFSF4 TNFAIP3 SPDYA CIART PLA2G4C TG STC1 TOR4A DUSP6 LIF IER5 CSRNP1 BHLHE40 MAFF NFKBIZ KANSL1 IL11 FOSB SH2B3 SPRED3 LMAN1 AMIGO2 RB1CC1 RLF USPL1 INTS6 GPBP1 PTBP3 TAF4B GRB7 HOXA5 ARRDC2 CREBRF IP6K3 HIVEP2 KDSR VEGFC CDH6 CENPL TMEM200A IL1R1 ZBTB2 REL ABL2 SUSD3 ANXA10 IL15RA SMOX TRIM14 PDK4 MAP3K8 IRAK2 MEDAG PRKD2 CYP1B1 CASS4 PCSK9 PER1 SLC20A1 GALNT12 NHS TFPI2 SP100 GORAB CKAP4 PAPSS2 LINC01209 EMP1 PPP1R10 LIMA1 CD83 RELB MICB BAZ1A PMAIP1 DUSP4 SLC2A10 SP140L ACHE BTN3A1 CHSY1 TRIM38 CA9 SRGN AMPD2 CSF2RB CD44 PDE7A NBPF10 MRGPRX2 HRH1 FJX1 BCAR3 CLK1 SERPINB8 CHKA PIGA KCNN1 PAPPA NR4A1 TMEM255B LOXL2 IL1RL1 DOK5 CRLF1 SPOCD1 NR1D1 GAL3ST1 SPRY4 NCF1 CD68 NCOA7 C1QTNF1 C7ORF61 NPTX2 CDC14A HS3ST3B1 PRKCD CCL7 TMED7-TICAM2 AGO2 SPEN HFE TNFRSF1B CA12 NFATC2 NFKB2 TXNDC5 PDCD1LG2 UVRAG BHLHE41 TGM3 SLC12A8 FLCN EPHA2 RBBP6 SMIM3 PTP4A1 KCNJ6 SNAPC1 PLA2G4A CDCP1 GREM1 SGK2 HAPLN3 PLK3 ENG TET3 MFSD12 BCL6 KCNH7 NFKBID RNMT SNAI1 SPRED1 SPHK1 APLN SRPX2 SLC5A3 ACVR1C PYY CPM CPA4 PER2 OVGP1 SLC22A3 ZPLD1 PCDH15 JMJD1C SSTR1 ASXL1 ZBTB21 CHD2 TMEM119 KCNAB1 EVA1A PRR5L CRTC2 FPR3 TFPI SLC19A2 CXCR1 PPM1D ULBP2 CTH PTBP1 ZBTB17 BAAT C9 RFX3 TNC GPAT3 UGCG PVT1 SHMT2 ERO1A LOXL3 UBASH3B TMEM87B PFKFB4 AEN ELMSAN1 PDZD2 ZSWIM4 SKIL ARHGEF28 L1CAM CLK4 HIVEP1 NBPF14 FAM43A IFRD1 CLMP CACTIN SERTAD4 PDE10A BICC1 AGAP6 RAB27B PCF11 FOXN2 AC002480.2 LRP5L H2BC8 H2BC18 ARID4B GRIP2 ATL3 AC107959.1 EMILIN1 SNX16 ZNF143 PPP4R2 GOLGA7B LAYN GALNT15 ADARB1 DAB2 SSUH2 PDP2 NR6A1 CARS1 AC090023.1 KCNG1 TMEM72-AS1 TTLL8 RFLNA AC025263.2 GPR180 Z84488.2 AL137129.1 CNTD2 AL358777.3 FNDC11 NXPE2 AC073610.2 AF001550.1 SMIM41 AC092687.3 SNHG26 OOSP3 AC005532.1 AP003108.1 AC074091.2 WNK4 BNIP5 NPIPB7 CSPP1 DCBLD1 PTGIS TMEM158 ACTBL2 POFUT2 AC015813.2 AC116366.2 AC004083.1 LINC01119 AC133644.3 AL049844.1 AL137026.3 LSMEM1 AP003396.5 PXT1 AC011603.3 AC000072.1 KRTAP5-2 TIGD3 SLC35E1 AC117488.1 LDB2 INA LINC01823 NPIPB6 TNFAIP8L3 NRG3 CABP5 AC008770.4 UBE2Q1-AS1 ASPHD2 IPMK CFAP43 AP000790.1 OSTN-AS1 CFAP45 PTPRN NPIPB9 AL135905.2 NBPF19 TGIF2-RAB5IF 500 genes down-regulated by SARS-CoV-2 in human cardiomyocytes from GSE150392 SARS-CoV-2 infection of human cardiomyocytes Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/Eju1fcXzF GOT1 TRIM55 SH3BGR TMEM97 AGTR2 CENPF VIPR1 BZW2 C11ORF74 PRKAR2B SLC5A12 EPHX2 CAT FRMD3 ACADS PDE4DIP UBE2E1 SCRN3 ADHFE1 NSMCE4A ATPAF1 ALDH6A1 TMEM71 PPP1R14C NEBL STK33 UPK1B HOPX METTL7B NME5 CRYM PBX1 ITGA10 KLHDC9 SORBS2 KIAA1143 CHCHD10 EMC10 PLCB2 GPD1 CPVL PLK1 MYBL2 TOP2A ZWINT CDCA8 CCNA2 TK1 TROAP CCNB2 SMARCD3 GTSE1 CDKN3 NREP AURKB NEK2 SHCBP1 NUF2 CDCA5 ITGA7 KIF2C KNSTRN NUDT16 DLGAP5 RRM2 CDK1 CDC6 E2F1 BIRC5 KIFC1 ROGDI LGALS3 CCNB1 NCAPH CEP55 CDCA3 CDC20 HJURP TRIP13 CENPU CDC45 KIF20A DTL NCAPG TYMS CORO6 ENPP5 MTERF2 MLF1 G0S2 YPEL1 AC008440.1 NAP1L2 BMP7 PLCXD3 SLC2A8 AQP10 FOXM1 NECTIN1 EPN3 CDH3 FGF10 SFRP2 FGF12 ODAM TYRP1 PRC1 UBE2T ASF1B KIF22 GINS2 CKAP2L CHAF1B GATM FAM83D SPC24 OIP5 NUSAP1 CKAP2 MCM5 PBK SPC25 CENPM DEPDC1 FAM78A STAT4 HMGB2 NDC80 NEIL3 RAD51AP1 TNNT2 CASQ2 TRDN XIRP2 HSPB3 TNNI3 FABP3 ITGB1BP2 CSRP3 TXLNB NPPA PGAM2 MB CKMT2 MYL4 MYL7 POLE2 ALAS2 DHFR TMEM143 CPNE5 HAND2 TNNI1 KCNIP4 ACTC1 COX6A2 TNNC1 MYL2 CLIC5 QDPR HADH ACTA1 LIMS2 GYG1 CD36 NUCKS1 FXYD1 MYZAP LDB3 FBXL22 SULT1E1 BMP5 EDNRA COL21A1 ASB2 C1ORF105 COL9A1 GPX3 NDUFS2 HMGB3 ATP6V0E2 FGF13 AKR1B1 DECR1 SRPK3 SORCS3 ZNF385B ZBED8 IFT88 HFM1 FEN1 APOBEC2 TSPAN32 GPR183 ADPRHL1 RXRG C14ORF180 TCAP CRACR2B FAM185A TESC PLAC1 PTGR2 CLGN CRABP2 DRD1 FAM111B DIRAS3 RHNO1 REC114 UGT2B28 NICN1 GALM MYL9 RASSF4 PDK1 DOK7 DAPK2 LSMEM2 MLIP SLC30A3 SLC38A3 HRC CASQ1 HAND1 GJD2 CPNE4 CLCNKB CORIN KCNH2 CCDC34 MOG MASP1 GATB PEX3 RMDN1 PARP1 TRIM54 HAUS8 EEF1A2 ANKRD18A ACOT2 ACOT1 ATP5F1A CIRBP ACAT1 C11ORF71 ALDOC FILIP1 ANKEF1 SUSD2 PDE1A PRIMA1 SFRP5 NES FXYD6 ATP6V1G2 KCNIP2 SIRT3 HCN4 FAM13C CALN1 COL11A2 FERMT1 TMEM144 PCLAF RAB9B SCHIP1 FSD2 HRH2 CAMK2A RPE65 CPT2 ACSM5 SLC27A6 MAP3K20 GUCY1A1 SGO1 PRMT6 CAV3 RBM38 BABAM2 TMSB15A SETMAR MMP15 HSPB7 RCSD1 SELENOP TMOD1 ENO3 DTNA PDHA1 FMO4 HNMT BCKDHB RMI2 SH3RF2 AIF1L CSPG5 MMAB TMEM141 MAOB PGAP3 FPGT VSNL1 EFCAB7 CCDC121 PPP1R3C MAN1C1 FRMD5 MANEA NHLRC3 ICA1 PDK2 FOXRED1 TSEN2 KLHL23 A4GALT DMAC1 SLC26A9 PHYH TLCD4 AC008966.1 NIFK-AS1 FANCL LRRCC1 AC022034.1 OXCT1 LDHD NUDT7 ISOC1 AMT STRIP2 CAP2 CAMK2B REXO5 SGCA TRH SPEG DES MTURN CLYBL SORBS1 TAF9B ALDH5A1 C1QL1 INAFM2 C15ORF41 TMEM106C AC091551.1 LINC01182 ATP1A2 FAM47E SLC25A21-AS1 NAP1L3 MTUS2 AC012060.1 LINC00667 LINC01278 DUBR LINC01880 INKA2-AS1 AL392089.1 AC097526.1 MSS51 FGF13-AS1 MIR133A1HG ZNF418 AL008729.2 PPP2R3B PPP1R1C RTCA-AS1 SMCO1 SMPX AL356123.2 EFNB3 TBX5 AP002761.3 AL158829.1 STARD4-AS1 ULK4 AC074387.1 FITM1 TECRL AC092171.5 AC147651.1 LINC00648 MARCH11-AS1 MYOCD AP002360.2 GPR22 LINC01621 COQ7 AC006333.1 AC109583.4 NAV2-AS2 DGLUCY AC092353.2 SPSB4 AL159166.1 NINJ2-AS1 AP001107.5 LEFTY2 ANKRD63 KLHL3 MKS1 LINC00880 PDZRN3-AS1 TRDN-AS1 CNOT11 PMEL AL670729.3 TBX20 SMTNL2 PTENP1-AS SUSD4 PRDM16-DT AC104971.1 AC104083.1 C11ORF21 ATXN1-AS1 GJA5 HEY2 COA5 AC126468.1 AC119427.2 USP46-AS1 HHATL PPP1R1A PDE6B AC010680.4 AC126773.4 GPR27 LINC00881 PHACTR1 TMEM163 OXCT1-AS1 SPX CCDC87 AC009133.6 INKA2 MARCHF11 MIR1915HG AC107068.2 AC018647.1 MPPED2 MIR1-1HG-AS1 AC068733.3 HIF3A SHD AC087457.1 AL451069.1 AL021392.1 AC108472.1 AC242426.2 HMGCLL1 VSTM2L SMYD1 MACROH2A2 AC098595.1 PKIA COLQ TSNAXIP1 GABRA4 C17ORF97 SH3GL3 LINC02502 AC010680.1 SYNPO2L AC008575.1 FPGT-TNNI3K PLPP7 IRX4-AS1 AC020909.2 AL136171.2 SLC35D3 AC104825.1 GNG7 NTF4 LMOD2 HAND2-AS1 AC018521.5 AC116351.1 C11ORF52 PTGES3L Z85996.3 LRRC10 CAPN3 AL157702.2 FAM133A ZC4H2 PPP1R12B CRPPA RNF207 TNMD AC068700.1 AL031123.1 AC092164.1 AC007009.1 500 genes up-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug amlodipine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/eZpZDfZQV NDFIP2 TM4SF20 RAB2A FAM8A1 IL6 ATP13A3 CCL2 MIB1 DPY19L1 TMEM65 ATP6AP2 PLEKHF2 UBE2D1 HOOK3 XIAP RAB18 TAPT1 RDX PLOD2 PDE4D CLIP4 B2M SLC30A7 ELK4 MAT2B HS2ST1 TMED5 GGH EDEM1 RAB11FIP2 LYRM5 UBE2E1 PCMTD2 LYPLA1 MTFR1 SPTLC1 TMEM30A ABHD3 FBXL3 CHMP2B PSMA2 PERP GULP1 PARD6B YAP1 TSPAN6 PNRC1 MARCKS PRKAA2 SLC16A7 RPS13 MBNL2 RPS29 TPD52 CD24 TM9SF3 PROS1 CMTM6 CREG1 MGST1 POMP ELL2 SDHD OSTC PRDX3 PLEKHA1 ITGB8 FAM169A CHIC1 PTGS2 HINT3 TRAM1 B4GALT6 TGFBR1 CYCS IMPA1 KITLG TMSB4X RAP1A DCK CBFB MLLT11 UBE2Q2 PDLIM5 CCL20 KIAA0101 CXCL3 C5ORF28 RNASE4 FGG GCH1 SLC7A11 CAV2 CLIC4 SPTSSA TSPAN13 LAMTOR3 PPP1CB TXN HPGD ITM2B SEMA3C RBMS1 SH3BGRL H2AFZ BTG1 LAMP2 LAPTM4A ABRACL MORF4L1 IMPAD1 EID1 BNIP3 RHOQ TP53INP1 DYNLT3 SMIM15 NDFIP1 PCNP LRRC58 NDUFA5 FDX1 DSTN CAPZA2 PHLDA1 RBM7 SAT1 SEC61G RPS27L SAR1B CD164 SLC38A2 BNIP3L DEK CBX3 B3GNT5 FLRT3 TMEM258 PIGF CHMP5 CRYZ ARL6IP5 WRB TMX1 YPEL5 UBLCP1 LAMTOR5 SRP9 GPR160 MRPL42 PSMD10 GOLT1B VMP1 GSKIP ANP32E RCN2 LMAN1 GNG12 COMMD8 GJA1 SYPL1 AMD1 PSMA1 RPS6KA3 LACTB2 VAMP7 SLC39A10 HMGN4 NAA50 ELOVL7 PPP3CA ABCB10 MMGT1 GLRX2 ERH SNX10 SNRPE RPL34 IER3IP1 NEK7 AGPAT5 GNA13 TMEM245 SOAT1 TMEM55A HSD17B11 PTBP3 DNAJB9 ZMAT3 TMEM47 SRSF2 NUFIP2 TMEM170B TBL1XR1 PURB MSMO1 KLHL24 C15ORF48 KDSR ZMPSTE24 GNB4 MOSPD1 CD46 ITGAV UHMK1 CD47 RPA3 SNHG5 DCP2 PCGF5 LBR GOLGA8B OTUD6B TMA16 TMEM126B ZNF566 ALG10B C10ORF32 LPGAT1 TMEM56 SMAD5 TFPI2 TIA1 BET1 STARD4 ZBTB6 SCOC ZRANB2 KIAA1033 SRGAP2C YTHDF3 GFPT1 TM6SF1 SCAMP1 SLC25A36 PRRC1 FMR1 RAB8B SRGN MMD SERP1 SRSF11 HNRNPA1 CALM2 ACTR2 IGIP SLC25A32 FGF2 RARRES1 IFNGR1 SIAH1 TWF1 AASDHPPT COX11 UBE2B IDI1 HPRT1 EGLN1 RNF11 TMEM167A TSNAX STXBP3 ZDHHC20 TMEM165 CRLS1 PI4K2B OTUD1 RAP2C TMEM9B SLC35F5 SLC30A5 RFK YIPF4 ARL8B ATP1B3 CCPG1 CMPK1 BTBD1 CGGBP1 C6ORF62 C5ORF15 C11ORF58 POLR3G ARL5A COMMD10 PAQR3 DNAJB14 NIPA2 PDP1 PTP4A1 ACSL4 BTG3 PON2 TMEM123 SOCS6 MIER1 SPRED1 WASL GLS FAM91A1 ACBD3 SPCS3 GMFB ZBED5 OSTM1 COL4A3BP FAM3C STEAP2 LIN7C KRAS CCNG2 DPY19L3 YAF2 TRIQK TMEM168 IL6ST PRKAA1 CISD2 NRAS TFPI TMEM106B LPCAT2 SEC24A UBXN4 SAMD8 ZDHHC17 AP5M1 ELMOD2 GCLM PCGF6 PHF6 SLC18A2 SGPP1 ATF2 SOX4 RRM2B TSEN15 CD2AP CCNC SDCBP IREB2 GAS5 TMEM87B NUDT21 KDELR2 HSD17B12 SDHC SLC4A7 QKI SKIL MIER3 FPGT DPY19L4 PGAP1 PTAR1 CASD1 VGLL3 PGRMC2 TROVE2 RSL24D1 CLDND1 CLDN12 TMX3 QPCT HSPA13 BTF3L4 FRS2 LIMS1 PM20D2 C3ORF58 SOCS5 CREBZF FGD5-AS1 RAB27B ARPP19 CDC42SE2 7-MAR C16ORF72 NAA30 LCOR STRN3 FOXN2 LSM5 GOPC ZXDB TMED7 KLHL28 C2ORF69 MTX3 DTWD2 STXBP5 SCAI FAM199X EEF1E1 CPEB4 SVIP BCAP29 CRIPT MZT1 STYX ECHDC1 VMA21 IFT80 TMEM41B NT5C3 ETNK1 FGFR1OP2 SOCS4 SMNDC1 ZNF770 RASSF8 LYSMD3 KIAA1586 TNPO1 PDCL PCMTD1 THAP5 CXADR LARP4 MDFIC NUS1 TRUB1 MINOS1 SNAP23 TAF9B GTF2A1 FBXO28 CPOX VAMP4 PLA2G12A EIF1AX ANKRD46 SMIM14 ERO1L SLMO2 MBTD1 ZNRF2 ZFAND6 SLC36A4 EXOC5 IPMK CDC73 RPRD1A MAP9 PNPLA8 JKAMP CRNDE FAR1 CAAP1 C7ORF73 NUDCD2 UBE2W SLC2A13 PGGT1B FCHO2 CNIH C12ORF23 C1GALT1 ANKRD36BP1 ZNF260 LYRM7 LOC100505876 MOB1B DENND1B SSR1 TWSG1 ARMC1 FAM76B ZDHHC21 ZFY MFSD8 C6ORF211 REEP3 ZDHHC2 MIR3064 MED7 C16ORF52 ZBTB41 BLOC1S6 DCUN1D4 FAM160B1 BIVM PGM2L1 LOC729852 LOC401397 SCML1 FAM73A WDR36 RAP2A 5-MAR PAR5 ALG10 SPOPL C5ORF24 OSBPL8 CCDC39 HECTD2 TXLNG2P LOC100507217 15-SEP 500 genes down-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug amlodipine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/eZpZDfZQV MYH9 AP2A2 PIK3R2 MVP FBXW5 CHPF BCAR1 UBXN6 IRF3 MAP7D1 LMAN2 SCAP UPF1 TMUB1 ABL1 PFKL ZC3H18 TUBB4B HSPB1 GGT1 GPAA1 TMEM54 RBCK1 COL4A2 SPTBN2 CTSD NUCB1 ISYNA1 CYB5R3 MFGE8 ERBB2 BAG6 POR PLD3 TRIM28 WFS1 SHARPIN TGFB1 AGPAT2 PTGES2 GFER PLEC SLC25A39 H2AFJ TRAP1 GADD45GIP1 TLN1 WDR34 WDR24 NDUFV1 SCYL1 SAC3D1 NAGLU C20ORF27 SGTA BRF1 KRT7 MZT2A KRT19 KRT8 RPLP1 SRRT ITPK1 SYMPK SLC12A9 TOMM40 PIEZO1 MBD6 LGALS3BP C15ORF39 PRKCSH HS1BP3 NUMA1 XAB2 FLNA AKT1 ZC3H7B GAA FKBP8 GNB2 LRP10 DDRGK1 MYADM CD81 TBC1D10B CYBA PPP6R1 CORO1B SHKBP1 PIP5K1C CIC LMNA SDF4 PLOD1 MAP3K11 NDST1 INF2 TKT ARAP1 CLUH ARHGDIA GRN TOLLIP PPP1R12C SYNGR2 SLC38A10 ZYX NCLN PLK1 PYCR1 MYBL2 TWF2 TUBG1 NDUFS7 SAPCD2 EIF4G1 SMTN FAM20C OPLAH PKMYT1 SNX8 MKI67 SIGIRR LRFN3 TPM2 COL18A1 COL6A2 LLGL2 FAM83H MYC PKP3 CNOT3 HMGA1 FOXM1 AGRN CELSR1 SREBF1 WNT7B BCL9L THEM6 TONSL CAPN1 PAK4 JUP CEP170B PLCD3 SERINC2 CAMSAP3 MYH14 GIPC1 SLC2A4RG SLC7A5 SLC52A2 EVPL EEF1D EPHB4 LAMA5 SLC4A2 AXIN1 LRP5 NFIC SOX12 MED25 DYRK1B ZNF628 SCAMP4 DHX34 RAB11FIP3 AP2A1 CYHR1 TNK2 SLC12A7 KDM4B MGRN1 GLIS2 PLXNB2 FBRS SCAF1 PLEKHG3 TMEM8A ATG2A MBOAT7 AKT1S1 TNRC18 EPN1 ERF C14ORF80 MCM5 XRCC3 SLC25A22 TTYH3 GNAI2 RPL8 DGKZ LRFN4 FAM129B HPCAL1 EEF2 CDC42EP1 GSTP1 EGFL7 JUNB C9ORF69 CRIP1 LTBP3 RPL18A ADRM1 MRPL28 FAM53B MXD4 JDP2 CTU2 TMEM259 EHD1 EDF1 FASN CYP2S1 MYO18A MEGF8 GUK1 FSCN1 SCAND1 CCDC85B PGLS DGKQ TP53I11 NPDC1 ZNF205 SORBS3 SEZ6L2 UBE2S POLD2 SF3A2 C12ORF57 SSSCA1 CCDC124 TSPAN4 PHLDA3 NOSIP POLR2E RUVBL2 CLIP2 PCNXL3 MVD SSNA1 TPGS1 GCAT ACTN4 BTBD2 MAP1S RAB11B LRRC45 AHNAK2 LMNB2 LIG1 HES4 ARPC1B C20ORF24 COPE BLVRB RNH1 PHLDA2 OSGIN1 ANAPC2 LOXL2 SDC3 TUBB3 MMP24 CERCAM NUMBL REXO1 IRAK1 TRAPPC5 DPP9 BSG AP1B1 FKBP2 NR1H2 ARAF EEF1A2 PRPF6 CLCN7 C9ORF16 CLPTM1 APRT ALDH3B1 STK25 MPST GTPBP6 DDX54 NUBP2 C19ORF24 IRF2BP1 XYLT2 EPHA2 NDOR1 TBL3 COMTD1 WDR81 FAM173A TRIP6 RALY DUS3L DGCR6L GPRC5C VPS18 FLII LRP3 GLI4 PACS2 MAZ LSS TTLL12 METRN FDXR NCOR2 RNPEPL1 POLR2A ATP13A1 MBD3 FASTK KATNB1 G6PD STRN4 HDAC7 FOXK2 PLXND1 PPP1R14B DAPK3 RHBDF1 SRCAP AGAP3 MICAL3 NOC2L SLC9A1 PLEKHM2 NDUFA11 ABR TBCD TSSC4 MAF1 ITGA3 UNC45A DTX2 ECE1 PLXNA1 VWA1 SIPA1L3 HIP1R TNKS1BP1 PTPRF WNK2 EHMT2 TSC2 FOXP4 AKT2 GPC1 MYO1C ABCA3 ARSA STK11 ATP13A2 DNM2 SCARA3 ZBTB17 ABCB8 IMPDH1 COL5A1 CRAT PPP1R9B LIMK1 APBA2 THAP4 PKN3 POLD1 MYBBP1A RECQL4 C16ORF59 TCOF1 GRWD1 MLLT1 ARHGEF1 MAP2K2 PLOD3 JOSD2 BCAM EHD2 BCL7C FSTL3 GPS1 PCYT2 MTSS1L ZNF579 PHRF1 RAVER1 ZNF703 HCFC1 FBXL19 CASKIN2 CACTIN ZBTB45 SAMD11 BRAT1 HAUS5 RNF40 INTS1 TMEM104 HSPBP1 ADAT3 WDR18 PRR7 MLST8 MED16 LONP1 ZMIZ2 9-SEP LMF2 PFKP FARSA SETD1A RBM10 BCKDHA HSPG2 RAI1 FBXL18 DOHH KIF1C PRRC2A PKN1 SBF1 VAV2 PRR14 PHPT1 GIT1 CIZ1 CDR2L UBALD1 CENPB ZC3H3 TAF6 MFSD10 ZDHHC8 ARHGAP39 RASSF7 PUS1 PRPF31 ZNF213 CABIN1 GTF2F1 GLTSCR2 TSC22D4 FAM195B ARFGAP1 WIZ RIN1 TRABD ATN1 FLYWCH1 TRAF7 DUS1L ZNF71 HDGFRP2 KCNC3 CCDC97 CC2D1A C19ORF21 ITFG3 FAM171A2 GATAD2A LLGL1 SLC25A6 GPR137 ZGPAT GDPD5 CROCC PVRL2 SART1 CHMP6 TSR3 FAM195A PIDD CPSF3L INO80E C4ORF48 PPP1R26 DCTN1 ZNF775 SH3GL1 MED15 ZFPL1 ZNF358 LZTS2 C17ORF70 CCDC22 KLC2 PTPN23 SPATA2L SOGA1 KIAA0195 PUF60 500 genes up-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug berbamine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/yoAOQs7qE MYH9 UBL5 CEP250 OS9 CCL2 MVP SQSTM1 UBD RPL12 RPL36 UBXN6 IRF3 HRAS IFITM3 SWI5 MYO15B UBXN1 ABL1 AATF PFKL PKM ZC3H18 GGT1 HMOX1 GRIPAP1 EIF4E2 COL4A2 SPTBN2 CTSD NUCB1 ST3GAL4 FMNL1 SFN MGAT4B ERBB2 BAG6 POR PES1 AGTRAP SIL1 SRC CCDC86 CHMP2A H2AFJ SCYL1 BCL2A1 DDAH2 CXCL1 KRT18 ASS1 RPS11 RPL41 ELF3 RPS25 RPL19 LCN2 KRT8 RPL11 RPS27 RPL27A FTL SRRT CD2BP2 OGDH MAN2B1 SLCO2B1 TNFAIP2 USF1 RIC8A IL4R DDX41 LGALS3BP SH3TC1 TBC1D9B SHC1 PRKCSH ARHGEF10L PGD VASP NUMA1 ZC3H7B PTK2B TUBGCP6 LDB1 GAA FKBP8 CD37 DDRGK1 QSOX1 TYMP PPP6R1 MAN1B1 SDF4 PLOD1 SLC16A3 EHBP1L1 TYK2 HK1 APOL2 TKT PDIA4 ARAP1 HLA-E GRN LTBR CAPG SMARCD3 CTSB LDLR RAB13 TP53I3 EIF4G1 GAPDH EPHB2 ABCD1 IFI27L2 TBC1D2 ICAM5 MAP3K6 TPM2 G0S2 SLC25A29 TJP3 PBXIP1 ABCF1 B4GALT7 ADAP1 RHOV BCL9L LAMB3 CAPN1 JUP SEMA4B MYH14 FAM83G EEF1D CLSTN1 SLC4A2 ABCA7 FPGS FAM50A SLC45A4 TFE3 CCDC9 BCL3 PLXNB2 ZNF646 SBNO2 DDR1 ZNF710 ATG2A CFB TAP1 CCDC88B KCNN4 CXCL3 C1R NMRAL1 SOCS3 NFKBIE GBP2 RHCG ADM PTGES IL4I1 ASAP3 EPHX1 PSME1 FTH1 PSME2 RPS28 ZFP36 TMA7 IGFBP4 PSMB10 EIF3G FAM129B TGM2 EEF2 NDUFA3 P4HB CYB5A ADAMTS15 NDUFA13 PRDX5 ARL6IP4 PPP1CA S100A6 RPL18 HCFC1R1 RPL35 RPS9 RPL18A PLEKHG2 DHX30 SLC39A1 CALR PQBP1 NDUFA1 EDF1 THEMIS2 EEF1G CFDP1 RPS3 SUPT5H MARCKSL1 CYP2S1 MYO18A MEGF8 RBM8A KDM6B KIFC3 ZC3H12A FGB PPP1R15A SYP TBC1D10A CLSTN3 TP53I11 PPFIA3 SEZ6L2 BCORL1 MRPL24 ACIN1 TMEM205 C19ORF70 ASL SSSCA1 DPP3 PPP1R18 C19ORF10 FAM127A NOSIP TMSB10 HSPA1A ETFB RUVBL2 NUDC SNORD104 COL7A1 IK MEA1 ITPKC PRRX2 CLIP2 C15ORF48 ATP5E RND1 HSD17B14 PRRT2 C6ORF47 GRAMD4 NNMT ATF6B SMOX TRIM21 GSDMD C7ORF49 PTMS ACTN4 XRCC1 PCSK9 SLC43A2 C6ORF141 DHX16 PNKP MAD1L1 CCDC106 TCEAL3 SNHG9 RELB TICAM1 VAT1 RHBDF2 ALDOA GNB2L1 MYL6 CLIC1 BLVRB PTPN6 RPL17 OSGIN1 FADS2 NR4A1 DNM1 CD68 PLXNB3 CERCAM C1QTNF1 HLA-H IRAK1 PSMC4 TRAPPC1 PET100 TNIP1 IKBKG NFKB2 ERP29 AP1B1 STX4 TOM1 FKBP2 IFITM10 AIP POLD4 PRPF6 VTN ROBO3 TRAF2 CREB3 CLCN7 CDC37 JMJD4 STK25 TBC1D17 CCS DDX54 XYLT2 ANKZF1 NYAP1 DLL4 WDR81 SLC16A13 VPS18 FLII GNPTG COL27A1 NUDT14 LSS ATP13A1 FLJ16779 RHOBTB2 G6PD LBP STRN4 FLOT1 PLXND1 MYO9B SNAI1 SLC39A7 TIMM13 OSBPL5 PLEKHM2 CTTN FDPS FAM214B ITGA3 TAB1 UNC45A PELI3 PLIN3 NPHS1 ECE1 SIRT6 PLXNB1 UBTF SSRP1 SMARCC2 TNKS1BP1 CYTH2 WNK2 TSC2 FOXP4 DDX27 NOTCH3 ABCA3 AMBRA1 POLR2F ADAMTSL4 DHPS DNM2 ABTB1 F12 AKR1C1 COL5A1 SYNPO RRBP1 PDAP1 PPM1G FZR1 PELP1 DHX37 TOP1MT RHOC NSFL1C PNKD SDSL POLR2L ZC3H4 KDM5C ZSWIM4 FSTL3 MYL6B CSNK1E KIF3C NDUFB8 LTBP2 PHRF1 CCDC96 MGAT5B RNF40 ZMIZ1 GRAMD1A MAP4K2 ECH1 9-SEP PFKP FARSA SETD1A AP3D1 UBE2O BCKDHA SNX33 WBP1 SUPT6H C22ORF46 POLR2J2 CHD3 ZC3H13 APBB1 CD99L2 KIF1C DBNL SCRN2 PRRC2A DDX23 SF3B2 SBF1 ICOSLG SND1 CLASRP ZRSR2 COL5A3 CACFD1 SNRNP35 ARHGEF40 FTSJ3 GPS2 IMP4 PRPF31 TLE2 CABIN1 TNXB FDX1L ARFGAP1 RILPL1 ATN1 TRAF7 CCDC97 C19ORF21 SLC25A6 PVRL2 SART1 CHMP6 DCTN1 ZNF358 KLC2 PUF60 IQCD LOC728431 POMGNT1 GPC2 WBSCR27 ATHL1 CHGB NUDT22 PTOV1 TMEM132A RPH3AL DHX38 KRI1 MINK1 ATP5SL KIRREL2 WDR46 C16ORF55 ADCK4 MED11 PRPF40B LYNX1 GRIN2D MIR4442 MLL4 TCEAL4 IQSEC2 FAM89B SGK110 CCDC64 KIAA1984 YLPM1 LOC100131691 ATP5I KIAA1967 SNAPC4 PAM16 PAF1 STK19 MEIS3 DGCR14 CTSL1 500 genes down-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug berbamine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/yoAOQs7qE NDFIP2 RTN4 RAB2A RB1 TRIM59 RCHY1 DPY19L1 UBE2K TMEM65 ATP6AP2 UBE2D1 SEPSECS RYBP RAB14 BIRC2 PRKAR2B ELK4 TMED5 RAB1A RAB11FIP2 NAP1L1 GLO1 TOMM70A CHPT1 LRRC40 LYPLA1 SLC25A40 TFAM TMEM30A NXT2 POLI FBXL3 ZFAND1 CHMP2B NAE1 CAV1 TGFB2 PERP GULP1 PARD6B RALGPS2 NCKAP1 MARCKS TPD52 MDM2 CD24 ACER3 ENPP4 TM9SF3 CMTM6 TOP2A SLC35A5 CREG1 ERI2 MGST1 NUF2 HMMR KIF14 SDHD BCAT1 IL18 BRCA2 RMI1 TTK NCAPG YES1 PLEKHA1 CHIC1 MYBL1 AZIN1 TRAM1 WDR72 CNOT6 ABCE1 MINPP1 CYCS CHURC1 APPBP2 KITLG TMEM60 DCK CBFB CENPK C11ORF82 ARHGAP11A ESCO2 RAD54B PARPBP MMS22L SKA3 BRIP1 HELLS SGOL2 DBF4 KNTC1 ECT2 KIF20B ZWILCH SGOL1 DEPDC1 MAD2L1 CENPE GEN1 C5ORF28 CCDC18 CLIC4 TSPAN13 PTGES3 LAMTOR3 PPP1CB HPGD ITM2B SH3BGRL EIF3E LAMP2 NR1D2 TRAPPC6B RHOQ TP53INP1 MBNL1 DYNLT3 NDFIP1 PCNP LRRC58 DSTN CAPZA2 TVP23B VBP1 NUCKS1 NDUFC2 PICALM SSR3 CD164 SLC38A2 DEK YOD1 MSL2 GNPDA2 HAT1 SELT TMEM33 ATP6V1C1 CFL2 UBLCP1 SRP9 GOLT1B GSKIP GNG12 UCHL5 GNAI1 SYPL1 RPAP3 NAA50 ELOVL7 AP3S1 USP1 UBE2G1 KPNA3 PAPOLA MMGT1 ITGB3BP GLRX2 PFN2 PPP1CC C9ORF41 NEK7 AGPAT5 SIRT1 GNA13 SLC25A46 DNAJB4 PTBP3 DNAJB9 CUL4B SKA2 ARL6IP1 TMEM194A TMEM170B MNS1 C7ORF60 RRAGC MSMO1 CSE1L GLMN YIPF6 ZMPSTE24 GNB4 MOSPD1 UHMK1 CD47 PPP3R1 ASNS FAM46A PCGF5 RNF139 LBR GOLGA8B PRPF39 THAP9 TMEM68 TMEM126B FAM111B ALG10B C10ORF32 TMEM56 DNA2 SLC26A2 SMAD5 HAUS6 TIA1 BET1 STARD4 ZBTB6 SCOC ORC4 SLC35A1 CD58 ANKRD49 DDX60L HNRNPU-AS1 KIAA1033 APPL1 LTN1 XPOT CCDC91 PRKACB TWISTNB ATAD5 SCAMP1 SLC25A36 CPEB2 CTNNAL1 ARL5B ZBTB33 RAB8B XPO1 CALM2 LONRF1 GRPEL2 SLC25A32 FGF2 SIAH1 RHOT1 DHX36 SCFD1 YEATS4 EXOC1 IDI1 RIOK3 EGLN1 RNF11 TMEM167A TSNAX GNPNAT1 RAB22A ZDHHC20 ACTR6 CRLS1 PI4K2B SLC35F5 SLC30A5 RFK YIPF4 ARL8B CCPG1 CMPK1 BTBD1 CAPZA1 CGGBP1 C6ORF62 ARL5A COMMD10 PAQR3 NIPA2 ETAA1 PTP4A1 TMEM123 PTPN12 ST20 GLS SPCS3 ADSS GMFB SLC5A3 ZBED5 OSTM1 ARHGAP5 LIN7C KRAS SMC4 CCNG2 DPY19L3 TRIQK TMEM168 EIF5A2 RBPJ ATG4C DRAM2 FAM133B NANP TFPI VAPA TMEM106B SLCO1B3 SESN3 FGD4 ZNF780B RBAK USP45 SLC35B3 CTBS ABCA5 ZMYM5 SHOC2 SUCO ZDHHC17 AP5M1 PPP2R5A FBXO11 CYP51A1 ELMOD2 FLVCR1 PHF6 SGPP1 PPP2R3C CCNG1 ORC3 RAD17 TSEN15 LATS1 ST8SIA4 CCNC IREB2 TMEM70 TMEM19 TMEM87B LEPROTL1 NUDT21 HSD17B12 OCIAD1 ZNF280C SKIL TMEM135 FPGT DPY19L4 PGAP1 DCUN1D1 PHTF2 CASD1 MANEA ABHD13 AEBP2 MCOLN3 GXYLT1 RSL24D1 TRPC1 CLDN12 TMX3 TMEM156 HORMAD1 IFRD1 BTF3L4 LGR4 PAXBP1 PM20D2 C3ORF58 ZBTB1 CCDC82 LRRC8B TMTC3 EMB ARPP19 7-MAR NAA30 FOXN2 TMED7 KLHL28 C2ORF69 ZNF654 MTX3 SCAI FAM199X SOS2 EEF1E1 BCAP29 STYX LRRCC1 VMA21 IFT80 TMEM41B 7-SEP NT5C3 MED21 ETNK1 EIF5 SOCS4 SMNDC1 ZNF92 EPM2AIP1 ZNF770 SNX16 LYSMD3 C5ORF51 KIAA1586 ZNF107 PIBF1 MBTPS2 UBXN2B PCMTD1 WDR5B ALG6 THAP5 CUL5 SMC6 G2E3 C18ORF54 DNAJC10 ZMYM1 PPIP5K2 ZHX1 TBC1D23 TRUB1 FASTKD1 EPT1 GUF1 SLC35A3 FBXO28 EIF1AX PPP6C RNF38 SLMO2 ZFAND6 EXOC5 GPR180 MAP9 JKAMP FAR1 UBE2W SLC2A13 C12ORF23 C1GALT1 LOC100505876 MOB1B ARMC1 ZDHHC21 REEP3 ZDHHC2 C16ORF52 ZBTB41 DCUN1D4 BIVM RAP2A C5ORF24 CCDC39 HECTD2 LOC100507217 TMEM64 CEP57 GCFC2 MTBP FAM208A SYCP2 HAUS3 TRMT13 ZNF273 SMARCAD1 SNX14 AP1S2 DESI2 COPS2 OSGIN2 SC5DL NARG2 CTDSPL2 FAM35A C17ORF104 ZNF518A METTL21D UBE3A PPP2R5E BBS10 LZTFL1 KATNBL1 SREK1IP1 ARMC10 SGTB EFHA1 MKLN1 EXOC6 TMEM48 GCSHP3 TMEM161B AMMECR1 SMEK2 GPR126 C4ORF21 SCYL2 ATAD1 LMBRD1 KIAA1430 500 genes up-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug loperamide Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/echwTogfm EEF1A1 BIRC3 IL6 HSPA5 CCL2 ERLEC1 GHITM CXCL5 ITGB1 YWHAZ ACE2 NBR1 ACSL3 SEPSECS XIAP RYBP NFKB1 PTX3 PLOD2 ADAM17 STAT1 PDE4D CLIP4 B2M SLC30A7 TDP2 FBN2 AKAP9 CXCL2 STOM EDEM3 HS2ST1 DPH5 EDEM1 NAP1L1 DMXL1 UBE2E1 ZC3H12C PCMTD2 LYPLA1 VLDLR TMEM30A CD55 CHMP2B MCL1 CXCL1 ITGA2 ASS1 CEBPD TM4SF1 LSM12 RAI14 NFIB CA8 OSMR PNRC1 RICTOR MARCKS DSG2 TCP11L2 PRKAA2 RND3 RPL39 MBNL2 LCN2 ABCA1 CEP170 SEL1L SLCO2B1 TNFAIP2 PTK2B TGFBI PROS1 CMTM6 SDC4 SCARB2 CREG1 GLRX ELL2 LHFPL2 IL18 IDH1 LIPA SCD PTGS2 B4GALT1 B4GALT5 HINT3 RMND5A RUNX2 SLC2A3 TGFBR1 IMPA1 NCOA3 APPBP2 SLC38A1 EREG DKK1 DACT1 HIF1A BCL3 CEBPB SAA1 CFB TNFRSF9 TNFSF14 CCL20 EMR1 FYB CXCL3 APOL6 KYNU IFI16 SOCS3 NAMPT GBP2 GCH1 PTGES SLC7A11 GFPT2 UBE2L6 PLAU SLC6A15 AHR CLIC4 BMPR2 SPTSSA ZFP36 EPAS1 MAP1LC3B IRF1 SGK1 TGM2 ICAM1 NFKBIA GBP3 SEMA3C RBMS1 DRAM1 EIF3E EFEMP1 BTG1 SERPINE2 LAMP2 RAP1B SERPINB9 PTP4A2 IMPAD1 RHOQ ARRDC3 TP53INP1 RPL15 LRRC58 NDUFA5 CCNL1 FEZ2 FNDC3B PHLDA1 RBM7 PHLDB2 SAT1 NRP1 SMAD4 ATP2B1 CD164 RAB5A SLC38A2 BNIP3L UTY ZC3H12A MBP KIAA1551 TNFAIP3 PPAP2B PLA2G4C GDPD1 TLCD2 MUC1 STC1 PPP1R15B FLRT3 DUSP5 IRS2 MAFF NFKBIZ ARL6IP5 TMX1 YPEL5 UBLCP1 GOLT1B LMAN1 CTSO COMMD8 GJA1 FAM96A SERINC1 MAP4K3 MMGT1 SNX10 BEX2 LRP11 NEK7 RB1CC1 SIRT1 ERO1LB PLEKHG6 DNAJB9 RSPO3 TOB1 CUL4B GPR64 CADPS2 NUFIP2 MGEA5 EFNA1 MAP1B SRI C6ORF120 INSIG1 CREBRF MSMO1 HMGCR KLHL24 PRRX2 C15ORF48 KDSR MOSPD1 ITGAV UHMK1 CD47 RASA1 SNHG5 NNMT SLFN5 IL15 AZI2 PIKFYVE IRAK2 CYP1B1 GOLGA8B OTUD6B CLGN LAMP3 N4BP2 SMAD5 SEC62 TFPI2 BET1 STARD4 SCOC LRIF1 DDX60L ZRANB2 CCNT1 KIAA1033 PCYOX1 XPOT IGFBP1 RNF145 SCAMP1 RSF1 SLC25A36 ESCO1 AFF4 PMAIP1 ARL5B C1S SOD2 RAB8B SRGN EIF1 SERP1 ERBB2IP LPIN1 IL1RAP SERPINB8 DGKE BACH1 STK17A PAPPA LAMA3 FGF2 SAA2 NCOA7 LGSN SBSPON RARRES1 PRUNE2 WDR17 IFNGR1 TWF1 TANK UBE2H IDI1 RIOK3 ITCH NPC1 CLCN3 NFKB2 TMEM167A TSNAX FKBP14 LACTB SQRDL TMEM165 ACTR6 OTUD1 RAP2C YIPF5 RFK YIPF4 MCFD2 ASAH1 ARF4 C6ORF62 BNIP2 C5ORF15 ARL5A PDP1 CLDN1 GPCPD1 PTP4A1 ACSL4 BTG3 ZNF558 SNAPC1 SLC39A8 CCNT2 PTPN12 CDCP1 GABRA5 ATXN1 PPP1R3B MIER1 LBP CCDC71L HBP1 SPRED1 ABLIM3 COG6 FAM91A1 SPCS3 NPHS1 OSTM1 COL4A3BP FAM3C STEAP2 LIN7C KRAS TXNRD1 CCNG2 YAF2 PIK3C2A PLEKHA8 IL6ST ZFAS1 ZFAND5 RAB33B TFPI TMEM106B PLD1 CTBS IL13RA1 SEC24A SAMD8 GPR137B CYP51A1 SLCO4C1 SLC16A4 CLINT1 TDO2 WSB1 SOX4 RRM2B MET RPP14 CDK7 CD2AP SDCBP OGFRL1 GAS5 ASPH HSD17B12 WTAP FGD6 DLC1 SKIL LTBP2 MIER3 PFKFB2 MAN1A2 DPY19L4 PGAP1 CPD DENND4C C11ORF54 RSL24D1 CLDN12 NABP1 KDM5B NTN4 TMX3 TCEA1 IBTK ZDBF2 C9ORF72 HSPA13 LOC100506548 IFRD1 JMY MED13 C3ORF58 CDC42SE2 FAM217B TMEM2 C16ORF72 NAA30 LCOR FOXN2 GOPC TMED7 STXBP5 SOS2 ZNF37A CRIPT STYX TMEM38B TMEM41B SLC7A2 NT5C3 ETNK1 STRIP2 ZNF770 RASSF8 LYSMD3 C5ORF51 TNPO1 DOCK4 PCMTD1 THAP5 DNAJC12 CSNK1G3 DTWD1 ANKRD29 ANGEL2 FAM126A PPIP5K2 MDFIC KLHL8 TRUB1 DPH3 TAF9B SAV1 ZNF252P FAM63B ATP2B4 ERO1L ZFAND6 CASC4 EXOC5 IPMK PNPLA8 C12ORF23 ZNF260 MOB1B SSR1 TWSG1 REEP3 ZDHHC2 ZBTB41 C5ORF24 OSBPL8 OSGIN2 KATNBL1 SGTB MKLN1 MIR100HG SLC44A1 SKAP2 SNORD80 GABRB3 HHIPL2 C12ORF39 HIAT1 RFXAP CPNE8 IL8 LRP12 PLEKHA3 LOC100506368 MR1 LINC00657 LOC100132891 ADO MTMR6 JHDM1D ZMIZ1-AS1 C15ORF37 LOC100129550 ZNF606 500 genes down-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug loperamide Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/echwTogfm MYH9 SPTB CEP250 PIK3R2 SARS2 CTDSP1 PFAS CISD3 DNAJC11 KPNA2 CDH17 BCKDK NUP62 UPF1 CCND3 EPB41L1 MYO15B ARRB2 PKM ZC3H18 KHK TUBB4B CENPF GGT1 CIT ANXA11 POLA1 CALM3 DNMT1 TUBA1C COL4A2 ANXA13 RAD23A TUBA4A PRIM1 ERBB2 EPS8L2 TRIM28 PCNT POLA2 PHB BRD4 TLN2 AAMP NUP85 MOB2 FRMD3 GFER CDK2 RAB5C SLC25A39 CDAN1 TRAP1 TLN1 FGFR4 WDR34 FN3K SAC3D1 LAS1L MYO10 KRT18 NT5DC2 UPK1B GPX2 AGR2 KRT8 TMEM109 SRRT TAGLN2 RELT SMARCD2 SYMPK OGDH NACC1 TOMM40 RIC8A GSK3A PRKCSH CHID1 AKAP1 NUMA1 GSN FLNA AKT1 ZC3H7B DDRGK1 CAD TBC1D10B SDF4 PLOD1 NDST1 TKT ARHGDIA SNRNP70 PLK1 EXO1 MYBL2 TICRR ZWINT CDCA8 TK1 LMNB1 TUBG1 GTSE1 AURKB E2F2 KIF18B CDCA5 SPAG5 BUB1B MCM2 KIF2C KNSTRN DLGAP5 ESPL1 CAPNS1 RRM2 CDC6 E2F1 BIRC5 KIFC1 KIF4A G6PC3 TPX2 ANLN NCAPH GRHPR CDC20 HJURP TRIP13 MKI67 TPI1 CDC45 ALDH4A1 KIF20A TYMS TPM2 SLC25A29 B4GALT2 CKS1B HNF1A TF CNOT3 FOXM1 IMPA2 MLPH THEM6 KIAA1522 CAPN1 PLCD3 MYO19 SLC2A4RG SLC7A5 SPDEF HR NFIC RGS3 PRC1 WDR5 RNF26 EDC4 CUEDC1 NBEAL2 KCNJ16 PLEKHG3 PRR12 GSG2 PASK RAD54L FANCI ASF1B KIF22 TCF19 RAD51 GINS2 C17ORF53 CHAF1B FAM64A IQGAP3 FAM83D FANCD2 TACC3 MCM5 MELK TRAIP CCNF NCAPG2 HMGB2 POLE INCENP CDT1 PHF19 CHAF1A XRCC3 TIMELESS ALDH1B1 UNG NMRAL1 AMBP CLDN2 MUC5B SORD CYR61 TUBA1B THRA GSTP1 U2AF2 S100A4 CRIP1 EIF3K RPS10 ARL6IP4 DRAP1 PSMB5 TUBB HNRNPUL1 HCFC1R1 CFL1 GPI EDF1 EFHD2 IVNS1ABP MYO18A ATP5J2 CD151 APOH NCKIPSD CAMK1 TP53I11 SORBS3 CLCF1 PFKFB3 PPRC1 LAMTOR2 MCRS1 ATP6V0E2 POLD2 RNASEH2A SLC29A1 ATP6V0D1 SLC25A11 APOA1BP AHCY MANBAL SSR4 AHSA1 TUBB6 NAA10 TUFM HSPA1A RAB1B HSPA2 DDB2 PRPF8 SYT13 GRB7 RANGAP1 ANKRD1 ARFIP2 DOK4 FANCG TMEM115 FEN1 CSK C2ORF72 ITGA11 ACTN4 ALDH3A1 ANKRD13B XRCC1 CPNE2 NUDT1 MCM4 FAM111B MCM7 ALYREF RFC2 PLEKHA6 LMNB2 LIG1 NCAPD3 UCP2 CARM1 RFWD3 SRRM2 ETS2 PMM1 PROCR ALDOA CNPY3 PDXK GPR56 LMCD1 INSL4 DNM1 CD70 MCAM MMP24 FANCA RHBDL3 MAFG-AS1 PEF1 SDHA TERT CELSR2 ARRB1 AP1B1 USP5 PPP5C PPP4C FKBP2 EEF1A2 SAE1 PRPF6 PSMC3 C19ORF53 CLPTM1 APRT ABHD12 ALDH3B1 SLC25A10 DBF4B STRA13 PARM1 SUV39H1 OBSL1 RAP1GAP RALY MATN2 ASNA1 FLII PHLDB1 MAZ FA2H MVK FDXR POLR2A ATP13A1 ARFGAP2 DDX39A SLC37A4 CPLX2 G6PD DBNDD1 PPDPF RRP1 MYO9B KANK2 SRCAP TBCD NASP TUBB4A WDR1 HNF1B USF2 CD320 SEMA4G DAB2IP SIPA1L3 HIP1R SH3GLB2 PTPRF EHMT2 DTYMK FOXP4 PGP MAPK7 AKT2 MYO1C SLC19A1 SLCO1B1 KAT2A SCARA3 C10ORF54 IMPDH1 BAAT SLC29A4 SYNPO MCM3 PPP2R5D PPM1G GTF3C5 PELP1 PKN3 POLD1 RCC2 MYBBP1A RECQL4 NUP188 GEMIN4 POC1A MRPS34 TCOF1 CENPO ZNF282 ENO3 ACSF2 SMC1A CTDSPL BCAM PTRF GINS4 PDDC1 NOL6 C6ORF223 RBM14 PACSIN3 PMVK JMJD8 TRAPPC2L AGFG2 PIF1 TMEM201 RPA1 TFCP2L1 MTSS1L RAB15 ZNF608 PDK2 CNP WRAP53 C1QTNF6 IGFBPL1 MGAT5B SAMD11 HAUS5 RABL6 MYRF RNF40 POP7 CPSF1 WDR62 NTMT1 VARS2 APEH PPIL2 PAFAH1B3 FARSA RBM10 ERGIC3 PADI1 ZNF428 CBX6 CHD3 HIRIP3 KIF1C DBNL IQGAP2 DDX23 PHPT1 CIZ1 PLK4 CEP128 CDR2L TAF6 PLA2G16 MCM8 CADM4 CACNB3 FAM213B METTL1 METTL13 ATN1 C19ORF21 PVRL2 SART1 CHMP6 INO80E DCTN1 SH3GL1 C17ORF70 PUF60 PTOV1 MLL4 KIAA1967 PAF1 LINC00085 HCN2 SPSB2 EXOC7 KLHL22 CCDC101 PI4KA POLR2I WDR6 FOXD2-AS1 GPRIN1 CTDNEP1 ADCY3 PPYR1 SOGA2 SNORD25 FN3KRP WHSC1 IFI27L1 DNAJC30 ACD ZNF43 WDR85 DDX11 500 genes up-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug RS504393 Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/WL74cJilp UBB DCTPP1 UBL5 CEP250 IMPDH2 UHRF1 IL6 NINL ANPEP EGR1 RPL12 EPB41L2 RPL36 THY1 UBXN1 AATF COL4A1 HSPB1 PMEPA1 NCL AP2M1 MRPS5 HMOX1 SERPINE1 PLCB3 FBL PHB2 PTX3 COL4A2 TUBA4A NCKAP5 IFITM2 SFN MFGE8 ERBB2 NT5C NDUFB9 PLAT POLA2 TIMM10 DHRS11 FBN2 PXN MOV10 PES1 CXCL2 RILP GSTZ1 TLCD1 DDAH2 PFDN5 TBCB RPL37A RPL35A MT2A CXCL1 KRT18 KRT7 RPS12 RPS11 CGNL1 RPL27 RPL41 UPK1B RPL37 RPS8 PPL RPS3A TNS4 RPL23 RPL24 RPS25 KRT19 KRT15 NDRG2 RPL19 KRT8 RPS29 RPL7A RPL31 RPL11 RPS14 RPS7 RPS27 RPL27A ATP10A TNFAIP2 ADCY7 SHC1 MICAL1 VASP FLNA SNRPB CYBA SPATA20 LMNA EIF3B EHBP1L1 EFTUD2 NRP2 PLK1 CLTCL1 MYBL2 PLEKHN1 TK1 MRPL12 LMNB1 UBE2C MYO1E LGALS1 RAB13 MCM2 ORC1 TP53I3 RRAS SMTN TPX2 OLFML2A GRHPR CDC20 IFI27L2 KIF20A MRPL51 GSTM2 TPM2 MYC APLP1 COL5A2 CKS1B RPS2 MANF OBSCN AXL PLAUR EHHADH CYP24A1 PLCD1 WWC1 KRT80 MYO19 SLC2A4RG EEF1D TMSB4X ABI3BP DKK1 SAFB BMP1 PSRC1 ZCWPW1 CCDC85C NUAK2 CFB KIF22 TACC3 HMGB2 KCNN4 PREX1 COTL1 POLE ITGB1BP2 C1R CHAF1A DPF1 TIMELESS NMRAL1 SOCS3 ARSI TNFRSF12A HAND2 PLAU SORD PSME1 PSME2 RPS28 CYR61 HNRNPM TMA7 IGFBP4 ACTG1 PSMB10 EIF3G DUSP1 TGM2 ID3 ST5 RPL3 RPLP0 RPS19 DMKN CRIP1 CPNE7 EFEMP1 SNRPD2 RPS21 ACAT2 PSMB6 EIF5A ARL6IP4 DRAP1 PFDN6 C1QBP S100A6 PPP1R14A SHFM1 RPL18 HCFC1R1 VIM RPL35 RPS9 PSMB4 SEPW1 SOD1 CCT3 SLC39A1 HN1 CFL1 COX6B1 NDUFA1 IGFBP7 MYLK LBH CCDC57 FSTL1 EDF1 RPS3 SAT1 RPS27L PIN4 NDUFB10 HIGD2A S100A13 RBM8A ANK1 TGFB1I1 TRIML2 ARHGEF25 P4HA3 SPOCK1 S100A3 TLCD2 CITED4 TNFSF12 GPX3 SNAI3-AS1 IL11 NR2C2AP PRR13 PDZK1IP1 MRPL24 MSRB2 S100A11 GPKOW POLD2 PFDN2 PTTG1 PSMB3 STIP1 COPRS NHP2 EBNA1BP2 C11ORF48 LSM7 LINC00152 GSS THYN1 NOSIP PTMA POLR2J APEX1 NELFE UQCRH CCT7 RUVBL1 AKR1B1 TMSB10 HSPA1A DHRS2 RPL32 RPL29 CUEDC2 EMC9 MRPL11 CDK4 DDB2 NUDC FKBP4 ETNK2 NEAT1 EFNA1 SRSF7 COL7A1 MEA1 HDGF CPNE1 NDRG4 LINC00116 RND1 MLXIPL TNNT1 BCL2L12 NNMT ITGA11 GSDMD LRRC23 ISOC2 PTMS ACTN4 XRCC1 CPNE2 AARS NUDT1 AFAP1L2 IL32 MCM7 ALKBH6 SNRNP25 ALYREF RFC2 LIG1 BOP1 LAMC2 TAF15 CAPN12 SOD2 TM7SF2 RPL23A GNB2L1 MYL6 CLIC1 TCEB2 HMGN2 TUBB3 MMP2 LINC00707 FCHSD1 FANCA KIF5A ACY3 ANAPC11 PET100 PRMT1 PARP1 STX4 POLD4 SQRDL PSMC5 GSTK1 STK10 CYTH1 FBLIM1 FBXO27 TPM1 PNPO APOC1 C9ORF78 CTNNBL1 STRA13 GREM1 CDH4 GGT8P AACS HMG20B BOLA1 MDGA1 ITPA PODXL PHLDB1 KIRREL3 FDXR RHOBTB2 HNRNPC NOP56 KANK2 TSPYL2 CTPS1 OSBPL5 NASP FDPS WDR74 IFT43 ARAP3 TNIP2 TRIP10 PTK7 DNPEP PRMT5 SSRP1 PTPRF EHMT2 GALNT6 DDX27 MYO1C POLR2F MRPS7 MPP2 SAP30BP PEAR1 TRO COL5A1 MCM3 BRMS1 PDAP1 PPM1G CDCA4 RRS1 TCOF1 TOP1MT DOCK2 HSD3B7 RHOC COL16A1 ENO3 NDUFS5 PDHA1 AK1 FLNB PTRF BCL7C TOMM7 NOP2 FSTL3 COMMD4 NSDHL PACSIN3 CENPT PMVK TMEM141 PIF1 ARHGEF19 THSD1 MICAL2 MRPS21 ZP3 AFAP1 NDUFB8 LTBP2 LOXL4 KCNH1 NGEF WRAP53 SAMD11 GPATCH4 NME4 SPAG7 RAB34 APEH TEAD4 RFXANK CACNG8 NOP16 CHD3 CACNG4 LAMTOR4 SF3B2 PDLIM7 NTPCR SLIT3 SLC4A3 PALD1 ARHGEF40 FTSJ3 MYOM3 ALKBH2 DBN1 PRPF31 EIF4A3 MPP1 NOB1 SLC25A6 ZNF775 ATHL1 MIR4442 PAF1 LINC00085 ACD ELFN2 LSMD1 GPR124 PROCA1 NEK8 CCDC103 ANXA8L2 C3ORF37 TTC25 REEP2 WBSCR22 CEP164 LOC100505666 SRRM3 GPRC5B LOC100506054 CNTROB EML3 LINC00842 SLMO1 CCDC12 ZNF251 PAQR7 SYNC KIAA1644 500 genes down-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug RS504393 Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/WL74cJilp NDFIP2 IFNAR1 RAB2A FAM8A1 RB1 ATP13A3 FKBP1A ERLEC1 PTEN GHITM CDH17 UBE2D3 MIB1 DPY19L1 YWHAG ATP6AP2 NDRG1 SLC46A3 RYBP UGGT2 TTN RAB18 RAB14 ATM ANXA13 BIRC2 PDE4D ALG8 TDP2 ELK4 AKAP9 EDEM3 TMED5 RAB1A MUC13 LNPEP G3BP2 DMXL1 ITFG1 TOMM70A CHPT1 TMEM30A CD55 RWDD3 FZD5 FBXL3 NAE1 SLITRK6 CP CDK2AP1 PERP NEBL DDAH1 SLC40A1 GULP1 YAP1 S100P GPX2 DEPTOR NFAT5 TOX3 RHOBTB3 NCKAP1 QSER1 FAM214A AGR2 TTC14 SEL1L TMBIM6 ACER3 TM9SF3 TGOLN2 CMTM6 SCARB2 CREG1 SLC16A1 MGST1 STS POMP CES1 BCAT1 SNX3 HEXB LIPA RAPH1 NRIP1 MGAT4A PTGS2 AZIN1 TRAM1 CNOT6 ABCD3 TGFBR1 MINPP1 SLC38A1 IPO7 GOLPH3 CBFB PDLIM5 GEN1 SFT2D1 FGL1 FGG NAMPT MUC5B SLC7A11 SLC6A15 AHR CLIC4 TSPAN13 PTGES3 PPP1CB ELOVL5 HPGD ITM2B SH3BGRL LAMP2 ZNF780A NR1D2 TRAPPC6B SLC12A2 TM9SF2 IMPAD1 RHOQ ARRDC3 TP53INP1 MBNL1 SMIM15 NDFIP1 LRRC58 ERRFI1 DSTN TMED10 PICALM SSR3 CD164 SERINC3 CNTN1 TMED2 SLC38A2 BNIP3L KIAA1551 KCNE4 FLRT3 GNPDA2 MAGT1 TMEM33 CFL2 SRP9 GPR160 GOLT1B TMEM230 PTPLAD1 LMAN1 GNG12 GNAI1 SYPL1 SERINC1 FAM107B RPS6KA3 BZW1 NAA50 AP3S1 UBE2G1 KPNA3 PAPOLA MMGT1 SEC24B GLRX2 PFN2 PRKRIR LCLAT1 C9ORF41 NEK7 RB1CC1 AGPAT5 GNA13 TMEM245 SLC25A46 SOAT1 PTBP3 PLEKHH2 SERINC5 ZMAT3 SYT13 CUL4B PDE4B SLC38A6 TBL1XR1 INSIG1 PURB RRAGC MSMO1 KLF3 YIPF6 ZMPSTE24 CD46 UHMK1 PPP3R1 LGALS8 FAM46A SPPL2A DCP2 PDK4 RNF139 MAN2A1 GMCL1 LPGAT1 SMAD5 STARD4 SCOC ZNF302 CD58 UFM1 KIAA1033 TTC3 WSB2 PCYOX1 DNAJC3 PAPSS2 GINM1 SIKE1 FEM1C YTHDF3 PRKACB ANKRD12 FMNL2 SCAMP1 SLC25A36 CEACAM1 NCEH1 PLSCR4 ZBTB33 SERP1 XPO1 HNRNPA1 PPTC7 LONRF1 BACH1 STK17A KIAA1244 RHOT1 ITGA6 POT1 ZNF655 PPA2 TIPRL IDI1 RIOK3 TBXAS1 EGLN1 CA12 RNF11 ARRB1 TMEM167A GNPNAT1 IFITM10 RAB22A CRLS1 PPCS TMEM9B SLC35F5 YIPF5 SLC30A5 YIPF4 ARL8B ASAH1 CCPG1 CMPK1 BTBD1 CAPZA1 CGGBP1 C6ORF62 DNAJB14 NIPA2 ATP7A ETAA1 C4BPA PTP4A1 EIF3J ACSL4 PON2 STT3B TMEM123 P4HA1 FGA RAP1GAP CPLX2 ST20 TPP1 RTN3 PLXNA2 PPP2CB EMC7 KPNA4 RNASEH2B PURA AGFG1 RAB6A FAM91A1 SPCS3 ADSS CPNE3 GMFB ZBED5 TRPM7 OSTM1 ARHGAP5 MEGF9 STEAP2 LPP KRAS CDC27 CCNG2 PIK3C2A TBC1D12 RNF14 IL6ST TMEM144 RBPJ DERL1 ATG4C CISD2 DDIT4L NRAS TFPI HK2 TRPC6 TMEM106B ZNF780B VCPIP1 RBAK UHRF1BP1L SNX13 CTBS ABCA5 SEC24A UBXN4 SAMD8 TRIP11 SUCO AP5M1 PPP2R5A FBXO11 CYP51A1 ELMOD2 FLVCR1 PHF6 CALU SLC18A2 NAA15 WWP1 RANBP6 CCNG1 FBXO45 RAD17 ST8SIA4 CCNC FBXW2 SDCBP IREB2 HECA TMEM87B IKBIP NUDT21 KDELR2 HSD17B12 MFSD1 TMEM135 DPY19L4 CPD DCUN1D1 PHTF2 CASD1 ABHD13 LMBRD2 MCOLN3 GXYLT1 EIF4EBP2 DOCK11 CLDN12 CEBPG JMY PDE3A HNF1A-AS1 LGR4 PAXBP1 TRAPPC8 C3ORF58 ZBTB1 C12ORF49 LRRC8B SACS TMTC3 EMB ARPP19 NAA30 RNF103 MON2 LCOR CNEP1R1 TMED7 SOS1 SOS2 CNIH4 SNTB1 ERGIC2 SLC7A2 NT5C3 MED21 6-MAR KIF5B ETNK1 WDR26 ZFC3H1 ZNF92 EPM2AIP1 ZNF770 LYSMD3 C5ORF51 TNPO1 MBTPS2 SGCB UBXN2B PCMTD1 VPS13C THAP5 CUL5 DNAJC10 ATP11B GUF1 SLC17A5 SLC35A3 FOXN3 CCSER2 FKTN FAM220A EIF1AX PPP6C ERO1L RDH10 CASC4 SLC39A9 EXOC5 GPR180 MAP9 JKAMP UBE2W C12ORF23 LOC100505876 MOB1B SSR1 REEP3 MIR3064 ZBTB41 DCUN1D4 RAP2A 5-MAR PAR5 OSBPL8 TXLNG2P LOC100507217 SYCP2 HAUS3 SNX14 DESI2 SC5DL ZNF518A UBE3A PPP2R5E BBS10 KATNBL1 ARMC10 EXOC6 SMEK2 GPR126 SCYL2 SLC44A1 LOC100216546 MAPK1IP1L NIPA1 FTSJD1 SBDSP1 POC1B FAM108C1 DIRC2 TMEM184C PREPL ATL2 KDELR3 TAOK1 KIAA1377 BAG4 CTAGE5 LMBR1 FAM135A FBXL17 DCAF10 RNF144B SNORA40 500 genes up-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug terfenadine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/JXjSyvxGy SRP19 UBL5 TBCA IL6 CCL2 RPL12 NMI CXCL5 EXOSC8 NDUFAF2 LAP3 NCL MRPS5 RAB8A FAM162A NFKB1 EIF4E2 QSOX2 IFITM2 SAP18 CHRNB1 HSBP1 UNC5CL CXCL2 NDUFAF1 UBE2I STC2 LYRM5 TSR2 TIMM44 BRI3 VAMP8 TMEM186 NDUFB6 ENY2 HOXC6 OCIAD2 H2AFY2 RPL37A RPL35A CXCL1 UQCR10 RPL27 RPL41 TPT1 RPL6 S100P RPS8 RPL38 RPS3A RPL23 RPS25 SCIN GADD45A COX7C LCN2 RPL31 RPL11 RPS14 RPS7 RPS27 TNFAIP2 DAZAP1 PGD APOL1 VKORC1L1 SDC4 NREP STAC3 RAB13 CBWD1 NDUFS4 H1F0 HEBP1 RPL26L1 SOWAHD MRPL51 CA11 KLRG1 TPM2 G0S2 CAMK2N1 IGFBP3 CKS1B RHOV HNRNPH1 MRPS36 CFB CREG2 TNFRSF9 ITGB1BP2 PSAT1 CXCL3 HOXC5 C1R FGG SOCS3 GBP2 RASL10B F3 MITD1 GFPT2 UBE2L6 PLAU HSBP1L1 CELF5 FTH1 SRSF4 PSENEN PSME2 SPTSSA SELK YBX1 IER3 HNRNPM TMA7 IRF1 HMGN1 ICAM1 NFKBIA ATP5J MRFAP1 VEGFA RPL5 NGFRAP1 DMKN CYB5A WBP5 VIMP RPS4Y1 SNRPD2 RPL26 RPL22 RPS10 NME2 DNAJC8 PFDN6 NDUFS6 NUPR1 MORF4L1 C6ORF57 NDUFB3 SHFM1 KDELR1 BRK1 PTGR1 RPL35 TSC22D3 SRP14 RPL15 NDUFA5 TRMT112 NDUFC1 HN1 NDUFA1 DNAJA1 MYEOV2 LRG1 CFDP1 NDUFA4 SRSF3 SAT1 POLR2K DYNC1LI2 UPF3A CHCHD1 DBI RPS27L MRPS18C PIN4 BEX4 COX14 MYZAP RBM8A SLC6A12 POU2F2 DDIT3 FGB PPP1R15A TNFAIP3 SAMD15 C10ORF91 PLA2G4C NGF TAF1D MAFF UBE2L3 DPY30 ANP32A PIGF SNRPG LAMTOR2 ACIN1 TXNDC17 S100A11 C7ORF55 PGAM1 TCEAL8 PARK7 BFAR CHMP4A DYNLT1 IMMP1L MAGOH EBNA1BP2 ZMAT2 VPS72 CDC26 UCHL3 ANP32E PSMC1 C2ORF74 NDUFA8 TAF13 NDUFA12 PTMA POLR2J UQCRH HOXB7 HMGN3 GTF3C6 RPP40 DCTN6 SNHG6 SEC11C BEX2 HSPA1A STAU1 FGFBP3 DECR1 TAX1BP3 TOB2 PLEKHG6 MFAP1 NEAT1 EFNA1 SNORD104 MEA1 PRRX2 BLOC1S4 MED10 C15ORF48 MAGOHB TCEB1 SNHG5 NNMT GIP TCAP RGS10 IRAK2 PDGFRL PTMS TMA16 AHSA2 PAQR6 C6ORF141 TMEM126B IL32 C2ORF76 LOC642361 SNRPA1 HNRNPA2B1 BCL10 RPL22L1 EIF5B RALB LPCAT1 FAM103A1 IGFBP1 TAF15 CAPN12 TCEAL3 C9ORF43 ORC6 ANP32B C1S SOD2 SH3KBP1 OPTN C8ORF4 SRGN SEC61B MYL6 NDUFB4 HMGN2 RPS6 COX6C RPL17 SRSF5 HOXC9 PTPRE TMSB15B RSPH1 SAA2 NUBP1 TBCE SNRPD3 RER1 TIMM21 ACP1 SENP3 SSU72 ZDHHC11 NFKB2 UXS1 STX4 NDUFB1 FKBP2 HTATIP2 TMEM165 COX20 COX19 IFT20 TOMM22 FAM32A APIP SNRNP27 FAM192A AIG1 C9ORF78 ARL8A C4ORF3 BUD31 CD99 COMMD3 CHMP3 CTNNBL1 IP6K2 BCCIP BBIP1 DNAJB11 CBWD2 HNRNPD PITPNA-AS1 MRPL33 CWC15 ASMTL-AS1 ADI1 CHGA HNRNPC CYSTM1 HSPB6 SNAI1 TSPYL2 NPHS1 VAMP2 GOLM1 DDX27 FAM227B RAB33A MRPS22 ASIC3 ITGAE FAM167B ANKLE2 RANBP1 AKR1C1 PDAP1 PSMA5 TCEAL1 RPP30 HNRNPAB RRS1 RPS4X MAP2K7 SPSB1 NDUFS5 FAM213A DYNLRB1 OAZ2 SSBP1 TOMM7 LETM2 MRPS21 ICA1 TOM1L1 C1ORF131 GPATCH4 CWC25 SNRPD1 ATPIF1 NSA2 LSM5 CACNG8 ZBTB7A LSM3 FAM104B NOP16 MED19 WBP1 SNORA57 SVIP CNIH4 POLR2J2 DERL2 PDCD5 COA6 HNRNPR SPCS2 DNAJA2 PNRC2 ARPC5L PLD6 HNRNPH3 ZRSR2 SNORD22 PHAX LSM6 GTF2A2 U2AF1L4 ITGB1BP1 LYAR MUC6 NDNL2 CHCHD7 GAR1 SCARNA22 ULK4 TSNAXIP1 NUDCD2 ATHL1 CHGB TCEAL4 CTSL1 IL8 LINC00085 LOC100506054 CCDC12 KIAA1644 SMIM7 MRPL22 LOC100505817 SF3B14 LRRFIP2 LOC100508120 LOC100129858 LINC00476 C10ORF11 WDYHV1 LOC100506123 EN2 RBMX2 NPHP1 LOC92249 TM2D1 LINC00493 DTD1 SDCCAG8 RCN3 MESDC2 NCBP2 FAAH2 LOC550643 MIR612 WHAMMP1 HOTAIR PINX1 LOC643669 MAPKAPK5-AS1 DYRK4 MST1L MIR27B POLR3F MRPS17 CSDA DZIP1L C21ORF15 LOC100130776 FLJ39051 LOC100506233 TMEM242 HABP4 C16ORF88 RPL23AP82 GOLGA6L5 LOC100505738 GNRHR2 TRAF3IP1 CCDC59 LOC150381 RPL23AP7 LOC100507463 LOC100506844 TMEM161B-AS1 EIF5AL1 PTRH2 NBPF16 LOC100506599 C6ORF203 LINC00338 EIF2S2 ERICH1 LOC283335 LOC646278 LSM1 UBAC2 SNORD36A MRPL45P2 HOXA4 EFCAB2 500 genes down-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug terfenadine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/JXjSyvxGy GLA RTN4 EEF1A1 ERMP1 IDE APC HECTD1 PTEN NUP54 SLC27A2 ATP6V1A TLR4 ANXA3 DDX1 NEDD9 GNG5 CENPF SLC46A3 WRN UHRF2 UBQLN1 ATP1B1 ARL6IP6 PRIM1 BRCA1 ALG8 INTS4 NUP98 AKR7A3 PLS3 RNLS ANO6 UBQLN2 FBXO9 DMXL1 ITFG1 MDH1 TMLHE NR3C1 ASCC1 INTU VLDLR C1ORF50 VPS13B YARS2 RBM39 ATP6V1B2 AQP11 ATPAF1 SLC33A1 MED14 ALMS1 SLC4A4 METTL23 NDUFB2 SYTL5 UTRN RPL39 TAB2 TSPAN3 STT3A PRPS1 FLNA CCNA2 OCRL ME1 C14ORF119 FRRS1 DEPDC1B EAF2 FAM72A MTCH2 BUB1B MCM2 RRM2 POLQ KIF4A KIF15 KIF11 STIL CEP55 FAM89A DTL PDGFD UPK3B ZNF266 BMPR1A TGFBR2 ZNF189 PIK3CA ZNF180 CYP24A1 AR USP32 SPDEF MCCC2 PYGO1 NKD1 SORCS2 BMP2K GMPS RAP1A IPO7 HIF1A FOCAD PRC1 NOTCH2 NBEAL2 SMC2 FIGNL1 KIAA1524 PSTPIP1 CASC5 FANCI BARD1 RAD51 CYFIP2 IQGAP3 GATM FAM83D CCNF FSTL4 NAV3 ZNF704 UQCRB HMGCS1 TXN ANAPC13 RBBP7 UQCRC2 MAT2A VDAC2 PAIP2 CCNI CCT4 SP3 HADH FEZ2 SLC25A3 C8ORF59 ZNF132 FLG NR4A3 SPOCK3 CDKN2AIP DMBX1 MATN3 FEM1B SNHG1 MSL2 NUP155 SELT VAMP3 RRM1 PJA2 OXA1L CRYZ CNOT10 BRE TMEM14A NOP58 ACTL6A PCNA MSH2 ZW10 SLC25A5 CDC16 UXT PVRL3 MMADHC SEC24B CERS2 IPO5 GEMIN6 GEMIN5 LDHB RPS6KC1 ATP2C1 AFTPH INTS6 NCOA4 AASDH E2F7 SYT13 GPR64 TMEM47 LRRC3 METTL25 KRBA2 HACL1 KIAA0895 GABPB1 CD46 ME2 ZNF211 ZNF671 RDM1 SLIRP ABHD10 GCA USP25 FAM46A SPPL2A TDRD7 ALG9 HLA-DMB RNF182 KIAA1279 MAN2A1 TPR GLIS3 KDM5A NDUFS1 IGSF11 XRCC4 PRKACB RFWD3 RFX7 CDK17 SLC35E2 SEC31A GLUD1 IRS1 UQCRFS1 RAB31 SF3B1 AKAP11 SON PUM2 ACTR3 ADD3 ATF7IP ROR1 TECTA AMDHD1 RAD21 TRIM32 TIMM23 GTF2H5 USP14 TFEB PIAS1 ATP2A2 MAP3K7 ESD COPG2 PLRG1 NUP153 SLC35F5 NNT CLTC ARF4 ABHD5 FAM188A CEP63 ZNF558 PLA2G4A HTT PCDHA12 ACSL1 RTN3 HBP1 SPRED1 ANKRD17 SMAD2 KAT2B TCTN3 PDE3B GSPT1 ACVR2A ZNF81 NUP160 SLC22A3 LPP SPINK13 FERMT1 SRD5A3 TTC30A DAPK1 SPG11 PIK3R4 DDIT4L ZFAND5 APAF1 TRPC6 SLC30A1 PDCD6IP SESN3 HPS3 TRAPPC11 ZNF627 ZNF17 RSC1A1 PROX2 AP1G1 BAAT CYP2R1 RANBP6 BIRC6 ANAPC1 GPN1 XPO5 NUP205 SPAG8 NUP188 SLC11A2 TMEM14C TXNDC9 COX7B OXR1 SYNJ1 RMI2 DARS2 IARS2 ATP5B OSBP FAM179B USP24 SRPRB RNF111 FNDC3A RBM14 LGALSL STRBP TBC1D5 TFCP2L1 ANKRD50 LANCL1 CPD SLK TUSC3 ZNF608 EIF4EBP2 LRRC8C ZNF697 KDM5B QPCT ZFP90 ANKRD28 ADPRM GPRIN2 SP9 TDG ADNP2 ZNF148 MED13 BTBD3 RBM15 PDPR FBXO34 DCLRE1A SPTY2D1 ZZZ3 MON2 RALGAPA1 BAZ2B NMD3 C14ORF2 HSPG2 ZXDB TUG1 RGMB MGST2 TRIP12 ZNF281 ZNF614 AP2B1 HEATR5A KLHL2 ATP8A1 RPS6KA6 EFR3A BROX WDR19 ATP11B MLH3 TBCK LRRC28 KIAA0196 STRAP MINOS1 RBM45 NUP35 SMG8 NBAS MCM8 NHLRC2 ELF2 TMEM170A COMMD7 SSFA2 EXOC6B C15ORF41 POLR1B XPO7 CMC4 FAM134B ZNRF2 TMEM185A CNIH 5-MAR PPP2R5E SLC44A1 PPYR1 ZNF43 SBDSP1 DIRC2 KDELR3 FBXL17 FER FAT3 ZNF559 SLC10A4 KIAA1432 CEP97 KIAA2018 DLD PALM2 ATXN10 C5ORF42 LOC643201 PLCH1 ZNF773 CDKL2 ZNF761 ZNF443 BSN ADNP ZNF706 ZNF165 SLC35B4 FANCM NUPL1 FBXL14 FIGN CNOT1 LOC100289187 DNAJC13 DPAGT1 DIS3 HEATR2 SPIN3 CCDC176 KIAA1009 PCDHA2 MKI67IP PKD1P1 CRYBG3 PHTF1 SPATA18 POLR2M PEX26 SNORD31 NPAT ZNF551 FAM120C CORO7 PAK1IP1 USP47 ARMCX5-GPRASP2 SNORA61 MRRF WDR47 LOC100128288 CARNS1 ZNF530 10-SEP LINC00174 ZNF611 FBXO30 FUT10 FMN2 RTN4IP1 SGK196 ZC3H12B PQLC3 LOC440434 ZNF658 SRRD KIAA0368 NR2C1 JAGN1 MIR4664 AKAP6 SBDS HEATR5B ZNF419 TMEM87A MYLK4 KLHL9 ZNF134 TTC37 ZNF616 ELP2 C9ORF163 LPHN2 PCDHGB3 MTMR4 MED31 CAND1 500 genes up-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug trifluoperazine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/dCxlp1AnK CEP250 CES2 TBCA UHRF1 CCL2 COL6A1 FBXW5 RPL12 BCAR1 RPL36 MAP7D1 UBXN1 ZC3H18 TUBB4B ZBTB7B ASPSCR1 HSPB1 RAB8A RBCK1 FBL DNMT1 COL4A2 CTSD RAD23A IFITM2 CYB5R3 BAG6 POR PLD3 MEPCE BRD4 TGFB1 SRC UBE2I CHMP2A PLEC RAB5C TSR2 ATAD3A TIMM44 H2AFJ SF1 RPLP2 TPT1 RPS8 RPL38 RPL23 RPS15 KRT8 RPLP1 RPS14 RPS27 FTL SRRT NACC1 TAOK2 GLYR1 PIEZO1 KSR1 MBD6 LGALS3BP DAZAP1 PRKCSH MICAL1 PGD NUMA1 AKT1 LDB1 GAA SF3B4 FKBP8 SNRPB GIGYF1 LRP10 DDRGK1 CYBA PPP6R1 CORO1B PIP5K1C CIC LMNA SDF4 SLC16A3 EHBP1L1 INF2 PDIA4 ARAP1 ARHGDIA SLC6A6 SNRNP70 PPP1R12C SLC38A10 ZYX NOL3 NDUFS7 RAB13 ATP6V1F EIF4G1 CA11 TPM2 G0S2 COL18A1 COL6A2 KLF16 CHTF18 PKD1 AGRN BCL9L ITGB4 PLEKHH3 CAPN1 PAK4 JUP SCRIB SEMA4B GIPC1 RHPN1 LAMA5 SLC4A2 LRP5 NFIC MC1R CDK2AP2 ABCA7 RGS3 SAFB MAFK DVL1 SOX12 FAM50A MED25 BCL3 ZNF865 CEBPB RAB11FIP3 AP2A1 RNF44 TRIM8 TNFRSF1A MGRN1 PLXNB2 FBRS MNT ULK1 GLTSCR1 SBNO2 MIDN LRCH4 AKT1S1 TNRC18 EPN1 PRR12 ERF SOCS3 SLC25A22 TTYH3 FTH1 RPL28 PFN1 ZFP36 RPL8 DGKZ IER2 YBX1 LRFN4 IER3 TMA7 IGFBP4 ATP6V0C EIF3G FAM129B TGM2 EEF2 ID3 JUNB WBP5 CPNE7 NME2 ARL6IP4 DRAP1 PFDN6 NDUFS6 HNRNPUL1 JUND KDELR1 RPL18 RPL35 OAZ1 ADRM1 TALDO1 PIM3 CALR HN1 FXYD5 ARF1 MXD4 EDF1 FASN SUPT5H CYP2S1 KIF26A MEGF8 FSCN1 PIN4 SCAND1 MIEN1 FBF1 KDM6B AKAP17A PPP1R15A S100A3 VASN NPDC1 FOXK1 ZNF205 SEZ6L2 NAT8L C17ORF96 TOR4A BBC3 UBE2L3 UBE2S LAMTOR2 WBP2 ACIN1 RBM42 ZNHIT1 IMMP1L CCDC124 LSM7 PPP1R18 FAM127A PTMA POLR2J SSR4 HOXB7 LDOC1 HSPA1A RPL29 ARHGEF18 CNFN LENG8 COL7A1 SNAPC2 PRRT2 PCSK1N NNMT LMTK3 STK32C CSK PCED1B SMOX TPGS1 ISOC2 PTMS ACTN4 BTBD2 PRKD2 LENG1 ANKRD13B ALKBH6 METRNL LMNB2 MLF2 TAF15 TCEAL3 SRRM2 CSTB C20ORF24 COPE UQCR11 RNH1 OSGIN1 DNM1 TUBB3 CERCAM C1QTNF1 NUMBL NUBP1 TRAPPC5 SSU72 PRMT1 BSG TMEM11 PLBD2 FKBP2 NR1H2 EEF1A2 ZNF629 AP5Z1 CLCN7 ARL8A CLPTM1 CD99 ALDH3B1 DDX54 ANKRD11 C19ORF24 ZFHX2 NDOR1 DMPK MEF2D MZT2B WDR81 SLC16A13 FLII TSTA3 TRAPPC6A GLI4 PACS2 MAZ COL27A1 ZNF219 NCOR2 POLR2A MBD3 FASTK MFSD12 RHOBTB2 ALDH16A1 G6PD PPDPF FOXK2 MYO9B AGAP3 TSPYL2 STARD3 NOC2L TCF25 CTTN CCDC130 PHLDB3 PPARD TRIP10 DTX2 USF2 LRPAP1 ECE1 CDC34 SIRT6 EWSR1 SMARCC2 SIPA1L3 TNKS1BP1 CYTH2 WNK2 EHMT2 MEN1 DDX27 PITPNM2 MFI2 GPC1 HSF4 STK11 SPHK2 DNM2 ZBTB17 COL5A1 PPP1R9B LIMK1 RRBP1 APBA2 PDAP1 REXO4 PRCC PELP1 CCDC137 MLLT1 MMP15 NFKBIB MAP2K2 PLOD3 COL16A1 MMP17 MAP2K7 SPSB1 JOSD2 KRT81 BCAM EHD2 BCL7C ATXN2L ZC3H4 RUSC2 ZSWIM4 BAHCC1 FSTL3 MFSD3 C7ORF50 SAMD1 NFIX ZNF579 PHRF1 RAVER1 ZNF703 HCFC1 FBXL19 GTF3C1 ZNF444 SAMD11 RABL6 INTS1 HSPBP1 RHOT2 NR2F6 ZMIZ1 GRAMD1A WDR18 NDUFS8 MED16 PFKP FARSA SETD1A ZNF598 SNRPD1 ATPIF1 NCKAP5L ZBTB7A RAI1 ZNF428 CBX6 HOOK2 DOHH CHD3 DUSP23 KIF1C SAFB2 SBF1 LUC7L2 CLASRP CIZ1 C1ORF35 UBALD1 DMWD CENPB ZC3H3 LSM6 KCTD13 ARMC5 DBN1 PRPF31 ZNF213 GTF2F1 PEX14 GLTSCR2 MKL1 TSC22D4 ARFGAP1 WIZ VSTM2L ATN1 HDGFRP2 CCDC97 GATAD2A SLC25A6 ZGPAT ZNF775 ZNF358 C17ORF70 PTPN23 ATHL1 TMEM132A KRI1 MINK1 GRIN2D MLL4 TCEAL4 ATP5I PAF1 MEIS3 CTSL1 ERICH1 TBC1D22A CDC42EP4 SYCE1L FLJ22184 MICALL2 BTBD19 SOLH PTRH1 HAGHL CSNK1G2 PRAF2 MLL2 SSBP4 FLYWCH2 DLGAP4 SAMD4B TIGD5 PALM C9ORF114 ZNF362 TESK1 LEPREL2 CHERP SIX5 GHDC ENGASE C1ORF86 ZNF777 500 genes down-regulated by SARS-CoV-2 in A549-ACE2 cells from GSE154613 SARS-CoV-2 infection of A549-ACE2 cells treated with drug trifluoperazine Source paper: https://www.biorxiv.org/content/10.1101/2020.07.12.199687v1 BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/dCxlp1AnK RTN4 ERMP1 ATP13A3 IDE PTEN YWHAQ ETFA COPB1 ATP6V1A MIB1 DPY19L1 RNF2 YWHAB ATP6AP2 WRN RYBP UHRF2 CALM1 UBQLN1 AGPS RAP1GDS1 ATM PLOD2 B2M BRCA1 ALG8 RARS SBNO1 PLS3 ANO6 SLC30A6 PAICS DMXL1 ITFG1 MDH1 GLO1 NR3C1 USP34 LRRC40 LYPLA1 SLC25A40 TFAM TMEM30A POLI CHMP2B PSMA2 POLR2B PERP METTL23 TSPAN6 NCKAP1 FAM214A RPL39 MBNL2 RPL7 TAB2 TSPAN3 PRPS1 ACER3 TM9SF3 ME1 SLC35A5 CREG1 ERI2 MGST1 ARHGAP29 ALCAM KIF14 UACA SDHD DLGAP5 CDK1 CCT8 HEXB ANLN CEP55 OSTC LIPA NCAPG CHIC1 MGAT4A AZIN1 ATR TRAM1 WDR72 ZNF189 ABCD3 ABCE1 IMPA1 FZD3 KITLG IPO7 UBE2Q2 SMC2 FIGNL1 KIAA1524 FBXO5 CASC5 RAD54B FANCI KNTC1 ECT2 PBK CENPI DEPDC1 FYB GEN1 SLC7A11 UQCRB PTGES3 HMGCS1 TXN ARL2BP KLHL5 ANAPC13 ITM2B SH3BGRL EIF3E MAT2A LAMP2 VDAC2 TM9SF2 MATR3 RHOQ SP3 NDFIP1 DHX15 LRRC58 TOMM20 HSPH1 RAB11A CAPZA2 TVP23B SUB1 USMG5 EMC2 NUCKS1 NDUFC2 C8ORF59 SSR3 ATP5C1 SLC38A2 BNIP3L DEK KIAA1551 LRRK2 TIPARP HAT1 SELT PSMA4 VAMP3 RRM1 ASNSD1 GALNT7 UBLCP1 SRP9 MRPL42 GOLT1B PAN3 MRPS35 PCNA PTPLAD1 RCN2 NUP37 SYPL1 FAM107B RPS6KA3 LACTB2 VAMP7 TMPO UXT ABCB10 PVRL3 KCTD9 KPNA3 PAPOLA MMGT1 EPRS MMADHC IPO5 STAG2 HSPE1 EXTL2 SEC23A NEK7 RLF GNA13 ATP2C1 MALT1 HSD17B11 PTBP3 HSPD1 TMEM47 SLC38A6 NUFIP2 MSMO1 HMGCR CSE1L GLMN ATAD2 CD46 ITGAV UHMK1 CD47 NEDD1 ME2 PIGW PPP3R1 RPAP2 GCA SPPL2A ZUFSP PCGF5 RNF139 GOLGA8B FAM111B KIAA1279 MPHOSPH9 TMEM56 DNA2 SMAD5 SLC35A1 KIAA1033 TTC3 SPAST LTN1 XRCC4 PRKACB TWISTNB ANKRD12 SCAMP1 RFX7 CTNNAL1 SMCHD1 ZBTB33 UQCRFS1 SF3B1 XPO1 PUM2 ACTR3 FGF2 AIMP1 DHX36 RAD21 FBXL5 VTA1 TWF1 SCFD1 PPA2 TRNT1 SACM1L RANBP2 USP14 CDK6 TAX1BP1 ESD UGP2 PLRG1 AK3 RAP2C UBA6 SLC30A5 RFK GALNT1 PRKRA ARL8B CMAS ATP1B3 CLTC BTBD1 ARF4 CGGBP1 C6ORF62 ARL5A PAQR3 AHCTF1 U2SURP USP53 PON2 CEBPZ STT3B WDR75 DHX29 SMIM13 HLTF ZMYM2 ZNF680 MIOS NBN HBP1 SPRED1 TRIM13 GLS KPNA4 GSPT1 AGFG1 SPCS3 CPNE3 GMFB SLC5A3 TRPM7 ARHGAP5 RAB23 TRMT1L SLC22A3 PIK3CB CDC27 SUZ12 SMC4 PGM3 DPY19L3 PIK3C2A RNF14 SPG11 DRAM2 TFPI TMEM106B SLCO1B3 PDCD6IP ZNF12 GIN1 AP4E1 SNX13 ABCA5 LRPPRC UBR3 PPP2CA SEC24A AP1G1 SUCO FBXO11 SLC18A2 SGPP1 MTDH BCLAF1 BIRC6 CCNG1 LIN9 ORC5 RAD17 TSEN15 NUP205 ANAPC4 SDCBP IREB2 TXNDC9 GAS5 TMEM19 NUDT21 DARS2 KDELR2 IARS2 HSD17B12 MFSD1 FNDC3A ANKRD50 LANCL1 PTAR1 SSX2IP TUSC3 CAPN7 PHIP MFAP3 MANEA CD109 MCOLN3 RSL24D1 CLDND1 AGTPBP1 TMX3 HSPA13 ANKRD28 LGR4 TDG MED13 SACS MAP4K5 CHML EMB ARPP19 7-MAR RALGAPA1 FOXN2 NMD3 C14ORF2 TUG1 TMED7 KLHL28 BRWD1 PRKAB2 FAM199X SOS2 EEF1E1 ARL4A DENND4A C1GALT1C1 BCAP29 CENPQ IFT80 SNX5 MED21 ETNK1 EIF5 CHD9 EPM2AIP1 C5ORF51 ZNF107 TNPO1 HEATR5A G2E3 CCP110 RPS6KA6 DNAJC10 EFR3A PPIP5K2 ATP11B TBCK KIAA0196 STRAP MINOS1 NCBP1 CHM BRWD3 XPO4 SLC35A3 METTL15 FKTN DDX3Y CMC4 MBTD1 ZFAND6 GPR180 JKAMP FAR1 CNIH C1GALT1 ARMC1 FAM160B1 BIVM LOC401397 RAP2A ALG10 C5ORF24 HECTD2 LOC100507217 15-SEP CEP57 DESI2 NARG2 FAM35A ZNF518A EXOC6 TMEM48 SCYL2 FTSJD1 POC1B ATL2 TAOK1 LMBR1 SNORA40 DLD ATXN10 ZNF761 SLC35B4 DNAJC13 DIS3 MKI67IP CRYBG3 NPAT PAK1IP1 USP47 10-SEP FBXO30 NR2C1 SBDS HEATR5B TMEM87A KLHL9 TTC37 MED31 CAND1 ZNF181 C6ORF170 C2CD5 TUBD1 LOC100506710 PRKCI POC5 ZNF765 FANCB ZNF638 AGL PAFAH1B1 KIF2A PRPF40A LOC201651 CCDC132 ZNF529 GPD2 TTC19 500 genes up-regulated by SARS-CoV-2 in human pancreatic organoids from GSE151803 SARS-CoV-2 infection of human pancreatic organoids Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/GTPj8HM9k UBB CCL2 TMEM37 MVP STAT3 UBD SPINK1 TNF IRF3 CXCL5 TSPO IFITM3 HLA-B ECSIT HMOX1 UBTD1 GPX1 FLT1 PTX3 HLA-C PLOD2 TST HLA-A IFITM2 AGT TMEM176A B2M SFN TMEM173 UNC5CL CXCL2 SIL1 TGFB1 MOB2 AGPAT2 PTGES2 PKIG ABHD11 HPN LRRC61 ARL4D SERPING1 TFF3 MT2A CP CXCL6 KRT18 OLFML2B CEBPD NINJ1 TM4SF1 LSM12 HES1 CNTN5 ELF3 CA8 MZT2A SLC2A1 DLGAP1-AS1 KRT19 WDR38 KRT15 KRT8 FTL AQP3 LGALS3BP SNRPB LRP10 TYMP PROS1 CYBA B3GNT7 PLEKHO2 SLC16A3 HK1 APOL2 HLA-E SYNGR2 TWF2 RAB20 SPR IGFBP2 LGALS1 ACCS GPNMB ITGA1 GALK1 SMTN C2 PDIA5 ABCD1 ANKLE1 LDHA ABCB1 EBF4 G0S2 A2M S1PR5 GADD45G GLYATL1 MMP11 GADD45B AQP10 CISH GAD1 MMP25 CLDN4 CBLC SSH3 SEMA4B CDH3 EEF1D WNT4 MEF2C FOXL1 CBLN4 HPX MC1R UPP1 PTHLH DACT2 BCL3 TNFRSF1A SBNO2 GRAP2 IRF7 CFB NLRC5 TAP1 OIP5 PPM1N CD72 COX7A1 PRSS22 C3 PSMB8 APOL6 MDFI SUCNR1 SOCS3 NAMPT ADM SERPINA3 HAS2 SOCS1 C5AR1 UBE2L6 IL24 UBA7 FST GLT8D2 NEGR1 ANGPTL2 SCN3A SCN7A PSME1 ZFP36 SEPT4 IER3 IRF1 PSMB10 TGM2 TXNIP ICAM1 DTX3L NFKBIA TPPP3 CDC42EP1 EGFL7 RIPPLY3 JUNB NPNT RPS19 EFEMP1 RPL10 LYZ SERPINE2 PPIB TMEM176B C10ORF10 IFI30 PIM3 SLC39A1 ROMO1 ADAMTSL2 CDO1 GYG1 GNS PCOLCE EFHD2 KIF26B ZC3H12A TPTE2P1 SELM RGS4 AOX1 SLC38A4 CSF1 KCNE4 GPR111 VIP KLHL41 SPON2 S100A3 CALB2 BHLHE40 NFKBIZ C19ORF70 ASL TFPT HSPA1A DHRS2 TSEN34 YDJC SLCO2A1 ADCY8 NEAT1 ID1 EFNA1 ADRA2C TPST2 ID2 MMP9 HABP2 RND1 IL1R1 TMEM115 B3GNT8 BCL2L12 NNMT TAP2 MFAP4 CELA3B TLR2 IL15RA SMOX GSDMD TRIM69 PLK5 C19ORF25 SLC27A1 CPA5 SSTR5 SNHG11 PRSS2 VNN1 LINC00324 LAMB2 C19ORF66 PAPSS2 RASL10A ETS2 CEACAM1 PLK2 BTN3A3 PMAIP1 HCP5 GPR115 SOD2 VNN2 IL7 SERPINA1 SEC61B MSRB1 COPE RPL17 LPAR6 BMF KLHDC8B ITPRIPL1 CBS TRIB1 DAPK2 GJB6 SEMA7A CFC1 GALNT9 TUBB3 MIR503HG CARD11 NKAIN4 CSMD2 FAM169B SCN5A C1QTNF1 FAM65C TACR1 VNN3 PLXNA4 C4B ELFN1 TNFRSF25 ANAPC11 C8B C17ORF62 TRADD HHEX FOXJ1 TNFSF11 XBP1 SYK BAK1 POLD4 EEF1A2 MIR7-3HG VTN CHRM3 AURKAIP1 C9ORF16 C11ORF71 THAP7 NUBP2 IRF2BP1 FFAR2 ECHDC2 THBS3 RAP1GAP BOLA1 TRIP6 TRAPPC6A THOC6 AMDHD2 ALDH16A1 BCL6 CCDC114 JAK3 FLOT1 NFATC4 PLEKHM2 ABLIM3 SIVA1 SPHK1 RIPK4 CRYBA4 CRYBB1 MTUS1 PLEKHF1 CALCA ADCYAP1 ECE1 KCNJ5 CEL CDKN2A CER1 GLYATL2 EYA2 VWA1 PROM1 SST SLC9A9 EVA1A SLC8B1 IL13RA1 FOXA3 SERPINA11 TDO2 S100B TGIF1 SYNPO MTFP1 HOXB4 NEIL2 RPUSD1 LAPTM4B PODN MAPK4 HSD3B7 RHOC SPSB1 CYB5R4 TMEM51 HDHD3 SDSL JOSD2 FBXO2 HS6ST1 HES6 FEZ1 LOXL4 GPD1L CNP ZDHHC12 SAMD11 OSBPL10 A4GALT GRAMD1A UNC5A C2CD4A TEAD4 PRRG4 EMILIN1 PID1 C1RL LAMTOR4 NRSN2 THAP3 TM4SF18 PHYKPL SCN1B KCNK1 CCDC162P MAN1A1 LRP4 COL15A1 PLA2G16 BLOC1S3 FAM195B SDHAF1 TFAP4 NOB1 RDH10 ASPHD2 SUSD4 PPP1R1A TMEM163 SLC25A6 CHMP6 IQCD ATHL1 NUDT22 ADCK4 PRPF40B EML3 RCN3 FAAH2 FLYWCH2 LOC101928111 RP11-538P18.2 CHRD LOC102723465 KIAA1751 CCL4L1 LOC100996634 SLC18B1 CXORF40A MAP6D1 SERTM1 KCNT2 C1ORF173 KLHL25 KCNK15 C2CD4B PCDHB2 GPR85 MPG SPACA6P RNF144A-AS1 FLJ38668 MIAT ZNF503-AS2 LOC101927777 ME3 SOX1 GRM4 LOC100129223 DTNBP1 C11ORF31 PTGES2-AS1 ELMO1 KCNA4 SLC22A31 LRRTM2 SPEF1 HTR7 LOC102723863 LOC100130417 JADE1 RAB42 ASCL1 ABLIM2 RP11-277P12.20 ZNF385D LINC00242 ROM1 FLJ45743 TSHZ3 LOC102724312 CCR10 PSPN GALNT9-2 LOC102724800 TSSK3 GDAP1L1 RP11-10A14.5 LOC100287413 PPAPDC1A LINC01122 LRRTM1 IKZF4 CNTNAP1 LOC102724124 HAPLN1 LOC101929748 C12ORF44 LOC101928891 CLIC6 LINC00673 PCDHB9 FAM69B MIIP 500 genes down-regulated by SARS-CoV-2 in human pancreatic organoids from GSE151803 SARS-CoV-2 infection of human pancreatic organoids Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/GTPj8HM9k CEP350 EPS8L3 DPP4 ANPEP APC MDN1 MALL SLC1A1 MACF1 DAAM1 MYO1A FABP1 PDZD3 CENPF ANXA13 PDE4D FBN2 MEP1A AKAP9 EPHX2 EPB41L4A TMEM236 RAB11FIP2 ZC3H12C NR3C1 ARHGEF12 USP34 APOOL KLF12 MPP7 LIFR ALDH6A1 ASB9 NBEA PCLO TSGA10 ENTPD3 ADCY2 NR4A2 COBLL1 NEK10 KIF21A RALGPS2 LMO7 PEAK1 FREM2 TRIM2 PLCE1 QSER1 FNIP2 PLCB4 ZNF507 BDP1 GCNT4 AIF1 ZC3HAV1L ZBTB20 ZNF462 ARID5B TTC22 CD101 GAS2L3 KIAA1958 MACC1 KCTD3 SPAG5 TMTC1 RNASE1 HGF AMPH UNC13B CDC42BPA RAPH1 KCNMA1 SLC9A7P1 KY SGCD ITGB8 C16ORF54 PTGDR2 SPON1 AKAP12 KLF2 CACNA2D2 SLC30A4 ABCC8 CGREF1 PLCXD3 ABCC4 ABCC2 MITF FAM20A SLC9A2 CLU NAV2 SLC8A1 CASR PAX6 SYNPR CYSLTR2 IL10RA LANCL3 STAT4 RYR2 SLC7A8 GDPD2 PCDH20 AAK1 DCDC5 LGI3 FGG PTPRT PDE2A EPHX1 CDH22 ATP2B2 TMCC3 MYH10 SLC12A2 LRRC58 EIF4E3 WNK1 PHLDB2 PREX2 ATP2B1 ACADSB SCML2 PTGER3 NR4A3 ASXL3 SPOCK3 NLGN1 GPRIN3 KCNV2 TET1 ESRRG COL21A1 DCC TRPC7 EGFEM1P TTR STC1 DUSP5 APOM UGT8 RPS6KA3 LCLAT1 TMEM245 ERO1LB OGT MAP1B AKR1B10 FAM129A PTPRD DIAPH3 BTBD11 LPPR5 PSD3 MRAP2 HS6ST3 C2ORF72 NDST3 FAM46A PDK4 RHOH BZRAP1-AS1 CSMD3 N4BP2 LPGAT1 SMG1 LONRF2 NHS NEB SHPRH C3ORF80 XRN1 DDX60L KCTD12 SLC47A1 ZBED6 UTP20 PKHD1L1 ONECUT2 OSR2 DUSP4 NOSTRIN ST6GAL1 CSRNP3 SPTSSB GRIN3A NAPEPLD CDH12 FRY SERPIND1 APBA1 KIAA1549L UNC80 COL12A1 ADAM12 SCGN CHRNA2 ATP1B2 MYO16 GPR98 GPR50 KIAA1244 PCP4 CORIN PRUNE2 WDR17 MTSS1 RET KIT DICER1 SOX5 EEA1 TIMP3 PCSK2 ZBTB38 PRKCA DAB1 STXBP5L C21ORF62 ACBD7 AHNAK EPHA4 PHC3 HELZ TSPAN1 DYNC2H1 ALDOC GOLGA4 KCNC4 STOX2 NLGN3 EML5 SYNE2 MSI2 CACNA1A KCNH7 VPS13D ITPR1 FXYD6 KAT2B LRP2 PPARA DGKG LIPC SLC5A3 PRKCE ACVR1C APOB SYDE2 MEGF9 DGKI STEAP2 LPP ID4 SLC30A8 RFX6 SLC9C1 KMT2C PRSS12 NRXN1 EPB41L4B FXYD3 NF1 INHBB GCNT1 CYP3A5 OPRK1 FER1L5 USH2A TMEM144 GCG BHMT IAPP NPAS4 LEPR SLC30A1 SESN3 FGD4 ZKSCAN8 CTH ABCA5 UBR3 ADH1A ABCB4 TUBB1 GCLM OSBP2 DIO1 KLB SLC18A2 RFX3 NIPAL1 RGS6 BIRC6 MT1G PLCG2 KRT81 ASPH BCKDHB PEG10 USP24 LYST VWDE GPATCH2L PDZD2 RAB11FIP1 MAOB MYSM1 SLC44A5 REV3L DZIP3 MAP7D2 PTAR1 TMEM131 ADAM23 FAT4 VWA8 VGLL3 DENND4C SRGAP3 KIAA0319 ANK2 ZDBF2 CLMP IGFBPL1 MKL2 DMXL2 PHLPP2 MYO5A PHACTR2 SACS RALGAPA1 LCOR VPS13A PDIK1L DIRAS2 HECW2 TTLL7 SCAI RPPH1 CPEB3 RNU2-2P ZNF441 CPEB4 MACROD2 PPP1R26-AS1 PPM1L TMEM117 SYNPO2 TRPC4 PRLR IQGAP2 FAM126B CEP85L KIAA2026 CHD9 NID2 FRAS1 SFMBT2 PDK3 VPS13C ATP8A1 ANKRD29 FSIP2 NDNF ARHGAP26 TSPAN2 ZNF652 COLCA2 BPTF NKTR NHLRC2 KDM7A FAM63B KIAA1109 C1QL1 CLOCK ATP2B4 DOCK9 RORA AFF1 LDB2 MSS51 STARD4-AS1 COLQ CRNDE MOB1B CHGB ZNF518A TAOK1 C5ORF42 DNAJC13 CRYBG3 HEATR5B TTC37 AGL GPD2 C7ORF76 C1QL3 LINC01004 LOC101928641 RBM5-AS1 CPNE9 GUCY1A2 CACNA2D1 UG0898H09 ADAMTS20 LOC101929604 PARK2 TCP11L1 FAM154B VIM-AS1 AC093375.1 LOC101928069 LOC101928704 SLC7A14 OPCML NEFM THSD4 HS3ST5 KDM1B TTLL6 AK5 GPR179 SLC18A1 FEV FAM135B TCF24 TCEA3 RAPGEF4 RP5-1033H22.2 LOC102724851 RCBTB1 FAM178A CLASP2 LOC101927331 LPPR1 GALNT13 DOK6 MMRN1 CLSTN2 LOC101060391 GABBR2 RAPGEF5 KCNN3 AFF2 LMCD1-AS1 SNORD44 SYNDIG1L ST18 WASF3 MYO9A SEZ6L PKI55 DCX RGS7 DPP10 PLXNC1 TARBP1 FHOD3 KCNA3 PIEZO2 KAT6B LPAR1 CDKL5 TMOD2 HMP19 ZNF658B TRNY TMED8 MAP3K15 CHODL ZNF483 PRPH2 CYMP RAB39A PCNX LINC01021 SEMA5A C11ORF87 ARSJ C21ORF88 LOC101927279 RP11-242D8.1 LOC728755 LOC102724733 ANGPTL7 ATXN7 LOC102724230 AC009501.4 LOC151760 GPR158 CTNNA3 ANKS1B NBEAL1 LOC102724873 500 genes up-regulated by SARS-CoV-2 in human liver organoids from GSE151803 SARS-CoV-2 infection of human liver organoids Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/tB8qnUqrf BIRC3 NIN CCL2 UBD SPINK1 NMI DDX21 IFITM3 CWC27 GTF2F2 NCL NFKB1 SPTBN5 NCKAP5 STAT1 IFITM2 TMEM176A B2M NPM1 TRIM31 CXCL2 GGH MX1 NSUN3 PGM2 WDR89 PITPNC1 AFAP1L1 FKBPL ZFAND1 MCL1 CHEK2 ENO1 CXCL1 CXCL6 TSHZ2 PIGR RPL41 YAP1 ELF3 FOPNL H3F3AP4 SNORD17 OSMR RPS3A MARCKS STEAP4 RPS25 DLGAP1-AS1 LCN2 WDR78 TAGLN2 TNFAIP2 APOL1 SLC15A3 APOL2 HLA-E SDC4 EAF2 RBBP8 GALNT2 ANXA5 UACA OSTC FAM89A LDHA TPI1 ARNTL2 IGFBP3 TRAM1 KLF10 MMP3 NUCB2 HIF1A BCL3 CFB CCL20 DBF4 LPXN CTSS SYT12 LACC1 IFIT3 OAS2 C3 CXCL3 PSMB8 CD274 APOL6 KYNU IL1RN CCNE2 IFI16 IFIH1 PLEKHA4 SOCS3 TIFA PARP9 PARP12 TMEM171 CASP4 IFI35 PARP14 PPA1 UBE2L6 TLR3 GCKR WARS IQCH PSME1 PTGES3 IER3 YBX3 BMP6 MAP1LC3B IRF1 PSMB10 RASGRP3 TGM2 ICAM1 DTX3L NFKBIA SYF2 KLHL5 MRFAP1 PSMB9 GBP3 SEMA3C WBP5 LITAF TUBB TMEM176B CETN2 C6ORF57 C10ORF10 IFI30 BMS1 PIM3 SLC39A1 DSTN NAB1 LRG1 HLA-DMA RBM7 SRSF3 PDCL3 SUB1 SET SLC38A2 RBM8A C1ORF54 DEK CBX3 ZC3H12A LCA5L ZNF597 ACTRT3 TRIM22 TNFAIP3 ZNF267 S100A3 FUS STC1 MIR210HG IL10RB-AS1 NEURL3 BHLHE40 NFKBIZ CDC42EP3 ANP32A SNRPG SUPT16H ASNSD1 TMEM33 LYPD1 DDX18 TIPIN TPRKB SPRED3 PPP1R18 PCNA MRPS23 ZW10 PTMA SNX7 SSB CAP1 STEAP1 SSR2 RUVBL1 USP1 NUP107 DCTN6 LEO1 MRPL18 ERO1LB ODC1 EFNA1 GSPT2 C15ORF48 KDSR RND1 IL1R1 NEDD1 NNMT TAP2 RPAP2 VRK2 SLFN5 CASP1 IL15RA ETV6 TRIM21 TRIM69 MAP3K8 RIPK2 IL27RA IRAK2 LRRC42 OTUD6B TAAR3 TMA16 IL32 RECQL SLC20A1 CFI DDX60 ARL13B LPGAT1 SNRPA1 TAF1A SP100 RARRES3 BCL10 IFIT5 RBMX UFM1 CASP7 PJA1 IGFBP1 CCDC91 GFPT1 ANKRD12 CEP290 TGS1 GPR128 ETS2 PLK2 RBM34 BTN3A3 BAZ1A CX3CL1 ERAP2 SP140L ACHE BTN3A1 PLSCR4 PANX1 CHSY1 TRIM38 TRIB2 BPGM BLZF1 BTN3A2 IL7 C8ORF4 RNF149 RAB8B SERPINA1 RPS6 RNF6 LPAR6 GNE SERPINB8 NEK6 SRSF12 BACH1 STK17A TNFRSF10D PLSCR1 FGF2 NCOA7 RARRES1 IFNGR1 IFNAR2 IKBKE SYS1 THUMPD1 APOBEC3F TNIP1 RGS19 CRP TNFSF11 PARP1 XBP1 NFKB2 FAF2 TSN APMAP TNFAIP8 ZIK1 FKBP14 SQRDL PWP1 UBA6 APIP MCFD2 ARPC1A CMPK1 CLNS1A CDC42SE1 ABHD5 SLC35C1 KTN1 NSRP1 MSH6 CEP63 DNTTIP2 GNL3 MTA3 SNAPC1 SPATS2 HSPB11 MRPL33 TMCC1 MSL3P1 ALPK1 SLC9B2 TMEM154 UTP6 STX6 SPCS3 HILPDA CPM ZNF674 OSTM1 SENP1 E2F3 RAB27A SRPK1 MTAP PGM3 IFT57 IL6ST ZFAS1 ARSB PROX1 TLR5 COQ10B NRAS TFPI MFN1 GOLPH3L ZNF136 GIN1 MTRR IL13RA1 DNAH5 MTHFD1L PSMG1 SUCO RANBP1 PLA2G2A TGIF1 MCM3 ERN1 NEIL2 UTP3 ZCCHC10 PRPF4 TMEM138 MRTO4 CASP10 SDCBP TXNDC9 OGFRL1 PLA2G4E ALKBH8 NANS BRCC3 IKBIP THAP1 TXNL4B SRPRB GTPBP4 KIF21B CXORF38 ARHGEF19 CDRT1 LYPLAL1 CNTNAP3 CCDC50 MSANTD3 RSL24D1 CLDN12 NABP1 HSPA13 ZNF146 SENP2 RASA2 CCDC82 CHML C2CD4A FAM86B1 GOPC ZNF222 EEF1E1 LSM3 ZSCAN16-AS1 PHKA1 DNAH14 HIGD1A HNRNPR VWA5A C1RL MED21 PNRC2 DNAJC1 BTBD10 CCP110 ENSA AP4B1 BRWD3 NIFK PDCD2 RAB12 BLM APOLD1 FAM46C SMIM11 TCEB3 UPF3B FTO ERO1L ULK4 SSR1 ZDHHC2 ATHL1 DESI2 RFXAP CPNE8 IL8 SLMO1 SBDSP1 FAAH2 CCDC59 ZNF559 NUPL1 DIS3 NR2C1 TUBD1 POC5 TTC21A MIPEPP3 LOC101927838 UTP11L LOC101928927 LOC101928527 SLC9B1 CBWD5 FAM204A LUCAT1 RP6-206I17.2 TMEM206 ZNF582 C15ORF57 ZNF438 AC093391.2 SPATA6L LOC101927060 LOC101926907 ODF2L N6AMT1 GS1-251I9.4 LOC102723726 LOC102724791 LOC101929761 UBXN10 DNAJC24 TTC5 TMF1 TMEM217 TRIT1 LOC158960 S100PBP TSACC MINA RABL5 LOC101929475 SNORD56 DIEXF SNORA8 PCDP1 LINC00649 CEP41 MSH3 CWF19L1 ZNF833P SHC2 MKLN1-AS 500 genes down-regulated by SARS-CoV-2 in human liver organoids from GSE151803 SARS-CoV-2 infection of human liver organoids Source paper: not listed BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/tB8qnUqrf TMEM82 GLYCTK PBLD TMEM37 PRAP1 FBXW5 DGAT1 C1ORF115 SLC27A2 OTC SCAP UGT2A3 ESRRA UPF1 ZZEF1 TMUB1 ARRB2 CYP2J2 YIF1A GUCA2B KHK SDCBP2 CRYL1 ZBTB7B SIGMAR1 TTN ACAA1 SLC27A4 SPTBN2 VARS FMNL1 ABCG2 MGAT4B SLC5A9 SIRT5 POR PEPD DHRS11 WFS1 MEP1A AKR7A3 EPHX2 CAT FBP1 ACADS REEP6 MXRA8 DHTKD1 SFXN5 RDH14 ADHFE1 TMED4 POLRMT ACBD4 FAHD1 AQP11 METTL7A BCL2 SDC1 UQCR10 CCDC7 C1ORF21 FGFR2 KIAA1324 KLHDC9 CHST9 PIEZO1 MAPK8IP3 UQCRC1 DPP7 HS1BP3 HDAC6 CLUH SULT1A1 VSIG10L CEBPA FRRS1 NDUFS7 TMEM38A ITGA7 DERA SLC39A11 NUDT16 SDHD GSTO1 FAM20C OPLAH CBR1 GRHPR TBC1D2 LTBP4 MIB2 COL18A1 ABCC6 SLC2A8 PLEKHH3 PPP1R16A CARD14 SLC26A1 SLC2A4RG MEF2C RHOU FRAT1 HERC2 KRT13 SORL1 ZNF628 KMT2B RAB11FIP3 ARHGAP35 RXRA FBRS SCAF1 ULK1 GLTSCR1 PRR12 PTPRCAP HIST1H2AE CYP1A1 PGAM2 HMGCS2 C1ORF56 SLC3A1 CNGA1 DDC PEBP1 TMCC3 SH2B1 ALDH1A1 ATP5D NSMF EVA1B MXD4 TNS3 SELENBP1 TPRG1L CD36 NUDT16L1 VCL OAT SCAND1 MARC2 SLC25A25 CLDN16 AKR1E2 SULT1E1 RUNDC3B NAPSA SNCG PAH ANO8 SORBS3 SKI CYP4F3 IRS2 FAM161B MRPL34 ATP6V0E2 DCXR CPLX1 POLR2E BTD SRPK3 VPS51 HYAL1 INSIG1 GAS2L1 PCNXL3 TMEM169 MLXIPL APBA3 LMTK3 NAGPA LAT2 NRAP ASB13 DGAT2 ACTN4 ARRDC3-AS1 HIST1H3H ABAT LRRC45 PDZK1 NOTCH2NL SELO BOP1 TRPV1 WEE1 PANK1 COX5B UQCR11 HEXIM2 MAST3 LOC728743 SLC25A42 BMF DOK7 PDLIM2 BCAR3 SEC14L2 NR0B2 SLC17A9 RDH12 LPPR2 GPRC5D FCHSD1 MYO16 ACY3 RNF125 PRKCD PLA2G6 COQ6 RANGRF NADK CLPP HAGH ZNF44 NUDT8 FBXO27 CLCN7 ABHD12 TBC1D17 SLC25A10 MPST STBD1 LOC202181 C19ORF24 IRF2BP1 NARFL RAC3 ALDOC SPNS1 COMTD1 SGK2 CEMP1 ADCK5 PINK1 ADI1 DGCR6L APC2 LRP3 GLI4 GNPTG ZNF219 SMPD1 AMDHD2 FDXR NCOR2 PRADC1 CRTC1 MBD3 KLC4 CYC1 PQLC1 MFN2 OSBPL5 SLC9A1 PLXNA2 SGSM2 PDGFA RNF123 MFSD7 PPARA G6PC CMBL MEGF9 HECTD4 DLEC1 CYP3A5 RAB40C FOXP4 SCARF1 RAB26 UBR4 RPS6KB2 EMC6 CTNS ZNF383 SLC46A1 ABCA2 IL17RC NR1H3 CPT2 UGT2B10 FMO5 AKR7L HGD GJB1 ACSS2 LCAT CRAT KCNIP3 GLS2 FZR1 PIN1 TP53TG1 ENDOG ZNF142 ECHS1 JOSD2 NIPSNAP1 MED26 TIAM2 OSBPL7 PXMP2 MRPL41 PCYT2 SLC22A18AS SLC25A1 DECR2 GAMT VPS26B IZUMO4 ESPN SDCBP2-AS1 SLC35D1 PDK2 HCFC1 CASKIN2 PDF NR2F6 C8ORF82 ALKBH7 ECI1 RITA1 NDUFS8 MAP4K2 UCKL1 RFNG SNTA1 ECH1 DCAF11 ZNF592 SETD1A PHYH ZNF815P AHDC1 PRKAB2 PAOX WBP1 KMT2D ZHX3 DND1 PALM3 ACOX2 GCDH MLYCD CCDC107 PCCB NADK2 DGKD PKN1 CLASRP FOXJ3 FBXL15 RDH5 ANKRD29 SEMA6C UBALD1 SH2B2 DMWD NECAB3 TMEM220 FADS6 GPR153 MCF2L-AS1 ZDHHC8 ARHGAP39 FAXDC2 ARMC5 FAM63B ACSF3 DOLK UBAC1 MYPOP NELFA PEX14 NAT6 E4F1 TACO1 LYRM7 FLYWCH1 ZGPAT FAM195A ZNF775 SH3GL1 ZNF358 KIAA0195 NUDT22 LYNX1 C15ORF37 SPSB2 LOC92249 POLR2M LINC00174 AKAP6 HAGHL TIGD5 CHERP KLHL25 FAM69B PIEZO2 LOC101927279 SLC22A17 LOC102724562 NAPRT1 LOC730101 LINC01138 ZNF234 NPHP3-ACAD11 C17ORF59 MRPL38 SCARNA12 RTKN TMEM175 LOC101928303 ACRBP TCEANC PEX11G AC074286.1 ENDOV QTRT1 C3ORF18 ZNHIT2 TOR2A CCNB3 FBXO44 FAM86HP CECR5 SLC25A34 TMEM220-AS1 THAP7-AS1 LOC102723775 AMIGO1 SNORA33 GLTPD1 OGFOD2 LBX2-AS1 LOC646021 ZBED3 SNORD45C RNF208 CSRP2BP C12ORF73 PQLC2 JHDM1D-AS1 MEX3D C1ORF220 BMS1P2 MMRN2 C19ORF73 CEBPA-AS1 NKAPL KCNMB3 ZNF512B GNB1L AQP7 OXER1 MON1A SLC43A1 C21ORF2 ABHD15 SLC45A1 ZNF276 MAMDC4 AGAP11 LOC101928595 DAGLA OXNAD1 NEIL1 GALT MCMDC2 EVI5L TMEM8B LOC101927044 KLHL17 PRDM11 LOC102723845 LOC102723779 POLN CCBL1 DAK RAB17 UBE2Q2P1 LOC100506639 FAM3A ZNF768 PP13 LIME1 SNORD32A LOC100288846 DOCK9-AS2 AC011747.7 PCED1A PCSK4 RP4-756H11.3 LPIN3 LOC101928433 RPP25L TSSK4 500 genes up-regulated by SARS-CoV-2 in mouse lung tissue from GSE150847 SARS-CoV-2 infection of mouse lung tissue Source paper: https://pubmed.ncbi.nlm.nih.gov/32643603/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/SxikiqqCR GLA SYVN1 CCL2 ATP6AP1 ZC3H7A DDX58 CXCL10 ESRRA ZZEF1 ATF6 PVR COL4A1 DLEU2 IFNG SERPINE1 FN1 B2M MYCBP2 TMEM173 MOV10 STOM ISG15 CD4 MX1 4932438A13RIK ITGA2 TNFSF10 MCTP2 CD180 TET2 MALAT1 ISG20 PLA2G7 ATP10A TMEM184B ARID5A PDIA6 ADCY7 PARP10 LGALS3BP THBS1 SLC3A2 TOR3A LRP10 TGFBI SH3BP2 BST2 ITGA5 GRN SYNGR2 NCSTN P2RX4 SDC4 C3AR1 TMEM106A IFI44 MSR1 GPNMB SCIMP C2 BATF2 CERS6 CCR9 B4GALT5 NOTCH1 MPEG1 AGRN SLC7A5 EPPK1 LAMA5 SLC7A1 DDHD1 ABCA7 NOTCH2 HELZ2 PLXNB2 SBNO2 PTPN22 RSAD2 OAS3 CD69 IDO1 IL10RA IRF7 CFB RGS1 ATP8B4 ZBP1 APOD SLAMF7 NLRC5 IL18BP GBP5 TAP1 PLD4 NCAPD2 SLC29A3 GZMA IFIT1 ITGB7 CCR5 PTPRC LAG3 IFIT3 TLR7 SLC7A8 OAS2 CD86 SIGLEC1 XAF1 CH25H CD274 DHX58 GPR141 IL1RN USP18 CMPK2 IFIT2 EVI2A ALAS2 DHFR PLAC8 HERC6 IFIH1 MLKL LGMN STAT2 SFTPB PML VCAN TCIRG1 TINAGL1 ADAR PARP12 SAMD9L XDH DAXX HPSE CASP4 NOD2 LIPG RNF213 PARP14 TRAFD1 GPR35 PARP11 UBE2L6 ANGPTL4 TLR3 HAP1 UBA7 IRF2 LY6E PLVAP ICAM1 DTX3L LAMP2 LYVE1 TAPBP CCNL1 IL2RG THEMIS2 ELOVL1 CCNL2 NXF1 ART3 TNFAIP3 TLR9 NAPSA ROBO4 CSRNP1 TAF1D ZNFX1 PFKFB3 VMP1 MALT1 SCARNA2 NEAT1 HMGCR ITPRIP TAP2 P2RY14 PRF1 IL15RA ZCCHC2 GCA CD40 SLC28A2 RNF31 SELL ASCC3 TDRD7 AREL1 ACAP1 CXCL11 FNBP4 FIRRE DDX60 SMG1 SP100 MX2 NAA25 SRRM2 CEACAM1 RHBDF2 WHAMM GTPBP2 CD53 GZMB KLRK1 XIST EVI2B SEMA7A AIM2 MCAM SDC3 NR1D1 C4B ANGPT2 CCL12 BDKRB2 CCL7 CD93 TANK DOT1L TNFRSF1B GBA OAS1B KCNJ15 CLCN7 TMEM209 ATP7A TEP1 ATP13A1 ZFYVE26 ALPK1 TPP1 JAK3 VPS13D OASL1 PTPRJ KLK1 MTHFR ARHGEF37 INHBB RNF225 MCOLN1 SCARF1 UBR4 SMCR8 SETDB2 LY6C1 SLCO3A1 SLC15A4 SLC23A2 CCN1 DOP1B DOCK2 NRROS SUSD6 HBB-BS H2-T23 H2-D1 H2-K1 ARHGAP17 FNDC3A TMEM131 MFAP3 TMEM67 TTC17 SZT2 NOCT SCARNA13 DCLRE1C KMT2D RESF1 LY6C2 IGTP H2-T22 GM4070 SERPINA3F H2-Q4 GM4951 H2-Q7 SLFN4 APOL9A LY6A TRIM30A IFIT3B IFI204 GVIN1 H2-Q6 OASL2 APOL9B SLFN2 MS4A6C IFI211 HBA-A2 MNDAL GBP8 FCGR1 MS4A6B PIRB MS4A4C LILR4B IFI205 MS4A6D NT5C3 GM49339 IFI209 PHF11D PHF11B TRIM30D HBA-A1 IFIT1BL1 H2-T24 SLFN8 9930111J21RIK1 9930111J21RIK2 IFI206 IFI203 H2-Q5 PSME2B H2-M3 IFI213 SLC9A8 P2RX7 SLC12A4 TSIX TPCN2 IFITM6 IFI202B GM11127 POM121 H2-K2 KCNA3 A930037H05RIK GM45221 SIRPB1A GM26397 AW011738 GM8989 GM24357 GM45193 DENND1A GM25360 GM37082 CD300LD5 GM10552 A430027C01RIK GM9574 C530050E15RIK GM28967 GM38372 GM26857 OLFR1396 G530012D18RIK F630028O10RIK GM47166 GM42664 F830112A20RIK GM27505 IFI214 CLEC4A1 ARHGAP27OS3 GM20489 LILRB4A F830016B08RIK GM12185 GM24119 GM18301 LY6I GM42549 H2-T-PS GBP11 IFI208 GM26981 GM6545 GM23262 9430034N14RIK GDAP10 GM8995 SCARNA10 GM25395 AC119228.1 GM22442 TMEM181B-PS TAZ SARS-COV-2 PHF11C IFI203-PS FAM196B BE692007 GM38377 GM37084 BC023105 GM37472 RETNLA AC174471.1 GM47260 9130208D14RIK GM37488 GM27694 GM20661 GM25939 NEMP2 IFI207 H2-Q10 GM8810 1810026B05RIK GM7030 TLR13 GM5960 MS4A4B A130071D04RIK GM28006 EVI2 GM18853 GM44283 CHRNB2 SIRPB1C GM14636 C130089K02RIK GM47087 GM49730 GM10499 GM23849 SLFN10-PS ZFP276 GM36931 IFIT1BL2 GM11425 GM27240 GM26316 GM26035 GM38020 CD300LD GM47657 GM44668 GM22988 GM24497 APOL10B GM37033 GM18852 GM43858 GM44292 GM31172 GM43010 GM27927 GM42659 GM26621 GM37589 GM43633 GM22009 GM45555 ZFP142 GM37376 SYT15 GM5970 GM38050 GM45223 GM20559 GM15821 GM26992 H2-Q2 GM17300 KLRA2 LNCPINT GM26716 GM37474 G530011O06RIK PHF11A GM15929 GM5431 CLEC4A3 GM24950 5830428M24RIK GM23119 MS4A14 A630001G21RIK GM40645 GM1966 GM6377 GM38357 I830077J02RIK GM15056 GM29233 GM43197 ZUP1 GM19412 TRIM34B AC123927.3 GM37420 GM37238 GM20547 GM43462 GM38236 GM16185 CT025731.2 ZFP579 500 genes down-regulated by SARS-CoV-2 in mouse lung tissue from GSE150847 SARS-CoV-2 infection of mouse lung tissue Source paper: https://pubmed.ncbi.nlm.nih.gov/32643603/ BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/SxikiqqCR TBCA NAALADL1 SIS MAP1LC3A RPL36 ENPP3 MYO1A MYO15B VIL1 PF4 ETV1 FRMPD4 ERG TUBA1A CLEC2H CLCA4B APOA4 DMBT1 RDX CHP2 CYB5R3 F2 CRYBB3 ALDOB KRT20 CXCL2 TLN2 MUC13 FCGBP CDHR2 SPTBN1 NAP1L1 GLO1 CREBL2 TLCD1 DDAH2 RPS17 RPL37A TSHZ2 NT5DC2 LMNTD1 UQCR10 REPS2 RAB40B CGNL1 MT-RNR1 RPS15A PPL HIST2H2AC RHOBTB3 PNRC1 MT-RNR2 SLC25A4 ADH7 PTGFR WDR38 NDRG2 FMO2 RPL31 SLCO2B1 ALOX5 VASH1 SLITRK4 CCNB2 ME1 JPH4 CCNB1 TTK PAPSS1 SLC22A16 KCNMA1 GSTM2 GSTM1 G0S2 CAMK2N1 CDHR1 ABCC9 DSCAM CKS1B TRAK2 COL17A1 TFAP2A EVPL RHOD PYGO1 BNC2 FGF7 EDNRB DLX2 FGF1 STMN2 FOXL1 DACT1 GABARAPL1 CNGB1 PAX6 GLIS1 IQGAP3 HIST1H3D CX3CR1 B3GALT5 KCNA6 DPF1 NTRK2 GRIA1 STON1 HMGCS2 CPNE5 JPH3 LYPD8 GDF10 PCOLCE2 NETO1 LRAT INMT ACTC1 RNF7 CRYAB BAG1 FMO1 PEBP1 TPPP3 HPGD RPS23 RPLP0 CYB5A CRIP1 DCN EEF1B2 RPS21 DPT TAGLN PRX PPP1R14A GSTA3 EID1 SH3PXD2A KIF26B GLRX5 IGFBP5 CNTN1 OIT3 DLK1 COL9A2 NTRK3 CDK5R2 SCARA5 ALX4 GC ATP4A PRR16 PCDHA9 TET1 HMGN5 PPFIA3 ANO7 CRYZ LSM2 MGLL HTATSF1 NEK7 HIST1H3G KHDRBS3 CNN1 MAP1B MYH7B PRRX2 CLEC3B STRA8 ATP10B WT1 CCDC105 GCAT CDC42BPG MEDAG LBX1 CDKN2C GRIK4 CLGN TMEM126B BPIFB4 MROH2A DUSP9 GABRA3 TMEFF2 ABAT FAM149A SCOC TRANK1 MYL9 RPL36A SKIDA1 ADAMTS5 IGIP GAS1 SMOC2 INSM2 RCAN2 UNC80 DPYSL3 ACTG2 SCRT2 KLK6 MMP24 ABCA12 TMEM72 PYGM POU4F2 PCDHA8 TGFB3 COL25A1 MASP1 GTF2H5 THAP12 SIM2 FAIM2 NEDD4 LARS2 GSTK1 NXNL2 COX6B2 EPHA10 AHNAK KRT9 HOXC8 SLC12A8 SMIM13 KCNC4 PINK1 PCDHA11 PCDHAC1 SYNM MPC1 NECAB2 PPP1R14B KCTD10 ABLIM3 TTL TRIM9 APOB GAS7 NPAS2 MAGI2 WWTR1 STRC LIN7C PCDH15 DCLK1 AMOT PTP4A3 YAF2 NDUFA4L2 APOA1 KCNK10 FMO5 ACSM5 CYGB RGS6 ALDH1A2 SOX4 NDN RPS4X CAVIN2 HIST2H2AA2 RPL10-PS3 DBNDD2 IMP3 DUT CSPG5 LGALSL MTSS1L PARD6G KLHL13 PPP1R3C VGLL3 NTN4 BICC1 PHACTR2 ALOXE3 PALLD SSPN RTL8B KSR2 APBB1 KIF1C OXCT1 RELN AKR1C14 HIST1H3F ADH1 CCL21A HIST1H2AF RASSF8 DPYSL5 SHC4 SEMA6C OSR1 VWA5B2 PGM5 RBP1 MT-TV MTURN CLYBL NHLRC2 MT-TL2 FAM213B MT-TI GM15772 BMYC GPR27 PKIA SH3GL3 GNG7 FAM171A2 CDKL2 SPEF1 WASF3 SEZ6L DPP10 TMOD2 SHC2 ABCG4 GM27021 VMN2R24 PRSS56 GM10720 VMN1R203 GM26461 RPL35A-PS3 MEI1 OLFR1116 GM47295 GM43166 GM24187 JCAD 5033428I22RIK GM10260 GM19165 CRHR1 GM29237 AW551984 GAP43 GM48529 GM13425 GM26861 1810012K08RIK GM37151 SLC12A5 SAMD4 GM44669 RN7S6 9530053A07RIK HIST1H2BR SNORD100 AW822073 GM7298 GM44350 GM11168 MT-TQ CYB5D1 GPC6 GM33432 GID4 RN7S2 GM47299 ANO4 GM21149 GM12735 CHD5 ARHGAP20 PCDHA1 AAED1 OLFR1382 GM45102 GM49450 AY702103 GM26883 DEFA23 CD209F 5430419D17RIK TMEM59L COL6A5 GM28439 OLFR1418 GM34354 KCNA2 BHLHE23 AI593442 GM47305 LVRN GM29100 REG3B ACSL6 ITGBL1 GM21541 GM48008 RGS7BP GM10561 GM47287 OLFR648 GM10076 SPRR2A1 USP29 OLFR763 HTRA3 PNMAL2 GM11400 OLFR427 PCDHA5 SERF1 GM10282 VMN1R85 A930004D18RIK GM47311 C130074G19RIK MROH5 RPL15-PS3 HOXA11OS GM7611 RN7S1 KLF14 LHX3 A230005M16RIK ARX DEFA20 GM26714 SPRR2A2 DEFA24 GM49372 FBXO41 KLHL1 DEFA17 GM9573 BC029722 PCDHA3 ACSS3 SLC17A7 BEND6 EPM2A VMN1R68 DISP3 MYO1H A530084C06RIK CLIP3 DEFA21 1700020I14RIK CYP2C52-PS GM9866 PCDHAC2 GM29895 GM45633 GM7849 ZFP982 ZFP651 CHRM1 RPS2-PS10 GM49794 2810032G03RIK HOXD1 GM26619 PABPC1L2B-PS OLFR1351 FOXN4 GM20659 9330102E08RIK S100A1 SLC6A21 DUSP3 GM47304 GM12191 GRM2 UBE2QL1 XKR7 USP46 HOXA11 1700084F23RIK SULT5A1 GM49089 RPRML SIM1 SNORD35B SPTBN4 RNCR4 ALDH3B3 GM6999 D430041D05RIK DEFA36 LHFPL5 TCTEX1D1 NPCD GM41409 GM13093 KCNS1 DLGAP3 GM17535 GM26793 TCHH GM26735 RFTN2 GPR45 Top 150 positive hits from GSE154783: SARS-CoV-2 CRISPR screen in Vero-E6 cells A SARS-CoV-2 CRISPR screen was performed in Vero-E6 cells to identify host genes that regulate SARS-CoV-2 infection. Reported genes were mapped to human genes in Entrez format. Cai WL et al. (2020) Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection [RNA-seq]. Gene Expression Omnibus (GEO), accession GSE154783. MYH9 F2RL1 PIGS MYO1D IGSF3 PMEPA1 SLC46A3 HSP90AA1 HOXA9 TP53 STAT1 EPB41L4A SMO LIFR PCLO TGFB2 EXT1 SYTL2 COBL COBLL1 KIF21A SLC2A1 SAMD12 ABLIM1 LCN2 NEDD4L CD24 PROS1 NREP ANO5 ADAMTS2 GLDC EFNA5 DSP FAM84B JUP PLCD3 KRT80 CLU CACNA1H SORL1 LFNG SLC29A3 BTG2 ELOVL5 ID3 NPNT PDE5A MYH10 BNIP3 ARRDC3 EIF4E3 PHLDB2 NRP1 FAM102B NLGN1 ESRRG FILIP1L KIAA0408 SEZ6L2 NRBP1 PHLDA3 SLC44A3 VAV3 CADPS2 TNFRSF19 MAP2 NEURL1B CDH6 SMAD9 SIK1 TSPAN33 PELI2 CRISPLD2 GLG1 PLK2 FAS TRIB2 ADD3 LMCD1 FRY RCAN2 SDC3 DSC2 SLC26A7 ADAMTS9 TRPM3 TGFB3 HSPA1B TIMP3 DAB1 EPHA4 TSPAN14 KIF13A PLCXD2 STOX2 DTX4 ADD1 KDM3A NCOA2 SHROOM3 EPB41L4B CNTNAP2 CLMN FBXO32 RNF130 UBR4 SCN9A ABCA5 NCOA1 CCNG1 DSE PLCG2 DCBLD2 BCAM F11R PEG10 DPF2 NRCAM SHB COL8A1 TENM3 SULF2 CPE KLHL13 ZNF608 FAM171B BICC1 KREMEN1 KMT2E SOS2 CCDC69 EHD3 DGKA CAMK2B SMC6 LRP4 ATP2B4 RAB11FIP4 RNF38 CCDC64 TMOD2 CDS1 RNF157 RIMKLA SH3RF3 GNAO1 RIMS4 ICK SHROOM2 Top 150 negative hits from GSE154783: SARS-CoV-2 CRISPR screen in Vero-E6 cells A SARS-CoV-2 CRISPR screen was performed in Vero-E6 cells to identify host genes that regulate SARS-CoV-2 infection. Reported genes were mapped to human genes in Entrez format. Cai WL et al. (2020) Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection [RNA-seq]. Gene Expression Omnibus (GEO), accession GSE154783. UHRF1 CTSL LOX CDH17 PCK2 IL1A MME ACE2 NEDD9 CENPF COL4A3 ETV4 GGT1 TUBA4A NCKAP5 TSPAN8 FBN1 CLDN10 ARHGAP18 PLEKHO1 CGNL1 SLC4A4 UPK1B SCEL FMN1 GPRC5A S100A2 LEPROT ABCC3 AREG MGST1 LGALS1 SPRY2 LGALS3 EPS8 ARHGAP23 ABCB1 ARL4C CAMK2N1 RUNX2 ABCC4 MMP1 ABCC2 AGRN SLC38A1 EREG PTH1R CIDEC PSAT1 TMEM52B LGMN SLC7A11 INHBA PLAU NETO1 TSC22D1 EHD4 TNS1 ST5 JUNB SEMA3C FABP5 VEGFA S100A4 MAT2A SERPINE2 MYLK IVNS1ABP SLC12A1 SPOCK3 OLFM4 IL11 TM4SF4 MMP10 NQO1 DNER CORO1C GNAI1 RPS6KA3 AKR1B1 SEC11C SGMS2 RSPO3 VGF COL7A1 PAQR5 ASNS GCHFR SLC1A4 SLC20A1 NHS ST3GAL1 EMP1 TRIB1 LAMA3 STK32A TBX18 APBB1IP SH3TC2 NCF2 OTUB2 SPP1 SLC39A8 ANKH MDGA1 PODXL BTBD9 SLC38A5 ABLIM3 PC ATP6V0A4 SLC17A1 SLC7A13 WWTR1 RTL1 CTH SUCO HTR2A SERPINF2 LAMA4 SLC23A2 UGCG TACC1 ENO3 FLNB GPC4 RUSC2 LRRN3 CSGALNACT1 MTSS1L ANKRD50 STK17B VGLL3 CCDC50 COL22A1 MACROD2 SLC35G1 GAB1 NHSL1 ZMYND8 GPR153 MYOM3 GABRA2 PKIA SLC35B4 JADE1 TENM4 NAT16 SH3D21 GABRB1 27 Positive hits from CRISPR screen from Hoffmann et al. (PMID 32935098) in Huh-7.5 cells at 33 deg C To identify host factors required for infection by SARS-CoV-2 and seasonal coronaviruses, Hoffmann et al. designed a focused high-coverage CRISPR-Cas9 library targeting 332 members of a recently published SARS-CoV-2 protein interactome. They screened SARS-CoV-2 & 3 other coronaviruses at 2 temperatures. Hoffman et al. (2020) Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors. https://www.biorxiv.org/content/10.1101/2020.09.11.291716v1 SRP19 CSNK2B EMC1 DDX10 COMT MOGS SCAP NPC2 NOL10 GPAA1 SRP54 PIGO PSMD4 GIGYF2 EIF4E2 CUL2 MEPCE SRP72 INTS4 PABPC1 VPS39 VPS11 HS2ST1 RAB10 TPT1 ZNF131 PCF11 26 Negative hits from CRISPR screen from Hoffmann et al. (PMID 32935098) in Huh-7.5 cells at 33 deg C To identify host factors required for infection by SARS-CoV-2 and seasonal coronaviruses, Hoffmann et al. designed a focused high-coverage CRISPR-Cas9 library targeting 332 members of a recently published SARS-CoV-2 protein interactome. They screened SARS-CoV-2 & 3 other coronaviruses at 2 temperatures. Hoffman et al. (2020) Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors. https://www.biorxiv.org/content/10.1101/2020.09.11.291716v1 TARS2 TBCA PRIM2 DNAJC11 MIB1 ACAD9 CWC27 SLC30A9 MRPS2 SEPSECS GRPEL1 PITRM1 MRPS27 BRD2 BCS1L FBL MRPS25 NARS2 NDUFB9 NDUFAF1 DCAF7 DNAJC19 CHMP2A TOMM70 SLC35B1 SAFE_26 21 Positive hits from CRISPR screen from Hoffmann et al. (PMID 32935098) in Huh-7.5 cells at 37 deg C To identify host factors required for infection by SARS-CoV-2 and seasonal coronaviruses, Hoffmann et al. designed a focused high-coverage CRISPR-Cas9 library targeting 332 members of a recently published SARS-CoV-2 protein interactome. They screened SARS-CoV-2 & 3 other coronaviruses at 2 temperatures. Hoffman et al. (2020) Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors. Data from Supplementary Table S1E. https://www.biorxiv.org/content/10.1101/2020.09.11.291716v1 CSNK2B EMC1 RAB2A CSDE1 SCAP RHOA LARP7 ALG5 RAB14 PSMD4 EIF4E2 FAM98A CUL2 PRIM1 ALG8 MEPCE HS2ST1 DCAF7 RAB10 ANAPC5 SAFE_27 28 Negative hits from CRISPR screen from Hoffmann et al. (PMID 32935098) in Huh-7.5 cells at 37 deg C To identify host factors required for infection by SARS-CoV-2 and seasonal coronaviruses, Hoffmann et al. designed a focused high-coverage CRISPR-Cas9 library targeting 332 members of a recently published SARS-CoV-2 protein interactome. They screened SARS-CoV-2 & 3 other coronaviruses at 2 temperatures. Hoffman et al. (2020) Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors. Data from Supplementary Table S1E. https://www.biorxiv.org/content/10.1101/2020.09.11.291716v1 DDX10 HECTD1 WASHC4 MIB1 ACAD9 AP3B1 CWC27 RBX1 NDUFAF2 SLC30A9 PLEKHF2 ECSIT MRPS2 MRPS5 PITRM1 MRPS27 FBL NUTF2 MRPS25 UBAP2L NDUFB9 RAB7A VPS39 ELOC CHMP2A DPH5 TOMM70 TPT1 Daniloski et al. Cell CRISPR screen to positive hits Identification of required host factors for SARS-CoV-2 infection in human cells TMEM82 ERMP1 ATP6AP1 CTSL UBC ATP6V1A ACE2 ATP6AP2 TOR1AIP1 ACSL3 MRPS27 SFN RAB7A VPS11 GFER ATP6V1B2 SF1 ATP6V1G1 C1ORF63 MBD6 TMED9 SRD5A1 MRPL37 KCTD3 DEPDC1B LGALS1 SHMT1 S1PR5 NELL1 SLC9A3R2 GOLPH3 AKT1S1 SGOL1 POLE2 MDFI SOCS1 WBSCR17 THBD ATP6V0C ARPC3 ARPC2 C11ORF96 SDPR SAP30L ATP6V0B VPS35 VPS26A ODF3 FAM166B NAT8 DPM3 ATP6V1E1 ATP6V1C1 ATP6V0D1 SLC39A10 MRPS30 NARS HIST1H3G KIAA1683 SRXN1 NRAP C3ORF33 CLDN14 CCDC77 CEP104 KIAA1033 GNB2L1 ARPC4 ACTR2 ACTR3 CENPV WFDC9 PLXNB3 ACP5 CATSPERB RNF125 VPS29 TBXAS1 TNKS SPEN STX7 PPID NECAP2 TMEM199 PIK3C3 UVRAG FBXO27 ATP6V1H BECN1 CCDC115 COMMD3 CCZ1B IL37 BOC SMARCB1 WDR81 RPS19BP1 KLC4 LOC388813 HNRNPC CCDC71L AGAP3 PCID2 POLR3A SLC35A2 RAET1G ADSS KCNIP2 ARID1A SLC37A1 LPCAT2 SLC29A4 CNOT4 COMMD4 CAPN7 DSTYK COMMD2 CCDC93 SLTM KLHL28 MCM3AP LIN52 AK6 SEC22A EIF4A3 CCDC22 CTSL1 ACAD10 OR2T11 EPHX3 COMMD3-BMI1 SNX27 OR5D13 ARPC4-TTLL3 ADAD2 TMEM8C ATL1 OTOS SCGB2B2 C1ORF68 NBPF6 KRTAP9-6 C9ORF171 ATAD3C FHL5 C10ORF131 NBPF4 PRMT7 LOC100289561 Daniloski et al. Cell CRISPR screen to negative hits Identification of required host factors for SARS-CoV-2 infection in human cells IL6 SH3BGR PRIM2 ACTRT2 UBXN2A POLA1 CHRNB1 NOL7 MED14 HOXC6 ZNF850 RPL19 SIK2 SIN3B TUBG1 DLGAP5 CDK1 KIF4A PRDX1 DOCK1 SCD NCAPG KLF16 RHOD RSPO4 OR5T1 OR5K1 COLEC12 CASC5 CCR5 C11ORF85 GRASP GATA2 SEMA3C RPL4 DNAJC8 RPS9 SEPT7 PSMB4 RBM7 NDUFV2 ATP5J2 RBM8A EGR2 GFAP SGIP1 ASB2 SELT ARMCX6 CKLF NAA10 TMEM50A CBX1 RPL32 PDHB APOBEC3C SRSF7 GSPT2 COL11A1 GRAMD4 VRK2 TULP1 MYL3 IL15 FES CDC42BPG ACTN4 CRISPLD2 ORM1 BOP1 WFDC12 ZNF426 SERPINB1 SLC6A7 SWT1 INSM2 P2RX5 MASP1 B4GALNT4 HIST1H1B API5 RNF13 SNRNP27 C4ORF3 HSPB11 KLHL21 COMTD1 ZNF524 TMEM91 DDA1 MAP3K13 SPRED1 UBE2Q1 AKR1C4 RALGAPA2 RRAS2 IGFALS POLB ANKRD27 IFRD2 MAP2K2 CLN5 KDELR2 TIAM2 MRPL41 MAGIX VPS13A ATP6AP1L KCNV1 PDLIM7 MRPL19 MYPOP GAR1 SUGP1 IPMK PTGES3L TBC1D22A PRPF40A MEX3D ZNF549 KIAA1841 RNGTT OVCH1 EED LUC7L VENTX AZI1 RUSC1 C9ORF57 DMRTB1 CWF19L2 ZNF595 DEFB110 CYLC1 SMEK1 ZNF480 CCDC172 KRT77 LCN8 MTPAP C9ORF92 TPH1 PSMA8 LUZP2 SPHAR CXORF48 RUFY3 HMX3 ZNF232 GPR114 Top 32 genes involved in SARS-CoV-2 infection from genome-wide CRISPR screen of Zhu et al. A genome-wide CRISPR screen was performed, and 36 top genes involved in SARS-CoV-2 infection were identified. Top genes are taken from Figure 2C. Zhu et al. (2020) The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission. bioRxiv, 8/25/2020. CTSL NPC2 ACE2 RAB7A TFE3 ARPC3 VPS35 COMMD8 CCDC53 ASCC3 KIAA1033 ARPC4 ACTR2 ACTR3 VPS29 NPC1 COMMD3 CCZ1B COMMD10 C16ORF62 WDR81 COMMD4 COMMD2 CCDC93 COMMD5 KIAA0196 C18ORF8 COMMD7 CCDC22 COMMD3-BMI1 WDR91 CCZ1 40 SARS-CoV-2 host factor genes from genome-wide CRISPR screen in Huh7 cells from Baggen et al. Genome-wide CRISPR knockout screens in human Huh7 cells were used to identify host factors for SARS-CoV-2. Genes taken from Figure 1D; mild SARS-CoV-2 selection (low stringency). Baggen et al. (2020) Identification of TMEM106B as proviral host factor for SARS-CoV-2. bioRxiv, 9/28/2020. CEP350 PMPCA TMEM30A CAMLG BAP1 EXT1 KRT19 RPL19 ZBTB32 PSMB7 CAPSL FGB PTDSS1 GLUD1 SALL2 ITGB6 PIK3C3 CCZ1B ACSL4 PINK1 DNM2 SERPINA11 MAPK4 AHCYL1 HSD17B12 MAPKAPK3 PHIP NR2F6 DSTYK TMEM41B PTPN23 DTD1 CCDC176 KIAA1598 RSG1 POP1 LRRC71 MTRNR2L9 THBS4 OSBPL9 178 positive hits from CRISPR screen of Heaton et al. in A549-ACE2 cells A genome-wide loss-of-function CRISPR screen was used to identify essential host factors for SARS-CoV-2. Genes from Supplemental Dataset 2, Column J. Heaton et al. (2020) SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2. bioRxiv, 8/14/2020. https://pubmed.ncbi.nlm.nih.gov/32817937/ PIK3R2 RAD23B NMI TINAG MPP5 ARRB2 RALA NF2 SLFNL1 ESR1 FAR2 RNF41 SLC7A9 AGPS ATM TMEM176A RAB7A PCSK6 CD4 G3BP2 ITFG1 NSMCE4A CD55 MNAT1 TPRG1 LSM12 ZEB2 MYO5B GPR107 RGS12 UNC50 CPVL SLC38A10 AURKB PTCHD1 MYCL RHOV SLC45A2 SCAF1 H2AFX SFT2D1 CDH22 GDF1 TPPP3 SEMA3C SLC12A2 RAB5A NLGN4X SCARA5 ADORA1 ODF3 SGIP1 ZSCAN9 CCDC89 L3MBTL1 TMEM258 OST4 PHLDA3 YIPF3 MRPL16 PPP3CA NDUFA9 SOSTDC1 AKR1B10 SIK1 TMEM115 NDST3 FCAMR DDX43 RASD2 CCDC77 MEIS2 EIF2B4 EMP1 MRGPRF NONO ACTR2 XKRX PDK1 NUDT10 DNAJC5G ERVV-1 PCDHGB2 CRP TBX2 MLLT3 GOT1L1 RNF181 CA6 SLC35C1 REV1 PRADC1 MDH1B NISCH GPATCH3 SLC13A3 ATP1A4 AVPR1A DUOX1 PIWIL1 ETV3L KCNH3 SRPK1 FAM227B NXPH3 SENP6 UGT1A1 SCARA3 S100B SLC18A2 UGCG TTI2 TIMM50 DNAJC17 NYNRIN CHRNA5 CSN3 TXNL4B CSRNP2 LRRN3 GAMT DCAF17 CRNKL1 TAF6L ZMIZ1 LIN54 SZT2 BRF2 ZBTB3 CDK14 FANCE GPALPP1 SUPT6H OXCT1 ARHGEF9 ZNF121 ACAP2 BROX CEP128 GALNT15 GFRA3 ZAK PDP2 NHLRC2 SAV1 TMEM98 GYPA CCDC25 PNPLA8 DIRC2 NR2C1 TCTEX1D1 TTC27 ZIC1 ZNF287 LYRM4 CGB2 HELQ BUD13 SEBOX BCMO1 LRIT3 GRTP1 KRT40 TAL2 SLC5A7 FAM189B ANKRD34C F8A3 R3HDM1 LIPK MBOAT4 RNF180 FAM229A METTL20 RBM44 VPRBP ZNF730 192 negative hits from CRISPR screen of Heaton et al. in A549-ACE2 cells A genome-wide loss-of-function CRISPR screen in A549-ACE2 cells was used to identify essential host factors for SARS-CoV-2. Genes from Supplemental Dataset 2, Column D. Heaton et al. (2020) SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2. bioRxiv, 8/14/2020. https://pubmed.ncbi.nlm.nih.gov/32817937/ PSMD8 KPNA2 PF4 ETV1 ZP2 ESR1 RAB8A CLDN15 BTNL8 PSMD4 CLCC1 FBXW12 CHRNB1 CRYBB3 HSPBAP1 PTPN4 SLC25A40 SLC25A16 FN3K RPL14 MTRNR2L8 LURAP1L EIF3B HK1 MMP19 NTSR1 CEP78 B4GALT2 CYP4V2 ACOX1 HGFAC PRLHR CASZ1 PGLYRP2 BARD1 SKA3 THEMIS RAD51AP1 MYOM2 GRIA1 SLC17A6 CYP4B1 MYL12A S100A4 EIF3I ADAMTSL2 SMAD4 METTL14 RAB3GAP1 CECR6 MT3 IL13RA2 PCDHA9 LCMT1 SDC2 PAM MCEE POP5 SF3A3 YTHDF1 METTL25 ZDHHC15 TCEB1 AVIL ISOC2 GRP ASRGL1 TRHDE SP100 CNNM3 DNAJC3 WFDC12 CCDC173 RPL23A ERBB2IP ASPDH PRODH2 SH3TC2 HAND1 FATE1 PRUNE2 WDR82 USB1 APOBEC3F PRMT1 SP140 TTC4 IFT20 USP4 RNF115 NUDT8 CCT6A NSRP1 RPF1 ALDOC CEBPZ BRIX1 KCNC4 CHST3 TRAPPC6A PYCR2 ELK3 RHBDF1 SPRED1 WDR74 PLIN3 HSD17B3 SIRT3 GANC POU3F4 ATG13 OR2V2 VPS16 STRADA ZSCAN25 AEBP1 SENP8 VPS4A GTF3C5 SNRPC SCGB1D1 GINS4 FAM127B STRBP MYSM1 RNPC3 UST ZNF771 ZSCAN29 RBM5 PANK3 CPEB4 SPA17 ACOX2 BPHL RAB3B TNPO1 SMC6 ZMYM1 REM1 BARX2 SHF BRD3 PLA2G10 CCSER2 POLL PPP6C NUDT4 POM121 CLK2 COQ7 MKS1 C1GALT1 SKAP2 SPSB2 DIRC2 ZNF638 FAM204A KRT77 TPH1 GOLGA8O PRAC TPH2 RBM26 GPR133 AGAP9 HOXD8 CERS3 CGB POTEJ ELMO2 CMTM1 CAPN9 HIPK4 GADL1 NBPF24 PPAPDC1B YY2 DNAH2 SAG WASH1 LARGE VCY1B ST20-MTHFS TMEM223 MKX ZFP69 KCTD17 SLX4 KRTAP23-1 SLC25A18 MAD2L1BP Top 437 positive hits from genome-wide CRISPR screen for SARS-CoV-2 for 37 deg C from Schneider et al. A genome-wide CRISPR screen for SARS-CoV-2 was performed to identify host factors at 2 different temperatures. Data from Supplemental Table S1, Table S1A. Schneider et al. (2020) Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks. (bioRxiv, 10/08/2020) CSNK2B ATE1 ATP13A3 SEC14L1 CTSL COMT SUN2 CAPN2 PPP2R1A SCAP VPREB3 ACE2 SLC16A8 EP300 CRYBB2 DDX1 CDX2 SLC5A1 FURIN ZBTB7B GNG5 GPAA1 NFKB1 HMOX1 RAB14 HNF4A MPZL3 BAIAP2L2 GIGYF2 PTX3 EIF4E2 CYB5R3 TRIM28 CRYBB3 WFS1 HS2ST1 IL17RA RAB10 DPH5 MAPK1 FAH SLC33A1 MGAT1 CHEK2 KLF5 EXT1 YAP1 ELF3 KIAA1671 CHCHD10 TMC8 PARVG TM9SF3 APOL1 SEC24C CORO1B GGA1 NDST1 APOL2 RHOB CLTCL1 LDLR KIAA0930 TDRD9 BCAT1 KIF4A MPND NAGA NRIP1 SCD PTPRS BMPR1A KLF16 B4GALT7 ZNF707 PGAP2 OSM MED23 JMJD6 HORMAD2 PYGO2 NFIC SAFB DGCR8 TSPY2 OR2M7 RGP1 DGCR2 PICK1 CREBBP OGFR GRAP2 ASF1B UPK3A CLEC4A RAC2 NCAPG2 USP18 LRRC3B NEFH P2RX6 AHR SMDT1 CTBP1 RAC1 ELOVL5 HMGCS1 PSMB9 MED18 CLDN5 SH3BGRL POLDIP3 GDI2 JTB ARF1 PIGQ DNAJA1 TMED10 ELOVL1 NCF4 RPS3 VPS26A OAT TMED2 RFPL1 CECR6 RFPL2 RFPL3 NSG1 CYTH4 TBC1D10A SLC2A11 TSC22D2 BTAF1 LCMT1 MIF CNOT10 BRE TFPT AHCY SAR1A UCHL5 VRK1 PIGP SSB CHTF8 SDF2L1 CCDC117 GPR89A ATP2C1 YDJC FAM13A APOBEC3C GP1BB TTC32 ZNRF3 MN1 GAS2L1 MSMO1 SALL1 SCAF8 MED10 GLCE UHMK1 MVD SNRNP40 CHRNB4 PIGT CSK EXTL3 ASCC3 DERL3 PIKFYVE ATP6V0D2 TFRC HSCB DCPS MBNL3 CRKL HERC1 RASL10A COG3 ILK RNH1 SRSF5 ST6GAL1 SERPIND1 PIGA SEC14L2 GOLGA6L2 GAL3ST1 VPREB1 NCOA7 CATSPERD GNA12 SIAH1 DHX36 PLA2G6 RAB35 EXOC1 NPC1 EGLN1 PARP1 RTCB AP1B1 UGP2 TOM1 EXOC2 TTC4 PPCS YIPF4 SYN3 CCZ1B CIAO1 DEGS1 THAP7 XYLT2 HIRA MED24 MED6 ACSL4 PRAME SUSD2 PPP2R2A ANKH WDR81 DGCR6L PRODH MFNG STK24 NBN PARVB MICAL3 URB1 LZTR1 GUCD1 TAB1 SH3YL1 RAB6A SREBF2 ECEL1 EWSR1 RFX6 ZBBX TSC2 PLEKHA8 TMEM211 DRICH1 TXNDC2 APOL5 VAC14 CARD10 PRKDC TMEM106B SLC30A1 BCL2L13 GPC3 PPP2CA GTPBP1 EXOC4 RANBP1 OSBP2 GSTT2B FLVCR1 PATZ1 MTF1 FZR1 PNO1 XPO5 GRWD1 TOP3B SUPT3H TXNRD2 GTF3C4 USP24 NFRKB SETDB1 CNOT4 GGNBP2 ZFX PCYT2 SLC25A1 SYNGR1 PTAR1 UBN2 PYROXD1 TRIM36 WRAP53 C1QTNF6 DGCR6 ZBTB45 BRAT1 TAF6L MED13 TAF5L LIMK2 HTRA2 MED16 ZBTB7A LRP5L FAM20B CFAP20 NIPAL3 DOHH GTF2H4 ATP11A TTC28 TMEM41B MBTPS1 UPP2 EIF3M WDR26 LUC7L2 EXOC8 MICALL1 CLASRP MBTPS2 PIGX PDCL ALG6 RNF126 MGAT3 COG8 DPH3 EPT1 TRAPPC13 ZMYND8 SUSD1 SLC35B2 PDS5A PDS5B LYAR B3GALT6 ARMC5 KIAA1109 ZNF511 CABIN1 FAM134B EXT2 QRICH1 CLEC16A SLC39A9 RPRD1A PGGT1B TRABD MED15 ADO KLHL22 ELFN2 KDELR3 DCAF10 NCBP2 JAGN1 SAMD4B CCDC132 FAM204A TMEM206 N6AMT1 CECR5 MEI1 HOXD1 SMEK1 SPHAR FAM189B ELMO2 LARGE KCTD17 SLC25A18 INPP5J TSSK2 DUSP18 TRMT5 YRDC LOC101929372 RTEL1 ASUN LOC388849 NENF MED12 ZNF74 WDR73 44079 RPP21 TOE1 COG2 SEC14L3 KDM8 SAP25 INO80C PIGC OR4F3 UBE3D KCNJ4 44081 43896 DEPDC5 SPAG11A CHADL TBX1 TADA1 SUPT7L GSC2 FAM175B KIAA0020 TSSC1 PIWIL3 ACTR5 TRMT61A RIMBP3C GP5 VPS33B CLDN25 COG5 TMEM191C GAB4 MPPED1 COG7 ARV1 B3GAT3 CCT8L2 CSTF2 XKR3 LRRC74B IFT27 RIC1 FAM227A CECR2 COG4 OR51A7 CEPT1 AMER1 PHF21B GPR89B LOC400927-CSNK1E PMF1-BGLAP CCDC157 TRMT44 Top 772 negative hits from genome-wide CRISPR screen for SARS-CoV-2 for 37 deg C from Schneider et al. A genome-wide CRISPR screen for SARS-CoV-2 was performed to identify host factors at 2 different temperatures. Data from Supplemental Table S1, Table S1A. Schneider et al. (2020) Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks. (bioRxiv, 10/08/2020) NUP210 UBL5 EEF1A1 MPHOSPH10 SARS2 ATP6AP1 PRIM2 VCP CISD3 EIF2S1 EXOSC8 TUBGCP2 YWHAZ NUP62 NR1H4 UBE2D3 MIB1 SLC13A2 TUBGCP3 SLC22A9 AP3B1 AATF ZC3H18 MRPS2 SARS DYNC1H1 TBX10 RNF41 GOLGA2 MRPS27 HOXD12 POLA1 FASTKD5 TUBA1C ACTRT1 SPTBN2 ARL6IP6 NUTF2 VARS MRPS25 ISYNA1 PRIM1 SDE2 BRCA1 TMUB2 FOXA1 FAU PABPC1 PMPCB MUC17 POLA2 NUP88 NPLOC4 RCC1 EXOSC5 SBNO1 AAMP NUP85 TBKBP1 NTS PTGES2 GFER CDK2 STAT6 ABHD11 BRI3 SPTLC1 NUDT6 FARS2 GADD45GIP1 TFAM YME1L1 RBM39 ATP6V1B2 NDUFB6 SF1 EXOSC4 FECH NAE1 ENO1 DCTN2 NDUFA10 HIST1H2BH SPATA5 LSM12 RPL14 THRB RPL41 AQP5 TPT1 RPL37 COX6A1 RPL24 ZEB1 HIST1H2BD RPL39 ATOX1 KIAA1143 PTPRZ1 TMPRSS11E DCDC1 ANKRD13D OGDH UNC93B1 MAN2B1 TOMM40 MBD6 PDCD11 VPS37C SLC3A2 XAB2 LRP1 EIF3B CMTM6 RHBDD2 ACLY NDUFB5 TOP2A CDCA8 CLSPN MRPL12 TUBG1 AURKB DEPDC1B NDUFS7 SPAG5 AP2S1 STAC3 VDAC1 MRPL15 CDC25A ESPL1 CDC6 VPS25 HJURP DYNLL1 TTK CDC45 CERS6 NKIRAS2 PRELID1 MRPL51 ESRP2 ZFPM1 ATR RMND5A STAT5A CYCS HMGA1 ITGA2B RARG MYO19 PPP1R37 WDR7 PRICKLE1 SOX9 ABI3BP HNRNPH1 IPO9 CTR9 WDR5 OR5AS1 FZD9 STK40 MED25 KMT2B RXRA CENPK DUSP13 AGAP2 HCST OIP5 ECT2 TRAIP INCENP COCH CHAF1A TIMELESS UNG STAT2 TCIRG1 PPA1 PDE2A IQCH SPAG4 FTH1 UQCRB HNRNPM TUBA1B CHMP4B COX17 TXN RABGGTA GSTP1 PCBP1 GATA2 IRF9 SMAGP DAZAP2 MYH1 DRAM1 RPLP0 UQCRC2 P4HB H2AFZ LUC7L3 SNRPD2 PSMC2 ARPC3 NDUFS3 VPS28 C1QBP PISD NDUFS6 MATR3 NDUFB3 NDUFB11 EPC2 MBNL1 SP3 PRPF19 NDUFB7 NDUFA2 RAN BMS1 PSAP KLHDC3 RNPS1 NDUFA1 GPI NDUFA6 MBLAC1 CFDP1 SRSF3 WDR45B DDX39B ANAPC5 NXF1 GLRX5 HAUS4 CHCHD1 MRPS18C NDUFB10 COX14 HIGD2A ZC3H12A SLC25A25 SLC5A5 TRIM43 AOX1 KLHL41 QPCTL BAMBI CHAC1 KANSL1 TSPAN31 NDUFS2 MECR ZNHIT3 MRPL34 MRPL46 LAMTOR2 MCRS1 WBP2 ATP6V1E1 CHMP5 CHCHD4 RBM42 OXA1L MRPS33 POLD2 AP1S1 TUBA3D UBE2N COPRS SDHAF2 GSS POLR3C MRPS35 PSMC1 HAUS7 NDUFA8 ATG5 POLR2J ACTR10 RPAP3 MRPL17 RUVBL1 MRPS30 NUP107 UBE2G1 EPRS DYNLL2 MRPL1 PFKM HSPE1 NDUFA9 YAE1D1 MRPL11 MRPL18 SLC25A46 HIST1H2BE WDR11 NUDC THOC1 KIAA1683 HTR1D TNP1 COMP NOA1 RRAGC DPH2 SRSF6 CEP192 CENPC RWDD4 ZBTB2 MRPL47 NUP43 POLR3H MST1 SLFN5 MARS2 NCKAP1L SLC6A4 ERMN SGK494 GOLGA8H PRPF38B BBOX1 MCM4 VPS41 MCM7 RBBP5 SNRNP25 MAD1L1 ALYREF ZNF623 PET117 EIF3A GPATCH1 XRN1 MRPS11 RBMX ANKRD49 USP44 CCNT1 SPAG9 KIAA1033 NIPBL NDUFS1 ATRX RALB PPP1R10 THOC2 NAA25 WEE1 ARPC1B COPG1 CSTB PATL1 RPL23A U2AF1 NDUFB4 CHP1 TCEB2 SNRNP200 CRLF3 PPTC7 TRIB1 DKK4 MBLAC2 HIST2H2BF FCGR1B RTN4RL2 PLSCR1 NCF1 HOXD13 STAB2 ITGA6 PSMC4 SKP2 MOG COPS4 POP4 NUBP1 VTA1 COQ9 POLR2H SNF8 YEATS4 RNF113A RER1 SEC13 TRAPPC4 SUPT4H1 GATB COPS3 VPS36 SLC31A1 COX11 TSG101 GDF5 HHEX CREB1 PRMT1 MRPS12 ARCN1 UBAP1 GRSF1 STARD3NL LARS2 COX16 TMEM199 UBE2Z GPN2 COQ2 COX20 DHX35 FADD SUCLG1 RAB21 RNF115 NNT GTDC1 ATG3 CHMP1B AURKAIP1 COA4 CLCN7 CCT6A CHMP3 CDC42SE1 COA3 MTRF1 SLC25A10 CCS GTPBP6 COMMD10 NDUFAF4 USP36 POLH IRF2BP1 EHMT1 CUL3 NFYB U2SURP ZC3H15 GTF2E2 WDR75 PTCD3 BRIX1 MRPL33 ASNA1 PLEKHM1 BEST3 BTBD9 SKIV2L CYC1 BRD9 TAF1 HARS2 VPS13D SLC39A7 TIMM13 LETM1 SMPD4 STARD3 TCF25 TBCD GLT8D1 PCID2 CTTN AFG3L2 NRF1 EMC7 PELI3 FAM91A1 WDR1 HSD17B3 KEAP1 FXN COL4A3BP PRMT5 CHD8 NDUFAF6 NCOA2 SSRP1 ACACA HIP1R CDC27 EHMT2 MEN1 NME6 TEX43 RNF121 ATG7 FOXA2 RPTOR POLR2F KAT2A SPDYE6 COQ10B SENP6 AQR ADIPOR2 MRPL40 HK2 RPS6KB2 PDCD6IP PPM1D TUBGCP5 HYPK RRAGA RFC1 PSMG1 ABTB1 LRPPRC AP1G1 MRPS26 BAAT PHF6 POU2F1 TGIF1 HSPA14 NFYA NAA15 MCM3 SOX4 TTI2 GLS2 SART3 WDR3 SKIV2L2 TMEM138 THOC3 UTP18 MRPL4 DHX37 MYBBP1A MRPS34 CDK7 SEC63 SNRPC WDR70 AKNA GTF2H1 HSPA9 COX7B NDUFS5 AHCYL1 CS TMEM70 IMP3 GINS4 SDHC MRPL30 OSBP NOP2 TNPO3 THAP1 TXNL4B RBM33 ARID3B WAC KDM2A BAHCC1 GPS1 MRPL41 MRPL3 THAP11 MRPS21 DDX28 NDUFB8 KIAA1211L DTD2 KLHL13 PHIP HOXB9 INTS5 HCFC1 OSBPL10 ZBTB40 PDE12 RRP15 INTS7 BTBD7 GRAMD1A ZDHHC24 RPUSD3 SETD1A TJAP1 AP3D1 PRKRIP1 ATP5A1 MCM3AP NDUFC2-KCTD14 MRPL43 UQCC2 ATPAF2 ATL3 SHANK2 LRRC37A SUPT6H ZNF112 COA6 PYURF VMA21 TM9SF4 HDAC11 MRPL14 IST1 PRPF4B HIST1H2BN HIST1H3E ATP5F1 KIAA2026 HIST1H2AI CDK5R1 MRPS18A STK32B MRPL44 ZRSR2 RBM19 CIZ1 VPS13C PLK4 PPM1E OSBPL11 ADGRL3 OPA1 MMP28 DIMT1 KIAA0196 MINOS1 BPTF ZMYM3 ATXN7L3 METTL1 PDCD2 GFM1 NR6A1 EIF2B2 NAT10 GNL3L UROS MRPS24 NUDT4 UQCC3 IMMT SUGP1 ABT1 TACO1 COQ7 COA5 CCDC87 LYRM7 FAM171A2 CPSF3L CCDC22 PTPN23 DHX38 PAM16 HAUS3 GPRIN1 SRRM3 CNTROB MRPS17 CCDC59 NUPL1 CNOT1 DPAGT1 MRRF CARNS1 RTN4IP1 TTC37 CAND1 PTRH1 PAFAH1B1 IKZF4 ADAMTS20 CBWD5 ZNHIT2 ABHD15 CCBL1 TAZ CPSF6 LRRC71 GOLGA8O WASH1 UQCC1 LRRC57 PPIAL4G CERS5 SPDYE2B PRAMEF15 MTO1 PDE6G MRPL53 TAF4 KRTAP4-7 TEFM KRT85 SLX1B KANSL2 SURF1 RNMTL1 SLC17A8 PCGF2 FAM122A UBE3B USP17L30 CCDC43 PROB1 PDE11A LOC101060389 FASTKD2 POLR2D PGA3 PPP1R32 NRDE2 ISY1-RAB43 SS18L2 PSTK ZNF99 EIF2B3 DDX46 YBEY TBC1D3C TRRAP PPP1R35 ANKRD20A1 COX18 AGAP5 CRHBP MRPL49 FTSJ2 LOC730183 NUTM2B XRCC6BP1 SECISBP2 BCDIN3D TTC24 OR10AD1 PPIAL4E TMEM116 FKBP6 GPR152 MEAF6 OBP2A PARL PEX12 WDR83 LINC01272 YEATS2 AGPAT6 TMEM261 LACRT METTL17 LCN6 GTPBP8 NELFCD LIMS3L MOSPD2 MRPL48 HNRNPCL4 MRPS18B KIAA1429 GOLGA6L1 PTCD1 43899 MRPS31 Top 389 positive hits from genome-wide CRISPR screen for SARS-CoV-2 for 33 deg C from Schneider et al. A genome-wide CRISPR screen for SARS-CoV-2 was performed to identify host factors at 2 different temperatures. Data from Supplemental Table S1, Table S1B. Schneider et al. (2020) Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks. (bioRxiv, 10/08/2020) CSNK2B CANT1 RAB2A UHRF1 APC CTSL PPP2R1A MOGS VHL SCAP NPC2 ACE2 EP300 MIPEP DDX1 CDX2 OR6Y1 GNG5 GPAA1 HNF4A GIGYF2 EIF4E2 PRSS50 ALG8 TRIM28 CRYBB3 VPS39 VPS11 HS2ST1 MAP3K1 RAB10 DPH5 C1D DOLPP1 NEO1 PITPNC1 SLC33A1 ENY2 MGAT1 MKRN2 CHEK2 RPS16 KLF5 EXT1 ELF3 KIAA1671 KHSRP TTC14 PGD TM9SF3 APOL1 NDST1 GANAB UNC50 APOL2 CLTCL1 LDLR MTCH2 GAPDH RMI1 ACO2 AMPH OSTC LDHA TPI1 NRIP1 BMPR1A KLF16 ABCC4 B4GALT7 TGFBR1 PGAP2 OSM MED23 IMPA2 GIPC1 SORCS2 HORMAD2 SAFB DGCR8 RGP1 CREBBP MBOAT7 IFIT1B SIGLEC1 USP18 NEFH ITGA8 MYH7 PCBP2 COASY HMGCS1 CLDN5 MAT2A GDI2 ACAT2 EIF5A BRK1 JTB ARF1 CDIPT PIGQ TMED10 VPS26A ARL1 SMAD4 OAT TMED2 CECR6 SELM TAGAP IFNA5 NFKBIZ BTAF1 NR2C2AP ZBTB8OS LCMT1 CNOT10 NRBP1 BRE STIP1 SAR1A VMP1 POLE3 UCHL5 ZW10 VRK1 PIGP SSB TMEM251 GTF3C6 PAPOLA MMGT1 USO1 CHTF8 GPR89A TOB2 GP1BB SQLE MED10 GLCE MVD ODF3B SNRNP40 NAGPA CSK EXTL3 PIKFYVE HSCB TRIML1 DCPS RHNO1 UFM1 CRKL DEFB132 KLHDC2 SOD2 COG3 EIF4A1 COPE ILK RNH1 SRSF5 CD68 DHX36 PLA2G6 AASDHPPT EXOC1 SURF4 QRSL1 PPA2 SUPT20H RPE UBA2 SCO2 CTCF NPC1 DICER1 EGLN1 RTCB TXN2 UGP2 TOM1 EXOC2 PARS2 TTC4 PCDH11Y CMPK1 CCZ1B SMARCB1 FIP1L1 THAP7 MTG1 EFTUD1 XYLT2 HIRA MED24 VEZT CCAR1 DHX29 PPP2R2A ANKH WDR81 DUS3L POLE4 MVK FDXR MFSD12 TELO2 STK24 LZTR1 TAB1 TMPRSS6 RNASEH2B SNAP29 RAB6A HNF1B SLC7A6 SREBF2 EWSR1 PLD5 SIPA1L3 DTYMK PGM3 NME6 TMEM211 ZFAT CYP2D6 FIG4 MEOX1 VAC14 CARD10 DHPS DROSHA TMEM106B SLC30A1 BCL2L13 GPC3 PPP2CA EXOC4 UBXN7 FNTB TGIF1 PDAP1 MTF1 FZR1 TAF1B XPO5 TSEN15 GTF3C5 TRMT6 CENPO AKR7A2 THOC5 UGDH MAP2K7 CYB5R4 DARS2 GTF3C4 SETDB1 HMG20A BRPF1 ZFX TADA2B SYTL3 PMVK DNLZ SLC25A1 GMPPB PTAR1 CEP44 UFSP2 PYROXD1 BRAT1 TAF6L MED13 TAF5L LIMK2 HTRA2 NAA38 WDR18 NSMCE1 MED16 ZNF592 DNAJC25 MON2 NEK1 RBM5 ZBTB7A FAM20B CFAP20 DOHH TMEM41B MBTPS1 MED21 DDX6 LUC7L2 MBTPS2 MSTO1 ALG6 MAN1A1 SMC6 RNF126 GTF2A2 COG8 DPH3 EPT1 NKTR SLC35B2 PDS5A PDS5B B3GALT6 KIAA1109 DOLK FTO EXT2 CLEC16A ARID3A SPPL3 ZFAND6 SLC39A9 MED15 SPATA2L STK19 CTDSPL2 KLHL22 CCDC101 CTDNEP1 SRRD JAGN1 CCDC132 OPCML FAM204A TMEM206 N6AMT1 MEI1 SMEK1 SPHAR WDR91 CCZ1 TSSK2 TRMT5 YRDC MED12 WDR73 RPP21 TOE1 COG2 PIGC UBE3D TADA1 SUPT7L GSC2 TSSC1 ACTR5 TRMT61A VPS33B COG5 GAB4 COG7 B3GAT3 CCT8L2 LRRC74B RIC1 COG4 OR51A7 GPR89B YBEY PEX12 MED28 ASB16 NSMCE2 CFAP74 SMG9 TAMM41 DEFB128 XKR5 GATC OR2L5 RAD9B RPUSD4 RNF215 DBH PLEKHD1 OR2L8 MRE11A ICE2 DPH6 KLHL7 Top 797 negative hits from genome-wide CRISPR screen for SARS-CoV-2 for 33 deg C from Schneider et al. A genome-wide CRISPR screen for SARS-CoV-2 was performed to identify host factors at 2 different temperatures. Data from Supplemental Table S1, Table S1B. Schneider et al. (2020) Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks. (bioRxiv, 10/08/2020) UBL5 BCL2L1 MPHOSPH10 TMEM247 HSPA5 ATP6AP1 PTEN PRIM2 MAP1LC3A BCAR1 RPL36 KPNB1 EXOSC3 KPNA2 EIF2S1 EXOSC8 TUBGCP2 NUP62 UBE2D3 MIB1 TUBGCP3 IFITM3 SLU7 YIF1A PKM CUL1 DYNC1H1 UBA1 TBX10 SEPSECS GRPEL1 CRYGC HOXD12 POLA1 SPTBN5 FBL PHB2 NGLY1 COPB2 TUBA1C SPTBN2 ARL6IP6 NUTF2 VARS SAP18 MRPS25 PRIM1 SDE2 BRCA1 NT5C MEPCE FAU PLAT PMPCB TIMM10 PHB NUP88 NPLOC4 NEDD8 EXOSC2 EXOSC5 SBNO1 ALG11 AAMP CCDC86 VSTM2B UBE2I GRB2 NFS1 SLC7A6OS PSMB1 BRI3 GADD45GIP1 RBM39 ATP6V1B2 FGFR4 ABHD3 PAIP1 EXOSC4 CAMLG MCL1 PSMA2 RPS20 DCTN2 BPIFB1 RPL21 RPLP2 RAB40B RPS11 RPL27 MXRA7 RPL6 RPL37 RPS8 RPS3A CCDC80 RPL23 RPL13A RPSA HIST1H2BD RPS18 RPL7A RPL31 RPL11 RPS14 RPS27 SRRT SYMPK ANKRD13D UNC93B1 PTGER4 KSR1 TMEM127 PDCD11 VPS37C XAB2 SF3B4 LRP1 SMAD7 SMARCD1 RHBDD2 MYBL2 TOP2A TICRR CDCA8 CCNA2 CLSPN MRPL12 TUBG1 AURKB RBBP8 STAC3 VDAC1 BUB1B AURKA ESPL1 FADS1 CDK1 CDC6 BIRC5 ORC1 TPX2 VPS25 DYNLL1 CERS6 PRELID1 YPEL4 MRPL51 PSMB7 ZFPM1 ZNF830 CABP4 RMND5A FOLH1 MARS IGBP1 CNOT3 HMGA1 SRSF1 ITGA2B PSMD6 ADGRF4 MST1R LRP5 PNN CDK2AP2 CTR9 DHH INSL3 PREB PRC1 CATSPER1 WDR5 OR10V1 OR5AS1 NR2F1 PACS1 CENPK SMC2 ARMC7 CENPA CASC5 SPDL1 CHEK1 AGAP2 NSL1 GINS2 MMS22L NCAPD2 OIP5 PTPRCAP CENPI RACGAP1 TRAIP INCENP SYT12 CDT1 POLE2 COCH CHAF1A NTRK2 TIMELESS UNG CPNE5 TCIRG1 FAP IFI35 EGR4 UBE2L6 FTH1 UQCRB RPL8 TUBA1B ATP6V0C BAG1 PPP1CB TXN DTX3L EIF2S3 GSTP1 PCBP1 HIST1H2BI SMAGP DAZAP2 RBMS1 DRAM1 P4HB EIF3E RPL10A LUC7L3 RPL10 SNRPD2 PSMC2 ARPC3 VPS28 PRX ARL6IP4 PPP1CA PSMD3 NUPR1 NDUFB11 RPL18 EPC2 RPL35 SP3 PRPF19 PSMB4 RPL18A NDUFA2 SOD1 RAN TRMT112 ATP6V0B PSMA6 NDUFA6 MBLAC1 SRSF3 NDUFV2 ZFP91 GTF2B DDX39B ANAPC5 NXF1 HAUS4 CHCHD1 GPX4 ATOH8 CAPSL SLC25A25 NOS2 TAGLN3 CCDC155 TREX2 LRRC10B BAMBI CLCF1 KANSL1 NUP155 SNRPG SUPT16H PSMA4 MCRS1 ATP6V1C1 CHMP5 OXA1L POLD2 NKAP TUBA3D LSM2 RABAC1 RPA2 UBE2N TIPIN POLR3C NOP58 UQCRQ TOMM34 PCNA ZCCHC9 PSMC1 PTMA ATG5 DONSON POLR2J CDC7 SKP1 RPAP3 PSMA7 MRPL17 CCT7 RUVBL1 MRPS30 NUP107 MMADHC NAA20 TMSB10 HSPE1 NDUFA9 SSC4D NARS MRPL11 RPL34 PRPF8 RRN3 ZP1 EIF2B5 WDR11 NUDC HSPD1 RANGAP1 THOC1 SRSF2 PPM1H SRSF7 SPATC1L HOXA5 SRSF6 CEP192 LRRN4 CENPL MCM6 NEDD1 NECAP1 KRTAP4-6 NSF URB2 RPA3 ATP5G2 RPAP2 POLR3H SLFN5 SPATA24 ACTN2 CRACR2B IARS SGK494 GOLGA8H PRPF38B PAQR6 HIST1H2BL ORM1 MCM7 DHX16 LPGAT1 RBBP5 SMC3 SNRNP25 SNRPA1 SMG1 RFC2 HAUS6 BET1 RBMX TOP1 SPAG9 ASB8 GARS NDUFS1 SRGAP2C EIF2B4 TWISTNB PPP1R10 THOC2 SDAD1 ORC6 WEE1 COPG1 CSTB NAPA MDK RPL23A U2AF1 SEC61B TCEB2 KHDRBS1 XPO1 SNRNP200 RPS6 ZNF221 GRIN3A TRIB1 SPRYD4 ANAPC2 HIST2H2BF GPR17 FCGR1B RTN4RL2 PLSCR1 TRPM3 MMP24 NCF1 HOXD13 GOLGA6C POLR1A SF3B3 PSMC4 SKP2 MASP1 POLR2C NUBP1 TIMM23 VTA1 GOSR2 PSMD7 PHF5A SNRPD3 TADA2A POLR2H SCFD1 SNF8 YEATS4 RNF113A SEC13 TRAPPC4 NXT1 TUT1 TRAPPC5 SACM1L RGPD2 CSTF3 HHEX KARS CREB1 PRMT1 TAX1BP1 FAIM2 UBAP1 STARD3NL PLBD2 COPA HAUS8 ELL PSMC5 TMEM199 PRPF6 RBM22 GPN2 USP39 SNW1 TP53RK SEC16A FADD FAM32A RTFDC1 TMX2 PPM1A USP17L11 ATP6V1H ARPC1A BUD31 CDK5RAP3 CLNS1A CCT6A CHMP3 CTNNBL1 CCS DDX54 IRF2BP1 DCAF13 TSPAN5 FLCN SETD8 AHCTF1 CUL3 NFYB ZNF326 GNL3 ASNA1 TAF1C ZFYVE26 CCDC114 RRP1 CYC1 VPS13D SLC39A7 TSR1 LETM1 STARD3 TCF25 NOL8 UTP6 URB1 PCID2 LMBR1L AFG3L2 RSAD1 RNF123 PELI3 PC DHX9 WDR1 GCLC ACTN3 AGXT2 GDNF COL4A3BP SSRP1 TDRD6 TXNRD1 CDC27 MEN1 DDX27 RNF121 GOLGA6L10 BCL2L11 FOXA2 POLR2F PPIAL4D SPDYE6 COQ10B AQR HK2 RPS6KB2 PLD1 TRAPPC11 TUBGCP5 UHRF1BP1L HYPK LRPPRC ANKLE2 AP1G1 RBM4 SAP30BP GBF1 PLGLB2 MRPS26 KLB GAGE2B MAP3K2 NFYA MCM3 WWP1 PRPF38A WDR3 SKIV2L2 PRPF4 TEX10 THOC3 NUP205 POLD1 DHX37 LSM4 IPO4 WDR70 H3F3B HSPA9 SLC35B1 RILPL2 DNAJC17 CS TMEM19 IMP3 GINS4 PFKFB4 KANSL3 IGHMBP2 TNPO3 THAP1 TXNL4B ZNF407 ZBTB39 ORAOV1 KDM2A RBM14 GPS1 PXMP2 RPA1 PWP2 NDUFB8 REV3L DTD2 GPSM2 ZDHHC12 HCFC1 CACTIN NOC4L HAUS5 RFC3 RNF40 DNAJC9 ICE1 PAXBP1 NBPF8 ZNF341 NLE1 EIF3CL KCMF1 ZZZ3 CCDC174 ATP5G1 ZNF75A SNRPF SNRPD1 ATP5A1 NSA2 ZBTB3 ATP6AP1L MCM3AP EXOSC9 MRPL50 ATP6V1E2 LRRC37A SUPT6H TM9SF4 HNRNPU SPCS2 SUOX PRLR XRN2 BAZ2A ARPC5L DDX23 SF3B2 PRPF4B HIST1H2BN SMNDC1 RBM19 CIZ1 LSM10 PLK4 CDC5L MMP28 MATN4 DDX49 NUS1 ZNF408 KIAA0196 DUSP11 ADRBK1 BPTF FAM222B EXOSC6 FTSJ3 HINFP CACNB3 UMAD1 PLA2G10 GFM1 EIF2B2 UTP14A NAT10 CLP1 GNL3L LSM8 EIF4A3 EIF1AX SMG5 CELA1 NELFA POU6F1 UQCC3 GAR1 KAT8 PSMG3 MSS51 TBX5 MKS1 PGM2L1 FAM171A2 SART1 CHMP6 CPSF3L TMEM132A WDR46 FAM89B MTBP COPS2 POLR2I PTRH1 CHERP PCDHB2 RAPGEF4 UTP11L CBWD5 ZNHIT2 ABHD15 DAGLA RPRML CPSF6 TPH1 GOLGA8O WASH1 MAD2L1BP PMF1-BGLAP PPIAL4G SPDYE2B KRTAP4-7 SLX1B SLC17A8 FAM122A USP17L30 POLR2D PGA3 PPP1R32 NRDE2 TRRAP ANKRD20A1 AGAP5 CRHBP BCDIN3D OR10AD1 PPIAL4E TMEM116 GPR152 OBP2A MOSPD2 KIAA1429 GOLGA6L1 POLR3B NUTM2F LRRC37A3 PGA4 AGAP4 GAGE12C KRTAP4-5 URI1 METAP1 TBC1D3B USP17L26 USP17L18 GINS3 OR10A7 ERCC3 CABP2 METAP1D OR5M8 POMZP3 INTS8 CT47A10 KLHL12 BBS1 KRT31 SCGB2A1 ECD OR6C76 CLEC18C GREB1L METTL12 KRTAP4-9 HIST2H3D NUTM2G ISY1 PPP6R3 GATS OR4F29 WDR66 ZNF236 TBC1D3H CIRH1A DDX52 USP17L29 CCDC141 PPP5D1 BTNL10 MED30 BRD8 OR52K1 C1QTNF4 LRRC41 ACTL10 ZNF559-ZNF177 DCTN5 SYNRG BTBD18 AGO3 CCNK CT47A6 SPATA31A5 MUC12 DHX8 DBX2 MGC57346-CRHR1 PTCHD2 TVP23C-CDRT4 SLC35G4 TBC1D3F ARL16 500 top upregulated genes for SARS-CoV-2 infection vs. mock from GSE161881 Vero E6 cells were mock infected or infected with SARS-CoV-2 at a moi of 2. At 8 hours post infection, total RNAs were extracted and subjected to RNAseq analysis. Upregulated genes were determined via Enrichr. Title: Transcriptome analysis to SARS-CoV-2 infection in Vero E6 cells. GEO contributors: Guo R, Zhang Y, Gewurz BE ADAMTS1 PTPN14 UIMC1 GDF15 HSPA5 CCL2 CCL5 EGR1 SQSTM1 BCAR1 PTBP2 IL1A CXCL10 ZZEF1 MAST4 ABL1 TPRN NEDD9 RUNX1 KLF6 RNF41 CLCN6 BRD2 SERPINE1 FRMD6 SNIP1 OAS1 CSNK2A2 FOXA1 HERPUD1 OASL NUP98 ISG15 MARK2 AKAP8L MAP3K1 ZNF503 FZD5 ND4L MYO10 TRPS1 RGS2 HS3ST1 LSM12 HES1 DUSP16 PARD6B TPT1 GATAD2B PNRC1 FNIP2 ZNF827 TET2 GADD45A PRDM1 EXPH5 MT-ND4 ZNF462 ARID5B MDM2 NACC1 ZNF316 C15ORF39 THBS1 HBEGF TBC1D10B SMAD7 RHOB SDC4 ZBTB43 LDLR IFI44 DDIT4 ELL2 STARD13 SPRY2 PPARG ARHGAP23 ZNF574 TNRC6C RAB11FIP5 NUAK1 FAM83H B4GALT5 MYC TUFT1 BMP2 NOTCH1 KLF10 KLF11 ZFP36L2 GADD45B CISH EDN1 PLAUR MITF FOXO1 PLEKHH3 IFFO2 DNAJA3 FAM83G EVPL ZNF217 LAMA5 FGF5 PRICKLE2 AXIN1 CAMTA1 ATF3 MAP2K3 MAP3K4 RGS3 PTH1R DGCR8 FOSL2 PHF12 KMT2B RERE SLC12A7 CREBBP TNFRSF1A HELZ2 NUAK2 BRPF3 PLEKHG3 OGFR SBNO2 MIDN RSAD2 IFIT1 IFIT3 DHX58 IFIT2 HERC6 IFIH1 PML PLEKHA4 SOCS3 NFKBIE NFIL3 PIM1 ZFP36 IER2 IER3 FOS IRF1 DUSP1 TXNIP NFKBIA JUNB JUN VEGFA S100A4 AMMECR1L JUND ARRDC3 PIM3 ERRFI1 CCNL1 WDR45B YTHDC1 GEM KDM6B DDIT3 AKAP17A DUSP8 SLC25A25 TRAF1 EGR2 IFNL1 PPP1R15A ABCA4 TNFAIP3 PLA2G4C TBC1D10A SKI AMOTL2 DUSP6 PPP1R15B NEURL3 LIF KLHL15 DUSP5 IER5 TIPARP IRF2BPL CSRNP1 BAMBI ZSWIM6 CLCF1 BHLHE40 TAF1D NFKBIZ TSC22D2 SERTAD2 CDC42EP3 PFKFB3 KANSL1 IL11 SLC25A33 SH2B3 PPRC1 MSL2 PPP1R18 DHRS2 GNA13 ZNF317 USPL1 DUSP10 PDE4B YTHDF1 ZNRF3 SAMD4A MARK4 ARRDC2 KLF3 IP6K3 HIVEP2 SFSWAP DNAJB5 ZBTB2 SHROOM4 REL MAP3K14 ABL2 URB2 SUPV3L1 RASSF3 ZCCHC2 MARS2 ZC3HAV1 MAP3K8 RNF139 CCNB1IP1 CXCL11 IFI6 FNBP4 PER1 ND6 DDX60 GBX2 BCL10 ST3GAL1 CCNT1 UBN1 PAPSS2 FEM1C SH3BP4 MB21D2 FOXC1 ETS2 PLK2 DUSP4 N4BP1 COG3 CERK DYRK1A SKIDA1 PRKAG2 GRAMD1B TRIB1 CLK1 SEMA7A NR1D1 TBX18 CDC14A REXO1 HS3ST3B1 SLC6A13 PLAGL2 RUBCN NXT1 CAMSAP1 AGO2 EIF2AK4 CREB1 MDM4 TBX2 SPEN TNFRSF1B PELI1 NFKB2 TGFBRAP1 OTUD1 SMURF1 FAM193B USP36 EHMT1 FLCN EPHA2 REV1 TXLNG TMCC1 HMGXB3 KLHL21 MEF2D ARID1B FIZ1 PPP1R3B TET3 RHOBTB2 EIF1B TANC1 SSH2 NOP56 CRY2 EPC1 PELO PLEKHM2 SPRED1 URB1 ANKRD17 RIPK4 KPNA4 PTPRJ CCN2 PER2 LMTK2 ZNF3 RREB1 ARID1A MRTFA KMT2C ZBTB18 ZBTB4 KDM4C ASXL1 PDGFB SETD5 ZBTB21 CHD2 TNFRSF10B SPRED2 EIF2AK3 FAM71A ZFAND5 FBXW7 UBIAD1 KCNJ8 PPM1D RC3H1 ZSCAN12 ZNF398 ZSCAN25 ZFHX4 SEC24A CRAMP1 FBXO11 CCN1 WSB1 GPAT3 ERN1 SOX4 MTF1 UTP15 GEMIN4 TOP3B CDK12 ZNF746 IREB2 ZNF142 USP42 POGZ ZKSCAN5 DIP2C ZC3H4 ZNF764 SCAF4 SETDB1 RBM33 GMEB2 ARID2 ZNF335 GGA3 CNOT4 ARHGAP17 ZBTB11 ZBTB48 ARID3B RNF111 RUSC2 RASAL2 INO80 BRPF1 MLLT10 AEN ZBTB24 LRIG2 ABTB2 ZSWIM4 ARHGEF28 FSTL3 CLK4 ACVR1 ANKRD50 UBN2 PPP1R3C ZNF608 HEG1 KDM5B INTS5 FRS2 ZCCHC14 ADNP2 PAXIP1 DIDO1 KAT6A SZT2 SOCS5 RAD54L2 PDZD8 PPFIA1 ZNF7 TNRC6A PPP4R3A ZSCAN29 RFNG ZNF592 ZNF778 GPATCH8 C16ORF72 TRIO HPS6 NOCT FOXN2 C11ORF68 NCKAP5L ZSCAN20 ZBTB7A RAI1 BICRA TLK2 TGIF2 ARAP2 FBXL18 PRAG1 KMT2D TENT4A MFSD14A CEP85L ZNF79 MED9 IRF2BP2 EAF1 GZF1 FOXJ3 DMWD ZNF408 NHSL1 FAM193A ZDHHC8 B3GALT6 FBXO28 RAB12 SPECC1 CHD7 MARCHF9 AFF1 ITPRID2 POLR1E KLHL26 DCBLD1 ZFY ATN1 SNAPC4 MICALL2 FHOD3 ATXN7 DAGLA YRDC ZNF74 RIC1 TRMT44 PCGF2 AGO3 STK35 IQCC MALSU1 ZNF853 ZNF823 RBM15B ND3 PPP2R2D FBXO42 CNTFR SETD4 CEMIP2 ALKBH4 MTMR10 RNF169 NCOA6 MIDEAS MIER2 TENT5B COX3 MAP11 GPR37 ZNF2 ZNF500 PALM2AKAP2 500 top downregulated genes for SARS-CoV-2 infection vs. mock from GSE161881 Vero E6 cells were mock infected or infected with SARS-CoV-2 at a moi of 2. At 8 hours post infection, total RNAs were extracted and subjected to RNAseq analysis. Downregulated genes were determined via Enrichr. Title: Transcriptome analysis to SARS-CoV-2 infection in Vero E6 cells. GEO contributors: Guo R, Zhang Y, Gewurz BE MYH9 GLA UBL5 IFNAR1 EEF1A1 OS9 HSP90AB1 PIGS ATP6AP1 CTSL GHITM YWHAQ EPB41L2 ETFA PRKACA CSDE1 KPNA2 CDH17 EXOSC8 ACADM NPC2 ATP6V1A RBL2 PDZD11 ACAD9 PPT1 RNPEP CYB5B ATP6AP2 MIPEP DDX1 SCCPDH NDRG1 HSPB1 SRP54 AP2M1 TUBA1A CTNNB1 RAB8A POLA1 GPX1 RAB18 CALM1 NUCB1 ERP44 TST ARL6IP6 NUTF2 POGLUT2 PMPCB MSN G3BP1 EXOSC5 AGTRAP STOM PLS3 HSPA8 CAT CDK2 G3BP2 MDH1 RBKS PSMB1 MTFR1 SCP2 PTTG1IP NDUFB6 ENY2 BTF3 ENO1 OCIAD2 POLR2B LAS1L UQCR10 TSPAN6 METTL7B CNN3 DSG2 EPCAM SCIN TMEM109 TSPAN3 ATP1A1 TMBIM6 BANF1 PDIA6 STMN1 LGALS3BP UQCRC1 PRKCSH PGD CD81 QSOX1 CYBA GANAB TMED9 GRN DDB1 PLK1 TIMP1 NDUFB5 TOP2A ZWINT TK1 CAPG CCNB2 SCARB2 CREG1 SHCBP1 SCPEP1 SPAG5 ALCAM LGALS1 MCM2 MRPL15 BUB1 GPNMB SHMT1 COMMD9 NDUFS4 MPDU1 LGALS3 ATP5PB NME1 TPX2 CCNB1 CDCA3 ACO2 CDC20 DYNLL1 PSMB2 PRDX3 SPATS2L TPI1 KIF20A PSMB7 ENPP5 CRIP2 AKR1C3 IGFBP3 CTNNA1 COL5A2 SERPINH1 MMP1 APLP2 SLC2A2 SLC7A5 ARHGAP1 HNRNPH2 CD63 PRC1 RAD21L1 RBM47 CDC25C FANCI FANCD2 ERCC6L PBK MELK NCAPG2 HMGB2 CIDEC BEX1 GINS1 CHRDL1 CDH16 DHFR TNFAIP6 LGMN IGFBP6 CLDN2 SLC7A11 AIDA EPHX1 CLIC4 PSME2 SPTSSA PFN1 HNRNPM TUBA1B AKR1A1 MYL12B CAPZB MYL12A SPARC SYF2 ATP6V0E1 GSTP1 ANAPC13 MORF4L2 DAZAP2 RBBP7 RPS19 BCAP31 CST3 MDH2 ITM2C ALDH1A1 MYH10 NDUFA13 PSMB6 PSMC2 COX8A PRDX5 ARPC2 PPP1CA PSMB5 LAPTM4A PAIP2 CETN2 COX4I1 EID1 NDUFB3 VIM PDCD4 SRP14 CNBP OAZ1 NDUFA5 PRMT2 SLC39A1 ROMO1 CALR PSAP MRPL28 RAB11A DSTN NDUFA6 RBM3 VDAC3 ANXA1 TMED10 NDUFA4 SRSF3 NOP10 POLR2K CETN3 NUCKS1 DYNC1LI2 OAT ACADSB PGRMC1 TMED2 CD9 RBM8A DAD1 BNIP3L AOX1 SERPINI1 ANP32A OST4 NDUFS2 MAGT1 ZBTB8OS POLR2G SUPT16H MMP10 MRPL46 PSMA4 RRM1 PSMD1 MPV17 ATP6V1E1 ATP6V1C1 CHMP5 CIB1 MRPL27 CRYZ ARL6IP5 MIF AIFM1 POLD2 DCXR IDH3B TCEAL8 AP1S1 SARNP MRPS9 DDX18 RPA2 MRPL13 LAMTOR5 PSMB3 ZNHIT1 TFPT CHMP4A STIP1 DPP3 TTC1 AHCY MAGOH COPS5 MRPL42 NHP2 ORMDL2 PSMD10 ZMAT2 SDC2 CDC26 LSM7 GSS MRPS35 ACTL6A UQCRQ ANP32E PCNA BCAS2 TIMP2 NDUFA8 ZDHHC6 NUP37 PCMT1 CAP1 BUB3 FAM107B SKP1 PSMD14 PSMA7 SSR2 RUVBL1 GTF3C6 ERH RPN2 NAA20 NDUFA9 PDHB DECR1 EPHA7 ETFB MRPL11 MFAP1 HSPD1 SRI IK ZNF385B ZMPSTE24 CD46 MCM6 MKKS SLIRP POLR3H ASNS TAPBPL SLC1A4 MMACHC MIS18A PDZK1 PCYOX1 GPT2 TM7SF2 RSU1 SERF2 CTSA COPE COX5B EIF1 HNRNPA1 CALM2 ACTR2 CD44 SPTSSB VTA1 VPS29 USB1 NCF2 ARL2 PARP1 CTSF GBA API5 USP5 UGP2 COPA ARPC5 IPO8 PHGDH FMC1 CRLS1 PSMC3 SPP1 YIPF5 MCFD2 TPM1 CALCOCO1 CMAS ALDH3A2 ATP1B3 ATP5MC1 ATP5MPL COPS6 CAPZA1 ATP5F1E BST1 ATP5F1A BECN1 CIRBP CDK5RAP3 ACAA2 KRT10 COMMD10 BCCIP PTER PDIA3 ITPA TRAPPC6A POLE4 THOC6 G6PD TPP1 PSEN1 UROD LRPAP1 CPA4 EWSR1 PTPRF DTYMK TMEM168 CISD2 POLR2F IVD PRKDC GALK2 CALU MCM3 PSMA5 PIN1 TSEN15 SHMT2 XRCC5 NOLC1 RPS4X TMEM59 HMGCL UGDH ECHS1 MGST3 HIBADH BCKDHB DARS2 POLR2L DUT IARS2 SSBP1 GPC4 MAGED2 AIF1L COMMD4 DPCD PMVK CPE PGRMC2 TES CLDND1 TECR RTL8C DMAC1 SNRPF MICOS13 MRPS14 BEX3 MRPL50 WARS1 NIPAL3 SEPTIN2 HIRIP3 MMUT HNRNPU SPCS2 SND1 DCDC2 PIGN BDH2 WDR19 ENSA RHBDD1 PRPF31 CHCHD7 PSPH DYNC1I2 JPT2 EAPP PREPL DLD S100A1 SH3D21 MAPRE1 EPRS1 PARL MRPL48 FSTL5 EDARADD MARS1 GET3 GARS1 MRPL58 NARS1 LARS1 TAFA4 CXORF56 KIFBP SARS2 FOR drug target network ERMP1 ATP6AP1 ATP6V1A ATP6AP2 TOR1AIP1 ATP6V1B2 ATP6V1G1 ATP6V0C ARPC3 ATP6V0B VPS35 VPS26A DPM3 ATP6V1E1 ATP6V1C1 ATP6V0D1 ARPC4 ACTR2 ACTR3 VPS29 SPEN PPID TMEM199 ATP6V1H COMMD3 WDR81 COMMD4 COMMD2 COMMD3-BMI1 AND CHST14 AND SNX27 SLTM AND PIK3C3/VPS34 AND ACP5 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 untreated v SARS-CoV-2 Calu-3 s1 4h polyA GSE148729 up F2RL1 IL1B BCL2L1 IL6 ATP13A3 XPO6 EGR1 BCAR1 SLC45A3 RRP9 DDX21 ASAP2 MACF1 ESRRA BAIAP2L1 YWHAG TLR4 AATF LYN GRPEL1 PMEPA1 BAG3 KLF6 FRMD6 BZW2 BAIAP2L2 QSOX2 SFN SDE2 PLAT PXN CXCL2 TGFB1 NPIPB3 EGFR CCDC86 FRMD8 PLEC CHD1 METTL8 SIAE SF1 MCL1 MYO10 KRT18 ITGA2 RGS2 HS3ST1 HES1 NT5E RAI14 SH3RF1 SERPINB2 MT-ND4L SLC2A1 GADD45A SEMA3A MT-ND4 CCND1 ITPK1 PTGER4 IL4R ZNF316 C15ORF39 DENND4B THBS1 SH3TC1 HBEGF MYADM GRK2 PSD4 RARA LTBR SLC1A5 ACLY ZYX PNP SDC4 AREG LDLR DDIT4 FKBP5 SPRY2 SMTN PPARGC1B DUSP7 FAM89A RAPH1 ARNTL2 MTHFD2 MPP6 ZNF574 CXCL8 ARL4C CTAGE9 AKAP12 KLF16 CDKN1A MYC MMP1 KLF13 CDV3 FGFR1 CISH PLAUR RDH13 GJB3 BCL9L SEMA4B IFFO2 PPP1R13L SLC7A5 EREG WNT7A SOX9 AXIN1 DKK1 FOXL1 TCF7 JAG1 MAP2K3 HIF1A DVL1 STK40 DHX34 NBEAL2 PHC2 PLEKHG3 ARHGAP27 MIDN DUSP2 CCL20 SYT12 LRP8 CXCL3 CD274 MLKL HAS3 TINAGL1 SOCS3 INHBA SLC25A22 FOSL1 F3 ANGPTL4 PLAU FST LRAT TSC22D1 ETS1 RPL28 IER2 LRFN4 IER3 IGFBP4 ACTG1 DUSP1 TGM2 HPCAL1 CDC42EP1 JUNB JUN VEGFA MAT2A ADAMTS15 AMMECR1L BMS1 DHX30 NDUFV3 FXYD5 ERRFI1 EHD1 NAB1 PHLDA1 FASN EFHD2 MSANTD4 NXF1 ARRDC4 KDM6B CREB5 KIFC3 MBP PPP1R15A B3GNT5 KBTBD8 TNFAIP3 SOCS2 CMIP CITED4 MUC5AC STC1 ADRA2A CALB2 TBC1D30 TOR4A DUSP6 LIF DUSP5 TIPARP SERTAD1 SERTAD2 CDC42EP3 PFKFB3 SH2B3 PPRC1 SOWAHC ZNF263 SRM TOMM34 DKC1 TMEM185B TNFRSF21 BZW1 NOL11 ETF1 GEMIN5 ARHGEF18 NKRF ODC1 ADORA2B FKBP4 POLR1C YTHDF1 SRSF7 ENC1 GSPT2 TPST2 YTHDF2 RPIA RASA1 FOXC2 URB2 GRAMD4 TATDN2 PAQR5 CSK SMOX MARS2 ZNF296 RNF139 SLC20A1 LONRF2 SLC26A2 ST3GAL1 WSB2 POGK XPOT EMP1 COA7 DUSP4 ZNF581 RHBDF2 NMUR2 CHSY1 AMPD2 R3HDM4 NAV1 MAST3 CDON DOK7 PTPRE TRIB1 CDC42EP2 BCAR3 PHLDA2 FHL2 OSGIN1 MBLAC2 DGKE SLC25A32 SEMA7A LAMA3 TNFRSF10D ADAM19 SLC17A9 CARD11 NR1D1 ADAMTS9 SPRY4 NWD2 GNA12 CAMSAP1 CDK9 BCR MAP4K4 CXCR4 OTUB2 IFNGR2 NFKB2 GNPNAT1 GRSF1 MOB3A STK10 SMURF1 UBE2F CMTM3 CDC42SE1 POLR3G URGCP TSPAN14 NIP7 USP36 EPHA2 LTV1 TXLNG WDR75 WDR43 TMCC1 RIOK1 CDCP1 MIOS KLHL21 KCNC4 PLK3 CHST3 FA2H TTLL12 MYEOV ASB1 FBRSL1 F8A1 FHL3 E2F4 NOP56 ENTPD6 ELK3 CCM2 AMOTL1 LETM1 CTPS1 SSH1 ABR ABLIM3 URB1 SLC25A44 HMGA2 PUM3 ITGA3 TNFRSF10A ABHD17C RPS6KA4 TNFRSF11A WDR1 SRF PER2 NPAS2 TGFA CLCN2 E2F3 PLXNA1 ELK1 ATP2C2 FERMT1 MTAP PPAN SYNJ2 TNFRSF10B PHF23 SCHIP1 ZACN CARD10 HK2 PGAM5 ZNF12 ZNF202 MTRR TRAF4 GPAT3 PRMT6 PPIF RBM38 FAM136A POLR3E ZNF639 UTP15 XPO5 DHX37 MRTO4 MYBBP1A RPUSD1 GEMIN4 RRS1 IPO4 RRP1B TXNRD3 SHC3 ANTXR2 ARHGEF2 ALKBH8 DCBLD2 UBASH3B KLHL18 NOP2 NOL6 GTPBP4 ARID3B AEN BICD2 BICD1 ZNF473 ABTB2 C18ORF25 DLC1 CXORF38 SLC25A37 TMEM201 ISG20L2 PWP2 RHOF MICAL2 MFSD2A TRIM47 FAM43A LRRC8C CAPRIN2 PDE3A ZMIZ1 TDG PDE10A CDR2 SACS GPATCH4 RRP15 A4GALT PDLIM4 DNMBP HPS6 MAK16 C11ORF24 POLR3D FAM86B1 ZNF598 UBE2O BCKDHA CAPN15 NOP16 POLR2J2 MPRIP SBF1 ICOSLG PDLIM7 ZNF408 ARHGAP26 PDP2 ARHGAP39 NIFK ALKBH2 ARMC5 CD3EAP IDH3A NSUN2 IMP4 NAT10 PUS1 POLR1B EIF4A3 EPN2 PDCD2L POLR1E RIN1 NOB1 GATAD2A KRI1 SNAPC4 ADO PAK1IP1 HAGHL MAP6D1 RTKN RUSC1 TRMT5 YRDC TRMT61A AMER1 SMIM11A MAP1LC3B2 FAM131A NOM1 EEF2KMT DDX31 MSANTD3-TMEFF1 INPP5F MTFMT RRP8 SYS1-DBNDD2 GCOM1 ZNF786 SLC25A19 RCL1 TIMM8A GTF2H2C_2 TNFSF12-TNFSF13 MLX E2F5 TMEM216 CHKB-CPT1B POM121C NPIPA7 BET1L 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 untreated v SARS-CoV-2 Calu-3 s1 4h polyA GSE148729 down UBB EEF1A1 FCGRT OS9 DPP4 CYP4F12 UBD FGF23 EPB41L2 DAAM1 ACE2 SLU7 IFITM1 NBR1 PRR15L ANXA2 HLA-B CENPF GGT1 TUBA1A OAS1 HLA-DRB1 HLA-C CYP2C18 STAT1 AGT CLIP4 B2M TSPAN8 EIF2AK2 ITM2A TRIM31 MAT2B ISG15 TKFC ARL14 MX1 PLEKHA7 ZBTB44 VAMP8 FAHD1 METTL7A MYO6 GSTZ1 RPS6KA5 PSMA2 CAV1 SERPING1 CEACAM6 GAREM1 MECOM CXCL6 TNFSF10 PIGR CFTR RARB IFI27 ERBB3 SLC40A1 FGFR2 GULP1 FDCSP COBLL1 ELF3 PBX1 NFIB KIAA1217 PNRC1 TRIM2 RICTOR MARCKS DSG2 FNIP2 TCP11L2 FAM214A SCIN ADGRL2 ADAM28 SSBP2 SORBS2 COX7C AGR2 ANK3 GCNT4 CHST9 ZBTB20 ARID5B VTCN1 GABRP CD24 TMBIM6 STMN1 GPR107 ACSS1 NUMA1 APOL1 GIGYF1 PIGK LEPROT BSDC1 APOL2 HLA-E TMED9 GRN NCSTN EXO1 TOP2A CDCA8 LMNB1 CCNB2 FZD2 NEK2 DEPDC1B HMMR ALCAM MCM2 KIF14 ASPM HADHB DLGAP5 BUB1 GPNMB CDK1 E2F1 KIFC1 CARD6 MYDGF KIF11 ANLN CEP55 MICU1 SPATS2L MKI67 LIPA SORT1 NCAPG ABCB1 IKZF2 GSTM1 CRIP2 AKR1C3 YPEL1 TCN1 PBXIP1 TFDP2 AUH RMND5A APLP2 PIK3IP1 MITF AR DSP ANXA8 MYH14 MEF2C RHOU TMSB4X WNT2B ODAM GABARAPL1 TNFRSF11B PRC1 CASP2 ELP4 RBM47 ULK1 RAB43 SMC2 CDC25C CFB MTFR2 TCF19 IQGAP3 NCAPD2 ECT2 NUSAP1 CENPI IFIT1 KIF20B SECTM1 HMGB2 NDC80 CENPE CTSS MOGAT1 OAS2 PSMB8 KIF18A HERC6 STAT2 STON1 GBP2 PARP9 SERPINA3 IFI35 PARP14 ATP13A4 CAV2 DPYSL2 PSME2 CYTH3 ATP6V0E1 UBL3 SH3BGRL ITM2C HLA-DQB1 BTG1 LYZ PDE5A NR1D2 PRRG3 IFI44L LAPTM4A TAPBP SLC12A2 MORF4L1 GLUL PAIP2 PDCD4 PTGR1 CD74 SRP14 RPS9 SAP30L CALR PSAP KLHDC3 MPC2 MXD4 TNS3 ANXA1 GNS HLA-DMA NDUFA4 SAT1 CTDSP2 NUCKS1 HAUS4 CD164 AGO4 SLC38A2 DEK LCA5L CLDN16 PRR16 HDAC9 ZNF292 CLSTN3 MAGT1 SNRPG PDZK1IP1 TM4SF4 HMGB3 SGCE RRM1 MPV17 ATP6V1C1 PJA2 HSP90B1 CRYZ ARL6IP5 CFL2 YPEL5 TIMP2 SERINC1 RFC4 FAM107B GMNN TMEM50A RB1CC1 DDB2 MXI1 TMEM245 HSD17B11 VAV3 SERINC5 GRB7 CUL4B TMEM47 METTL25 FOXO4 MNS1 PIR CREBRF MCU TMEM139 HMGCR KLHL24 ATAD2 IL1R1 PPM1K MUC20 CYP1B1 HLA-DMB CDKN2C FXYD2 IFI6 TESK2 CFI VPS41 LAMP3 DDX60 XRN1 SAMD9 GLG1 GLIS3 FBXO33 IGF1R LRRC31 FNIP1 LIMA1 KLHDC2 STYK1 PLSCR4 TRIM38 RABGAP1L BLNK TM7SF2 ADAM10 LPAR6 KANSL1L ARMCX1 BMF PIK3R3 ATF7IP DSC2 PLSCR1 PIK3C2G APBB1IP RNF5 UGT2B7 WIPI2 MLLT3 GBA RAB5B COPA CYLD SPP1 ALAD CALCOCO1 CITED2 ASAH1 C6ORF62 MTRF1 ABHD4 WDR44 TMEM123 MAP3K3 MDGA1 HDAC5 SYNE2 KLHDC7A KLC4 ZFYVE26 BCL6 NEXN ALPK1 TPP1 PSEN1 HBP1 DST TBC1D9 GMPPA HLA-DRB3 OCLN MCCC1 HNF1B MTUS1 MMP7 INSIG2 UGT1A10 SEMA6A JMJD1C SLC44A4 HIP1R CDK19 SHROOM3 CHD6 SLC2A12 AMOT CYP3A5 DTYMK CCNG2 PCM1 TRIQK CHD2 DAPK1 ZFYVE1 ATG14 EPG5 ERBIN TFPI GOLPH3L APAF1 SIRT2 ABTB1 WDR48 TBC1D15 GJB1 BAAT LMO4 FUBP1 ATF2 CCNG1 TACC1 TMEM59 SDCBP OXR1 ACSF2 KRT23 NYNRIN PALMD HECA FBXO2 TCAF1 MAGED2 TIAM2 ARHGEF28 CAPS PLEKHB1 ELP6 KIF3C TENM3 DSC3 DCUN1D1 FAT4 ZNF608 GPSM2 PGRMC2 NHLRC3 NTN4 LGR4 ELF1 RAB27B ARPP19 CDC42SE2 DCAF11 RNF103 PPFIBP2 WBP1 ARID4B MGAM2 MACROD2 FBXL20 CTAGE15 PPM1L PSORS1C1 IQCK PPP2R3A PALM3 SWAP70 NUDT7 SND1 DCDC2 PCMTD1 MAN1A1 PIGN PLK4 BDH2 BROX WDR19 ENSA SESTD1 SHTN1 DSN1 ZNF738 LCMT2 PPP1R3E SMIM14 PKIA PNPLA8 FCHO2 PLEKHA3 GPRC5B NPAT TMEM87A C2CD5 TCEA3 CDKL5 SYT15 CWF19L2 BRD8 NME1-NME2 ZNF33A CHURC1-FNTB POC1B-GALNT4 DCAF6 CCDC150 CCDC125 GOLGA6L4 CRBN ZNF519 TEN1-CDK3 PCDHGB7 PLEKHM3 C2ORF68 SMIM11B SPDYE2 ARHGAP11B DCAF8 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 mock v SARS-CoV-2 Calu-3 s1 4h polyA GSE148729 up IL1B IL6 EGR1 IL1A ASAP2 GOLGA3 NF2 FURIN NEDD9 RUNX1 PMEPA1 KLF6 RNF41 HOOK3 ZYG11B BRD2 DNASE1 RELA CRK PXN PI4KB IFNB1 NPIPB3 EGFR FRMD8 PLEC CHD1 SIAE CPT1A MCL1 NPHP3 ITGA2 KLF5 HS3ST1 KRT17 HES1 MT-ND5 NT5E SH3RF1 GATAD2B USF3 MARCKS ZNF460 MT-ND4L TET2 SLC2A1 GADD45A MT-ND4 PLEKHG1 CEP170 TAB2 NACC1 PIEZO1 ZNF316 THBS1 SH3TC1 INPPL1 MICAL1 HBEGF PTK2B ZDHHC7 MYADM CIC RARA TRIM65 RHOB TMEM106A DDIT4 SPRY2 EPHB2 TEX2 RAPH1 ARNTL2 RASGEF1B ZNF574 SEMA4C LRFN3 ARL4C TPM2 CTAGE9 GATA3 AKAP12 NUAK1 EFNA5 CDKN1A MYC TUFT1 ZFP36L1 ZFP36L2 GADD45B EP400 FGFR1 PLAUR GJB3 BCL9L CCDC120 GRHL2 RARG PPP1R13L CAMSAP3 KRT80 FAM83G WNT7A NLK SOX9 DKK1 FOXL1 TCF7 JAG1 MAFK DVL1 ZNF628 DHX34 KDM4B SOWAHB TMEM63B PHC2 FBRS MIDN IFIT3 CD274 HAS3 SOCS3 INHBA FOSL1 F3 ANGPTL4 FST LRAT TSC22D1 AHR ETS1 ZFP36 IER2 LRFN4 IER3 IGFBP4 DUSP1 JUNB PXDC1 JUN VEGFA ADAMTS15 AMMECR1L GABARAP EPC2 ITPRIPL2 NDUFV3 ERRFI1 AGO1 PHLDA1 MSANTD4 RFTN1 DMD KDM6B PPP1R15A SYNGAP1 TCERG1 B3GNT5 C21ORF91 DCUN1D3 TNFAIP3 ZNF267 ZNF841 CMIP FOXK1 AMOTL2 DUSP6 PPP1R15B LIF KLHL15 DUSP5 FEM1B ZIC2 CSRNP1 BAMBI BHLHE40 TAF1D TSC22D2 SERTAD2 CDC42EP3 PFKFB3 KANSL1 FOSB SOWAHC MSL2 PPP1R18 SPIN2A AMIGO2 ARHGEF18 NKRF GNA13 ZMAT3 KLF7 ENC1 MN1 COL7A1 MAP1B TBL1XR1 TAF7 GSPT2 PRR15 TPST2 MRGBP MAML1 SCAF8 CLIP2 C3ORF52 CDH6 SIK1 RASA1 FOXC2 ABL2 URB2 GRAMD4 RNFT2 ZCCHC2 NOXA1 LENG1 PELI2 CFAP44 SLC20A1 DCPS SLC26A2 ZNF623 SHPRH ST3GAL1 PDPK1 CRKL SMURF2 SRGAP2C FEM1C PPP1R10 MIA2 CPEB2 TICAM1 DUSP4 ZNF581 NICN1 RBMS2 DYRK1A NAV1 MAST3 CDON NBPF10 PTPRE TRIB1 CDC42EP2 BCAR3 PHLDA2 TRIM16L SEMA7A TNFRSF10D ITGB6 ADAM19 SLC17A9 NR1D1 SPRY4 ETV3 NUMBL RHOT1 CAMSAP1 DOK3 MDM4 CDK6 SIM2 PRKAB1 TBC1D20 IFITM10 TRIM11 SMURF1 RAP2C UBE2F NXN KCNJ15 CDC42SE1 URGCP IP6K2 IRF2BP1 EPHA2 RASSF1 RBBP6 TMCC1 DMPK HMGXB3 KLHL21 KCNC4 PPP1R3B CHST3 PHLDB1 COL27A1 NCOR2 ASB1 POLR2A FBRSL1 NIPAL4 RHOBTB2 FHL3 PLXND1 ELK3 CHFR ABLIM3 SASH1 SLC25A44 TSSC4 MEX3C HMGA2 PHLDB3 APEX2 DTX2 ZFHX3 E2F3 SLC22A3 PLEKHH1 KRAS ASXL1 FERMT1 RING1 CBL PDGFB SYNJ2 DYRK2 PHF23 AMBRA1 SCHIP1 NUTM2D SPDYE6 CARD10 FBXW7 ZSCAN32 SETDB2 ZNF202 ZNF800 RPP38 TGIF1 WSB1 SOX4 DHX37 CASP10 ARHGEF1 NFKBIB SUSD6 DIO3 ANTXR2 ARHGEF2 ALKBH8 DCBLD2 UBASH3B C22ORF23 GPC4 POGZ KLHL18 ZC3H4 NFRKB GMEB2 CSRNP2 QKI ARID3B RUSC2 AEN BICD2 BICD1 ZFX ABTB2 ZNF140 C18ORF25 DLC1 SKIL FSTL3 RHOF MICAL2 CSNK1E DDX28 TRIM47 MYSM1 DIP2B ACVR1 LCA5 ANKRD50 ZXDA ZNF579 FRMD5 ZNF697 ZNF277 RASGRF2 CAPRIN2 INTS5 PDE3A ZMIZ1 DSTYK C12ORF49 SVIL CDR2 PDZD8 CDK13 PCNX4 SLTM GRAMD1A PDLIM4 C16ORF72 HPS6 FAM86B1 BCKDHA PHF13 EVI5 NCKAP5L MFSD4B RGMB ZBTB7A MCM3AP PIAS2 OTUD4 RAPGEF6 RAI1 SNX33 CAPN15 RASAL1 ZNF264 ZSWIM3 MPRIP RBM48 IRF2BP2 EAF1 KIAA0586 PDP2 PWWP2A INAFM1 GTF2A1 ARMC5 PLLP CD3EAP KDM7A CLP1 ZNF155 POLL EPN2 POM121 POLR1E RIN1 FAM76B ZDHHC21 GATAD2A PPP1R26 ADO FAM135A TRAF3IP1 FBXL14 WDR47 ZC3H12B ZNF134 DLGAP4 ATXN7 AQP7 RFTN2 SNX27 AGAP9 DUSP18 TRMT5 YRDC RNF215 ZNF559-ZNF177 RNF169 MAP1LC3B2 MSANTD3-TMEFF1 SYS1-DBNDD2 GTF2H2C_2 TNFSF12-TNFSF13 AMY2B PCDHGA12 KRBOX4 NPIPB11 CTAGE8 TMEM189-UBE2V1 HSPE1-MOB4 HEMK1 DPH1 FKRP KBTBD11-OT1 RGPD6 FBXW10 EYS ZNF343 ZNF625-ZNF20 C6ORF89 ZNF675 ZNF619 NPIPB5 ALDH3B2 CNBD2 KCNAB3 FBXO46 MSH5-SAPCD1 MVB12B ZNF174 FAM160A2 CTRL FOXD2 CHN1 PCGF3 AVL9 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 mock v SARS-CoV-2 Calu-3 s1 4h polyA GSE148729 down GLA UBB DCTPP1 SUMO1 UBL5 TIMM8B EEF1A1 FCGRT OS9 CYP4F12 SUMO2 GHITM UBD FGF23 YWHAQ EPB41L2 ETFA KPNA2 SLC1A1 ACE2 PPT1 TMPRSS4 CYB5B TMEM97 DDX1 SCCPDH SLC30A9 ANXA2 HLA-B ADAM9 GGT1 TUBA1A CALM1 PSMD4 OAS1 HLA-DRB1 HLA-C CYP2C18 NUTF2 STAT1 AGT CANX B2M TSPAN8 ST6GALNAC1 NDUFB9 USH1C HSBP1 POLA2 ITM2A PHB NEDD8 MAT2B ISG15 MX1 SMO MDH1 GLO1 PSMB1 SPTLC1 VAMP8 COX15 FAHD1 NDUFB6 GSTZ1 ALDH1A3 SAC3D1 ADK PSMA2 BTF3 SERPING1 RPS26 RPL35A CXCL6 TNFSF10 PIGR RPL9 ASS1 CFTR IFI27 GPX2 TSPAN6 NME5 RPL24 RPS25 ADAM28 COX7C AGR2 COPS9 VTCN1 GABRP CD24 STT3A TMBIM6 PDIA6 STMN1 GPR107 UQCRC1 PIGK CYBA RGS12 HLA-E TMED9 GRN TOP2A ZWINT CDCA8 CAPG LMNB1 SEC11A ALCAM MCM2 SLC39A11 GPNMB CDK1 COMMD9 PRDX1 MCM10 FAM72C GSTO1 MYDGF NME1 RMI1 ANLN ACO2 KIF23 IFI27L2 PRDX3 MKI67 LIPA PRELID1 PSMB7 AKR1C3 TCN1 PBXIP1 IGFBP3 SLC2A6 SDR16C5 APLP2 CYCS ZBTB42 CYB561 PROM2 WLS CLU TMSB4X NUCB2 TNFRSF11B CD63 PRC1 PSMA3 PDLIM5 CENPN SMC2 CDC25C CENPA CFB MTFR2 ESCO2 FANCI ASF1B GATM MCM5 ZWILCH HMGB2 VAV1 NDC80 CTSS RAD51AP1 KIF18A DHFR HERC6 RNASE4 CLDN2 SERPINA3 MITD1 PLAU ATP13A4 SLC3A1 CD59 PSME2 SPTSSA ID3 EIF2S3 ATP6V0E1 CLDN18 MRFAP1 MORF4L2 CHCHD2 FABP5 RPS19 HLA-DQB1 LYZ SNRPD2 NACA ACAT2 PPIB PRRG3 PSMC2 DNAJC8 ISCU LAPTM4A SLC12A2 MORF4L1 PAIP2 CETN2 RPL18 CD74 SRP14 RPS9 OAZ1 NDUFA2 IFI30 CALR PSAP AQP1 MPC2 NDUFA1 RAB11A RPL36AL NDUFA6 ANXA1 LRG1 HLA-DMA NDUFA4 ARL1 SAT1 NDUFV2 NOP10 POLR2K NDUFC2 DBI PPIC SEC61G OAT PGRMC1 TMED2 MIEN1 CACYBP RBM8A DEK OLFM4 TMEM213 TSPAN31 ANP32A MAGT1 SNRPG PDZK1IP1 TM4SF4 HAT1 HMGB3 SUPT16H PSMA4 CDC123 RRM1 EMC4 ATP6V1E1 ATP6V1C1 CHMP5 M6PR NDUFAB1 HSP90B1 MRPL27 CRYZ ARL6IP5 MIF MRPS33 RNASEH2A ATP6V1D AP1S1 PARK7 RPA2 PSMB3 TTC1 ZMAT2 NOP58 PCNA PSMC1 BCAS2 NOSIP TIMP2 HDAC1 CTSO NDUFA12 PCMT1 SERINC1 RFC4 FAM107B PSMD14 SLC39A10 GMNN DCTN6 AKR1B1 GLRX2 ERH UBA3 HSPE1 NDUFA9 EIF2D RAB1B ETFB RPL34 LDHB RNF20 IER3IP1 HSD17B11 SKA2 ITIH2 ZNF512 AKR1B10 IK HMGCR SQLE ZMPSTE24 BCHE MCM6 MRPL47 RBP5 FEN1 MUC20 CTSE TFRC HLA-DMB LBR CTSV FAM111B CFI VPS41 IFT74 GPATCH1 APOBEC3B MLEC PCYOX1 PKIB LIMA1 UGT1A6 KLHDC2 SP140L TM7SF2 MSRB1 ALDH2 CLIC1 BLVRB SERPINB1 CALM2 ADAM10 ACTR2 SESN1 RARRES1 PRDX2 PGK1 IKBKE COPS4 POP4 EXOSC1 IDI1 ARL2 GBA PPP5C UGP2 COPA FKBP3 AIP NECAP2 SPP1 APIP HPF1 CREB3 AIG1 ASAH1 CLTC ARF4 ACOT1 C4ORF3 CCDC115 GGCT COMMD10 DCAF13 TSPAN1 RAC3 PTER PDIA3 CBWD2 SGK2 ADI1 BCL6 ANKRD22 TPP1 RTN3 PSEN1 HBP1 NDUFA11 GMPPA IFT43 HLA-DRB3 FDFT1 SMARCA2 CST6 MMP7 INSIG2 UGT1A10 SERPINA5 SLC44A4 TRIQK IQCJ-SCHIP1 MRPS22 IVD UGT1A1 SIRT2 SLCO1B3 BCL2L2-PABPN1 RFC1 PARP4 GJB1 BAAT CALU SGPP1 CCNG1 LIN9 PSMA5 THOC3 TMEM59 HMGCL SDCBP NDUFS5 CYB5R1 HNMT MRPL23 KRT23 PALMD TIMMDC1 ADGRF1 HACD3 DUT CSN3 MAGED2 IL17RB CAPS NSDHL PLEKHB1 NTN4 GALC QPCT IFRD1 COMMD2 CCDC167 DCAF11 C17ORF49 MAPRE2 LSM3 IDNK BEX3 PRRX1 TMCO1 TMEM9 CNIH4 CTAGE15 ERGIC2 HIGD1A IQCK SPCS2 SND1 PLK4 BDH2 SNAP23 ZNF738 AAMDC RHBDD1 MRPS10 IPO11 CADM1 GNG7 TMEM132A CTDSPL2 DLD TCEA3 ACAD10 DRG1 PARL MRPL48 NSMCE2 GATC NME1-NME2 POC1B-GALNT4 CCDC125 GOLGA6L4 PCDHGB7 EIF4EBP3 ATXN7L1 PNMT CNOT7 CBWD3 ZNF93 DNAJC25-GNG10 LPAR4 ZNF20 BLOC1S5-TXNDC5 ZNF425 RGPD5 MSH5 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 24h from GSE148729 mock v SARS-CoV-2 Calu-3 s1 24h polyA GSE148729 up NKX3-1 RSRC2 SEC16B BIRC3 IL6 GDF15 CCL5 EGR1 UBD NMI TNF DDX58 IL1A CXCL10 IFITM3 CYP2J2 IFITM1 HLA-B NEDD9 LAP3 ZNF274 JAK2 KLF6 NPTX1 IFNL3 NFKB1 BRD2 RBCK1 SNIP1 OAS1 PTX3 HLA-DRB1 HLA-C STAT1 TRIM25 HLA-A IFITM2 SRPK2 B2M MYCBP2 EIF2AK2 IL22RA1 HERPUD1 APOBEC3G OASL TRIM31 MOV10 CXCL2 IFNB1 ISG15 ZNF503 NUB1 ARL14 STC2 MX1 MYD88 WFDC5 ZC3H12C CD55 MCL1 MT2A TNFSF10 CEBPD IFI27 KRT17 EXT1 ZEB2 NT5E KIAA1217 PNRC1 CFH RICTOR SERPINB2 HSPB8 GADD45A RND3 ANKRD33B SEMA3A ISG20 ZBTB20 ZNF462 CMTR1 UNC93B1 TNFAIP2 PTGER4 USF1 KSR1 PARP10 LGALS3BP HBEGF APOL1 TYMP BST2 SLC15A3 ITGAM APOL2 HLA-E SDC4 AREG IFI44 MAFG SLC1A3 EPSTI1 SPRY2 GRB10 APOL4 BATF2 RASGEF1B CXCL8 PTGS2 NCALD B4GALT5 CDKN1A BMP2 BDNF SNPH PLAUR FOXO1 EREG NAV2 ATF3 FZD4 FOSL2 CEBPB SLC12A7 HELZ2 NUAK2 OGFR RSAD2 OAS3 IDO1 IL10RA IRF7 CFB ZBP1 NLRC5 GBP5 TNFRSF9 TAP1 CCL20 IFIT1 SECTM1 CTSS MASTL RYR2 CYP1A1 IFIT3 RTP4 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 PSMB8 CD274 APOL6 GBP4 DHX58 USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 MLKL CPXM1 LGMN STAT2 PML PLEKHA4 SOCS3 NFKBIE ADAR NAMPT NT5C3A PARP9 PARP12 SAMD9L GCH1 HSH2D ADM FAP IL4I1 INHBA RNF213 IFI35 PARP14 FOSL1 HAS2 SOCS1 TRAFD1 SAMHD1 UBE2L6 TLR3 UBA7 FST SP110 CSF3 ACKR4 SCN3A PSME1 EHD4 PSME2 KLF4 ZFP36 LY6E IGFBP4 IRF1 PSMB10 RASGRP3 DUSP1 TGM2 TXNIP ICAM1 DTX3L NFKBIA ID3 IRF9 PSMB9 GBP3 JUN HLA-DQB1 IFI44L SERPINB9 TAPBP HIPK3 ARRDC3 CD74 IFI30 CCNL1 CYP2B6 THEMIS2 SAT1 ARRDC4 CREB5 ZC3H12A DUSP8 LTA TRAF1 NR4A3 IFNL1 HSPA6 PPP1R15A CSF1 TRIM22 ATP4A PTGER2 B3GNT5 TNFAIP3 HDAC9 ZNF267 ZNF292 PLA2G4C GIMAP2 BBC3 PPP1R15B NEURL3 LIF FLRT3 DUSP5 IER5 TIPARP CSRNP1 SERTAD1 CHAC1 MAFF NFKBIZ TSC22D2 ZNFX1 PNPT1 RLF MXD1 RPS6KC1 ZNF317 DNAJB4 GPBP1 DUSP10 TNFSF15 ITPKC HIVEP2 C15ORF48 USP43 GNB4 CD47 NEDD1 KRTAP4-6 ODF3B REL ABL2 TAP2 CIITA ASNS SLFN5 CASP1 PPM1K IL15RA ZCCHC2 GCA TRIM21 TAPBPL TRIM56 ZC3HAV1 TRIM5 TDRD7 TRIM14 PCGF5 TRIM69 MAP3K8 RIPK2 ACTN2 IKZF3 IRAK2 HSCB PRKD2 HLA-DMB CXCL11 IFI6 GSDMB IL32 PER1 IFNL2 LAMP3 DDX60 DIRAS3 SLC25A28 RNF19B LGALS9 TNFSF13B XRN1 SP100 BCL10 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 ADRB2 SAMD9 GBP1 CASP7 SPAG9 MB21D2 HES4 ETS2 CEACAM1 CDK17 RELB RCAN1 ETV7 GPT2 BTN3A3 GMPR BAZ1A NFE2L3 PMAIP1 CX3CL1 HLA-DRA ARL5B PATL1 NAPA ERAP2 SP140L MDK APOL3 N4BP1 SMCHD1 TMEM62 BTN3A1 C1S MOB3C HLA-DPA1 TRIM38 FAS PARP8 SH3KBP1 BLZF1 FMR1 BTN3A2 BTC PARP3 PHACTR4 PIK3AP1 OPTN CFLAR RNF149 TRIM26 CASP8 GLCCI1 PIK3R3 SESN2 TRIB1 BACH2 SEMA7A BACH1 KCNN1 IGF2 ADAM8 PLSCR1 SAA2 CD68 NCOA7 ETV3 CDC14A MMD2 ANGPT2 IFNA7 C4A CCL3 TNIP1 CARD16 DICER1 MAP4K4 XBP1 PELI1 NFKB2 NEDD4 SP140 STK10 OTUD1 CYLD SMURF1 CITED2 EPHA4 ASAP1 ERAP1 ARHGAP24 TEP1 SYNE1 HAPLN3 PODXL FA2H DAPP1 PLXNA2 HLA-DOB HLA-DRB3 TNFRSF10A LRP2 ZBED5 DNPEP DUOX1 KDM6A KMT2C COL11A2 DAB2IP CHD2 TNFRSF10B AMBRA1 NOD1 RAB24 FLT3LG BTN2A2 GTPBP1 LPA CD2AP COL16A1 SPATA2 DCP1A FNDC3A PDZD2 ARHGEF28 UHRF1BP1 AFAP1 REV3L ENDOD1 UBN2 ZNF697 DNAH17 CNP FRS2 BAZ2B NOCT RGMB KLHL29 CPEB3 ARID4B PPP4R4 MED12L TLK2 CPEB4 ARAP2 SIPA1L2 DCLRE1C MFSD14A DND1 CFAP57 TRPC4 RANBP3L ST3GAL2 SYDE1 KCNV1 INO80D SHROOM2 CXORF49 NKAIN1 TTC9B CXXC4 CSAG3 CXORF49B 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 24h from GSE148729 mock v SARS-CoV-2 Calu-3 s1 24h polyA GSE148729 down EEF1A1 ERMP1 MAPK3 CAPN5 MALL ERGIC1 SUN2 PRKACA ITGB1 KPNA2 NPC2 RBL2 MYO1D CACNA1D TPM4 PPT1 RNPEP NPC1L1 ANXA2 NDRG1 VILL CENPF PMEPA1 GGT1 AP2M1 CIT TUBA1A ANXA11 FAM162A PLS1 ANXA13 CTSD TSPAN8 LGALS4 ITM2A HS2ST1 PRKAR2A CAT REEP6 TOP2B MDH1 GLO1 CLDN10 ADH5 SCP2 MPP7 FGFR4 PTTG1IP METTL7A UNC119B IFT122 CAV1 RNF128 VKORC1 NBEA VEPH1 SDC1 TGFB2 AK4 NT5DC2 PERP CFTR ARL3 REPS2 RAB40B UPK1B SH3BGRL2 TSPAN6 METTL7B SPAG16 PLCE1 STEAP4 BCAS1 SORBS2 CHST9 EMP2 SLC25A23 VTCN1 CD24 TAGLN2 ATP1A1 TMBIM6 STMN1 GPR107 TGOLN2 TGFBI ITGB5 LRP1 CMTM6 ABHD2 PLK1 DHCR24 TOP2A LMNB1 CCNB2 C5 GTSE1 CDKN3 UBE2C FZD2 NEK2 NUF2 HMMR KIAA0930 ALCAM BUB1B ASPM HADHB AURKA DLGAP5 FADS1 BIRC5 KIF4A SAPCD2 ROGDI PRR11 TPX2 CCNB1 CEP55 IDH1 CDCA3 CDC20 KIF23 PRDX3 PAPSS1 LDHA SORT1 KIF20A SCD NCAPG ABCB1 PDGFD CRIP2 AKR1C3 PTPRS TCN1 PBXIP1 TRAM1 ABCC4 PIK3IP1 CYP24A1 IMPA2 CELSR1 ITGB4 SCNN1A SSH3 PROM2 HACD2 TPD52L1 EVPL RAB4A ODAM CD63 PSRC1 PTPRU TRIOBP SLC16A5 TBL1X SMC2 ARHGAP11A MXD3 CYFIP2 IQGAP3 PARPBP NCAPD2 NUSAP1 CENPI RACGAP1 SPC25 DEPDC1 SYT12 EFCAB11 SNCA DHFR SERPINA3 EPHX1 SLC3A1 TTYH3 CAV2 DPYSL2 LASP1 TNNC1 THRA HMGCS1 PTPRB RPL3 RPLP0 LYZ CTSH PDE5A ACAT2 MYH10 SLC12A2 LTBP3 EID1 HCFC1R1 VIM PDCD4 TOMM20 HADH NDUFA2 PSAP MPC2 MXD4 DSTN MYLK GNS GM2A EEF1G FASN MEGF8 DBI OAT PGRMC1 TMEM256 BNIP3L OLFM4 ADRA2A PFKFB3 ATRAID MAGT1 TM4SF4 HMGB3 CRYZ ARL6IP5 POLD2 PTTG1 HMGB1 GPR160 MAGED1 AHCY PSMD10 LSM7 TMEM230 ANP32E GNG12 CKLF PAM SLC44A3 MGLL HTATSF1 SLC39A10 CXXC5 PPP3CA ETFB SUCLG2 VAV3 SERINC5 MNS1 AKR1B10 SRI INSIG1 MSMO1 HMGCR SQLE CD46 CDCA7 ITGAV MCM6 DNAAF3 MVD TNNT1 SAMD13 TNFAIP8L1 TFRC PTMS FGFR3 CYS1 PCSK9 CTSV SYT16 CFI MBNL3 MAN2A1 SUMF1 FAM149A ACP6 SLC26A2 IDH2 SEMA3E GALNT12 AHNAK2 NEB TRHDE TMEM237 MLEC CBX5 KCTD12 KIAA0100 TTC3 APPL1 PCYOX1 DNAJC22 NDRG3 UCP2 PAPSS2 IGF1R PRKACB VAT1 BRI3BP CA9 TM7SF2 CMTM4 PYGL CHP1 ACTR2 PDK1 NEK6 FADS2 DNM1 CTNND2 ITGB6 ROR1 DPYSL3 STK32A KLK6 RARRES1 CCDC34 PGK1 COX11 IDI1 UGT2B7 ROS1 SC5D TSN FARSB SEPHS1 EEF1A2 PRKCA COX16 COX20 SPP1 GALNT1 NNT TPM1 ASAH1 AHNAK CCDC115 ALDH3B1 ACAA2 ANXA4 CHMP3 COA3 KRT10 C11ORF80 HNRNPUL2 LRRC20 DYNC2H1 STAU2 MEGF6 KCNC4 MATN2 MAZ ATP9A LSS MSI2 G6PD RTN3 PLXND1 ILVBL FARP1 UROD TBC1D9 TBCD FDPS SH3YL1 FDFT1 SMARCA2 SPOCK2 ACSM3 MMP7 SREBF2 UGT1A10 SEMA4G ACACA SERPINA5 VWA1 SLC44A4 HOMER2 PTPRF WNK2 SRD5A3 DTYMK CBX7 MBOAT2 TRPV4 NOTCH3 MYO1C ABCA3 TLR5 CYP27A1 PRKDC NCAM1 GSTM3 DNAH5 ABCA2 CYP51A1 GCSH SERPINA4 GJB1 ACSS2 LMO4 LAPTM4B XRCC5 GNPAT TMEM59 HNMT ACSF2 CTDSPL PALMD ANXA9 TMEM19 TPGS2 VANGL1 DARS2 ALDH7A1 HACD3 IARS2 CSN3 GPC4 NIPSNAP1 EIF3L FAM168B AIF1L CAPS KIF12 DHCR7 KCNMB4 UBE2E3 CTXN1 SAMD1 MMAB DSEL PLEKHB1 PCYT2 SLC25A1 MAOB GALNT10 EBP SYNGR1 PIF1 PGAP3 CARHSP1 DSC3 PXMP4 TBC1D5 MAN1A2 LANCL1 CPD GPSM2 C11ORF54 HGSNAT BICC1 VGLL1 SPNS2 ECH1 DCAF11 GOLIM4 HSDL2 KCNQ3 FAM20B CDK14 WBP1 NUDT3 MGAM2 ARSD SVIP RASAL1 NIPAL3 SGO2 CBX6 PPM1L ATP11A CHD3 APPL2 CACNG4 FAM168A ERLIN2 CD99L2 KIF1C OXCT1 ESYT1 FRAS1 PHKB ANO10 DAG1 PIGN SMARCC1 MOB3B VOPP1 TMEM106C TNFSF12-TNFSF13 CNTNAP3B ARHGAP33 SDK1 NDC1 HSD17B8 PITPNM3 TCEA2 CEP70 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 mock v SARS-CoV-2 Calu-3 s2 4h polyA GSE148729 up CEP350 RB1 GCC2 CNTRL APC EGR1 DDX5 GCC1 MACF1 BRAF CENPF RUNX1 KLF6 SMAD3 COL4A2 FN1 CSNK2A2 FOXA1 MUC3A TRIM31 PLB1 AKAP9 FRMD4B ZNF318 ING3 ANO6 MAP3K1 CHD1 RAB11FIP2 NR3C1 USP34 PLEKHA7 LIFR MYO6 RASEF MECOM ZNF532 RARB TRPS1 DUSP16 SYTL2 YAP1 PATJ COBLL1 NFAT5 LRIG3 TEAD1 GATAD2B RALGPS2 LURAP1L LMO7 PEAK1 FREM2 TRIM2 RICTOR QSER1 FNIP2 MT-ND4L BDP1 TJP1 MT-ATP6 ABLIM1 THBS1 TMC8 GIGYF1 PLEKHO2 KIF18B BUB1B STARD13 UACA ASPM SPRY2 CDKN2B STIL UNC13B TOPORS CTAGE9 ATR ZFP36L1 KLF10 CNOT6 ZFP36L2 TRAK1 PIK3CA EP400 MAPK8 CSNK1G1 NCOA3 DSP HEATR6 CAMSAP3 ZNF217 WNT9A SOX9 BMP2K NAV2 WDR37 MAP3K4 OTX1 TBC1D8 ATAT1 PHF12 PCNX1 KIF13B RERE CREBBP TAB3 BRPF3 ULK1 CASZ1 MIDN SMC2 C1ORF112 KIF20B MAB21L3 CCDC18 VCAN RNF213 ATP13A4 AHR BMPR2 ZFP36 EPAS1 TXNIP PTPRB RAPGEF2 AMMECR1L HIPK3 TP53INP1 ITPRIPL2 ERRFI1 CCNL1 WNK1 TNS3 MYLIP SLC38A2 ARRDC4 EGR2 GPRIN3 TCERG1 KBTBD8 ZNF841 PPP1R15B FEM1B YOD1 BHLHE40 SERTAD2 FOXO3 BTAF1 FOSB HAVCR1 RLF MXD1 AFTPH VAV3 KLF7 ZNF322 OGT NUFIP2 PURB SETD2 MAML1 KLF3 MAP2 SCAF8 PSD3 MST1 ZCCHC2 ETV6 PIKFYVE CCDC15 CYP1B1 GOLGA8B GOLGA8A SYT16 CFAP44 CCDC68 SMG1 TPR NHS GPATCH1 NBPF11 SHPRH ZBTB6 XRN1 CCNT1 CBX5 SECISBP2L TTC3 GLIS3 NIPBL KDM5A CRKL PPP1R9A ASH1L FEM1C TP53BP2 HERC1 BOD1L1 PPP1R10 THOC2 ONECUT2 RSF1 RFX7 SRRM2 SLC25A36 ETS2 AFF4 FBXW11 HDX SLC28A3 PLSCR4 IRS1 SON DYRK1A ST6GAL1 BTBD8 BMF ATF7IP NBPF9 RTN4RL2 DSC2 COL12A1 NR1D1 ETV3 TRAF6 SARM1 RANBP2 CTCF NPC1 EIF2AK4 DPP8 DICER1 CDK6 SPEN PIAS1 NR2C2 ZBTB38 NUP153 ZMYM4 CGGBP1 ZC3H11A ZNF324 PARP6 ZFHX2 PDP1 DYNC2H1 TXLNG CCNT2 ZMYM2 PPP1R3B FAT1 ENG EML5 AKAP13 SYNE2 AMH ATP9A TET3 BCL6 TANC1 BRD9 TAF1 VPS13D HBP1 MICAL3 DST NISCH PPP1R12A SREK1 ANKRD17 PBRM1 HNF1B KLKB1 SYDE2 NPEPPS ZBED4 GDF9 ARHGAP5 LMTK2 E2F3 USP9X SEMA6A NCOA2 KMT2A MAGI1 TBPL2 KMT2C SENP7 JMJD1C PNPLA7 ARHGAP32 C9ORF152 CHD6 NF1 KRAS CBL AMOT SMC4 SETD5 PIK3C2A TTC30A CHD2 ARHGEF38 NPIPB4 BCL2L11 DAPK1 ATG13 WDFY3 ERBIN UBR5 UBR2 MT-ATP8 APAF1 SESN3 SMCR8 FGD4 PLD1 RSC1A1 SETX RALGAPB FBXO11 PEAR1 NAA15 CBLB CCDC88A BIRC6 TACC1 PRDM4 LATS1 ZNF24 SUSD6 OXR1 VANGL1 POGZ ZC3H4 QKI SNX19 RNF146 CNOT4 GGNBP2 RHOBTB1 RASAL2 ITSN2 TNKS2 INO80 FGD6 C20ORF194 BICD1 MED13L KDM2A MID1 DLC1 ARHGEF28 UHRF1BP1 HIVEP1 RIBC2 DIP2B REV3L ACVR1 ANKRD50 PTAR1 TMEM131 CCDC6 ZNF608 CCDC14 CEP120 KIAA0319 CAPRIN2 ANKRD28 JMY ARFGEF2 ARHGAP21 FRS2 ICE1 PTPRK ELF1 CMTR2 ASXL2 MED13 BTBD3 RASA2 CAMSAP2 KAT6A PDZD8 SACS KIAA0232 AGAP6 TNRC6A RAB27B PKHD1 WAPL TRIO RPRD2 RALGAPA1 LCOR DNMBP PHF21A PCF11 FBXO38 VPS13A GOPC ZNF248 SOS1 MCM3AP REST EMSY PALLD ZNF106 FRYL NBPF20 PRR14L ZKSCAN2 PPM1L ATP11A FAM168A PALM3 EHD3 BAZ2A WDR26 PRPF4B ZFC3H1 LUC7L2 CEP95 CHD9 FRAS1 PLK4 C18ORF54 SESTD1 RFX2 NKTR PABPC1L BRWD3 KIAA1109 PHLPP1 MUC6 ZNF615 CHD7 PRKCQ AFF1 FAM53C ZNF260 DENND1B ZBTB41 FAM160B1 OSBPL8 ZNF518A ZNF251 ATL2 TAOK1 FAM135A ADNP DNAJC13 USP47 KLHL9 C2CD5 ZNF638 ATXN7 PKN2 ANKRD20A1 NUTM2B MOSPD2 LRRC37A3 AGAP4 BRD8 ZNF559-ZNF177 SMIM11A SYS1-DBNDD2 ZNF33A C16ORF70 RANBP17 TRIM33 ZFP62 NEPRO OFD1 SRCIN1 GRIP1 PCDHB3 NPHP4 ARFGEF1 MAGED4B NBPF12 INTS6L ZNF420 TTC30B OSBPL3 PRICKLE4 IQSEC1 AL592183.1 RNASEK-C17ORF49 ZBTB49 AL354822.1 TMEM81 PKP1 PLEKHG5 FAM86B2 PAK2 CBLN3 ZNF700 RIF1 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 mock v SARS-CoV-2 Calu-3 s2 4h polyA GSE148729 down DCTPP1 UBL5 TIMM8B FCGRT RPL12 CISD3 IRF3 LMAN2 TSPO TMUB1 YIF1A IFITM1 NDUFAF2 ANXA2 HLA-B TMEM54 ANXA13 FABP6 TUBA4A HLA-A SAP18 SFN TIMM10 PHB EXOSC5 AGTRAP ISG15 PKIG GADD45GIP1 TLCD1 EXOSC4 SAC3D1 OCIAD2 VKORC1 NMB TPRG1 UQCR10 CEBPD IFI27 KRT17 ADCY2 AQP5 S100A14 NDUFB2 CCNO MZT2A C12ORF75 COX6A1 KRT19 SLPI S100A2 COX7C KRT8 FTL BAX BANF1 SNRPB TYMP CYBA SYNGR2 TWF2 CAPG MRPL12 SPR EAF2 NDUFS7 LGALS1 ATP6V1F GALK1 RRAS MYDGF RPL26L1 NME1 CBR1 IFI27L2 DYNLL1 TPI1 PRELID1 CRIP2 RUNX3 MS4A2 DRAXIN BAD MMP1 MANF SERPINF1 CRB3 SPINT2 CYCS TF KRT14 GIPC1 RHOD MRO CTNNBIP1 KRT13 CD63 UPP1 RSAD2 IRF7 MXD3 IFIT1 GTSF1 CENPM CFD DNPH1 PRSS22 GRIA1 IGFBP6 RAMP1 IFI35 ANGPTL4 PSENEN PSME2 PFN1 AKR1A1 ATP6V0E1 CHCHD2 DMKN CST3 HLA-DQB1 SNRPD2 CTSH PPIB NDUFA13 GABARAP PSMB6 COX8A PRDX5 DRAP1 PSMB5 PFDN6 S100A6 TMEM160 RPL18 TMEM50B RPL35 RPS9 OAZ1 NDUFB7 FDX1 LYPLA2 RPL18A ICAM2 JTB EVA1B TRMT112 S100A16 PQBP1 ATP6V0B MPC2 SMIM22 COX6B1 IGFBP7 EFHD2 NDUFA4 NOP10 NUDT16L1 MARCKSL1 GUK1 CHCHD1 PIN4 NDUFB10 NDUFA7 GPX4 TMEM147 MIEN1 DAD1 TRIML2 CITED4 IER5L DPM3 UBE2S SNRPG PRR13 PDZK1IP1 TM4SF4 POLR2G ISCA2 MRPL46 LAMTOR2 SMCO4 MSRB2 RBM42 MIF DCXR PFDN2 PRDX4 PARK7 RABAC1 NFU1 TFPT DYNLT1 COPRS TTC1 MAGOH PLGRKT ORMDL2 MRPL2 C19ORF33 VPS72 LSM7 PIH1D1 PHLDA3 EMG1 NOSIP CKLF NDUFA8 POLR2J SSR4 ZNF593 PCMT1 ETHE1 PSMA7 CMC1 SSR2 MRPL17 AKR1B1 HSPE1 CUEDC2 EMC9 SF3B5 ETFB C1ORF122 TOMM5 TSEN34 SDF2L1 VGF LTC4S FBLL1 ZNF32 GOLT1A MEA1 MVD PCSK1N TNNT1 PTS FUOM BCL2L12 STRA6 BID CCDC153 SPATA24 SSNA1 ISOC2 L3MBTL4 RARRES2 TESC IFI6 PRSS1 POU6F2 ALKBH6 MRPS11 SCOC CDC42EP5 CYSRT1 MMEL1 HES4 CX3CL1 MDK SERF2 COPE CLIC1 TAF10 BLVRB UQCR11 PDXK ZFP82 PDLIM2 CENPV APOE CADPS CD68 SFTA2 ZPR1 ACOT8 TRAPPC1 ANAPC11 TXNL4A TRAPPC5 SCO2 TRADD ARL2 CLPP MRPS12 CPPED1 TXN2 HMOX2 FKBP2 AIP CD82 CRLS1 SPP1 FBXO27 PCDH11Y BOLA2B AURKAIP1 COA4 C19ORF53 BLOC1S1 C9ORF16 APRT COA3 RPL17-C18ORF32 FFAR2 RAC3 MZT2B ZNF524 CLTB ITPA NOXO1 TRAPPC6A NUDT14 METRN PRADC1 RPS19BP1 MPC1 F8A1 CYSTM1 JAK3 DNAAF1 PPP1R14B TIMM13 UROD SIVA1 FDPS IFT43 HLA-DRB3 EMC7 CST6 CD320 DNPEP SRA1 CDKN2A NT5C3B ZPLD1 OPRK1 DTYMK XKR9 ZCWPW2 POTEM GRIN2B PGP FIS1 EIF4EBP1 CISD2 POLR2F UGT1A1 MRPS15 DEFB1 SIRT2 MTHFS RANBP1 SULT2A1 GJB1 HAX1 AIFM2 MGMT KCNIP3 PSMA5 PIN1 TMEM138 MRPS34 ENDOG TUSC2 MT1G AS3MT MAPK8IP1 TIMM17A TMEM70 AK1 NAPRT JOSD2 DYNLRB1 RNASEH2C FBXO2 BCL7C CAPS C7ORF50 PXMP2 LAGE3 PAGR1 MRPL41 PMVK SLC22A18AS TMEM141 DNLZ NTHL1 CHCHD6 NDUFB8 SLC39A3 NOL12 PDF POP7 HSPBP1 NR2F6 MACROD1 ALKBH7 ECI1 NDUFS8 NME3 NTMT1 MRPL55 CARD19 CIB2 ZMAT5 CCDC167 CCDC61 EIF3CL YIF1B TP53I13 TMEM265 C17ORF49 LSM3 UQCC2 RPP25 ZNF428 COA6 ZNF576 PYURF MRPL14 MRPS18A TM4SF18 PHPT1 RDH5 NAXE FAM110D ENSA U2AF1L4 BORCS7 SCAMP3 ZNF511 EBF1 PDCD2L EMC8 SDHAF1 TACO1 COA5 TSR3 C4ORF48 NUDT22 FAM89B PAM16 MRPL22 FLYWCH2 MPG ZNHIT2 RPP25L GRM2 RPP21 INO80C SURF1 PPP1R35 MRPL58 PNMT DNAJC25-GNG10 HSD17B8 ST8SIA1 BNIPL TGFBR3L FDX2 SERF1A PSG2 ZNF716 ANKRD16 MIP AMER3 SGSM1 CTU1 CLUL1 HOMER3 ZNF843 BOLA2 ZNF492 MCRIP1 FAM156B PRRG2 DNTTIP1 ZNF709 PRSS33 LRRD1 POU5F1B CDHR4 MDP1 ZNF835 BEX5 MRPL36 KLHL34 ZYG11A RBAK-RBAKDN OVCA2 PLA2G2C GEMIN7 SLX1A MCRIP2 RFX4 C1ORF158 OXGR1 U2AF1L5 BSCL2 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 12h from GSE148729 mock v SARS-CoV-2 Calu-3 s2 12h polyA GSE148729 up NKX3-1 UIMC1 RSRC2 SEC16B BIRC3 IL6 GDF15 CCL2 VCAM1 EGR1 SQSTM1 NMI PTBP2 TNF DDX58 TBK1 IL1A CXCL10 IFITM3 CYP2J2 IFITM1 PLEKHF2 HLA-B NEDD9 LAP3 ZNF274 JAK2 IFNL3 BRD2 RBCK1 SNIP1 OAS1 PTX3 STAT1 TRIM25 IFITM2 PDE4D EIF2AK2 IL22RA1 OASL TRIM31 MOV10 FRMD4B CXCL2 ING3 IFNB1 ISG15 AKAP8L MAP3K1 NUB1 ARL14 CSF2 MX1 MYD88 WFDC5 OVOL1 ZC3H12C NR3C1 RBM39 FZD5 MT2A CXCL1 TNFSF10 TRPS1 IFI27 SIX1 HES1 DUSP16 EXT1 MT-ND1 PARD6B MTRNR2L8 ELF3 ZNF564 PNRC1 CFH MTRNR2L12 RICTOR MTRNR2L1 FAM83B MT-ND2 FAM214A MT-CO3 ZEB1 RND3 ANKRD33B SEMA3A ISG20 MT-CO2 ARID5B CMTR1 TNFAIP2 PTGER4 USF1 PARP10 TYMP BST2 SLC15A3 SMAD7 ITGAM APOL2 FBXO6 RHOB LMO2 IFI44 RBBP8 SLC1A3 EPSTI1 SPRY2 CDKN2B BATF2 NRIP1 RASGEF1B IKZF2 TOPORS ZNF830 CTAGE9 PTGS2 GATA3 ZNF184 TUFT1 BMP2 KLF10 ZFP36L2 GADD45B ZNF180 BDNF EDN1 PLAUR MITF TFAP2A ZNF217 SOX9 ATF3 TCF7L2 BCL3 FOSL2 CBX4 HELZ2 NUAK2 OGFR RSAD2 OAS3 IDO1 IRF7 CFB PGLYRP2 ZBP1 NLRC5 TAP1 CCL20 IFIT1 SECTM1 MASTL IFIT3 RTP4 HLA-F OAS2 PHF11 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 GBP4 DHX58 TREX1 USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 MLKL STAT2 PML PLEKHA4 NFKBIE ADAR NT5C3A PARP9 PARP12 SAMD9L HSH2D ADM NFIL3 PIM1 INHBA RNF213 IFI35 PARP14 SOCS1 SAMHD1 UBE2L6 TLR3 UBA7 SP110 ATP13A4 ACKR4 IRF2 AHR KLF4 ZFP36 IER2 IER3 FOS SNRK IRF1 RASGRP3 DUSP1 TXNIP DTX3L NFKBIA IRF9 JUNB PSMB9 GBP3 JUN IFI44L ARRDC3 RP9 PIM3 ERRFI1 CCNL1 THEMIS2 GTF2B YTHDC1 RBM11 RRAD NPFFR2 ZC3H12A DUSP8 SLC25A25 ZNF597 TRAF1 EGR2 NR4A3 IFNL1 RAB30 PPP1R15A CSF1 TRIM22 ZNF436 VCPKMT TNFAIP3 ZNF267 ZFP37 FILIP1L ZNF205 BBC3 AMOTL2 DUSP6 PPP1R15B NEURL3 FLRT3 TIPARP YOD1 CSRNP1 SERTAD1 ZSWIM6 CLCF1 BHLHE40 NFKBIZ TSC22D2 SERTAD2 ZNFX1 KANSL1 FOSB MSL2 PNPT1 DHRS2 C3ORF38 RLF MXD1 DNAJB4 INTS6 GPBP1 DUSP10 PDE4B TLDC2 EFNA1 PRR15 MRGBP ITPKC KLF3 HIVEP2 USP43 ZNF211 SFSWAP ODF3B REL MAP3K14 TAP2 SLFN5 CASP1 PPM1K IL15RA ZCCHC2 TRIM21 RNF31 USP25 ZC3HAV1 TRIM5 TDRD7 TRIM14 PCGF5 TRIM69 MAP3K8 RIPK2 IL15 AZI2 CXCR5 IRAK2 PRKD2 CXCL11 PELI2 GABRE IFI6 STX19 IL32 PER1 IFNL2 LAMP3 DDX60 SLC25A28 RNF19B LGALS9 XRN1 SP100 MX2 IFIT5 HERC5 TRANK1 GORAB DDX60L TMEM140 ADRB2 SAMD9 GBP1 CASP7 TP53BP2 MB21D2 PPP1R10 CD83 ETS2 PLK2 WEE1 ZNF649 CDK17 HDX RELB RCAN1 ETV7 BTN3A3 GMPR CPEB2 PMAIP1 TICAM1 CX3CL1 SLC28A3 ARL5B SP140L MTF2 APOL3 N4BP1 BTN3A1 MOB3C TRIM38 RABGAP1L PARP8 FMR1 OPTN GTPBP2 TRIM26 LTB DYRK1A BMF SESN2 CLK1 PLSCR1 NCOA7 HAND1 C4A BDKRB2 CARD16 PELI1 PI4K2B OTUD1 CYLD MTRNR2L6 C6ORF62 ZBTB10 RBBP6 REC8 CCNT2 SHOX2 ZMYM2 PPP2R2A MIER1 BCL6 DAPP1 SERTAD3 EPC1 RBM6 CCDC130 NFE2L2 PRKCE E2F3 KDM6A JMJD1C SHROOM3 TRA2A THUMPD2 CHD2 ARHGEF38 AMBRA1 CPT1B FBXW7 NOD1 RC3H1 ZNF627 ZNF613 ZNF224 ZNF821 ZNF197 TRIM34 ZBTB17 RPP38 TGIF1 TRAF4 UGCG SOX4 GATA6 LATS2 COL16A1 TMEM51 POGZ ZNF764 TBC1D22B SETDB1 PIP5K1A MED26 SPATA2 ZNF16 TIAM2 RNF111 MTMR3 INO80 ABTB2 ZNF140 PDZD2 DLC1 ZSWIM4 SKIL KBTBD2 ARHGEF28 CLK4 LCA5 CNP ZNF672 FRS2 CDR2 AGAP6 BRF2 KMT2E BAZ2B CCDC174 CWC25 PLPP3 FBXO38 RBM5 ZNF222 CPEB3 ARID4B PPP4R4 TLK2 ARL4A ZNF433 GTF2H4 ZSWIM3 RUFY4 ZNF92 DDX47 ZDHHC14 CLK2 ZNF606 AGAP9 AGAP5 ZNF823 MTMR10 RGPD6 ZNF625-ZNF20 ZNF416 FAM110B CTAGE4 ANKHD1-EIF4EBP3 ZNF689 MTRNR2L10 UBE2F-SCLY 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 12h from GSE148729 mock v SARS-CoV-2 Calu-3 s2 12h polyA GSE148729 down IFNAR1 PRKACA ACE2 PPT1 TMPRSS4 VIL1 ATXN3 MIPOL1 TERB1 NDRG1 ADAM9 AP2M1 LRRC19 PLS1 TUBA4A CYB5R3 ITM2A ALG11 STOM HS2ST1 KLK2 SCN3B LRRC2 EDEM1 AFMID PCSK7 TMED4 MTFR1 APOOL CLDN10 BPNT1 METTL7A FN3K ALDH6A1 GPR155 ACO1 RNF128 TSHZ2 PIGR POU5F2 ADCY2 ZC3H12D IGSF6 PPIL6 KLK11 CRYM RHOBTB3 TNS4 GALNT3 DSG2 WFDC2 BCAS1 SCIN SLC16A7 CYBRD1 NDRG2 DCDC1 TTC22 VTCN1 CD24 KCNK6 ATP1A1 TMBIM6 ACER3 GPR107 PRKCSH ACSS1 TM9SF3 LEPROT QSOX1 SPN SLC16A3 ORAI2 GANAB SLC11A1 SULT1A1 ALDH1L2 SLC16A1 KIAA0930 WFDC1 FUCA2 ALG14 TMEM45A PRR11 PPARGC1B OLFML2A SORT1 PDGFD MS4A2 DRAXIN TCN1 PBXIP1 IGFBP3 DZANK1 PLCXD1 PLCXD3 MAVS SLC24A4 PTCHD1 APLP2 TMOD3 SCNN1A FAM83F PROM2 DSG3 HACD2 FGF5 KITLG WNT2B CTRC TCF7 F2R SORL1 OR11A1 TMEM164 TRPM8 KCNJ16 MEFV KLRD1 CREG2 CD3G LILRB4 CRTAM GP2 CD96 NLRC3 DNASE1L3 TNNT2 RYR2 PLIN1 SYT12 CD84 CYP4F8 SNX22 CLDN2 ANGPTL4 LRAT TTYH3 TNS1 TNNC1 EIF2S3 PLIN2 ITM2C LYZ NUPR1 BNIP3 CD74 RBMS3 PSAP AQP1 KCNA7 C1ORF198 GNS EFHD2 USHBP1 FSCN1 OAT TMED2 BNIP3L CYP46A1 ADAM32 CYP1A2 STARD9 LIN28A ACKR2 TCF23 BEST1 OLFM4 MYT1L RHBG TTR TLCD2 SLC14A1 STC1 GPR157 TMEM120B TMEM213 CYP4F3 MAGT1 MOB1A PDZK1IP1 TM4SF4 CRYZ MRPL42 TIMP2 GNG12 HSD17B2 MGLL SLC39A10 FGF13 CHST6 TMEM245 ZBTB8A SERINC5 TNFRSF19 TMEM47 TRIM72 APOBEC3C HAMP XKR4 AKR1B10 ZDHHC15 CDH6 PCDH9 SMAD9 CHRNB4 RPAP2 ATP10B JSRP1 KRT26 ITGA11 SLC28A2 POU2AF1 TMEM212 CTSE MEDAG TFRC L3MBTL4 FGFR3 C2ORF83 CEACAM8 MMACHC SEC14L5 SLC35E3 GTF2H3 SEC62 TFPI2 MLEC GLG1 PCYOX1 DNAJC22 ZNF713 PROSER3 UGT1A6 SLC2A10 HOGA1 GALM ALDH2 SERPINB1 ITK ACTR2 RAB29 ZNF70 ZNF397 UGT2B15 MAST3 FLRT2 GNE KCNE3 PDK1 DAPK2 PAG1 NT5DC3 UPB1 PAPPA ZFP42 SV2B SLITRK5 TMEM130 KLK6 KLHL33 SLC6A14 LGSN GOLGA6C RARRES1 IL21R FCAR RNF125 PGK1 MASP1 SLC31A1 CA12 GNPNAT1 SEC22B FKBP14 FCF1 RYR3 SYAP1 ZNF471 PCDHA4 NNT WTIP ASTN2 ADH4 C12ORF45 MCFD2 PNPO ACBD7 SHISA9 PCDH11Y C5AR2 PARM1 XRCC2 TRMT2B ZNF587 OPA3 USP8 KCNJ6 PNMA2 ABCB6 SHH PRODH JAK3 SLC26A8 ATP6V0A2 PRKY AP1S3 GSDMA MCCC1 PPARA SPOCK2 LRPAP1 CPM SLC1A6 UGT1A10 GGT6 GAS7 SLC9A4 TEX15 NANOG ZPLD1 SLC44A4 PROM1 TXNRD1 CTCFL MROH7 ABCA9 GSR TTPA SLCO1A2 NOTCH3 TMEM192 LILRA2 IVD IDO2 SLCO1B3 ZNF780B PGBD4 ALDH1L1 CAMK2A PCYT1B KIF6 ABCA13 SERPINA4 GPLD1 HSD17B13 SLC29A4 CALU MCF2L2 ST8SIA4 RCSD1 PECAM1 CYSLTR1 UGDH AS3MT AHCYL2 BRCC3 NAALADL2 FITM2 HACD3 LRRN3 DSEL PLEKHB1 MPV17L FAM83A LANCL1 MAN1C1 NCR3LG1 SBF2 CCBE1 CLMP DISP2 MELTF LHPP GOLIM4 BCKDHA MFSD4B DTWD2 PCDHGB5 MGAM2 ARSD MACROD2 NIPAL3 CBX6 GPALPP1 SYT11 ARL10 CCDC69 ERLIN2 NCMAP PAIP2B GSTT2 SND1 RAB3B P2RX5-TAX1BP3 SGCB JAKMIP2 PIGN CXADR SLC4A8 SYNE3 PIGM SLC6A8 CNNM1 GABPB2 PDP2 CADM4 EXOSC6 SLC35A3 GNL3L FTO CRCP TFAP4 TCTN2 HIF3A GNG7 LYRM7 GABRB3 MR1 PEX26 BTBD19 ST18 GRM2 SNX27 VENTX LUZP2 LRRC74B FAM227A ZNF99 GATC PCDHGB7 ZNF492 PRSS33 ZNF835 SCML4 MGAT4C ZNF556 CCDC180 KIAA1328 ZBTB8B NXPE3 CNR2 ZNF891 OPRD1 FAM186A ZNF844 ZNF793 MORN1 BCO2 LY6K KCNB1 CA5A SLC35G5 VWA5B1 DENND2C MYLK3 FAM234B PCDHGA6 ZNF714 CCDC169 KLC3 SCRG1 DUSP19 ZNF347 CCDC122 ZNF814 FAM78B CES4A PTCHD4 DAW1 PLXDC1 SNTB2 DBT COL28A1 FUT11 ICA1L ABHD14A-ACY1 CNDP1 CDH7 PCDHGA5 NUGGC ZNF528 PPEF2 MOGAT3 DACT3 ADAM29 ARHGAP28 PAK3 TRABD2A RUNDC3A CYP27C1 NPIPA5 CRACR2A FBXO15 GABRG3 FRRS1L CCDC27 ADAMTSL3 GALR1 KCNG4 500 genes up-regulated by SARS-CoV-2 in human H1299 cells at 4h from GSE148729 untreated v SARS-CoV-2 H1299 4h polyA GSE148729 up MYH9 GNA11 F2RL1 EIF4H ADAMTS1 BIRC3 COL6A1 EGR1 CTSL SQSTM1 VDR BCAR1 PRKACA MAP7D1 ITGB1 TRIB3 AKAP8 NOL10 CCND3 TPM4 TPM3 TOR1AIP1 PVR FURIN RUNX1 PMEPA1 NCL KLF6 RYBP NFKB1 HMOX1 SERPINE1 POFUT1 PTX3 ST3GAL4 FOXA1 MUC3A RAB7A AAR2 CXCL2 AKR7A3 TGFB1 IL17RA CCDC86 FERMT2 ARL14 PLP2 SFXN5 SF1 ATF5 CXCL1 CEBPD GADD45A PTN MAP7 CCND1 TAB2 TAGLN2 RELT KHSRP GPAT4 TNFAIP2 NACC1 TAOK2 RMDN3 SIK2 IL4R ZNF316 VASP HBEGF GRINA FLNA SRPRA SNRPB GNB2 DNAJB2 ORAI2 ITGA5 HLA-E TMED9 ARHGDIA CMTM6 SLC6A6 RHBDD2 ABHD2 ZYX TIMP1 DHCR24 MYBL2 ARHGAP31 SDC4 SCPEP1 ELL2 CDC25A MAFG ORC1 SMTN GAPDH PPARGC1B DUSP7 BATF2 SNX8 ABCB1 ARL4C TPM2 AKAP5 G0S2 AKAP12 NUAK1 B4GALT5 CDKN1A MYC ZFP36L1 SLC2A3 DDX19A ZNF189 ACTB BDNF TRAPPC9 PLAUR HMGA1 JMJD6 CEP170B IFFO2 FAM83G WNT3 FGF5 WNT9A SOX9 MSX1 MAP2K3 MAP3K4 EFNB2 RGS3 SAFB FZD9 FOSL2 GLIS2 NUAK2 PHC2 DUSP2 GFI1 LHX2 IFIT1 GLIPR1 HAS3 NFKBIE TNFRSF12A FOSL1 ANGPTL4 NRIP3 NAP1L5 TTYH3 ETS1 KLF4 IER2 CNN2 YBX1 IER3 ACTG1 DUSP1 ICAM1 NFKBIA JUNB PXDC1 JUN SEMA3C DDX3X PLEKHG2 ADRM1 CALR BLMH ERRFI1 TUBB2A EHD1 PHLDA1 EFHD2 ZFP91 SUPT5H MARCKSL1 FSCN1 CCDC85B GEM RRAD MAGEA12 KIFC3 SLC25A25 TRAF1 NR4A3 B3GNT5 TNFAIP3 SOCS2 HDAC9 HIC1 LIMD1 STC1 MAPRE3 TOR4A AMOTL2 LIF DUSP5 CSRNP1 SERTAD1 MAFF SH2B3 SOWAHC M6PR PSMD13 PA2G4 PPP1R18 TOMM34 CORO1C C15ORF40 CAP1 MOB4 CMC1 GNL2 SGMS2 FXR2 VGF ADRA2C ENC1 SRXN1 PURB ITPKC RNF25 BLOC1S4 ATXN1L MED10 SLC35G2 NECAP1 MUL1 MAP3K14 MYLK2 FEN1 RASSF3 BNC1 HOXC10 SLC28A2 CREM IL27RA TPGS1 PTMS ACTN4 HS3ST3A1 ALYREF TFPI2 DNAJC7 GBX2 KIF3B FOXD1 CHD4 TOP1 LAMC2 MLF2 TP53BP2 RNF145 FOXC1 LIMA1 CD83 PLK2 AFF4 RELB RCAN1 TICAM1 CCDC47 PANX1 CHSY1 TRIM38 TRIM26 SERPINA1 ARPC4 BLVRB EIF1 MEX3A ITPRIPL1 GRAMD1B FJX1 CDC42EP2 IL1RAP BCAR3 FHL2 OSGIN1 SERPINB8 SLC25A32 AANAT NR4A1 ADAM19 ETV3 C1QTNF2 PCDHGC4 KCNH2 GNA12 RAB35 YKT6 TEN1 TXLNA CAMSAP1 OSTF1 PIK3CD SPEN IFNGR2 MMP14 NEDD4 SMPD2 STX18 AKIRIN1 SYAP1 SZRD1 FBLIM1 WTIP CMTM3 CDC37 AVPI1 CDC42SE1 HOXC8 PLEK2 EPHA2 DNTTIP2 LLPH CDCP1 SLC16A13 CLTB CHST3 FAM102A SYN1 CCDC71L LUZP1 DAPK3 KCTD10 AMOTL1 GNL1 RRP7A FLNC FHOD1 VPS37B SPHK1 ERCC1 NAB2 TNFRSF10A PRICKLE3 RIPK4 DTX2 NLRP3 UBE2Q1 WDR1 IL6R DGKG ECE1 TGFA OSTM1 STK38L LMTK2 EWSR1 ARHGEF37 TNKS1BP1 SHROOM3 ZNF774 SUN3 PPAN LRWD1 ZACN ZNF800 PTBP1 GSTM4 MAP3K2 NFYA LIMK1 RRBP1 TNC PPIF ERN1 PDAP1 PRPF4 RRS1 ACOX3 NFKBIB SUSD6 CSGALNACT2 HDHD3 BCL7C PEG10 KLHL18 ZNF335 GTPBP4 FEM1A TADA2B FAM168B C18ORF25 DLC1 HS6ST1 TRAPPC2L SYNGR1 TMX4 THSD1 ISG20L2 FHDC1 SHB KCTD11 TRIM47 MCTP1 ZNF697 RNF40 ADAT3 DNAJC9 DDIAS TDG DIDO1 KLHL42 PBDC1 GPATCH4 TNRC6A EIF3CL C16ORF72 CNST DENND5B ZNF609 BAZ2B DNMBP NOCT MAK16 UBE2O C17ORF49 BCKDHA RAPGEF6 IRGQ GJC1 ARAP2 DOHH FUBP3 DND1 PALM3 SF3B2 BTN2A1 FBXL15 BARX2 TSPAN9 KCTD13 NCDN ENTPD7 DNAL1 BCL7B LYAR NSUN2 GTF2F1 ASB6 TMEM158 TBX20 SART1 SH3GL1 SPATA2L LRP12 ADO GPRIN1 DIS3 ZNF658 SAMD4B TIGD5 NEFM POP1 F8A3 B3GAT3 PMF1-BGLAP CCDC43 PROB1 ISY1-RAB43 MALSU1 GOLGA6L4 SMIM11B KBTBD11-OT1 GOLGA8T C8ORF76 SHISA8 EEF1E1-BLOC1S5 MMP16 FAAP24 C2ORF49 ARMCX4 SURF6 ARL2-SNX15 TRIM44 HNRNPUL2-BSCL2 ZNF229 TBC1D3I NUDT18 C7ORF26 MAGEA2 NCS1 ADCK2 CBSL FAM131C ZNF552 CERS1 LRRIQ3 MIEF1 DNAJC5 SMN2 LRRC73 GCNT2 MAPKBP1 500 genes down-regulated by SARS-CoV-2 in human H1299 cells at 4h from GSE148729 untreated v SARS-CoV-2 H1299 4h polyA GSE148729 down SEC14L1 TRIM59 FGF23 PFAS KPNA2 ACADM MACF1 MIB1 SLC26A6 RBL2 GPT PFKL NBR1 ATXN3 CENPF WRN CIT SMAD3 UHRF2 ATM ING4 ARL6IP6 ACADVL ISYNA1 AASS HERPUD1 AKAP9 HSPA8 FAM72B SLC30A6 FCGBP STC2 TMBIM4 TMLHE ASF1A SLC25A40 PMS1 ZFAND1 N4BP2L2 CAV1 EIF4B PCLO MT-ND5 PTPN13 TEAD1 PNRC1 PAWR PLCB4 MT-ND2 MT-ND4L MT-CO3 CKS2 UTRN TJP1 EXPH5 MT-CYB ZNF33B MT-ND4 DCDC1 ARHGAP4 STMN1 PIEZO1 ATG16L2 TUBGCP6 GAA USP19 GIGYF1 CAD PPP6R2 TOP2A TICRR TROAP NLN C5 E2F2 LDLR HMMR FAM72D BUB1B KIF14 UACA ASPM SDHD ESPL1 ANLN CDCA3 HJURP DYNLL1 TTK KIF20A SCD LTBP4 PTCH1 AKT3 RMND5A MUTYH CHTF18 MAVS KLF11 ABCD4 CNOT6 PKD1 AXL BCAS3 MROH6 RHPN1 LAMA5 WNT5B HNRNPH1 SOX12 FZD7 NBEAL2 RNF44 EME2 MNT MIS18BP1 MXD3 STAG3 CKAP2L IQGAP3 PARPBP FANCD2 NCAPD2 KNTC1 ECT2 CKAP2 DEPDC1 CCNF FCHO1 HMGB2 KCNN4 PSAT1 TREX1 PLAC8 CCDC18 ACOXL SLC7A11 PIM1 RNF213 GDF1 CAV2 DPYSL2 PTGES3 CYTH3 R3HDM2 SMAD6 GDPD3 COX7A2L CPNE7 BTG1 GABARAP KLF9 PDCD4 DDX17 MXD4 TNS3 AGO1 STK38 ZNF692 FASN EIF4A2 IVNS1ABP EMC2 CCNL2 CTDSP2 CD164 AGO4 SLC38A2 AGPAT4 ZNF667 NATD1 ZNF292 PDE4A ZIC2 TIPARP ZNF367 TAF1D SLC29A1 SRP9 TMEM230 ACTL6A C2ORF74 HAUS7 C18ORF32 NEK7 RB1CC1 CDC25B DNAJB9 ARL6IP1 CKAP5 PAN2 OGT HAMP ANKRD1 ZDHHC23 LENG8 ID1 ANAPC7 INSIG1 C19ORF54 KDM3B CREBRF MCU ID2 KLHL24 CEP76 SLC6A9 GRAMD4 GSTCD LRRC14 ASNS ATF6B FAM161A WDR90 DERL3 PIKFYVE LY6G5B CYP1B1 CDKN2C CTSV GOLGA8B GOLGA8A GSDMB CFAP44 TMEM126B TMEFF2 MPHOSPH9 GMCL1 ARID4A LAMB2 CCDC77 VPS4B BET1 NPIPA1 XRN1 PILRB EFHC1 GTF2I CRIM1 IGF1R XRCC4 FMNL2 SLC25A36 WEE1 GPT2 PXK PARP3 GTPBP2 XPO1 CDKN1B CALM2 CEP152 BMF RAD52 ATF7IP GNE CBS DENND3 LPIN1 CLK1 KIAA1549L ROR1 COPS4 ORC2 AASDHPPT UBE2B DOK3 USP33 CDK6 WIPI2 STX7 RAB5B UBALD2 LRRK1 GEMIN8 CALCOCO1 CITED2 CGGBP1 CDK5RAP3 TBC1D17 TPCN1 MAN2C1 FAM114A2 CARD8 DCAF4 TSPAN5 ANKZF1 DYNC2H1 ZCCHC7 ERAP1 EIF2AK1 TXLNG TMEM123 CCNT2 HERC4 HLTF CDK10 PRSS53 FBXL8 LSS FASTK DNAH7 RXRB HBP1 DST ADCY4 LMBR1L SGSM2 FDPS SPG7 PUDP FDFT1 PDE3B PRKD1 SREBF2 STEAP2 ACACA MAGI1 CDK19 CYTH2 PIK3CB TXNRD1 ABCC10 SMC4 CCNG2 DPY19L3 FAM9C CHD2 TARDBP HSF4 SPG11 ZFYVE1 EPG5 VPS52 SLC38A9 TFPI UBR2 STK11 PRKDC PLD1 VPS50 USP49 HYPK CTBS ENOSF1 ABTB1 AAAS SLC22A15 RIDA MUS81 KAT7 HP1BP3 ANAPC1 SUDS3 ANKRD27 POC1A AKR7A2 GPX8 RMI2 DARS2 NEMP1 ADGRG6 SLC4A7 USP24 MLLT10 DNAJB6 ARHGEF28 HIVEP1 OSBPL7 CENPT PIF1 MYSM1 ZNF395 DPY19L4 UBN2 C11ORF54 JMY RHOT2 WDR62 PM20D2 TRIO PPIL2 SUGP2 HSPG2 VPS13A FRA10AC1 DOCK5 FANCE SGO2 LMLN LRRC37A GABBR1 NADK2 GPBP1L1 ZFC3H1 SIN3A CTC1 GUCA1B TM4SF18 PCMTD1 G2E3 SLC4A8 BROX WDR19 HYLS1 ARHGEF17 SLIT3 GARNL3 COG8 YBX2 RABGGTB ITPR2 BRD3 NKTR PABPC1L HINFP ELF2 FOXN3 METTL15 SPPL2B RNF38 MBTD1 TFAP4 DYNC1I2 PTGIS IPMK LZTFL1 DDX11 AKAP6 ODF2L S100PBP CEP41 MAMDC4 NEIL1 KLHL17 PCED1A MED12 AGAP4 KLHL12 BRD8 SMIM11A MSH5-SAPCD1 BLOC1S5-TXNDC5 U2AF1L5 ZNF844 NPIPA5 SPIRE2 ZNF117 PAFAH2 UTP14C D2HGDH PPAN-P2RY11 SETD6 NPIPA2 HOXB3 ATP8B3 ARL17A AP1G2 ZNF334 LRRC75A ATCAY TPTE AC244489.1 CDRT4 MIEF2 NRBP2 CRB1 NUDT13 TP53TG3F B3GNTL1 KCNQ5 TDRD12 BIVM-ERCC5 TBC1D25 AC133551.1 GPANK1 MEIOC FOXD4L5 HEATR1 ATXN3L GPAT2 SLC52A1 ACVR2B POTEF ZNF740 SPECC1L-ADORA2A INTS3 TMCO6 PRR5-ARHGAP8 ZNF781 ZNF300 ZNF839 KMT5C JMJD7-PLA2G4B TEPSIN WDR27 TMEM256-PLSCR3 RTEL1-TNFRSF6B PCDHGA3 NMT2 500 genes up-regulated by SARS-CoV-2 in human H1299 cells at 4h from GSE148729 mock v SARS-CoV-2 H1299 4h polyA GSE148729 up F2RL1 SUMO1 UIMC1 BIRC3 SUMO2 EGR1 PTEN SQSTM1 VDR RPL12 HNF4G SLU7 TPM4 PPT1 TPM3 PKM NDUFAF2 FURIN PMEPA1 NCL HMOX1 SERPINE1 FRMD6 COPB2 ATP1B1 FAU RAB7A OASL NPM1 MASP2 CXCL2 AKR7A3 EPHX2 FKBP1B CASP3 RAB5C PKIG C1D ATF5 NOMO3 RPS20 HOXC6 RPS17 RPS26 RPS12 LSM12 TPT1 SYTL2 RPL38 CNN3 RPL30 GADD45A PRDM1 PTN OTUD7B RPS18 RPL31 ZBTB20 RPL11 RPL7 TAGLN2 TTC14 TNFAIP2 GPR107 VASP GSN HBEGF FKBP8 ORAI2 SMAD7 ITGAM ABHD2 NET1 EXO1 MYBL2 ARHGAP31 SDC4 SCPEP1 MAPK6 ELL2 TMTC1 RAB13 PDGFC CLTA RPL26L1 PSMB7 TPM2 G0S2 AKAP12 NUAK1 B4GALT1 MYC BMP2 ZFP36L1 MMP1 SPINT2 SNPH HMGA1 CSNK1G1 SCNN1A GTF2IRD1 LRRC8E FAM83F WNT3 SFRP1 WNT9A DKK1 MSX1 FZD4 MAP2K3 GOLPH3 WWOX MLLT11 SAFB NXF2B TFE3 FOSL2 NUAK2 PHC2 RAB43 CENPN RINL IFIT1 GLIPR1 IFIT3 PHF11 CD274 CCNE2 STON1 NFKBIE SMC1B IFI35 ANGPTL4 SRSF4 KLF4 RPL8 IER2 YBX1 IER3 HNRNPM ACTG1 MAP1LC3B DUSP1 NFKBIA JUNB PXDC1 JUN SEMA3C RPL5 RPL26 NACA ACAT2 GABARAP NDUFS3 ARPC2 PAIP2 MATR3 CETN2 DDX3X NDFIP1 CNBP SOD1 TALDO1 ERRFI1 TUBB2A EHD1 RASSF5 DBI GPX4 GEM RRAD TRAF1 RBM24 FAM167A TRIM22 PCDHGB1 SOCS2 SAMD15 HERC3 STC1 AMOTL2 LIF DUSP5 SERTAD1 MAFF PJA2 PSMD13 UBE2N PA2G4 VMP1 PSMC1 DONSON POLR2J SSB SERINC1 CAP1 SNRPA CBX1 GNL2 TMSB10 AMIGO2 RPL34 PCSK5 TMEFF1 ZFAND2A GPR89A AFTPH WBP11 SGMS2 TLDC2 ZNF32 ENC1 SRXN1 IK NDRG4 MED10 MAP3K14 LAT2 JSRP1 POU3F2 ZCCHC2 CREM PCGF5 TMEM229B AJUBA PTMS DDX43 C3ORF33 LIN28B GAGE1 C22ORF39 ALYREF SMAD5 PET117 SEC62 CCDC106 GBX2 SAMD9 FOXD1 GJB2 GINM1 SRGAP2C POGK PJA1 LENG9 LIMA1 PLK2 RELB RCAN1 CCDC47 MDK FAM122C PANX1 TRIM38 IL7 CFLAR TRIM26 MYL6 SMARCE1 MEX3B SOBP PTPRE IL17D LMCD1 CDC42EP2 BCAR3 FHL2 OSGIN1 SPRYD4 SSTR2 NR4A1 ITGB6 SLC6A17 GFI1B PSMD9 RAB35 PSMG2 YEATS4 IDI1 STX11 PELI1 NEDD4 UXS1 HMOX2 PARS2 UCK1 SNRNP27 FUNDC2 SZRD1 RDH16 SYN3 CHMP1B ASAH1 BTBD1 CMTM3 CDC37 C11ORF98 AVPI1 CDC42SE1 CTNNBL1 HOXC8 THAP7 XRCC2 KTN1 NSRP1 DDX50 ZNF518B IFT81 JRK CLTB ELK3 RAF1 RRP7A VPS37B NAB2 HEXIM1 RIPK4 DTX2 ZFHX3 SNAP29 WDR1 IL6R ROCK2 ADD1 DGKG SLC9A4 ABCA9 AP3B2 SCHIP1 COQ10B FBXW7 ZSCAN12 ZNF641 PRMT9 SLC46A1 GSTM3 PTBP1 SCAF11 GSTM4 PEA15 GAGE12G RANBP6 PDAP1 LIN9 PSMA5 THOC3 FAM207A CDK7 LATS2 SNRPC GTF2H1 NFKBIB TXNDC9 PDHA1 HDHD3 DBNDD2 METAP2 SEL1L3 ASAH2B BICD1 TADA2B PXMP2 HS6ST1 TRAPPC2L ANXA6 MRPS21 DDX28 NDUFB8 TMEM135 TLK1 MCTP1 ZNF25 RFC3 DDIAS TDG CDK13 TMTC3 KLHL42 FAM217B MRPL21 DENND5B BAZ2B NMD3 C17ORF49 NDUFC2-KCTD14 JOSD1 POLR2J2 ZC3H13 FRG1 C1GALT1C1 TBPL1 TMEM38B DND1 SLC25A17 FGGY SF3B2 LUC7L2 TCTE3 EML1 RBM19 CXADR KIF1B BARX2 TSPAN9 ZHX1 ENTPD7 BCL7B MYOM3 EXOG GTF2F1 ASB6 SLC36A4 PNPLA8 CAAP1 DENND1B SPATA2L LRP12 ADO GPRC5B LRRFIP2 PHTF1 SBDS TUBD1 DTNBP1 GALNT13 TMF1 C12ORF73 POP1 LYRM4 F8A3 INO80C ISY1 MALSU1 RBM15B MAP1LC3B2 GOLGA6L4 SMIM11B KBTBD11-OT1 CHN1 NBPF12 CTAGE4 KIAA1328 ZNF347 GOLGA8T C8ORF76 SHISA8 C2ORF49 SURF6 ZNF229 TBC1D3I CBSL MIEF1 GCNT2 POTEE LHFPL4 ZNF346 ANKRD23 DZIP1 GAGE12F ZNF493 P2RY11 SMIM4 SOGA3 ARL14EP NUBPL CDK3 BEND4 FBXO22 C20ORF144 KCNK3 ABHD18 PUS3 DNAJC14 MEF2B PTGES3L-AARSD1 CKLF-CMTM1 XAGE1A CTTNBP2NL LSM11 SPDYE16 NNAT ATP6V1C2 ZNF852 GAGE13 GOLGA6L22 PCDHGA10 KBTBD11 TP53TG3E MTM1 AKR1B15 SCG2 RFFL TP53TG3 UTP23 IFT52 FAM200B EEF1AKMT1 WDR87 ZNF570 PCDHGB4 500 genes down-regulated by SARS-CoV-2 in human H1299 cells at 4h from GSE148729 mock v SARS-CoV-2 H1299 4h polyA GSE148729 down NUP210 DCTPP1 EMC1 DDX10 MDN1 LARP1 PFAS DGAT1 MACF1 SLC26A6 GPT DYNC1H1 ZNF274 FAR2 UBAP2 WRN CIT TLE3 PIGO UHRF2 ACAA1 PABPC4 ACADVL AASS NUP214 USP54 PABPC1 PLAT AKAP9 USP21 HSPA8 ASAH2 FAM72B FCGBP ATXN2 FBXL6 WDR24 NDUFV1 IFT122 PCLO MT-ND3 MT-ND1 MT-ND5 MTRNR2L8 MT-CO1 MT-ND6 PKP4 MTRNR2L12 MTRNR2L1 MT-ND2 MT-ND4L MT-CO3 SLX4IP UTRN MT-CYB MT-ATP6 S100A2 MBNL2 PLA2G7 MT-ND4 MT-CO2 TMEM94 POLG SLC12A9 ARHGAP4 ADCY7 PIEZO1 MBD6 ATG16L2 MICAL1 DPP7 AKAP1 TUBGCP6 GAA SEC24C USP19 CD37 GIGYF1 CAD SPATA20 ADGRE5 TYK2 NLRP1 TICRR TROAP CDKN3 E2F2 LDLR KIF18B ARHGAP29 ASPM TDRD9 ESPL1 FAM72C CDCA3 CDC20 SH3PXD2B LTBP4 ADIRF DZANK1 ZNF195 MUTYH CHTF18 KLF11 ABCD4 PKD1 PLPP2 TONSL BCAS3 MROH6 JAG2 ALS2CL MROH1 SLC26A1 MYH14 MYO19 SLC52A2 RHPN1 LRP5 WNT5B HNRNPH1 SOX12 FZD7 NOTCH2 NBEAL2 KMT2B RNF44 EME2 MNT SBNO2 ATG2A RAD54L STAG3 IQGAP3 FANCD2 NCAPD2 KNTC1 CENPI LRR1 LAG3 TREX1 CNR1 NAV3 STAT2 TCIRG1 RNF213 SHISA5 PLTP R3HDM2 GDPD3 CPNE7 BTG1 KLF9 HCFC1R1 CHORDC1 CCNL1 TMEM259 AGO1 STK38 ZNF692 FASN EIF4A2 IVNS1ABP CCNL2 CDK11A RGS5 SLC38A2 ZDHHC18 ZNF880 MAP4K1 DGKQ SYNGAP1 TIPARP ZNF367 TAF1D MSL2 VAMP3 CUTA SLC29A1 PUS7 HSPA1A FAM122B PRPF8 FAM117A CDC25B USP10 DNAJB9 PAN2 OGT LENG8 COL7A1 C19ORF54 DPH2 ELMOD1 CEP76 FAM189A1 FAM110A LRRC14 ATF6B WDR90 PIKFYVE LY6G5B ANKRD13B CYP1B1 ATP1A3 GOLGA8B BRICD5 OTUD6B GOLGA8A FAM13B LAMB2 SMG1 PILRB ENTPD4 SDAD1 SRRM2 WEE1 PRRC1 PXK GTPBP2 CTSA AMPD2 RAD52 CBS DENND3 SESN2 LPIN1 CLK1 PNMA3 CYP2C8 KIAA1549L P2RY8 PUM1 HSPA1B FSD1 TNFRSF25 VPS36 PIAS3 NADK DOK3 DICER1 CDK6 ATG9A DDX56 ALG3 DHX35 ROBO3 MTRNR2L6 NXNL2 GEMIN8 CALCOCO1 C6ORF62 CHKB CDK5RAP3 LTB4R SLC25A10 FAM193B SUV39H1 MAN2C1 INPP5E THBS3 GPCPD1 WDR75 NDOR1 DMPK CDK10 SPNS1 ACTR1B MAP3K3 PCDHA12 ULK3 PRSS53 ABCB6 AMH FBXL8 LSS TAF1C ATP13A1 FASTK ZFYVE26 SKIV2L NFATC4 HBP1 DST NISCH SGSM3 PCID2 SGSM2 SPG7 CCDC130 GHR ZNF674 CLCN2 PLXNA1 STEAP2 ACACA CYTH2 ABCC10 AMOT MEN1 SETD5 PTP4A3 CBX7 TNPO2 ABCA3 HSF4 CPT1B PEG3 VPS52 FSD2 IQCJ-SCHIP1 SLC38A9 ADAMTSL4 SLC26A11 PRKDC TECPR1 USP49 CTBS HUWE1 SLC5A6 KLB LCAT SLC23A2 MUS81 PIDD1 POLD3 RECQL4 GCN1 MLLT1 MTRNR2L4 ARHGEF1 CYSLTR1 ANTXR2 NAPRT NEMP1 F11R ADGRG6 SLC4A7 CELSR3 ATXN2L NEURL4 GGA3 NOL6 OSBPL7 CENPT ARHGEF19 TLL2 MYSM1 UBN2 TMEM131 HCFC1 DISP2 ZBTB45 HAUS5 CPSF1 RHOT2 WDR62 RAD9A SLC27A3 SZT2 SPATA13 AGAP6 ZNF341 NLE1 VARS2 STK36 ZMIZ2 C11ORF68 HSPG2 NCKAP5L MORC2 DOCK5 SGO2 LMLN LRRC37A GABBR1 ODF2 PRRC2A SIN3A IRF2BP2 TRIM66 BDH2 WDR19 HYLS1 ARHGEF17 P3H1 ADARB1 ATAD3B YBX2 ITPR2 NKTR MFSD10 PABPC1L ZDHHC14 CD3EAP RASSF7 FOXN3 SRGAP2B SPPL2B DDX51 STK11IP MBTD1 RIN1 IPMK ZNF418 ATN1 LLGL1 NUDT22 GRIN2D DDX11 CNTROB EML3 ENGASE CNTNAP1 TMEM175 QTRT1 OGFOD2 GNB1L ZNF276 MAMDC4 KLHL17 PCED1A SH3D21 IGF2BP1 NBPF6 RTEL1 MED12 GPR89B ISY1-RAB43 WDR83 METTL17 KLHL12 SMIM11A MSANTD3-TMEFF1 NPIPA7 TEN1-CDK3 CTAGE8 MSH5-SAPCD1 CBWD3 ARHGAP33 OSBPL3 RNASEK-C17ORF49 PLEKHG5 ABHD14A-ACY1 NPIPA5 D2HGDH PPAN-P2RY11 SETD6 NPIPA2 HOXB3 ATP8B3 AP1G2 NRBP2 KCNQ5 TDRD12 BIVM-ERCC5 TBC1D25 HEATR1 ATXN3L GPAT2 INTS3 TMCO6 JMJD7-PLA2G4B TEPSIN WDR27 TMEM256-PLSCR3 RTEL1-TNFRSF6B PCDHGA3 MPPE1 YJEFN3 CDH24 AC136616.1 CCDC102B INPP4A NXF2 NKIRAS1 POMT2 EGFL8 DCLK2 PAPOLG FAM156A KIF7 SFI1 CCDC74B DTX3 L3MBTL2 MYH15 CGB8 ERCC6 SMARCAL1 CCDC169-SOHLH2 RBM14-RBM4 GOLGA8R AKTIP TMEM240 THADA TP53TG3C PLEKHG4 MYH3 APH1B 500 genes up-regulated by SARS-CoV-2 in human H1299 cells at 36h from GSE148729 mock v SARS-CoV-2 H1299 36h polyA GSE148729 up DCTPP1 UHRF1 HSP90AB1 POU5F1 HYOU1 VDR VCP PFAS PCK2 DDX21 EZR CYB5B AATF TMBIM1 ECSIT NCL CEP68 ACAA1 FBL PHB2 PSMD4 PTX3 TUBA1C STAT1 HLA-A ABCG2 NT5C PHB NPM1 AAR2 PES1 AGTRAP AAMP CCDC86 THOP1 UAP1 ZCCHC3 FARS2 CLDN10 TFAM YARS2 FKBPL ZNF410 ATF5 MKRN2 ENO1 PLEKHO1 RPS26 METTL23 GPX2 KIAA1143 RPS29 KHSRP ARF3 NACC1 TOMM40 SLC3A2 PGD RPS6KA1 SNRPB QSOX1 ITGB5 EIF3B URM1 HLA-E SLC6A6 SNRNP70 SLC1A5 MYBL2 TK1 CDKN3 SCPEP1 SPR MGME1 CDCA5 SPAG5 KIF2C CDC25A FUCA2 DLGAP5 RRM2 SHMT1 BIRC5 KIF4A GSTO1 CDCA2 TPX2 TBL2 CDC20 ALDH9A1 CENPW TPI1 CD163L1 AIMP2 B4GALT1 ABCF3 CKS1B CYCS SLC52A2 TPD52L1 TFIP11 LAMP1 UMPS FAM50A CENPN ARHGAP11A CENPA GINS2 TACC3 GPR176 RACGAP1 MAD2L1 CENPP HMGB2 CENPH NDC80 CDT1 XRCC3 NEFH PLAC8 NT5C3A HAND2 ETS1 EPAS1 TUBA1B CHMP4B PEBP1 MRFAP1 TJP2 FABP5 BCAP31 EEF1B2 GABARAP COX8A PRDX5 NME2 C1QBP TUBB GLUL CNBP ADRM1 DHX30 RAPGEF3 PSMA6 RBM3 ANXA1 GM2A SLC25A3 EFHD2 CFDP1 RPS3 NDUFA4 RAB9A PGRMC1 MIEN1 ZDHHC18 CCDC85B TAF11 KIFC3 TGFB1I1 TMEM14B TNFAIP3 HMGN5 FUS HERC3 PCBD2 TBC1D30 ZNF263 NDUFS2 PDLIM1 TXNDC17 RBM42 MRPS33 ILF2 PSMD13 SMIM20 PA2G4 MAGOH ORMDL2 C19ORF33 EBNA1BP2 ZMAT2 SAR1A PIH1D1 POLE3 EMG1 NDUFA12 DKC1 PTDSS1 SSB SLC10A3 HMGN4 UXT TUBB6 NUP93 PITPNB TUFM NAA20 TAX1BP3 LDHB GPR89A ODC1 RUVBL2 FXR2 SKA2 RANGAP1 ARGLU1 KRCC1 GNAZ NOP14 HNRNPA0 ARFIP2 PGM1 CSRP1 CHSY3 SERPINB7 CTDP1 MAP3K14 FEN1 NAGPA BATF3 GCAT AJUBA TFRC CDKN2C MCM7 PRTFDC1 MAD1L1 ASRGL1 EIF3A C3ORF80 TNFSF13B PPIL1 TMEM140 C4ORF36 ZNF468 TWISTNB ANP32B NCEH1 TRIM26 MTX1 KLHDC8B NBPF10 CALD1 ADORA2A SLC6A17 FBXL5 PSMD7 PSMD9 PSMD11 SAMM50 ACTR1A PEX2 RANGRF SSU72 PPIE NFATC2 ADPGK APMAP FARSB BAK1 POLD4 HTATIP2 PSMC5 PHGDH COX20 CRLS1 STX18 TOMM22 PSMC3 ZNF330 UVRAG CREB3 CNPPD1 COA4 BST1 APRT C11ORF98 CNPY2 CIAO1 GGCT PLEKHJ1 CTNNBL1 GTPBP6 FIP1L1 DDX54 DCAF4 TRMU ZBTB10 LTV1 RPF1 HNRNPD SMS DUS3L PCDHA12 PCDHAC1 VPS18 FLII TSTA3 TTLL12 DDX39A TELO2 NOP56 BRD9 ILVBL SLC39A7 GNL1 TSSC4 AFG3L2 PSMD2 XRCC6 NRF1 RPS6KA4 AAGAB TMCO4 GMFB CEP72 LRPAP1 DNPEP CLPTM1L GTF3A DPEP3 TTPA MYO1C ATG101 PRR5 PEG3 MRPS22 MRPS7 STK11 ZNF800 ITGAE GAB3 MTHFD1L BTN2A2 SAP30BP CIAPIN1 RNF4 F12 SULT1A3 MCF2L2 GUSB PEA15 RCN1 GAGE12G AIFM2 PPIF CDK11B PPM1G PRMT3 GTF2H2 RPP14 POLDIP2 MRPL4 DHX37 MCMBP HNRNPAB SHMT2 HRK ACOX3 TXNRD3 HSPA9 TXNDC9 OXR1 ECHS1 NANS VANGL1 GINS4 NOL6 SRPRB MRPL41 HES6 RERG POLR3K ARHGEF19 MRPS21 MSANTD3 GFRA1 PHRF1 WRAP53 CLEC11A RABL6 ZNF787 ELF1 ADNP2 HNRNPDL TRMT10C GPATCH4 RPL39L TIMM17B SMYD5 EEF1E1 SMYD2 NOP16 UQCC2 FANCE TMEM117 COA6 ECHDC1 SYDE1 CD99L2 KIF1C EIF5 DNAJC1 LRP4 TSPAN9 TSPAN17 MED8 ACOT11 PODXL2 FTSJ3 DDX47 CHST14 MRM2 LCMT2 UTP14A NAT10 TIMM22 DOK1 SMG5 CADM1 TOP3A ABT1 SART1 PUF60 KRI1 WDR46 FAM89B PAF1 GCFC2 GPRIN1 CCDC103 PINX1 TMEM242 EIF2S2 ZNF773 SLC18B1 CBWD5 ZNF582 SLC43A1 COMMD3-BMI1 ARPC4-TTLL3 HOXD8 CCDC43 ISY1-RAB43 PSTK PPP1R35 PARL RRP8 TIMM8A CHKB-CPT1B NME1-NME2 SPDYE2 DCAF8 HSPE1-MOB4 CHN1 BLOC1S5-TXNDC5 RNASEK-C17ORF49 ANKHD1-EIF4EBP3 MIEF1 AC244489.1 GPAT2 RTEL1-TNFRSF6B GAGE12F TP53TG3C GAGE12E C11ORF45 RHOJ NPIPA8 AC012314.5 TTLL11 PHF14 AC012314.3 NGRN MAGEA1 XAGE1B RHOXF2 HDDC3 P3H2 MOCS1 CCDC159 GAGE2A LARP1B RNF103-CHMP3 CKMT1A AC012314.4 CLVS2 CHST12 TVP23C RCC1L BORCS6 TBC1D1 CCDC181 MAGEA2B CALHM2 AARSD1 XK C12ORF43 AC012314.6 ZNF695 500 genes down-regulated by SARS-CoV-2 in human H1299 cells at 36h from GSE148729 mock v SARS-CoV-2 H1299 36h polyA GSE148729 down F2RL1 RB1 MDN1 MACF1 RBL2 MIPOL1 KLF6 CLCN6 HOOK3 SMAD3 UGGT2 TTN CLDN15 UHRF2 DNASE1 SULT1B1 HBQ1 ATM CLIP4 BRCA1 EPS8L2 SLC30A7 RBM41 FKBP15 AKAP9 MOV10 SMARCA4 NPIPB3 SFXN5 SLC25A39 PCMTD2 PCSK7 USP34 LYPLA1 VPS13B ZKSCAN1 MCL1 NPHP3 RASEF PCLO NR4A2 NFAT5 PPL PNRC1 TCP11L2 PRKAA2 MT-ND4L SATB1 ANKRD36C ZNF467 ZBTB20 RPS27 TTC14 MAPK8IP3 MICAL1 TUBGCP6 GGA1 LRP1 ZYX ITGA7 ICAM5 SCD LTBP4 ARL4C UPK3B CHIC1 TMEM182 PTPRS MYBL1 CDKN1A ZFP36L1 RUNX2 DDX19A OBSCN PIK3IP1 B4GALT6 PKD1 MROH6 SLC2A4RG LAMA5 WLS FGF5 SOX9 BMP1 SORL1 TNFRSF1A EME2 MNT RGL2 SBNO2 RAB43 MAPK13 PDLIM5 CD226 PASK KNTC1 KCNN4 CFD SFT2D1 STAT2 PSAPL1 RNF213 PARP14 PLAU RIMKLB ZFP36 IER2 IER3 TMCC3 IRF9 SEMA3C CPNE7 TAPBP ARRDC3 CHORDC1 CAMTA2 ERRFI1 CCNL1 MKNK2 CCDC57 PHLDA1 TRAPPC2 EIF4A2 CCNL2 ATP2B1 SLC38A2 STARD9 SRPX VAMP1 EFCAB3 STC1 LIF SH2B3 MAGT1 VMP1 ALKBH3 UGT8 MOB4 RPS6KA3 ELOVL7 MRPS30 SEC24B HSPA1A PCSK5 MORC4 MXD1 VGF PAN2 OGT LENG8 ID1 PURB SPATC1L KRBA2 MYH7B PPP3CB ELMOD1 RWDD4 TMEM169 ABL2 STXBP1 IFT88 GRAMD4 LRRC14 JSRP1 SPPL2A MORC3 FAM71E1 LY6G5B ST8SIA5 LRGUK RCE1 GOLGA8B GABRE GOLGA8A C8ORF88 ALG10B PNKP LAMB2 SMG1 ZNF623 NHS AHNAK2 NBPF11 SHPRH TTC31 KIFC2 STARD4 NPIPA1 PILRB EFHC1 PCYOX1 ATRX ENTPD4 LPCAT1 CEP290 PNISR FMNL2 DGKH RHBDF2 IRS1 ZBTB33 ENO2 AKAP11 MAST3 PDE7A ZNF221 RAD52 ZNF177 BANP HCN3 RALGDS LPIN1 ZNF469 DNM1 KIAA1549L UNC80 TUBB3 CSMD2 SPRY4 B4GALNT1 RNF125 HSPA1B TNFRSF25 RANBP2 AGO2 TNKS CDK6 OTUB2 UBA6 ZNF44 CHKB RPL17-C18ORF32 MAN2C1 CARD8 PHC3 ANKZF1 ALDOC SOCS6 ZSCAN30 ZNF518B GOLGA4 CDCP1 DMPK CDK10 TEP1 PRSS53 HAPLN3 HOXB6 PLK3 SYNE2 FBXO10 MZF1 TAOK3 CACNA1A TMEM154 VPS13D SRCAP SSH1 DST NISCH SGSM2 FAM219B SPG7 TRAF3IP2 HMGA2 KAT2B ITGA3 TMEM79 RIPK4 SFT2D2 SLC5A3 CRYGS CPM NPAS2 TRPM7 LCORL FAM3C LIG4 NCOA2 PLXNA1 WWTR1 PLXNA3 LPP KMT2C VWA1 DNAH8 TTC6 ARHGAP32 HECTD4 NF1 POTEI SYNJ2 KCNAB1 CPT1B SPDYE6 RHD ZNF780B ZNF133 ZNF169 ZMYM6 ZCCHC4 CTBS HACD4 ABCA5 TRIP11 SUCO PHF6 CSAG2 GAGE2E GPAT3 DMTF1 MAPK12 HOXB4 BIRC6 RECQL4 TNFRSF6B MMP17 DCBLD2 SLC4A7 PCNX2 THAP1 LYST CNOT4 TIAM2 TNKS2 SKIL SLC25A37 CTXN1 GAMT MPV17L MANBA SLC44A5 REV3L LCA5 PTAR1 ZNF718 CCDC14 SLC9A7 APBB2 CHST11 CAPRIN2 ADAT3 PHF20L1 SLF2 PAXBP1 RC3H2 SNX18 SACS OPHN1 MAP4K5 EIF3CL PDE8A FOXN2 RBM5 VPS13A RPAP1 ZBTB7A TBC1D32 LRP5L DOCK5 RAPGEF6 NEDD8-MDP1 SYT11 KMT2D LMLN NDST2 UBAP1L POLR2J2 ZNF112 GABBR1 ETNK1 DGKD ZFC3H1 ZNF121 TYW5 INO80D CARD9 ICOSLG P2RX5-TAX1BP3 PCMTD1 ALG6 VPS13C ADARB1 MLH3 ANKIB1 NHSL1 NKTR PABPC1L SLC17A5 ZDHHC8 BRWD3 SRGAP2B NR6A1 CEP295 HELB SLC36A4 IPMK KLHL3 RNF207 SLC2A13 HECTD2 SYCP2 PREPL TAOK1 FAM135A DCAF10 NPAT TTC37 PRAF2 DLGAP4 ZNF638 NBEAL1 MAMDC4 LIME1 PCDHA5 CLIP3 PCDHAC2 ATAD3C RTEL1 GPR89B GREB1L AGO3 RNF169 POC1B-GALNT4 GOLGA6L4 C2ORF68 TMEM189-UBE2V1 CBWD3 MSH5 MAGED4B NBPF12 PRICKLE4 AL354822.1 PLEKHG5 RIF1 ZNF793 PCDHGA6 SNTB2 ABHD14A-ACY1 MMP16 ARL2-SNX15 MAPKBP1 PPAN-P2RY11 HOXB3 ARL17A ZNF334 NRBP2 TP53TG3F ATXN3L POTEF SPECC1L-ADORA2A INTS3 PRR5-ARHGAP8 ZNF300 JMJD7-PLA2G4B WDR27 CTTNBP2NL SPDYE16 RFFL WDR87 EGFL8 PLEKHG4 ZNF141 KIF27 PCDH18 ZNF490 TTLL3 RNF170 AK7 RSPH9 DCHS2 ZNF329 ZGLP1 PRRT1 FSD1L DENND6B GNPTAB PCDHB11 ZNF527 FOXL2NB CSAD TMEM249 DLK2 B3GALT1 B3GNT4 CCDC144A STXBP4 ZNF670-ZNF695 ZNF525 POLR2J3 SULT1A4 SRRM5 DNAJC6 FBXL4 GTF2H2C LRRC37A2 ZNF585B C12ORF56 PBX4 500 genes up-regulated by SARS-CoV-2 in human Caco2 cells at 4h from GSE148729 untreated v SARS-CoV-2 Caco2 4h polyA GSE148729 up F2RL1 BCL2L1 BIRC3 EPS8L3 GDF15 EGR1 MALL FGF23 PTPN3 BCAR1 ITGB1 YWHAZ DDX21 ASAP2 RNF24 BAIAP2L1 EPB41L1 YWHAG TRIM15 EZR RASA3 ACSL5 RUNX1 PMEPA1 KLF6 TLE3 SMAD3 SERPINE1 FRMD6 TUBA1C REG4 SFN STOM TGFB1 EGFR HSPA8 ARF6 FERMT2 HKDC1 RAB10 PLEC SPTBN1 LRRC8A RILP CD55 CHMP2B MCL1 CAV1 RNF128 MYO10 CEACAM6 KRT18 ITGA2 KLF5 RGS2 TM4SF1 THRB PARD6B GCNT3 YAP1 SH3RF1 S100A14 LRIG3 LMO7 C6ORF132 TNS4 SERPINB2 SLC2A1 GADD45A KRT19 RND3 FMN1 FOXQ1 GPRC5A CEACAM5 KRT8 CEP170 DHRS9 CCND1 RELT TMC6 AQP3 IL4R ZNF316 SH3TC1 VASP FLNA LRP10 MYADM LMNA SLC16A3 ORAI2 EHBP1L1 INF2 LTBR RHOB ZYX SDC4 AREG MYO1E LDLR ARHGAP29 FKBP5 UACA SPRY2 PPARG SLCO4A1 GRB10 DUSP7 SPATS2L ARHGAP23 ARNTL2 MTHFD2 CXCL8 ARL4C FGFRL1 PTGS2 AKAP12 PLCXD1 KLF16 B4GALT5 CDKN1A MYC ZFP36L1 STK4 KLF10 MMP1 KLF13 GADD45B AXL FGFR1 EDN1 PLAUR MITF HMGA1 LAD1 CLDN4 ITGB4 SH2D3A CEP170B SLC9A2 PLCD3 SEMA4B PPP1R13L FAM83F FAM83G SLC38A1 SLC7A5 EPPK1 ITPR3 ARHGEF16 EPS8L1 SLC7A1 SOX9 AXIN1 DKK1 MMP3 TCF7 JAG1 F2R IPO7 EFNB2 TNFRSF11B CBFB TBC1D8 UPP1 MAFK RNF44 TRIM8 TNFRSF1A PHC2 LFNG PLEKHG3 OGFR MIDN DUSP2 CCL20 PRSS22 NAV3 MLKL HAS3 CLDN2 TINAGL1 SOCS3 TNFRSF12A PSAPL1 SLC7A11 FOSL1 F3 EGR4 EFNA2 EPHA1 CD59 AHR CAV2 EHD4 ETS1 ZFP36 IER2 LRFN4 IER3 FOS IGFBP4 ACTG1 YBX3 MAP1LC3B SGK1 CDC42EP1 JUNB SMAGP TJP2 PDGFRA MAT2A PRRG3 LITAF DRAP1 RAP1B SH3BGRL3 VIM ITPRIPL2 ESAM PLEKHG2 PIM3 S100A16 ERRFI1 TUBB2A EHD1 FNDC3B PHLDA1 ELOVL1 FASN CYP2S1 PMP22 CD9 KDM6B MFHAS1 KIFC3 SLC25A25 PPP1R15A LHX6 TNFAIP3 SOCS2 KRTAP3-1 SKI DUSP6 LIF DUSP5 CSRNP1 SERTAD1 CLCF1 MAFF PFKFB3 IL11 SH2B3 SOWAHC S100A11 SEH1L PPP1R18 TOMM34 TIMP2 TMEM185B GNAI1 GJA1 TNFRSF21 FAM107B BZW1 KCTD9 TUBB6 PITPNB GNL2 TMSB10 GEMIN5 ARHGEF18 RHPN2 VGF ANKRD1 ID1 SRSF7 ENC1 SRXN1 SNX9 MRGBP CLIP2 KDSR C3ORF52 MAP3K14 ABL2 URB2 PAQR5 SMOX IL27RA INPP1 ANKRD13B HNRNPF TRNP1 MTCL1 C6ORF141 CRABP2 SLC20A1 RNF19B BCL10 ST3GAL1 TOP1 WSB2 LAMC2 EMP1 RNF145 HES4 ETS2 CEACAM1 PLK2 BAZ1A DUSP4 NOSTRIN ARL5B NCEH1 IRS1 CFLAR EIF1 RALGDS TRIB1 PHLDA2 FHL2 SLC25A32 TNFRSF10D TUBB3 SLC17A9 KRT6A CARD11 NR1D1 ADAMTS9 SPRY4 NUMBL IFNGR1 ITGA6 PRKCD AGO2 DOT1L MAP4K4 TBX2 SPEN NFKB2 TNFAIP8 STK10 SMURF1 TMEM43 FBLIM1 CDC42BPB CMTM3 CDC42SE1 NDE1 MPP3 ASAP1 NIP7 USP36 PLEK2 EPHA2 USP53 WDR43 PTPN12 CDCP1 GREM1 KLHL21 RAP1GAP EEPD1 PLK3 SHH FA2H MYEOV DBNDD1 FHL3 NOP56 RRP12 BRD9 LUZP1 SNAI1 MICAL3 SPRED1 LRRFIP1 FLNC VPS37B NES PCDH1 NAB2 AP1S3 ITGA3 TNFRSF10A PPP2CB KPNA4 PLIN3 GCLC GDA FERMT1 TXNRD1 MTAP HLCS PPAN EIF5A2 DYRK2 LRWD1 TNFRSF10B GPC1 CARD10 HK2 SETX PEA15 GPAT3 GPSM1 RBM38 MYBBP1A HNRNPAB MMP15 PLOD3 ANTXR2 ARHGEF2 FLNB DCBLD2 UBASH3B MFSD6 ADGRG6 SLC4A7 TNIK KCTD5 GTPBP4 ARID3B RASAL2 FGD6 AEN BICD1 SPIRE1 L1CAM TMEM201 PWP2 N4BP3 RHOF MICAL2 SHB CSNK1E AFAP1 MFSD2A DIP2B FAM43A VGLL3 PCDH7 ZNF697 RASGRF2 IFRD1 CAPRIN2 PPFIBP1 CLMP KCNK5 ARHGAP21 RASA2 SACS PFKP POLR3D NMD3 ZBTB7A DOCK5 CAPN15 ARAP2 LRCH1 MPRIP ST3GAL2 TMEM41B KIF5B ARPC5L CHIC2 PLD6 PDLIM7 RAB3B GPR39 SAMD5 SOX8 RNF126 ARHGAP42 SAV1 LYAR NIFK CD3EAP LCMT2 NSUN2 POLR1E RIN1 WNK4 NPIPB6 SPATA2L GPRIN1 GPRC5B RTKN YRDC GREB1L MLX FAM160A2 OSBPL3 UBE2F-SCLY TRABD2A NPIPA2 RFFL SLC35F2 500 genes down-regulated by SARS-CoV-2 in human Caco2 cells at 4h from GSE148729 untreated v SARS-CoV-2 Caco2 4h polyA GSE148729 down TICAM2 AMACR PTPN14 CEP350 GLYCTK TMEM37 TMPRSS2 UBD VDR NEK9 C1ORF115 SLC1A1 TOM1L2 UGT2A3 MPP5 ATP6V1A TYSND1 PRR15L CDX2 SEPSECS HOOK3 MAPK14 TTN MFGE8 EIF2AK2 FOXA1 TDP2 HHLA2 AKAP9 FRMD4B SRC MAP3K1 GOLGB1 SEPHS2 OVOL1 SMO NR3C1 TM7SF3 ZBTB44 MPP7 CABLES1 LIFR TMEM30A FZD5 N4BP2L2 HOXC6 MECOM SLC22A23 CFTR CEBPD RARB ERBB3 DUSP16 SLC40A1 FGFR2 ELF3 PKP4 PBX1 KIAA1217 PNRC1 TRIM2 SOX2 CDC14B C4ORF19 PRSS16 RGL1 SAMD12 SORBS2 CHST9 TPST1 ARID5B SEL1L SLCO2B1 THBS1 ARHGEF10L CIC SMAD7 NRP2 SLC6A6 MACC1 CEBPA FZD2 NEK2 DEPDC1B CLCN4 HMMR SPAG5 BUB1B ASPM AURKA BUB1 SLC1A3 BCAT1 EPSTI1 FAM72C KIF11 ACVR1B IDH1 KIF20A AKAP5 G0S2 AKR1C3 ABCC9 HINT3 BMP2 TRAM1 COL5A2 WDR72 ABCC6 TRAM2 BMP4 HNF1A EHHADH PLEKHH3 RARG ADGRF4 TPD52L1 RHOU BCL9 KITLG AXIN2 NAV2 NR2F2 IRF8 FZD4 SOX6 RGS3 SORL1 DGCR2 CREBBP SOWAHB RXRA KCNJ16 RBM47 CDC25C CREG2 ASF1B NSL1 DEPDC1 HMGB2 NDC80 CYP1A1 IFIT2 TMEM52B RNF213 ZNF711 GDF1 C1QTNF3 DPYSL2 TXNIP SMAD6 KLHL5 UBL3 SEMA3C JUND SP3 SAP30L MPC2 RTKN2 TNS3 MYLIP TCF4 CETN3 YTHDC1 NUCKS1 KIF26B OAT PDZRN3 LYPD6 TET1 ESRRG FILIP1L SLC2A11 NEURL3 IRF2BPL CDC42EP3 LIAS CFL2 CKB SDC2 SLC44A3 RFC4 CXXC5 TMEM245 CCDC117 FAM117A SOSTDC1 VAV3 PLEKHG6 SERINC5 ACBD5 GRB7 TNFRSF19 PIP5K1B PPM1H EFNA1 TMEM170B SAMD4A PIK3C2B PRR15 ID2 CEP192 LGR5 PHYHIPL NAALAD2 PCED1B C2ORF72 TOR1AIP2 DCP2 OLR1 AJUBA ARL15 RASL11A LBR ZNF439 MBNL3 ALG10B ARID4A SLC26A2 SMAD5 LRRC45 PDZK1 TIA1 GTF2I SYNJ2BP GLIS3 ASB8 TNRC6B PCYOX1 ZBED1 DIS3L P2RY1 SLC25A36 RCAN1 KLHDC2 SLC19A3 GALM PANK1 TM7SF2 MSRB1 XPO1 CDKN1B RBBP8NL HEXIM2 RCOR3 SESN1 SKIDA1 PDE7A BMF PIK3R3 GNE DPYSL3 PIWIL2 NCOA7 LRFN1 AKAP7 SKP2 MYCN FGD3 SP8 BCR FOXJ1 CDK6 NFATC2 PELI1 UGP2 UCK1 ADAM22 NXN ALAD CITED2 ALDH3B1 C5ORF15 ABHD4 EPHA4 HELZ ANKZF1 LRRC20 ARHGAP24 SOCS6 ZMYM2 PAPLN SYNE1 NEU4 PPP1R3B UNKL RHOBTB2 ZFYVE26 SLC37A4 TMEM129 REPIN1 TFEC AMOTL1 HBP1 DTX4 XPC EDC3 ITPR1 PRSS8 HNF1B LRP2 PITX2 CHDH TRPM7 TRMT1L ARID1A SEMA6A FOXP1 NCOA2 KMT2A TRIM24 MAGI1 SMLR1 ZBTB4 KDM4C SIPA1L3 CDK19 CHD6 PROM1 KRAS GCNT1 AMOT EHMT2 GALNT6 CNTNAP2 RNF32 DRICH1 TTPA SLCO1A2 FOXA2 DAPK1 CAMK2G PRR5 MAP1A TRPV3 KCNJ8 TMEM106B SESN3 SETDB2 RSBN1L SLC46A1 PCYT1B TRIP11 AP5M1 GBF1 SPTLC3 PPM1B PLA2G12B KLB SULT1C2 CYP2R1 DNAJC15 NR5A2 CCNG1 GATA6 SLC11A2 ACSF2 HDHD3 SLC35E2B FITM2 SH3RF2 MID1 UHRF1BP1 CNKSR3 KIF12 PKDCC PCYT2 GALNT10 B4GALNT2 PXMP4 UFL1 ZNF395 PUS10 UBN2 KLHL13 ZNF608 PHIP LMBRD2 NHLRC3 NTN4 ZNF703 CABLES2 FAM222A NR2F6 ELF1 TBC1D4 NECTIN3 BICC1 C12ORF49 PDZD8 KIAA0232 TMTC3 CHML LIMK2 DENND5B KMT2E CREB3L2 ZNF248 SOS1 EMSY RECQL5 CBX6 FAM168A CROT NADK2 RBM12B RASSF8 LYSMD3 ARMCX3 HOXA3 FRAS1 CCDC127 DAG1 SVEP1 ATP8A1 BMT2 LRP4 FAM126A PPIP5K2 ARHGEF17 LAMA1 DAB2 GAB1 ZNF652 ZMYM3 ARHGEF40 SORBS1 UMAD1 SLC25A12 ALDH5A1 AP5S1 FOXN3 PHLPP1 SMIM14 CADM1 RORA PSPH CCDC25 IPMK NPIPB9 SMTNL2 COA5 GABRA4 PPP1R12B AMMECR1 KLHL22 PLCH1 FBXO30 ZNF362 AGL JADE1 PLXNC1 CDKL5 ZBED3 RAB17 SNX27 PRMT7 INTS8 DDX52 CCDC141 BRD8 SYNRG TVP23C-CDRT4 ZNF519 C2ORF68 DCAF8 AMER3 DBT ARHGAP28 NUDT18 ZNF552 ARL17A MOCS1 DLEU7 GATAD1 TBX4 NMNAT3 RNF141 NSUN7 TCEAL9 LRRC8D NOL4L OARD1 MDM1 IGDCC3 DCAF16 GYG2 NKX1-2 PPP4R3B PAK6 PHEX C2ORF15 WWC2 PPP2R2B PRUNE1 AC011043.1 CACHD1 KAT14 CAB39L B4GAT1 500 genes up-regulated by SARS-CoV-2 in human Caco2 cells at 4h from GSE148729 mock v SARS-CoV-2 Caco2 4h polyA GSE148729 up F2RL1 STAT3 APC EGR1 MALL SPTAN1 FGF23 LARP4B YWHAZ ASAP2 MACF1 DAAM1 MYO1A BAIAP2L1 EPB41L1 CACNA1D TRIM15 TMBIM1 PRR15L ACSL5 NCL KLF6 TLE3 SMAD3 BRD2 SERPINE1 FRMD6 HNF4A GIGYF2 DNMT1 REG4 FN1 CRK SFN RETSAT MEPCE HERPUD1 MUC17 PXN STOM TGFB1 EGFR HKDC1 MUC13 FRMD8 PLEC PTK2 SPTBN1 LRRC8A MTMR14 RILP MCL1 CAV1 MYO10 CEACAM6 KRT18 ITGA2 ZNF532 KLF5 RGS2 TM4SF1 BMPR1B TTC9 MT-ND1 THRB PARD6B MTRNR2L8 GCNT3 SYTL2 MT-ND6 SH3RF1 COBLL1 S100A14 LMO7 C6ORF132 TNS4 FOXQ1 MT-CYB GPRC5A MT-ATP6 MT-ND4 TACC2 MT-CO2 DHRS9 STIM1 SRRT RELT PYGB MAN2B1 AQP3 LAIR1 USF1 IL4R SH3TC1 VASP AKAP1 NUMA1 FLNA LRP10 MYADM B3GNT7 EHBP1L1 HK1 ITGA5 TOLLIP RHOB NFE2L1 SDC4 CTSB MYO1E LDLR CTNND1 HDLBP DUSP7 MKI67 ARNTL2 SPTLC2 NKIRAS2 LRFN3 ARL4C FGFRL1 AKAP12 ADIRF PLCXD1 KLF16 B4GALT5 CDKN1A MYC ZFP36L1 MMP1 KLF13 GADD45B TRAK1 FGFR1 HMGA1 ACOX1 LAD1 CGN CLDN4 BCL9L DSP LAMB3 CAPN1 PLCD3 SEMA4B PPP1R13L ZNF217 ITPR3 SP6 CLU TFIP11 MMP3 TCF7 HNRNPH1 MAP3K4 EFNB2 STK40 C2CD2 SLC45A4 BCL3 NBEAL2 TRIM8 BRPF3 MNT OGFR MIDN ZNF710 SGSH RAD54B TRAIP TMEM45B PRSS22 APOL6 DPF1 NAV3 SOCS3 PARP12 SLC7A11 FOSL1 CD59 EHD4 ETS1 RPL28 ZFP36 LASP1 IER2 IER3 IGFBP4 ACTG1 MAP1LC3B IRF1 SGK1 EEF2 DTX3L JUNB TJP2 P4HB PDGFRA PRRG3 SH3BGRL3 HNRNPUL1 PLEKHG2 S100A16 ERRFI1 PHLDA1 SUPT5H RASSF5 MYO18A METTL14 DYNC1LI2 WASF2 ACYP2 PMP22 MFHAS1 SLC25A25 PPP1R15A SYP B3GNT5 ZNF267 ZNF841 HERC3 MUC5AC STC1 FLRT3 DUSP5 IRS2 FOXO3 IL11 FOSB ALAS1 MMP10 CIDEB MAGED1 GJA1 TNFRSF21 ARHGEF18 SERINC5 RHPN2 VGF HAMP ID1 ENC1 TAF7 SNX9 CEMIP C3ORF52 SIK1 PRRT2 ITPRIP ZBTB2 SMOX CDC42BPG INPP1 C6ORF141 SLC20A1 PHACTR3 LPGAT1 PLEKHA6 EIF3A GPATCH1 TNFSF13B GLG1 PRRC2C SCRN1 IGF1R LAMC2 EMP1 RNF145 ETS2 CEACAM1 ZNF649 DUSP4 GLUD1 PANX1 CFLAR ST6GAL1 HOXC9 TRIB1 CDC42EP2 FHL2 IGF2 DSC2 TUBB3 KRT6A ADAMTS9 SPRY4 TMEM214 C4B IFNGR1 ITGA6 PRKCD RAB35 SMN1 RIOK3 SH3BP1 GK PIK3CD CDK9 SOX5 MAP4K4 SPEN COPA TNFAIP8 STK10 SMURF1 TM9SF1 WDPCP KCNJ15 AHNAK CDC42BPB CMTM3 ZNF230 NDE1 TSPAN14 ASAP1 KIF13A EPHA2 KCNJ2 USP53 FGA DLL4 JRK ATXN1 PLEKHM1 VPS18 SHH PRODH PODXL AKAP13 MYO9B MAP4 LUZP1 SNAI1 FBXO31 MICAL3 DST LRRFIP1 FLNC VPS37B NES PCDH1 POLR3A ITGA3 ABHD17C RNF216 PLIN3 OTUD5 SLC5A3 GCLC APOB UGT1A10 SYT7 FERMT1 TXNRD1 SETD5 MBOAT2 PITPNM2 CYB5R2 TNFRSF10B PAK1 UBR4 HK2 FUT1 GTPBP1 SUCO POGLUT1 SAP30BP KAT7 GPAT3 HCAR1 WDR3 PRDM4 THOC5 ZNF282 DOCK8 PLOD3 ZNF142 DSE CSGALNACT2 ANTXR2 ARHGEF2 TMEM51 FLNB DCBLD2 TNIK SETDB1 MGA CNOT4 ARID3B RASAL2 FGD6 BRPF1 BICD1 MED13L SPIRE1 ABTB2 GPATCH2L RHOF MICAL2 SHB CSNK1E DIP2B SLK PCDH7 ZNF697 RASGRF2 CAPRIN2 ARHGAP21 ZMIZ1 KAT6A PPFIA1 HIPK1 GRAMD1A CNST DNMBP ZXDB HIF1AN STXBP5 PRKAB2 GPR161 NBPF26 DOCK7 ZNF562 JOSD1 MPRIP CUL9 ST3GAL2 ODF2 GSTT2 CHIC2 STRIP2 RBM19 C19ORF44 RELL1 CDR2L SOX8 UBALD1 ANKS1A GARNL3 FSIP2 TMEM92 PRR36 CNNM2 RUFY1 CD3EAP LCMT2 ZNF561 ZNF215 CDIP1 GNL3L RAB11FIP4 CHD7 POM121 FAM53C NBPF19 PTPN23 POMGNT1 GPRIN1 GPRC5B NIPA1 NR2C1 CHERP ZNF483 TSSK2 GPR89B GTF2H2C_2 SPDYE2 CTAGE8 HSPE1-MOB4 CNBD2 FAM160A2 TRIM33 UBE2F-SCLY ABHD14A-ACY1 NPIPA5 CERS1 NPIPA2 RFFL SFI1 AC145212.1 URAD RNF39 C16ORF87 ZFYVE19 KATNAL1 SCFD2 BAIAP3 MFSD9 CKMT1B NMNAT2 COL26A1 TOMM40L TMEM198 BUB1B-PAK6 LRRC46 CLDN11 ADGB SCN8A CLASP1 NIPAL2 500 genes down-regulated by SARS-CoV-2 in human Caco2 cells at 4h from GSE148729 mock v SARS-CoV-2 Caco2 4h polyA GSE148729 down SRP19 DCTPP1 PIK3R2 GLYCTK UBD FBXW5 CHPF SLC27A2 SLC1A1 TOM1L2 RNF2 PPT1 ANXA3 CYB5B AASS TSPAN8 MFGE8 EPS8L2 SIRT5 ACY1 FOXA1 PHB HS2ST1 TMED5 RNLS ARL14 CASP3 GGH TMEM236 NFS1 SEPHS2 LYPLA1 TM7SF3 BPNT1 FAHD1 CABLES1 TMEM30A WDR34 PAIP1 TGDS SLC25A16 FZD5 N4BP2L2 C20ORF27 PSMA2 BTF3 POLR2B MIF4GD PERP DDAH1 UQCR10 RHOBTB3 TRIM2 PITX1 EPCAM CKS2 GSTA1 COX7C RPS29 CHST9 TPD52 MYO5C RPLP1 SLC12A9 TOMM40 THBS1 TM9SF3 NDUFB5 MACC1 SCARB2 CREG1 POMP MGME1 CLCN4 HMMR ATP6V1F FH SDHD AURKA SHMT1 SLC1A3 BIRC5 PDSS1 BCAT1 MYDGF CDC45 ITGB8 AKAP5 MYBL1 LINS1 ABCC9 SLC2A9 HINT3 BMP2 TRAM1 SLC2A3 COL5A2 SLC2A8 BMP4 CYCS DNAJA3 RHOU KITLG RAB4A TMEM60 DVL2 FZD8 SORL1 UBE2Q2 SOWAHB PDLIM5 ERF UBE2T MIS18BP1 ASF1B GINS2 ARHGDIB RACGAP1 ZWILCH MAD2L1 HMGB2 CENPH RAD51AP1 CYP1A1 DNPH1 COCH DHFR NFKBIE ADM PPA1 MITD1 ZNF704 GDF1 SHANK3 TXN SYF2 ANAPC13 UBL3 CLIC5 AGER SEMA3C GNG10 GABARAP PSMB6 SLC12A2 JUND NDUFB3 PCNP LRRC58 OAZ1 ADRM1 TRMT112 MRPL28 MPC2 FEZ2 CAPZA2 ANXA1 TCF4 C1ORF198 SUB1 NUCKS1 DBI DEK HSPA6 TMEM14B PAH TTR AMOTL2 CDC42EP3 DPY30 PIGF ATRAID MAGT1 UBE2S LIAS SNRPG UBE2M TMEM243 MIF CFL2 GALNT7 TEX30 DYNLT1 AMZ2 MRPL42 ARFIP1 VPS72 TSPAN4 PCNA THYN1 COMMD8 SLC44A3 MOB4 LACTB2 NAA50 CXXC5 PNPT1 MRPS30 GMNN C15ORF61 ITGB3BP TMEM50A SNX10 HSPE1 EBPL NDUFA9 SNRPE SF3B5 C1ORF122 TAX1BP3 RPL34 CCDC117 FAM117A HSPA4L KHDRBS3 ANKRD1 MNS1 ORAI1 ID2 NARF DIAPH3 LGR5 RWDD4 HSD17B14 MUL1 TRIAP1 SLIRP C2ORF72 BID TMEM212 LRRC23 KLHL6 C19ORF25 OLR1 AJUBA POU6F2 LIN28B ZNF791 C22ORF39 RFC5 GALNT12 LRRC45 SCOC ANKRD49 KBTBD6 SMIM10 CRIM1 TPRA1 YTHDF3 CEP290 SCAMP1 SLC25A36 LIMA1 NFE2L3 NCEH1 TMEM62 BLVRB UQCR11 SERP1 CALM2 ADAM10 SPTSSB PDE7A BMF CENPV CHKA NCOA7 LRFN1 TAL1 HIKESHI GLRX3 TWF1 ANAPC11 PSMG2 VPS29 ANAPC10 PFDN4 RPE FGD3 CDK6 PELI1 MRPS12 SF3B6 KPNA5 COX20 COQ4 CRLS1 ZNF665 TPM1 NXN CITED2 CMAS AURKAIP1 ARF4 CGGBP1 C5ORF15 DEGS1 NUBP2 PHC3 TBX19 LRRC20 WDR75 SOCS6 SLC39A8 GTPBP10 HSPB11 MRPL33 NUDT14 METRN RNPEPL1 NOX1 TMEM129 REPIN1 CMC2 PARVB PRSS8 CD320 ZBED5 ECEL1 CEL TRMT1L KDM4C DTYMK THUMPD2 PGP ORMDL1 UGT1A1 STK11 APOA1 TRPV3 VAPA KCNJ8 TMEM106B FANCF SLC46A1 ELMOD2 GCSH GCLM PPM1B POU2F1 GLTPD2 LMO4 DFFB GLS2 TMEM138 ZMYND19 PIH1D2 MRPS34 LATS2 TMEM59 PLA2G4B DTNA TMEM70 JOSD2 RMI2 DUT PKDCC GALNT10 POLR3K RIBC2 ELP6 B4GALNT2 UFL1 LCA5 PTAR1 SSX2IP PGRMC2 RSL24D1 SBF2 PYROXD1 AGTPBP1 NTN4 ZNF771 HSPBP1 NR2F6 LGR4 ELF1 BICC1 COMMD2 USP38 PDZD8 TMTC3 CHML FAM217B TMED1 MLST8 EIF3CL BRF2 LSM5 GOPC TMED7 SOS1 MICU3 CDK14 ATPAF2 PPP1R2 ERGIC2 PYURF FANCL HIGD1A TMEM38B SLC25A17 CROT LAMTOR4 BPHL SLC7A2 HOXA3 CCDC127 DCDC2 BIN3 SPRYD7 NTPCR CUL5 G2E3 CXADR ARHGEF17 DIMT1 PDXP SLC25A24 HNRNPLL NUP35 LDLRAD3 NBAS TCFL5 AP5S1 AATK ZNF511 DOLK MRPS24 NUDT4 CRCP SRBD1 IPMK MKS1 SMTNL2 COA5 DUS1L PAM16 GCFC2 AMMECR1 ACD ZNF43 FBXO30 AGL ME3 JADE1 SPATA6L MEX3D RAB17 NBPF6 ST20-MTHFS RPP21 PSTK MRPS31 GATC INTS8 SMIM11A NME1-NME2 BLOC1S5-TXNDC5 MCRIP1 ZNF709 MDP1 BSCL2 CTAGE4 ANKHD1-EIF4EBP3 DBT ZNF528 ARHGAP28 SMN2 ARL17A P2RY11 RBM14-RBM4 AC012314.5 AC012314.3 CKMT1A AC012314.4 AC012314.6 SULT1A4 GTF2H2C GATAD1 LRRC8D PPP4R3B AC011043.1 KAT14 LRRC37B PTPRG COA1 SCLY BAG2 TMEM18 CALML4 ALG13 PRSS35 TMEM267 C4B_2 IGSF1 CBR4 ZNF846 CPSF4 LBHD1 500 genes up-regulated by SARS-CoV-2 in human Caco2 cells at 24h from GSE148729 mock v SARS-CoV-2 Caco2 24h polyA GSE148729 up F2RL1 PTPN14 BCL2L1 RSRC2 BIRC3 XPO6 EGR1 SQSTM1 FGF23 BCAR1 DDX21 MACF1 MIPOL1 ACSL5 RUNX1 ZNF274 KLF6 NUP58 BRD2 SERPINE1 FRMD6 SNIP1 TP53 PDE4D SFN SDE2 FBN2 SLC16A6 CXCL2 FERMT2 ARL14 PLEC LRRC8A RBM39 ARHGAP18 MCL1 KRT18 ITGA2 ZNF532 KLF5 RGS2 TM4SF1 HES1 GULP1 MT-ND1 PARD6B MTRNR2L8 SH3RF1 NFAT5 ELF3 RASSF6 TNS4 MTRNR2L12 MTRNR2L1 FAM214A SLC2A1 GADD45A RND3 ANKRD33B PRDM1 OTUD7B FMN1 BDP1 GPRC5A SIX4 CEP170 MT-CO2 ZBTB20 ZNF462 CCND1 MDM2 FLNA MYADM RHOB ZYX ARHGAP31 ZBTB43 AREG LDLR ARHGAP29 STARD13 MAFG SPRY2 TMEM45A ARHGAP23 NRIP1 CXCL8 PTGS2 AKAP12 MYBL1 MYC ZFP36L1 KLF10 KLF11 GADD45B AXL FGFR1 EDN1 PLAUR MITF FAM83G SLC7A5 ZNF217 EREG PRICKLE2 SOX9 DLX2 ATF3 JAG1 EFNB2 TCF7L2 UPP1 TRIM8 NUAK2 PLEKHG3 SBNO2 MIDN COLEC12 TKTL1 KCNJ3 ZNF442 CYP1A1 CXCL3 SLC4A1 NAV3 VCAN TINAGL1 NFKBIE ADM SLC25A22 FOSL1 IRGM PLAU AHR ETS1 KLF4 ZFP36 IER2 IER3 FOS IGFBP4 ACTG1 IRF1 RASGRP3 DUSP1 TXNIP ICAM1 NFKBIA CDC42EP1 JUNB RAPGEF2 JUN TJP2 PDGFRA HLA-DQA1 NUPR1 ARRDC3 VIM ESAM PIM3 ERRFI1 CCNL1 ANXA1 PHLDA1 NRP1 YTHDC1 FSCN1 SLC38A2 GEM ADAM32 KIFC3 ZC3H12A DDIT3 DUSP8 SLC25A25 TBX3 TRAF1 NR4A3 PPP1R15A SYT1 LHX6 DCUN1D3 TNFAIP3 SOCS2 HDAC9 ASB2 ZNF35 RUNDC3B ZNF267 ZNF292 PLA2G4C FILIP1L ZNF554 AMOTL2 DUSP6 PPP1R15B LIF DUSP5 IER5L IER5 TIPARP YOD1 CSRNP1 ZSWIM6 CLCF1 BHLHE40 TAF1D MAFF NFKBIZ TSC22D2 SERTAD2 ZNFX1 FOXO3 IL11 FOSB VMP1 TNFRSF21 TMSB10 DHRS2 AGPAT5 RLF MXD1 ZNF317 ODC1 RHPN2 VGF KLF7 ANKRD1 ID1 ENC1 CREBRF HIVEP2 MOSPD1 REL ABL2 JSRP1 AVIL TOR1AIP2 INPP1 CASS4 PRPF38B LIN28B PER1 ZNF791 PHACTR3 TNFSF13B BCL10 CCNT1 TOP1 LAMC2 EMP1 PPP1R10 ETS2 PLK2 AFF4 RELB ETV7 CPEB2 NFE2L3 DUSP4 NCEH1 RBMS2 C1S IRS1 CFLAR XPO1 DYRK1A LPAR6 PPTC7 HRH1 TRIB1 FJX1 PHLDA2 CLK1 FHL2 NR4A1 TNFRSF10D TUBB3 KRT6A NR1D1 SPRY4 ETV3 NWD2 ANGPT2 IFNGR1 ITGA6 DHX36 MASP1 COLEC11 ZNF655 SPEN SPRY1 NFKB2 KPNA5 CYLD SMURF1 MTRNR2L6 C12ORF45 C12ORF50 BHLHE41 POLR3G USP36 ZNF14 EPHA2 ZBTB10 NSRP1 GPCPD1 RBBP6 DNTTIP2 ZNF430 WDR43 DNAJC2 BRIX1 CCNT2 RIOK1 GREM1 KLHL21 SYNE1 PLK3 TET3 MIER1 FHL3 SSH2 EPC1 ELK3 TSPYL2 SPRED1 FLNC ITGA3 RIPK4 PER2 LIG4 E2F3 KDM6A GLIPR1L2 KMT2C JMJD1C FERMT1 ZBTB21 CHD2 EIF5A2 TNFRSF10B SPRED2 GPC1 PROX1 FAM133B ZFAND5 FBXW7 MT-ATP8 HK2 RC3H1 ZNF202 ZNF627 ZNF800 RSC1A1 ZNF398 SUCO SETX TGIF1 GPAT3 UGCG NR5A2 SOX4 UTP15 PRDM4 LATS1 LATS2 MTRNR2L4 CYSLTR1 DCBLD2 UBASH3B SLC4A7 USP42 POGZ NOP2 ZC3H4 PIP5K1A LYST MED26 SPATA2 ZNF335 MGA NOL6 LETM2 GTPBP4 ARID3B RNF111 ZNF77 RASAL2 WAC INO80 FGD6 AEN ZFX SPIRE1 FEM1A ZSWIM4 SKIL L1CAM APOBEC3D HIVEP1 THSD1 ISG20L2 AFAP1 REV3L LCA5 ZNF608 NABP1 KDM5B ZC3H6 IFRD1 FRS2 ZNF131 HNRNPDL CAMSAP2 KAT6A VEZF1 USP38 SVIL OPHN1 ALOXE3 RNF103 TRIO KMT2E BAZ2B LCOR PCF11 CWC25 NOCT MAK16 STRN3 FBXO38 FOXN2 RBM5 EMSY ARID4B ZNF441 CPEB4 FRYL ARAP2 ZNF264 LRCH1 FGFR1OP2 PLD6 FAM126B ZNF121 ATAD2B ZNF557 RBM48 ZNF92 ZNF57 INO80D RASSF9 RLIM ZNF555 RAB3B RABGGTB PALD1 FAM193A LYAR CD3EAP KDM7A CLK3 NSUN2 SLMAP TNXB MED17 UNK WNK4 PGM2L1 GATAD2A GPRIN1 PINX1 CCDC59 USP47 PIEZO2 TPH2 YRDC GREB1L SMIM11B FBXW10 ZNF625-ZNF20 UBE2F-SCLY ZNF556 ZNF844 MYLK3 ZNF585B KLHL31 MAP7D3 NWD1 ERCC6L2 C1ORF61 IL1RAPL1 C1QTNF3-AMACR FAM153B ZNF101 ASB3 DCAF4L1 GSG1 LEKR1 500 genes down-regulated by SARS-CoV-2 in human Caco2 cells at 24h from GSE148729 mock v SARS-CoV-2 Caco2 24h polyA GSE148729 down ANO9 AMACR UBB EEF1A1 FCGRT OS9 DPP4 GLYCTK COL6A1 TMEM37 TMPRSS2 SPINK1 ETFA PRKACA DGAT1 C1ORF115 SLC27A2 SLC1A1 CDH17 SLC9A3R1 UGT2A3 RBL2 SLC7A7 ACE2 VIL1 AHSG TMBIM1 PFKL FABP1 NBR1 PRR15L COL4A1 XPNPEP2 CDX2 NDRG1 CRYL1 ST14 VILL CDHR5 GGT1 GPAA1 AMN HNF4A CALM3 ACAA1 HEPH COPB2 ING4 AGT B2M TSPAN8 MFGE8 ERBB2 RETSAT EPS8L2 USH1C MUC3A TDP2 PEPD DHRS11 MEP1A KRT20 PLS3 EPHX2 SRC GUCY2C DCAF7 REEP6 GGH PIGU NEU1 SLC39A5 DHTKD1 SFXN5 SEPHS2 TSR2 SAT2 ADH5 SCP2 ACBD4 METTL7A ALDH6A1 NDUFV1 ACO1 PSMA2 ALB TFF3 AK4 FAM114A1 CFTR ERBB3 SLC40A1 FGFR2 S100A14 PBX1 CA8 TRIM29 TFF1 GSTA1 AGR2 STARD10 TSPAN3 TAGLN2 ATP1A1 MAN2B1 TMBIM6 SLCO2B1 PTPA UQCRC1 ARHGEF10L DHRS7 GSN H6PD AP1M1 CORO1B GPD1 LRP1 NDST1 GANAB NRP2 GRN ABCC3 SLC6A6 ABHD2 SLC38A10 DHCR24 CEBPA SCARB2 CTSB CREG1 HSD17B4 STS OPN3 ACCS SDHD HADHB SLC1A3 EPSTI1 FAM72C LGALS3 ACVR1B CLDN7 FAM20C IDH1 SORT1 KIF20A G0S2 AKR1C3 A2M SPON1 TJP3 PBXIP1 TSPYL1 CDSN TRAM1 COL5A2 MAVS APLP2 MMP11 TF EHHADH NECTIN1 TMC4 SLC26A1 MYH14 CLDN3 TPD52L1 WLS NR2F2 FZD4 CD63 SORL1 TMEM164 RAB11FIP3 RXRA RBM47 DDR1 SOAT2 QPRT CFB NCAPD2 KNG1 TMEM45B DNPH1 C3 DHFR HERC6 HMGCS2 FGG SLC39A14 SLC3A1 DDC PSME1 FTH1 SHANK3 TSPAN13 LY6E AKR1A1 THRA HMGCS1 GSTP1 DAZAP2 CTSH ALDH1A1 COX8A GLUL SAP30L CALR PSAP MPC2 MXD4 SELENBP1 GNS GM2A KIF26B MEGF8 HAUS4 OAT S100A10 CD9 BNIP3L PDZRN3 APOH FGB LYPD6 GSTA2 TTR SLC2A11 LGALS2 RRM1 ATP6V0E2 TMEM205 CKB GPR160 MAGED1 SDC2 TMEM14A TMEM230 PI3 HAVCR1 TIMP2 PAM SLC44A3 TMEM50A RPN2 ETFB LDHB CPN1 HSD17B11 VAV3 PLEKHG6 SERINC5 ARL6IP1 APOBEC3C PGM1 HACL1 CPNE1 REEP1 PHYHIPL TMEM200A F10 HSD17B14 MVD C2ORF72 ATF6B TDRD7 ARL15 RASL11A FGFR3 RGN CTSV DUSP9 BBS2 ASRGL1 SLC26A2 PDZK1 APOBEC3B CNNM3 PAQR8 PCYOX1 ZBED1 PAPSS2 UGT1A6 GPT2 COPG1 GLUD1 KLHDC2 PMM1 GALM SERPINA6 TM7SF2 SERPINA1 UQCRFS1 ST6GAL1 RBBP8NL SESN1 P2RY6 SLC25A42 IGF2 APOE LAMA3 SCGN ADH6 AKAP7 C4B PGK1 SKP2 ORMDL3 FGD3 UGT2B7 HFE ARRB1 ERP29 PLEKHB2 GBA USP5 RAB5B PHGDH PI4K2B GSTK1 ADAM22 VTN SUCLG1 CMAS CNPPD1 CLN3 ALDH3B1 ACAA2 ANXA4 RPL17-C18ORF32 MANSC1 ABHD4 TSPAN1 RBP4 ERAP1 EIF2AK1 C4BPA FGA PMF1 OBSL1 HTT ADI1 NEU4 HAPLN3 ABCB6 P2RY2 PRODH COL27A1 KLC4 SLC37A4 TMEM129 TPP1 ILVBL SLC39A7 DTX4 PRSS8 LRP2 APOC3 APOB SREBF2 ZG16 SEMA4G SMLR1 SLC37A1 GCNT1 AMOT CCNG2 DAPK1 CYP27A1 PAK1 APOA1 KCNJ8 SLC35B3 EXOC3L4 ABCA2 GPC3 PCYT1B SPTLC3 SULT2A1 AKR1C2 ORM2 CPT2 PLA2G12B HGD HAAO SERPINF2 GJB1 SLC29A4 AKR1C1 GLTPD2 SULT1C2 CYP2R1 FAM151A CRAT SULT1C4 DNAJC15 HDAC10 MGMT CCNG1 AFP SLC11A2 TMEM59 UGDH PNKD ACSF2 NYNRIN BCAM ANXA9 ANAPC16 KDELR2 FBXO2 FITM2 HACD3 NIPSNAP1 MAGED2 TMEM141 SLC25A1 EBP CARHSP1 B4GALNT2 PXMP4 ZNF395 ESPN KLHL13 RAB15 ZNF488 NTN4 C1QTNF6 CABLES2 HGSNAT CDK18 TMEM187 ECH1 KREMEN1 DCAF11 GPR161 BEX3 TMEM9 WBP1 SNTB1 POLR2J2 CROT LAMTOR4 SCRN2 COL2A1 ARMCX3 FRAS1 SND1 HIC2 SEMA6C NECAB3 IL17RE RALGPS1 LAMA1 ALDH18A1 CCL15 ZMYM3 MFSD10 PLPP1 RAB11FIP4 SPPL2B SMIM14 CADM1 PSPH ARID3A TMEM106C SMTNL2 WDR6 MTMR4 CLSTN2 PLXNC1 ABHD15 PCED1A SLX1B SYS1-DBNDD2 BLOC1S5-TXNDC5 D2HGDH AC012314.5 AC012314.3 AC012314.4 AC012314.6 TBX4 NOL4L GYG2 NKX1-2 PHEX PRUNE1 SCLY CALML4 PRSS35 NPTXR TSNAX-DISC1 GPC5 ALPK2 MKRN2OS HSD3B1 LRRC75B SPDYE5 MAN2B2 SMUG1 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 untreated v SARS-CoV-2 Calu-3 4h totalRNA GSE148729 up SRP19 F2RL1 RPS27A IL1B EGR1 MDN1 FGF23 PTPN3 DDX5 PKP2 DDX21 MACF1 UPF1 RNF24 BAIAP2L1 TLR4 TRIM15 NDUFAF2 CDHR5 FRMD6 PTX3 VSTM4 CXCL2 NUP98 IFNB1 EGFR FERMT2 UAP1 PLEC CHD1 RABEPK RIOK2 AFAP1L1 MCL1 MYO10 KRT18 ITGA2 RGS2 ALMS1 NT5E RAI14 TPT1 RNF152 TNS4 SERPINB2 ZNF460 RPS29 CEP170 RPL11 DHRS9 CCND1 RPL27A IL4R GSK3A ZNF316 THBS1 SH3TC1 HBEGF MYADM NRP2 ABCC3 PNP AREG DDIT4 HCCS VDAC1 FKBP5 SERPINB10 CAPNS1 SIGLEC11 PPARGC1B GLDC DUSP7 FAM89A MTHFD2 ZNF365 MPP6 CXCL8 ZNF600 AKAP12 KLF16 B4GALT5 CDKN1A MYC MMP1 CDV3 PLAUR SEMA4B IFFO2 FAM83G ITPR3 IFNE EREG PRICKLE1 DKK1 FOXL1 JAG1 MAP2K3 HIF1A STK40 C2CD2 DYRK1B PHC2 RAB43 CAMK4 CCL20 CD160 LANCL3 ENPP6 CD274 MLKL HAS3 JPH3 SOCS3 NAMPT INHBA FOSL1 F3 ANGPTL4 PLAU FST LRAT EHD4 ETS1 KLF4 IER3 IGFBP4 HPCAL1 ARL2BP JUN FABP5 MAT2A ADAMTS15 BMS1 ERRFI1 PHLDA1 EFHD2 MSANTD4 NRP1 CREB5 MBP IFNL1 TCF23 LONRF3 TNFAIP3 TMEM150C STC1 GPR157 CALB2 TBC1D30 DUSP6 LIF DUSP5 IER5 TIPARP CSRNP1 SERTAD1 BHLHE40 PFKFB3 IL11 SLC25A33 SH2B3 SOWAHC SEH1L DNER PPP1R18 TMEM185B PUS7 ADSL PITPNB ETF1 USO1 GEMIN5 MORC4 ODC1 TAF4B SRSF7 ENC1 MAP1B SRXN1 TAF7 GSPT2 RPIA CEMIP SLC35G2 RASA1 URB2 PSD3 TATDN2 KCNJ11 MARS2 FAM161A NEU3 ATP6V0D2 INPP1 OTUD6B IFNL2 TTF2 SLC20A1 LONRF2 SLC26A2 ZNF257 NPIPA1 PPIL1 CT83 ZNF302 RPL22L1 ADRB2 ST3GAL1 ZNF573 UTP20 POGK FUT8 EMP1 TGS1 ETS2 ZNF649 DUSP4 B3GALNT1 CHSY1 ZNF177 RIMBP3 FLI1 PTPRE TRIB1 CDC42EP2 PHLDA2 OSGIN1 MBLAC2 SLC25A32 SEC14L2 SEMA7A CXCL14 LAMA3 TNFRSF10D ADAM19 STK32A ADAMTS9 SLC6A14 GNA12 ITGA6 NXT1 AGO2 EIF2AK4 MAP4K4 CXCR4 SPRY1 OTUB2 IFNGR2 ATP2A2 ARCN1 PWP1 SEC16A SMURF1 TBCCD1 BLOC1S2 CDC42SE1 POLR3G TSPAN14 CHST10 USP36 ZNF41 ZNF587 PLEK2 EPHA2 ZNF8 LTV1 GPCPD1 CEBPZ WDR75 WDR43 CDCP1 PPAT CAMKK1 KCNC4 PLK3 CHST3 ASB1 FHL3 NOP56 CCM2 AMOTL1 CTPS1 SSH1 PLXNA2 AFG3L2 HMGA2 PUM3 TNFRSF10A ABHD17C RIPK4 UBE2Q1 SLC7A6 GRK5 PRKCE NOS1 ECE1 NPAS2 TGFA CLCN2 E2F3 FERMT1 CBL GCNT1 SYNJ2 EIF5A2 TNFRSF10B MREG CARD10 HK2 ZNF202 ZNF283 RSC1A1 BCL2L2-PABPN1 ITGAE RAB7B AP3M2 ANKLE2 SUCO CYP2W1 GPAT3 MCPH1 ERN1 GALNT14 DFFB SIAH2 LPAR2 NEIL2 RBM38 WDR3 QTRT2 PRMT3 UTP15 THUMPD3 XPO5 GEMIN4 MRPS34 RRP1B MAP2K4 ANTXR2 ARHGEF2 DCBLD2 UBASH3B SEL1L3 SLC4A7 PCNX2 KLHL18 NOP2 MGA ZBTB9 ZNF280C GTPBP4 ARID3B C1ORF109 AEN ZBTB24 BICD1 ZNF473 SRFBP1 C18ORF25 DLC1 SLC25A37 TMEM201 ISG20L2 RHOF MICAL2 FAM83A CDRT1 LGALSL DIP2B FAM43A ZNF607 NCR3LG1 RASGRF2 CAPRIN2 INTS5 PDE3A GFOD1 ICE1 ZNF131 SACS ZNF275 NLE1 PDLIM4 EIF3CL ZNF778 DNHD1 CNST CCDC174 DNMBP MAK16 FAM86B1 ZNF239 RGMB SLC25A30 PADI1 OTUD4 RAPGEF6 NDUFC2-KCTD14 NOP16 DOHH PRR14L GTF2H4 ZNF587B ZNF562 PHKA1 FUBP3 JOSD1 LRCH1 ZNF112 ODF2 ARPC5L CEP85L ZNF614 MAMLD1 SHC4 CARNMT1 LSM6 KCTD13 ARHGAP26 RABGGTB PDP2 C2ORF42 NIFK ALKBH2 CD3EAP ZNF561 POLR1B CMC4 DDX51 RIN1 ARID3A TACO1 DCBLD1 NPIPB9 NBPF19 SUSD4 CHGB LRP12 CRYBG3 PAK1IP1 MAP6D1 TSSK3 TRIT1 POLN DENND1A COMMD3-BMI1 ZNF595 ST20-MTHFS ZFP69 TRMT5 YRDC FAM227A AMER1 SPDYE2B POLR2D ANKRD20A1 SMIM11A EEF2KMT DDX31 MLX POC1B-GALNT4 HSPE1-MOB4 ZNF343 NPIPB5 CNTNAP3B ZNF843 POU5F1B U2AF1L5 ANKHD1-EIF4EBP3 KCNB1 PPEF2 ATCAY CDRT4 BIVM-ERCC5 SPECC1L-ADORA2A DZIP1 FAM156A NPIPA8 ZNF525 GTF2H2C C12ORF56 MAP7D3 ZNF589 RGPD8 TMC7 ZNF586 ERVFRD-1 LY75-CD302 IPPK SPDYE11 SCMH1 BEND3 BAHD1 NRSN1 ANKRD44 KCTD14 ST8SIA3 TYW1B ZNF696 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 untreated v SARS-CoV-2 Calu-3 4h totalRNA GSE148729 down AMACR UBB RTN4 NBL1 FCGRT OS9 SLC17A4 UBD MAP1LC3A LMAN2 MME UBE2D3 DAAM1 ACE2 IFITM1 NBR1 PRR15L NDRG1 HLA-B CENPF UBE2D1 HSPB1 GGT1 ABI1 TUBA1A RAB18 OAS1 HLA-DRB1 ING4 HLA-C CYP2C18 HLA-A IFITM2 AGT MUC3A ITM2A PHB NEDD8 TRIM31 HHLA2 MAT2B SIL1 ISG15 APP UBQLN2 RAB10 ARL14 MX1 CREBL2 SLC25A40 VAMP8 CLDN10 DHRS1 RCAN3 CAV1 DDAH2 SERPING1 TNFSF10 PIGR RARB RAB40B ERBB3 FGFR2 MT-ND1 RPL41 GPX2 ELF3 PBX1 SPAG16 PNRC1 CCDC80 MARCKS WFDC2 TCP11L2 PTGFR FAM214A COX6A1 SCIN SORBS2 EYA1 MBNL2 GCNT4 TPD52 STARD10 ZBTB20 ARID5B CHCHD10 VTCN1 ARHGAP30 TMBIM6 ARHGAP4 STMN1 NUMA1 GRINA FKBP8 GIGYF1 CYBA CORO1B APOL2 HLA-E TMED9 TK1 CAPG FZD2 NDUFS7 FAM72A LGALS1 MCM2 ASPM RNASE1 KIFC1 ROGDI SNX3 BRCA2 PRDX3 IKZF2 CA11 MIB2 CRIP2 AKR1C3 CDKN1C TCN1 PBXIP1 TFDP2 TRAM1 PLCXD3 BAD PIK3IP1 TRAK1 ENAM MITF ANXA8 ANXA8L1 MEF2C RHOU TMSB4X TMEM60 FGF12 TNFRSF11B CASZ1 SAA1 MIS18BP1 CFB STAG3 MS4A6A NUSAP1 ARHGDIB HMGB2 NDC80 CENPE MYO1F CYP1A1 MB RTP4 CDT1 HLA-F TREX1 HERC6 LGMN STAT2 RAMP1 TREM1 GBP2 IFI35 PARP14 ATP13A4 INMT TTYH3 SHISA5 TMA7 CAPZB TPPP3 SMAD6 ATP6V0E1 PSMB9 SH3BGRL ITM2C HLA-DQB1 BTG1 LYZ SNRPD2 PDE5A NDUFA13 VPS28 LAPTM4A GLUL JUND EID1 TP53INP1 MBNL1 SRP14 NDUFA5 NDUFB7 NDUFA2 ROMO1 PSAP KLHDC3 MPC2 SMIM22 MXD4 PIGQ TNS3 HLA-DMA SAT1 MARCKSL1 NDUFC2 CD164 PGRMC1 NDUFA7 SLC38A2 MIEN1 BNIP3L PRR16 HDAC9 ZNF292 CLSTN3 FILIP1L IRS2 DPY30 UBE2A MAGT1 PDZK1IP1 TM4SF4 WBP2 S100A11 CRYZ MIF DCXR YPEL5 RABAC1 LAMTOR5 SRP9 PSMD10 ZMAT2 PHLDA3 NOSIP WDR54 SERINC1 NAA50 GMNN AKR1B1 STAG2 TMSB10 SNRPE CUEDC2 SPSB3 RB1CC1 PCSK5 VAV3 SERINC5 GRB7 TMEM47 APOBEC3C MNS1 AKR1B10 CREBRF MSMO1 TMEM139 KLHL24 ZBTB22 RNFT2 JSRP1 TAPBPL PDK4 MUC20 ZCCHC18 AJUBA PTMS CYP1B1 HLA-DMB FXYD2 IFI6 SYT16 DIRAS3 GMCL1 LAMB2 GBX2 LGALS9 SCOC C1ORF210 NPY1R PMM1 MDK C1S PLSCR4 RABGAP1L SERF2 MSRB1 COPE COX5B SERP1 RBBP8NL UGT2B15 SKIDA1 MEX3B THAP2 BMF CCT6B ONECUT1 TRAPPC3L APOE DSC2 PTPRR SFTA2 CCDC34 ZDHHC1 PET100 RNF5 NAGK LILRA6 ARL2 GBA USP5 TOM1 FKBP3 NR1H2 ARPC5 OTUD1 SPP1 RNF181 SZRD1 CES3 AP5Z1 CALCOCO1 CITED2 ASAH1 COMMD1 ACAA2 ABHD4 ANKZF1 ZBTB10 ARHGAP24 MZT2B HDAC5 UNKL AMDHD2 MBD3 ZFYVE26 ALDH16A1 BCL6 NEXN YPEL3 AGMO CYSTM1 FLOT1 NFATC4 HBP1 MAF1 UNC45A MTUS1 MMP7 YIPF2 CDKN2A SEMA6A OVGP1 NCOA2 SLC44A4 HIP1R SH3GLB2 FXYD3 SLC2A12 AMOT SRGAP2 DAPK1 CCDC85A EIF4EBP1 ZACN GOLPH3L APAF1 SESN3 MTHFS ULBP2 ABTB1 UGT1A3 AP1AR GJB1 BAAT RIDA LMO4 CBLB SGPP1 LNX1 HOXB4 ATF2 SOX4 CCNG1 PIN1 TCEAL1 POLD1 TMEM59 RNASEK NAPRT ACSF2 JOSD2 NYNRIN PALMD BCKDHB HECA CSN3 GPC4 LRRN3 CAPS COMMD4 KIF12 PKDCC SLC22A18AS SDR39U1 PGAP3 DPY19L4 DCUN1D1 FAT4 PGRMC2 FAM171B ZNF488 TES NTN4 TECR C1QTNF6 HSPBP1 GPRIN2 RAD9A LGR4 CREBZF RAB27B ARPP19 MACROD1 NAA38 WDR18 ZMAT5 TJAP1 ZNF75A KYAT3 BCKDHA BEX3 ALG1L WBP1 MGAM2 PEX13 ZNF85 DUSP23 APBB1 FAXC IQCK CENPQ CACNG4 PCMTD1 ADGRL3 ENSA SCAMP3 ANKRD2 KLHL3 PGM2L1 ZFPL1 TMEM132A CCDC103 GHDC DTNBP1 CDKL5 NPHP3-ACAD11 C19ORF73 SYT15 DLGAP3 CECR2 ISY1-RAB43 BBS1 BRD8 NPIPA7 SMIM11B SPDYE2 CTAGE8 TMEM189-UBE2V1 CXXC4 PRRG2 PRSS33 SLX1A PPAN-P2RY11 AP1G2 ZNF493 SULT1A4 C9ORF135 HNRNPA1P48 GJA9 TMEM42 LRRIQ1 MAML2 CIR1 CLEC18A FAM151B FIBCD1 CFAP52 CCDC8 CT476828.5 KLHL32 MFAP2 NECAB1 FOXD4 FAM180B CT476828.21 PCDHGB6 SHANK1 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 mock v SARS-CoV-2 Calu-3 4h totalRNA GSE148729 up TICAM2 NUP210 ATP6AP1 EGR1 MDN1 LARP1 PTPN21 CACNA1D MYO15B GOLGA3 SLFNL1 CDHR5 RUNX1 KLF6 TTN FRMD6 VSTM4 ZNF318 IFNB1 EGFR PLEC RCOR1 MAPK1 ERC1 ARHGEF12 SIAE MYO10 PCLO ITGA2 KCTD1 MTRNR2L8 RAI14 NFAT5 USF3 KIAA1217 TNS4 HUNK MTRNR2L12 QSER1 ZNF460 C1ORF116 MT-ND4L EYA4 CEP170 ZNF462 MDM2 SYMPK MYO1G LAIR1 GSK3A ZNF316 THBS1 H6PD PCNX3 MYADM KHNYN NAIP ACCS CAPNS1 PPARGC1B ARHGAP23 AKAP12 NUAK1 FAM83H CDKN1A TUFT1 CNOT6 SERHL2 ZNF189 EP400 FGFR1 ASB7 FOXO1 CELSR1 DSP TMEM184A ARHGEF5 FAM83G GIPC1 SLC7A5 ZNF217 EPPK1 ITPR3 LAMA5 IFNE FZD1 WNT4 PRICKLE1 FEZF2 WNT2B FZD8 NFIC ATF3 JAG1 HERC2 MAFK NOTCH2 DHX34 NBEAL2 AP5B1 CSNK1D BRPF3 SCAF1 RAB43 SETD1B MIDN COLEC12 INSL6 CAMK4 IL18BP FABP3 SYT12 CD274 PREP HAS3 SOCS3 KCTD19 SIGLEC8 ETS1 KLF4 TNS1 IGFBP4 JUNB JUN ADAMTS15 ITPRIPL2 ERRFI1 WNK1 FASN MYO18A MEGF8 AGO4 IFNL1 SLC22A14 NSG1 CR1 FLRT1 CHRM5 SERPINA10 TNFAIP3 TMEM150C FUS INSR FOXK1 BCORL1 CLN8 SKI LIF BHLHE40 NFKBIZ SERTAD2 PFKFB3 SEC24B ARHGEF18 TLDC2 KLF7 LENG8 GPR75 COL7A1 HNRNPA0 MAP1B ZNF618 KDM3B MAML1 CEMIP DENND5A IL1R1 LRRN4CL SMAD9 SIK1 ABL2 TATDN2 POLR3H KCNJ11 SOCS7 ZCCHC2 ETV6 MARS2 TRIM56 ALG9 NEU3 GPRASP1 SPDYE1 ISL2 IFNL2 DDHD2 SMG1 LONRF2 RNF166 AHNAK2 ADAT1 NPR2 NPIPA1 PILRB ZNF573 ASH1L IGF1R SRRM2 ETS2 TICAM1 RBMS2 CERK AMPD2 DYSF ROCK1 CDON NBPF10 RIMBP3 PPTC7 PRKAG2 PTPRE SESN2 TRIB1 SERPINB8 MBLAC2 SEMA7A ADAM19 CSMD2 TBX18 ITGA9 HSFX1 GNA12 DHX36 RUBCN MTR AGO2 SPEN SPRY1 ATP2A2 PPP4C SEC16A TRIM11 SMURF1 MTRNR2L6 RDH16 DCUN1D2 DYNAP AKIRIN2 HEPHL1 C5AR2 ZNF324 TSPAN14 ZNF587 DCAF4 FLCN HELZ ZNF8 FILIP1 HMGXB3 KLHL21 JRK KCNC4 WDR81 TEP1 PLK3 CHST3 PODXL AKAP13 MLXIP ASB1 CRTC1 RGL4 SSH2 ELK3 SSH1 SLC9A1 NES HIPK2 SPG7 ZFHX3 UBE2Q1 MTHFR PLXNA1 KCNH8 KMT2A ADGRF2 KMT2C ZBTB18 RALGAPA2 WNK2 HECTD4 FERMT1 CBL ABCC10 PDGFB SETD5 CCNG2 CTCFL CHD2 NPIPB4 ABCA3 WDFY3 DCAF1 ADAMTSL4 RORC HK2 ZNF202 BCL2L2-PABPN1 PCYT1B UBR3 HUWE1 CRAMP1 GBF1 SULT2A1 MAP3K2 EYA3 MTF1 GEMIN4 GATA6 MAP3K9 ZNF746 MAP3K10 SUSD6 IREB2 ZNF142 FLNB OSBP CELSR3 PCNX2 KLHL18 ZNF764 TANC2 ZC3H10 MTMR9 MGA TIAM2 MTMR3 RASAL2 ZBTB24 BICD2 MED13L ZNF526 ZFX CEACAM19 ANKHD1 C18ORF25 DLC1 UHRF1BP1 SLC25A37 HIVEP1 MICAL2 CDRT1 LGALSL LTBP2 TLL2 MYSM1 DIP2B ANKRD50 PINLYP SBF2 RASGRF2 CAPRIN2 INTS5 PDE3A ZNF672 INTS1 GFOD1 DIDO1 KIAA0232 KIAA1549 ZNF275 BTBD7 PDLIM4 EIF3CL ZNF592 DNHD1 TRIO DNMBP HPS6 UBE2O HSPG2 CACNG8 NCKAP5L MFSD4B MORC2 ZBTB7A SPACA6 ZNF248 MCM3AP PIAS2 PADI1 PALLD OTUD4 DOCK5 RAPGEF6 RECQL5 RAI1 AHDC1 ZNF594 SNX33 GPR161 CAPN15 IRGQ GJC1 ZNF805 MED12L ONECUT3 DOHH KLHL36 DOCK7 KMT2D FBXL20 LMLN TTLL4 PRR14L USP20 ZKSCAN2 GTF2H4 ZNF587B ZNF562 PHKA1 GBA2 ZNF264 PPM1L FUBP3 ATP11A NDST2 SNTB1 POMK SUPT6H CELF1 JOSD1 ZHX3 ZSWIM3 LRCH1 POLR2J2 ZNF112 MPRIP CHD3 ZC3H13 CUL9 USP35 SLC12A4 TRIM66 ZNF445 ANKS1A KCTD13 GABPB2 CD3EAP ZNF496 NBPF19 BSN CARNS1 MAP6D1 TSSK3 FBXO41 SAG ST20-MTHFS SPDYE2B UBE3B NRDE2 TRRAP LRRC37A3 RNF169 SMIM11A POC1B-GALNT4 NPIPB11 HSPE1-MOB4 NPIPB5 CTRL AL354822.1 CTAGE4 CDRT4 NUDT13 BIVM-ERCC5 WDR27 RTEL1-TNFRSF6B NNAT YJEFN3 RNF103-CHMP3 ZNF670-ZNF695 POLR2J3 SULT1A4 GTF2H2C ADGB TMC7 ZNF586 LY75-CD302 FAM47E-STBD1 FAAP100 BORCS7-ASMT ASB18 GDPGP1 LBX2 ZFP64 NPFFR1 ZNF69 PHKG1 TBC1D3K FAM155A NTN3 NT5M ZNF816-ZNF321P ANKRD30BL ANKRD61 SCART1 ZNF18 NRIP2 INO80B-WBP1 ZNF440 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 4h from GSE148729 mock v SARS-CoV-2 Calu-3 4h totalRNA GSE148729 down UBB TIMM8B TBCA FCGRT SUMO2 UBD SPINK1 ETFA NPC2 UBE2D3 ACE2 ANXA3 IFITM1 ATP6AP2 RBX1 ZCRB1 KHK HLA-B GNG5 UBE2D1 TUBA1A ALG5 RAB18 PSMD4 OAS1 HLA-DRB1 ARL6IP6 TUBA4A SDF2 AGT SAP18 TSPAN8 NDUFB9 SRP72 HSBP1 ITM2A PHB NEDD8 HHLA2 MAT2B ISG15 RAB10 ARL14 MX1 TMBIM4 MDH1 CREBL2 LRRC40 LYPLA1 MRPL9 VAMP8 TPMT CLDN10 NDUFB6 ENY2 PSMA2 ATP6V1G1 RPS20 BTF3 OCIAD2 SERPING1 RPL37A RPS26 RPL35A CDK2AP1 TNFSF10 UQCR10 ARL3 RPL41 RPL37 GPX2 TSPAN6 FDCSP DEPTOR MT1E RPL30 PTGFR COX6A1 RPL24 RPS25 TSTD1 SLPI COX7C AGR2 VTCN1 CD24 MPZL2 STMN1 CYBA HLA-E TMED9 TIMP1 NDUFB5 AURKB POMP SPR CDK5 MT1F FAM72D AP2S1 RAB13 ATP6V1F SDHD RNASE1 AURKA CDK1 RPL26L1 SNX3 CCNB1 IFI27L2 DYNLL1 PRDX3 LIPA LGR6 AKR1C3 TCN1 PLCXD3 CKS1B MANF APLP2 CYCS KRT14 TMSB4X TMEM60 NUCB2 CD63 PSMA3 SAA1 UBE2T CFB PPM1N ARHGDIB MAD2L1 HMGB2 CENPE NEIL3 CTSS RAD51AP1 DNPH1 PSMB8 KIF18A IFI35 PPA1 EPHX1 PSME2 RPS28 UQCRB TSPAN13 YBX1 TMA7 COX17 CAPZB MYL12A TXN SYF2 GSTP1 ANAPC13 RHEB PSMB9 RPS23 CA2 SH3BGRL COX7A2L EIF3E MDH2 HLA-DQB1 LYZ SNRPD2 RPS21 CTSH EIF3K NDUFA13 PSMB6 PSMC2 PRDX5 VPS28 DNAJC8 DRAP1 RAP1B PFDN6 LAPTM4A NUPR1 ABRACL EID1 RPL18 CD74 RPL35 SRP14 PCNP OAZ1 NDUFA5 NDUFB7 NDUFA2 SOD1 ROMO1 TRMT112 PSAP MPC2 SMIM22 COX6B1 PSMA6 RPL36AL NDUFA6 ANXA1 HLA-DMA NDUFA4 SRSF3 SAT1 NOP10 POLR2K SUB1 VBP1 NUDT16L1 NDUFC2 DBI SEC61G CD164 PGRMC1 HIGD2A MIEN1 CACYBP BNIP3L DEK CBX3 TMEM14B DPY30 NDUFS2 ATRAID MAGT1 SNRPG PRR13 PDZK1IP1 TM4SF4 HAT1 CHMP5 S100A11 NDUFAB1 MRPL27 CRYZ ARL6IP5 PFDN2 SARNP PTTG1 TMX1 C12ORF57 YPEL5 UBE2N SMIM20 LAMTOR5 PSMB3 SRP9 TFPT MAGOH AMZ2 PSMD10 ZMAT2 TPRKB UQCRQ PIH1D1 PCNA BCAS2 WDR54 NDUFA12 COMMD8 SSB APEX1 STEAP1 PDCD10 POP5 NAA50 PSMA7 UQCRH AP3S1 HMGN3 GMNN DCTN6 MMADHC AKR1B1 SEC11C ITGB3BP C18ORF32 MRPL1 UBA3 TMSB10 HSPE1 SNRPE CUEDC2 SF3B5 TOMM5 RPL34 IER3IP1 MRPL18 PCSK5 GPBP1 TXNDC12 TMEM47 ARL6IP1 MNS1 AKR1B10 MSMO1 ZMPSTE24 MRPL47 RPA3 SLIRP JSRP1 BID RIPK2 POU2AF1 MUC20 C3ORF33 FAM111B DIRAS3 CCDC152 SEC62 TFPI2 MRPS11 SCOC CT83 LRRC31 PKIB RBM34 CX3CL1 PRSS3 NICN1 CSTB NAPA MDK RPL23A SERF2 MSRB1 COX5B UQCR11 SERP1 RPL36A THAP2 ONECUT1 HHLA1 SAA2 RARRES1 HOXB13 CCDC34 COPS4 TIMM23 VTA1 SNRPD3 SUPT4H1 PFDN4 PPA2 TIPRL PET100 RNF5 IDI1 C3ORF14 IKBKG ARL2 HPRT1 TMEM11 TXN2 NDUFB1 FKBP3 ARPC5 COX16 GPN3 SPP1 RNF181 APIP BOLA2B AURKAIP1 C19ORF53 COMMD1 CCDC115 COMMD6 C11ORF58 RPL17-C18ORF32 NDUFAF4 TSPAN1 PON2 CWC15 ITPA TRAPPC6A MCTS1 ST20 ANKRD22 HNRNPC CYSTM1 UROD IFT43 PUDP SPCS3 MMP7 SLC1A6 RLN2 CDKN2A MPHOSPH6 SLC44A4 FXYD3 DTYMK IFT57 MROH7 EIF4EBP1 POLR2F MRPS22 MT-ATP8 SLCO1B3 MTHFS RANBP1 GCSH GSTT2B GJB1 SULT1A3 RIDA CCNG1 PIN1 ZCCHC10 RWDD1 CDK7 CCNC TMEM59 RNASEK TMEM14C COX7B NDUFS5 AS3MT TIMM17A KRT23 TIMMDC1 CHRNA5 SSBP1 COMMD4 LAGE3 PLEKHB1 POLR3K FEZ1 MRPS21 LANCL1 RSL24D1 TCEA1 CCDC82 NAA38 ECH1 ZNF75A NSA2 LSM5 TMED7 LSM3 ZCCHC17 BEX3 CBY1 ALG1L TMCO1 WBP1 SVIP DERL2 FRG1 METTL5 PDCD5 PPP1R2 HIRIP3 ZNF85 ERGIC2 COA6 DUSP23 C1GALT1C1 BCAP29 MED4 BLOC1S5 FANCL AK6 CRIPT HIGD1A TBPL1 MZT1 TMEM38B LRRCC1 IQCK PLPP5 SPA17 ECHDC1 CENPQ EIF3M CFAP36 ZFPL1 BTBD19 NPHP3-ACAD11 HOXA11 DLGAP3 CECR2 SURF1 GTF2H2C_2 SMIM11B CTAGE8 ZNF625-ZNF20 PRRG2 SMN2 C1QTNF3-AMACR C9ORF135 SHANK1 RPS10-NUDT3 SLC35F4 SPIN2B 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells at 24h from GSE148729 mock v SARS-CoV-2 Calu-3 24h totalRNA GSE148729 up NKX3-1 F2RL1 RSRC2 SEC16B BIRC3 IL6 GDF15 CCL5 EGR1 UBD NMI TNF DDX58 IL1A CXCL10 IFITM3 CYP2J2 IFITM1 HLA-B NEDD9 LAP3 ZNF274 JAK2 KLF6 NPTX1 IFNL3 BRD2 RBCK1 SNIP1 OAS1 PTX3 HLA-DRB1 HLA-C STAT1 HLA-A IFITM2 SRPK2 B2M MYCBP2 HERPUD1 APOBEC3G OASL TRIM31 MOV10 CXCL2 IFNB1 ISG15 ZNF503 NUB1 CXCL9 ARL14 STC2 MX1 MYD88 WFDC5 OVOL1 ZC3H12C NR3C1 LIFR SIAE CD55 PCLO MT2A SLC16A9 TNFSF10 IFI27 DUSP16 EXT1 ZEB2 MTRNR2L8 PNRC1 CFH MTRNR2L1 SERPINB2 HSPB8 TET2 ANKRD33B SEMA3A ISG20 GCNT4 ZBTB20 ZNF462 CMTR1 UNC93B1 TNFAIP2 PTGER4 KSR1 PARP10 HBEGF APOL1 TYMP BST2 SLC15A3 ITGAM APOL2 HLA-E LMO2 AREG IFI44 SLC1A3 EPSTI1 SPRY2 C2 GRB10 BATF2 RASGEF1B CXCL8 IL7R G0S2 PTGS2 NCALD B4GALT5 BMP2 ZFP36L2 GADD45B SNPH PLAUR FOXO1 WIF1 NAV2 ATF3 FZD4 CEBPB SLC12A7 HELZ2 NUAK2 OGFR RSAD2 OAS3 IDO1 IL10RA IRF7 CFB ZBP1 NLRC5 GBP5 TNFRSF9 TAP1 CCL20 IFIT1 SECTM1 CTSS RYR2 CYP1A1 IFIT3 RTP4 HLA-F OAS2 C3 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 CCR1 GBP4 DHX58 C1R KYNU USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 MLKL CPXM1 LGMN STAT2 PML PLEKHA4 SOCS3 NFKBIE ADAR NT5C3A PARP9 PARP12 ARC SAMD9L GCH1 HSH2D ADM FAP IL4I1 INHBA RNF213 IFI35 PARP14 FOSL1 SOCS1 TRAFD1 SAMHD1 UBE2L6 ANGPTL4 TLR3 UBA7 FST SP110 CSF3 ACKR4 ZNF704 SCN3A EHD4 PSME2 KLF4 ZFP36 IER2 LY6E FOS IGFBP4 IRF1 PSMB10 RASGRP3 DUSP1 TXNIP ICAM1 DTX3L NFKBIA IRF9 PSMB9 GBP3 JUN IFI44L SERPINB9 TAPBP JUND ARRDC3 CD74 IFI30 CCNL1 THEMIS2 SAT1 FSCN1 KDM6B CREB5 ZC3H12A DDIT3 DUSP8 TRAF1 EGR2 IFNL1 PPP1R15A CSF1 TRIM22 JAKMIP3 TNFAIP3 HDAC9 PLA2G4C GIMAP2 GPX3 BBC3 NEURL3 LIF DUSP5 IER5 TIPARP CSRNP1 CHAC1 MAFF NFKBIZ TSC22D2 ZNFX1 FOSB PNPT1 MXD1 RPS6KC1 DNAJB4 DUSP10 TLDC2 TNFSF15 PRR15 ITPKC HIVEP2 C15ORF48 RND1 C3ORF52 NEDD1 CHSY3 REL ABL2 TAP2 CIITA ASNS SLFN5 CASP1 PPM1K IL15RA ZCCHC2 GCA CD40 TRIM21 TAPBPL TRIM56 ZC3HAV1 TRIM5 TDRD7 TRIM14 TRIM69 MAP3K8 RIPK2 IL15 ACTN2 IKZF3 TMEM229B IRAK2 HSCB PDGFRL PRKD2 HLA-DMB CXCL11 IFI6 GSDMB STX19 IL32 PER1 IFNL2 LAMP3 DDX60 SLC25A28 RNF19B LGALS9 TNFSF13B XRN1 SP100 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 ADRB2 SAMD9 GBP1 SPAG9 MB21D2 CD83 HES4 ETS2 CEACAM1 HDX RELB RCAN1 ETV7 BTN3A3 GMPR CPEB2 NFE2L3 PMAIP1 CX3CL1 HLA-DRA PATL1 NAPA ERAP2 SP140L ACHE APOL3 N4BP1 TMEM62 BTN3A1 C1S MOB3C HLA-DPA1 TRIM38 FAS FUT4 BLZF1 BTN3A2 IL12A PHACTR4 PIK3AP1 OPTN CFLAR RNF149 TRIM26 GLCCI1 PIK3R3 HRH1 KIAA0040 BACH2 SEMA7A KCNN1 NR4A1 IGF2 SAA2 CD68 NCOA7 ETV3 C4B MMD2 ANGPT2 IFNA7 C4A DICER1 TNFRSF1B PELI1 NFKB2 STK10 OTUD1 CYLD SMURF1 MTRNR2L6 AP5Z1 CITED2 AVPI1 EPHA4 GPCPD1 ERAP1 TEP1 SYNE1 MDGA1 PLK3 PODXL FA2H DAPP1 EPC1 SNAI1 PLXNA2 HLA-DOB PDGFA HLA-DRB3 TNFRSF10A RAET1L LRP2 ZBED5 DUOX1 KDM6A KMT2C COL11A2 DAB2IP HIP1R ZNF620 TTC26 ZBTB21 CHD2 ARHGEF38 TNFRSF10B AMBRA1 NOD1 RAB24 ZNF627 BTN2A2 GTPBP1 LPA SYNPO COL16A1 CELSR3 DCP1A FNDC3A PDZD2 BAHCC1 UHRF1BP1 LRRN3 ZNF385C FAM83A AFAP1 ENDOD1 UBN2 ZNF697 DNAH17 CNP FRS2 OPHN1 EIF3CL BAZ2B NOCT CPEB3 ARID4B PPP4R4 MED12L CFAP54 CPEB4 ARAP2 SIPA1L2 MFSD14A TTC28 PATL2 CFAP57 SEMA3D RUFY4 TRPC4 MAFA RANBP3L ZNF200 ST3GAL2 SYDE1 KCNV1 TULP2 PLCH1 SHROOM2 RGPD5 CXORF49 TTC9B CXXC4 CSAG3 CXORF49B ANKRD30BL STUM ZNF354B ZFP91-CNTF 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells at 24h from GSE148729 mock v SARS-CoV-2 Calu-3 24h totalRNA GSE148729 down MYH9 IFNAR1 EEF1A1 ERMP1 MAPK3 NIN CAPN5 NUDT2 SPINK1 CAPN2 ITGB1 KPNA2 MME RBL2 CACNA1D ATP6AP2 SCCPDH SLC30A9 ANXA2 VILL CENPF PMEPA1 GGT1 USP13 AP2M1 CIT TUBA1A PLS1 CTSD TSPAN8 USH1C LGALS4 ITM2A HS2ST1 PRKAR2A CAT GGH TOP2B MDH1 GLO1 CREBL2 MTFR1 SLC25A40 CLDN10 SCP2 UFC1 PTTG1IP NDUFV1 NDUFB6 IFT122 CAV1 RNF128 LCP1 NBEA VEPH1 SDC1 AK4 NT5DC2 ENAH PERP CFTR REPS2 BMPR1B SLC40A1 UPK1B SH3BGRL2 TSPAN6 METTL7B TRIM2 MARCKS BCAS1 RPS25 SLC16A7 EXPH5 SORBS2 CHST9 COPS9 NFIA EMP2 SLC25A23 VTCN1 CD24 TAGLN2 ATP1A1 TMBIM6 STMN1 GPR107 GSN TGFBI PIGK ITGB5 CMTM6 ABHD2 PLK1 DHCR24 TOP2A CCNA2 LMNB1 CCNB2 PLBD1 C5 CDKN3 HSD17B4 NEK2 DEPDC1B HMMR SPAG5 ALCAM ANXA5 ARPIN BUB1B KIF14 KNSTRN ASPM AURKA FADS1 BIRC5 KIF4A COMMD9 SAPCD2 KIF15 FAM72C PRR11 HDLBP TPX2 CCNB1 CEP55 IDH1 CDCA3 KIF23 PAPSS1 MKI67 LDHA SORT1 ALDH4A1 KIF20A SCD NCAPG PDGFD CRIP2 MLF1 AKR1C3 PTPRS TCN1 PBXIP1 TRAM1 ABCC4 APLP2 ABCD3 CYP24A1 PLCD1 LAD1 ANXA8 ANXA8L1 HACD2 SPDEF RAB4A ODAM PRC1 PTPRU TRIOBP CCDC85C ARHGAP11A CDC25C E2F8 CENPA CYFIP2 IQGAP3 NCAPD2 NUSAP1 PBK CENPI ARHGDIB RACGAP1 DEPDC1 CENPE DNPH1 SNCA DHFR CCDC18 SERPINA3 SLC3A1 DPYSL2 LASP1 YBX1 TMA7 PPP1CB COX17 THRA CAPZB RPLP0 CYB5A GNG10 LYZ CTSH ACAT2 MYH10 PRDX5 SLC12A2 MORF4L1 CETN2 EID1 VIM HADH MPC2 MXD4 GPI MYLK AGO1 GM2A EEF1G VPS35 NUCKS1 DBI PGRMC1 BNIP3L FAM102B OLFM4 PAH DMBX1 PFKFB3 ANP32A ERI3 ATRAID PDZK1IP1 TM4SF4 HMGB3 MRPL24 CRYZ ARL6IP5 POLD2 PTTG1 HMGB1 PARK7 LAMTOR5 SRP9 GPR160 ANP32E HAVCR1 RCN2 LMAN1 GNG12 PAM HTATSF1 FAM107B SLC39A10 UQCRH CXXC5 DHX40 HMGN3 MMGT1 ETFB VAV3 SERINC5 ARL6IP1 TMEM170B MNS1 TBL1XR1 PIK3C2B AKR1B10 SRI INSIG1 MSMO1 HMGCR SQLE CD46 CDCA7 ITGAV MCM6 PCYOX1L MVD ANKRD9 MKKS TNNT1 TCTEX1D2 TFRC FGFR3 LBR PCSK9 SFXN3 SYT16 CFI VPS41 MBNL3 SUMF1 FAM149A ACP6 SLC26A2 IDH2 SEMA3E GALNT12 AHNAK2 NEB TRHDE TMEM237 MLEC CBX5 KIAA0100 TTC3 APPL1 PCYOX1 DNAJC22 PRKACB VAT1 RALBP1 NOSTRIN HOGA1 GALM BRI3BP TM7SF2 CERK CMTM4 CHP1 BLVRB PDXK SARAF ST6GAL1 LMCD1 DNM1 ITGB6 ROR1 DPYSL3 KLK6 RARRES1 CCDC34 PRDX2 PGK1 IRAK1 PET100 COX11 RNF5 IDI1 UGT2B7 EGLN1 ROS1 CA12 SC5D GNPNAT1 TSN USP5 COPG2 FARSB SEPHS1 ARPC5 EEF1A2 COX16 SPP1 GALNT1 NNT TPM1 ALDH3A2 ASAH1 AHNAK ACAA2 ANXA4 CHMP3 COA3 GGCT NDE1 LRRC20 DYNC2H1 MSH6 HLTF OBSL1 TRAPPC6A MAZ ATP9A LSS KLHDC7A KLC4 MSI2 G6PD RTN3 MAP4 FARP1 UROD FDPS FDFT1 SMARCA2 SPOCK2 SREBF2 UGT1A10 CMBL TEX15 ACACA SLC44A4 HOMER2 PTPRF PROM1 SRD5A3 DTYMK TRIQK MBOAT2 NOTCH3 MYO1C TLR5 PRKDC LEPR SESN3 NCAM1 CYP51A1 ICMT SERPINA4 HGD GJB1 LMO4 CCNG1 XRCC5 GNPAT TMEM59 HNMT ACSF2 NYNRIN CTDSPL PALMD ANXA9 TMEM19 VANGL1 IKBIP NAALADL2 DARS2 ALDH7A1 HACD3 IARS2 GPC4 TNIK AIF1L CAPS KIF12 DHCR7 KCNMB4 NSDHL SAMD1 PMVK MMAB DSEL PLEKHB1 MAOB GALNT10 EBP TSPAN12 PGAP3 STRBP PFKFB2 DSC3 PXMP4 TBC1D5 CPD GPSM2 CD109 GPD1L HGSNAT IDS BICC1 STX10 SPNS2 ECH1 DCAF11 MYOM1 GOLIM4 FAM20B LSM3 NUDT3 MGAM2 ARSD SVIP NIPAL3 SGO2 SSPN CBX6 PPP2R3A ANKS6 CACNG4 IFT80 FAM168A TTC39C ERLIN2 CD99L2 ODF2 PALM3 NCMAP PAIP2B PDE1C OXCT1 MBTPS1 HNRNPR MGST2 ESYT1 PHKB UBXN2B G2E3 CXADR SMARCC1 AC012314.5 AC012314.3 AC012314.4 AC012314.6 CFAP73 HIP1 FAM172A 500 genes up-regulated by SARS-CoV-2 in human hiPSC-CMs cells at 24h from GSE150392 mock v SARS-CoV-2 24h hiPSC-CMs GSE150392 up F2RL1 PTPN14 IL1B RSRC2 BIRC3 IL6 GDF15 CD14 CCL2 MVP MALL SQSTM1 LOX THY1 IL1A ANKS4B TLR4 NPC1L1 MYRFL NDRG1 NEDD9 RUNX1 CD200R1 TLE3 BRD2 SERPINE1 SNIP1 OAS1 PTX3 PLOD2 TLE1 AGTR1 SLC30A7 PCK1 PLAT ITGA4 CXCL2 STOM IFNB1 FERMT3 STC2 MX1 MYD88 CHD1 MGAT1 MYO10 CXCL1 ITGA2 KLF5 INSYN2B TM4SF1 BMPR1B HES1 IL33 NT5E HLF NR4A2 SH3RF1 ELF3 OSMR CCDC80 FNIP2 SLC2A1 ANKRD33B SIX4 ISG20 TPST1 ATP10A ADCY7 PARP10 TRPV2 RPS6KA1 TGFBI DOK2 SLC16A3 ADGRE5 ITGA5 HLA-E NCLN MRC1 LMO2 C3AR1 LPL IFI44 STARD13 UAP1L1 CARD6 CDKN2B SLC43A3 CXCL8 ARL4C PTGS2 SLC1A7 CRY1 NUAK1 LINS1 SLC2A9 MYC KLF10 SLC2A3 SLC2A5 TRAM2 GADD45B PLAUR SPINT1 OSM JMJD6 GPR87 GTF2IRD1 RARG FAM83G SLC7A5 HR SOX17 FOXL1 ATF3 IRF8 TPBG BCL3 HELZ2 NUAK2 SBNO2 OAS3 IRF7 CFB GNG2 SELPLG TAP1 GPR176 SELE IFIT3 OAS2 CXCL3 APOL6 CMPK2 CDH16 PTAFR SUCNR1 MLKL SOCS3 ARSI NAMPT PTGES PIM1 CASP4 FAP LIPG INHBA FOSL1 HAS2 SAMHD1 HAS1 GFPT2 ARNTL ANGPTL4 DBP THBD KLF4 TOX2 FOS BMP6 IRF1 SGK1 DUSP1 ICAM1 DTX3L NFKBIA JUNB RAPGEF2 GBP3 JUN DRAM1 IFI44L ARRDC3 PIM3 ERRFI1 CCNL1 PHLDA1 GEM ADAM32 ZC3H12A LTA SLC25A25 AOC3 TRAF1 EGR2 NR4A3 RGS4 HSPA6 ART4 PPP1R15A MYCT1 CSF1 TRIM22 KCNE4 PTGER2 TNFSF4 TNFAIP3 SPDYA CIART PLA2G4C TG STC1 TOR4A DUSP6 LIF IER5 CSRNP1 BHLHE40 MAFF NFKBIZ KANSL1 IL11 FOSB SH2B3 SPRED3 LMAN1 AMIGO2 LRP11 RB1CC1 RLF USPL1 INTS6 GPBP1 PTBP3 TAF4B GRB7 HOXA5 ARRDC2 CREBRF IP6K3 HIVEP2 KDSR RND1 VEGFC GABPB1 CDH6 CENPL TMEM200A IL1R1 ZBTB2 REL ABL2 ANXA10 SMOX TRIM14 PDK4 MAP3K8 IL27RA IRAK2 MEDAG PRKD2 CYP1B1 CASS4 PCSK9 PER1 SLC20A1 PLAGL1 GALNT12 NHS TFPI2 SP100 GORAB CKAP4 PAPSS2 EMP1 LINGO2 PPP1R10 LIMA1 CD83 AFF4 RELB MICB BAZ1A PMAIP1 DUSP4 SLC2A10 SP140L ACHE BTN3A1 PANX1 CHSY1 TRIM38 CA9 SRGN AMPD2 CSF2RB CD44 PDE7A NBPF10 MRGPRX2 HRH1 FJX1 BCAR3 CLK1 SERPINB8 CHKA PIGA PAPPA NR4A1 TMEM255B LOXL2 IL1RL1 DOK5 SPOCD1 NR1D1 GAL3ST1 CSMD2 SPRY4 NCF1 NCOA7 C1QTNF1 C7ORF61 NPTX2 CDC14A HS3ST3B1 PRKCD CCL7 TMED7-TICAM2 AGO2 RECK SPEN HFE TNFRSF1B POSTN CA12 NFATC2 NFKB2 TXNDC5 PDCD1LG2 ELL UVRAG BHLHE41 TGM3 BOC SLC12A8 FLCN EPHA2 RBBP6 SMIM3 PTP4A1 KCNJ6 SNAPC1 P4HA1 PLA2G4A CDCP1 GREM1 SGK2 HAPLN3 PLK3 ENG TET3 MFSD12 BCL6 KCNH7 NFKBID RNMT SNAI1 SPRED1 SPHK1 APLN SRPX2 SLC5A3 ACVR1C PYY CPM CPA4 PER2 OVGP1 SLC22A3 ZPLD1 PCDH15 JMJD1C SSTR1 ASXL1 ZBTB21 CHD2 TMEM119 KCNAB1 TNFRSF10B EVA1A PRR5L CRTC2 FPR3 TFPI SLC19A2 CXCR1 PPM1D IL13RA1 ULBP2 CTH PTBP1 TBC1D15 ZBTB17 BAAT C9 RFX3 TNC GPAT3 UGCG SHMT2 ERO1A LOXL3 UBASH3B TMEM87B PFKFB4 KCTD5 AEN PDZD2 ZSWIM4 SKIL ARHGEF28 L1CAM CLK4 HIVEP1 NBPF14 FAM43A SLC9A7 NABP1 RASGRF2 IFRD1 CLMP CACTIN SERTAD4 PDE10A BICC1 AGAP6 RAB27B PCF11 FOXN2 LRP5L H2BC8 H2BC18 ARID4B NBPF26 GRIP2 ATL3 EMILIN1 CEP95 SNX16 ZNF143 PPP4R2 GOLGA7B LAYN GALNT15 ADARB1 DAB2 SSUH2 ARHGAP26 PDP2 NR6A1 CHD7 CARS1 KCNG1 TTLL8 RFLNA AC025263.2 GPR180 FNDC11 NXPE2 AC073610.2 SMIM41 OOSP3 WNK4 BNIP5 NPIPB7 CSPP1 DCBLD1 PTGIS TMEM158 ACTBL2 POFUT2 AC015813.2 AC116366.2 AL049844.1 LSMEM1 PXT1 KRTAP5-2 TIGD3 SLC35E1 LDB2 INA NPIPB6 TNFAIP8L3 NRG3 CABP5 AC008770.4 ASPHD2 IPMK CFAP43 CFAP45 PTPRN NPIPB9 AL135905.2 NBPF19 TGIF2-RAB5IF SPOPL PTCHD4 TECTB ELOVL3 500 genes down-regulated by SARS-CoV-2 in human hiPSC-CMs cells at 24h from GSE150392 mock v SARS-CoV-2 24h hiPSC-CMs GSE150392 down GOT1 TRIM55 SH3BGR PRKACA ACE2 TMEM97 AGTR2 SCCPDH CENPF VIPR1 BZW2 BRCA1 PRKAR2B SLC5A12 EPHX2 CAT FRMD3 ACADS PDE4DIP UBE2E1 SCRN3 ADHFE1 NSMCE4A SRR NUDT12 ATPAF1 ALDH6A1 TMEM71 PPP1R14C NEBL SLC40A1 TTC39A STK33 UPK1B HOPX METTL7B NME5 CRYM PBX1 ITGA10 KLHDC9 SSBP2 SORBS2 KIAA1143 CHCHD10 EMC10 PLCB2 GPD1 CPVL PLK1 MYBL2 TOP2A ZWINT CDCA8 CCNA2 TK1 TROAP LMNB1 CCNB2 SMARCD3 PLBD1 GTSE1 CDKN3 NREP AURKB NEK2 SHCBP1 NUF2 CDCA5 ITGA7 KIF2C KNSTRN NUDT16 FH HADHB DLGAP5 RRM2 CDK1 CDC6 E2F1 BIRC5 KIFC1 ROGDI LGALS3 CCNB1 NCAPH CEP55 CDCA3 ACO2 CDC20 HJURP TRIP13 CENPU TTK CDC45 KIF20A DTL NCAPG TYMS CORO6 ENPP5 MTERF2 MLF1 G0S2 YPEL1 NAP1L2 BMP7 PLCXD3 SLC2A8 AQP10 FOXM1 NECTIN1 EPN3 CDH3 RHPN1 CLU FGF10 FRZB SFRP2 FGF12 ODAM TYRP1 SLC8A1 PRC1 GRID1 POPDC2 UBE2T ASF1B KIF22 GINS2 CKAP2L CHAF1B GATM FAM83D SPC24 OIP5 NUSAP1 CKAP2 MCM5 PBK SPC25 CENPM DEPDC1 FAM78A STAT4 HMGB2 NDC80 CENPE NEIL3 RAD51AP1 TNNT2 CASQ2 TRDN XIRP2 HSPB3 TNNI3 FABP3 ITGB1BP2 CSRP3 TXLNB NPPA PGAM2 MB CKMT2 MYL4 MYL7 POLE2 ALAS2 DHFR UNG TMEM143 CPNE5 HAND2 TNNI1 KCNIP4 ACTC1 COX6A2 TNNC1 MYL2 CLIC5 QDPR HADH FAM189A2 ACTA1 LIMS2 FAM107A MYLK GYG1 CD36 NUCKS1 FXYD1 MYZAP LDB3 FBXL22 ART3 SULT1E1 BMP5 EDNRA COL21A1 ASB2 C1ORF105 COL9A1 GPX3 ANP32A NDUFS2 HMGB3 ATP6V0E2 SLC29A1 FGF13 AKR1B1 DECR1 SRPK3 SORCS3 ZNF385B ZBED8 IFT88 HFM1 FEN1 APOBEC2 TSPAN32 GPR183 ADPRHL1 RXRG C14ORF180 TCAP CRACR2B FAM185A RGN TESC PLAC1 PTGR2 CLGN CRABP2 DRD1 APCDD1 FAM111B DIRAS3 LIG1 RHNO1 CDCA7L ZNF302 REC114 MEIS2 CLUAP1 UGT2B28 NICN1 GALM MYL9 ARMCX1 RASSF4 PDK1 DOK7 LMOD1 EGLN3 DAPK2 RCAN2 LSMEM2 SLC6A2 MLIP SLC30A3 SLC38A3 HRC CASQ1 HAND1 GJD2 CPNE4 ASPG CLCNKB CORIN KCNH2 CCDC34 MOG MASP1 GATB PEX3 RMDN1 PARP1 TRIM54 FARSB HAUS8 EEF1A2 ANKRD18A ACOT2 ACOT1 ATP5F1A CIRBP ACAT1 C11ORF71 ALDOC FILIP1 ANKEF1 SUSD2 PDE1A IFT81 DMPK PRIMA1 SFRP5 FLOT1 NES FXYD6 TDGF1 ATP6V1G2 TNNI3K SPOCK2 KCNIP2 SIRT3 HCN4 FAM13C CALN1 NRXN1 COL11A2 FERMT1 TMEM144 PCLAF RAB9B SCHIP1 FSD2 DHODH HRH2 CAMK2A RPE65 CPT2 ACSM5 SLC27A6 SENP8 MAP3K20 GUCY1A1 SGO1 PRMT6 CAV3 RGS6 RBM38 BABAM2 TMSB15A SETMAR LPAR3 MMP15 HSPB7 RCSD1 SELENOP TMOD1 ENO3 DTNA PDHA1 FMO4 HNMT PALMD BCKDHB RMI2 PXYLP1 SH3RF2 AIF1L CSPG5 MMAB TMEM141 MAOB PGAP3 FPGT VSNL1 EFCAB7 CCDC121 PPP1R3C MAN1C1 FRMD5 MANEA NHLRC3 ICA1 PDK2 FAM222A C19ORF47 RFC3 FOXRED1 TSEN2 KLHL23 A4GALT DMAC1 SLC26A9 PHYH TLCD4 FANCL LRRCC1 OXCT1 ACOX2 LDHD PCCB ACAD8 NUDT7 ISOC1 AMT STRIP2 CAP2 CAMK2B REXO5 WDR5B PLK4 SGCA TRH RASL12 SPEG DES RALGPS1 MTURN CLYBL SORBS1 TAF9B EXOG ALDH5A1 C1QL1 ZNF561 INAFM2 C15ORF41 ZNRF2 TMEM106C AC091551.1 ATP1A2 FAM47E NAP1L3 MTUS2 MSS51 ZNF418 PPP2R3B PPP1R1C SMCO1 SMPX EFNB3 TBX5 ULK4 FITM1 TECRL MYOCD GPR22 COQ7 DGLUCY SPSB4 LEFTY2 ANKRD63 KLHL3 MKS1 CNOT11 PMEL TBX20 SMTNL2 SUSD4 C11ORF21 GJA5 HEY2 COA5 HHATL PPP1R1A PDE6B GPR27 PHACTR1 TMEM163 SPX CCDC87 AC009133.6 INKA2 MARCHF11 MPPED2 HIF3A SHD HMGCLL1 VSTM2L SMYD1 MACROH2A2 PKIA COLQ TSNAXIP1 GABRA4 C17ORF97 SH3GL3 SYNPO2L AC008575.1 FPGT-TNNI3K PLPP7 SLC35D3 GNG7 NTF4 LMOD2 C11ORF52 PTGES3L LRRC10 CAPN3 FAM133A ZC4H2 PPP1R12B CRPPA RNF207 TNMD CES4A GSG1 IL20RA TMEM229A CAVIN4 SPEF2 AC108488.2 SNAP91 ENHO NIPSNAP3B TAFA2 500 genes up-regulated by SARS-CoV-2 in human Organoids cells from GSE154613 SARS-CoV-2 mock v DMSO Organoids GSE154613 up NKX3-1 IL1B BIRC3 IL6 CCL2 CCL5 MVP VCAM1 EGR1 UBD SPINK1 NMI TNF CXCL5 THY1 DDX58 CKM CXCL10 IFITM3 CYP2J2 IFITM1 REG3A HLA-B LAP3 IFNL3 SERPINE1 RBCK1 SPTBN5 OAS1 FCGR2A PTX3 DMBT1 STAT1 TRIM25 IFITM2 AGT B2M EIF2AK2 IL22RA1 TMEM173 MGAM APOBEC3G OASL SLC16A6 MOV10 CXCL2 STOM IFNB1 ISG15 NUB1 CXCL9 MUC13 MX1 MYD88 OVOL1 SERPING1 TMC5 MT2A CP CXCL1 CXCL6 TNFSF10 CFTR IFI27 NT5E GCNT3 DUOX2 ELF3 TNS4 CFH SERPINB2 RND3 KRT15 ISG20 SNHG16 ATP10A UNC93B1 TNFAIP2 AQP3 IL4R PARP10 LGALS3BP TOR1B APOL1 TYMP PROS1 BST2 B3GNT7 SLC15A3 APOL2 ITGA5 HLA-E FBXO6 SDC4 LMO2 TROAP IFI44 CDCA5 ORC1 EPSTI1 RGS16 C2 ABCD1 BATF2 TRIP13 LDHA DTL MAP3K6 EBF4 CHI3L1 A2M CCL4 GADD45G MMP1 GLYATL1 AXL STAT5A CISH EDN1 PLAUR KRT14 SEMA4B CDH3 WNT4 SOX9 FGF1 ATF3 IRF8 HPX BCL3 TNFRSF1A HELZ2 NUAK2 OGFR SBNO2 SAA1 RSAD2 CDC25C GRAP2 OAS3 IRF7 CFB MTFR2 SEPT1 NLRC5 IL18BP GBP5 TNFSF14 TAP1 CCL20 IFIT1 SECTM1 RAC2 CLEC7A GLIPR1 MASTL S100A9 IFIT3 RTP4 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 PSMB8 CD274 APOL6 GBP4 DHX58 C1R KYNU USP18 CMPK2 IFIT2 IFI16 PTAFR FGL1 HERC6 IFIH1 MLKL STAT2 PML PLEKHA4 FGG SOCS3 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L HSH2D CASP4 FAP RNF213 IFI35 PARP14 FOSL1 SOCS1 TRIM6 SAMHD1 PPA1 UBE2L6 TLR3 PLAU UBA7 WARS SP110 IRF2 EHD4 PSME2 KLF4 ZFP36 SHISA5 IER3 FOS IRF1 PSMB10 RASGRP3 TGM2 TXNIP ICAM1 DTX3L NFKBIA IRF9 JUNB PSMB9 GBP3 JUN DRAM1 LYZ IFI44L RNF114 TAPBP SDPR C10ORF10 IFI30 DNAJA1 THEMIS2 RBM11 KIFC3 SAMSN1 ZC3H12A MAB21L2 FGB TRAF1 IL16 IFNL1 AOX1 PPP1R15A CSF1 TRIM22 TNFAIP3 PLA2G4C MUC1 NEURL3 LIF CCRN4L DUSP5 IER5 CSRNP1 BHLHE40 MAFF NFKBIZ ZNFX1 CHMP5 SPRED3 PNPT1 SLCO2A1 MMP9 HABP2 RND1 CD47 ITPRIP ODF3B NNMT TAP2 CASP1 PPM1K IL15RA ETV6 CD40 NLGN2 TRIM21 RNF31 CREM TAPBPL FAM46A ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 TRIM69 DLL1 MAP3K8 IL15 AZI2 OLR1 IRAK2 PRKD2 CXCL11 VNN1 IFI6 GSDMB IFNL2 CFI LAMP3 DDX60 CEACAM7 SLC25A28 RNF19B C19ORF66 LGALS9 TNFSF13B SP100 RARRES3 BCL10 MX2 IFIT5 HERC5 TRANK1 C17ORF67 DDX60L TMEM140 SAMD9 GBP1 CASP7 PAPSS2 HES4 ETS2 CEACAM1 RELB RCAN1 ETV7 BTN3A3 GMPR PMAIP1 TICAM1 NUDCD1 STYK1 ERAP2 SP140L C5ORF56 RHBDF2 APOL3 N4BP1 WHAMM TMEM62 BTN3A1 C1S HCP5 SOD2 MOB3C VNN2 TRIM38 RABGAP1L PARP8 BTN3A2 IL12A IL7 IL18R1 PIK3AP1 OPTN CFLAR C8ORF4 GTPBP2 TRIM26 SERPINB1 CASP8 CD44 P2RY6 KIAA0040 DAPK2 LOC145837 AIM2 LAMP5 KRTAP2-3 C4ORF26 KRT6A PLSCR1 CARD11 HRASLS2 KLK6 SAA2 CD68 NCOA7 TACR1 VNN3 HAND1 FAM26E IFNGR1 CCL3 IKBKE CCL7 APOBEC3F TNIP1 PIK3CD CARD16 BCL2L14 CXCR4 XBP1 NFKB2 PDCD1LG2 SQRDL CYTH1 KCNJ15 C6ORF62 FGA MDGA1 NIPAL4 NME8 DAPP1 GBP1P1 JAK3 S1PR2 LRRC32 ITGA3 NPHS1 NFAM1 DNPEP ECE1 NPAS2 KCNJ5 GLYATL2 KRT34 PTP4A3 PLEKHG7 CLMN LRSAM1 EVA1A FLT3LG EXOC3L4 PTGIR MTHFD1L GTPBP1 SERPINA11 TDO2 AEBP1 LAPTM4B PODN CASP10 STARD5 HSD3B7 KRT23 C6ORF222 APOBEC3D GMPPB THSD1 S100A7 SPRR2A GNA15 EPGN CNP SAMD11 CDK18 C2CD4A TEAD4 CACNG8 TGIF2 VWA5A C1RL GGACT NT5C3 RELL1 KCNK1 DNAJC12 NRG3 TMEM163 ATHL1 IL8 LOC100507463 SLC18B1 C2CD4B GRM4 ASCL1 SH3RF3 ZNF101 ALPK2 UNQ6494 PTOV1-AS1 KIAA1199 KCNC2 RAB3C LOC339535 LOC389791 LOC388692 SMTNL1 FTSJD2 S100A7A C20ORF118 RAB19 CHRNA3 CHRNA1 RGS20 HMSD LYPD5 CCBP2 LOC100506190 500 genes down-regulated by SARS-CoV-2 in human Organoids cells from GSE154613 SARS-CoV-2 mock v DMSO Organoids GSE154613 down LCT DPP4 GLYCTK SLC17A4 STX3 AADAC SLC1A1 CDH17 TOM1L2 CREB3L3 UGT2A3 ANKS4B MYO1A EPB41L1 ACE2 TMPRSS4 VIL1 TMEM97 FABP1 UNC93A PDZD3 SLC30A2 NDRG1 SLC7A9 HEPH PKLR ANXA13 ACE PCSK6 PLAT ITM2A MEP1A HHLA2 ITLN2 EPHX2 IGSF9 ADHFE1 SBK1 METTL7A RNF128 ENTPD3 RARB SLC15A2 SLC40A1 FGFR2 SH3BGRL2 SMPDL3A BCAS1 MAP6 SYTL5 SLX4IP GSTA1 SYBU GABRP ATP1A1 SLCO2B1 LDB1 GPD1 NREP RNASE1 MAFB ADAMTS2 MYO7A IDH1 KCNMA1 KY PER3 PZP TPPP FAM131B PTGDR2 YPEL1 SPON1 CDHR1 ABCC8 PLCXD3 ABCC2 APLP2 MMP11 CTNNA2 FAM20A WNT7B SLC9A2 HR RHOU RAB4A FRAT1 DKK1 FRZB ANKRD6 OCA2 OSBPL1A CASR PAX6 FMO9P COL6A6 ZNF862 KCNJ16 GATM SLC29A3 PPM1N CYP1A1 ALOX15 GPR113 SLC7A8 HEPACAM2 UPK2 CD177 STON1 LGI3 HMGCS2 KL PSAPL1 EPHX1 ATP13A4 CDH22 PIPOX LRRC17 LRAT VSTM2A AARD HPGD TSPAN7 CA2 VEGFA GLUL TSC22D3 CSF1R AQP1 UBE2V1 FASN ACADSB BNIP3L GEM ANK1 ARRDC4 PTGER3 ZNF132 LOC646903 ASXL3 SPOCK3 SERPINI1 LYPD6 PTGER2 GSTA2 ABCA4 COL21A1 DCC CDH18 ZFP14 STC1 CLN8 GPR157 GPR160 FAM107B CXXC5 MXI1 PCSK5 FAM117A BTD VAV3 HTR1D GNAZ TMEM139 HMGCR KLHL24 SALL1 BTBD11 LPPR5 STXBP1 NAALAD2 C2ORF72 PNPLA3 ITGA11 PDK4 CTSE CDC42BPG SLC6A4 F7 FGFR3 CASC1 PCSK9 DDX43 SEC14L5 DUSP9 SUMF1 BBS2 CCDC152 PDZK1 C3ORF80 CNNM3 TTC8 FAM179A PKHD1L1 NEFL PANK1 CERK RBBP8NL UGT2B15 SPTSSB GRIN3A FLRT2 LINC00643 CDH12 JARID2 UPB1 SSTR2 SSTR3 APBA1 PAMR1 LAMA3 TNFRSF10D CTNND2 ANO1 SLC38A3 PKD1L2 CHRNA2 CLDN19 ATP8A2 KCNK16 IL21R ANKRD34A KCNH2 RNF125 MTSS1 IDI1 UGT2B7 PCSK2 ARRB1 ZNF501 WDPCP SCD5 VSIG1 ALAD ALDH3A2 ASAH1 ALDH3B1 KRT1 EPHA4 MPHOSPH8 MSL3P1 RAP1GAP MAP3K3 MATN2 FAM102A SMPD3 DSCAML1 SFRP5 ATP7B KANK2 PDGFRB SH3YL1 PELI3 SLC14A2 SPOCK2 DGKG LIPC ACVR1C MTHFR GCK SLC26A3 PITX2 NKX6-1 ADCY1 ZG16 SEMA4G HCN4 SLC9A4 CMBL SLC30A8 G6PC2 KCNH6 PRSS12 SSTR1 AMOT OPRK1 ARHGAP6 TMEM119 TPBGL DAPK1 DDIT4L RAB26 BHMT UGT1A1 SCARA3 FFAR1 NCAM1 CTH ABCA2 ABTB1 CYP39A1 SULT2A1 TUBB1 AKR1C2 NAT1 OSBP2 SLC27A6 DIO1 ACSS2 DNMT3B RGS6 ALDH1A2 CCNG1 MMP17 PLCG2 ANXA9 FITM2 PEG10 ZC3H10 SH3RF2 FAM173B RERG MAOB B4GALNT2 KLHL4 PFKFB2 SLC44A5 CCDC121 ZBTB7C ANKMY1 CNTNAP3 SRGAP3 MCOLN3 NTN4 RAB39B C1QTNF6 CABLES2 MYRF C11ORF95 NCK2 FAM155B DIRAS2 ZNF516 TMEM38B PAIP2B CROT SH3BP5 PTPRN2 EZH1 FAN1 PLCL2 ST3GAL6 KIAA0513 WDR19 LGI1 TTC33 LMX1B MGAT3 LAMA1 IYD GOLGA2P5 CNNM1 ERP27 TSPAN2 DPCR1 PDP2 FOXE1 PLA2G10 ASIC1 RAB11FIP4 MTUS2 MSS51 C6ORF211 MIR4442 IQSEC2 LOC100131691 SYCP2 SC5DL LOC100132891 LOC100129550 HCN2 LOC100505817 CCDC176 PKD1P1 CARNS1 FMN2 FLJ22184 ZNF385D FAM154B NEFM SLC18A1 TCF24 LPPR1 MMRN1 SEZ6L MAP3K15 C21ORF88 GPR158 NPHP3-ACAD11 AMIGO1 ARX BEND6 GNAO1 RIMS4 HOXD8 GADL1 CCDC141 EDARADD AMY2B LPAR4 CNTNAP3B SRCIN1 IQSEC1 SGSM1 ZYG11A C1ORF158 MYLK3 DBT FRRS1L LRRIQ3 KCNK3 PRRT1 IGDCC3 CAB39L SLC35F4 GPR123 RHBDL1 LOC100270804 GRB14 AGBL5 LOC100133331 C7ORF13 C7ORF41 ADARB2 PFN4 FAM19A2 FBN3 METTL24 SH3GL2 AJAP1 AMHR2 KIAA1875 ZNF32-AS2 TMEM231 SCN4B LOC100128750 OGDHL CLDN9 LINC00261 LOC100506343 NXPH2 FBP2 HIATL2 FREM1 KCNH5 ZNF354A SCNN1G C17ORF103 AKD1 CPEB1 DBIL5P TBL1Y MFSD4 CASC2 RBM26-AS1 MST1P2 GAS2 SCRT1 ILDR2 ABP1 LINC00617 USP6 SLC8A3 SNED1 C5ORF4 CXCR7 C14ORF37 SYT17 LOC338758 PAK7 PACRG ATP6V1B1 SYT2 SEC22C TMTC4 PBX3 LOC285074 FAM21A LOC100505783 DNAJC28 FLJ46300 SLC9A5 PSG9 LOC100507547 SLC30A10 NOV ADAMTS18 LOC100505687 FAM63A HS3ST4 BZRAP1 CCDC154 CDKL1 RASGRF1 PXN-AS1 USP30 LOC283683 GPER LDLRAD1 ZNF333 500 genes up-regulated by SARS-CoV-2 in human A549 cells from GSE154613 SARS-CoV-2 mock v DMSO ACE2-A549 GSE154613 up NKX3-1 RPS27A IFNAR1 IL1B RSRC2 BIRC3 IL6 GDF15 HSPA5 CCL2 EGR1 UBD CXCL5 IL1A LYN RUNX1 JAK2 KLF6 SLC46A3 SMAD3 NCK1 NFKB1 RAB18 BZW2 ATP1B1 PLOD2 ST3GAL4 ADAM17 STAT1 TRIM25 PDE4D TLE1 B2M SDE2 SLC30A7 TDP2 TRIM31 CXCL2 STOM TMED5 ZNF503 HKDC1 EDEM1 UBE2E1 ZC3H12C VLDLR TFAM CD55 TRIM37 ACO1 CHMP2B BCL2A1 MCL1 RASEF TMC5 CP CXCL1 ITGA2 ASS1 CEBPD KLF5 RGS2 DUSP16 ZEB2 NR4A2 RAI14 CA8 OSMR KIAA1217 PNRC1 SOX2 RICTOR MARCKS STEAP4 EVA1C ANKRD33B PRDM1 SLPI FOXQ1 LCN2 ABCA1 EHF SNHG16 TC2N PLEKHS1 SLCO2B1 TNFAIP2 IL4R APOL1 TGFBI TYMP CPVL SDC4 CTSB CREG1 GLRX FRRS1 MAPK6 DDIT4 ELL2 ALCAM SLFN11 ARNTL2 NRIP1 G0S2 PTGS2 B4GALT1 SLC2A6 HINT3 KLF10 SLC2A3 MANF TGFBR1 STAT5A PLAUR RHOV LAMB3 WWC1 SP6 EREG ATF3 GABARAPL1 MAP2K3 HIF1A CTSC TPBG BCL3 FOSL2 CEBPB SLC12A7 NUAK2 SBNO2 SAA1 CFB TNFRSF9 TNFSF14 CCL20 GLIPR1 CTSS SELE LACC1 C3 CXCL3 APOL6 CYBB C1R KYNU IFI16 NAV3 PML FGG SOCS3 NFKBIE NAMPT TIFA GBP2 RHCG PARP9 SAMD9L GCH1 NFIL3 XDH PTGES SERPINA3 FOSL1 HAS2 GFPT2 UBE2L6 PLAU AHR FTH1 CLIC4 THBD SPTSSA ZFP36 TNS1 IER2 EPAS1 IER3 FOS IGFBP4 IRF1 SGK1 TGM2 ICAM1 DTX3L NFKBIA GBP3 JUN DRAM1 PLIN2 SERPINE2 SERPINB9 PTP4A2 RHOQ ARRDC3 PTGR1 C10ORF10 NDUFA5 PLEKHG2 CCNL1 FNDC3B NAB1 FSTL1 LXN PHLDA1 GNG11 PHLDB2 SAT1 NDUFV2 NRP1 GEM KDM6B MFHAS1 ZC3H12A DDIT3 SLC25A25 FGB NR4A3 PPP1R15A TRIML2 CSF1 B3GNT5 TNFAIP3 PPAP2B ZNF292 PLA2G4C CLSTN3 STC1 DUSP6 PPP1R15B LIF CCRN4L DUSP5 IRS2 IER5 TIPARP BHLHE40 MAFF NFKBIZ SERTAD2 FOSB SLAIN1 PDZK1IP1 UBLCP1 GOLT1B EMG1 GJA1 STEAP1 USO1 RB1CC1 SIRT1 RLF MORC4 CDC25B PTBP3 DNAJB9 NCOA4 RSPO3 DUSP10 ITIH2 ID1 EFNA1 C6ORF120 HDGF PRRX2 HIVEP2 C15ORF48 RPIA RND1 ROBO1 CD46 CD47 ITPRIP MKKS NNMT SLFN5 ETV6 BID CREM DCP2 RASD1 MAP3K8 RIPK2 AZI2 OLR1 IRAK2 PDGFRL CYP1B1 VNN1 C6ORF141 BMPER IL32 TMEM133 TFPI2 RNF19B GBP1 CCNT1 TOP1 GJB2 EIF5B PAPSS2 GFPT1 ANKRD12 RNF145 ZNF567 ESCO1 CD83 PLK2 HDX RELB RCAN1 BAZ1A PMAIP1 C1S SOD2 SLC19A3 OPTN CFLAR C8ORF4 RAB8B SRGN MMD RAB31 CD44 RASGRP1 HRH1 TRIB1 SERPINB8 BACH1 STK17A PAPPA NR4A1 COL12A1 PLSCR1 CRLF2 SPRY4 SAA2 NCOA7 C1QTNF1 SLCO5A1 RARRES1 IFNGR1 IFNAR2 IKBKE SFR1 RIT1 TNIP1 NPC1 XBP1 CA12 NFKB2 UXS1 UGP2 TOM1 LACTB SQRDL TMEM165 OTUD1 CYLD C6ORF62 PDP1 ZBTB10 SNAP25 CLDN1 VEZT SYCP2L DNAJB11 C4BPA PTP4A1 ACSL4 BTG3 PON2 SNAPC1 SOCS6 SLC39A8 MRPL33 PTPN12 PLA2G4A SMIM13 FGA GREM1 GABRA5 DLL4 ZHX2 TBC1D7 BCL6 LBP MAP3K13 CCDC71L NFKBID ABLIM3 KPNA4 ACOT9 ACBD3 AMPD3 NPHS1 NFE2L2 ZBED5 KDM3A STEAP2 KRAS TBC1D12 ZBTB21 CHD2 IL6ST ZFAS1 PROX1 MREG ZFAND5 TFPI PLD1 ZNF613 RBAK GDAP2 AKR1C2 CLINT1 TDO2 AKR1C1 SLC23A2 NAA15 UGCG ERN1 CASP10 SLC11A2 NFKBIB SDCBP OGFRL1 PNKD F11R MFSD1 WTAP FGD6 ABTB2 FNDC3A ZSWIM4 HIVEP1 FEZ1 LTBP2 MIER3 DENND4C CLDN12 NABP1 CEBPG TRIM36 TDG TRMT10C SOCS5 CDC42SE2 SLC26A9 TMEM2 MAK16 FOXN2 GOPC TMED7 SLC25A30 FRS3 ARID4B TLK2 CPEB4 PDCD5 COA6 C1RL SLC7A2 ETNK1 ZNF614 STRIP2 RASSF8 IRF2BP2 PPP4R2 DOCK4 DNAJC12 LARP4 ARHGAP42 SAV1 ERO1L SLMO2 RDH10 IPMK ZDHHC21 CTSL1 COPS2 SLC44A1 IL8 CSDA LOC643201 FBXO30 CNTNAP1 LPAR1 DNAH2 USP12 PION FAM210A RAB7L1 LOC645638 TMEM39A UNC5D DOM3Z LOC100289092 ZFYVE16 500 genes down-regulated by SARS-CoV-2 in human A549 cells from GSE154613 SARS-CoV-2 mock v DMSO ACE2-A549 GSE154613 down MYH9 DCAKD CEP250 PIGS NINL SEC14L1 MALL SPTAN1 ERGIC1 CDH17 TOM1L2 MACF1 ZZEF1 MYO1D EPB41L1 MYO15B ARRB2 EZR TYSND1 ANXA2 NF2 NDRG1 SLFNL1 CDHR5 COL4A3 AP2M1 CIT CLDN15 SERPINE1 FYCO1 ENPEP TCN2 DNMT1 TUBA4A NUTF2 COL4A4 EPS8L2 USH1C TLN2 EPHX2 FRMD3 TRAP1 PLEKHA7 FGFR4 ASB9 CAV1 RPS26 NEBL ZNF532 UPK1B COBL HIST1H2AG METTL7B PLCE1 GALNT5 C1ORF116 BCAS1 SLC2A1 MALAT1 AGR2 KCNQ1OT1 ZBTB20 SYBU UNC93B1 PYGB DDX41 THBS1 MICAL1 FLNA MYADM ITGB5 SPATA20 NDST1 SMAD7 ACLY PLK1 MYOF CLTCL1 DHCR24 NOL3 KIF18B IGFBP2 KIFC1 SPRY2 OLFML2A GRHPR MKI67 PTCH1 TPM2 YPEL1 NCALD CAMK2N1 PLCXD1 PLCXD3 COL1A1 TRAM2 ABCC2 AXL PLCD1 CGN AP1M2 MLPH TMC4 THEM6 TMEM184A JAG2 PLCD3 KRT80 TPD52L1 HR RHOU CLU SFRP4 HERC2 IPO9 MAP2K6 BMP1 SOX12 SORL1 IQCE NBEAL2 ZNF862 CYFIP2 FAM64A IQGAP3 PREX1 CRMP1 POLE PHF19 DPF1 KDM4D DCDC5 GLIPR2 BTBD16 CAV2 PFN1 LASP1 CYR61 CYTH3 THRA HPCAL1 CTGF S100A4 ADAMTS15 IL3RA AQP1 FAM134A MYLK LBH IVNS1ABP MYO18A GUK1 VCL NCKIPSD SLC5A11 VAMP1 AKR1E2 CAMK1 S1PR3 LIMD1 BAMBI PFKFB3 POLD2 DCXR SLC29A1 CCDC124 SPRED3 PCBD1 LDOC1 DDB2 PLCD4 VAV3 PLEKHH2 FAM13A SYT13 GRB7 FLJ45513 KLF7 HTR1D ANKRD1 LENG8 TNFSF15 ZNF618 PIK3C2B AKR1B10 TMEM139 DOK4 PCDH9 BCL2L12 PIGT GIP TMEM221 ITGA11 ADAMTS6 WISP2 DGAT2 AJUBA PTMS ACTN4 ALDH3A1 HLA-DMB CPNE2 NUDT1 TRNP1 PVRIG SFXN3 FTX IRAK1BP1 AHSA2 GOLGA8A LAMB2 AHNAK2 LIG1 KIAA0100 TMEM107 ZNF713 EMP1 HIST1H2BO HOGA1 PDXK GPR56 HEXIM2 FLRT2 CBS DENND3 LMCD1 LINC00319 APBA1 PKD1L2 MIR181A2HG MMP24 RSPH1 ABCA12 ADRA1B SCUBE3 ADD2 ANP32A-IT1 HOXB13 ITIH4 TBXAS1 DOT1L SMG6 ARRB1 USP5 MOB3A PRKCA PRPF6 ANKRD18A PDE6A ALDH3A2 AHNAK ALDH3B1 AVPI1 HRNR GAB2 ABHD4 PARP6 SLFNL1-AS1 CDK10 RAP1GAP PGPEP1 CYB5RL IGSF9B HOXB-AS3 SYNE1 LOC646762 MATN2 PTCH2 MARCH4 CHST3 PHLDB1 UCKL1-AS1 KLHDC7A SMPD3 KLC4 PTPN18 WIPF1 CPLX2 G6PD MADD ATP6V0A1 VPS13D KANK2 TCF25 NISCH TBCD HEXIM1 PC PPARA GP1BA GRK4 ADCY1 SEMA4G MPDZ CEL GREB1 GLIPR1L2 LRTOMT CYTH2 ANKAR GEMIN8P4 SYNJ2 GRIN2B FOXA2 SCARA3 ERCC2 NCAM1 C10ORF54 GIT2 GBF1 SLC22A5 BAAT ALOX12 LCAT SYNPO ANAPC1 ZNF142 FLNB BCAM PTRF RNASEH2C EHD2 PDDC1 LRIG2 RAB11FIP1 KIF12 PCYT2 AGFG2 GALNT10 VPS26B AFAP1 FAHD2A KLHL4 MTSS1L ANKMY1 PPP1R3C ZNF608 SRGAP3 ZNF488 KCNH1 FAM228B C1QTNF6 GTF3C1 MYRF RNF40 HNF1A-AS1 LGR4 OSBPL10 TNRC6A VARS2 DCAF11 KIAA0754 CACNG8 H1FX-AS1 HIF1AN MAPRE2 KSR2 PRR7-AS1 RPL32P3 MPRIP GABBR1 CACNG4 PDE1C ACAD8 SIDT2 LOC100129034 FRAS1 ADCY9 PDLIM7 STK32B CLASRP DCDC2 RDH5 LSM10 KIAA0513 MMP28 CDR2L ACACB ELOF1 TUBG2 COPS7B GOLGA2P5 ZNF738 PABPC1L APBB3 TMSB4Y TANGO2 RNASEH1 XPO7 PCYT1A PPP2R4 SMG5 ZSWIM1 SLC25A53 CRCP PAR5 DCTN1 MINK1 LOC100131691 LINC00085 PI4KA FOXD2-AS1 PPYR1 SOGA2 FN3KRP ELFN2 LINC00842 SDCCAG8 EIF5AL1 FUT10 BTBD19 SSBP4 TESK1 C1ORF86 ME3 LOC100130417 TSSK3 KAT6B ZNF512B NEIL1 LPIN3 TSSK4 SYT15 PROB1 GATS SLC25A19 ARHGAP11B EYS C6ORF89 ZNF425 CNTNAP3B MAPKBP1 ZNF117 ATP8B3 ARL17A POMT2 TTLL3 POLR2J3 ALPK2 SPDYE5 SNAP91 KIAA1199 LOC388692 LINC00261 SYT2 FAM63A RASGRF1 SNORD87 LOC401320 CTIF NEURL2 LOC100131096 GNAT2 LRRC6 RNF220 MAML3 ZNF767 CCDC136 ZNF789 LOC100128398 STAG3L2 MIR3916 C11ORF92 STAG3L3 SPTY2D1-AS1 BAIAP2-AS1 LOC100289137 LOC283922 PRRT3-AS1 PHF17 ACVR2B-AS1 NBPF15 GUSBP2 FLJ38109 FLJ45340 SRCRB4D DPY19L2P1 ARMC9 FBXO17 APITD1 BDNF-AS DIS3L2 IFT172 CUL7 LOC100131067 ANKRD36 C10ORF107 SNHG4 AGK ZNF726 LOC100131434 LRRC37A4P FAM105B EVC RCCD1 LOC284751 LMO1 PDE8B C10ORF68 LOC100272228 500 genes up-regulated by SARS-CoV-2 in human NHBE cells from GSE147507 mock v SARS-CoV-2 NHBE GSE147507 up MAOA IL1B BIRC3 IL6 MAPK3 HYOU1 TNF CXCL5 PPP2R1A MOGS DDX58 IL1A RRP9 IFITM3 MAST4 CXCL16 ANXA3 IFITM1 PGLYRP4 LYN NEDD9 TUBB4B LAP3 TUBA1A SMAD3 NFKB1 OAS1 TUBA1C ATP1B1 FN1 TUBA4A STAT1 TRIM25 TRAF3 IFITM2 EPB41L3 USP54 PLAT MSN CXCL2 ISG15 CSF2 MX1 SIPA1L1 ZC3H12C HYI AFAP1L1 TLCD1 ALDH1A3 BCL2A1 MYO10 MUC21 CXCL1 CXCL6 ASS1 ENTPD3 MYO1B IFI27 KRT4 KRT17 TTC9 S100P DUOX2 OSMR SERPINB2 SPRR1A SPRR2D EVA1C PRDM1 CRCT1 ADAM28 SLPI NDRG2 SGPP2 LCN2 GABRP SPRR1B RELT OGDH TNFAIP2 TOR1B HBEGF TYMP BST2 ITGA5 ACLY NLRP1 CCT5 PNP SDC4 MRPL12 TUBG1 GLRX LDLR IFI44 CES1 EPSTI1 SMTN PDIA5 ALOX15B SH3PXD2B ARNTL2 PRELID1 SLC43A3 IL7R G0S2 PTGS2 AKAP12 IGFBP3 B4GALT1 SLC2A6 B4GALT2 MYC BMP2 MMP1 SERHL2 STAT5A EDN1 PLAUR GJB3 RHOV LAMB3 WWC1 SEMA4B SULT2B1 TRIM16 FAM83G EREG WNT7A MAP2K3 MLLT11 UPP1 CTSC FAM50A BCL3 HELZ2 NUAK2 HSD11B1 SBNO2 SAA1 OAS3 IRF7 CFB GBP5 TNFSF14 TAP1 CCL20 LPXN IFIT1 GPR176 CORO1A SLAMF9 IL36G S100A9 IFIT3 OAS2 C3 XAF1 CXCL3 PSMB8 C1R KYNU IL1RN MRGPRX3 UPK2 PTAFR TGM1 HERC6 IFIH1 MLKL HAS3 STAT2 PML SOCS3 NFKBIE NAMPT RHCG PARP9 PARP12 SAMD9L HSH2D TMEM171 XDH PTGES SERPINA3 LIPG INHBA IFI35 PARP14 FOSL1 SAMHD1 F3 CSTA UBE2L6 ANGPTL4 PLAU FST CSF3 ETS1 PSME2 IER3 TUBA1B DUSP1 TGM2 HMGCS1 ICAM1 DTX3L NFKBIA IRF9 PSMB9 DRAM1 VEGFA BTG1 IFI44L PFDN6 TUBB CD74 ATF4 PQBP1 FXYD5 ERRFI1 TUBB2A PDPN EHD1 FNDC3B ANXA1 ELOVL1 EFHD2 SAT1 MARCKSL1 RFTN1 TMEM147 POU2F2 ZC3H12A FAM167A PPP1R15A TRIML2 FUT2 S100A12 MYPN TNFAIP3 ASB2 SERPINB4 PLA2G4C ARHGAP25 STC1 LIF CSRNP1 MAFF NFKBIZ ALAS1 PDZK1IP1 HMGB3 MMP10 SRM C1ORF74 PI3 HSD17B2 CCT7 AKR1B1 NAA10 TUFM ARG2 CDC25B RANGAP1 EFNA1 SAMD4A TNFSF15 HYAL1 RIPK3 HDGF SQLE HIVEP2 MMP9 NEURL1B C15ORF48 RND1 VEGFC CSRP1 STAP2 TAP2 S100A8 SLFN5 TLR2 MMP13 SMOX TRIM21 BID TRIM14 MAP3K8 MAP2K1 IRAK2 PCSK9 VNN1 IFI6 IL32 LAMP3 TFPI2 SLC25A28 LGALS9 MX2 ADRB2 KIAA0100 PSTPIP2 GJB2 LAMC2 KRT16 RELB MICB TICAM1 DUSP4 PRSS3 COPG1 CSTB N4BP1 RBMS2 C1S SOD2 SH3KBP1 TRIB2 MVB12A BPGM GTPBP2 ENO2 ACTN1 SERPINB1 CDA LTB P2RY6 KRT6B CHST2 ZBED2 CDC42EP2 SERPINB8 SEMA7A ITGB3 COL12A1 ADAM19 TUBB3 IVL ADAM8 PLSCR1 SPRR2E KRT24 SPRY4 SAA2 NCOA7 SLC6A14 C1QTNF1 ZFP57 CWH43 VNN3 SLC13A5 IFNGR1 GNA12 MTSS1 IKBKE USB1 IDI1 NAGK TNIP1 NCF2 PRMT1 OTUB2 IFNGR2 NFKB2 HMOX2 CD82 NECAP2 PSMC3 TNFAIP1 STK10 PPP4R1 IRAK3 ARF4 CD99 HEPHL1 KRT75 STK25 TINF2 TPCN1 ST3GAL5 PLEK2 EPHA2 BTG3 CDCP1 PLK3 FLII PODXL LSS MYEOV HCAR3 DAPP1 HDAC7 RRP1 E2F4 PPP1R14B PXDN LETM1 CTPS1 UCK2 PSMD2 FDPS MICA TNIP2 TNFRSF10A RAET1L DTX2 AMPD3 FUT3 CDC34 TGFA SEMA6A FERMT1 PDGFB PLEKHG7 MYO1C BIK ADAMTSL4 HK2 ZNF169 ULBP2 OSBP2 CYP27B1 TNC POLB PPIF POLR3E STARD5 SLC11A2 RHOC ARHGEF2 AHCYL2 TMEM51 KRT23 FLNB ANXA9 KLHL18 NOP2 SH3RF2 ZNF319 CEACAM19 ZSWIM4 C6ORF223 FSTL3 SLC25A37 RAB11FIP1 NRCAM DHCR7 THSD1 ISG20L2 MPV17L2 NBPF14 IZUMO4 PWP2 N4BP3 CSGALNACT1 RHOF MICAL2 FAM83A HHIPL1 FEZ1 GJB4 ANXA6 CDRT1 MRPS21 LGALSL CARHSP1 FHDC1 S100A7 TGM5 SHB RNF122 RBFA ZP3 C15ORF62 SPRR2A GNA15 PRELID2 CSNK1E LIG3 KIF3C AFAP1 COL8A1 MFSD2A STOML1 ZG16B DDX28 B4GALNT2 CCDC24 FAHD2A NCCRP1 NDUFB8 KCTD11 TRIM47 LTBP2 IGFL1 TEPP FNDC4 PID1 500 genes down-regulated by SARS-CoV-2 in human NHBE cells from GSE147507 mock v SARS-CoV-2 NHBE GSE147507 down PIK3R2 CNTRL PTEN MME TP53AIP1 SCN2B HOOK1 CENPF VIPR1 CEP68 NCKAP5 ITGA4 PTPN4 PLEKHA5 CREBL2 SCP2 NUDT12 MPP7 METTL7A PMS1 UNC119B CPT1A GPR155 IPP CAV1 RNF128 SLITRK6 CLCA4 OSBPL6 RPL9 SLC15A2 C1ORF21 FGFR2 GULP1 MT1E SMPDL3A PBX1 RHOBTB3 TRIM2 SOX2 DSG2 PLCE1 FAM214A TET2 CYBRD1 SATB1 SYTL5 WDR63 KRT15 PRSS16 MUC16 CLCA2 FMN1 ZNF507 RPL39 SSBP2 EXPH5 PRSS23 EYA1 MBNL2 ABLIM1 PSCA PTPRZ1 ANK3 GCNT4 VTCN1 SEL1L AQP3 PROS1 RHOB ABHD2 TOP2A CCNA2 LMNB1 CREG1 NREP SCPEP1 FRRS1 DEPDC1B HMMR ADPRH ARHGAP29 FKBP5 DLGAP5 GPNMB CDK1 CCNB1 ANLN OLFML2A CBR1 EPS8 CEP55 CERS6 KCNMA1 GNPDA1 ZNF365 ENPP5 PER3 FAM131B PTPRS TCN1 CAMK2N1 BMP7 PKD2 ZNF189 BMP4 ZNF180 CHURC1 FOXO1 IMPA2 MLPH SYT8 APPBP2 DSG3 WLS FZD1 KITLG CLU PRICKLE1 SFRP1 FRAT1 MAF EGFL6 TMEM60 FGF1 NR2F2 F2R DCK SOX6 TBC1D8 SORL1 MAB21L1 MEF2A ERF SMC2 CENPA CREG2 FANCI APOD SLAMF7 CKAP2 CENPP CENPE GEN1 SLC7A8 CD86 POLE2 FAM181B AAK1 STON1 LGI3 IGFBP6 NFIL3 SLC7A11 GBP6 TLR3 MAMDC2 CALML3 ZNF704 DBP ACER2 THBD SPARC ANAPC13 HPGD NPNT LIMCH1 CTSH PDE5A NR1D2 TP53INP1 PDCD4 TMEM50B TSC22D3 SP3 DYNLT3 RGCC MYLK MYLIP TCF4 GNS LXN NRP1 CETN3 CD36 TNNI2 DEK ARRDC4 ADAM32 RAB30 MXRA5 CCND2 C21ORF91 HMGN5 CYP4F3 FLRT3 IRF2BPL DLG2 CCDC58 SERINC1 HSF2 CXXC5 PPP1CC EXTL2 LCLAT1 LRP11 AGPAT5 GNA13 DNAJB4 SOAT1 VAV3 SGMS2 DUSP10 SKA2 APOBEC3C PPM1H MN1 PRR15 CREBRF SPESP1 ELOVL4 TRIAP1 ABHD10 C2ORF81 LGALS8 PDK4 FAM161A POU2AF1 MUC20 CCDC15 ALDH3A1 FBLN2 NID1 GOLGA8B PTGR2 SYT16 BBOX1 MT1X MCM4 ZNF566 MBNL3 SMC3 WDHD1 SLC26A2 SMAD5 SEMA3E PRPS2 SCOC PIK3R1 PCYOX1 C1ORF210 ATRX ZNF468 PRKACB FNIP1 ANKRD12 FAM110C WEE1 RRAGD BLNK RPL17 PUM2 ADD3 ZNF397 SESN1 CEP152 KLHDC8B PIK3R3 FLRT2 FRY FHL2 CHKA NT5DC3 PLA2G4F APBA1 CXCL14 DSC2 KRT6C STK32A TGFB3 NHLH2 POT1 AASDHPPT RMDN1 NANOS1 CAMK2D BACE1 EEA1 HFE PPARGC1A TIMP3 FAM111A RNF11 ARRB1 IFITM10 SLC35F5 GALNT1 SCD5 ALAD CITED2 ALDH3A2 GGCT EPHA4 ATP7A ZNF268 PPAT ANKH SYNE1 STOX2 PRODH CYB561D1 EPHB3 ACSL1 PPDPF DST SASH1 HIPK2 IL6R PRCP GHR MTUS1 GCLC HSD17B3 SYDE2 ADCY1 CPA4 SCNN1B MEGF9 TRMT1L FAM13C TCHHL1 SERPINB13 CDH10 JMJD1C CDK19 PCM1 TMEM168 ANKAR HLCS GSR BCL2L11 SLC9A9 WDFY1 RAB26 FBXW7 TMEM106B SESN3 ATG9B TBC1D15 SPTLC3 FMO5 MAP3K2 LMO4 SENP8 RANBP6 ZCCHC10 ZNF639 TSEN15 CLDN23 CTDSPL PALMD LYST TIAM2 TNKS2 CAPS MAOB GAMT STRBP TLL2 MIER3 LOXL4 MYSM1 CCDC60 TINCR DIP2B KLHL4 UBA5 EPGN TMEM135 MANBA LYPLAL1 NFIX PFKFB2 SLC44A5 REV3L TENM3 FPGT DSC3 SEMA6D PXMP4 LINC00672 UFL1 ACVR1 TBC1D5 MAN1A2 TFCP2L1 DZIP3 ZNF395 VSNL1 DPY19L4 LCA5 MAP7D2 PUS10 PGAP1 ESPN EFCAB7 CCDC121 DCAF17 ANKRD50 ENDOD1 ARHGEF6 RNPC3 LANCL1 VANGL2 EBAG9 KPRP MBOAT1 ZBTB7C PTAR1 NMRK1 CPD SLK FAT2 DCUN1D1 DTD2 UBN2 RBM20 SULF2 CPE PHTF2 TMEM131 SSX2IP SLC35D1 PARD6G KLHL13 ZXDA TUSC3 RAB15 ANKMY1 PADI3 ADAM23 FAT4 VWA8 FAM43A CCDC6 STK17B PPP1R3C CASD1 TLK1 CAPN7 ZNF579 ZNF607 ZNF608 MAN1C1 FRMD5 GPSM2 VGLL3 CNTNAP3 HEG1 STON2 LY6D PINLYP PCDH7 PHIP MFAP3 NCR3LG1 DENND4C UST PGRMC2 CCDC126 MANEA C8ORF37 ABHD13 CMYA5 YTHDC2 LPCAT3 AEBP2 CEP44 CRNKL1 CCDC138 LMBRD2 SRGAP3 CD109 ZNF718 MCOLN3 GXYLT1 FAM171B EIF4EBP2 ZNF488 CCDC14 JMY PRKAB2 PCDHGB5 IYD KIAA1109 SPATA6 LYRM7 ZNF273 SPIN3 C8ORF44 500 genes up-regulated by SARS-CoV-2 in human A549 cells from GSE147507 mock v SARS-CoV-2 A549 Series2 GSE147507 up TM4SF20 SUMO1 IL1B TBCA HDAC2 RSRC2 IL6 HSPA5 CCL5 SUMO2 UGT1A7 NMI NUP54 CXCL5 SLC27A2 ITGB1 DDX5 DDX58 EIF2S1 IL1A DDX21 SHQ1 IFITM3 SLU7 TPM4 ANXA3 IFITM1 AP3B1 DDX1 HSPA4 HLA-B LAP3 EHBP1 HSP90AA1 LARP7 FAM162A NCK1 OAS1 RDX HLA-C FN1 PLOD2 STAT1 TRIM25 IFITM2 B2M PRIM1 EIF2AK2 USP48 OASL EIF4E CXCL2 PPIG ISG15 FRMD3 PAICS MX1 MYD88 NOL7 UBE2E1 RBM39 PAIP1 CD55 BCL2A1 MNAT1 SLITRK6 CP CXCL1 KRT18 RPL9 ASS1 MYO1B IFI27 DUSP16 TNS4 CFH C1ORF116 EVA1C SEMA3A SLPI ZNF467 ISG20 LCN2 AGR2 EHF TAB2 PARP10 LGALS3BP APOL1 PIGK TYMP BST2 SLC16A3 RHOB EXO1 C5 HSD17B4 IFI44 EAF2 FAM72D CCT8 LTA4H SLFN11 CEP55 BATF2 LDHA CA11 PTGS2 FAM131B IGFBP3 ZNF184 KLF10 CDH1 EDN1 PSMD6 SULT2B1 EREG DKK1 GMPS NUCB2 HIF1A HELZ2 HSD11B1 PDLIM5 SMARCA1 SAA1 OAS3 IRF7 CFB FANCI NLRC5 TAP1 CCL20 ERCC6L CKAP2 IFIT1 STAT4 CTSS MASTL TNNI3 IFIT3 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 PSMB8 APOL6 C1R KYNU USP18 CMPK2 IFIT2 IFI16 CLEC4E FGL1 HERC6 IFIH1 CCDC18 STAT2 STON1 CACNA1G PML PLEKHA4 FGG ADAR NAMPT PARP9 PARP12 SAMD9L SERPINA3 IFI35 PARP14 HAS2 SAMHD1 UBE2L6 UBA7 SP110 CSF3 RBP7 TSC22D1 PSME1 PSME2 THBD UQCRB IER3 ICAM1 DTX3L NFKBIA IRF9 GBP3 CYB5A PLIN2 EFEMP1 LUC7L3 IFI44L DNAJC8 PAIP2 BNIP3 FHL1 FDX1 CHORDC1 ERRFI1 DNAJA1 PSMA6 FSTL1 ANXA1 SELENBP1 THEMIS2 PHLDB2 SAT1 SUB1 SET CACYBP DEK ESF1 FGB AOX1 SYT1 SERPINI1 PTGER2 TNFAIP3 STC1 FLRT3 TAF1D ZNFX1 SNRPG HAT1 SUPT16H MMP10 PSMA4 HSP90B1 SARNP CNOT10 MTX2 TTC1 SUCLA2 CCDC58 NOP58 PI3 ANP32E PCNA C2ORF74 MSH2 SMARCA5 ZDHHC6 PAM GJA1 SSB STEAP1 BZW1 RPAP3 TMPO PNPT1 MAP4K3 AKR1B1 CBX1 USO1 GNL2 CWC22 ERVMER34-1 MXI1 MORC4 CCDC117 TCP1 INTS6 PDE4B ITIH2 ID1 MNS1 GSPT2 PIR MAP2 C15ORF48 GLCE SERPINB7 MLXIPL ODF3B MKKS NNMT TAP2 EBI3 TRIM21 RNF31 CREM ZC3HAV1 TDRD7 TRIM14 PDK4 MAP3K8 MORC3 ELOVL6 OLR1 TESC IFI6 PTGR2 PRPF38B BMPER IL32 PSIP1 LAMP3 DDX60 SMC3 WDHD1 TPR CCDC77 TFPI2 DNAJC7 SP100 IFIT5 HERC5 TRANK1 RPL22L1 DDX60L SAMD9 USP44 GBP1 CASP7 EIF5B GINM1 XPOT ZNF624 IGFBP1 CCDC91 XRCC4 THOC2 PLK2 CTNNAL1 NOSTRIN NUDCD1 SP140L C1S SOD2 TRIM38 BLZF1 CA9 MMD CASP8 MBD2 ADAM10 TRIB1 STK17A PAPPA TMEM130 PLSCR1 NCOA7 RARRES1 IFNGR1 PGK1 ORC2 TANK MLLT3 B4GALNT4 GRSF1 FKBP14 AK3 APIP SNRNP27 MCFD2 DMC1 POLR3G FIP1L1 FAM114A2 KTN1 KCNJ2 NEMF SNAP25 REV1 BCCIP C9ORF64 LTV1 ZCCHC7 NSRP1 SLC10A7 MSH6 CLDN1 TIGD2 CEP63 STAU2 VEZT GPCPD1 RBP4 ERAP1 MED6 DDX50 USP8 RBBP6 REC8 KIN SYCP2L EIF2AK1 SMIM3 CUL3 BBIP1 NYAP1 NFYB U2SURP DNAJB11 USP53 C4BPA PTER NT5C2 ZC3H15 RPF1 DNTTIP2 PTP4A1 EIF3J PDIA3 ARHGAP24 ALDOC ZNF430 ACSL4 BTG3 ZNF326 GNL3 DPM1 USP3 KCNJ6 KRT222 DNAJC21 PON2 FILIP1 GTF2E2 MTA3 CEBPZ ZFP28 STT3B PRAME TXLNG ZNF558 C2CD4C SNAPC1 USP16 WDR75 CCAR1 CBWD2 ELAC1 TMEM123 WDR43 SOCS6 ANKEF1 SUSD2 PTCD3 AKAP10 PNMA2 SLC39A8 DNAJC2 CCNYL1 P4HA1 BRIX1 GTPBP10 PDE1A WBP4 DHX29 SPATS2 ZSCAN30 HSPB11 PTPN2 CCNT2 TEX9 ZNF518B HNRNPD HERC4 MRPL33 ANKMY2 PTPN12 PLA2G4A ING2 THEM4 GOLGA4 TIGD7 CPSF3 SMIM13 HLTF CWC15 TMCC1 KCTD6 FGA LLPH IFT81 SHOX2 SMS LRRC49 ZMYM2 CPS1 ZNF680 RIOK1 CDCP1 THOC7 PPAT PPP2R2A MIOS GREM1 NUP62CL GABRA5 CTTNBP2 ZNF239 INTS8 PCDHGB4 500 genes down-regulated by SARS-CoV-2 in human A549 cells from GSE147507 mock v SARS-CoV-2 A549 Series2 GSE147507 down SLC36A1 PTPN14 MVP ANPEP SQSTM1 SPTAN1 FBXW5 STX3 PPP2R1A TRIB3 TSPO SLC16A8 SLC22A18 A4GNT PMEPA1 ADA NPTX1 SIRPA SLC9A3 HMOX1 SERPINE1 TCN2 MTMR11 COL4A2 CTSD COL4A4 SFN MGAT4B RETSAT MEPCE PEPD PXN ZNF575 PLB1 TLN2 FRMD8 PLEC NEU1 MXRA8 ADHFE1 PLEKHA7 SAT2 GSTZ1 SAC3D1 NAGLU NT5DC2 KRT4 RAB40B NDUFB2 KIAA1217 MZT2A FNIP2 SLC2A1 TAGLN2 IFFO1 NADSYN1 MAPK8IP3 ATG16L2 VPS37C ARHGEF10L HS1BP3 GIGYF1 VASH1 DNAJB2 CAD CORO1B CIC LMNA URM1 ORAI2 NDST1 KCNAB2 INF2 TOLLIP SLC1A5 ABHD2 SLC38A7 MARVELD1 CORO2B MAFG SAPCD2 UAP1L1 TP53I3 TRPM2 SNX8 KCNMA1 PRELID1 GNPDA1 TNRC6C MSC YPEL1 SOX13 LLGL2 COL1A1 CILP2 PKD1 EP400 ABCG1 SREBF1 AP1M2 THEM6 CEP170B CARD14 PPP1R37 RHOD WNT4 WNT9A NAV2 DVL2 DACT1 ARHGAP1 HERC2 RGS3 UPP1 TRIOBP DYRK1B NBEAL2 RERE RNF44 CYHR1 SLC12A7 MNT LFNG ULK1 SETD1B ATG2A MXD3 STAG3 PODNL1 IQGAP3 PREX1 PHF19 EFNA2 IGDCC4 LRFN4 AKR1A1 ADAMTS15 RPL10 TAGLN ISCU NUPR1 NSMF VIM SH3PXD2A IL3RA PSAP MXD4 PIGQ WNK1 LBH PSKH1 FASN TPRG1L GEM FAM43B DDIT3 SLC25A25 TGFB1I1 DGKQ PPP1R15A QRICH2 COL20A1 PLA2G4C RTN4R VASN FOXK1 L3MBTL1 CLN8 BBC3 NEURL3 FAM161B CHAC1 WBP2 ATP6V0E2 CIB1 TMEM208 PTRHD1 ATP6V0D1 COPRS SPRED3 DCTN3 TIMP2 WDR83OS SUSD5 CXXC5 BEX2 CDK4 ARHGEF18 PLEKHG6 SRPK3 PPM1H LENG8 COL7A1 VEGFB ITPKC NDRG4 NEURL1B BTBD11 PRRT2 MAP3K14 CHRNB4 FAM110A ITGA11 GJD3 CCDC78 GRIN2C C19ORF71 SSNA1 ACAP1 GCAT SLC1A4 CDKN2C CYP4F11 PVRIG TESK2 CLDN14 ACP6 SMG1 LONRF2 PLEKHA6 PDZK1 AHNAK2 CNNM3 ZBED1 TCTA TPRA1 DCST2 HERC1 TRPV1 ETS2 RRAGD VAT1 CERK COPE DYSF SNN PDXK MEX3B BMF LMCD1 LPIN1 ZNF469 OSGIN1 TNFRSF10D ADAM19 DPYSL3 NUMBL ESPNL ADRA1B IRAK1 HPS1 DOK3 NPC1 AGO2 IFITM10 CARS2 COQ4 RYR3 SLC35A4 GNG3 NXNL2 AP5Z1 AHNAK CLCN7 ALDH3B1 LTB4R PLEKHJ1 ABHD4 ANKRD11 NACC2 FLCN TSPAN1 INPP5E CDH4 NDOR1 NPAS1 DMPK CDK10 DLL4 SPNS1 HMGXB3 TBL3 ACTR1B CAMKK1 KLHL21 COMTD1 PMF1 OBSL1 SCNN1D MEGF6 MEF2D RAP1GAP FBXW9 HTT JRK SGK2 KCTD7 ANKH ARID1B MZT2B AACS CEMP1 PAPLN MAP3K3 KCNC4 ADCK5 PRKAR1B ART5 HMG20B PINK1 ZNF524 ATXN1 TSPAN10 WDR81 FIZ1 BCAT2 PGPEP1 BOLA1 TEP1 CYB5RL TRIP6 TMEM91 PLCXD2 IGSF9B CCDC17 GGN PCDHA11 SYNE1 MDGA1 SLC16A13 ACAP3 ADI1 NEU4 ZNF324B ZHX2 PEX10 RALY RAB40A DUS3L PCDHA12 ULK3 PRSS53 HAPLN3 PCDHAC1 PPP1R3B CLTB MATN2 FAT1 DGCR6L GPRC5C PLEKHM1 HOXB6 STOX2 EEPD1 ABCB6 PTCH2 P2RY2 DDA1 PLK3 BEST3 ITPA VPS18 HECTD3 PEMT SHH GAL HDAC5 FLII OTUD7A NOXO1 PRODH NR0B1 CHST3 APC2 IPO13 ENG NLGN3 EML5 TSTA3 NUDT17 PODXL LRP3 UNKL AKAP13 RABEP2 P4HTM TRAPPC6A POLE4 CHGA GLI4 PACS2 PRIMA1 SYNE2 AMH PHLDB1 GNPTG KIRREL3 MAZ COL27A1 KCTD15 FA2H ATP9A SYNM NUDT14 SIRT7 SLC39A13 FBXL8 MLXIP LSS BAIAP2 TTLL12 RNF224 STX1B TAF1C THOC6 ZNF219 FAM102A MYEOV BTBD9 MVK SMPD1 AMDHD2 METRN FDXR KLHDC7A NCOR2 ASB1 IGLON5 RNPEPL1 CAPN10 TRABD2B SMPD3 POLR2A FBXO10 PANX2 PRADC1 SH2D5 CYB561D1 ATP13A1 CRTC1 SMIM5 MBD3 TET3 RPS19BP1 FBRSL1 FAM174B ARFGAP2 DSCAML1 FASTK NIPAL4 PCDHGC3 MZF1 MFSD12 MRPL54 C10ORF95 MPC1 PRRT3 TBC1D7 RHOBTB2 KLC4 METTL22 NOX1 ZFYVE26 ADCY5 DDX39A SFRP5 PTPN18 SLC34A3 RNF185 MSI2 ALDH16A1 TELO2 SLC37A4 TMEM129 EPHB3 PDRG1 ZNF785 KATNB1 MFNG REPIN1 NECAB2 LIPC HDAC4 PLXNA1 PGP ZFYVE1 TEX22 ASIC3 RPS6KB2 AIFM2 FSTL3 HES6 C1QTNF6 MGAT5B IDS TBC1D16 TPCN2 TTC21A TMEM8B POMT2 500 genes up-regulated by SARS-CoV-2 in human A549 cells from GSE147507 mock v SARS-CoV-2 A549 Series5 GSE147507 up NKX3-1 F2RL1 PPIL3 BIRC3 IL6 CCL2 CCL5 DDX10 VDR CXCL5 ITGB1 TRIB3 PCK2 IL1A ASAP2 DAAM1 IL17RD TIMM9 ANXA3 ATXN3 HLA-B KLF6 SMAD3 NCK1 UGGT2 SERPINE1 FRMD6 MID2 PTX3 INHBE ADAM17 CLIP4 FYN CXCL2 CD8A CSF2 DPH5 STC2 NAP1L1 UBE2E1 ZC3H12C VLDLR CD55 POLI ALDH1A3 ZFAND1 BCL2A1 MT2A CXCL1 SLC16A9 ITGA2 ASS1 EXT1 NT5E RAI14 SYTL2 CA8 OSMR DSG2 TCP11L2 GADD45A RND3 ZNF507 EXPH5 HTRA1 ABCA1 PLEKHG1 TNFAIP2 ITGAX HBEGF TYMP ITGA5 CLTCL1 SDC4 ALDH1L2 SCARB2 BCAT1 LAMC1 IL18 EPHB2 GRB10 KCNMA1 ARNTL2 MTHFD2 AKT3 AKAP12 AZIN1 TUFT1 ZNF185 RUNX2 KLF11 CDV3 GADD45B AXL CYP4V2 CHURC1 PLAUR CHMP4C LAMB3 SLC38A1 ITPR3 BNC2 EREG SORCS2 FOXL1 ATF3 GABARAPL1 F2R UPP1 CFB TNFRSF9 CCL20 ULBP1 VAV1 GLIPR1 CRMP1 CTSS PSAT1 LACC1 C3 CXCL3 APOL6 GBP4 C1R CLEC4E NAV3 IFIH1 SOCS3 GBP2 RHCG SAMD9L XDH SLC7A11 SERPINA3 PARP14 FOSL1 PARP11 GFPT2 PLAU IGDCC4 SLC6A15 CLIC4 ETS1 IER3 MAP1LC3B DUSP1 R3HDM2 TXNIP ICAM1 DTX3L EIF2S3 KLHL5 PXDC1 GBP3 JUN SEMA3C DRAM1 VEGFA DMKN EIF3E EFEMP1 BTG1 SERPINE2 LIMCH1 PDE5A NR1D2 KLF9 TSC22D3 FHL1 RBMS3 IL3RA ATF4 FEZ2 FSTL1 PHLDA1 PHLDB2 SAT1 SLC38A2 ARRDC4 KDM6B CREB5 DDIT3 TRAF1 MBP BEST1 AOX1 PPP1R15A CSF1 SYT1 TNFAIP3 SERPINB4 PLA2G4C MAPRE3 MATN3 PPP1R15B LIF DUSP5 TIPARP CHAC1 TAF1D MAFF IL11 PDZK1IP1 MMP10 YPEL5 GJA1 EIF2A SERINC1 ELOVL7 LAMB1 SCG5 BEX2 DHRS2 MXI1 MXD1 ZBTB8A DNAJB9 KLF7 OGT SAMD4A MAP1B RRAGC CREBRF MAP2 C15ORF48 KDSR C3ORF52 MOSPD1 ITGAV CD47 SERPINB7 ABL2 RAP1GAP2 BEAN1 EBI3 VRK2 ASNS SLFN5 SMOX IL15 NALCN OLR1 IRAK2 AJUBA CCNB1IP1 CYP1B1 GOLGA8B ANKRA2 CLGN BMPER IL32 DDX60 MAN2A1 GALNT12 DDX60L UFM1 GBP1 ST3GAL1 TMEM159 KIF1A LIPH SMURF2 XPOT LAMC2 GFPT1 EMP1 TM6SF1 FMNL2 RELB NFE2L3 CTNNAL1 PMAIP1 RRAGD C1S SOD2 PARP8 SH3KBP1 OPTN CFLAR GTPBP2 SRGN EIF1 PRKCH SWT1 CBS PRKAG2 HRH1 PTPRE SESN2 LONRF1 SERPINB8 SEMA7A KIAA1549L COL12A1 SPOCD1 FGF2 CD68 NCOA7 C1QTNF1 MEIOB IFNGR1 CDH2 RTCA UBE2H TNIP1 GK NPC1 CDK6 ROS1 IFNGR2 NFKB2 NEDD4 EEF1A2 PHGDH CYTH1 TMEM167B CCPG1 PDP1 RIN2 PLEK2 ZCCHC7 CLDN1 GPCPD1 ERAP1 USP53 ZNF558 SOCS6 GTPBP10 PTPN2 PTPN12 CDCP1 GREM1 CDH4 PODXL KIRREL3 NIPAL4 ALPK1 LBP PXDN ABLIM3 PCDH1 LRIG1 HMGA2 PDGFA ITGA3 SGPL1 OCLN AMPD3 NPHS1 PRKCE CPM TGFA STK38L FOXP1 SALL4 HOMER2 DLG3 RRAS2 PDGFB DPY19L3 TMEM168 TNFRSF10B ATP2A3 DRAM2 FBXO32 TFPI NDUFA4L2 FUT1 FGD4 PLD1 ZNF621 ZNF449 ZNF641 WDR41 CLEC2D MTHFD1L ABCA10 PEAR1 SLC16A4 COL5A1 UGCG TSEN15 CDK7 SUPT3H AKNA OGFRL1 CSGALNACT2 ANTXR2 ARHGEF2 ALKBH8 FLNB TMEM87B SEL1L3 SLC4A7 FGD6 C20ORF194 SPIRE1 DLC1 L1CAM TUBE1 KIF21B UHRF1BP1 TTC39B ADM2 SLC25A37 HIVEP1 N4BP3 CSGALNACT1 B4GALNT2 LTBP2 LYPLAL1 ACVR1 NMRK1 HEG1 CEP120 CCDC50 DUS4L NHLRC3 LRRC8C FADS3 C11ORF54 KCNH1 HOXB9 MSANTD3 FHIT DOCK11 MCTP1 ZNF25 TES FAM228B ECM2 RASGRP2 RSL24D1 UFSP2 KIF5C IGF2BP2 SBF2 CLDND1 THG1L PYROXD1 SLC9A7 ICA1 TRPC1 KIAA0319 ZNF697 ZNF277 CLDN12 NABP1 KDM5B AGTPBP1 NTN4 CEBPG RASGRF2 TMX3 TMEM67 APBB2 TRIM36 GFRA1 TCEA1 SYNGR3 TOM1L1 SPRN ANK2 GALC NGEF IBTK TMEM156 ZC3H6 HORMAD1 THEG ZDBF2 THAP6 FAM149B1 C9ORF72 QPCT HSPA13 ZNF146 SNX24 ZFP90 CHST11 IFRD1 CAPRIN2 ANKRD28 CCBE1 ADPRM DNAH17 COL22A1 PPFIBP1 RAB39B GPD1L JMY CCDC90B CPAMD8 CLMP BTF3L4 NMD3 JOSD1 DNAJC10 TSPAN2 RAB3IP 500 genes down-regulated by SARS-CoV-2 in human A549 cells from GSE147507 mock v SARS-CoV-2 A549 Series5 GSE147507 down TM4SF20 UHRF1 DGAT1 KPNA2 SLC9A3R1 NUP62 ANKS4B CCND3 CYB5B TMEM97 PDZD3 PRR15L KHK TUBB4B GPAA1 NPTX1 HSP90AA1 HNF4A DNMT1 TST TUBA4A POR USH1C TRIM28 FOXA1 POLA2 PHB WFS1 SLC23A1 HSPA8 CAT THOP1 MUC13 FCGBP SFXN5 SLC25A39 FBXL6 POLRMT GADD45GIP1 FGFR4 ARHGAP18 WDR34 EXOSC4 IFT122 KRT18 NT5DC2 KRT4 GPX2 METTL7B CNN3 C1ORF116 BCAS1 CKS2 PRSS23 AGR2 KRT8 EMP2 TMEM109 SRRT UNC93B1 NACC1 TOMM40 TAOK2 EMC10 PPP6R1 MAP3K11 INF2 CLUH SNRNP70 NCLN PLK1 EXO1 DHCR24 MYBL2 TICRR ZWINT CLSPN TK1 TROAP EZH2 LMNB1 TUBG1 GTSE1 AURKB KIF18B SPR CDCA5 SPAG5 AP2S1 MCM2 KIF2C CDC25A AURKA ESPL1 KIAA0895L RRM2 SHMT1 PAQR4 CDC6 E2F1 BIRC5 ORC1 KIFC1 SAPCD2 GALK1 MCM10 SNAPIN GLDC TPX2 CCNB1 NCAPH CBR1 CDCA3 CDC20 PKMYT1 HJURP MKI67 CDC45 ALDH4A1 KIF20A DTL NCAPG TYMS ZNF574 UPK3B NCALD LLGL2 CHTF18 ZFP36L2 FOXM1 SREBF1 AP1M2 THEM6 TONSL PPP1R16A JUP MROH6 TSKU IFFO2 MYH14 SPDEF RHPN1 SLC4A2 CLU SFRP4 AXIN2 PRC1 MAP2K6 BIN1 CBX2 RNF26 NR2F1 EDC4 DACT2 NBEAL2 PITPNM1 MBOAT7 ERF E2F8 UBE2T MXD3 PASK RAD54L ESCO2 ASF1B KIF22 TCF19 GINS2 CHAF1B FAM83D NCAPD2 SPC24 TACC3 ERCC6L NUSAP1 MCM5 SPC25 ARHGEF39 CCNF POLE INCENP GINS1 PHF19 CHAF1A CCNE2 XRCC3 DHFR TIMELESS UNG CACNA1G TCIRG1 CLDN2 DIO2 EPHB6 TTYH3 PFN1 LY6E TUBA1B ATP6V0C BAG1 PEBP1 THRA HMGCS1 TPPP3 NDUFA3 U2AF2 ACAT2 PSMD3 TMEM160 SLC12A2 NDUFB7 LYPLA2 DHX30 CALR MPC2 RNPS1 PIGQ DNAJA1 SELENBP1 FASN MYO18A DBI SCAND1 CACYBP NTRK3 TBX3 SCARA5 VAMP1 RADIL IER5L UBE2S TM4SF4 HAT1 ATP6V0E2 RBM42 MIF CKB ATP6V0D1 SLC25A11 MAGED1 PCNA NOSIP POLR2E AHSA1 MFSD5 CXXC5 GMNN TUBB6 HSPA1A RAB1B SDF2L1 VAV3 RUVBL2 E2F7 TOB1 SRSF2 PRR15 GAS2L1 DOK4 HABP2 ATAD2 FANCG MCM6 PCDH9 DNAAF3 MVD BCL2L12 LRRC14 FEN1 ITGA11 RASD1 WDR90 SSNA1 PACSIN1 ISOC2 ACTN4 HLA-DMB CDKN2C PCSK9 MCM4 FAM111B MCM7 SNRNP25 MAD1L1 ALYREF RFC5 LRRC45 NEB LMNB2 APOBEC3B LIG1 NCAPD3 CDCA7L UCP2 BOP1 MLF2 HNRNPL ETS2 TRIM26 BRI3BP SERPINA6 AMPD2 NRGN PIK3R3 HPDL INSL4 ANAPC2 FADS2 NR4A1 OLFML3 FANCA RHBDL3 HOXB13 CCDC34 HSPA1B SDHA SNRPD3 IDI1 MRPS12 AP1B1 USP5 ALG3 VTN SLC35A4 CHMP1A AURKAIP1 CLN6 SLC25A10 DBF4B THAP7 DDX54 NUBP2 SUV39H1 IRF2BP1 CPS1 NDOR1 TBL3 RAP1GAP WDR81 ADI1 DGCR6L HOXB6 VPS18 LRP3 AMH SYNM LSS ZNF219 MVK METRN FDXR KLHDC7A PRADC1 MBD3 FASTK DDX39A ALDH16A1 TELO2 EPHB3 KATNB1 REPIN1 CPLX2 PLXND1 KANK2 SMPD4 NOC2L TBCD SIVA1 FDPS HEXIM1 TUBB4A APEX2 SHPK FDFT1 DHX9 MTUS1 CD320 INHBB EHMT2 DTYMK PGP GPC1 LRRC59 IGFLR1 RAB26 SCARA3 EMC6 MPP2 ABCB8 ICMT BAAT ADRA1D MCM3 PIN1 RRP36 THOC3 GTF3C5 PKN3 POLD1 MRPL4 RECQL4 RPUSD1 GEMIN4 IPO4 CENPO MMP15 ENO3 IMP3 RNASEH2C SLBP GINS4 POLR2L PEG10 MFSD3 RBM14 GPS1 KIF12 DHCR7 HS6ST1 NSDHL MMAB JMJD8 PCYT2 SLC22A18AS SLC25A1 NTHL1 EBP GMPPB PIF1 ANKRD54 TMEM201 C21ORF58 MPV17L2 ANXA6 HYAL2 PDK2 CNP PHRF1 RAVER1 TECR INTS5 WRAP53 ZNF703 C1QTNF6 SLC39A3 ZDHHC12 HCFC1 ZNF771 FBXL19 PDE3A ZNF672 CABLES2 CASKIN2 DGCR6 CLEC11A FAM222A C19ORF47 IGFBPL1 CACTIN DISP2 GTF3C1 MGAT5B ZBTB45 ZNF444 SAMD11 BRAT1 KCNK5 NOC4L TAF6L NOL12 HAUS5 RABL6 PDF EFCAB12 RFC3 MYRF TMEM53 RNF40 POP7 CXXC1 INTS1 TMEM104 VASH2 CPSF1 C1ORF159 AARS2 HSPBP1 ZNF787 RHOT2 FOXRED1 WDR62 GPRIN2 NR2F6 SP9 RNF43 ADAT3 RAD9A SLC27A3 MAPRE2 PUF60 500 genes up-regulated by SARS-CoV-2 in human Calu3 cells from GSE147507 mock v SARS-CoV-2 Calu3 GSE147507 up NKX3-1 IL1B RSRC2 SEC16B BIRC3 IL6 CCL2 CCL5 VCAM1 EGR1 UBD TMPRSS3 NMI TNF PCK2 DDX58 IL1A CXCL10 MAST4 IFITM1 LYN NEDD9 LAP3 ZNF274 JAK2 KLF6 SMAD3 IFNL3 NFKB1 SERPINE1 OAS1 PTX3 INHBE STAT1 TRIM25 IFITM2 PTPRH EIF2AK2 PLAT APOBEC3G OASL CXCL2 IFNB1 ISG15 NUB1 CSF2 STC2 MX1 MYD88 WFDC5 ZC3H12C NR3C1 LIFR KMO ALDH1A3 MT2A CXCL1 TGFB2 TNFSF10 KRT17 HES1 DUSP16 ZEB2 PARD6B NR4A2 S100P DUOX2 NFAT5 C6ORF132 KIAA1217 PNRC1 RICTOR SERPINB2 GADD45A RND3 ANKRD33B PRDM1 SEMA3A ISG20 ZBTB20 ZNF462 ARID5B TNFAIP2 PTGER4 PARP10 THBS1 HBEGF PTK2B TYMP BST2 B3GNT7 SLC15A3 SMAD7 ITGAM FBXO6 NLRP1 SDC4 LMO2 ALDH1L2 MACC1 ZBTB43 IFI44 EPSTI1 SPRY2 APOL4 BATF2 MTHFD2 RASGEF1B G0S2 PTGS2 LAMA2 GATA3 AKAP12 NUAK1 B4GALT5 CDKN1A TUFT1 BMP2 ZFP36L1 ZNF185 KLF10 ZFP36L2 GADD45B EDN1 PLAUR FOXO1 BCL9L TFAP2A DSG3 IRF6 SLC7A5 ZNF217 EREG SOX9 NAV2 FGF19 ATF3 JAG1 TNFRSF11B BCL3 FOSL2 HELZ2 NUAK2 RSAD2 OAS3 CD69 IDO1 IRF7 ZBP1 NLRC5 GBP5 TAP1 CCL20 ULBP1 IFIT1 SECTM1 CYP1A1 PSAT1 IFIT3 RTP4 HLA-F OAS2 C3 PHF11 XAF1 CXCL3 CH25H PSMB8 CD274 APOL6 GBP4 DHX58 C1R KYNU USP18 CMPK2 IFIT2 IFI16 PTAFR NAV3 HERC6 IFIH1 STAT2 PML PLEKHA4 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L HSH2D PIM1 INHBA RNF213 IFI35 PARP14 FOSL1 TRAFD1 SAMHD1 F3 UBE2L6 TLR3 PLAU UBA7 FST SP110 CSF3 SCN3A RIMKLB IRF2 ETS1 KLF4 ZFP36 IER3 IRF1 RASGRP3 DUSP1 TXNIP ICAM1 DTX3L NFKBIA IRF9 JUNB PSMB9 GBP3 JUN SLC34A2 VEGFA NR1D2 IFI44L SERPINB9 ARRDC3 ATF4 PIM3 JDP2 ERRFI1 CCNL1 THEMIS2 PHLDB2 SAT1 GEM RBM11 ARRDC4 KDM6B CREB5 SAMSN1 ZC3H12A LST1 DUSP8 TRAF1 EGR2 NR4A3 EDN2 IFNL1 PPP1R15A CSF1 TRIM22 SERPINA10 B3GNT5 C6ORF58 TNFAIP3 HDAC9 CYTH4 ZNF267 PLA2G4C FILIP1L TP53INP2 GIMAP2 BBC3 AMOTL2 PPP1R15B NEURL3 LIF DUSP5 IRS2 TIPARP CSRNP1 CHAC1 BHLHE40 MAFF NFKBIZ TSC22D2 SERTAD2 ZNFX1 FOXO3 FOSB SH2B3 DEPDC7 PNPT1 AMIGO2 MXD1 DNAJB4 DUSP10 PDE4B ANKRD1 EFNA1 SAMD4A TNFSF15 MAP1B CREBRF ITPKC HIVEP2 C15ORF48 RND1 SERPINB7 SIK1 ABL2 ASNS SLFN5 CASP1 PPM1K IL15RA ZCCHC2 MMP13 TRIM21 TRIM56 ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 MAP3K8 RIPK2 IL15 DDO IKZF3 IRAK2 AJUBA SLC1A4 CYP1B1 CXCL11 GSDMB PER1 IFNL2 LAMP3 DDX60 RNF19B LGALS9 TNFSF13B XRN1 SP100 BCL10 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 ADRB2 SAMD9 GBP1 ST3GAL1 TP53BP2 MB21D2 ETS2 CEACAM1 KLHDC7B HDX RELB RCAN1 ETV7 GMPR NFE2L3 PMAIP1 TICAM1 CX3CL1 SP140L APOL3 N4BP1 RBMS2 BTN3A1 C1S SOD2 TRIM38 RABGAP1L PARP8 IL12A PHACTR4 OPTN CFLAR GTPBP2 RAB8B SERPINB1 LTB RASGRP1 KRT6B DENND3 TRIB1 KIAA0040 BCAR3 BACH2 CLK1 JARID2 SEMA7A BACH1 KRTAP2-3 CALD1 PLSCR1 NR1D1 DUOXA2 NCOA7 C1QTNF1 CDC14A CCL22 BDKRB2 RIOK3 APOBEC3F TNIP1 NCF2 BCL2L14 SP8 XBP1 NFATC2 IFNGR2 PELI1 NFKB2 NEDD4 OTUD1 CYLD KCNJ15 CITED2 BHLHE41 PDP1 ZBTB10 GPCPD1 TMCC1 PPP2R2A DAPP1 MAP3K13 EPC1 SSH1 NLRP3 LRP2 FUT3 DUOX1 RREB1 KDM6A MUC4 DAB2IP CYP3A5 PDGFB PLEKHG7 CHD2 TNFRSF10B BCL2L11 FBXO32 CD22 NDUFA4L2 FUT1 FLT3LG CTH BTN2A2 KIF6 SAA4 SDS SYNPO UGCG SOX4 GATA6 LATS2 SPSB1 KRT23 FLNB TBC1D22B CSRNP2 TIAM2 DCP1A FGD6 SRFBP1 C18ORF25 PDZD2 DLC1 DEFB4A ZSWIM4 C6ORF223 SKIL KBTBD2 ARHGEF28 L1CAM BAHCC1 FSTL3 TUBE1 APOBEC3D KIF21B GSE1 CXORF38 UHRF1BP1 TTC39B LRRN3 CLK4 CNKSR3 ADM2 SLC25A37 RAB11FIP1 ZNF385C NRCAM HIVEP1 SYTL3 SHROOM2 500 genes down-regulated by SARS-CoV-2 in human Calu3 cells from GSE147507 mock v SARS-CoV-2 Calu3 GSE147507 down DCTPP1 TIMM8B UHRF1 MALL CISD3 KPNA2 SLC9A3R1 MME ANKS4B VIL1 CYB5B TMEM97 MIPEP PKM PRR15L TUBB4B CENPF SIGMAR1 AP2M1 TUBA1A CALM1 PMPCA ANXA13 ISYNA1 TSPAN8 PHB HSPA8 CAT THOP1 IGSF9 FBXO9 MDH1 CLDN10 FGFR4 WDR34 METTL7A IFT122 ASB9 SAC3D1 DHRS1 ENO1 SDC1 NT5DC2 FAM229B UPK1B TSPAN6 C9ORF116 METTL7B CRYM NDUFB2 AGR2 KRT8 EMP2 AADAT TSPAN3 PRPS1 TOMM40 STEAP3 VASH1 EIF3B ORAI2 EFTUD2 EMP3 ACLY NCLN PLK1 AK2 DHCR24 TOP2A TICRR ZWINT TROAP SAP30 MRPL12 LMNB1 GTSE1 CDKN3 UBE2C E2F2 KIF18B SPR SPAG5 AP2S1 ANXA5 BUB1B MCM2 KIF2C AURKA DLGAP5 ESPL1 CAPNS1 RRM2 SHMT1 CDC6 E2F1 BIRC5 ORC1 KIFC1 KIF4A MPND COMMD9 SAPCD2 ROGDI HSD17B10 SNAPIN CDCA2 NETO2 NME1 TPX2 CCNB1 NCAPH CDCA3 CDC20 KIF23 HJURP TRIP13 MKI67 CDC45 KIF20A SCD NCAPG TYMS PDGFD CRIP2 MANF SLC2A8 FOXM1 IMPA2 EPN3 THEM6 CYB561 TONSL PPP1R16A PROM2 HR FZD1 WWOX PRC1 PSRC1 CASR CENPA MXD3 PASK RAD54L FANCI ASF1B KIF22 GINS2 FAM83D NCAPD2 NPBWR1 SPC24 OIP5 TACC3 MCM5 CENPI SPC25 ARHGEF39 CENPM CCNF NCAPG2 SYT12 LRP8 CHAF1A SNCA DHFR IGFBP6 RAMP1 VCAN CLDN2 PCOLCE2 EPHB6 DDC PFN1 HNRNPM TUBA1B TMA7 PEBP1 THRA TPPP3 SMAD6 HPGD CHCHD2 LYZ CTSH ACAT2 RPN1 MYH10 COX8A NDUFS3 EIF5A ARL6IP4 MRPL20 PSMD3 IHH CETN2 NDUFB11 HADH NDUFB7 CCT3 AQP1 MPC2 VDAC3 FASN IVNS1ABP NDUFA4 ANAPC5 DBI PGRMC1 NDUFB10 TMEM147 MIEN1 CACYBP QPCTL TMEM213 OST4 ERI3 TM4SF4 HMGB3 ATP6V0E2 NDUFAB1 CUTA MIF AIFM1 POLD2 DCXR ATP6V0D1 PSMB3 DPP3 AHCY NHP2 LSM7 PIH1D1 PCNA HDAC1 POLR2E WDR54 NDUFA8 WDR83OS AHSA1 MFSD5 PTDSS1 POP5 GMNN HSPE1 HSPA1A SF3B5 MRPL11 C1ORF122 LDHB SDF2L1 SOSTDC1 VAV3 RUVBL2 NUDC SRSF2 ID1 MNS1 HSD17B7 CPNE1 SQLE ID2 CDH6 FANCG MCM6 DNAAF3 MVD TCTEX1D2 BCL2L12 SLIRP SNRNP40 FEN1 ANXA10 WDR90 ELOVL6 DERL3 TNFAIP8L1 GCAT MEDAG RARRES2 FGFR3 CYS1 CDKN2C LMAN2L PCSK9 TESC TRNP1 MCM4 MCM7 FAM149A SNRNP25 ALYREF RFC5 RFC2 IDH2 LRRC45 NEB LMNB2 LIG1 RHNO1 NCAPD3 TMEM237 CAPN8 MLEC KIAA0100 UCP2 NEFL HOGA1 GALM BRI3BP TM7SF2 COX5B UQCR11 HPDL CENPV FADS2 SCGN DPYSL3 CCDC34 HSPA1B PRDX2 PGK1 SKP2 ALG1 SDHA SNRPD3 TIMM21 IDI1 PARP1 CA12 TRIM54 GBA APMAP BDH1 SPP1 COPS6 CLN6 SLC25A10 ARMC6 DDX54 NUBP2 TRMU HSPB11 TBL3 FBXW9 SGK2 HMG20B ADI1 DGCR6L TSTA3 RABEP2 POLE4 LSS MVK AMDHD2 PRADC1 ALDH16A1 TELO2 TMEM129 KATNB1 UROD SMPD4 TCF25 TBCD FHOD1 SIVA1 FDPS HEXIM1 TCTN3 FDFT1 MCCC1 LRPAP1 CD320 CLPTM1L CHDH TEX15 ACACA VWA1 DTYMK LRWD1 PGP POLR2F IGFLR1 PRKDC SLC39A4 SCARA3 MTHFD1 KCNK2 CYP51A1 RANBP1 GCSH ICMT GJB1 F12 ACSS2 MCM3 ALDH1A2 PIN1 THOC3 POLD1 RECQL4 HNRNPAB IPO4 CENPO ENDOG TUSC2 CTDSPL ANXA9 BCKDHB FAM81A IMP3 RNASEH2C SLBP CHRNA5 GINS4 POLR2L BCL7C SRPRB RPGRIP1L C1ORF53 MFSD3 AIF1L CAMKMT IL17RB SFXN2 RBM14 CAPS COMMD4 GPS1 MANEAL KIF12 CSPG5 DHCR7 C7ORF50 OSBPL7 KCNMB4 UBE2E3 PXMP2 LAGE3 HS6ST1 PAGR1 MRPL41 NSDHL CHST7 PACSIN3 CENPT CTXN1 DPCD MAPKAPK3 SAMD1 PMVK PKDCC MMAB DSEL JMJD8 NRM HES6 PLEKHB1 EIF2B1 PCYT2 SLC22A18AS RERG TMEM141 TRAPPC2L DNLZ SLC25A1 ANAPC15 DECR2 MAOB STXBP6 AGFG2 NTHL1 MRPL3 GALNT10 EBP POLR3K ZNF580 GAMT THAP11 VPS26B GMPPB SYNGR1 MYL6B RIBC2 TSPAN12 TMX4 PIF1 RAB36 CHCHD6 ANKRD54 SDR39U1 ZFYVE21 PGAP3 ARHGEF19 TUB TMEM201 RPA1 C21ORF58 ELP6 MPV17L 500 genes up-regulated by SARS-CoV-2 in human lung cells from GSE147507 healthy v SARS-CoV-2 lung GSE147507 up IL1B FAM8A1 FKBP1A FGL2 CCL2 NMI TNF KPNB1 DDX58 LILRB2 YWHAZ IL1A CXCL10 IFITM3 TLR4 PDZD11 CXCL16 ARRB2 TPM4 IFITM1 YWHAE COL4A1 LYN HLA-B GNG5 CDHR5 FAR2 F5 RAB8A OAS1 SULT1B1 FCGR2A DMBT1 HLA-C STAT1 HLA-A IFITM2 B2M EIF2AK2 MGAM OASL USP15 ISG15 CD4 RPH3A SPI1 PLP2 MX1 CD55 BCL2A1 TPSB2 LCP1 SNTN CEACAM6 TMEM71 TNFSF10 PIGR SIX1 REPS2 MCTP2 FAM216B IGSF6 GCNT3 S100P GPX2 FDCSP METTL7B CXCL17 PNRC1 FREM2 TNS4 MARCKS STEAP4 APOBEC3A TET2 PRSS16 CCL8 LCN2 DHRS9 HESX1 GABRP KHSRP C1QC GSK3A TOR1B VASP PTK2B SF3B4 CD37 VKORC1L1 MYADM HCAR2 TOP2A MILR1 VSIG10L LMO2 C3AR1 LMNB1 PLBD1 KCNE1 GLRX IFI44 RNASE2 C1QB EPSTI1 NME1 BRCA2 PADI2 GLDN HP HPR CERS6 SPTLC2 CLEC12A CHI3L1 CST7 CCL4 CLC CAMP IL18RAP ABCC2 ACTB HPGDS MMP25 CYP24A1 LTF WNT7B TFAP2A ALPL MMP8 HLA-DRB5 MAP2K6 CTSC BCL3 FCN1 CBX4 ZNF385A SAA1 HCLS1 CD48 RSAD2 GPR65 OAS3 CD69 IDO1 IRF7 CFB GNG2 ZBP1 SLAMF7 LCP2 SIRPB1 GBP5 TNFSF14 MS4A7 TLR1 HELLS HCST GPR84 CHIT1 FCGR1A IFIT1 ARHGDIB CLEC4A RAC2 STAT4 TNIP3 PTPRC LY86 CLEC7A IGF2BP3 CTSS FCER1G S100A9 ENPP6 IFIT3 RTP4 SFT2D1 CYP7B1 OAS2 PHF11 XAF1 APOL6 CCR1 CXORF21 GBP4 CYBB IL1R2 GPR141 IL1RN IFIT2 HBB CLEC4E PLAC8 TMEM52B HERC6 CLEC4D IFIH1 TNFAIP6 STAT2 SFTPB PML CLDN2 CCL11 TREM1 NAMPT PARP9 SAMD9L GCH1 HSH2D CASP4 BASP1 RNF213 CCL19 C5AR1 CSTA UBE2L6 SP110 IRF2 FTH1 PSENEN PFN1 LY6E ATP6V0C CRYAB MYL12A IRF9 GBP3 DAZAP2 SFTPA1 SCGB1A1 SERPINE2 GABARAP IFI44L LITAF SERPINB9 SH3BGRL3 JUND CD74 TYROBP IFI30 CFL1 IL2RG ALOX5AP HCK NCF4 IVNS1ABP SAT1 NOP10 POLR2K GTF2B CD164 CNTN1 RBM11 COL9A2 C1ORF194 SAMSN1 ZC3H12A LST1 ASCL2 SIGLEC7 BPI TRIM22 CR1 S100A12 CYTIP PGLYRP1 DCUN1D3 LRRK2 NTNG2 SEZ6L2 ADRA2A ANP32A PSMA4 MPV17 CHMP5 S100A11 SF3A2 PSME3 DYNLT1 CKLF SNX10 HSPA1A MXD1 PDE4B HAMP MNS1 MSMO1 C15ORF48 ANXA2R CTF1 P2RY14 P2RY13 TNFSF8 S100A8 CASP1 CSF3R GCA TRIM21 ZC3HAV1 SELL TRIM5 TDRD7 PCGF5 POU2AF1 BCL11A WAS CTSE RHOH STAP1 OLR1 FPR1 CD38 PDGFRL PTMS ALDH3A1 HS3ST3A1 BIN2 CXCL11 ZMYND12 RP2 IFI6 LY96 RAB11B MNDA CHRAC1 LAMP3 DDX60 RNF19B LGALS9 TNFSF13B XRN1 MX2 IFIT5 HERC5 DDX60L SAMD9 GBP1 PSTPIP2 UCP2 CEACAM1 KLHDC7B CSTB ARL5B PATL1 NAPA SP140L C1S SOD2 VNN2 HLA-DPA1 TRIM38 RABGAP1L PIK3AP1 CFLAR RNF149 RAB8B SERPINA1 SERF2 SRGN FCGR3B GPSM3 CSF2RB SERP1 CDA CD53 GNLY PLEK LPAR6 EVI2B AIM2 FCGR1B SPRR2E HBA2 APBB1IP NCOA7 TP73 VNN3 ZDHHC19 AMDHD1 CA1 CORIN FCAR CDH2 CCL3 GATA1 CCL7 TIMM23 USB1 CLECL1 PILRA SIGLEC5 LILRB3 LILRA6 LILRA5 ARHGAP9 FGR STX11 NCF2 GK FCGR3A SIGLEC14 AQP9 DOK3 CARD16 BCL2L14 CASP5 HBA1 TRPA1 CA12 PELI1 SP140 PI4K2B VSIG1 CAPZA1 C4ORF3 CCL18 BLOC1S1 FFAR2 KCNJ2 RBP4 SLC39A8 MROH8 CMC2 TREML4 NME8 CLEC1A TLE4 MCTS1 TAOK3 WIPF1 MIER1 POPDC3 CPLX2 IQGAP1 G6PD PIM2 F8A1 CYP19A1 DBNDD1 GMFG ACSL1 RGL4 BCL6 CARD17 TFEC ST20 HCAR3 NEXN DAPP1 CCDC114 C20ORF203 YPEL3 AGMO LILRA1 OLIG1 STK24 PROK2 DNAH7 TENM1 EIF1B CHI3L2 NBN ALPK1 ANKRD22 LBP RGS18 HNRNPC CACNA1A ATP7B STRN4 CYSTM1 SLC9B2 KCNH7 TPP1 JAK3 FHL3 MAP3K13 SYN1 MDH1B GAPT CCDC71L NFKBID HSPB6 TMEM154 RTN3 CEACAM3 KLK10 PPDPF DNAAF1 SMAP2 PSEN1 SFTPA2 SLC26A8 CDR1 FLOT1 CISD2 PAK1 SIAH2 C8ORF82 500 genes down-regulated by SARS-CoV-2 in human lung cells from GSE147507 healthy v SARS-CoV-2 lung GSE147507 down GAK CANT1 BCL2L1 EEF1A1 MPHOSPH10 ZC3H7A EGR1 FBXW5 SUN2 BCAR1 DDX5 TUBGCP2 MYO1D BAIAP2L1 GOLGA3 UBXN1 TMBIM1 RASA3 CUL1 NDRG1 TUBB4B MRPS2 BAG3 TUBA1A HMOX1 DNMT1 EIF4E2 TUBA1C TUBA4A SFN MEPCE HERPUD1 PES1 PPIG MOB2 HSPA8 USP7 ZBTB44 SCYL1 SGTA PLEKHO1 BAP1 BCL2L2 NEBL RPL41 NR4A2 RPS3A SLC25A4 RPSA ABLIM1 MEIS1 STARD10 CCND1 TMEM109 CD2BP2 PIEZO1 USF1 MICAL1 ATG4B DPP7 AKAP1 XAB2 ZC3H7B LDB1 SEC24C USP19 DNAJB2 ZDHHC7 QSOX1 BSDC1 EIF3B PLEKHO2 ZSWIM8 NDST1 SIN3B APH1A SMAD7 ITPKB PPP6R2 DDB1 ADAM15 KIAA0930 ARHGAP29 ACVRL1 MAFG CCT8 DOCK1 SMTN ADAMTS2 GRB10 HEXB UNC13B SH3PXD2B PRELID1 SEMA4C SLC25A29 PBXIP1 MYC GADD45G B4GALT3 KLF13 TRAK2 TGFBR2 PIK3IP1 GADD45B TRAK1 STAT5A PSMD6 SEMA3F ALS2CL ITPR3 PYGO2 TFIP11 WDR37 FZD4 FIBP HDAC3 CTR9 RGS3 UPP1 EDC4 C2CD2 PHC2 CYP1A1 PDE2A RPS28 TNS1 IER2 FOS SGK1 EIF3G DUSP1 ID3 EGFL7 GATA2 PXDC1 JUN CLDN5 RPL3 RPLP0 POLDIP3 SFTPC MAT2A CRIP1 LUC7L3 RPS5 NR1D2 VPS28 PPP1CA C1QBP NDUFS6 TCF21 HCFC1R1 SH3PXD2A EFNB1 CAMTA2 KLHDC3 HEXA RAPGEF3 ERRFI1 LBH STK38 SERPINB6 SELENBP1 SLC25A3 TPRG1L CCNL2 CTDSP2 FAM160B2 GUK1 S100A13 MYZAP CCDC85B RRAD AKAP17A SLC25A25 STARD9 MYCT1 F2RL3 TCERG1 GJA4 ROBO4 STC1 SERTAD1 MAFF FOSB ZNF263 CIB1 TMEM208 CKB NRBP1 ASL C12ORF57 EBNA1BP2 BCOR TSPAN4 PSMC1 ZNF593 MGLL NELFE TUBB6 GNL2 SF3B5 SPSB3 DNAJB4 ODC1 EIF2B5 MFAP1 MLH1 RANGAP1 PAN2 ARRDC2 ITPKC BLCAP GALNT18 RND1 DEXI MUL1 NUDCD3 PPP3R1 RNF31 DLL1 MEDAG DLST INPP1 RARRES2 GOLGA8A PER1 FAM13B MCM7 AMFR DNAJC7 KIF3B KIAA0100 ATRX EIF2B4 ST6GALNAC6 SLC25A36 RALBP1 ARPC1B ENO2 PDXK THAP2 RALGDS GRPEL2 NR4A1 TMEM255B CSPG4 MCAM COL12A1 GNA12 GET4 ANAPC11 EXOSC7 TXLNA CTCF CDK9 BCR KDM1A PRMT1 PGF NFATC2 MMP14 PRKAB1 GRSF1 SPRYD3 SEPHS1 AIP CD82 PSMC5 DDX56 MAPKAPK2 SAE1 PSMC3 TNFAIP1 CYTH1 ROBO3 WIPI1 FAM32A SLC35A4 ZNF330 CHMP1A AHNAK CDC42BPB CDC37 CIRBP URGCP EHMT1 MPHOSPH8 ANKZF1 FAM118A RASSF1 ARHGAP10 PTCD3 DHX29 ZMYM2 DLL4 HMGXB3 ACTR1B MEF2D ULK3 PLEKHM1 ITPA ENG PODXL PHLDB1 MLXIP THOC6 ASB1 DDX39A MFNG MADD TRPC4AP HDAC7 ZFAND2B PARVB TANC1 FOXK2 RRP1 INPP5A ARHGEF7 E2F4 ZSCAN18 SSH2 PLXND1 PYCR2 PMM2 NOP56 RNMT PRDM2 PPP1R14B SKIV2L RRP12 ATP6V0A1 KCTD20 ATP6V0A2 CYC1 PXDN DCAF5 ENTPD6 CRY2 MYO9B CC2D1B RAPGEF1 SERTAD3 EPC1 GGA2 BRD9 ILVBL MAP4 LUZP1 MDC1 NFATC4 TAF1 HARS2 ELK3 SNAI1 SLC38A5 RXRB TTC7A METTL3 DAPK3 S1PR2 VPS13D MOAP1 SLC39A7 KCTD10 PCDH12 RHBDF1 KANK2 SRCAP CCM2 AMOTL1 AGAP3 ACP2 TSR1 TIMM13 FARP1 PPP1R13B FBXO31 TSPYL2 INPP5K LETM1 HBP1 UROD CHFR CTPS1 ADCY6 DKK3 VPS54 SMPD4 NCAPH2 RBM6 MICAL3 SSH1 DST PELO STARD3 ADCY4 NOC2L TCF25 DTX4 GNL1 MFN2 TBC1D9 OSBPL5 ZNF160 UBE2J2 SLC9A1 SUN1 PDGFRB RAF1 PLEKHM2 NDUFA11 PLXNA2 SPRED1 ABR XPC NOL8 NISCH LRRFIP1 ABLIM3 KAT5 VSIG2 UTP6 RRP7A SASH1 URB1 FLNC LCN10 TBCD LRRC32 FHOD1 SGSM3 SLC25A44 GLT8D1 USP22 EDC3 VPS37B GAS6 TTL PCID2 SNX11 LZTR1 BAALC NES MBIP LMBR1L TSSC4 CTTN ITPR1 SIVA1 UCK2 NASP ARHGEF15 DOCK6 TXNDC11 DDX42 PRKY GMPPA PPP1R12A PPP1R16B AFG3L2 SREK1 RSAD1 LRRC47 SGSM2 PSMD2 NAP1L4 HIPK2 FDPS GUCD1 FAM219B ZNF451 SPHK1 PCDH1 RBFOX2 LRIG1 RPS6KA2 WDR74 WBP1L ATP8B2 FAM214B MAF1 IFT43 PEX5 ERCC1 ARFRP1 SPG7 CCDC130 FXYD6 XRCC6 DCHS1 NAB2 ARAP3 TPD52L2 REV3L SAFB2 TBRG4 DDX47 Top 500 upregulated genes in mouse D1 cardiomyocytes with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113 PTPN14 CEP350 RSRC2 SYVN1 HSPA5 XPO6 APC EGR1 SQSTM1 ATP6V1A MAST4 EP300 NEDD9 ZBTB7B ZNF274 KLF6 CLCN6 TLE3 RYBP NFKB1 BRD2 SERPINE1 PDE4D HERPUD1 FERMT3 SLC44A2 EDEM1 CHD1 ATXN2 NR3C1 VLDLR VPS13B ZNF532 TRPS1 HES1 DUSP16 EXT1 ZEB2 LRIG3 GATAD2B NFIB PNRC1 RICTOR FNIP2 ZNF827 TET2 SATB1 RND3 ANKRD33B PRDM1 OTUD7B SETBP1 ZNF507 SIX4 ABCA1 KCNQ1OT1 ZNF462 ARID5B THBS1 SLC3A2 SMAD7 RARA CD101 ZBTB43 LDLR DDIT4 STARD13 MAFG UAP1L1 SPRY2 PPARGC1B RASGEF1B IKZF2 TNRC6C PTCH1 CRY1 NUAK1 LINS1 MYC NOTCH1 KLF10 KLF11 ZFP36L2 GADD45B PIK3CA EDN1 ASB7 FOXO1 CSNK1G1 PLEKHH3 GTF2IRD1 APPBP2 FAM83G ZNF217 PRICKLE1 FGF10 ATF3 DACT1 HERC2 ZFPM2 SOX6 BCL3 FOSL2 PHF12 KMT2B CREBBP NUAK2 CASZ1 SETD1B PREX1 ZNF442 CYP26B1 SOCS3 NFKBIE ADM PIM1 LIPG INHBA SLC39A14 DBP UCP3 ZFP36 CYR61 IER2 FOS SNRK DUSP1 TXNIP NFKBIA JUNB RAPGEF2 JUN CTGF VEGFA AMMECR1L EFEMP1 NR1D2 ARRDC3 PIM3 CCNL1 FNDC3B VWF YTHDC1 SLC38A2 GEM MYO18B CREB5 RRAD ZC3H12A DDIT3 DUSP8 SLC25A25 LIN28A NR4A3 RAB30 PPP1R15A CSF1 DCUN1D3 ZNF432 VCPKMT TNFAIP3 CIART ZNF292 PLA2G4C BCORL1 AMOTL2 BRD1 DUSP6 PPP1R15B KLHL15 FLRT3 IRS2 TIPARP YOD1 CSRNP1 ZSWIM6 CHAC1 BHLHE40 MAFF NFKBIZ SERTAD2 ZNFX1 KANSL1 SH2B3 PPRC1 DHRS2 RLF GNA13 MXD1 ZNF317 DNAJB4 USPL1 INTS6 GPBP1 DUSP10 PDE4B PAPD5 ZNRF3 INSIG1 SETD2 RRAGC CREBRF HMGCR ID2 IP6K3 HIVEP2 SFSWAP ZBTB2 REL MAP3K14 AVIL ETV6 MORC3 AJUBA IRX1 PRKD2 ST8SIA5 CASS4 PRPF38B LIN28B PER1 HIST1H2BG ARID4A XRN1 TAF3 PDPK1 SECISBP2L NIPBL DNAJC3 FNIP1 PPP1R10 RFX7 ETS2 PLK2 RFPL3S AFF4 RELB BAZ1A DYRK1A ST6GAL1 SKIDA1 PDE7A RAD52 ATF7IP FRY BACH2 CLK1 JARID2 ERBB4 NR4A1 TNFRSF10D LINC00641 NR1D1 ETV3 C7ORF61 CCDC116 CDC14A ELFN1 POLR2H UBA2 STX11 CREB1 SOX5 EEA1 TBX2 SPEN SPRY1 XBP1 NFATC2 NFKB2 FAF2 CYLD SMURF1 UVRAG ZNF44 CITED2 B3GNT2 FAM193B USP36 PHC3 FLCN HELZ ZNF14 EPHA2 ZBTB10 RBBP6 PTP4A1 MEF2D ARID1B PLK3 CHST3 TET3 MIER1 BCL6 KCNH7 TANC1 CRY2 EPC1 TBC1D9 SPRED1 SREK1 ATP8B2 ANKRD17 RIPK4 UBE2Q1 GHR GRK5 GATA4 PER2 HDAC4 LMTK2 RREB1 CHD8 E2F3 USP9X FOXP1 KMT2A PIAS4 KMT2C ZBTB18 JMJD1C SHROOM3 RUNX1T1 CCNG2 ZBTB21 CHD2 SPRED2 EIF2AK3 ZFYVE1 MAP1A FBXW7 UBR5 UBR4 SLC19A2 PPM1D FGD4 RC3H1 ZNF543 ZNF202 ZNF627 TOGARAM1 RSBN1L ZNF398 HYPK SEC24A TRIP11 CRAMP1 UBXN7 SETX SLC22A5 TGIF1 LCAT RFX3 MAP3K2 TRAF4 CBLB GPAT3 SOX4 UTP18 PVT1 LATS1 LATS2 MAP3K9 VIRMA ZNF746 SUSD6 DSE XIRP1 SYNJ1 USP42 NOP2 SCAF4 TBC1D22B THAP1 RBM33 MED26 SIK3 ZNF335 MGA GAPVD1 ZBTB11 IP6K1 RNF111 DCP1A MTMR3 ITSN2 INO80 BRPF1 MLLT10 ZFX KDM2A ELMSAN1 DLC1 SKIL CLK4 HIVEP1 MIER3 REV3L TENM3 ACVR1 ZNF608 PHIP CHST11 IFRD1 FRS2 ZMIZ1 PDE10A PHLPP2 MED13 DIDO1 TRAPPC8 CAMSAP2 RBM15 KAT6A VEZF1 CDK13 CCDC93 TNRC6A PPP4R3A CNST TRIO KMT2E LCOR OSER1 PCF11 SETD1A FOXN2 ADAMTSL4-AS1 ZBTB7A EMSY RAI1 BICRA CPEB3 ARID4B CPEB4 FRYL PRAG1 ZNF264 SIDT2 HIST1H3E FAM126B CEP85L CHD9 ZNF79 IKZF5 USP37 INO80D CARD9 SNX16 RLIM IRF2BP2 GZF1 ZNF143 SLC12A4 RSBN1 ARHGAP26 FAM193A CNNM2 SNX30 KDM7A FBXO28 PHLPP1 SLMAP CHD7 PPP3CC CLK2 CSPP1 IPMK DENND1B MMRN1 SYNDIG1L CDKL5 SHROOM2 NCOA6 ZNF675 ZNF844 MYH3 NOL4L ZNF101 DCAF4L1 IPPK BAHD1 RNU6-322P FAM183BP KAZN AL513534.1 GPR19 AFF3 RPL23AP15 ZSCAN12P1 ZCCHC8 GPATCH2 LRCH2 AC015813.1 WNK3 ADIRF-AS1 ATXN7L2 AC021078.1 ZNF521 TMEM200C Top 500 downregulated genes in mouse D1 cardiomyocytes with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/9ZPBPzpL9 GOT1 UBB FOXRED2 UBL5 DCAKD TIMM8B EEF1A1 FKBP1A SH3BGR VCAM1 GHITM NPTN ETFA PRKACA PPP2R1A KPNA2 LMAN2 SLC30A9 TUBB4B LAP3 AP2M1 HSP90AA1 LARP7 CTNNB1 PSMD4 HEPH PMPCA ING4 NUTF2 MFGE8 BRCA1 PLD3 C11ORF74 HSBP1 PHB NEDD8 AAMP NDUFAF1 TKFC UBQLN2 HS6ST2 FBXO9 TSR2 MDH1 ABHD11 SRR ADH5 UFC1 FAHD1 PTTG1IP ATPAF1 NDUFV1 ENY2 FECH CHEK2 NDUFA10 DANCR PPP1R14C UQCR10 ARL3 FREM2 KLHDC9 TSTD1 NDRG2 ACOT13 CHCHD10 PRNP BANF1 PRPS1 STMN1 LGALS3BP UQCRC1 GANAB NRP2 CPVL DDB1 AK2 ZWINT TK1 LMNB1 CCNB2 NREP SLC16A1 NEK2 SPAG5 MCM2 MRPL15 KIF14 FH HADHB COMMD9 PRDX1 SAPCD2 ROGDI G6PC3 ANLN CDCA3 ACO2 TRIP13 PRDX3 TPI1 KIF20A PSMB7 GSTM2 YPEL1 PBXIP1 NAP1L2 CKS1B APLP2 CYCS WLS ODAM WNT2 ARHGAP1 HNRNPH2 SLC8A1 MLLT11 TRIOBP SMC2 UBE2T ASF1B GINS2 GATM NUSAP1 MCM5 IFIT1 SPC25 H2AFX HMGB2 TNNT2 SRL ITGB1BP2 CKMT2 MYL4 SNCA DHFR TMEM143 TNNI1 ACTC1 PSME1 CLIC4 PSENEN HNRNPM TUBA1B ATP5G3 UNC45B PEBP1 COX17 ATP5J EIF2S3 DAZAP2 RBBP7 EIF3I MDH2 SNRPD2 PSMB6 MRPL20 PSMB5 NDUFS6 MORF4L1 QDPR PAIP2 ATP5H EID1 NDUFB3 PTGR1 SRP14 OAZ1 NDUFA2 PRMT2 PSAP KLHDC3 NDUFA1 NDUFA6 VDAC3 GM2A NDUFA4 NOP10 MARCKSL1 ANAPC5 PPIC IGFBP5 PGRMC1 NDUFB10 CACYBP DEK TAF11 FBXL22 TMEM14B ASB2 COL9A1 HMGN5 GPX3 UBE2L3 ANP32A OST4 NDUFS2 ERI3 ATRAID HMGB3 BABAM1 RRM1 MSRB2 ATP6V0E2 ARL6IP5 AIFM1 POLD2 IDH3B PTTG1 SLC25A11 PARK7 RPA2 PSMB3 DPP3 AHCY GSS PCNA THYN1 NIF3L1 MSH2 NDUFA8 PAM SUSD5 PIGP MRPL16 HTATSF1 ACTR10 SKP1 HMGN3 LDOC1 NUP107 AKR1B1 ERH TMEM50A CUEDC2 PDHB CHTF8 SF3B5 LDHB RNF20 GFM2 APOBEC3C SRI BLCAP MTFR1L MCM6 NIPSNAP3A SLIRP FEN1 ATF6B ADPRHL1 RXRG ATP1A3 CTSV MCM4 ABAT MED29 BBS2 SNRNP25 RFC2 IDH2 HNRNPA2B1 MLEC GLG1 KCTD12 GALNT11 TCTA PCDHB5 FAM210B MDK SOD2 GALM TM7SF2 NDUFB4 UQCR11 MYL9 SRSF5 PDK1 SPRYD4 OLFML3 SLC30A3 DPYSL3 ATP1B2 HRC CORIN PRDX2 PGK1 PEF1 VPS45 SDHA TRAPPC1 VPS29 OGG1 ACTR1A GTF2H5 USB1 RMDN1 BSG PARP1 STX8 TXN2 USP5 PPP5C RAB5B FKBP3 SAE1 PEX19 HAGH PSMC3 RNF181 PPCS NTAN1 RTFDC1 ASTN2 TPM1 CALCOCO1 CMAS COPS6 C4ORF3 CIRBP ACAT1 ACAA2 COA3 CSRP2 GGCT PARM1 TRMT2B TTLL1 DHRS4-AS1 MRPL33 HLTF SMS CPS1 ADI1 MATN2 TRAPPC6A PRADC1 SFRP5 SLC39A7 UROD DKK3 CTTN NASP RSAD1 ERCC1 FXYD6 ATP6V1G2 MCCC1 LRPAP1 KCNIP2 ELAC2 DTYMK FIG4 PRKDC NCAM1 CAMK2A PCYT1B PARP4 CPT2 GSTM4 MCM3 PPP2R5D NDN LSM4 HNRNPAB FBXW2 HSPB7 SELENOW TPD52L2 TMOD1 ECHS1 SLC25A20 ETFDH PDHA1 PNKD TPGS2 BCKDHB TIMMDC1 RMI2 GINS4 DARS2 ALDH7A1 GPC4 MAGED2 LRRN3 DPCD PMVK EIF2B1 RPA1 ELP6 ANXA6 CARHSP1 LANCL1 CPE COL22A1 FOXRED1 RTL8C CCDC167 DMAC1 DCAF11 IDH3G ATP5G1 PFKP ATP5A1 C14ORF2 HSDL2 LSM3 FAM104B ZCCHC17 BEX3 HIRIP3 SMIM30 FANCL SPA17 CD99L2 HNRNPR VWA5A PCCB ECI2 ACAD8 COL2A1 TRIM45 NID2 MPI AGPAT1 NIPSNAP2 TRH PGM5 CLYBL TSFM OGFOD3 AAMDC TAF9B TMEM69 COMMD7 C15ORF41 ATP2B4 CTBP1-AS2 ATP5O IMMT CHCHD7 ZDHHC16 DYNC1I2 ZFAND6 JPT2 TMEM106C ATP1A2 NAP1L3 MIR133A1HG SMPX EFNB3 LINC00648 AP002360.2 NAV2-AS2 AP001107.5 GJA5 PPP1R1A LINC00881 SMYD1 PKIA AC018521.5 LRRC10 IFI27L1 NCBP2 TMEM161B-AS1 DLD SLC22A17 GADL1 ARV1 CSTF2 COG4 CEP70 NUBPL RCC1L COA1 SMUG1 STUM AGBL5 EEF1A1P11 AC117402.1 AL355338.1 AC025183.1 LINC00890 MRE11 MIR99AHG FGF14-AS2 PPIP5K1 CASC10 MOXD1 ATXN7L3B NBDY PNMA8A DMAC2 AC100810.1 2-SEP ADAL SNU13 PNPLA4 RASSF8-AS1 PSMG3-AS1 Top 500 upregulated genes in mouse D2 cardiomyocytes with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/doSiYBX2h F2RL1 PTPN14 RSRC2 GDF15 EGR1 SQSTM1 LOX STX3 MME EP300 NPC1L1 HLA-B NEDD9 BRAF BAG3 KLF6 CLCN6 MEP1B TLE3 RYBP HMOX1 BRD2 SERPINE1 FRMD6 FLT1 SNIP1 TMEM39B FN1 CRK FBN1 MEPCE HERPUD1 VPS11 TGFB1 YWHAH MAP3K1 NCAN EDEM1 CHD1 LRRC1 FBXL3 MYO10 KRT18 KLF5 RGS2 HES1 DUSP16 EXT1 ZEB2 MT-RNR1 PARD6B SYTL2 LRIG3 GATAD2B RNF152 OSMR PNRC1 CCDC80 MT-RNR2 GADD45A RND3 PRDM1 SETBP1 SIX4 CEP170 ARID5B CCND1 SRRT TAGLN2 THBS1 SLC3A2 HBEGF TGFBI SMAD7 RARA RHOB NET1 DDIT4 ELL2 MAFB ITGA1 SPRY2 NECTIN2 CDKN2B RASGEF1B ARL4C PTCH1 TOPORS CRY1 KRTAP5-AS1 IGFBP3 NUAK1 LINS1 MYC TUFT1 NOTCH1 GADD45G KLF10 SLC2A3 COL1A1 KLF11 ZFP36L2 GADD45B BMP4 BDNF EDN1 MYCL FOXO1 USP32 FAM83G SLC7A5 ZNF217 RHOU COL1A2 TMSB4X AXIN2 DKK1 FRZB ATF3 MSX2 EFNB2 FZD7 TFE3 FOSL2 CREBBP NUAK2 SELPLG MTFR2 GPR176 COL3A1 SOCS3 NFKBIE ADM NFIL3 PIM1 INHBA BASP1 PCDH10 MAMDC2 ETS1 KLF4 ZFP36 LASP1 CYR61 IER2 EPAS1 FOS ACTG1 SGK1 DUSP1 ICAM1 NFKBIA SPARC CDC42EP1 UBL3 JUNB RAPGEF2 PXDC1 JUN CTGF PDGFRA ADAMTS15 EFEMP1 SERPINE2 NR1D2 TAGLN SERPINB9 DDR2 DDX3X EPC2 FHL1 ATF4 ERRFI1 CCNL1 DNAJB1 FNDC3B ANXA1 C1ORF198 PHLDA1 SRSF3 SAT1 YTHDC1 COL6A3 SLC38A2 DLK1 CREB5 ZC3H12A DDIT3 SLC25A25 EGR2 NR4A3 PPP1R15A CSF1 SYNGAP1 DCUN1D3 KBTBD8 TNFAIP3 CIART CCDC89 PLA2G4C FILIP1L CDKN2AIP AMOTL2 LIF KLHL15 FLRT3 IRS2 IER5L IER5 CSRNP1 BAMBI ZSWIM6 BHLHE40 MAFF NFKBIZ SERTAD2 ZNFX1 KANSL1 IL11 FOSB SH2B3 MSL2 PAN3 PPP1R18 GJA1 HSPA2 ARG2 SIRT1 RLF MXD1 ZNF317 DNAJB4 TOB2 INTS6 GPBP1 TAF4B GRB7 DUSP10 KIAA1683 YTHDF1 NUFIP2 ANKRD1 ID1 EFNA1 MN1 SETD2 RRAGC CREBRF FAM46B ID2 IP6K3 HIVEP2 DIAPH3 CEMIP RND1 COL11A1 CENPL ZBTB2 REL ABL2 NNMT ASNS FAM46A RASD1 BTLA OLR1 RASL11A PRKD2 PRPF38B SYT16 PER1 BMP10 SLC20A1 TFPI2 MIR22HG CRKL SMURF2 CRIM1 YTHDF3 ATAD5 PPP1R10 RSF1 LIMA1 PLK2 AFF4 RELB BAZ1A NPY1R CDKN1B DYRK1A KANSL1L MEX3B CDC42EP2 BACH2 CLK1 BACH1 PAPPA NR4A1 LOXL2 IGF2 COL12A1 TNFRSF10D NR1D1 SPRY4 ETV3 PRKG1 CDC14A PUM1 HSPA1B RAD21 STX11 SPEN CXCR4 MMP14 PELI1 NFKB2 FAF2 ELL NUP153 SMURF1 UVRAG ZNF34 ATG3 AKIRIN2 FLCN HELZ EPHA2 ZBTB10 AHCTF1 RBBP6 USP53 PTP4A1 GREM1 PLK3 THOC6 TET3 DDX39A TLE4 MIER1 IQGAP1 BCL6 ATP7B EPC1 AMOTL1 TSPYL2 PELO TBC1D9 PDGFRB SPRED1 NAB2 MEX3C HEXIM1 ITGA3 NFE2L2 CPA4 PER2 KMT2A ID4 KMT2C ZBTB18 JMJD1C ASXL1 ZBTB21 CHD2 WISP1 SPRED2 MCOLN1 EIF2AK3 ATG2B HIST1H2BJ RAB33B CRTC2 TFPI FBXW7 CXCR1 LUM TSC1 PPM1D SMCR8 VCPIP1 PTBP1 SEC24A PEAR1 TGIF1 COL5A1 LCAT RFX3 SYNPO TRAF4 GPAT3 UGCG CREB3L1 SOX4 LATS1 TEF LATS2 SPSB1 FLNB EHD2 CELSR3 NOP2 DDX20 ZC3H4 SCAF4 YY1AP1 THAP1 PIP5K1A SIK3 ZNF335 ZBTB11 IP6K1 TIAM2 RNF111 MTMR3 INO80 BRPF1 AEN MED13L ZFX KDM2A DLC1 SKIL FSTL3 CLK4 HIVEP1 DIP2B DSC3 FAM43A PHIP APBB2 GFRA1 IFRD1 PHLPP2 TRAPPC8 CAMSAP2 RBM15 KAT6A LEMD3 USP38 CDR2 PDZD8 TNRC6A CAVIN1 KMT2E OSER1 CWC25 SETD1A FOXN2 ARID4B PRAG1 TRPC4 SWAP70 HIST1H3E ZNF281 CEP85L SNX16 IRF2BP2 CDK5R1 ZNF143 PPP4R2 SVEP1 DUSP14 FAM193A CNNM2 PHLPP1 CHD7 CNTD2 CSPP1 LSMEM1 TIGD3 INA SHROOM2 TUBB2B GPR37 ZNF619 P3H2 PCDH18 LRRC37B MAML2 GPR19 ZCCHC8 WASHC2A LRRC37A15P AC141586.1 AC025594.2 KIRREL1 AC234775.1 PHF8 AL365203.3 MEST AC021092.1 AC017104.2 WASHC2C RSPO2 GDF7 EPOP GDF6 ERVH48-1 KRT8P36 AC084880.1 Top 500 downregulated genes in mouse D2 cardiomyocytes with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/doSiYBX2h GOT1 TIMM8B SH3BGR VCAM1 CTDSP1 PFAS ACADM NPC2 IL17RD HEATR3 PDZD11 DDX1 SLC30A9 COQ8B POLA1 BZW2 HEPH ING4 MRPS25 ERBB2 NDUFB9 PMPCB DHRS11 PRKAR2B PTGES2 EVL DPH5 MDH1 SCRN3 TMED4 SCP2 FAHD1 PEX1 ATPAF1 FN3K FECH NDUFA10 H2AFY2 PPP1R14C NEBL FREM2 SLC25A4 NDRG2 SGPP2 ACOT13 SLC25A23 CHCHD10 TTC14 PYGB RFX5 PLCB2 CPVL NDUFB5 PLBD1 NREP PSEN2 MRPL15 NUDT16 HADHB MPND ROGDI TP53I3 GRHPR CORO6 PDGFD MTERF2 MLF1 PBXIP1 PLCXD3 CHURC1 COL14A1 FGF12 ODAM CTNNBIP1 FIBP SLC8A1 SORCS1 UBE2Q2 HACD1 MYH4 TNNT2 MYH6 SRL FABP3 ITGB1BP2 MYBPC3 CSRP3 PGAM2 MB CKMT2 MYL4 MYL7 UNG TNNI1 MYH7 ACTC1 TNNC1 HMGN1 ATP5G3 UNC45B ATP5J NPNT COX7A2L MAT2A MDH2 EIF3K PRRG3 COX8A MRPL20 COX4I1 ATP5H NDUFB3 RHOQ TMEM50B NDUFA5 NDUFA2 PRMT2 KLHDC3 TEX261 COX6B1 NDUFA1 LBH PSKH1 VDAC3 GM2A NDUFA4 CD36 TRUB2 IGFBP5 PMP22 ATP5J2 BEX4 ATP5C1 NDUFB10 COX14 MYZAP FBXO40 LDB3 FBXL22 LIX1 BMP5 ASB2 KLHL41 LINC00982 FUS CITED4 TMEM120B MIR210HG MAPRE3 NDUFS2 GYS1 MSRB2 ATP6V0E2 RBPMS2 EPDR1 SLC29A1 STK39 UQCRQ THYN1 MSH2 NDUFA8 SLC25A5 PIGP MRPL16 AHSA1 FAM96A ATP5L ACTR10 HMGN3 ADSL MRPL1 PFKM HSPE1 EXTL2 CUEDC2 PDHB LDHB RNF20 TMEM55A C15ORF52 C10ORF71 NIPSNAP3A APOBEC2 MYL3 TSPAN32 ADPRHL1 RXRG WDR86 C19ORF25 ISOC2 ARL15 CTSV APCDD1 MCM4 NAA40 ABAT C22ORF39 DIRAS3 ACP6 PLEKHA6 IDH2 CDCA7L IMPACT STARD4 PPIL1 MRPS11 ZNF302 DIS3L PCDHB5 BBS4 SDAD1 FAM210B SOD2 MVB12A SCAMP1-AS1 GALM DYSF RASSF4 PDK1 LMOD1 PPFIA4 FHL2 SAMD10 MLIP SLC30A3 RNF144A JPH2 HRC PYGM SCUBE3 CPNE4 KLHL14 CLCNKB CORIN PRDX2 VPS45 COQ6 AASDHPPT COQ9 TADA2A GTF2H5 RMDN1 HPS1 QARS TMEM167A NDUFB1 TNFAIP8 PRPF6 COX20 GSTK1 FAM32A SUCLG1 HPF1 NNT ASTN2 TPM1 CALCOCO1 C4ORF3 CIRBP ACAT1 CHMP3 COMMD6 PARM1 TRMT2B TTLL1 LRRC20 THEM4 HLTF IFT81 CPS1 BCAT2 MATN2 PRADC1 ARFGAP2 TMEM129 MOAP1 UROD NES NAP1L4 FAM219B FXYD6 TDGF1 WASHC5 PLN TRIM9 MTUS1 KCNIP2 SIRT3 TSPEAR PLEKHH1 SH3GLB2 ABCA8 PTP4A3 BIK STX17 FSD2 IVD EEF2K KCNJ8 PRKN ENOSF1 HRH2 CAMK2A PCYT1B ANGPT1 PRMT6 MCM3 POLDIP2 ANAPC4 CDCA4 LPAR3 FBXW2 HSPB7 RCSD1 MAPK4 TMEM14C SELENOW TMOD1 PDHA1 ASPH CEBPZOS FAM81A ANAPC16 FITM2 SH3RF2 VWDE LRRN3 SYTL3 RPGRIP1L PACSIN3 MAPKAPK3 MMAB GAMT TMX4 ZFYVE21 PGAP3 ANXA6 CARHSP1 RBFA DZIP3 LANCL1 CPE PPP1R3C FRMD5 TMEM67 COL22A1 GPD1L PDK2 RTL8C TMED1 DMAC1 STK36 APEH ATP5G1 PFKP RFXANK ATP5A1 HSDL2 GABPB1-AS1 CBY1 AC106820.4 BORCS8 CCDC69 RBBP9 SMIM30 FANCL HIGD1A IFT80 CD99L2 OXCT1 ARHGEF9 DBNL VWA5A MLYCD BPHL ACAD8 COL2A1 STRIP2 PHKB CAP2 MPI REXO5 ST3GAL6 DENR NIPSNAP2 TRH NECAB3 PGM5 CACFD1 SFXN4 MTURN TSPAN2 FASTKD1 SMIM19 TXNDC15 COMMD7 INAFM2 C15ORF41 TPCN2 SRP14-AS1 UROS WDR61 COPS7A CHCHD7 TMEM106C MTUS2 LINC01278 MIR133A1HG EFNB3 FITM1 TECRL SPSB4 KLHL3 SMTNL2 GJA5 HEY2 COA5 PPP1R1A LINC00881 PHACTR1 AC107068.2 VSTM2L SMYD1 PKIA HAND2-AS1 PTGES3L LRRC10 PPP1R12B RNF207 LYRM7 DCTN1 TCEAL4 EXOC7 POLR2I DNAJC30 DYRK4 DLD SPIN3 MTMR4 ENGASE AGL TTC19 SLC18B1 TCEA3 TARBP1 N6AMT1 C3ORF18 RPP25L PCDHAC2 RIMKLA TENM4 GADL1 TMEM223 ARV1 C2ORF68 MYLK3 MAPKBP1 NUBPL PPP2R2B COA1 STUM OGDHL FREM1 DIS3L2 LINC00890 CASC10 MOXD1 ADAL WAC-AS1 5-SEP MYADML2 CYB5D2 DUSP27 GPRASP2 AL513318.2 CRELD1 TLE6 ERVK13-1 UBE2G2 TMEM147-AS1 TMCC1-AS1 ATP5S PYROXD2 ZNF605 IFT22 C20ORF166-AS1 ST3GAL3 ZNF710-AS1 CARMN RIOX2 AC093752.1 ADAM11 ADAMTSL1 GATD1 ADAMTS19 FBXO18 PLSCR5 2-MAR C14ORF159 AC004233.3 Top 500 upregulated genes in mouse fat with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/wjs3QjflY STAT3 NMI DGAT1 DDX58 RRP9 CXCL10 IFITM3 RNPEP PF4 TOR1AIP1 SCCPDH RASA3 LAP3 STOML2 ST3GAL4 STAT1 TRIM25 B2M EIF2AK2 POR MOV10 ISG15 AGPAT2 UAP1 IL10 MX1 MYD88 PGM2 SPTLC1 DDT PSMA2 SGTA NINJ1 IFI27 METTL7B OSMR ISG20 C2CD2L PRPS1 C1QC RMDN3 PARP10 LGALS3BP TOR3A DHRS7 STEAP3 C1QA SUMF2 CORO1B GPD1 BST2 TKT HCAR2 LTBR SLC1A5 NCLN AK2 PNP MILR1 ME1 MGST1 TMEM106A POMP IFI44 OPN3 HADHB SLC1A3 C1QB EPSTI1 GAPDH C2 BATF2 PSMB2 SPATS2L LDHA SLC43A3 PER3 DRAXIN TGFBR2 ZFP36L2 AXL CYCS EHHADH SREBF1 MAP2K3 CDK2AP2 DCK PSMA3 BCL3 TNFRSF1A HELZ2 OGFR SBNO2 RSAD2 OAS3 IRF7 ZBP1 NLRC5 IL18BP GBP5 TAP1 CLEC5A IFIT1 RETN ACKR1 IFIT3 RTP4 OAS2 SIGLEC1 XAF1 PSMB8 GINS1 DHX58 USP18 CMPK2 IFIT2 TGM1 PLAC8 TIMELESS UNG HERC6 IFIH1 MLKL STAT2 PML PLEKHA4 SOCS3 CCL11 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L XDH PTGES DAXX GBP6 HPSE CASP4 RNF213 IFI35 PARP14 SLC25A22 SOCS1 TRAFD1 MITD1 PARP11 GFPT2 UBE2L6 AIDA TLR3 UBA7 GBP7 SP110 LGALS12 ANGPTL2 DBP RBP7 PSME1 CLIC4 PSME2 SHISA5 LY6E IER3 IRF1 PSMB10 CHMP4B ICAM1 DTX3L IRF9 JUNB PSMB9 GBP3 VEGFA GPAM ACAT2 NR1D2 LYVE1 RNF114 TAPBP TALDO1 SLC39A1 NDUFA1 PSMA6 CAPZA2 THEMIS2 FASN FXYD1 DBI SAR1B PMP22 PGRMC1 SCAND1 ZC3H12A TBX3 CSF1 SRPX NATD1 SUGCT CIART TLCD2 LGI2 TMEM120B SERTAD1 BHLHE40 ZNFX1 TSPAN31 PSMA4 PTTG1 YPEL5 ZNHIT1 TSPAN4 MFSD5 APEX1 NIT2 PSMA7 CMC1 MRPL17 PNPT1 ADSL TUBB6 SNX10 HSPE1 CDC25B TOB1 ARL6IP1 ID1 MTFR1L CD47 LRRN4CL SLIRP NNMT TAP2 SLFN5 CASP1 ASB13 ZCCHC2 TOR1AIP2 TRIM21 RNF31 MOCOS TAPBPL TIMD4 FAM46A ZC3HAV1 TRIM5 RBM43 TRIM14 ANKFY1 MAP2K1 MRAP SLC27A1 DDX60 RNF19B LGALS9 SP100 MX2 GINM1 SLC22A4 LIMA1 WHAMM SOD2 PARP3 TAF10 CASP8 PDK1 NXNL1 RTN4RL2 CADM3 SDC3 ODF3L1 RASL11B AKAP7 KCNH4 IL21R CCL12 CCL7 OLA1 PEX3 NTSR2 XBP1 HMOX2 SPG21 ANXA7 TNFAIP8 BAK1 SP140 PSMC5 HMBS OAS1A OAS1B COQ2 PEX19 APIP IRAK3 ATG3 BHLHE41 ABHD16A BST1 ABHD5 GGCT FFAR2 KCNS3 AACS MPC1 ACSL1 TMCO4 CCL9 OASL1 SNX2 LRPAP1 PRKCE DNPEP GDA KEAP1 CDC34 SRA1 ACACA IIGP1 DERL1 EIF4EBP1 DRAM2 CCL6 COQ10B SETDB2 ALDH1L1 NR1H3 SLC5A6 TDRP ACSS2 LMO4 MT2 AIFM2 HCAR1 PSMA5 IFRD2 IPO4 TEF CASP12 H3F3B TXN1 PLOD3 UGDH TMEM14C PDHA1 H2-T23 MT1 CTDSPL HSD17B12 CHCHD3 MRPL30 PXMP2 SLC25A1 SDR42E1 NSMCE1 RAB34 IDNK IL1RL2 RPP25 SNTB1 PEX13 IGTP GBP9 H2-T22 GM4070 H2-Q4 GM4951 IRGM2 SLFN4 APOL9A LY6A GBP10 TRIM30A IFIT3B C1RA TGTP1 IFI47 IFI204 GVIN1 TGTP2 IRGM1 OASL2 ALDH1A7 APOL9B SLFN2 MS4A6C IFI211 SERPINA3N OAS1G C1RL FCNA MNDAL TRIM12A FCGR1 MS4A6B MS4A4C IFI205 MS4A6D NT5C3 IFI209 PHF11D PHF11B TRIM30D PEX16 NUDT7 IFIT1BL1 H2-T24 TRIM34A SLFN8 SLFN1 9930111J21RIK2 IFI206 XRN2 IFI203 IFI213 SMPDL3B SPRYD7 SYNE3 TMEM120A PDP2 RGL3 SORBS1 GPR146 IFITM6 ZFP703 PEX14 CCDC25 MFSD8 5-MAR CPNE8 LSM1 ATXN10 10-SEP SSBP4 ASCL1 SLC43A1 PCSK4 F830016B08RIK GBP11 IFI208 GM8995 IFI203-PS BC023105 9130208D14RIK IFI207 IFIT1BL2 GM20559 G530011O06RIK PHF11A GM5431 GM43197 CD209F COX18 BSCL2 MOCS1 NMNAT3 ETFBKMT MGL2 AC122018.1 RAI2 GM29458 9530082P21RIK B430219N15RIK CBR2 GM20684 GM26637 SASS6 AC151730.1 C1QTNF12 ADGRD1 GM5460 GM16685 MPC1-PS C130012C08RIK 1600014C10RIK MS4A8A EXOC3L2 SLFN9 GM16675 GM4841 GM6548 ZFP503 AKR1B7 2810474O19RIK OLFR56 TRIM12C GM12250 TRIM30C ELMOD3 9330175E14RIK GM8113 GM45418 GM28875 GM37310 PLPPR3 4930599N23RIK GM16168 ISOC2A APOL7A Top 500 downregulated genes in mouse fat with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/wjs3QjflY SPTB CEP250 NIN CNTRL APLNR SEC14L1 UBD STX3 MACF1 SECTM1B CACNA1D MAST4 VIL1 PRRC2B COL4A3 GGT1 NPTX1 TTN AQP2 HNF4A PKLR MYO7B GIPC2 AASS ALDOB EGFR ZC3H12C FGFR4 RNF128 MIF4GD MYO10 NBEA TMC5 ENAH BEND7 SLC15A2 SLC40A1 FGFR2 NT5E YAP1 FMO3 NFAT5 ELF3 LMO7 PBX1 PEAK1 MARCKS FNBP1L ADGRG1 ANK3 PLEKHG1 PLA2G15 ADCY7 KSR1 ATG16L2 ITGAX PIP5K1C RGS12 PSD4 NRP2 MYOF PAX8 SNX32 NREP MYO1E RRM2 ITGA1 PADI2 UNC13B SH3PXD2B RAPH1 PLEKHA1 IL7R MGAT4A MATK TFDP2 CGREF1 CDKN1A CNOT6 PTCHD1 PKD1 CDH1 MAPT SPINT1 LAD1 CEP170B IFFO2 MROH1 PROM2 LAMA5 SPARCL1 RAB4A NAV2 ATF3 TBC1D8 GLI2 CUEDC1 NBEAL2 RAB11FIP3 KCNJ16 ARHGAP27 SLC37A2 CENPA RGS1 CREG2 IQGAP3 SLC29A3 ULBP1 TOX TNIP3 KCNN4 MYO1F TNNT2 CASQ2 TRDN TNNI3 PLA2G5 CDH16 MMP12 NFIL3 ARNTL GLT8D2 PIPOX CALML3 TRIL BTG2 DPYSL2 THBD TSPAN13 DGKZ MYL2 ST5 CLIC5 BTG1 LIMCH1 GIMAP8 NSMF ESAM IVNS1ABP PHLDB2 FSCN1 CD9 THBS2 STARD9 NOS2 F2RL3 EGFLAM ESRRG LONRF3 MPP4 ARHGAP25 CCL28 POU3F3 PDZK1IP1 CKB MBD4 GJA1 CDC7 TNFRSF21 LEO1 HSPA2 MXI1 SOAT1 MALT1 DNAJA4 RAPGEFL1 OGT ADRA2C MAP1B FRMPD1 RNF19A FAM129A SMIM1 USP43 ODF3B SHROOM4 GRAMD4 MFAP4 PAQR5 LAT2 TMEM252 CEP131 CCDC153 STAP1 CRACR2B PLET1 ATP6V0D2 TESC GPRASP1 FIRRE FBLN7 CFI PDZK1 PRPS2 SLC47A1 TTC3 CORO2A ARMC2 LPCAT1 CCDC173 BBS4 CD83 CX3CL1 RRAGD MDK BLNK RNF149 PRKCH CUX2 MAST3 ITGAD MEX3A BMF MRGPRE PTPRE GRAMD1B CACNA2D3 CHKA DPEP2 DCST1 ADAM19 SLC16A10 ADAM8 ALPK3 RHBDL3 MMD2 ANGPT2 CCL22 ZDHHC1 PRKCD CD93 RIN3 RET KIT PGF FOXJ1 CXCR4 SPRY1 B4GALNT4 STK10 ADAM22 SPP1 RDH16 ACOT1 ZFHX2 KCNJ2 DLL4 SYNE1 AKAP13 SYNE2 KIRREL3 SYNM KLC4 CACNA1A PLXND1 SLC38A5 PCDH12 DTX4 TBC1D9 ABR LRRFIP1 ABLIM3 ITPR1 HIPK2 SPHK1 DCHS1 PDGFA ATP6V1G2 VSIG10 GLS ZFHX3 SLC5A3 MMP7 IGF2R KCND3 ADRA2B NPAS2 LRRN1 PLXNA1 KMT2A VSIG8 SIPA1L3 TRPM4 FERMT1 CBL AMOT SLC16A14 GALNT6 PIK3C2A MBOAT2 DAPK1 BIK WDFY3 DDIT4L PRKCG APOA1 NOTCH4 KCNA5 HAVCR2 ABCB1A XYLB TGIF1 COL5A1 TNC WSB1 AFDN LNX1 TRP53INP1 RGS6 SOX4 PPP1R1B ST8SIA4 HRK MMP15 DNASE1L1 TMOD1 ENO3 FAM81A SEL1L3 TANC2 GGA3 RUSC2 FGD6 MOK KIF21B RPGRIP1L ARHGEF19 IZUMO4 CSGALNACT1 MICAL2 FAM49A PGAP1 FAT4 FAM43A SRGAP3 MCOLN3 LRRC8C TES ECM2 APBB2 MKL2 SERTAD4 BTBD3 SZT2 HIPK1 PKHD1 CDK18 TEAD4 NOCT HSPG2 AHDC1 CFAP54 FRYL KMT2D FBXL20 KSR2 ZHX3 CHD3 GABBR1 CACNG4 CYP2D22 HDAC11 SLC25A13 PRKCB TCF20 CCDC88C INO80D CAMK2B CCNJL MFAP3L GAN KCNK1 MIGA1 ZMYM1 SLC4A8 ADARB1 MTURN SLC6A8 ITPR2 PDE4C PALD1 ANKRD37 INAFM1 DNAL1 CLOCK TLE2 EPN2 CADM1 MYOCD SPSB4 KLHL3 SOGA1 IQCD MINK1 TRAF3IP1 FAT3 CLIC6 PLXNC1 TTC21A LPIN3 LILRB4A MS4A14 CHD5 RGS7BP SLC17A7 1700020I14RIK GNAO1 SRSF10 RNF180 ZFP69 LRRC74B CCDC157 TRRAP CFAP74 INTS6L OSBPL3 PLXDC1 COL28A1 P3H2 TTLL3 FSD1L SCN8A LRRC75B KCNC2 AMHR2 PACRG MAML3 WNK3 CFAP65 SERPINB9B CFAP70 IGHV6-3 DNM3OS GM45396 RAB6B B130024G19RIK SNCAIP UCKL1OS 4933439C10RIK C77080 ZFP704 F730311O21RIK AI314278 MIR6392 DACH1 CDH23 4930578C19RIK 9530026P05RIK MARF1 GATSL2 CBFA2T3 ZKSCAN16 KITL ARNT2 FAM150B ZFP185 CDK20 TCTEX1D4 GM5086 MUP-PS21 TULP3 1700012P22RIK TMEM132B ZFP420 GM26703 2900026A02RIK UPF2 APH1C RGS11 6330403L08RIK GM867 RGS9 ZFP219 2310015A10RIK PPP4R1L-PS TMEM132C ASPN CASKIN1 LYRM9 1700003E16RIK OLFR558 B230354K17RIK TM4SF19 1700024P16RIK DNAH10 1700025G04RIK D630003M21RIK TRP53I11 PPP1R36 STAC2 KNDC1 TRIM67 ARHGAP27OS2 GM45605 STRA6L DCSTAMP B930095G15RIK GM15800 GM45836 9430020K01RIK Top 500 upregulated genes in mouse heart with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/6736vPDTl GLA JAK1 CNTRL FKBP10 FGL2 ABCC1 SQSTM1 DDX58 MPP5 RBL2 CXCL10 IFITM3 AP3B1 LYN JAK2 SLC46A3 USP2 QSOX2 STAT1 TRIM25 EIF2AK2 USH1C HERPUD1 USP54 PABPC1 ITGA4 ISG15 TMED5 LNPEP SLC44A2 MX1 NSUN3 INTU 2700046G09RIK CPT1A PLSCR2 TMEM86A TMEM71 TNFSF10 TSGA10 HS3ST1 GULP1 IL33 HLF COBLL1 FREM2 CD180 DSG2 FAM214A GADD45A MALAT1 ISG20 PLA2G7 TACC2 ABCA1 IFFO1 UNC93B1 ARHGAP30 ITGB2 PTGER4 LSP1 LAIR1 C1QC PARP10 LGALS3BP RNASEL MICAL1 TOR3A C1QA LRRC25 MBD1 BST2 SLC6A6 MILR1 SCARB2 RAB20 KCNE1 TMEM106A IFI44 TMTC1 SLC1A3 C1QB EPSTI1 ACVR1B HEXB ALDH9A1 NRIP1 PER3 PTCH1 MLF1 TFDP2 MYC TGFBR2 PIK3IP1 MPEG1 AXL BMP4 HPGDS CYB561 NFIC DCK TMEM88 CTSC RERE HELZ2 OGFR DDR1 HCLS1 RSAD2 OAS3 IL10RA IRF7 ZBP1 AOAH NLRC5 IL18BP PYCARD GBP5 GATM TAP1 PLD4 CLEC5A ERCC6L IFIT1 CCDC88B SLAMF9 CCR5 PTPRC FYB LY86 CLEC7A GLIPR1 MYO1F CTSS FABP4 MYOM2 IFIT3 RTP4 TLR7 OAS2 CD86 SIGLEC1 XAF1 CH25H PSMB8 CD274 CYP26B1 GBP4 DHX58 CYBB USP18 CMPK2 IFIT2 CNGB3 HERC6 IFIH1 STAT2 RAMP1 PML TCIRG1 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L GBP6 CASP4 RNF213 IFI35 PARP14 SLC25A22 SAMHD1 F3 UBE2L6 UBA7 GBP7 WARS SP110 ANGPTL2 PCOLCE2 DBP DDC UCP3 SCN7A CD200 SHISA5 LY6E MYOZ2 BMP6 IRF1 TXNIP DTX3L IRF9 PSMB9 GBP3 GPAM NR1D2 RAP1B TAPBP GLUL IFI30 LAPTM5 MKNK2 ALOX5AP HCK THEMIS2 NCF4 EFHD2 SERINC3 ART1 PDZRN3 CREB5 AOX1 LGI4 CSF1 ART3 TLR9 IKZF1 CYTH4 CIART FUS AQP4 CHAC1 PFKFB3 SLC25A33 TSPAN4 UBE2G1 SNX10 TCF15 TMEM245 DNAJB9 MKRN1 ARGLU1 ANKRD1 CREBRF KLHL24 TIFAB GLCE CD47 LRRN4CL IFT46 ZBTB22 EBI3 TRIM21 TRIM56 TIMD4 ZC3HAV1 TRIM14 PDK4 ANKFY1 PIK3CG DGAT2 CYS1 DDX60 XRN1 SP100 MX2 TMEM140 GINM1 FNIP1 ANKRD12 TM6SF1 FAM179A LIMA1 TMEM57 FMR1 SRGN SRSF11 PLEK ARHGEF3 LONRF1 DGKE SDC3 NCF1 APBB1IP CD68 SLCO5A1 PRKG1 IL21R CORIN FAM26E TLR8 RIT1 TBXAS1 PIK3CD NPC1 RECK TRIM63 OAS1A OAS1B STX12 RNF115 IRAK3 BHLHE41 CLN6 CIRBP MID1IP1 XYLT2 KCNJ2 GPCPD1 USP53 PTP4A1 FILIP1 PPAT CDH4 ALPK1 CRY2 RSAD1 IRAK4 CCL9 OASL1 PLIN3 ADSS SNX2 PER2 HDAC4 TRPM7 KDM6A TRIM24 ARHGAP32 SMC4 IIGP1 SYNJ2 VSIR EIF5A2 BCL2L11 EIF4EBP1 CCL6 COQ10B EEF2K LEPR SLC30A1 ZBTB25 RAB7B MTHFD1L TBC1D15 SLC22A5 GCLM SYNPO CBLB MT2 CYGB TEF PODN CASP12 DOCK2 H3F3B SHC3 H2-T23 LYZ2 IFI27L2A H2-D1 MT1 H2-AA TNIK RHOBTB1 TBC1D5 CPD PCDH7 DOCK11 NABP1 ZC3H6 HNRNPDL ASXL2 MYO5A RAB34 DHRS3 SLC20A2 PRRG4 CPEB3 FBXL20 PDE1C IGTP H2-EB1 GBP9 H2-AB1 H2-Q4 IRGM2 FCGR4 SLFN4 LY6A TRIM30A IFIT3B IFI47 IFI204 VWA5A TGTP2 H2-Q6 IRGM1 OASL2 SLFN2 MS4A6C OAS1G ABCA8A MNDAL TRIM12A FCGR1 MS4A6B PIRB MS4A4C IFI209 PHF11D PHF11B TRIM30D H2-T24 TRIM34A SLFN8 SLFN1 IFI206 XRN2 IFI203 IFI213 ARHGAP15 APOBEC3 ARMCX3 SAMD5 SLC12A4 CCP110 TTC33 UVSSA PDP2 HIVEP3 SORBS1 HELB FAM134B SPATA6 TNXB WNK4 FAM76B MTBP DZIP1L FAM69B MMRN2 IFI208 GM8995 IFI203-PS BC023105 IFI207 1810026B05RIK APOL10B GM20559 KLRA2 GM5431 CLEC4A3 GM1966 STK35 TTC30B ANKRD16 ADAMTSL3 NUDT13 MTM1 RFFL GNPTAB STUM CPEB1 CARMN ETFBKMT 9530082P21RIK SLFN9 GM4841 GM6548 TRIM12C GM12250 9330175E14RIK SERPINB6B ADAT2 H2-T10 9330158H04RIK ADGRF5 ZFP945 GM20633 FAM76A 1110034G24RIK CD300C2 ZFP383 GM11837 3110002H16RIK BBS9 BC022687 HTRA4 GM10603 ZFP386 ACTR3B MS4A4D E230013L22RIK AC133498.1 ZFP445 GM45909 C1QTNF7 GM44645 LMOD3 9130011E15RIK SV2A GM37891 ZFP970 C1QTNF9 EMCN 3425401B19RIK ZFP280C Top 500 downregulated genes in mouse heart with SARS-CoV-2 infection from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/6736vPDTl DCAKD SYVN1 NINL HYOU1 SEC14L1 LARP1 DNAJC11 MOGS NUP62 MACF1 CCND3 DDI2 ZC3H18 COL4A1 TUBA8 TUBB4B KCNQ1 GNG5 PMEPA1 BAG3 GPAA1 TUBA1A UBTD1 BCS1L CALM3 SLC27A4 COL4A2 TUBA4A VSTM4 HSPA8 MARK2 TMPRSS13 EDEM1 PLEC ATXN2 BPNT1 UNC119B OSBPL6 OLFML2B SLC15A2 YAP1 ITGA10 MAP6 EFHD1 RPS13 AADAT TMEM94 RELT ATP1A1 GPAT4 PTPA NACC1 MAPK8IP3 ATG16L2 TOR1B ARHGEF10L EMC10 EHBP1L1 CLUH TMED9 MRPL12 ELL2 MCM2 PDGFC MZB1 PAQR4 POLQ AMPH TPM2 CACNA2D2 NUAK1 CDKN1A NOTCH1 SERPINH1 MAVS MANF LRP2BP ACTB NECTIN1 JAG2 GTF2IRD1 SLC7A1 PYGO1 FGF11 RAB4A NAV2 ATF3 MAP3K4 SLC8A1 STK40 PWWP2B NBEAL2 RAB11FIP3 SLC12A7 ARHGAP35 RXRA PHC2 SCAF1 PRR12 SLC37A2 HSPB3 MYL4 ADAMTS4 LRRC3B NFIL3 HAND2 KLHDC8A ARNTL PDE2A SCUBE2 ATP2B2 GSG1L TMCC2 BTG2 KLF4 CNN2 ACTG1 DUSP1 THRA FGD5 TMEM204 JUN VEGFA ADAMTS15 RPS21 NSMF SH3PXD2A DDX17 ATF4 CRELD2 S100A16 ERRFI1 TUBB2A DNAJA1 DNAJB1 HPS4 SLC38A2 TMEM256 ANK1 TSPAN18 DUSP8 AOC3 COL13A1 FBXL22 CCND2 EDNRA ASB2 SPON2 RTN4R NPDC1 PDE4A SORBS3 CITED4 TMEM178B CLN8 LGI2 BBC3 PPRC1 ALAS1 GTF2E1 PGAM1 STIP1 WDR83OS LEO1 EBPL HSPA1A CHTF8 SPSB3 CCDC117 USP10 TAF4B MN1 REEP1 DNAJB5 SNX15 REL RAP1GAP2 TATDN2 EXTL3 PNPLA3 SSNA1 TFRC ACTN4 PRKD2 FGFR3 CABP1 GPRASP1 ABAT MLEC KPNA6 RCAN1 DUSP4 SLC35E2 IRS1 GALM BRI3BP CERK PACSIN2 MYL6 THAP2 SOBP BANP ZKSCAN3 EGLN3 PNCK NR0B2 LSMEM2 ITGB6 ROR1 TRPM3 PRODH2 ADRA1B RNF125 ITGA6 TNFRSF25 NUBP1 TADA3 XBP1 AP1B1 DFFA TRAF2 PPP4R1 TMX2 SZRD1 KCNJ15 DCUN1D2 EPHA4 URGCP MPP3 NACC2 OPA3 INPP5E P4HA1 CDK10 CAMKK1 ATXN1 SYNE1 FAT1 EEPD1 MAZ ADCY5 BCL6 STK24 PARVB FOXK2 PLXND1 PRDM2 ATP6V0A1 ATP6V0A2 PCDH12 AMOTL1 TIMM13 ABR LRRFIP1 FLNC ARHGEF15 PPP1R16B RPS6KA2 DCHS1 WDR1 ELN PPARA GRK5 SLC5A3 ROBO2 SREBF2 SRF NPAS2 HCN4 PLXNA1 SLC22A3 TMIE MUC4 VWA1 P4HA2 DYRK2 HSF1 MAPKAP1 FBXW7 SPHK2 UBIAD1 BHMT2 PPP2R5A SLCO3A1 CYP2U1 KIF6 IGFALS MUS81 NFYA MTFP1 SIAH2 GLS2 PIN1 SART3 NTN1 MMP15 XIRP1 PNKD SLC41A3 ANAPC16 KLHL18 DIP2C ZBTB48 TIAM2 KDM5C KDM2A ABTB2 FAM168B MRM1 HS6ST1 CTXN1 TMEM141 DNLZ ARHGEF19 SHB FAM49A MAN1A2 MTSS1L MBOAT1 SULF2 PPP1R3C FRMD5 EIF4EBP2 RASGRP2 CLMP PDE3A DGCR6 TMEM53 HSPBP1 NR2F6 ADAT3 ICE1 ZBTB40 ADGRA3 GALE ZMIZ2 SLC35F6 RBM10 IRGQ GRIP2 TBC1D16 KMT2D GTF2H4 JOSD1 ZHX3 CCDC69 MPRIP TTC28 PRLR GSTT3 AMY1 MUP11 PRRC2A SAFB2 B3GALNT2 IRF2BP2 MICALL1 HSPA12A PDLIM7 MSL1 CAMK2B RDH5 RASIP1 TSPAN9 COL5A3 MESDC1 MGAT3 SNRNP35 SLC6A8 NDNF RGL3 ADGRL1 ARHGAP39 CLOCK STRIP1 CDIP1 TLE2 FAM220A SMIM11 TIMM22 NUDT4 SMG5 D17WSU92E TSC22D4 LDB2 MTUS2 COLQ TRABD GDPD5 CROCC PTPN23 RFXAP MRPS17 SAMD4B TESK1 AMIGO1 ZFP276 ZFP142 SLC12A5 ANO4 ZFP651 DUSP3 RIMS4 RAVER2 MAD2L1BP INPP5J PROB1 SMG9 MDP1 FAM78B DACT3 KCNK3 RHOJ PRRT1 CLASP1 IGSF1 TMC7 NT5M GRB14 SH3GL2 NOV MYADML2 RAB6B CDH23 6330403L08RIK 2310015A10RIK LYRM9 TRP53I11 GM15800 0610040J01RIK MFSD4A DCDC2B BANF2OS GM34302 GM28231 DNASE1L2 KLHL30 GM10069 LINGO3 GM11734 GM42878 5830417I10RIK LZIC GM17029 4631405J19RIK CUZD1 9-MAR RMDN2 DVL3 KBTBD12 GAL3ST3 PRR33 ANKS1 DDX55 ABRA ZNRF1 TMEM74B ZFP296 4632404M16RIK FAM124B ZFP213 GM12002 FAM212B 4930590J08RIK GM35339 RBM12B1 ZFP410 AI464131 4931428F04RIK ZFP568 C130080G10RIK SLC2A4RG-PS 6430548M08RIK GM44597 BC049715 CYP2C44 FV1 METTL11B GM9899 PTPN9 TTC7 2310022B05RIK CXX1A ZFP319 PERM1 MIGA2 AC166750.1 GM17546 KCNG2 ACSM2 2410131K14RIK GM5105 2510039O18RIK PKNOX2 ZC3H8 GM42937 RTP3 GM10435 TMEM25 GM45531 Top 500 upregulated genes in mouse kidney with SARS-CoV-2 infection (Day 3) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/a1bjr8RJB ENDOU FGL2 COL6A1 NOX4 VCAM1 STAT3 HECTD1 PCK2 DDX58 CREB3L3 IFITM3 TMPRSS4 RASA3 SLC6A19 FBLN5 CENPF SMAD3 SLC7A9 ATM FN1 VSTM4 STAT1 PDE4D FMNL1 FBN1 EIF2AK2 PCNT ISG15 ASAH2 LNPEP IGSF9 MX1 DHTKD1 KLF1 KLF12 PITPNC1 MPP7 CPT1A SERPING1 OSBPL6 SLC22A23 RARB ZEB2 IL33 OSMR CFH CD180 FZD6 CYBRD1 TJP1 ISG20 ABCA1 AIF1 PNPLA2 SLCO2B1 C1QC PIEZO1 PARP10 LGALS3BP ACSS1 DHRS7 C1QA TGFBI BST2 LRP1 SLC6A6 GAS2L3 TOP2A CCNB2 SCARB2 IFI44 HMMR ANO5 KIF2C UACA C1QB ADAMTS2 BRCA2 MKI67 SLC43A3 PER3 LAMA2 COL5A2 COL1A1 ABCD4 MPEG1 AXL ABCG1 HNF1A COL14A1 CARD14 ARTN EVPL LAMA5 FGF18 COL1A2 LRP5 DIXDC1 IRF8 F2R TFCP2 PRC1 IQCE HELZ2 COLEC12 ARHGAP11A OAS3 IL10RA IRF7 ESCO2 ZBP1 NLRC5 GBP5 CKAP2L TAP1 CX3CR1 IFIT1 RACGAP1 ZWILCH CD72 CORO1A LY86 POLE MYO1F CTSS IFIT3 CD84 RTP4 CDT1 TLR7 OAS2 C3 SIGLEC1 XAF1 PSMB8 CD274 GBP4 DHX58 CHAF1A USP18 CMPK2 IFIT2 EVI2A CD300LF TGM1 PLAC8 HERC6 IFIH1 CPXM1 STAT2 RNASE4 PML PLEKHA4 ADAR NAMPT TIFA PARP9 PARP12 XDH RNF213 PARP14 TRAFD1 SAMHD1 UBE2L6 ANGPTL4 UBA7 GBP7 SP110 EPHX1 ANGPTL2 DBP SLC35F3 SCN7A TTYH3 IRF1 TMCC3 ICAM1 DTX3L IRF9 PSMB9 GBP3 DCN CPNE7 NR1D2 MGP DDR2 EVA1B LBH MYLIP THEMIS2 PREX2 CYP2S1 TRIM46 SCAND1 ART4 AOX1 VAMP1 TNFAIP3 TLR9 INSR FOXK1 GNA14 ZNFX1 PFKFB3 SH2B3 TSPAN4 DHX40 IPO5 TMEM245 PLEKHG6 SERINC5 HNRNPA0 PTPRD TXNDC16 ITGAV SLFN5 GSDMD TRIM56 ZC3HAV1 F13A1 WDFY4 CD38 CYP1B1 NID1 AFAP1L2 BBOX1 DUSP9 C6 CFI DDX60 MAN2A1 DDHD2 SLC26A2 LGALS9 TNFSF13B XRN1 SP100 MX2 SMC5 IGFBP1 FNIP1 ANKRD12 LIMA1 WEE1 JADE2 PIK3AP1 RAB31 PDXK P2RY6 SLC25A42 KLHDC8B SMOC2 DAPK2 ENTPD1 LOXL2 SDC3 APOE CXCL14 LAMA3 ADCYAP1R1 LAMC3 CXCL12 C4B IFNGR1 CCL12 OLFML1 NAAA TNFRSF1B POSTN EXOC2 OAS1A OAS1B WIPI1 FBLIM1 DENND2A CIRBP XCR1 GPCPD1 USP53 TEX9 HNRNPD AACS PTCH2 PXDN CRY2 RHBDF1 DKK3 OSBPL5 PDGFRB PLEKHM2 RSAD1 OASL1 PPARA IGF2R EFEMP2 TRIM24 PNPLA7 RALGAPA2 PTPRF INHBB ASXL1 ATOH7 CBX7 IIGP1 PITPNM2 SYNJ2 MREG CCL6 CMKLR1 RORC ZBTB25 AP4E1 RAB7B PTGIR MTHFD1L SLC5A6 ABCA6 POU2F1 COL5A1 IGFALS CYP27B1 CYGB NEIL2 NOP53 H2-T23 LYZ2 IFI27L2A H2-AA TMEM87B FITM2 BAHCC1 TTC39B CNKSR3 DSEL DECR2 RAB36 AFAP1 NMRK1 CCDC14 ZC3H6 ANKRD28 CCBE1 DNAH17 PDPR CDK18 A4GALT 7-MAR DCLRE1C FBXL20 SYNPO2 ODF2 LY6C2 EMILIN1 GBP9 GM4070 H2-AB1 H2-Q4 GM4951 IRGM2 FCGR4 SLFN4 TRIM30A IFIT3B IFI47 C1S1 IFI204 GVIN1 VWA5A OASL2 APOL9B SLFN2 SERPINA3G IFI211 OAS1G GSTT2 ABCA8A MNDAL TRIM12A FCGR1 MS4A6B IFI209 PHF11D PHF11B TRIM30D UPP2 H2-T24 DOCK10 TRIM34A SLFN8 SLFN1 IFI206 XRN2 IFI203 IFI213 ESYT1 SH3BP5 RELL1 RUBCNL LRP4 WDR19 SYNE3 COL15A1 ITIH5 UVSSA ARHGEF40 SNX30 GPR146 ARIH2 SPATA6 TNXB ATP1A2 SYNPO2L PGGT1B IQCD CEP57 MICALL2 CLASP2 SLC25A34 MMRN2 ABHD15 GM45221 GM42664 IFI208 GM8995 IFI207 CHRNB2 GM20559 PHF11A GM5431 GM1966 GM43197 HTRA3 ACSS3 TCHH THBS4 RBM26 URI1 MTMR10 HEMK1 ANKRD16 KCNB1 RUNDC3A ACVR2B MFSD9 NPTXR CPEB1 ETFBKMT 9530082P21RIK AC151730.1 ADGRD1 GM16685 SLFN9 GM12250 MS4A4D ZFP280C GM10804 ABCA8B H3F3AOS PCX AKR1C13 C78859 D130007C19RIK ADGRA2 6430571L13RIK 2810459M11RIK NAT8F3 B230303O12RIK ST6GALNAC5 E230016M11RIK GM16755 GM44956 GM11788 CILP CLCA3A1 GM26797 2410002F23RIK MORN4 CEP83OS LHFP NAT8F4 CAAA01147332.1 GM12946 GM16348 ZKSCAN17 GM45051 B930025P03RIK MDRL GM43672 EFCC1 GM37206 GM23935 ADAMTSL5 A330035P11RIK GM44899 TTLL10 4833411C07RIK GM11613 A730049H05RIK MYOC N4BP2L1 Top 500 downregulated genes in mouse kidney with SARS-CoV-2 infection (Day 3) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/a1bjr8RJB UBB SLC10A2 ERICH4 SYVN1 HSP90AB1 SUMO3 HSPA5 SLC6A18 GLYCTK HYOU1 MOGS ANKS4B YWHAG TIMM9 NGDN RBX1 ELAVL1 KHK NDRG1 TUBB4B ECSIT ZBTB7B COL4A3 BAG3 SIGMAR1 HSP90AA1 FAM162A HMOX1 AQP2 UBQLN1 TMEM39B SLC27A4 TUBA1C TUBA4A MRPS25 CNDP2 GLOD5 PHB NEDD8 AFM HSPA8 TKFC UBFD1 LRRC1 SIPA1L1 LRRC8A CLDN10 2210011C24RIK FAHD1 ASB9 ALDH8A1 DHRS1 PSMA2 SGTA HOXC6 MIF4GD SLITRK6 UQCR10 SLC15A2 MT-RNR1 NT5E ITGA10 MT-RNR2 RPL13A RPSA BEND5 HTRA1 RPL31 PDIA6 ARHGEF10L PNPLA6 GNB2 DNAJB2 TBC1D10B BSDC1 TRIM65 CLUH TMED9 CMTM6 GLMP DHCR24 PNP SLC16A1 FRRS1 MGME1 DEPDC1B ERLIN1 NDUFS4 ROGDI NME1 DYNLL1 SPATS2L MRPL51 GNPDA1 CGREF1 CDKN1A SERPINH1 MANF ACTB CYCS IMPA1 JMJD6 SREBF1 WNT7B PYGO2 FGF1 JAG1 CDK2AP2 CCDC170 ATAT1 HMX2 PICK1 TRIM8 PLEKHG3 LRCH4 SLC29A3 CCK SUCNR1 FABP7 NFIL3 LIPG ARNTL DDC UQCRB CRYAB ATP5J NPNT CYB5A MDH2 NDUFA13 PSMB6 PSMC2 PRDX5 PSMB5 PSMD3 CCKAR PABPN1 SRP14 NDUFB7 CHORDC1 CCT3 ATF4 CRELD2 HSPH1 CALR NDUFV3 CTU2 TUBB2A DNAJA1 DNAJB1 CFDP1 NDUFA4 CCNL2 IGFBP5 ATP5J2 MIEN1 CACYBP RBM8A DDIT3 ASXL3 MYCT1 TTR TMEM258 OST4 ERI3 DPM3 CIDEB TMEM205 NDUFAB1 HSP90B1 PGAM1 CKB WRB TAF12 LAMTOR5 PSMB3 SRP9 STIP1 MRPL42 EBNA1BP2 SLC25A15 EMG1 NDUFA8 AHSA1 NIT2 ETHE1 POP5 HOXB7 SSR2 NAA10 LEO1 HSPA1A CHTF8 SPSB3 DNAJB4 PPM1H NEAT1 MSMO1 RNF25 SQLE ID2 HTR1B MCM6 MVD MKKS SLIRP RNFT2 COX10 PTMS CYS1 AARS AHSA2 TSTD2 FAM149A CHAC2 STX16 SLC47A1 DNAJC22 IGSF11 BOP1 TCTA HPS5 GMPR SLC35E2 NEFL IRS1 EIF1 MAP3K7CL SARAF KANSL1L BANP ZKSCAN3 OSGIN1 SLC17A3 GREM2 ITGB6 WSCD2 UPK1A SLC35F1 ANGPT2 HSPA1B PSMC4 PSMD7 COPZ1 PHF5A PSMD11 SNRPD3 TXNL4A RIT1 RNF5 DPP9 FAAH ATP2A2 ESD ERP29 SNX6 FKBP2 COX20 COQ4 GON7 TOMM22 UBE2F DCUN1D2 ATP1B3 AKIRIN2 CSRP2 GGCT ARMC6 FAM193B NDUFAF4 TSPAN14 TSPAN5 OPA3 ECHDC2 DNAJB11 PTER PDIA3 ARHGAP24 ALDOC DNAJC2 P4HA1 IPO13 MVK TRABD2B MBD3 PDRG1 TFEC EIF1B METTL3 KCTD10 PELO NOC2L NDUFA11 VSIG2 ARFRP1 HEXIM1 APEX2 PPARD SELENOK ACOT9 APELA SLC14A2 SLC5A3 NPAS2 TRMT1L SEMA6A TRA2A MAP3K5 TRPV4 HSF1 BIK AQP8 SPHK2 GPR137B ACMSD HAAO SERPINF2 SULT1C2 TRAF4 HAX1 KMT5A MET SIAH2 RBM38 RRP36 HUS1 HN1L HNRNPAB CCDC137 MMP15 MAP2K2 SLC35B1 TMEM14C PI4K2A AHCYL2 JOSD2 TMEM19 BCKDHB KDELR2 BCL7C NOP2 GGA3 CNOT4 RBM14 KIF12 NSDHL PCYT2 MYL6B ARHGEF19 NCCRP1 UBA5 CCDC6 MCOLN3 HOXB9 NABP1 APBB2 FBXL19 HSPBP1 ZBTB40 CAMSAP2 MRPL21 PALLD NOP16 MED19 EIF4G3 JOSD1 ZHX3 BTNL9 PALM3 PCTP HIST2H3C2 AMT B3GALNT2 MRPL44 SLC9A8 CAMK2B SLC25A48 TYW3 AVPR2 TTYH2 PYCRL RNF186 ARHGAP26 MINOS1 PKNOX1 CLOCK STRIP1 FAM220A SPPL2B KAT8 NOB1 RDH10 SLC35E1 HHATL CCDC97 GPR137 INO80E TMEM132A MED11 TMEM64 DESI2 CTDNEP1 NCBP2 HABP4 MTMR4 GPD2 MRPL38 ZBED3 RPP25L OLFR1396 SNRPN IGF2BP1 SLX4 MED28 GATC INTS8 DCTN5 FBXO46 TEPSIN DCLK2 LARP1B DLEU7 GATAD1 ADAL UBE2G2 AI314278 UPF2 DNASE1L2 ZNRF1 GM35339 TMEM25 UGT2B38 D930016D06RIK CYP2D12 5730559C18RIK GM853 GM43428 BC017643 RBSN ZFP692 1810017P11RIK AKR1C21 GM15344 GM42670 B230216N24RIK ZFP35 AI838599 0610031O16RIK DUSP15 PANTR2 GM3716 GM12940 ALG12 KBTBD4 LDAH RSLCAN18 INSC GM2415 SNHG18 IGFN1 SLC22A22 RDH1 AC132474.1 TCAIM 1600020E01RIK FAM184A AC122301.3 TMEM150A GM27216 ELAVL3 GM45645 9530085L11RIK GPR137B-PS AC147512.1 AC123720.1 DHRS7B BC004004 BOD1 4933434E20RIK GM15318 HOXB3OS SLC39A2 BGLAP3 TRPM1 UGT8A BC037034 BCL7A KAP GM43158 AC151971.10 GM45775 SLC22A28 1110019D14RIK D630023F18RIK FXYD4 ZSCAN22 ST6GALNAC3 DOC2G A330023F24RIK PDZRN4 Top 500 upregulated genes in mouse liver with SARS-CoV-2 infection (Day 3) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/uUEGxhyW0 DCTPP1 ERMP1 RBL1 CD14 CNTRL SUN2 NMI 2010003K11RIK PCK2 DDX58 TOR1A EPB41 IFITM3 TOR1AIP1 TMEM97 RASA3 COQ8B SERPINE1 CFP CTSD NR3C2 STAT1 EIF2AK2 ACY1 PCNT ISG15 EVL MX1 1700001L05RIK AQP11 SIAE CPT1A GPR155 IFT122 GYS2 TMEM86A DEDD2 TNFSF10 IFI27 COBL LMO7 HUNK FNIP2 STEAP4 FZD6 SLPI LCN2 CCND1 PNPLA2 ARHGAP30 ITGB2 ARID5A LSP1 C1QC PARP10 LGALS3BP TOR1B ARHGEF10L TOR3A C1QA GRINA SH3BP2 CORO1B BST2 SLC15A3 MARCO GRN HCAR2 LTBR SULT1A1 DHCR24 TOP2A CCNA2 NEK2 MARVELD1 IFI44 HMMR SPAG5 MCM2 KNSTRN IRF5 CDK1 BIRC5 C1QB UAP1L1 LAMC1 ACVR1B CDCA3 CDC20 HP KIF20A PER3 FGFRL1 MGAT4A NTRK1 ABCG5 BMP7 ABCG8 TGFBR2 SLC2A5 AZIN2 MPEG1 CCNE1 MTOR PLPP2 CYB561 DACT1 IRF8 FZD4 MAP2K3 DCK PRC1 TCF3 TNFRSF1A SYTL1 LFNG OGFR ATG2A ERF SAA1 HCLS1 ARHGAP11A RSAD2 OAS3 IRF7 DENND1C ZBP1 NSL1 GINS2 NLRC5 GBP5 CHAF1B TAP1 FANCD2 BRIP1 GZMA TACC3 NUSAP1 MCM5 IFIT1 KIF20B CORO1A HMGB2 LY9 CENPE CTSS FCER1G IFIT3 RTP4 CDT1 OAS2 SIGLEC1 XAF1 PSMB8 CD274 CYP26B1 DHX58 IL1RN USP18 CMPK2 IFIT2 CD300LF DHFR TGM1 PLAC8 HERC6 KIZ IFIH1 MLKL PML ADAR NAMPT PARP12 SAMD9L XDH GBP6 SMC1B RNF213 AIM1 IFI35 PARP14 TRAFD1 SAMHD1 UBE2L6 TLR3 UBA7 GBP7 SP110 EPHA1 LRAT DBP SHISA5 IGFBP4 PSMB10 IRF9 PSMB9 GBP3 NR1D2 TAPBP BNIP3 HEXA LAPTM5 LRG1 HCK THEMIS2 EFHD2 SAT1 MYO18A HPS4 FBF1 POU2F2 GNAT1 MBP CSF1 SPP2 ADORA1 RIMS3 SERPINA10 VCPKMT SOCS2 ASB2 HIC1 CIART TBC1D30 ZNFX1 SH2B3 RNASEH2A PLGRKT GSS TSPAN4 MICU2 MMS19 SLC10A3 GMNN IPO5 SNX10 AMIGO2 PLEKHG6 RIPK3 HMGCR KLHL24 KDSR MCM6 ZBTB22 STAP2 SLC6A9 P2RY13 CSK CLEC4F S100A8 SLFN5 TLR2 TRIM21 BID ZC3HAV1 SELL RIPK2 WDFY4 ATP6V0D2 BMPER CLDN14 SLC20A1 DDX60 IFT74 RNF19B SP100 MX2 SNHG12 ANKRD12 RNF145 BCO1 LIMA1 WEE1 RELB BLNK TRIM26 PRTN3 CSF2RB PDXK CD52 KLRK1 LTB ST6GAL1 BMF MRGPRE LONRF1 GREM2 SDC3 ENPP2 SLC38A3 PLSCR1 SAA2 CD68 ACP5 PTPN1 C4A USB1 PILRA LIPE NPC1 IFNGR2 PLBD2 ANXA7 LARS2 BAK1 OAS1A OAS1B DHX35 STK10 BHLHE41 ARL8A CLN6 GPCPD1 PGPEP1 GPRC5C P2RY2 AMDHD2 KLHDC7A ALPK1 CRY2 GNL1 SUN1 UCK2 RIPK4 TMCO4 PRSS8 RNASEH2B OASL1 ZBED5 TRIM24 CDK19 TNKS1BP1 SLC37A1 DNMT3A IIGP1 CLMN SYNJ2 BCL2L11 COQ10B CARD10 RORC CTBS ENPP1 FOXA3 SLC5A6 CYP2A5 ORM2 SLC23A2 NIPAL1 MT2 AIFM2 PPIF MCM3 NEIL2 TEF DOCK2 JAML RILPL2 TMEM51 H2-T23 IFI27L2A MT1 H2-AA SLC41A3 ZBTB48 IL17RB NMRK1 SLC35D1 GFRA1 NGEF ZC3H6 SACS DCLRE1A BRAP SIPA1L2 DCLRE1C HOOK2 ODF2 SWAP70 LY6C2 IGTP GBP9 H2-T22 GM4070 H2-AB1 IRGM2 SLFN4 APOL9A LY6A TRIM30A IFIT3B IFI204 GVIN1 IRGM1 OASL2 APOL9B SLFN2 SERPINA3G MS4A6C C4BP IFI211 SERPINA3N OAS1G PRG4 MNDAL TRIM12A FCGR1 PIRB IFI209 TRIM30D UPP2 H2-T24 TRIM34A SLFN8 SLFN1 IFI206 IFI203 IFI213 APOBEC3 EDA2R NRG4 P2RX7 SLC12A4 BIN3 ANGEL2 LRP4 DNAJC10 SYNE3 RBP1 TMEM120A GPR146 CABIN1 H2-BL IGHD TSC22D4 SLC36A4 TCTN2 ATP5SL MTBP MIIP PCSK4 IFI208 GM8995 IFI207 APOL10B KLRA2 PHF11A GM1966 STK35 RCL1 PLEKHG5 SFI1 TBC1D1 B3GALT1 URAD CPEB1 ST3GAL3 9530082P21RIK AC151730.1 SLFN9 GM6548 TRIM12C GM12250 TRIM30C C77080 H2-T10 FAM76A TTC7 GM10804 ZKSCAN17 GM15564 EFR3B AI429214 MIR6236 GM5150 ZFP867 1700028E10RIK PHC1 3110082I17RIK GM21049 MFSD7C TRIM30B 1110059E24RIK OSBPL2 GM14097 B430306N03RIK PCBP4 CYP3A59 BC025446 GYG AP4M1 GM19705 BC021767 GM11963 GM31105 CEP57L1 GM8883 GM26684 ZCCHC11 GM14403 Top 500 downregulated genes in mouse liver with SARS-CoV-2 infection (Day 3) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/uUEGxhyW0 AP2A2 CEP350 SYVN1 SUMO3 HSPA5 SLC17A4 HYOU1 APC MDN1 SPOP ERGIC1 SLC45A3 KPNB1 MOGS GCC1 UBQLN4 YWHAG NDRG1 TUBB4B ZBTB7B BAG3 SIGMAR1 HSP90AA1 MRPS27 NCK1 ENPEP UBQLN1 GGCX TUBA1C TUBA4A TARS USP48 SLC16A6 HSPA8 AGPAT2 DIAPH1 GSK3B UBFD1 EDEM1 RCOR1 GLO1 USP34 WDR89 KLF12 4932438A13RIK ATF5 NCOA5 MIF4GD MYO1B SLC15A2 DUSP16 RAI14 NFAT5 BDP1 MAP7 NEDD4L TAB2 KHSRP PTPA DNAJB2 CAD TYMP PDIA4 TRIM65 SMARCD1 CLUH TMED9 ACLY NET1 PNP SLC16A1 PSEN2 SEC23B PDGFC ITSN1 GLDC LIPA RAPH1 LRFN3 ZFPM1 CRY1 AKAP12 TJP3 MARS MANF ACTB CNOT3 JMJD6 NECTIN1 CELSR1 PROSER2 SCNN1A WWC1 TCF7L1 DDHD1 HNRNPH1 CDK2AP2 FPGS PREB ATAT1 ZCWPW1 GRID1 TECPR2 KIF13B TNK2 CREBBP TBL1X PLPPR2 CCNF KYNU SUCNR1 NFIL3 ARNTL ATP2B2 DDC TFG CLIC4 THRA HMGCS1 FGD5 SMAGP PXDC1 GPAM LUC7L3 BTG1 PABPN1 MBNL1 TSC22D3 SH3PXD2A CHORDC1 HSPH1 CALR CCNL1 TUBB2A DNAJB1 VCL TMEM147 RBM8A DDIT3 SPON2 VASN GGNBP1 ANP32A MAGT1 SLC29A1 STIP1 SLC25A15 SYNCRIP ETHE1 LEO1 SPSB3 MRPL18 DNAJB4 USPL1 FKBP4 CKAP5 COL7A1 INSIG1 HACL1 MCU BLCAP MCC MVD ODF3B TRA2B ASB13 ATF6B CREM PDK4 PIKFYVE MRAP IARS GPRASP1 AHSA2 FAM13B FAM149A PNKP SMC3 NEB TFPI2 PSTPIP2 GFPT1 RFX7 FAM210B COPG1 GLUD1 IRS1 U2AF1 AMPD2 S1PR1 BANP ZKSCAN3 GAS1 CBS CLK1 CHKA SLC17A3 PIGA SEC14L2 ADRA1B AMDHD1 HSPA1B ORMDL3 AASDHPPT CSTF3 SCO2 CLPX AGO2 DNM1L CREB1 DPP9 BACE1 SC5D ATP2A2 SEC22B IL11RA1 STX18 UBA6 ABCB11 HAPLN4 CITED2 CAPRIN1 FAM193B DNAJB14 PHC3 EML4 MED24 AHCTF1 ZCCHC7 TXLNG P4HA1 TMCC1 ADCK5 PPP1R3B TTLL12 REPIN1 PPDPF TAF1 PCDH12 DTX4 SLC25A44 DOCK6 TXNDC11 GMPPA HEXIM1 SGPL1 KPNA4 GRK5 SLC5A3 INSIG2 G6PC GAS7 NPAS2 AVPR1A STK38L MEGF9 TMIE JMJD1C PDE9A TRA2A PIK3C2A MGAT2 ZBTB21 TARDBP RAET1E MREG LRRC59 AQP8 SPHK2 UBR4 RAET1D CTH ABCA2 ZFHX4 UBXN4 TRIP11 AP1G1 UBXN7 GBF1 CYP2U1 PPM1B LEAP2 ACSS2 SLC10A5 MAP3K2 CARMIL1 MTFP1 ATF2 NFATC3 SIAH2 TXNRD2 TMED3 HSD3B7 SELENOI CS PNKD OSBP GMEB2 SRPRB FNDC3A RBM14 PMVK PLEKHB1 EBP MICAL2 LGALSL SHB FNDC4 PXMP4 PGRMC2 CEP44 SRGAP3 HSPA13 MYRF MKL2 ZBTB40 DSTYK MED13 SZT2 ADGRA3 WAPL ZSCAN29 MACROD1 MAGIX DHRS3 GALE KMT2E PDE8A RFXANK RBM10 SOS1 PALLD BRWD1 HNRNPA3 CAPN15 IRGQ PAOX ARID4B ARL4A CPEB4 KMT2D DERL2 TMEM41B PBLD2 CYP2B9 CAR8 7-SEP AOX3 AMT PRPF4B USP37 B3GALNT2 INO80D IRF2BP2 CCDC127 CAMK2B PIGN DAB2 ALG2 PIP4K2B NKTR HINFP FAM213B EXOG XKR6 COMMD7 YPEL2 CLK3 CLOCK NAT10 XPO7 STX5A ZFP110 NELFA ZFP385A AFF1 SLC39A9 SSR1 OSBPL8 DUS1L GPR137 DESI2 EML3 RNF144B CEP97 CRYBG3 MTMR4 PRKCI GPD2 SLC18B1 GALT ZFP982 LUC7L B3GAT3 AGO3 SRCIN1 BCO2 FUT11 NKIRAS1 CCDC159 TTLL3 NECAB1 ELOVL3 SNED1 SLC30A10 FAM210A ZFYVE16 ADAL CDK20 STRA6L RMDN2 GM35339 RTP3 1810017P11RIK GM12940 ALG12 INSC SLC39A2 SLC22A28 A330023F24RIK 1810017P11RIK GM12940 ALG12 INSC SLC39A2 SLC22A28 A330023F24RIK GM7463 BC024978 GM43690 AI480526 INTS2 AC162181.1 ZFP638 ZFP658 HNF1AOS1 GM43597 ZFP652 9930021J03RIK TMEM170 TMEM263 EDRF1 2900097C17RIK CAR14 ZFP236 ZFP592 GM43681 ZFP780B RABGEF1 ANKS3 RD3 ZFP329 BC029214 3110062M04RIK AC153899.1 GM2061 ZFP9 CMAH ZFP950 WRAP73 ZFP54 GM16314 11-SEP 1700066M21RIK 1500017E21RIK 0610030E20RIK 1110002J07RIK 1600002H07RIK 9030616G12RIK 1110020A21RIK CATSPER2 GM16731 5033403H07RIK 4732465J04RIK 4930556M19RIK RIC8B INTS10 GM37729 NAPB MFSD4B3 CYP2C53-PS GM20257 SIMC1 SPCS2-PS AC160029.1 ACNAT1 ACAT3 CNNM4 GM45301 ZFP397 C330006A16RIK AC152061.1 ZFP369 GM17530 COQ8A GM15832 ZFP260 CAMK1D MIS12 ATP2A1 ZFP451 MAPK15 GM15401 CYP2J9 SPG20 ZFP933 4921513D11RIK Top 500 upregulated genes in mouse lung with SARS-CoV-2 infection (Day 3) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/6Cg35VDfn IGSF8 FCGRT SFTPD CD14 FGL2 ERLEC1 NPTN NMI DDX58 AGRP IFITM3 TOR1AIP1 SLC46A3 GPX1 USP2 TREM2 STAT1 CNDP2 EIF2AK2 AGTRAP STOM ETV5 ISG15 SPI1 MX1 ESM1 SRR ARSG HPN SLC25A16 HOXA7 CPT1A GPR155 PLSCR2 TMEM86A TNFSF10 FRK RGS2 IGSF6 HLF S100A14 SMPDL3A CD300E SGPP2 PRSS23 PLA2G7 LCN2 TPD52 TC2N ITGB2 LAIR1 LGALS3BP ARHGEF10L TOR3A ALOX5 LRRC25 EMILIN2 TGFBI BST2 SLC16A3 SLC15A3 GALNS SLC11A1 PNP MILR1 LMO2 SAP30 IFI44 MCEMP1 SERPINB10 MS4A4A H1F0 IL18 LGALS3 ABCD1 CCR2 HEXB LIPA CLEC12A PER3 RHEBL1 S1PR5 SLC2A6 AZIN2 PIK3IP1 MPEG1 AXL HES2 LRRC8E MMP3 FOXL1 MMP8 DIXDC1 NUCB2 UPP1 TMEM88 CTSC OGFR RSAD2 OAS3 IRF7 NKG7 ZBP1 AOAH TCF19 GINS2 GBP5 CHAF1B PLD4 CLEC5A GZMA CX3CR1 IFIT1 SLAMF9 CLEC7A MYO1F CTSS FCER1G S100A9 IFIT3 CD84 RTP4 TLR7 OAS2 XAF1 CH25H CYP26B1 DHX58 CTSK FBXO39 CYBB GPR141 IL1RN USP18 CMPK2 IFIT2 ARL11 EVI2A ALAS2 TRIM10 SNCA PNLIPRP1 CLEC4E PLAC8 CD177 IFIH1 MLKL LGMN TREM1 ADAR TIFA GBP2 PARP9 PARP12 GCH1 DAXX CASP4 IFI35 TRAFD1 GPR35 C5AR1 UBE2L6 GBP7 ATP2B2 ANGPTL2 DBP SORD ACER2 LY6E PLVAP DTX3L SPARC IRF9 RIPPLY3 GBP3 S100A4 CTSH NR1D2 MGP LYVE1 RNF114 TYROBP FXYD5 ALOX5AP RNASE6 HCK GM2A ELOVL1 SAT1 PPIC FPR2 OIT3 LST1 ART4 NAPSA BHLHE40 HAUS1 YPEL5 TSPAN4 EIF2A EXTL2 AMIGO2 SGMS2 LIPF ARL6IP1 SRXN1 ID2 TIFAB F10 ZBTB22 SUSD3 NCR1 VRK2 PRF1 S100A8 TLR2 TOR1AIP2 TRIM21 MOCOS F13A1 CCRL2 WISP2 IL15 FPR1 ATP6V0D2 KRT79 CD38 NFE2 CYS1 ATP1A3 APOBEC4 ANKRA2 RASD2 DDX60 METRNL CD302 LGALS9 SP100 MIR22HG MX2 PSTPIP2 UCP2 RALB PKIB PLK2 WEE1 RNF149 HOGA1 CTSA SRGN MSRB1 CHP1 HMGN2 CDA CASP8 GZMB PLEK BMF PPFIA4 LMCD1 OSGIN1 NR4A1 GPR21 CD68 TLR8 TRAPPC1 TRIM17 PILRA TBXAS1 CD300A LILRA5 FGR NCF2 PGF TNFRSF1B CTSF QARS OAS1A PI4K2B BHLHE41 CLN6 BST1 ABHD12 CIRBP TGM3 STBD1 EIF2AK1 ALDOC FAM49B ANKMY2 P2RY2 AMDHD2 TREML4 INPP5K HBP1 TRIM62 CCL9 OASL1 PRCP SGK3 KLK1 DGKG SRPX2 NFAM1 BMX LEFTY1 PDE9A ARHGEF37 HID1 INHBB IIGP1 VSIR GSR RAB32 EVA1A CCL6 PRR5L SETDB2 CD300LB KLRB1C HACD4 RAB7B CYP39A1 EPOR CDKN2D TEF OGFRL1 TMEM51 H2-T23 LYZ2 IFI27L2A WFDC21 HBB-BT OAZ2 MFSD1 NECTIN4 MPV17L2 NCCRP1 DTD2 ZC3H6 CCBE1 CLEC11A SLC35F6 SSPN LY6C2 IGTP GBP9 H2-T22 GM4951 IRGM2 FCGR4 SLFN4 APOL9A LY6A TRIM30A IFIT3B TGTP1 IFI47 IFI204 TGTP2 IRGM1 OASL2 APOL9B SLFN2 MS4A6C IFI211 SERPINA3N OAS1G HDAC11 ECI2 PBLD2 CAR8 CHIL3 FCGR1 WFDC17 MS4A6B MS4A4C MS4A6D IFI209 FCGR3 PHF11D PHF11B TRIM30D IFIT1BL1 H2-T24 TRIM34A SLFN8 SLFN1 IFI206 IFI213 CARD9 SMPDL3B BIN3 RAB3D ADGRL3 SLC17A5 IFITM6 TBCEL DOK1 SLFN3 TMEM163 EXOC6 SKAP2 SHC2 SIRPB1A AW011738 CLEC4A1 LY6I IFI208 BC023105 9130208D14RIK IFI207 TLR13 SIRPB1C IFIT1BL2 CD300LD APOL10B KLRA2 PHF11A GM5431 CLEC4A3 I830077J02RIK ITGBL1 GRTP1 TMEM116 URI1 NMNAT3 ETFBKMT GM26637 MS4A8A OLFR56 GM12250 TRIM30C SERPINB9B FAM76A CD300C2 2810459M11RIK NAT8F3 GM5150 3110082I17RIK B430306N03RIK GM14403 GM5483 ADGRE4 1110059G10RIK EAR2 A130051J06RIK SIRPB1B A530064D06RIK NLRP1A GM9889 NXPE4 TREM3 CYP2AB1 TMEM200B GPR33 LYZ1 UGT1A7C GM1976 9930014A18RIK 2310007B03RIK SH2D1B1 LRRC29 2210406H18RIK ADSSL1 5430437J10RIK KLRA3 TNFSF13OS PILRB2 GM15931 CLEC4A2 AC157570.4 MLC1 EAR1 NAIP2 AC118222.2 GM4956 CUTC GM44616 CGRRF1 AB124611 VTI1A SKINT3 OAS1C CYP4F16 ZEB2OS GM9733 UNC119 KLRB1F GM45218 BC147527 CLEC4N I830127L07RIK GM16845 BRD7 DNAH2OS ASPRV1 GM42835 IL1F9 C130050O18RIK Top 500 downregulated genes in mouse lung with SARS-CoV-2 infection (Day 3) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/6Cg35VDfn TIMM10B TARS2 SYVN1 HSP90AB1 HSPA5 HYOU1 MDN1 SLC45A3 MOGS UBQLN4 XPNPEP2 BAG3 HSP90AA1 PLOD2 RBM28 USP11 FOXA1 UNC5CL TLN2 EGFR HSPA8 UBFD1 PLEC PDE4DIP ATAD3A 1810019D21RIK NCOA5 SLC15A2 ITGA10 ANKRD33B INPP4B MYO5C ATG16L2 THBS1 DNAJB2 CAD TYMP TRIM65 MYO1E IGHG1 LDLR GLDC PRRT4 AMPH CD163L1 CCR3 KY TRDC TSPOAP1 SLC1A7 MSC BMP7 CDKN1A TUFT1 SERPINH1 CILP2 MAPT SNPH AR JMJD6 WHRN PTK6 JAG2 MST1R NKD2 MAPK11 DVL1 ATAT1 SLC24A3 TRIM8 QPRT ITGB1BP2 CDH26 NTRK2 CACNA1G NFIL3 SLC39A14 ARNTL SCN3A SCN7A TOX2 CYR61 MYL2 DUSP1 COX17 HMGCS1 SH2B1 MAT2A PABPN1 SNRNP48 SH3PXD2A CHST1 CHORDC1 BMS1 HSPH1 DNAJA1 DNAJB1 UBE2V1 HPS4 CNTN1 ZDHHC18 NOVA1 DUSP8 ADAMTS17 TBX3 NR4A3 ASXL3 SYNGAP1 SERPINA10 KBTBD8 NACAD SPON2 SAMD15 TG CCL28 FLRT3 PPRC1 MND1 WDR12 STIP1 NOP58 PUS7 ST13 LEO1 HSPA1A CHTF8 HSPA2 MORC4 CCDC117 HSPA4L USP10 MUM1L1 HSPD1 KLF7 DQX1 MNS1 HSD17B7 HMGCR BLCAP TTF1 DPH2 MCC IL1R1 PCYOX1L DNAAF3 STXBP1 ADPRHL1 ACAP1 RASL11A PRKD2 MAP1S ANKRD13B LMAN2L CABP1 IARS GPRASP1 AHSA2 ADAM1A ADAT1 TAF1A NOL9 SLC47A1 TTC3 POGK ARMC2 GFPT1 HOMER1 JADE2 IL18R1 TRAF5 BANP ZKSCAN3 MIR17HG RBM12 SNHG17 FHL2 CHKA PIGA COL12A1 ADAM12 ADAM8 HRC FCHSD1 PCDHGC5 ASPG SV2C HS3ST3B1 HSPA1B TNFRSF25 IDI1 CAMSAP1 RIN3 RET DPP9 RAB4B CARS2 ARMC6 P4HA1 DHX29 AACS IGSF9B LSS SMPD3 TELO2 BCL6 CACNA1A FOXK2 PRDM2 PCDH12 RBM6 DTX4 URB1 FLNC TXNDC11 PPP1R16B PCDH1 LRIG1 IL23R APEX2 TNNI3K SLC7A6 PPARA SLC5A3 SREBF2 ZBED5 NPAS2 KCNJ5 AVPR1A LMTK2 PLXNA3 CTTNBP2 SRPK1 DLEC1 BHLHA15 DPY19L3 DAPK1 PROX1 CPT1B NPAS4 NCAM1 COL5A1 SFPQ MUS81 SENP8 NFYA FUBP1 TNC CREB3L1 IRS3 HDAC10 RGS6 POLR3E REXO4 CCDC137 IPO4 GRWD1 WDR4 CCDC134 PLA2G4B AHCYL2 BCKDHB PEG10 NEURL4 ARID3B USP31 BICD2 TTPAL RBM14 DHCR7 SAMD1 MMAB PCYT2 TMEM201 IZUMO4 PWP2 MFSD2A UBA5 RBM20 PPP1R3C RASGRP2 ANK2 ZDBF2 CLMP FBXL19 INTS1 TBC1D4 ZBTB40 RASA2 GRAMD1A STK36 NOCT SUGP2 POLR3D SMYD5 ZSCAN20 DIRAS2 PALLD AHDC1 GRIP2 TTLL4 SYNPO2 PRG4 AMY1 SCD1 RBM12B2 VAV2 CEP95 USP37 IRF2BP2 HSPA12A CAP2 CLASRP CAMK2B RRNAD1 USP35 MED20 CCNJL COL5A3 TUBG2 FASTKD1 FAM222B PKNOX1 METTL1 FKTN POLR1B CES2G TRP53BP1 DDX51 EFNB3 MYOCD HHATL COLQ PPP1R26 PTPN23 SNAPC4 NEK8 MYLK4 MTMR4 SIX5 IKZF4 CNTNAP1 OPCML PIEZO2 TTC21A ACRBP AMIGO1 TMEM181B-PS ZFP276 ZFP142 AW551984 SH3RF3 PRMT7 LRRC71 TRMT61A CFAP74 WDR66 PCDHGA12 CTRL LY6K MYLK3 DAW1 HEATR1 INTS3 CDH24 TTLL3 TMC7 S100A7A CCDC136 GPRASP2 RAB6B F730311O21RIK ZFP420 6330403L08RIK CASKIN1 DNAH10 GM45605 DNASE1L2 GM10069 5830417I10RIK DDX55 FAM124B FAM212B GM35339 RBM12B1 SLC2A4RG-PS GM9899 ZFP319 MIGA2 KCNG2 RTP3 C78859 ZFP692 GM15344 GM12940 ZFP692 GM15344 GM12940 INTS2 ZFP592 GM43681 3110062M04RIK ZFP9 MAPK1IP1 LDHAL6B HSPA12B GM13071 GM32856 B130034C11RIK GM37154 GM44777 FOXS1 QTRTD1 EARS2 GM42979 1200007C13RIK 9330151L19RIK AIRN GM42868 ZFP607B ANKK1 GM15445 UTP14B D630045J12RIK D930048N14RIK GM15884 GM43852 GM13648 GPR156 GM27003 PRDM15 CACNA1B GM12941 GM36266 GM43759 BC034090 GM37019 WDCP ZFP133-PS METTL16 5830487J09RIK ATP8B5 ASB14 5830408C22RIK DNM3 SNORA31 UGT2B1 GM44280 GM45114 1700029I15RIK D330041H03RIK XLR3A TMEM108 SLC25A35 AC163040.2 IGKJ5 2700081O15RIK YIPF7 2310058D17RIK GM42717 GM43375 5430416O09RIK GM5737 3110056K07RIK GM20045 4930402H24RIK ZFP366 9430015G10RIK HMGB1-PS8 GM23458 C79130 AC157822.3 AC107819.3 OLIG3 C030034L19RIK GM25747 GM28151 A230072C01RIK GFRA2 JMJD7 TNFRSF22 GM13830 SNHG14 GM43860 H2-M5 TRIM3 PLP1 POMT1 GM37074 AC158605.2 2700038G22RIK GM13111 LRTM1 AC159193.2 CRIP3 HIST2H4 TNR ZMAT4 GM26578 TTC41 GM26606 CYP51 GM16310 ZFP672 Top 500 upregulated genes in mouse heart with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/zk4WhE2hW SPTB CEP250 CHPF2 CANT1 PIK3R2 SYVN1 ZFAND4 XPO6 LARP1 PFAS PTPN21 AKAP8 SCAP UPF1 TOR1AIP1 ZC3H18 PRRC2B DYNC1H1 BAG3 ANXA11 SPTBN5 PABPC4 TRIM25 VARS BAG6 USP48 USP54 PCNT PXN BRD4 MARK2 AKAP8L UBE2I UBQLN2 PDE4DIP ATAD3A POLRMT RILP SF1 BRF1 GATAD2B ANKRD33B MALAT1 TACC2 SRRT KHSRP SYMPK SLC12A9 IFFO1 MAN2B1 PIEZO1 MBD6 PCNX3 GAA USP19 GIGYF1 CAD KHNYN GGA1 CIC LRP1 ZSWIM8 EDEM2 INF2 ITGA5 SLC6A6 SNRNP70 NCLN ITGA7 MAFG ALDH9A1 RAPH1 CORO6 TNRC6C PBXIP1 ABCF1 OBSCN SLC2A8 EP400 CNOT3 MTOR AGRN BCL9L TMC4 SCRIB ALS2CL PPP1R13L MROH1 MYH14 PPP1R37 ITPR3 LAMA5 BCL9 NAV2 MAP2K3 ABCA7 SAFB PTH1R CCDC9 CUEDC1 MED25 FOSL2 PHF12 NBEAL2 KMT2B RERE AP2A1 CREBBP KDM4B HELZ2 PLXNB2 FBRS BRPF3 MNT RGL2 SCAF1 ULK1 GLTSCR1 SBNO2 SETD1B AGAP2 SYT12 AAK1 GBP6 SLC25A22 TRAFD1 SAMHD1 MYH7 TNS1 DGKZ U2AF2 GDPD3 VEGFA SH2B1 GPAM NACA PSMD3 LTBP3 PABPN1 CAMTA2 STK38 CCNL2 MYO18A MEGF8 KDM6B TBX3 DGKQ CCM2L PRDM9 SCN4A MYPN FUS INSR GPR157 SEC31B GGNBP1 SLC25A27 IRS2 PFKFB3 ACIN1 SEC24B WBP11 RSRP1 PAN2 NEAT1 LENG8 COL7A1 MARK4 MYH7B SFSWAP MLXIPL ACR AVIL ZCCHC2 RNF31 WDR90 SLC27A1 ANKRD13B SLC43A2 FNBP4 FIRRE LRRC45 CASC3 KIFC2 STX16 CHD4 GTF2I CNNM3 IGF1R CARM1 SLC22A4 HNRNPL SRRM2 CPEB2 SRSF11 SON MAST3 SLC25A42 KLHDC8B ATF7IP DOK7 KCNQ4 GRIK5 ETV3 ALPK3 CCDC62 REXO1 PUM1 ZDHHC1 DOT1L SPEN SYK MFSD2B TGFBRAP1 ADPGK ELL EEF1A2 RBM22 ADAM22 SEC16A NUDT8 CDC42BPB TBC1D17 FAM193B ANKRD11 MAN2C1 USP36 NOS1AP NDOR1 HMGXB3 KLHL21 MEF2D WDR81 TEP1 DUS3L AKAP13 MLXIP NCOR2 RNPEPL1 POLR2A ATP13A1 CRTC1 FBRSL1 YPEL3 JAK3 SKIV2L ATP6V0A1 CRY2 MYO9B FBXO31 ADCY6 MICAL3 PLEKHM2 NISCH VSIG2 FLNC FHOD1 LMBR1L DOCK6 FAM214B PRICKLE3 SLC12A3 NPR1 VAMP2 HDAC4 ARID1A KMT2A PIAS4 PTPRF WNK2 CAMKK2 ASXL1 TXNRD1 EHMT2 SETD5 SYNJ2 MCOLN1 AMBRA1 ATG2B VPS52 KAT2A ADAMTSL4 CRTC2 UBR5 UBR2 UBR4 RPS6KB2 PDCD6IP TECPR1 UHRF1BP1L ABCA2 MTA1 SCAF11 PARP4 PEAR1 SYNPO CBLB ERN1 CDK11B ARNT PATZ1 DFFB DHX37 IPO4 LATS1 PODN ARHGEF1 JAML PLCG1 TEAD3 ACSF2 TIAL1 KANSL3 ATXN2L SCAF4 RBM33 FOXJ2 NEURL4 GGA3 ARHGAP17 RNF111 RUSC2 MED13L TADA2B PDZD2 GSE1 SFXN2 HS6ST1 IZUMO4 PHRF1 RNF40 CPSF1 ZMIZ1 ZCCHC14 TBC1D4 DIDO1 SZT2 TNRC6A GRAMD1A MAP4K2 LONP1 KREMEN1 GPATCH8 KMT2E ZMIZ2 SETD1A TJAP1 UBE2O SPACA6 RECQL5 CAPN15 GRIP2 FRYL KMT2D FBXL20 USP20 NDST2 EIF4G3 CUL9 GABBR1 GBP10 CYP4F13 SIDT2 BC005537 RBM25 ZFP740 BAZ2A PRRC2A SAFB2 ESYT1 WDR26 FNBP1 SBF1 APOBEC3 LUC7L2 DAG1 CLASRP HIC2 MLLT6 CIZ1 IDUA SLC12A4 ACACB SLC26A10 SPEG SLC4A3 ADARB1 FAM219A U2AF1L4 ARHGAP26 FASTKD1 PDE4C SRRM1 NKTR SORBS1 AATK PHF1 CHD7 POM121 CLK2 ZFP362 E4F1 UBE4B WIZ WNK4 HDGFRP2 CCDC97 CC2D1A ZGPAT DCTN1 PTPN23 MINK1 PRPF40B YLPM1 SNAPC4 DLGAP4 PALM CHERP MIIP KAT6B PRDM11 PCSK4 ZFP579 CPSF7 R3HDM1 MED12 TAF4 PROB1 TRRAP SYNRG CCNK FAM160A2 TGFBR3L ANKRD16 MAPKBP1 AP1G2 MIEF2 NRBP2 DTX3 DENND6B CSAD SCN4B PPP4R1L-PS DVL3 GM35339 SLC2A4RG-PS GM42937 ZKSCAN17 GM37206 ADAMTSL5 BC024978 AI480526 GM43597 0610030E20RIK GM42979 AIRN D330041H03RIK AC154347.1 BC002189 ZER1 AU020206 MIR5125 WIPF2 2900005J15RIK GM6977 ZFP446 KRBA1 ZFP697 ZFP598 AC160637.1 ZFP335 DLG5 GM22 GM12295 AC124556.1 NPFF 4930581F22RIK FLT3L GM44949 KCNT1 SBSN MORC2A GM10727 GM9754 GM26947 PRR29 TBX6 ZFP512B TRIM39 GM43481 8430422M14RIK GM28035 GTF3C2 GM15626 TBX3OS1 GCN1L1 2610306O10RIK ZFP839 GM14964 FAM65A Top 500 downregulated genes in mouse heart with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/zk4WhE2hW TIMM8B TBCA FCGRT CD34 NUDT2 YWHAQ NPTN FKBP7 SNX1 SLC1A1 ENPP3 ATP6V1A PDZD11 TPM4 RALA PF4 TMEM97 PDZD3 NDUFAF2 SCCPDH ANXA2 TUBA1A FAM162A NCK1 POLA1 ENPEP CALM1 CYB5R3 RARS PEPD ITM2A EIF4E NEDD8 PLS3 UAP1 ELOC DNAJC19 GGH LRRC1 DMXL1 MRPL35 MDH1 GLO1 APOOL HIBCH ADH5 ARHGAP18 TGDS CD55 OSGEPL1 DHRS1 CAV1 ISLR VKORC1 MYO1B RGS2 TM4SF1 MT-ND1 MT-CO1 METTL23 TSPAN6 FOPNL NDUFB2 ACOT13 PTPRZ1 CTSB KCNE1 GLRX SEC23B LGALS1 ANXA5 SDHD ALG14 BLVRA COMMD9 NDUFS4 TMEM45A CALCRL OLFML2A OSTC TPI1 MRPL51 PSMB7 MTERF2 MYH11 EPHB1 AKAP12 BMPR1A BMP7 MAPK8 IMPA1 SPARCL1 TMSB4X EDNRB ANKRD6 CTNNBIP1 RAP1A TMEM88 HACD1 PYCARD DHRS7C CASQ2 TRDN HSPB3 NPPA MB ITGA8 ACKR4 LRRC17 CAV2 SPTSSA UQCRB CD200 TNNC1 TUBA1B MYL2 TPPP3 SPARC MORF4L2 TMEM204 SEMA3C SH3BGRL NPNT UQCRC2 OGN CRIP1 ITM2C DPT PDE5A TAGLN CETN2 TCF21 DYNLT3 SMIM15 SDPR CHORDC1 NDUFV3 S100A16 CFL1 CDIPT COX6B1 TUBB2A DNAJA1 IGFBP7 DSTN CFDP1 VPS35 GNG11 NDUFA4 NDUFV2 EMC2 NDUFC2 ACYP2 RPS27L MRPS18C S100A10 PMP22 ATP5J2 GLOD4 COX14 CD9 CACYBP RGS4 SERPINI1 S1PR3 SNCG DUSP6 GNPDA2 HAT1 MRPL46 CMSS1 VAMP3 TXNDC17 MSRB2 CHMP5 TCEAL8 AP1S1 SARNP MTX2 SMIM20 MRPL13 IMMP1L MRPL42 ORMDL2 STK39 SDC2 ACTL6A EMG1 THYN1 NIF3L1 ATG5 SUSD5 TNFRSF21 MOB4 PDCD10 BZW1 MRPL32 SSR2 GTF3C6 KPNA3 MRPL1 UBA3 NAA20 STAG2 HSPE1 SEC23A TOMM5 TXNDC12 SKA2 CNN1 AKR1B10 MEA1 MSMO1 CSE1L BCHE CSRP1 MKKS MRPL47 SLIRP P2RY14 RXRG SSNA1 PDGFRL OTUD6B TMEM68 AHSA2 TMEM126B DCPS SNRNP25 TFPI2 BET1 SCGB1C1 MRPS11 SYNJ2BP THNSL1 EMP1 NOSTRIN SH3KBP1 RSU1 SRGN SEC61B RAB31 MYL9 CALM2 ARMCX1 ACTA2 CDC42EP2 FHL2 MLIP MCAM CDH13 DPYSL3 ACTG2 ANGPT2 IFNGR1 PGK1 HIKESHI TRAPPC1 SCFD1 VPS29 TIMM21 ANAPC10 QRSL1 PEX2 PET100 TEN1 POSTN SELENOF SNX6 HAUS8 TNFAIP8 FKBP14 COX20 CRLS1 IFT20 VTN UBA6 TMEM9B PRKRA DCUN1D2 ASAH1 COMMD1 COMMD3 CSRP2 DEGS1 STBD1 MFF COMMD10 NDUFAF4 TRMT2B DCAF4 RCBTB2 MED6 BBIP1 TMEM123 PTCD3 THEM4 MATN2 SMIM5 METTL22 CMC2 NDUFA11 FXYD6 TRIM13 PLN RNASEH2B ROBO2 INSIG2 NME6 TRDMT1 TRIQK RNF121 FUNDC1 MRPS22 NRAS CPQ GOLPH3L LUM IL13RA1 GSTT1 KIF6 ANGPT1 S100B CALU SENP8 DNAJC15 MGMT CCNG1 NDN PIN1 TCEAL1 ZC3HC1 LAPTM4B CCNC TMEM14C SDCBP COX7B ASPH HSD17B12 LAGE3 TMEM141 POLR3K TSPAN12 DCUN1D1 KLHL13 TUSC3 MFAP3 ECM2 TMX3 TOM1L1 QPCT HSPA13 CCDC90B TECR RFC3 COMMD2 CDR2 SACS NDUFS8 LHPP MRPL55 MRPL21 ARHGAP12 SNRPD1 MYCBP SCAI EEF1E1 MRPS14 LSM3 ZCCHC17 UQCC2 MRPL50 SDHAF4 SVIP COA6 C1GALT1C1 PDE1C LAMTOR4 AKR1C14 7-SEP MED21 ATP5F1 AKR1B3 HSPA12A MRPS16 PIGX B3GALT2 PDCL OMA1 SPRYD7 CNIH1 CXADR KCNMB1 PPM1F AAMDC SEC22A PRKCDBP MT-TI UROS SMIM11 PPP6C SMIM14 POLR1E WASHC3 PTGIS LSMEM1 GPR22 PKIA FAR1 LYRM7 SREK1IP1 EXOC6 MRPL22 NCBP2 TMEM242 DLD DPAGT1 10-SEP HTR7 NBEAL1 DNAJC24 GM38372 ITGBL1 S100A1 DUSP3 RPP21 FAM175B TSSC1 TEFM FASTKD2 SS18L2 MED28 NSMCE2 RPUSD4 EEF1AKMT1 NKIRAS1 AKTIP RNF141 TCEAL9 CBR4 NIPSNAP3B ASPN OLFR558 C1QTNF7 EMCN GM12002 GM17546 LDAH LDAH 1110059E24RIK ZFP54 ZFP260 1110059G10RIK ZFP931 SNAPC5 INTS14 CTLA2A GM45423 0610009B22RIK ATP6V0E PRRG1 GM15543 ELP5 6-SEP 2010107E04RIK 1810034E14RIK JAM3 TSTD3 1810037I17RIK NTM 2610001J05RIK AC163289.2 ZFP449 GM44250 4930523C07RIK CEP83 LRRC27 PCDHB16 COX8B BC028528 RAB28 AKR1E1 GM10039 ZFP719 FAM92A 3830406C13RIK AC160401.1 MOCS2 GPR37L1 6430562O15RIK 1700123O20RIK AC102435.3 SVBP PPFIA2 CEP19 GM43146 FAM212A GM45670 GM6419 PEA15A POT1A Top 500 upregulated genes in mouse kidney with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/ZPnYkqjkJ SLC36A1 CEP250 CNTRL NINL PFAS SLC4A9 AKAP8 CACNA1D EP300 DDI2 FBXL12 NLRP6 BAIAP2L2 GRIPAP1 ERBB2 ARHGEF11 EPS8L2 LGALS4 NOS3 BRD4 AKAP8L UBE2I IGSF9 1810019D21RIK CNTD1 DALRD3 SF1 IKBKB BRF1 CCDC84 NFAT5 PLEKHG1 SRRT KHSRP IFFO1 TAOK2 ADCY7 MBD6 MAPK8IP3 THBS1 INPPL1 LDB1 USP19 GIGYF1 ZSWIM8 INF2 SNRNP70 SMTN HJURP SH3PXD2B MIB2 PER3 TNRC6C PTCH1 KANK3 NOTCH1 ABCC6 PKD1 EP400 FGFR1 CNOT3 NCOA3 SSH3 SEMA3F ALS2CL MYO19 ITPR3 LAMA5 TNK1 PRICKLE2 NAV2 LRP5 JAG1 PNN ABCA7 ELF4 RGS3 SAFB EDC4 CCDC9 CUEDC1 PHF12 NBEAL2 ST6GALNAC2 KMT2B RERE CREBBP HELZ2 FBRS PITPNM1 RGL2 ULK1 SBNO2 PLPPR2 ATG2A PRR12 DENND1C MYH6 STAT2 PLEKHA4 HAP1 SHANK3 VEGFA PABPN1 PLEKHG2 CAMTA2 RAPGEF3 CCNL2 DDX39B FAM160B2 USHBP1 TRIM46 KDM6B STARD9 CCM2L ADAMTS10 PRDM9 VAMP1 FUS ANO8 FOXK1 GGNBP1 MAPRE3 SLC25A27 CLCF1 NFKBIZ ZNFX1 ACIN1 SPRED3 MMS19 SEC24B RSRP1 AASDH PAN2 OGT ARGLU1 MSANTD2 NEAT1 LENG8 COL7A1 MARK4 SRSF6 MCC CD46 SMAD9 SFSWAP MLXIPL LMTK3 ADAMTS6 IL15RA ZCCHC2 RNF31 CEP131 CYS1 PRPF39 FNBP4 AFAP1L2 FIRRE LRRC45 KIFC2 SP100 STX16 PRRC2C TNRC6B TPRA1 PNISR SRRM2 ACHE MOB3C PHACTR4 GTPBP2 TRIM26 ACTN1 SRSF11 SRSF5 RCOR3 SLC25A42 KLHDC8B ATF7IP ZKSCAN3 DENND3 JARID2 SPRY4 FANCA GRIK5 KIF5A ASPG TNFRSF25 ZDHHC1 DOT1L MDM4 MFSD2B TRIM11 ROBO3 WIPI1 NUDT8 AP5Z1 CD33 CHKB FAM193B ANKRD11 MAN2C1 USP36 HOXC4 HELZ ANKZF1 ZBTB10 ZCCHC7 DPM1 NDOR1 MEF2D TEP1 ULK3 AKAP13 COL27A1 JAK3 HDAC7 TANC1 SKIV2L CRY2 TSPYL2 INPP5K ADCY6 FHOD1 LMBR1L ARHGEF15 DOCK6 ARAP3 TNIP2 SLC12A3 NPR1 VAMP2 SEMA4G PER2 ECE1 CLCN2 EWSR1 PLXNB1 SETD7 ARID1A KDM4A SEMA6A KMT2A SMARCC2 DAB2IP TRPM4 ABCC10 CBX7 MROH7 PITPNM2 ZFP609 NOTCH3 CRTC2 RPS6KB2 RBAK RANBP10 PARP4 NSD3 ERN1 ARNT PKN3 TOP3B ARHGEF1 PLCG1 COL16A1 MAP2K7 ARHGEF2 JOSD2 NYNRIN KANSL3 POGZ ATXN2L NFRKB RBM33 FOXJ2 TANC2 GGA3 ARID3B HMG20A ZBTB39 EPS15L1 MED13L BAHCC1 GSE1 SLC25A37 HIVEP1 MUM1 AFAP1 PHRF1 ARHGAP21 ZCCHC14 DIDO1 SZT2 SVIL TNRC6A LIMK2 GRAMD1A LARGE2 MAP4K2 GPATCH8 ZSCAN26 KMT2E BAZ2B PHF21A MYOM1 SUGP2 RBM5 SPACA6 CAPN15 GJC1 TCHP CPEB3 GRIP2 FRYL PPOX KMT2D FBXL20 RFX1 GBA2 MPRIP GABBR1 ODF2 TCTN1 SIDT2 H2-Q5 RBM25 BAZ2A SAFB2 ZFC3H1 LUC7L2 HOXA3 CLASRP RRNAD1 MLLT6 CIZ1 GAN LRP4 ARHGEF17 HOXD4 TNS2 SYNE3 SLC4A3 FAM219A UVSSA YBX2 DUSP11 PDE4C RGL3 BRD3 SRRM1 NKTR DNAL1 PROSER1 CLK3 TPCN2 TLE2 CABIN1 CLK2 KLC1 TNXB E4F1 MAU2 WNK4 PPP1R12B HDGFRP2 KCNC3 CROCC KRI1 MINK1 ATP5SL PRPF40B SNAPC4 CNTROB DZIP1L FIGN MIIP ATXN7 RTKN ACRBP PCSK4 GM43858 ZFP579 SULT5A1 SH3D21 CPSF7 LUC7L MED12 TAF4 SLX1B PCGF2 METTL17 BRD8 PITPNM3 SRCIN1 INTS6L ANKRD16 NRBP2 KMT5C DTX3 DENND6B HIP1 SNED1 KAZN ATXN7L2 CFAP65 4933439C10RIK RGS11 PPP4R1L-PS DVL3 ZNRF1 GM35339 SLC2A4RG-PS GM44597 GM42937 GM10804 ADGRA2 B230303O12RIK E230016M11RIK GM16348 GM37206 TTLL10 1810017P11RIK AI838599 DUSP15 GM12940 BC037034 A330023F24RIK 1810017P11RIK AI838599 DUSP15 GM12940 BC037034 A330023F24RIK AI480526 GM43597 MAPK15 MAPK1IP1 GM42979 9330151L19RIK TRIM3 TTC41 AC154347.1 AU020206 MIR5125 KRBA1 AC160637.1 DLG5 KCNT1 SBSN ZFP512B TRIM39 8430422M14RIK TBX3OS1 ZKSCAN7 SUPT20 D630044L22RIK GM45632 BC024386 TMEM44 PPP2R3D ZFP462 GM17193 INSRR AC160405.2 ANKRD24 1700034H15RIK A730017L22RIK GM20605 MAP3K12 4930426D05RIK AC147634.1 4833420G17RIK 4933427D14RIK CRAMP1L A430105I19RIK POT1B D930015E06RIK ZFP865 GM13563 1700029J07RIK A430110L20RIK GM17491 GM20342 ZFP467 A230050P20RIK ZFP384 ZFP707 TMEM198B GM12992 GM12121 GM43413 4933408B17RIK 0610005C13RIK GM37090 GM45250 GM20100 GM45838 GM37893 PHYHD1 NOVA2 AC079680.3 KLHL20 GM43609 A730011C13RIK CCHCR1 GM11611 Top 500 downregulated genes in mouse kidney with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/ZPnYkqjkJ DCTPP1 UBL5 SLC10A2 TIMM8B ERICH4 TBCA SUMO3 NUDT2 SPINK1 YWHAQ COMT AADAC HIST1H1C TINAG MME MPP5 ANKS4B MIPEP NDUFAF2 XPNPEP2 GTF2F2 TM2D3 STOML2 GRPEL1 HSP90AA1 FAM162A HMOX1 CALM3 CALM1 TUBA1C CTSD TUBA4A SDF2 ABCG2 NDUFB9 RARS HSBP1 NEDD8 ELOB PTGES2 ELOC LNPEP TMBIM4 MRPL35 MDH1 UBE2E1 TM2D2 SCRN3 PSMB1 2210016F16RIK FARS2 TPMT CLDN10 FBXO8 ADH5 FAHD1 YARS2 WDR34 NDUFB6 NXT2 DEFB29 PSMA2 RPS20 TBCB RPL37A UQCR10 NINJ1 FBXO36 CRYM LURAP1L SMPDL3A NDUFB2 RPL30 RPL39 ACOT13 COPS9 RPLP1 RPS14 RPL27A MAL2 PDIA6 CHID1 SNRPB LEPROT TMED9 SRD5A1 CCT5 NDUFB5 PNP MRPL12 POMP SPR AP2S1 DERA ATP6V1F SDHD METTL9 NDUFAF3 PRDX1 NDUFS4 MYDGF PDIA5 NME1 IDH1 OSTC MICU1 PRDX3 LDHA TPI1 PRELID1 PSMB7 BAD MIOX PSMD6 QPRT COX7A1 HSF2BP FABP7 SAMD9L TMED6 RNF7 SPTSSA UQCRB YBX1 AKR1A1 ATP5G3 ATP5J ANAPC13 MRFAP1 NDUFA3 CHCHD2 RPS19 UQCRC2 CYB5A BCAP31 COX7A2 EIF3I SNRPD2 RPL26 CTSH PPIB RPN1 NDUFA13 GABARAP COX8A MRPL20 NDUFS6 PTP4A2 CETN2 ATP5H NDUFB3 NDUFB11 SRP14 DYNLT3 CNBP PSMB4 RPL18A JTB NDUFA2 LAMTOR1 RAN ROMO1 NDUFV3 NDUFC1 CFL1 MPC2 COX6B1 NDUFA1 DNAJB1 CFDP1 VTI1B VPS35 GNG11 NDUFA4 ARL1 MSANTD4 NOP10 NDUFC2 CHCHD1 RPS27L MRPS18C ATP5J2 GLOD4 TMEM256 GPX4 COX14 MIEN1 CACYBP FBXO40 SPP2 GNA14 TMEM258 DPY30 OST4 PIGF ATRAID DPM3 MRPL34 CYB561D2 PDZK1IP1 POLR2G MRPL46 LAMTOR2 ATP6V1C1 TXNDC17 CHMP5 CHCHD4 TMEM205 TMEM208 CUTA PFDN2 PRDX4 CKB AP1S1 MTX2 TMX1 RABAC1 CCDC124 MAGOH COPS5 MRPL42 ORMDL2 PSMD10 SAR1A VMP1 UQCRQ PIH1D1 THYN1 NDUFA12 ATG5 SSR4 FAM96A PCMT1 AMD1 MCEE NIT2 ETHE1 SPCS1 HOXB7 SSR2 MRPL17 HSPE1 NDUFA9 RPL32 RAB1B SF3B5 TOMM5 FKBP4 KRCC1 MEA1 MSMO1 ATP5E MKKS SLIRP TMEM27 APOBEC2 NUDT1 DCPS SNRNP25 BET1 MRPS11 SLC35A1 GINM1 CCDC91 COA7 CSTB RSU1 SEC61B CLIC1 UQCRFS1 UQCR11 SERP1 SARAF COX6C CALM2 UGT3A2 PRDX2 VPS45 TRAPPC1 PFDN1 COPZ1 AASDHPPT SCFD1 RER1 TRAPPC4 GATB COPS3 SEM1 GTF2H5 PET100 RPE SSU72 RNF5 BSG PSMD5 SELENOF UXS1 STX8 SF3B6 SEC22B SPG21 SNX6 FKBP11 FARSB COX16 ZNRD1 FMC1 IFT20 TOMM22 UBA6 SNRNP27 TMX2 WDPCP CMPK1 AURKAIP1 BUD31 COMMD1 ACAT1 COMMD3 CNPY2 COMMD6 CSRP2 MFF PTER THEM4 FAM173A BOLA1 ASNA1 POLE4 NUDT14 MRPL54 NDUFA11 RNASEH2B SELENOK ACOT9 NME6 TRDMT1 PGP ATG10 ORMDL1 FIS1 DERL1 FUNDC1 MRPL40 CPQ GALK2 SLC46A1 SMU1 ACMSD SULT1C2 FAM151A PIN1 PNO1 TIMM50 THAP4 XRCC5 CCNC RPS4X TMED3 RHOC SELENOT SELENOH SELENOM COX7B TMEM70 AK1 RPS3A1 FAM213A DYNLRB1 CHCHD3 MRPL30 TOMM7 COMMD4 NSDHL TRAPPC2L POLR3K CHCHD6 NDUFB8 DGCR6 COMMD2 NAA38 NSMCE1 NDUFS8 TIMM17B YIF1B SNRPD1 ATPIF1 EEF1E1 MRPS14 MRPL57 CENPX UQCC2 COA6 C1GALT1C1 BLOC1S5 CRIPT LY6A OAF LAMTOR4 2310039H08RIK CYP2C69 D8ERTD738E ATP5F1 MRPS16 SPRYD7 BDH2 ELOF1 NUS1 PYCRL TPK1 MINOS1 NCBP1 DPH3 TAF9B PKNOX1 CFAP36 CCDC51 FAM220A MRPS28 PPP6C TIMM22 MRPS24 TMEM222 2810428I15RIK 0610007P14RIK MRPL45 SDHAF1 CHMP6 UBE3A POLR2I SMIM7 NPHP1 TMEM242 MRRF TOR2A TUBB2B LYRM4 NENF RPP21 FASTKD2 MED28 E2F5 TMEM216 MRPL36 NNAT EEF1AKMT1 FBXL4 DLEU7 OARD1 CALML4 MKRN2OS AKR1C21 ZFP35 GM3716 INSC DHRS7B BC004004 BOD1 AKR1C21 ZFP35 GM3716 INSC DHRS7B BC004004 BOD1 1110059E24RIK 0610009B22RIK ATP6V0E ELP5 2010107E04RIK 1810037I17RIK AKR1E1 FAM92A GM9800 1700037C18RIK GM4952 CYP2J5 MFAP1B ARL6 2410015M20RIK BC031181 ADGRG4 HENMT1 TMEM41A FAM45A TMEM167 POLR1D 0610012G03RIK 1110065P20RIK 1500011K16RIK B230118H07RIK CDPF1 PRORSD1 PIGYL TMEM128 AC121965.1 CYP2J11 HPRT BC026585 RPL7L1 NDUFAF8 OLFM3 AFG1L 1110008P14RIK DCDC2A PEX7 GM19541 Top 500 upregulated genes in mouse lung with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/KOjV72sBr SLC36A1 CEP250 CHPF2 CANT1 PIK3R2 IGSF8 SYVN1 EIF3F FBXW5 PCK2 SCAP UBC UPF1 ARRB2 ZC3H18 FURIN FAM109A SPTBN5 VARS HGS ERBB2 BAG6 CRYBB3 BRD4 CRTC3 MOV10 TBKBP1 MARK2 AKAP8L UBQLN2 SCARB1 ATXN2 FBXL6 POLRMT ACBD4 SF1 BRF1 PARD6B CCDC84 LZTS3 PNRC1 SRRT TMEM94 KHSRP C2CD2L SYMPK SLC12A9 IFFO1 OGDH MBD6 GRINA RPS6KA1 PCNX3 LDB1 GIGYF1 CAD PIP5K1C GGA1 CIC ZSWIM8 INF2 RARA TRIM65 SMARCD1 CLUH SNRNP70 NCLN VSIG10L STAC3 PRRT4 ARHGAP23 MIB2 ZFPM1 LLGL2 MYC ZFP36L1 B4GALT3 ABCD4 ZFP36L2 SLC2A8 CISH CNOT3 WHRN NECTIN1 SREBF1 BCL9L PLEKHH3 SCRIB SEMA3F ALS2CL PPP1R13L CAMSAP3 KRT80 PPP1R37 TNK1 NKD1 TCF7L1 LRP5 NFIC ABCA7 TCF7L2 SAFB ATAT1 CCDC9 CUEDC1 MED25 DYRK1B PHF12 ZMYND15 WDTC1 RAB11FIP3 RERE AP2A1 RNF44 TNK2 TMEM63B PHC2 FBRS PITPNM1 MNT RGL2 SCAF1 ULK1 GLTSCR1 ARHGAP27 SETD1B PLPPR2 LRCH4 ATG2A TNRC18 EPN1 PRR12 INCENP SLC25A22 SHANK3 TOX2 YBX3 UNC45B R3HDM2 SMAD6 JUN SH2B1 PABPN1 ADRM1 CAMTA2 TMEM259 VWF FAM160B2 MEGF8 KDM6B MFHAS1 ZC3H12A RGMA DGKQ CCM2L ADAMTS10 MYPN NTNG2 FUS ANO8 PDE4A MAPRE3 SLC25A27 BBC3 IRF2BPL CLCF1 ZBTB34 WBP2 SF3A2 WBP11 NEAT1 LENG8 COL7A1 MARK4 GAS2L1 DLG4 SFSWAP FAM189A1 ADAMTS14 SLC6A9 PIGT RNF31 CRACR2B XRCC1 SNHG11 RASD2 CASC3 SLC25A28 KIFC2 NPR2 CNNM3 UCP2 PROSER3 CARM1 HNRNPL WHAMM PHACTR4 GTPBP2 ACTN1 MAST3 SIRT4 SLC25A42 KLHDC8B GRIK5 NUMBL ALPK3 REXO1 FAM57B CDK9 BCR DOT1L NKX2-1 SPRY1 TGFBRAP1 EEF1A2 RBM22 WIPI1 AP5Z1 CDC42BPB CLN6 CHKB TBC1D17 FAM193B TPCN1 ITFG2 ZFHX2 FLT4 HNRNPD NDOR1 MEF2D HMG20B DUS3L ULK3 PLEKHM1 PLK3 HDAC5 ENG PHLDB1 NCOR2 RNPEPL1 POLR2A ATP13A1 CRTC1 FBRSL1 PCDHGC3 EPHB3 YPEL3 JAK3 MADD HDAC7 PARVB ATP6V0A1 NFATC4 RHBDF1 FARP1 ADCY6 MICAL3 SLC9A1 PLEKHM2 FHOD1 LMBR1L DOCK6 WBP1L FAM214B PRICKLE3 PPARD TRIM62 RNF216 HNF1B VAMP2 SEMA4G SIRT6 ARID1A DOPEY2 SHROOM3 RING1 ABCC10 EHMT2 FOXP4 CBX7 FENDRR PITPNM2 MAPK7 MCOLN1 HSF4 AMBRA1 CPT1B ADAMTSL4 CRTC2 NPAS4 STK11 PRKCG ATP13A2 NOTCH4 DNM2 RPS6KB2 PDCD6IP TECPR1 ABCA2 MTA1 PARP4 PEAR1 PPIF HOXB4 GPSM1 PATZ1 PELP1 DHX37 MLLT1 MMP15 AKNA ARHGEF1 SP2 TEAD3 ACSF2 CTDSPL TIAL1 ATXN2L SCAF4 FOXJ2 GGA3 ARHGAP17 RUSC2 BAHCC1 GSE1 CNKSR3 OSBPL7 HS6ST1 TMEM201 IZUMO4 NFIX FAM43A EIF4EBP2 RASGRP2 PDK2 FBXL19 CASKIN2 INTS1 CPSF1 AARS2 RHOT2 ZMIZ1 CDK18 FAM98C MAP4K2 CCDC61 ZMIZ2 SETD1A TJAP1 UBE2O NCKAP5L ZBTB7A SPACA6 CAPN15 TCHP PPOX RFX1 NDST2 GABBR1 H2-Q4 SIDT2 H2-Q5 PRRC2A SAFB2 PKN1 SBF1 DPYSL5 THAP3 CLASRP GIT1 RRNAD1 IDUA MMP28 ARHGEF17 SEMA6C TNS2 SCUBE1 RNF126 ZC3H3 FAM219A SLC6A8 HOXB5 U2AF1L4 NCDN RGL3 BRD3 SRRM1 INAFM1 PROSER1 ZDHHC8 ADGRL1 DNAJB12 AATK PHF1 TLE2 CABIN1 NAT6 POM121 CLK2 ZFP362 E4F1 TSC22D4 PHF2 WIZ RIN1 UNK WNK4 ANKRD63 ATN1 HDGFRP2 KCNC3 CCDC97 CC2D1A LLGL1 SART1 DCTN1 PTPN23 MINK1 PRPF40B IQSEC2 EML3 DLGAP4 SAMD4B CHERP ACRBP ZBED3 MAMDC4 PCSK4 ZFP579 SULT5A1 GNAO1 TMEM191C TAF4 SLX1B PCGF2 CCNK MIER2 ARHGAP33 IQSEC1 AP1G2 NRBP2 KMT5C DTX3 PLEKHG4 PRRT1 DENND6B BAIAP3 BAHD1 SLC9A5 NEURL2 AFF3 ATXN7L2 EXOC3L2 4933439C10RIK CBFA2T3 RGS11 ZFP219 ZNRF1 GM44597 ZFP319 ZKSCAN17 ADAMTSL5 AI480526 GM36266 AC163040.2 ZER1 MIR5125 WIPF2 ZFP598 NPFF TBX6 8430422M14RIK GTF3C2 FAM65A PPP2R3D AC160405.2 ZFP865 GM17491 A230050P20RIK GM37090 PRR3 TRERF1 WIPF3 ZFP408 ZFP523 XNDC1 ZFP653 AI837181 LTB4R1 ZFP574 5031434O11RIK ZFP395 GM16295 LRTM2 ZFP553 ZFP641 1700017B05RIK GM44246 A530020G20RIK ZFP628 Top 500 downregulated genes in mouse lung with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/KOjV72sBr DPP4 HSPA5 VCAM1 DDX10 SNX1 ITGB1 EIF2S1 MME COPB1 ATP6V1A TLR4 TMEM97 SCCPDH GTF2F2 ADAM9 HSP90AA1 LARP7 CTNNB1 NCK1 POLA1 ENPEP HEPH COPB2 AOC1 TARS CRK CANX AASS CHP2 SLC30A7 INTS4 PES1 STOM PLS3 HSPA8 PAICS MYNN NR3C1 SCP2 ARSK ARHGAP18 SIAE ADK POLR2B BPIFB1 SLITRK6 CP SDC1 RGS2 REPS2 SCGB3A1 MT-CO1 CFH CCDC80 PTGFR SLX4IP SEMA3A POF1B INPP4B CCL8 AIF1 PRNP STT3A PDIA6 C1QC ENPP4 CHID1 C1QA PDIA4 CCT5 PNP MACC1 SCARB2 CTSB MGST1 SEC23B SLC1A3 C1QB CCT8 HGF TMEM45A CCR2 DPYD MMP19 PRDX3 SPATS2L LDHA TPI1 PSMB7 SGCD ENPP5 ST8SIA6 BMPR1A AZIN1 STK3 COL5A2 ABCE1 IMPA1 COL14A1 TMOD3 LRRC8E SPARCL1 MMP3 NUCB2 IRF4 UMPS COLEC12 SMC2 MAD2L1 MASTL ADIPOQ BPIFA1 RETN CFD ENPP6 CCL17 GBP4 FOLR2 IFIT2 HEPACAM2 VCAN GBP2 SAMD9L TLR3 GLT8D2 ITGA8 ATP13A4 DGKB NEGR1 SCN3A C1QTNF3 SCN7A GSTM5 MORF4L2 OGN LAMP2 DPT MYH10 SERPINB9 DDR2 CETN2 DYNLT3 CCT3 BLMH DSTN ANXA1 TVP23B CFDP1 VPS35 MSANTD4 CETN3 CD36 WDR45B OAT SSR3 ACADSB CNTN1 CACYBP PI15 ART4 SRPX KCNE4 BMP5 LRRK2 PLA2R1 MAGT1 MOB1A HAT1 GTF2E1 TMEM33 ATP6V1E1 CHMP5 PJA2 HSP90B1 PSMD10 SUCLA2 SDC2 SAR1A ATG5 GJA1 BUB3 BZW1 VAMP7 SLC39A10 SNX4 ST13 HDHD2 MMGT1 EPRS NAA20 NARS EPHA7 SEC23A DNAJB4 GPBP1 NCOA4 CKAP5 PTPRD CSE1L ZMPSTE24 NEDD1 ASNS CREM SPPL2A ASCC3 TMEM252 F13A1 TFF2 TFRC PDGFRL RP2 OTUD6B PTGR2 STX19 C6 CFI VPS41 LAMP3 SEMA3E PRPS2 RPL22L1 TTC3 APPL1 DNAJC3 CCDC91 CD83 CCDC47 NOSTRIN NUDCD1 RSU1 CALM2 ACTR2 FLRT2 CDH13 HSPA1B ITGA6 HC GOSR2 COPZ1 SCFD1 SUGT1 ANAPC10 PEX2 ADGRE1 DARS POSTN GTF3C3 GNAI3 YIPF1 APMAP COPG2 SNX6 COPA FARSB PLRG1 FAM32A RNF13 UBA6 ZDHHC13 SLC35F5 GALNT1 MCFD2 ALDH3A2 ASAH1 CAPZA1 ACKR3 CCT6A ANXA4 CHMP3 STBD1 TRMT2B RCBTB2 SLC10A7 ERAP1 SMIM3 TMEM123 P4HA1 DHX29 PLA2G4A PPAT HNRNPC ACP2 UTP6 PSMD2 FXYD6 COG6 SMAD2 RNASEH2B FAM91A1 GMFB EXOC3 ROBO2 SLC26A3 LIG4 TEX15 GOLM1 LPP LIN7C RDH11 FXR1 TRIQK TMEM168 EIF5A2 SLC9A9 TFPI PAK1 PRKDC GOLPH3L LUM VPS50 IL13RA1 RFC1 HACD4 RAB7B LEP STAM2 EXOC4 POGLUT1 SMU1 HTR2A RNF4 S100B CALU RCN1 GCSAM CCNG1 PNO1 SKIV2L2 NUP205 WDR92 XRCC5 CASP12 RPS4X CXCL15 SDCBP DSE PDHA1 SMC1A METAP2 MFSD14B MAOB CHCHD6 FEZ1 MANBA DZIP3 PGAP1 KLHL13 TUSC3 PPP1R3C MFAP3 CRNKL1 CD109 TES ECM2 QPCT HSPA13 LIMS1 RRP15 RAB27B EMB GOLIM4 DYNC2LI1 MRPL50 RBBP9 C1GALT1C1 ECHDC1 SEMA3D OXCT1 GBP9 C1S1 VWA5A MS4A6C SERPINA3N CAR3 7-SEP ADH1 SCD1 EDA2R ARMCX3 PHKB PDCL RPS6KA6 DNAJC10 CXADR TTC33 ENSA ZHX1 GSAP SCAPER NHLRC2 DCTN4 TAF9B CHM NIFK CCSER2 CD59B CES2G RAD50 WDR61 EIF1AX AU021092 0610007P14RIK GGTA1 DYNC1I2 COA5 FAR1 UBE2W SLC2A13 TWSG1 LYNX1 COPS2 ATAD1 SKAP2 MR1 MTMR6 NIPA1 EIF2S2 FER DLD 10-SEP KLHL9 LPAR1 CDKL5 ITGBL1 USP46 RNGTT TTC27 TRMT5 FAM175B COG5 KLHL7 NNAT PHEX FREM1 TMTC4 ZFYVE16 MGL2 4930578C19RIK ABCA8B ZFP35 KBTBD4 ST6GALNAC3 ZFP35 KBTBD4 ST6GALNAC3 1110059E24RIK INTS2 ZFP260 LYZ1 PCDHB16 AKR1E1 3830406C13RIK TMEM167 B230118H07RIK CDKAL1 PCDHB7 CHIL1 9230104L09RIK ARF2 F8 CAPN6 AC153958.1 ZFP712 KCNE2 3632451O06RIK TCAF2 CNTN4 AC153368.1 ZFP146 PCDHB8 SKP1A ISPD ENOX2 ZFP518A GUCY1B3 PCDHB13 TGOLN1 CKMT1 OLFR1033 CYP2J6 UBE3C D3ERTD254E GM6472 ZFP790 IGSF10 FCRLS PCDHB14 SYTL4 GM15501 AW112010 PCDHB19 4930486L24RIK H60C ADAM5 OIT1 1810011O10RIK KLRA4 PCDHB22 D6WSU163E GM830 PDXDC1 GM17473 1110012L19RIK Top 500 upregulated genes in mouse spleen with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/4BVc9vATW SLC36A1 CEP250 CHPF2 CANT1 PIK3R2 LARP1 GMIP SLC27A2 MAP7D1 UPF1 MAST4 ZC3H18 PRRC2B FURIN FBXL12 ANXA11 NUCB1 VARS FMNL1 BAG6 WFS1 BRD4 SLC23A1 MOV10 AKAP8L SCARB1 KALRN DHTKD1 SFXN5 ATXN2 ATAD3A TMEM80 SF1 BRF1 MYO10 LZTS3 FNIP2 AGAP1 SRRT TMEM94 SYMPK SLC12A9 IFFO1 ANKRD52 TAOK2 PIEZO1 MBD6 MAPK8IP3 INPPL1 ZC3H7B PNPLA6 PCNX3 HDAC6 GIGYF1 CAD KHNYN PIP5K1C GGA1 CIC LRP1 ZSWIM8 INF2 RARA TRIM65 SMARCD1 CLUH SLC6A6 ZYX NCLN PLEKHN1 TRPM2 SORT1 TNRC6C RUNX3 PTPRS PBXIP1 B4GALT5 NOTCH1 VPS9D1 ABCD4 TRAK1 PKD1 CISH CNOT3 WHRN AGRN CELSR1 BCL9L TMC4 CEP170B SCRIB SSH3 BCL9 SLC4A2 TCF7L1 LRP5 NFIC TCF7L2 SAFB CACNA1H ATAT1 CCDC9 IQCE MED25 DYRK1B TECPR2 PHF12 ZMYND15 NBEAL2 KMT2B RERE AP2A1 RNF44 PICK1 TNK2 TMEM63B FBRS PITPNM1 MNT RBM47 SCAF1 PLEKHG3 ULK1 GLTSCR1 ARHGAP27 SBNO2 SETD1B MIDN LRCH4 ATG2A TNRC18 PRR12 DENND1C CCDC88B FCHO1 PREX1 NLRC3 SLC25A22 HAP1 UBA7 TTYH3 SHANK3 ATP6V0C R3HDM2 SH2B1 PSMD3 PABPN1 CDK16 PLEKHG2 ADRM1 CAMTA2 CSF2RA FAM160B2 MEGF8 USHBP1 KDM6B ZC3H12A DGKQ ADAMTS10 PRDM9 SYNGAP1 RIMS3 NTNG2 MRI1 FUS ANO8 CMIP PDE4A SEC31B MAPRE3 BRD1 ZNFX1 ZBTB34 ACIN1 SF3A2 SPRED3 TOB2 PAN2 DQX1 NEAT1 LENG8 AOC2 MARK4 TRIM41 ADAMTS14 LMTK3 PIGT EXTL3 NLGN2 RNF31 CDC42BPG SLC43A2 CASC3 KIFC2 TULP4 UCP2 IGF1R CARM1 TM6SF1 SRRM2 PRRC1 GTPBP2 TRIM26 NAV1 MAST3 SLC25A42 SESN2 DNM1 FANCA GRIK5 REXO1 IRAK1 ZDHHC1 DOT1L SPEN FAAH CELSR2 RAB4B ATG9A ELL ARAF RBM22 NUDT8 AP5Z1 CDC42BPB FAM193B TPCN1 MAN2C1 USP36 ZFHX2 NDOR1 MEF2D HMG20B TEP1 DUS3L ULK3 UNKL PACS2 NCOR2 RNPEPL1 CRTC1 TET3 FBRSL1 PCDHGC3 CACNA1A JAK3 PLXND1 RHBDF1 MICAL3 GNL1 PLEKHM2 NISCH SASH1 FHOD1 DOCK6 HIPK2 WBP1L ATP6V1G2 PRICKLE3 PPARD WASL ZFHX3 SLC12A3 VAMP2 ABI3 DGKI RREB1 ARID1A KMT2A SIPA1L3 DOPEY2 ABCC10 DNMT3A EHMT2 CBX7 PITPNM2 SRGAP2 ZFP609 MAPK7 MCOLN1 PROX1 WDFY3 CRTC2 UBR4 RPS6KB2 TECPR1 NOD1 SEMA4A ABCA2 MTA1 IMPDH1 PEAR1 LIMK1 ERN1 GPSM1 PELP1 LATS2 LTK ARHGEF1 MAP2K7 ACSF2 ATXN2L SCAF4 IGHMBP2 TBC1D22B FOXJ2 GMEB2 NEURL4 SIK3 GGA3 RNF111 BAHCC1 KIF21B GSE1 HS6ST1 TMEM201 NFIX MTSS1L CCDC6 EIF4EBP2 CASKIN2 GTF3C1 INTS1 CPSF1 ZMIZ1 SZT2 RAD54L2 MOSPD3 MAP4K2 ZMIZ2 LMF2 SETD1A SUGP2 NCKAP5L SPACA6 RAI1 CAPN15 FBXL18 KMT2D FBXL20 USP20 EIF4G3 CUL9 GABBR1 TTC28 KIF1C MGST2 H2-Q7 LDHD H2-Q5 PRRC2A SAFB2 PKN1 SBF1 MICALL1 CLASRP GIT1 MLLT6 USP35 CIZ1 IDUA DOCK4 GAN ACACB FAM219A U2AF1L4 SRRM1 ARHGEF40 PROSER1 ADGRL1 ARHGAP39 ARMC5 ALDH5A1 TPCN2 TLE2 CHD7 POM121 POU6F1 CLK2 MKL1 ZFP362 ZFP385A PHF2 WIZ UNK MKS1 PPP1R12B KCNC3 CCDC97 CC2D1A CROCC MED15 PTPN23 MINK1 PRPF40B IQSEC2 YLPM1 SNAPC4 MEIS3 HABP4 DLGAP4 PALM CHERP CNTNAP1 ATXN7 ZBED3 MAMDC4 PRDM11 AW011738 ARHGAP27OS3 GDAP10 GM43858 CPSF7 PCGF2 STK35 MIER2 PITPNM3 PLEKHG5 CRACR2A MAPKBP1 HOXB3 DTX3 CHST12 DENND6B SNED1 SLC9A5 ATXN7L2 CARMN ADAM11 9330175E14RIK 2900026A02RIK PPP4R1L-PS LYRM9 TRP53I11 DVL3 GM44597 ZKSCAN17 GM37206 BC024978 AI480526 GM36266 GM37019 GM43375 GM25747 ZER1 WIPF2 ZFP598 ZFP335 AC124556.1 FLT3L ZFP512B FAM65A CRAMP1L A430105I19RIK ZFP865 ZFP467 A230050P20RIK GM37893 ZFP523 5031434O11RIK ZFP395 ZFP553 1700017B05RIK GM44735 C230037L18RIK AC126804.2 2010016I18RIK GM33280 GM14226 GM45867 MYPOPOS GM43857 GM37261 GM44861 4930518I15RIK MIRT1 GRK3 GM16008 SLIT1 CEACAM16 AC160405.1 ADAM33 AC133083.4 LDLRAP1 GM2065 5430405H02RIK GM22175 MAN2A2 NAIP5 AC126459.2 BC017158 TTBK1 GM45606 ADGRB1 GM37795 GM21781 ZFP827 GM44423 GM44659 CARMIL2 Top 500 downregulated genes in mouse spleen with SARS-CoV-2 infection (Day 7) from GEO GSE162113 Bulk RNA-seq was used to study expression changes due to SARS-CoV-2 infection in mouse organs. GEO Contributors: Li S, Ma F, Pellegrini M, Deb A; Title: Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. GEO Accession: GSE162113. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/4BVc9vATW CD79B MPHOSPH10 RAB2A HSPA5 SH3BGR DDX10 YWHAQ SNX1 YWHAZ VPREB3 CXCL16 TPM4 RALA CWC27 NDUFAF2 ANXA2 GTF2F2 GNG5 GRPEL1 LARP7 FAM162A CALM1 BZW2 COPB2 PSMC6 TARS CANX HSBP1 EIF4E NEDD8 NPM1 PES1 UAP1 ELOC PAICS MDH1 ASF1A PSMB1 NSMCE4A FARS2 ADH5 SCP2 ADK PSMA2 RPS20 BTF3 ENO1 PFDN5 POLR2B TBCB NDUFA10 RPS26 RPL35A RGS2 RPL14 RPL41 RPS15A RPS24 RPL37 RPS8 RPL30 SLC25A4 RPL23 RPS15 RPL39 BEND5 AIF1 COPS9 RPL7 BANF1 PDIA6 SNRPB TMED9 CCT5 NDUFB5 TWF2 HADHA HVCN1 POMP SEC11A SEC23B MTCH2 AP2S1 LGALS1 ANXA5 ATP6V1F SDHD PRDX1 NDUFS4 CCT8 NME1 PSMB2 LDHA PSMB7 MANF IMPA1 EEF1D CLU TMSB4X TMEM60 HNRNPK UMPS CD3G CD3D PTPRCAP ARHGDIB RNF7 SPTSSA TSPAN13 RPL8 TMA7 HMGN1 PSMB10 PEBP1 SPARC SYF2 ANAPC13 MORF4L2 DAZAP2 SH3BGRL FABP5 COX7A2L RPLP0 RPS19 UQCRC2 S100A4 BCAP31 COX7A2 CRIP1 EIF3I CCT2 EEF1B2 RPS5 RPS21 EIF3K PPIB NDUFA13 RPL4 PSMB6 PSMC2 ARPC3 DNAJC8 MRPL20 ABRACL QDPR PAIP2 MATR3 CCT4 CETN2 ATP5H BRK1 SRP14 DYNLT3 SMIM15 CNBP RPL15 NDUFA5 PSMB4 NDUFA2 CCT3 HN1 CFL1 ARF1 CDIPT BLMH COX6B1 NDUFA1 CAPZA2 GM2A VTI1B VPS35 RPS3 NDUFA4 NDUFV2 NOP10 CETN3 SUB1 GTF2B EMC2 SET DBI RPS27L MRPS18C OAT SSR3 S100A10 ATP5J2 GLOD4 ATP5C1 CD9 S100A13 MIEN1 DAD1 EIF3C SAMSN1 SERPINI1 DAPL1 CYTIP SERTAD1 SNRPG POLR2G MRPL46 PSMA4 VAMP3 GTF2E1 ASNSD1 TMEM33 TXNDC17 CHMP5 CHCHD4 ARL6IP5 SARNP BRE TAF12 DDX18 MRPL13 TTC1 MAGOH COPS5 NHP2 PSMD10 SUCLA2 EBNA1BP2 ARFIP1 GMPR2 SAR1A NOP58 EMG1 MRPS23 POLR2E TAF13 VRK1 SLC25A5 ATG5 SSB BUB3 APEX1 PSMA1 BZW1 UQCRH GTF3C6 ST13 EPRS TUBB6 EBPL NDUFA9 SNRPE RPL32 RPL34 IER3IP1 TCP1 GPBP1 PTBP3 SF3A3 ARL6IP1 CNN1 KRCC1 TAF7 MEA1 TXNDC16 MAGOHB RPA3 TRA2B NUP43 GPR183 GPR18 RHOH HNRNPF SEC62 RPL22L1 TWISTNB ESCO1 CD83 NUDCD1 RSU1 MYL9 CD53 SMARCE1 SNRPB2 CALM2 P2RY10 ACTA2 SPRYD4 ENPP2 PSMC4 WDR82 PFDN1 COPZ1 THUMPD1 SNRPD3 POLR2H SCFD1 YEATS4 RER1 SEC13 SUGT1 TRAPPC4 PFDN4 SEM1 GTF2H5 SFR1 PPIE KARS ESD SELENOF TSN RABIF GNAI3 SF3B6 HMOX2 SNX6 FARSB TNFAIP8 PSMC5 PLRG1 SNW1 TOMM22 PIK3C3 ATG12 RNF13 SUCLG1 TMEM9B FUNDC2 ATP6V1H CDC42 CMPK1 BUD31 COMMD1 BST1 CCT6A ANXA4 CHMP3 CIAO1 CSRP2 DEGS1 CTNNBL1 NIP7 DCAF13 PTCD2 RPF1 CEBPZ WDR75 RIOK1 PPAT TSR1 NDUFA11 COG6 PUM3 SELENOK SPCS3 ADSS SNX2 BFSP2 NAT2 FAM3C RDH11 FXR1 R3HCC1L EFL1 ORMDL1 DERL1 FIG4 GOLPH3L CNOT2 CD79A UBR7 SMU1 PHF6 CALU RCN1 DNAJC15 PNO1 WDR3 UTP3 ORC5 ZC3HC1 RAD17 XRCC5 NOLC1 RPS4X PDHA1 LYZ2 H2-AA RPS3A1 CEBPZOS IMP3 HSD17B12 OCIAD1 EIF3L TOMM7 TNPO3 GTPBP4 SRFBP1 EIF2B1 EBP MRPS21 PGAP1 KLHL13 STK17B TES RSL24D1 UFSP2 TRMT10C SACS PBDC1 GPATCH4 RRP15 ARPP19 NSMCE1 NDUFS8 PPP1R11 MRPL21 NEK1 MAK16 INTS12 MRPS14 ZCCHC17 NOP16 UQCC2 TMCO1 MRPL50 BTNL9 ERGIC2 FANCL ATP5K LAMTOR4 7-SEP SUPT16 EIF3M GIMAP6 ATP5F1 MRPS16 SERBP1 DPH3 FTSJ3 NIFK IMP4 PRPF31 ATP5O LSM8 EIF1AX PPP6C MRPL45 TEC BCL2A1A CRCP ABT1 DYNC1I2 EAPP FAR1 UBE2W MED11 COPS2 ATAD1 SMIM7 DLD PAK1IP1 RFTN2 RNGTT TTC27 INO80C FASTKD2 MRPL49 TMEM261 MRPS31 RPUSD4 MED30 MRPL58 RRP8 NDC1 BBS9 ZFP638 LYZ1 SNAPC5 2010107E04RIK MFAP1B 2410015M20RIK BC031181 AC121965.1 HPRT SKP1A GIMAP9 GM6030 RPSA-PS11 GM9625 CSTF2T GM13340 2610008E11RIK RSL1D1 NSG2 SERPINB1A BCL2A1D RPS3A3 ZFP330 KRR1 ZFP87 RPL14-PS1 AI467606 ZFP472 KLK1B27 Top 500 upregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (WT, 8 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sZqtLOmuF DCTPP1 ADAMTS1 UHRF1 RBL1 HYOU1 EGR1 MALL CHPF MAP7D1 KPNA2 YWHAZ DDX21 CCND3 HEATR3 TPM4 TPM3 TMEM97 COLGALT1 PKM ANXA2 ST14 FURIN ETV4 NCL SIGMAR1 CIT SLC27A4 DNMT1 TUBA1C FAM98A TUBA4A HIST1H4A SFN PTPRH PLAT MSN ETV5 THOP1 DIAPH1 PTGES2 REN SCARB1 PAICS PLP2 ATAD3A METTL8 LRRC8A ENO1 MT2A KRT18 SLC16A9 AK4 KRT7 HIST1H2AL KRT4 LSM12 KRT17 AQP5 HIST1H4I UPK1B C6ORF132 SPRR1A TFF1 TRIM7 S100A2 KRT8 EMP2 CCND1 SPRR1B TAGLN2 ITPK1 UNC93B1 NACC1 AQP3 TOMM40 VASP FLNA PCNX3 SNRPB LMNA INF2 TRIM65 EMP3 ARHGDIA RHBDD2 ACLY ZYX NCLN PLK1 TIMP1 DHCR24 MYBL2 TICRR CCNA2 CLSPN TK1 CAPG LMNB1 TUBG1 NLN AURKB LDLR HMMR FKBP5 MCM2 CDC25A FADS1 CDC6 E2F1 ORC1 KIFC1 SAPCD2 MCM10 GSTO1 NME1 TPX2 DUSP7 CEP55 KIF23 PKMYT1 MKI67 LDHA CDC45 KIF20A DTL SCD BEGAIN CRIP2 TPM2 LGR6 CRYBG2 CAMP B4GALT2 KLF13 MANF ABCE1 PKP3 ACTB HMGA1 LAD1 GJB3 SREBF1 FGFBP1 PSMD6 ANXA8 SCNN1A LSR ANXA8L1 SLC52A2 SPDEF HR WNT4 FPGS MED25 EPN1 ERF CENPN HIST1H2AJ CCNA1 CREG2 CHEK1 GINS2 DUSP2 FAM83D MCM5 AUNIP HIST1H2AE ZWILCH H2AFX COTL1 SYT12 LRP8 POLE2 GINS1 CHAF1A CCNE2 MDFI TGM1 ALDH1B1 IGFBP6 TNFRSF12A LIPG PFN1 ZFP36 CYR61 IER2 LRFN4 IER3 HNRNPM TUBA1B FOS ACTG1 DUSP1 HMGCS1 HIST1H2BI JUNB JUN ACAT2 EIF5A TUBB SH3BGRL3 EFNB1 ADRM1 ROMO1 S100A16 CFL1 TUBB2A RBM3 ANXA1 FASN EFHD2 PHLDB2 SRSF3 FSCN1 S100A10 CD151 RRAD TGFB1I1 OTOP3 SLC35E4 MRC2 USH1G RTN4R SORBS3 TP53INP2 DUSP5 ZNF367 FOSB PPRC1 UBE2S GYS1 TXNDC17 HSP90B1 SRM PGAM1 CKB PA2G4 PSME3 SEH1L LSM7 NOP58 UCHL3 DKC1 AMD1 RFC4 NAA50 PSMA7 PPP3CA GMNN TUBB6 TMSB10 C1ORF122 CDC25B ODC1 HIST1H2BE HIST1H3G GOT2 RANGAP1 SRSF2 NOP14 HIST2H2AA3 HIST1H1A HYAL1 INSIG1 GAS2L1 MSMO1 HMGCR SQLE DPH2 CSE1L CEMIP MCM6 MVD HIST1H3B SLIRP GMDS VRK2 FEN1 ANXA10 PNPLA3 ELOVL6 PTMS ACTN4 RARRES2 PCSK9 HIST1H3H HIST1H4D HIST1H2BL APCDD1 MCM4 MCM7 PHACTR3 WDHD1 ALYREF PLEKHA6 LMNB2 STARD4 CHAC2 PPIL1 HNRNPA2B1 RPL22L1 GBP1 CKAP4 GJB2 EIF5B BOP1 ACOT7 MLF2 EMP1 HIST1H2BO PRSS3 RHBDF2 NMU BRI3BP CA9 ACTN1 COPE HNRNPA1 CD44 HIST1H2BF GAS1 HEYL PDLIM2 KRT6B BCAR3 PHLDA2 SERPINB8 NEK6 FADS2 NR4A1 KRT6C KRT6A ANO1 HIST1H3J LINC00707 CD68 FANCA SLC13A5 ITGA6 IRAK1 GLRX3 FTSJ1 IDI1 PRMT1 MAP4K4 HIST1H1B MRPS12 GNPNAT1 FARSB TPM1 SUV39H2 PLEK2 PDIA3 TBL3 PRKAR1B CLTB LSS MVK PCDHGC3 MFSD12 ACSL1 ANKRD22 KLK10 E2F4 PLXND1 PPP1R14B ATP6V0A2 LETM1 CTPS1 C19ORF48 FDPS RPS6KA4 FDFT1 PC SPCS3 ELN SREBF2 CPA4 GAS7 GTF3A HIST1H3A SERPINB13 SRPK1 RDH11 GALNT6 PGP GPC1 RAET1E LRRC59 HIST1H2BJ ATP13A2 PGAM5 PSMG1 PTBP1 CYP51A1 MRPS26 NAA15 LIMK1 MCM3 CHD1L MRTO4 MCMBP MYBBP1A HNRNPAB NUP188 RRS1 IFRD2 GRWD1 NOLC1 CS EHD2 BCL7C NOL6 DHCR7 NSDHL MMAB SLC25A1 EBP GMPPB MICAL2 MFSD2A TRIM47 IGFL1 CD109 NGEF TMEM104 ZMIZ1 DDIAS PBDC1 GPATCH4 CAVIN1 BOK GALE JPT1 9-SEP DESI1 PFKP CAVIN3 C11ORF24 PADI1 PALLD LPAR5 CAPN15 ERG28 NOP16 PDCD5 HNRNPR PIMREG HIST1H2BB SLC25A13 HIST1H3F HIST1H3C HIST1H2BM HIST1H2AH HIST1H2AI PDLIM7 ATP5F1D PCDH19 MMP28 SOX8 NGFR SLC6A8 FAM213B ZDHHC14 NSUN2 RIN1 HEY2 ADCY3 SYNC MAPK1IP1L TUBB2B PGAM4 RUSC1 HIST2H3D NDC1 KCNQ5 P3H2 C1QTNF12 ADAMTSL5 LZTS1 HIST2H2AA4 SARS_COV2_ORF3A SYT5 SARS_COV2_ORF1AB SARS_COV2_ORF8 HNRNPA1L2 WDR76 FAM86C1 BX255925.3 AL450992.2 AC126365.1 PYCR3 RNU1-122P IL12RB2 LGALS7 HIST2H3C HES5 HIST2H3A SARS_COV2_S PLA2G3 Top 500 downregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (WT, 8 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/sZqtLOmuF SEC16B GDF15 UGT1A7 SQSTM1 PCK2 COL4A5 SLC7A7 PGLYRP4 ATXN3 LYN SARS GGT1 SLC46A3 HMOX1 CEP68 ATM ING4 NCKAP5 TARS NR3C2 CLIP4 ABCG2 HERPUD1 MGAM EPHX2 STC2 WFDC5 ZC3H12C PCMTD2 ADHFE1 VPS13B SIAE ZKSCAN1 CPT1A CACNB4 GPR155 RPS6KA5 N4BP2L2 BCL2 NBEA PCP4L1 MECOM TSHZ2 LINC01133 TNFSF10 CFTR OLFML2B RARB CGNL1 SLC40A1 FGFR2 MTRNR2L8 LURAP1L CA8 PNRC1 COLCA1 RASSF6 MTRNR2L12 KIAA1324 ADH1C FNIP2 TCP11L2 PLCB4 BCAS1 SNORA73B ADH7 KRT15 SIX4 ANK3 ABCA1 ZBTB20 FTL TTC14 RNASEL ACSS1 TGFBI SLC1A5 PYCR1 ALDH1L2 KCNE1 ITGA7 BCAT1 GRB10 DPYD MMP19 MTHFD2 CA11 TNRC6C PBXIP1 ZNF266 HINT3 MARS KLF15 COL5A2 SLC2A5 PIK3IP1 MYCL FAM84B BCAS3 SPARCL1 KITLG INPP5D ANKRD6 WNT5A ATF3 GABARAPL1 NUCB2 MAP2K6 PAX6 ZCWPW1 DACT2 TRPV6 ZNF862 GATM CD27 ULBP1 CLEC7A TXLNB PSAT1 CHL1 CH25H APOL6 C1R STAT2 UBA7 ATP13A4 SVOPL CLIC4 PCBP2 MAP1LC3B FMO1 PXDC1 SEMA3C ALDH1A1 NR1D2 NUPR1 DDR2 BNIP3 DDX17 PEX6 ATF4 JDP2 MYLIP TMEM260 EIF4A2 IVNS1ABP DDIT3 NOS2 TAGLN3 RAB30 TRIM22 ERMAP HMCN1 TMEM150C INSR ZFP14 FBXL19-AS1 DLX4 PLA2R1 BAMBI ZSWIM6 CHAC1 YPEL5 ARMCX2 DHX40 EPRS BEX2 FOLR1 DDB2 MXI1 DNAJA4 RSRP1 CADPS2 MKRN1 TMEM47 ZNF512 DQX1 TNFSF15 FOXO4 VEGFB CREBRF TTC21B IP6K3 KLHL24 DENND5A REL SLC6A9 CIITA ATP10B ASNS DNASE2 PPM1K SELL DLL1 POU2AF1 SLC1A4 TFRC ALDH3A1 AARS GPRASP1 TESK2 LINC00324 CCDC28A VPS41 HHAT NBPF11 TIA1 TRANK1 GARS PPP1R9A XPOT FNIP1 CEP290 TM6SF1 SLC25A36 GPT2 PMAIP1 SLC28A3 PMM1 BTN3A1 C1S TRIM38 PXK PIK3AP1 ALDH2 EIF1 CDKN1B PUM2 ADD3 RGS17 IGIP KCNE3 VLDLR-AS1 CBS SESN2 LMCD1 CLK1 BACH1 FRMPD2 TRAPPC5 RIT1 GK LARS CARS KIT YARS CTSF FAM111A ERP29 HTATIP2 GGT2 PHGDH SULF1 SLC35F5 AIG1 CALCOCO1 ALDH3A2 CCPG1 ACKR3 CSRP2 CARD8 RCBTB2 C14ORF132 ZNF680 KCTD7 PGPEP1 MATN2 ALPK1 NFATC4 HBP1 DKK3 ZNF160 XPC SREK1 FAM219B LRIG1 RPS6KA2 MCCC1 ACSM3 STEAP2 SENP7 EYA2 CDK19 CHD6 IMMP2L CCNG2 CBX7 ZFAS1 BCL2L11 SLC9A9 TP53BP1 ZFYVE1 ATG14 ZFAND5 FBXO32 PRR5L VPS16 RAB26 ZNF75D ZNF224 USP49 DNAH5 ABCA5 MPP2 ABTB1 WDR48 EXOC4 ADH1B TRO UGT2A1 TGIF1 RCN1 WSB1 LNX1 IL11RA SHMT2 HRK TOP1MT VPS8 CAVIN2 GPX8 DTNA PLCG2 ETFDH FMO4 ACSF2 HECA NAALADL2 KIAA1147 SEL1L3 TUBE1 KIF21B TTC39B ADM2 AIF1L LOXL4 MANBA SEMA6D TBC1D5 PGAP1 CPE LMBRD2 KCNH1 ECM2 RSL24D1 CEBPG IFRD1 JMY C1QTNF6 FBXO34 KIAA0232 OPHN1 ABHD14B DNAJC4 DHRS3 DCAF11 ANKRD10 ZNF84 PLPP3 ZNF248 TBC1D32 RIPOR3 ATP6V1E2 SNORA49 MIR3609 SNORA73A MACROD2 TBC1D16 GPALPP1 EBLN3P SNTB1 RETREG1 TTC28 SYNPO2 LDHD SLC7A2 EDA2R SNORA28 ZNF555 PHKB PHYKPL PCMTD1 PPIP5K2 WDR19 ADGRL3 ACACB SLIT3 RN7SK RALGPS1 TBCK CLYBL COLCA2 FAXDC2 YPEL2 CLK3 FOXN3 KIAA1109 PHF1 INPP5B RORA MBTD1 DGLUCY COA5 MPPED2 GNG7 MR1 GPRC5B PREPL FAAH2 EIF2S2 ZNF419 TTC37 C2CD5 ME3 GUCY1A2 TCEA3 RCBTB1 RAPGEF5 ZNF483 C3ORF18 FBXO44 PCED1A ARHGAP20 CECR2 AMY2B HEMK1 CNTNAP3B MAGED4B PLXDC1 CBSL ZNF117 ZNF300 SCG2 MPPE1 AKTIP PLEKHG4 CACHD1 NWD1 MFAP2 RHBDL1 PPIP5K1 PYROXD2 ELMOD3 ADGRF5 F8 AC124312.3 C20ORF204 MAGED4 CYYR1-AS1 ZNF577 C1ORF147 RAD51B GTF2IRD2 ZNF345 BHLHB9 ADNP-AS1 AL121895.1 KHDC4 AC009123.1 LINC00365 ZNF460-AS1 AP002026.1 AC245100.6 C21ORF62-AS1 AC136475.1 AP000866.1 GTF2IRD2B AL357033.4 SNORD49A LINC01814 AL356488.2 SMIM10L2A SCARNA9 TTLL9 HEXDC PCAT1 POC1B-AS1 CFAP69 CERS4 AC026785.2 ZBTB26 ZNF354C ZNF135 ADGRV1 GMDS-DT AL158071.5 ERVE-1 AL359715.1 AL035563.1 AC008760.1 PARD3B AL390728.6 ALS2CR12 SLC6A16 RIC3 LINC02185 SNORA5A TTN-AS1 LINC00885 SLC24A1 Top 500 upregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Wild Type, 24 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/2QOOqYgsO GPR151 UHRF1 RBL1 EGR1 IRF3 KPNA2 CXCL10 TP53AIP1 GPT TMEM97 ETV1 CENPF ETV4 CIT DNMT1 HIST1H4A BRCA1 FBXW12 PLAT OASL PLB1 ETV5 ISG15 EVL IGSF9 CDK2 PCSK7 FBXL6 WDR24 SERPINB11 HIST1H2BH HIST1H2AL ATP12A KRT4 ECM1 CCDC84 AQP5 HIST1H4I HIST1H2AG TNS4 CFH SPRR1A HIST2H2AB HIST1H2BK ANKRD36C HIST1H4H TFF1 TRIM7 HIST1H1D POLG ANKRD13D NACC1 GSN PCNX3 TYMP CIC EHBP1L1 INF2 NLRP1 PLK1 EXO1 GAS2L3 MYBL2 TOP2A TICRR ZWINT CDCA8 CCNA2 CLSPN TK1 TROAP LMNB1 CCNB2 GTSE1 CDKN3 UBE2C KNL1 AURKB SHCBP1 LDLR KIF18B NUF2 DEPDC1B HMMR SPAG5 BUB1B MCM2 KIF2C KIF14 ASPM AURKA DLGAP5 ESPL1 FADS1 RRM2 CDC6 E2F1 BIRC5 ORC1 KIFC1 KIF4A EPSTI1 SAPCD2 MCM10 KIF15 SMTN FAM72C PRR11 CDCA2 KIF11 BRCA2 TPX2 CCNB1 ANLN NCAPH CEP55 CDCA3 CDC20 KIF23 PKMYT1 SKA1 HJURP TTK MKI67 CDC45 KIF20A DTL SCD MAP3K6 NCAPG BEGAIN CROCC2 CRIP2 TPM2 C16ORF54 CRYBG2 CAMP CHTF18 DSCC1 FOXM1 SREBF1 BCL9L FGFBP1 TONSL SYT8 SPDEF HR ARHGEF16 TCF7 STIM2 JAG1 MLLT11 PSRC1 MED25 SETD1B LRCH4 ERF SMC2 ARHGAP11A RSAD2 OAS3 HIST1H2AJ CENPA CCNA1 MIS18BP1 IRF7 FIGNL1 MXD3 FBXO5 PASK ESCO2 ZBP1 KIF22 CHEK1 GINS2 PYCARD CKAP2L IQGAP3 PARPBP FAM83D FANCD2 NCAPD2 BRIP1 SPC24 KNTC1 OIP5 TACC3 ERCC6L NUSAP1 CKAP2 MCM5 PBK IFIT1 RACGAP1 AUNIP SPC25 KIF20B HIST1H2AE H2AFX ARHGEF39 DEPDC1 CCNF NCAPG2 NDC80 INCENP CENPE RAD51AP1 GEN1 MYBPC3 IFIT3 OAS2 GINS1 PHF19 CHAF1A CMPK2 CCNE2 XRCC3 TIMELESS IGFBP6 VCAN TCIRG1 LIPG CALML3 DPYSL2 SRSF4 ZFP36 IER3 HMGCS1 HIST1H2BI JUNB MAT2A ACAT2 IFI44L TUBB SLC12A2 FASN PHLDB2 FSCN1 NDUFA7 RRAD HEATR9 MRC2 NACAD MUC1 SORBS3 ZNF367 UBE2S RRM1 MND1 GYS1 PTTG1 SMIM6 TMPO GMNN CDC25B HIST1H2BE HIST1H3G RANGAP1 SRSF2 HIST1H4C HIST2H2AA3 HIST1H1A ZCCHC24 HYAL1 INSIG1 LINC01348 GAS2L1 MSMO1 HMGCR SQLE DIAPH3 ATAD2 MCM6 MVD HIST1H3B FEN1 STRA6 PNPLA3 ITGA11 C5ORF46 CEP131 WDR90 NRARP ELOVL6 PTMS PCSK9 AFAP1L2 FBLN7 HIST1H3H HIST1H4D HIST1H2BL HIST1H2BG MCM4 TTF2 PNKP WDHD1 PLEKHA6 LMNB2 STARD4 CHAC2 CAPN8 HNRNPA2B1 MX2 ATAD5 PPP1R10 HIST1H2BO CCDC142 NMU CD52 RBBP8NL CCDC178 SPTSSB HIST1H2BF HEYL HIST2H4B PHLDA2 HIST2H2BF FADS2 PLA2G4F SLC17A9 HIST1H3J SPRY4 LINC00707 FANCA LGSN SLC13A5 CLDN19 ALPK3 ASPG MTSS1 TRIM17 IDI1 HIST1H1B DHX35 THEM5 ERN2 XRCC2 SUV39H2 NDOR1 MEGF6 PRODH LSS MYEOV MVK HDAC7 NCAPH2 FHOD1 FDPS FDFT1 ELN GAS7 HIST1H3A WNK2 SMC4 FBXO43 PGP NOTCH3 SCHIP1 HIST1H2BJ GAB3 ABCB8 GJB1 SGO1 MCM3 CCDC88A RECQL4 GINS4 NOL6 ELMSAN1 MFSD3 DHCR7 NRM GMPPB PIF1 MICAL2 MFSD2A TRIM47 ESPN RBM20 SLC35D1 CMYA5 CD109 CCDC14 NGEF RAVER1 FAM222A KCNK5 ZMIZ1 KRT7-AS DNHD1 ZMIZ2 LMF2 CAVIN3 SETD1A PADI1 RAI1 AHDC1 CAPN15 CCDC9B PIMREG HIST1H2AB HIST1H2BB HIST1H3F HIST1H3C HIST1H2BM HIST1H3I 1-SEP PRRC2A HIST1H2BN HIST1H3E HIST1H2AH HIST1H2AI PDLIM7 PCDH19 FMNL3 UBALD1 TMEM63A TUBG2 FTO KLC1 CROCC MED15 NUDT22 AQP7 FAM227A OR10AD1 HIST2H3D PLEKHG5 WDR27 PRR33 TBX6 HIST2H2AA4 SARS_COV2_ORF3A SYT5 SARS_COV2_ORF1AB SARS_COV2_ORF8 WDR76 PYCR3 LGALS7 HIST2H3C HIST2H3A SARS_COV2_S PLA2G3 LINC00589 AC234772.3 HIST2H4A ADGRG3 SARS_COV2_ORF10 TEDC2 AL645608.8 AL050343.1 SARS_COV2_ORF7A TEX52 STK31 U47924.1 SMC2-AS1 Z97653.1 AC024267.5 AC010998.2 HIST1H4L HASPIN RNU6-1181P SARS_COV2_ORF6 AL365277.1 SARS_COV2_E DCAF15 CALML3-AS1 ITPKA AC007325.2 AL512353.1 GAS6-AS1 LINC01091 SARS_COV2_N AC012313.8 ANKRD18B AP001363.1 AL031666.1 AP003064.2 C17ORF51 HIST2H3PS2 AL139423.1 HDC AL512791.1 TMEM234 GK-AS1 AL139241.1 AC091057.6 AL354813.1 AC083843.3 LINC02166 AC011337.1 C5ORF63 SARS_COV2_M TNFRSF14-AS1 LINC01132 AC008687.4 AL139246.4 AC114947.2 LINC00920 AL136528.2 Top 500 downregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Wild Type, 24 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/2QOOqYgsO GDF15 HSPA5 SQSTM1 STX3 TRIB3 PCK2 VHL LSAMP NPC2 COPB1 EPB41 SLU7 GOLGA7 ANXA3 LYN SLC5A1 CRYL1 HLA-B ADAM9 SARS RNF41 HMOX1 CEP68 RBCK1 ING4 TARS EPB41L5 CLIP4 ABCG2 CNDP2 HERPUD1 FYN MGAM CAT ANO6 STC2 SPART NEU1 ZC3H12C TIMM44 ADHFE1 ASF1A BRI3 VLDLR BPNT1 CPT1A FECH ZFAND1 N4BP2L2 BTF3 RASEF LINC01133 TGFB2 PIGR ASS1 A2ML1 TTC9 SLC40A1 FGFR2 GULP1 MTRNR2L8 SH3BGRL2 S100P APLF AL035661.1 SNORD17 MTRNR2L12 ADH1C FNIP2 AC013264.1 TCP11L2 RPL30 SNORA79B BCAS1 SNORA73B CDC14B KRT15 SAMD12 ACOT13 RIMS1 ABLIM1 KIAA1143 ABCA1 RPS27 FTL CD24 RNASEL SLC3A2 DHRS7 RETREG2 SLC1A5 PYCR1 ALDH1L2 CREG1 RNASE1 GPNMB PAQR4 BCAT1 PRDX1 SH2D4A GRB10 LGALS3 CLDN7 EPS8 GLDN SNORD3C ALDH9A1 PSMB2 MTHFD2 CA11 RNU4-1 IGFBP3 MARS KLF15 TRAK2 SERPINF1 ABCG1 MYCL IMPA2 PLPP2 CHMP4C FAM84B TRIM16 KITLG BMP3 ATF3 FRAT2 GABARAPL1 NUCB2 CNGB1 OCA2 OSBPL1A ZCWPW1 DACT2 TBL1X BSPRY GATM ULBP1 TMEM45B PSAT1 APOL6 C1R SUCNR1 NAMPT SLC7A11 WARS EPHX1 PSME1 CLIC4 PCBP2 MAP1LC3B FMO1 NFKBIA EIF2S3 ATP6V0E1 UBL3 MED18 COX7A2L EIF3E EFEMP1 NACA CTSH ALDH1A1 PRDX5 NUPR1 DDR2 BNIP3 TMEM50B CD74 TSC22D3 TOMM20 PRPF19 SAP30L JTB EMC3 ATF4 TALDO1 JDP2 LBH MYLIP GTF2B IGFBP5 ACADSB KCNF1 DDIT3 MBP LINC00847 TMEM150C MS4A8 CHAC1 ZNF263 TSPAN31 ANP32A ZNHIT3 HMGB3 NQO1 YPEL5 LAMTOR5 TMEM230 WDR83OS FAM107B SSR2 EPRS PFN2 NAA20 BEX2 NARS SF3B5 FOLR1 MXI1 DNAJB4 MKRN1 PPM1H EFNA1 TNFSF15 PIR CREBRF KLHL24 ANKRD13A DENND5A NECAP1 SLC6A9 ASNS DNASE2 PCGF5 SLC1A4 TFRC ALDH3A1 AARS IARS PELI2 LY96 ANKRA2 GYPC VPS41 SUMF1 LPGAT1 AMFR GARS CRIM1 XPOT FNIP1 TM6SF1 MIA2 ETS2 GPT2 PMAIP1 SLC28A3 HLA-DRA RRAGD ANP32B KLHDC2 C1S PXK PIK3AP1 RPL23A MSRB1 CNPY3 ALDH2 BLVRB EIF1 SERP1 SIX3-AS1 BMF VLDLR-AS1 CBS PRKAG2 SESN2 GRPEL2 TRIM16L BACH1 NCOA7 SLC31A1 RIT1 TNIP1 GK LARS CARS KIT CLCN3 YARS CTSF STX7 ERP29 SEPHS1 HTATIP2 PHGDH CALCOCO2 SULF1 FAM32A MTRNR2L6 WTIP AIG1 ALDH3A2 CHMP1B CCPG1 BUD31 ACKR3 ACAA2 ABHD4 TTLL1 ZNF268 MED6 ANKMY2 ZNF680 PGPEP1 PANX2 HBP1 DKK3 DTX4 ZNF160 ITPR1 RPS6KA2 MCCC1 SELENOK ATP6V0A4 GCLC FUT3 TRPM7 LRRN1 AZGP1 TSPAN15 TXNRD1 BACE2 CBX7 CNTNAP2 ZBTB21 ZFAS1 GSR DAPK1 EIF4EBP1 TMEM192 POLR2F ZFAND5 FBXO32 NDUFA4L2 SLC19A2 TMEM106B BCL2L13 ZNF133 MTHFD1L GPC3 TBC1D15 GCLM SERPINF2 ADH1B AKR1C1 HAX1 RCN1 AIFM2 TSEN15 SHMT2 HRK TOP1MT SEC63 CAVIN2 NOP53 PRDX6 SLC48A1 GPX8 SPSB1 SLC25A20 LHFPL6 ADGRF1 SEL1L3 EIF3L TOMM7 C6ORF48 SLC25A38 LPIN2 SPIRE1 TUBE1 KIF21B UHRF1BP1 TTC39B ADM2 AIF1L LANCL1 CPE DOCK11 RSL24D1 PYROXD1 TRPC1 CEBPG BTF3L4 DGCR6 FBXO34 KIAA0232 ABHD14B ZMAT5 DHRS3 DCAF11 ZNF84 OSER1 PSPC1 SLC20A2 AL355075.4 SNORA74A TMEM9 SNORA49 RNU4-2 SNORA73A SNORD3A MACROD2 TBC1D16 SNTB1 RETREG1 SNORD3B-2 CD99L2 VWA5A LAMTOR4 SLC7A2 EIF3M ZNF845 ADCY9 RAB3B PHPT1 AGA KIAA0513 DDX49 ZNF766 RHBDD1 LYPD6B HRASLS5 YPEL2 SLC35A3 RORA FBXW4 MBTD1 SNORD94 ZNF394 POLR1E RDH10 ULK4 COA5 MPPED2 SH3GL3 DCUN1D4 MR1 EIF2S2 ZNF559 KCNK15 GUCY1A2 TCEA3 GALNT13 SCARNA10 ARHGAP20 BEND6 ZNF480 MKX MRPS18B CEMIP2 MAP1LC3B2 CRBN ZNF844 ZNF229 CBSL UTP14C AKTIP DLK2 PHEX TMEM18 TMEM267 RHBDL1 CYB5D2 GPRASP2 BOD1 BOD1 LINC00365 AC026785.2 ZNF135 ERVE-1 SLC6A16 AL357153.1 ILF3-DT PEX11A LINC01564 SINHCAF AL590617.2 ZNF22 AC010980.2 CLDN20 AC093911.1 SNORD3B-1 FP671120.3 EIF2S3B OSER1-DT AP001207.3 FP236383.2 AP002360.1 FP671120.1 FP236383.1 C4ORF46 TUBA4B AC007325.4 VIPR2 EIF3J-DT FP236383.3 TMEM101 C11ORF1 RF00004 Top 500 upregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Wild Type, 72 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/NEyIIEnCO MPHOSPH10 RSRC2 RBL1 HSPA5 IDE EPB41L2 PTBP2 DDX5 DDX58 YWHAZ DAAM1 CXCL10 TMEM65 ETV1 EPS15 NEDD9 NCL KLF6 SRP54 XIAP EHBP1 F5 RAB8A BRD2 GIGYF2 STAT1 TRIM25 CANX UBAP2L EIF2AK2 OASL FRMD4B ING3 ISG15 TMED5 HERPUD2 MAP3K1 NUB1 LNPEP USP7 PAICS MX1 CHD1 SPTLC1 RBM39 KMO SLITRK6 KLF5 LSM12 MCTP2 GULP1 NFAT5 LMO7 KIAA1217 RASSF6 PAWR RICTOR FAM83B QSER1 TET2 POF1B BDP1 TJP1 EYA4 PTPRZ1 NEDD4L CCNA2 SCARB2 LDLR IFI44 FKBP5 ASPM SMAD1 EPSTI1 MERTK IGLV1-51 MKI67 SCD RASGEF1B TOPORS STAM CDV3 SPARCL1 ABI3BP STIM2 MAP3K4 SOX6 SMC2 RSAD2 OAS3 MIS18BP1 SLAMF7 IFIT1 GEN1 IFIT3 IFIT1B OAS2 PHF11 XAF1 USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 NT5C3A PARP9 PARP12 SAMD9L PARP14 F3 SP110 DTX3L NPNT MAT2A LUC7L3 RPL22 IFI44L SLC12A2 EPC2 ZMYND11 MBNL1 BMS1 CCNL1 FNDC3B TCF4 ZFP91 YTHDC1 RGS4 AXDND1 KIAA1551 TCERG1 KBTBD8 CELF2 CIART PLA2G4C MUC5AC TIPARP ZSWIM6 ZNFX1 GTF2E1 TMEM33 HSP90B1 BCOR ATIC UGT8 SYNCRIP LEO1 CWC22 SIRT1 INTS6 PTBP3 SRSF2 ANKRD1 NOP14 SETD2 MBD5 MAP2 HIVEP2 C3ORF52 GABPB1 TRA2B SLFN5 PPM1K LGALS8 PP2D1 TRIM21 ZC3HAV1 TRIM5 MORC3 NID1 PRPF39 ANKRD36B IFI6 FNBP4 FAM13B LAMP3 DDX60 MBNL3 SMC3 EIF3A NEB STARD4 XRN1 SP100 LRIF1 HNRNPA2B1 BCL10 MX2 IFIT5 HERC5 RBMX DDX60L SAMD9 GBP1 PRRC2C EIF5B SMC5 ATRX ASH1L TP53BP2 FNIP1 BOD1L1 PNISR THOC2 SDAD1 FMNL2 RSF1 ESCO1 WEE1 HDX BAZ1A NFE2L3 DUSP4 PRRC1 SMCHD1 RABGAP1L ROCK1 DYRK1A ZNF280D ATF7IP BACH2 NR4A1 FANCA CDC14A DHX36 OLA1 RANBP2 NCF2 EEA1 SPEN PIAS1 AP3M1 PPID TARSL2 ZBTB38 NUP153 BHLHE41 FIP1L1 ATP7A HELZ EML4 ZBTB10 NEMF REV1 NSRP1 RBBP6 U2SURP USP53 PTER PTP4A1 PDIA3 ACSL4 ZNF326 CCAR1 WDR43 DNAJC2 ZNF518B PTPN12 GOLGA4 PPP2R2A BEST3 IQGAP1 STK24 EPC1 NOL8 PPP1R12A SREK1 ANKRD17 DHX9 GSPT1 RAB6A ACBD3 CPNE3 LCORL FOXP1 STEAP2 TRIM24 SENP7 LIN7C JMJD1C UNC5C SMC4 PIK3C2A ARHGEF38 TAS2R14 SENP6 AQR TMEM106B PPM1D VCPIP1 MTHFD1 RFC1 TRIP11 SCAF11 TMEM179B ZRANB1 SLCO4C1 UGT2A1 MAP3K2 SFPQ CCDC88A BCLAF1 NOLC1 GTF2H1 ARID2 MGA ZBTB11 WAC DDX24 LRIG2 KBTBD2 NRCAM HIVEP1 DCAF17 SLK TLK1 ZNF608 GPSM2 TROVE2 CMYA5 CCDC14 TCEA1 ZC3H6 ZNF146 JMY ARHGAP21 STAG1 ZNF131 PHF20L1 TDG SERTAD4 TTC17 PDE10A HNRNPDL CFAP97 PAXBP1 LINC01963 NCBP3 PM20D2 KAT6A PHACTR2 ZBTB1 PDZD8 TMTC3 CLIP1 SLTM WAPL ARHGAP12 GPATCH8 CNST ZFR KMT2E RALGAPA1 BAZ2B CWC25 PIP4K2A ZNF75A GOLIM4 TUT4 SOS1 EMSY TENT4B SOS2 PRRX1 ARID4B TLK2 ARAP2 LINC02532 LNPK DOCK7 TUT7 MMP25-AS1 EIF4G3 ZNF37A ZC3H13 STYX HNRNPR HNRNPU RBM25 PRPF4B CHD9 RBM48 INO80D C5ORF51 DNAJC27 SHLD2 VPS13C THAP5 EFR3A CDC5L OPA1 KIAA0586 DAB2 ARHGAP26 SRRM1 BPTF PROSER1 FTSJ3 PDS5A PHF3 NSUN2 CCSER2 UPF3B CHD7 PPP1R12B PGGT1B ZNF260 MOB1B SSR1 YLPM1 SMARCAD1 CTDSPL2 KATNBL1 MAPK1IP1L TAOK1 LMBR1 FAM135A RNF144B DIS3 CRYBG3 PRPF40A GPD2 AK5 DPP10 TCHH ICK SNX27 RNGTT RUFY3 RBM26 URI1 GINS3 PPP6R3 MTMR10 NPIPB11 RGPD6 FBXW10 EYS CNOT7 RGPD5 TRIM33 OSBPL3 RIF1 SCRG1 CCDC122 CDRT4 PAPOLG PHF14 LARP1B DCAF16 LRRC37B RGPD8 INTS2 BRD7 SARS_COV2_ORF3A SARS_COV2_ORF1AB SARS_COV2_ORF8 SARS_COV2_S LINC00589 SARS_COV2_ORF10 SARS_COV2_ORF7A SARS_COV2_ORF6 SARS_COV2_E SARS_COV2_N AL139241.1 AC011337.1 C5ORF63 SARS_COV2_M MUC19 C9ORF131 RF00012 LINC00970 L3MBTL3 HELLPAR RNVU1-15 LRCH3 LINC01291 AC011374.1 ZNF625 DYNC1I1 RNU5D-1 LINC02240 AL031123.2 AC023300.2 C5ORF22 AC092611.2 ZC3H14 KIAA0391 CCDC66 Z97832.2 NSMAF AC016831.5 MIR3150BHG AC005962.1 PSMA3-AS1 RAB6D SARS_COV2_ORF7B AC068888.1 ZNF860 Top 500 downregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Wild Type, 72 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/NEyIIEnCO NBL1 MVP FBXW5 CHPF COMT DGAT1 IRF3 PPP2R1A TSPO ESRRA PUSL1 YIF1A FURIN VILL KCNQ1 GPAA1 UBTD1 KIAA2013 CTSD TST ISYNA1 POR PLD3 FAU PEPD ELOB AGPAT2 ACADS REEP6 SMO RHBDD3 H2AFJ WDR34 NDUFV1 DDT STXBP2 HIST1H4B CCNO MZT2A PITX1 RPL39 RPS29 PTPA NACC1 TMC6 ARHGEF10L DPP7 CHID1 XAB2 EMC10 FKBP8 SNRPB GRK2 CD81 QSOX1 CYBA CORO1B SLC16A3 MAP3K11 TMED9 SYNGR2 NCLN TWF2 MRPL12 SMARCD3 ADAM15 DDIT4 AP2S1 H1FX PAQR4 GALK1 CLDN7 SNORD3C ALDH4A1 SIGIRR MIR3648-2 CRIP2 MIR3648-1 ADGRB2 ARVCF ZFYVE28 BAD B4GALT7 ABCC6 PKP3 CRB3 ADAP1 LTF CLDN4 THEM6 PPP1R16A PAK4 ARRDC1 CLDN3 GIPC1 PPP1R37 SLC2A4RG SLC52A2 EEF1D EPPK1 SLC4A2 LRP5 WNT3A SLC9A3R2 PTPRU ZNF628 PWWP2B DGCR2 CYHR1 SYTL1 PITPNM1 LFNG SCAF1 OGFR SBNO2 RAB43 PLPPR2 TMEM8A EPN1 PRR12 H2AFX TNFRSF18 HIST4H4 DNPH1 CDT1 SLC32A1 TTYH3 RPL28 RPS28 LRFN4 SMDT1 PSMB10 SIPA1 CHCHD2 RPL3 RPS19 SNX17 RPS5 COX8A VPS28 TMEM160 JUND NDUFB11 CD74 RPS9 NDUFB7 PEX6 LYPLA2 JTB ROMO1 ATP6V0B FAM53B SMIM22 MXD4 PSKH1 NUDT16L1 GUK1 CD151 SCAND1 COX14 CCDC85B PGLS RRAD LYPD2 TNFRSF14 TOR4A NEURL3 IRF2BPL TMEM258 MRPL34 ATP6V0E2 CIB1 RBM42 C19ORF70 TMEM208 NDUFAB1 CKB ASL C12ORF57 ZNHIT1 CCDC124 LSM7 NOSIP POLR2E SSR4 PSMA7 RPL29 BBS5 MAD2L2 CHTF8 SF3B5 ETFB C1ORF122 TSEN34 YDJC RANGAP1 HIST1H4C HIST2H2AA3 VPS51 PRR15 B3GALT4 GALNT18 DHRS13 IL34 TMEM115 MVD ODF3B TCTEX1D2 BCL2L12 MSLN CACNG6 TMEM121 LRRC26 STRA6 GSDMD TAPBPL ZMYND10 SSNA1 TMEM229B C19ORF25 ISOC2 BTBD2 FBLN2 SLC43A2 HIST1H4F C6 CDC42EP5 BOP1 CYSRT1 TPRA1 DEGS2 LENG9 SNHG9 HES4 ZNF581 RHBDF2 SERF2 COPE RNH1 KLHDC8B ANAPC11 UBL4A RGS19 ARRB1 MRPS12 CPPED1 PPP4C NR1H2 CD82 FADD CHMP1A AURKAIP1 C9ORF16 PLEKHJ1 STK25 MPST ARMC6 ABHD8 NUBP2 C19ORF24 NACC2 XYLT2 SPNS1 TBL3 ACTR1B COMTD1 FBXW9 MZT2B ZNF524 PEX10 DGCR6L GPRC5C ASNA1 ITPA RABEP2 TRAPPC6A GNPTG NUDT14 ZNF219 FDXR RNPEPL1 PRADC1 MBD3 RPS19BP1 FASTK ALDH16A1 TMEM129 KATNB1 REPIN1 PPDPF CYC1 ILVBL PQLC1 DAPK3 NCAPH2 NDUFA11 GAS6 TSSC4 SIVA1 PRSS8 PLIN3 SIRT6 YIPF2 PLXNA1 VWA1 FXYD3 EHMT2 RAB40C LRWD1 HSF1 ATP2A3 BIK ARSA CYB561A3 RAB26 STK11 ATP13A2 RAB24 CPTP IL17RC ABCB8 CYP2W1 MRPS26 PIN1 TARBP2 PKN3 RPUSD1 IFRD2 AKR7A2 ENDOG NOP53 TXNRD2 MAP2K2 SELENOH NAPRT TMEM219 MRPL23 SDSL JOSD2 SLC41A3 FBXO2 POLR2L GMEB2 MFSD3 CAPS COMMD4 GPS1 C7ORF50 LAGE3 HS6ST1 MRPL41 CTXN1 PMVK HES6 TMEM141 NTHL1 GAMT THAP11 SYNGR1 ESPN CPAMD8 INTS5 SLC39A3 ZDHHC12 DGCR6 CACTIN NR2F6 TMED1 A4GALT ALKBH7 FAM98C WDR18 OXLD1 ECI1 METTL27 NME3 ZDHHC24 MRPL55 CARD19 PDLIM4 CCDC167 MED16 SNTA1 CCDC61 TMEM161A HPS6 REX1BD YIF1B METTL26 TP53I13 DDTL NCKAP5L CAPN15 AL355075.4 TMEM134 COMMD5 TMEM9 SNORD3A TBC1D16 ZNF428 CBX6 FBXL18 DOHH SNORD3B-2 HDAC11 LAMTOR4 SCRN2 HIST1H4J PEX16 SBF1 HIST1H4K HIST3H2A RMRP PHPT1 FBXL15 ST6GALNAC4 TSPAN9 RNF126 DDX49 CACFD1 MGAT3 PLA2G16 AES CADM4 FAM234A MFSD10 ABHD17A SLC35B2 ADGRL1 RASSF7 E4F1 TSC22D4 SNORD94 KLHL26 FNDC11 VSTM2L TRABD TRAF7 SLC25A6 TSR3 C4ORF48 LZTS2 CCDC22 SPATA2L PUF60 TMEM132A LYNX1 HAGHL CSNK1G2 SSBP4 MIIP PEX11G ZNHIT2 TRMT61A B3GAT3 HIST2H3D EEF2KMT MCRIP1 MCRIP2 KLC3 SHISA8 MIEF2 CHST12 DLK2 FAAP100 CASC10 AC100810.1 GATD1 HIST2H2AA4 BX255925.3 LGALS7 AL356488.2 DCAF15 SNORD3B-1 TUBA4B AC007325.4 TMEM101 NELFB TMEM125 SCARF2 AP001527.2 SYNE4 HIST3H2BB AC005790.1 MIR3687-2 AC009237.14 MIR3687-1 DEF8 TERC SAYSD1 CHCHD5 FAAP20 PAXX PIP5KL1 TMEM250 AL121790.2 ZNF837 HS3ST6 AC092171.3 TEDC1 Top 500 upregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Mutant, 8 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/jeVWIUOdS ADAMTS1 UHRF1 RBL1 EGR1 MALL YWHAQ KPNA2 YWHAZ DDX21 HEATR3 TPM4 TPM3 TMEM97 PKM ANXA2 ST14 FURIN ETV4 NCL SIGMAR1 SLC27A4 TUBA1C TUBA4A HIST1H4A SFN PTPRH PLAT PHB MSN ETV5 TGFB1 THOP1 DIAPH1 PTGES2 REN SCARB1 PAICS PLP2 ATAD3A METTL8 LRRC8A ENO1 NMB MT2A KRT18 SLC16A9 KRT7 HIST1H2AL CEBPD KRT4 KRT17 ECM1 AQP5 HIST1H4I UPK1B HIST1H2AG GALNT5 SPRR1A HIST1H2BK TRIM7 S100A2 ZNF467 KRT8 EMP2 CCND1 SPRR1B ITPK1 UNC93B1 NACC1 AQP3 TOMM40 VASP GSN FLNA GART SNRPB LMNA INF2 EMP3 ARHGDIA ACLY NCLN TIMP1 DHCR24 MYBL2 TICRR CCNA2 CLSPN TK1 ATP5MC3 CAPG MRPL12 LMNB1 TUBG1 NLN SLC16A1 AURKB ADAM15 SHCBP1 LDLR FKBP5 MCM2 FH FADS1 CDC6 E2F1 ORC1 SAPCD2 MCM10 GSTO1 NME1 TPX2 DUSP7 CEP55 KIF23 PKMYT1 MKI67 LDHA CDC45 KIF20A DTL SCD NCAPG BEGAIN CRIP2 TPM2 LGR6 CRYBG2 AKAP12 CAMP B4GALT2 KLF13 DSCC1 ABCE1 PKP3 ACTB HMGA1 LAD1 GJB3 SREBF1 FGFBP1 PSMD6 ANXA8 SCNN1A LSR ANXA8L1 SLC52A2 SPDEF HR EREG KRT13 EPN1 ERF HIST1H2AJ CCNA1 CREG2 CHEK1 GINS2 DUSP2 PYCARD FAM83D MCM5 AUNIP HIST1H2AE H2AFX COTL1 SYT12 LRP8 GINS1 CHAF1A CCNE2 MDFI ALDH1B1 IGFBP6 LIPG CAV2 PFN1 ZFP36 IER2 LRFN4 IER3 HNRNPM TUBA1B FOS ACTG1 DUSP1 HMGCS1 HIST1H2BI JUNB JUN ACAT2 COX8A EIF5A DRAP1 SERPINB9 PSMD3 TUBB SH3BGRL3 TMEM160 ITPRIPL2 EFNB1 ROMO1 S100A16 CFL1 TUBB2A RBM3 ANXA1 FASN EFHD2 PHLDB2 SRSF3 FSCN1 S100A10 CD151 S100A13 CCDC85B RRAD TGFB1I1 NSG1 OTOP3 MRC2 SERPINB4 RTN4R SORBS3 DUSP5 ZNF367 FOSB UBE2S GYS1 TXNDC17 RBM42 HSP90B1 SRM PGAM1 CKB GALNT7 PA2G4 PSME3 SEH1L NPM3 UCHL3 DKC1 AMD1 NAA50 PSMA7 GMNN TUBB6 TMSB10 C1ORF122 ODC1 HIST1H2BE HIST1H3G GOT2 RANGAP1 SRSF2 HIST1H4C NOP14 HIST2H2AA3 HIST1H1A HYAL1 INSIG1 GAS2L1 MSMO1 HMGCR SQLE CSE1L CEMIP MCM6 MVD HIST1H3B SLIRP GMDS ANXA10 PNPLA3 NRARP ELOVL6 PTMS RARRES2 PCSK9 HIST1H3H HIST1H2BL APCDD1 MCM4 PHACTR3 ALYREF PLEKHA6 GALNT12 LMNB2 STARD4 CHAC2 HNRNPA2B1 RPL22L1 GBP1 CKAP4 GJB2 EIF5B BOP1 ACOT7 EMP1 HIST1H2BO GMPR PRSS3 NMU ACTN1 COPE HNRNPA1 MBD2 CD44 SPTSSB HIST1H2BF GAS1 HEYL PDLIM2 KRT6B ZBED2 BCAR3 PHLDA2 SERPINB8 NEK6 FADS2 NR4A1 PLA2G4F KRT6C KRT6A ANO1 HIST1H3J LINC00707 SLC13A5 ITGA6 IRAK1 TYRO3 GLRX3 FTSJ1 IDI1 PRMT1 MAP4K4 CA12 FAIM2 HIST1H1B MRPS12 GNPNAT1 FARSB TPM1 ATP5MC1 C9ORF16 APRT THEM5 ARMC6 PLEK2 DNAJB11 PDIA3 RIOK1 TBL3 COMTD1 CLTB LRP3 LSS TTLL12 ZNF219 MVK SH2D5 PCDHGC3 MFSD12 MPC1 ACSL1 ANKRD22 KLK10 E2F4 PLXND1 PPP1R14B LETM1 CTPS1 C19ORF48 FDPS RPS6KA4 FDFT1 PC SPCS3 ELN CD320 SREBF2 CPA4 GAS7 GTF3A HIST1H3A SLC22A3 SERPINB13 SRPK1 RDH11 GALNT6 PGP GPC1 RAET1E LRRC59 HIST1H2BJ ATP13A2 PGAM5 PSMG1 PTBP1 CYP51A1 MRPS26 ACSS2 NAA15 LIMK1 MCM3 PPP2R5D PRMT3 MRTO4 MCMBP MYBBP1A HNRNPAB NUP188 RRS1 IFRD2 GRWD1 NOLC1 ENDOG CS EHD2 HSD17B12 NOL6 DHCR7 C7ORF50 NSDHL MMAB SLC25A1 EBP GMPPB LGALSL MFSD2A TRIM47 PARD6G CD109 NGEF TMEM104 DDIAS GPATCH4 RAB27B CAVIN1 NDUFS8 BOK GALE JPT1 9-SEP PFKP CAVIN3 FARSA GOLIM4 PADI1 PALLD LPAR5 CAPN15 ERG28 NOP16 PDCD5 HNRNPR HIST1H2BB SLC25A13 HIST1H3F HIST1H3C HIST1H2BM HIST1H3I HIST1H2AH HIST1H2AI PDLIM7 FBXL15 CAMK2B ATP5F1D MMP28 NGFR RNF126 SLC6A8 ZDHHC14 TRAC RIN1 ADCY3 PGAM4 RUSC1 HIST2H3D KCNQ5 POTEE P3H2 SLC35F2 ADAMTSL5 LZTS1 HIST2H2AA4 WDR76 BX255925.3 AL450992.2 AC126365.1 PYCR3 IL12RB2 LGALS7 HIST2H3C HES5 HIST2H3A PLA2G3 C17ORF82 CCDC3 C16ORF74 Top 500 downregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Mutant, 8 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/jeVWIUOdS GDF15 UGT1A7 CXCL5 PCK2 LSAMP COL4A5 EPB41 SLC7A7 SCN2B ATXN3 LYN SLC46A3 CEP68 ATM ING4 NCKAP5 TARS NR3C2 ABCG2 HERPUD1 MGAM EPHX2 STC2 ZC3H12C PCMTD2 ADHFE1 INTU VPS13B LIFR ALDH6A1 ZKSCAN1 CPT1A GPR155 RPS6KA5 N4BP2L2 BCL2 NBEA MECOM TSHZ2 TGFB2 PIGR ZNF532 FRK CFTR RARB CGNL1 SLC40A1 ADCY2 FGFR2 LRIG3 LURAP1L PNRC1 COLCA1 KIAA1324 ADH1C TCP11L2 PLCB4 SPRR2D SNORA73B ZNF827 KRT15 PRSS16 UTRN MAPK10 SIX4 ANK3 ABCA1 KCNQ1OT1 ZBTB20 FTL TTC14 PTGER4 MBD6 RNASEL ACSS1 TGFBI SLC1A5 PYCR1 ALDH1L2 NAIP CHRNA7 ITGA7 BCAT1 DPYD MMP19 MTHFD2 COLGALT2 PBXIP1 ZNF266 MARS COL5A2 SLC2A5 PIK3IP1 FAM20A FAM84B BCAS3 SPARCL1 NKD1 KITLG BMP3 INPP5D WNT5A SPRY3 ATF3 GABARAPL1 NUCB2 ZCWPW1 DACT2 TRPV6 ZNF862 RGL2 GATM CD27 ULBP1 TXLNB PSAT1 CHL1 XAF1 CH25H APOL6 C1R STAT2 SAMD9L RNF213 UBA7 ATP13A4 SVOPL CLIC4 PCBP2 MAP1LC3B FMO1 PTPRM SEMA3C NR1D2 NUPR1 DDR2 BNIP3 RBMS3 DDX17 PEX6 ATF4 JDP2 LBH MYLIP TMEM260 EIF4A2 IVNS1ABP CCNL2 GLRX5 KCNF1 DDIT3 TRIM22 ERMAP HMCN1 TMEM150C INSR ZFP14 L3MBTL1 SEC31B BAMBI ZSWIM6 CHAC1 TAF1D FAM107B EPRS BEX2 MXI1 DNAJA4 RSRP1 MKRN1 ZNF512 OGT TAPT1-AS1 TNFSF15 FOXO4 CREBRF TTC21B KLHL24 DENND5A REL SLC6A9 CIITA ATP10B ASNS TNNT3 DNASE2 PPM1K DLL1 POU2AF1 SLC1A4 TFRC AARS PELI2 GPRASP1 TESK2 VPS41 HHAT NBPF11 TIA1 SP100 TRANK1 GARS PPP1R9A XPOT FNIP1 ANKRD12 CEP290 HERC1 SLC25A36 GPT2 BTN3A3 PMAIP1 SLC28A3 BTN3A1 C1S BTN3A2 PIK3AP1 ALDH2 EIF1 PUM2 NAV1 IGIP KCNE3 VLDLR-AS1 CBS LMCD1 CLK1 PAMR1 SPRR2E NCOA7 VNN3 C4B RIT1 GK LARS CARS KIT YARS CTSF FAM111A STX7 ERP29 PDCD1LG2 HTATIP2 GGT2 PHGDH SULF1 SLC35F5 SMYD3 AIG1 CALCOCO1 CCPG1 ACKR3 TTLL1 C14ORF132 KCTD7 PGPEP1 CYB5RL SYNE1 MATN2 PANX2 DSCAML1 ZFYVE26 ALPK1 HBP1 DKK3 ITPR1 SREK1 FAM219B LRIG1 RPS6KA2 MCCC1 PPARA ACSM3 ATP6V0A4 GREB1 CDK19 RALGAPA2 CHD6 IMMP2L SLC2A12 CSMD1 CCNG2 CBX7 TRIQK ZBTB21 NPIPB4 ZFAS1 BCL2L11 SLC9A9 TP53BP1 TLR5 GOLGA8Q SPDYE6 ZFAND5 FBXO32 PRR5L VPS16 RAB26 NDUFA4L2 ZNF75D USP49 ENOSF1 DNAH5 ABCA5 MPP2 ABTB1 WDR48 EXOC4 UGT1A5 ADH1B UGT2A1 TGIF1 SLC10A5 RFX3 RCN1 WSB1 LNX1 IL11RA SHMT2 TOP1MT VPS8 CAVIN2 GPX8 DTNA PLCG2 FMO4 ACSF2 NAALADL2 KIAA1147 SEL1L3 DIP2C TUBE1 TTC39B ADM2 AIF1L NBPF14 MANBA SEMA6D TBC1D5 PUS10 NMRK1 CPE KCNH1 RSL24D1 CEBPG IFRD1 JMY CPAMD8 C1QTNF6 MKL2 ZBTB40 FBXO34 KIAA0232 OPHN1 DNAJC4 DHRS3 ANKRD10 ZNF84 PLPP3 ZNF248 HECW2 SNORA49 AF117829.1 MIR3609 NBPF26 SNORA73A MACROD2 TBC1D16 LRRC37A C22ORF46 TTC28 SYNPO2 SNORA12 PAXIP1-AS2 SLC7A2 SNORA28 ZNF555 TRIM45 PHKB PHYKPL PCMTD1 TRIM66 PPIP5K2 WDR19 ADGRL3 ACACB SLIT3 GARNL3 RN7SK TBCK ZNF766 NKTR FAXDC2 YPEL2 SLC35A3 FOXN3 KIAA1109 PHF1 RORA MBTD1 POFUT2 DGLUCY COA5 GNG7 MR1 GPRC5B EIF2S2 SPIN3 GUCY1A2 TCEA3 RCBTB1 GALNT13 FHOD3 ZNF483 PCED1A ARHGAP20 BEND6 GOLGA8O CAPN9 CECR2 SPDYE2B TMEM116 NPIPA7 SPDYE2 HEMK1 CNTNAP3B CBSL ZNF300 NPIPA8 LRRC37A2 NSUN7 CACHD1 NWD1 SPEF2 RHBDL1 GPRASP2 PYROXD2 ELMOD3 MARF1 CUZD1 F8 AC124312.3 C20ORF204 ZNF577 RAD51B GTF2IRD2 KHDC4 LINC00365 AP002026.1 AC245100.6 AP000866.1 GTF2IRD2B AL356488.2 SMIM10L2A SCARNA9 TTLL9 CFAP69 CERS4 ZNF135 ADGRV1 GMDS-DT AL158071.5 ERVE-1 PARD3B SLC6A16 RIC3 ILF3-DT AP001207.3 PIP5KL1 MAATS1 AC010998.3 SPRR2F MEGF11 AL928970.1 AL121672.2 KIAA2012 AC007681.1 AC019117.1 LINC00865 AL356740.1 AC092683.1 AC107884.1 LINC00886 GAS1RR KCNE1B IQCA1 AC131971.1 DNAJC3-DT AC240565.2 C15ORF59 AADACL2 AC073335.2 GOLGA6L9 AC115989.2 AC020915.3 AL627309.2 U73166.1 KCNJ1 C4ORF17 Top 500 upregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Mutant, 24 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/ma2RFrgMh GPR151 UHRF1 RBL1 GLYCTK EGR1 TRIM59 IRF3 KPNA2 TBC1D29 TP53AIP1 TMEM97 ETV1 CENPF ETV4 CIT DNMT1 TUBA4A HIST1H4A BRCA1 FBXW12 PLAT ETV5 CD4 FAM72B EVL CSF2 PAICS IGSF9 TMEM253 FBXL6 CNTD1 SERPINB11 HIST1H2BH HIST1H4B HIST1H2AL KRT4 ECM1 LRRC18 HIST1H4I HIST1H2AG LINC00342 CFH ANKRD36C HIST1H4H TRIM7 HIST1H1D STMN1 GSN NLRP1 PLK1 TIMP1 EXO1 GAS2L3 MYBL2 TOP2A TICRR ZWINT CDCA8 CCNA2 CLSPN TK1 TROAP LMNB1 CCNB2 GTSE1 CDKN3 UBE2C KNL1 AURKB SHCBP1 LDLR KIF18B NUF2 DEPDC1B HMMR SPAG5 FAM72A BUB1B MCM2 KIF2C CDC25A KIF14 KNSTRN ASPM AURKA DLGAP5 ESPL1 FADS1 RRM2 CDC6 E2F1 BIRC5 ORC1 KIFC1 KIF4A MCM10 KIF15 SMTN FAM72C PRR11 CDCA2 KIF11 BRCA2 TPX2 CCNB1 ANLN NCAPH CEP55 CDCA3 CDC20 KIF23 PKMYT1 SKA1 HJURP TTK MKI67 LIPA CDC45 KIF20A SCD NCAPG BEGAIN TPM2 LGR6 C16ORF54 CRYBG2 CAMP PLCXD1 STAR DSCC1 FOXM1 SREBF1 FGFBP1 MYO19 HR TCF7 STIM2 JAG1 MLLT11 PSRC1 CENPN GPR162 SMC2 ARHGAP11A E2F8 OAS3 HIST1H2AJ IDO1 CENPA CCNA1 FIGNL1 C1ORF112 FBXO5 ESCO2 FANCI APOD KIF22 CHEK1 GINS2 C17ORF53 CKAP2L IQGAP3 PARPBP FAM83D FANCD2 NCAPD2 BRIP1 SPC24 HELLS KNTC1 TACC3 ERCC6L NUSAP1 CKAP2 MCM5 PBK BORA ARHGDIB RACGAP1 AUNIP SPC25 KIF20B HIST1H2AE MELK ARHGEF39 DEPDC1 CCNF NCAPG2 CENPH NDC80 LAG3 INCENP CENPE RAD51AP1 GEN1 CIDEA LRP8 GINS1 PHF19 CHAF1A CCNE2 HAS3 LGI3 IGFBP6 VCAN CALML3 RIMKLB DPYSL2 FOS HMGCS1 HIST1H2BI MAT2A LUC7L3 ACAT2 TAGLN TUBB SH3BGRL3 SLC12A2 ITPRIPL2 PLEKHG2 FASN PHLDB2 NRP1 FSCN1 S100A13 STARD9 TGFB1I1 SPOCK3 SYNGAP1 HEATR9 TCERG1 GPR182 MRC2 NACAD SAMD15 ZNF367 UBE2S RRM1 MND1 PTTG1 VMP1 C2ORF74 DONSON RFC4 TMPO CDC25B HIST1H2BE HIST1H3G SRSF2 DQX1 HIST1H4C HIST1H1A HYAL1 INSIG1 LINC01348 MSMO1 HMGCR SQLE DIAPH3 CSE1L ATAD2 CEMIP CDCA7 FANCG MCM6 MVD HIST1H3B TRA2B GSTCD FEN1 PNPLA3 ITGA11 NRARP ELOVL6 PCSK9 RUSC1-AS1 PIGL AFAP1L2 SYT16 HIST1H3H HIST1H4D HIST1H2BL HIST1H4F HIST1H2BG TTF2 MCM7 WDHD1 DNA2 LMNB2 STARD4 CAPN8 HNRNPA2B1 MX2 SH3PXD2A-AS1 FLG2 ATAD5 HIST1H2BO ORC6 NMU CCDC178 HIST1H2BF HCN3 NEK6 FADS2 PLA2G4F SLC17A9 HIST1H3J SPRY4 LINC00707 FANCA LGSN CLDN19 ALPK3 GSN-AS1 IDI1 CA12 HIST1H1B DHX35 ADAM22 EPPIN THEM5 XRCC2 SUV39H2 LSS MVK FDPS TRIM13 FDFT1 ELN CRYGS ZBED5 GAS7 HIST1H3A MIR222HG SMC4 TTC30A PCLAF RAET1E HIST1H2BJ TLR10 ABCB4 GJB1 SLC29A2 SGO1 MCM3 CCDC88A NUP205 GINS4 ALDH7A1 NOL6 DHCR7 MMAB NRM GMPPB PIF1 MICAL2 MFSD2A RBM20 PADI3 CMYA5 CD109 NGEF CAPRIN2 RFC3 DDIAS KRT7-AS DNHD1 PADI1 AC138150.1 ALG1L PIMREG HIST1H2AB HIST1H2BB HIST1H3F HIST1H3C HIST1H2BM HIST1H3I 1-SEP TMEM131L HIST1H3E HIST1H2AH HIST1H2AI PDLIM7 REXO5 FMNL3 SOX8 TMEM63A TUBG2 DSN1 FTO NPIPB9 HEATR5B FANCB TTLL6 AQP7 GALT FAM227A HIST2H3D BTBD18 FBXW10 OSBPL3 WDR27 EFR3B INTS2 LZTS1 SARS_COV2_ORF3A SYT5 SARS_COV2_ORF1AB WDR76 AC126365.1 LGALS7 HIST2H3C HIST2H3A SARS_COV2_S PLA2G3 LINC00589 AC234772.3 ADGRG3 SARS_COV2_ORF10 SARS_COV2_ORF7A TEX52 STK31 U47924.1 SMC2-AS1 HIST1H4L HASPIN SARS_COV2_ORF6 SARS_COV2_E CALML3-AS1 AL512353.1 LINC01091 SARS_COV2_N AC012313.8 AP001363.1 AL031666.1 AP003064.2 HDC TMEM234 AL139241.1 AC091057.6 AL354813.1 AC083843.3 AC011337.1 C5ORF63 SARS_COV2_M LINC01132 AC008687.4 AC114947.2 AL136528.2 MUC19 RF00012 AC068888.1 AC092683.1 AL136115.1 AP002008.1 AP003392.1 VWA3A LINC02568 LINC01588 AC078846.1 CHL1-AS1 AC087257.1 AC022400.1 AL162727.1 AL356608.1 RNVU1-6 AC024267.3 SNORC RAB30-AS1 AC010401.1 AC012368.1 PKP4-AS1 LINC01206 GRTP1-AS1 AC024257.3 AC025178.1 NPIPB15 SSBP3-AS1 AL109761.1 AP000646.1 GIPR PLAC4 AL590226.2 KPNA7 AC004067.1 GLB1L AL049840.1 AC099850.3 AL450998.3 AL157838.1 AL023803.2 AL357093.1 AC025031.4 AC092535.4 AC098829.1 C22ORF15 AC108681.1 MROH9 CSDC2 AC122129.1 Top 500 downregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Mutant, 24 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/ma2RFrgMh FCGRT GDF15 HSPA5 TMEM37 STAT3 SQSTM1 STX3 TRIB3 PCK2 LSAMP COPB1 ANXA3 LYN NDRG1 CRYL1 HLA-B ADAM9 KCNQ1 SARS RNF41 ANXA11 HMOX1 CEP68 UBTD1 RBCK1 ING4 HLA-C TARS EPB41L5 CLIP4 ABCG2 CNDP2 HERPUD1 FYN PABPC1 MGAM PEPD EXOSC5 CAT ANO6 STC2 SPART NEU1 SEPHS2 ZC3H12C TIMM44 ADHFE1 ASF1A BRI3 VLDLR CPT1A ZFAND1 BTF3 RASEF BPIFB1 RPS16 MUC21 LINC01133 TGFB2 PIGR ASS1 TTC9 FGFR2 GULP1 MTRNR2L8 SH3BGRL2 SNORD17 PNRC1 MTRNR2L12 MTRNR2L1 ADH1C FNIP2 CDC14B CYBRD1 KRT15 ACOT13 RIMS1 TACSTD2 ABLIM1 LCN2 ABCA1 RPLP1 SYBU FTL CD24 RNASEL SLC3A2 DPP7 PGD DHRS7 SH3BP2 BST2 HLA-E SLC1A5 PYCR1 ALDH1L2 AC093627.4 RNASE1 PAQR4 CES1 BCAT1 PRDX1 SH2D4A GRB10 LGALS3 CLDN7 CBR1 EPS8 SNORD3C MTHFD2 CA11 MIR3648-2 MIR3648-1 COLGALT2 IGFBP3 HINT3 MARS KLF15 TRAK2 SERPINF1 ABCG1 MYCL IMPA2 PLPP2 CLDN4 CHMP4C THEM6 PROSER2 FAM84B SULT2B1 TRIM16 GIPC1 SLC7A5 TPD52L1 SLC7A1 FZD1 KITLG BMP3 ATF3 FRAT2 GABARAPL1 NUCB2 OCA2 PTPRU ZCWPW1 DACT2 CEBPB TBL1X BSPRY GATM ULBP1 SECTM1 TMEM45B CFD PSAT1 APOL6 C1R NAMPT ADM MUC5B SLC7A11 WARS EPHX1 TRIL FTH1 CLIC4 PCBP2 RPS28 MAP1LC3B CHMP4B EIF3G FMO1 RNF187 EEF2 GSTP1 KLHL5 UBL3 PXDC1 COX7A2L EFEMP1 CTSH ALDH1A1 PRDX5 NUPR1 DDR2 BNIP3 CD74 TSC22D3 NDFIP1 PRPF19 RGCC SAP30L JTB ATF4 TALDO1 SLC39A1 JDP2 LBH MYLIP TMEM260 HCK CYP2S1 IGFBP5 GPX4 KCNF1 DDIT3 MBP TAGLN3 LINC00847 TMEM150C BAMBI CHAC1 HMGB3 NQO1 YPEL5 FAM107B EPRS PFN2 NAA20 BEX2 NARS SF3B5 FOLR1 MXI1 DNAJB4 PPM1H VEGFB PIR CREBRF ITPKC KLHL24 PRRX2 ANKRD13A GALNT18 DENND5A SLC6A9 RNFT2 CACNG6 ASNS DNASE2 PCGF5 DLL1 MUC20 SLC1A4 TFRC ALDH3A1 CYP1B1 RTN4RL1 AARS IARS LINC01003 GYPC LPGAT1 METRNL TULP4 GARS CRIM1 XPOT TPRA1 FNIP1 TM6SF1 MIA2 ETS2 GPT2 PMAIP1 SLC28A3 HLA-DRA RRAGD VAT1 ANP32B KLHDC2 MDK C1S JADE2 PXK PIK3AP1 MSRB1 CNPY3 ALDH2 BLVRB EIF1 SERP1 CDKN1B BMF VLDLR-AS1 CBS PPTC7 PRKAG2 SESN2 CHST2 OSGIN1 GRPEL2 TRIM16L BACH1 APOE SPRR2E UBE2V2 SLC31A1 RIT1 TBXAS1 TNIP1 STX11 LARS CARS CLCN3 YARS XBP1 CTSF B4GALNT4 STX7 ERP29 TOM1 SEPHS1 HTATIP2 PHGDH CALCOCO2 SULF1 FAM32A MTRNR2L6 ALDH3A2 CHMP1B CCPG1 ACAA2 ANXA4 MPST PARM1 TTLL1 MED6 DGCR6L DDA1 HDAC5 TRAPPC6A GNPTG NUDT14 SMPD1 PANX2 HBP1 DKK3 TBC1D9 ITPR1 RPS6KA2 SELENOK PPARA GCLC FUT3 KEAP1 LRRN1 MEGF9 AZGP1 TSPAN15 TXNRD1 RRAS2 CNTNAP2 ZBTB21 GSR DAPK1 EIF4EBP1 ZFAND5 FBXO32 CYB561A3 NDUFA4L2 SLC19A2 TMEM106B MTHFD1L GPC3 TBC1D15 CYP2W1 GCLM ADH1B AKR1C1 LMO4 HAX1 RCN1 TNC AIFM2 SIAH2 SHMT2 HRK TOP1MT SEC63 CAVIN2 NOP53 SLC48A1 GPX8 SPSB1 ANTXR1 LHFPL6 MRPL23 FBXO2 SEL1L3 LPIN2 SPIRE1 TUBE1 KIF21B UHRF1BP1 TTC39B ADM2 AIF1L HS6ST1 PMVK TFCP2L1 CPE DOCK11 RSL24D1 PYROXD1 CEBPG BTF3L4 DGCR6 FBXO34 KIAA0232 ABHD14B DHRS3 DCAF11 CNST PSPC1 SLC20A2 AL355075.4 SNORA74A RNU4-2 SNORD3A MACROD2 TBC1D16 SNTB1 RETREG1 SNORD3B-2 CD99L2 SLC7A2 ADCY9 PHPT1 AGA KIAA0513 SLIT3 DDX49 PLA2G16 CCNY RHBDD1 LYPD6B B3GALT6 HRASLS5 YPEL2 SLC35A3 RORA ZNF394 RDH10 COA5 MPPED2 DCUN1D4 EIF2S2 ZNF419 KCNK15 ROM1 GUCY1A2 TCEA3 SHC2 SCARNA10 GID4 ARHGAP20 BEND6 MKX CEMIP2 CRBN KRBOX4 ZNF229 CBSL MPPE1 AKTIP DLK2 TMEM267 RHBDL1 CYB5D2 TMEM25 BOD1 BOD1 LINC00365 AC245100.6 CERS4 AC026785.2 SLC6A16 SINHCAF AL590617.2 AC010980.2 SNORD3B-1 FP671120.3 AP001207.3 FP236383.2 FP236383.1 AC007325.4 VIPR2 FP236383.3 RF00004 MIR3687-2 C15ORF59 NSMCE3 FP671120.4 ALDH1L1-AS2 C12ORF65 ARHGAP22 AC010536.1 LINC01836 IL36RN PRRT1B Top 500 upregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Mutant, 72 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/KihGJ72wk CEP350 RSRC2 RBL1 EGR1 EPB41L2 DDX58 DDX21 DAAM1 CXCL10 TMEM65 EP300 TMEM97 ETV1 NEDD9 RUNX1 KLF6 EHBP1 POLA1 NFKB1 BRD2 OAS1 TUBA4A STAT1 UBAP2L EIF2AK2 SLC5A9 PLAT OASL ELK4 FRMD4B CXCL2 ETV5 ISG15 LNPEP USP7 MX1 CHD1 RCOR1 ATXN2 SIPA1L1 NEO1 KMO SLITRK6 AUTS2 KLF5 HES1 MCTP2 NFAT5 GATAD2B PBX1 FOXP2 TNS4 RICTOR FAM83B QSER1 PRKAA2 APOBEC3A TET2 MUC16 MALAT1 TJP1 TFF1 PTPRZ1 KCNQ1OT1 ZNF462 NEDD4L FLVCR2 MYBL2 NREP IFI44 EPSTI1 BRCA2 MERTK BATF2 IGLV1-51 LINC00513 ZDHHC11B PTGS2 AC058791.1 RUNX2 EDN1 MCCC2 SFRP1 NAV2 STIM2 JAG1 HNRNPH1 MAP3K4 SOX6 TCF7L2 ERVW-1 MEF2A RSAD2 OAS3 IDO1 FBXO5 RGS1 CAMK4 BRIP1 IFIT1 IFIT3 IFIT1B OAS2 XAF1 COL24A1 USP18 CMPK2 IFIT2 CD19 HERC6 IFIH1 PARP9 SAMD9L HSH2D PARP14 FOSL1 SP110 RIMKLB SLC6A15 SRSF4 ZFP36 CYR61 FOS DTX3L IRF9 IFI44L SLC12A2 HNRNPUL1 MATR3 RBMS3 CCNL1 CYP2B6 TCF4 UBE2V1 EGR2 RGS4 IL16 KIAA1551 VAMP1 SERPINA10 TCERG1 TNFAIP3 HDAC9 CIART PLA2G4C MUC5AC TMEM213 DUSP6 LIF DUSP5 TIPARP SERTAD2 PPRC1 VMP1 BCOR SEC24B INTS6 CDC25B ODC1 PLEKHH2 NOP14 SETD2 SCAF8 HIVEP2 CEMIP C3ORF52 LRRN4CL TRA2B NAALAD2 AVIL PPM1K PP2D1 TRIM21 ZC3HAV1 TRIM5 BCL11A ELOVL6 PTMS NID1 CXCL11 ANKRD36B IFI6 FNBP4 IL32 PER1 TTF2 LAMP3 DDX60 MBNL3 NEB NOTCH2NL XRN1 HNRNPA2B1 MX2 IFIT5 HERC5 RBMX DDX60L SAMD9 SH3PXD2A-AS1 GBP1 PRRC2C ASH1L TP53BP2 PPP1R10 THOC2 RFX7 FOXC1 CD83 WEE1 AFF4 NFE2L3 PRRC1 SMCHD1 PHACTR4 CD44 DISP1 MEX3A ATF7IP CALB1 NR4A1 LINC00319 DCST1 NR1D1 SPRY4 TBX18 STAB2 GSN-AS1 ITGA6 RANBP2 SPEN SMG6 PPARGC1A GNRH1 AP3M1 NUP153 BHLHE41 CHST10 USP36 KIF13A CARD8 SUV39H2 HELZ ZBTB10 REV1 RBBP6 PTP4A1 ZNF326 CCAR1 HNRNPD RIOK1 PPP2R2A ARID1B BEST3 TET3 NEXN PLXND1 PRDM2 EPC1 MDC1 PPP1R12A ANKRD17 GSPT1 ACVR1C ZBED5 PER2 FOXP1 KMT2A KMT2C TMPRSS9 JMJD1C NF1 UNC5C ARHGEF38 ARSB CRTC2 SENP6 AQR UGT1A1 PPM1D ZKSCAN8 LTBP1 MLANA SFPQ TFAP2E KAT7 CCDC88A BCLAF1 LATS1 CDK12 CS POGZ SCAF4 RBM33 LYST SIK3 ARID2 CNOT4 WAC ZNF473 ELMSAN1 HIVEP1 NRM VANGL2 UBN2 TMEM131 ZNF608 CMYA5 CCDC14 ARHGAP21 ZMIZ1 TDG KRT7-AS HNRNPDL NCBP3 KAT6A GPATCH8 RPRD2 BAZ2B RBM5 TUT4 SOS1 EMSY TENT4B SOS2 EXOSC9 AC083837.1 ARAP2 ZKSCAN2 TENT4A ZC3H13 SYDE1 PPP2R3A RBM25 BAZ2A TMEM131L EPM2AIP1 INO80D RASSF9 FOXJ3 FMNL3 FMOD GAB1 ARHGAP26 ZMYND8 SRRM1 BPTF PROSER1 FTSJ3 CHAMP1 HMBOX1 CHD7 CLK2 ZDHHC16 AFF1 NPIPB9 PPP1R12B ATN1 YLPM1 SYCP2 SNORD25 MAPK1IP1L LRRTM2 AFF2 MYO9A CPSF6 LUC7L POP1 RBM26 RPP21 TAF4 BTBD18 MTMR10 NCOA6 NPIPB11 RGPD6 FBXW10 EYS NPIPB5 RGPD5 TRIM33 PAK2 RIF1 RUNDC3A SPDYE16 EGFL8 LRRC37B LBHD1 RGPD8 AC015813.1 ERVH48-1 INTS2 TBX6 SARS_COV2_ORF3A SARS_COV2_ORF1AB FAM86C1 SARS_COV2_S SARS_COV2_ORF10 SARS_COV2_ORF7A STK31 SARS_COV2_ORF6 SARS_COV2_E SARS_COV2_N AC012313.8 AP003064.2 AL139241.1 AC083843.3 AC011337.1 C5ORF63 SARS_COV2_M MUC19 C9ORF131 LINC00970 HELLPAR RNVU1-15 LRCH3 AC011374.1 ZC3H14 AC016831.5 PSMA3-AS1 SARS_COV2_ORF7B ZNF860 AL928970.1 AC092683.1 AP003392.1 CHL1-AS1 RNVU1-6 PKP4-AS1 NPIPB15 SSBP3-AS1 AL023803.2 AC025031.4 AC093690.1 AP001469.1 AP001528.2 AP003486.1 AL139289.1 SNORD63B CCDC192 PKD2L2 AL008729.1 PRICKLE2-AS3 PRDM5 FAM153A AC007038.1 IQCN AL031777.3 AL359924.1 TMEM202-AS1 RGPD4 AL512625.1 AC110813.1 AC016576.1 AC242022.1 LINC00843 AC007728.2 AC244021.1 SIAH2-AS1 U62317.3 LENG8-AS1 AC130650.2 TSC22D1-AS1 AC109587.1 AC138625.1 AC128688.2 AL359922.2 LNCSRLR AL021368.2 AMZ1 FAM153C SAP130 AL136985.3 ST7L AC004494.1 EVC2 AL136382.1 UBE2Q2L OR2A7 AC009812.3 AC100800.1 SLA2 LINC02569 AP006623.1 AC132872.3 AC097634.1 AC011595.1 AC000123.1 AC009962.1 AC090617.5 AL513327.1 ANKRD20A3 AP000322.2 SMCR5 AC012360.3 LAMB4 DTHD1 RBM15-AS1 ZNF207 LINC01833 NKAIN3 Top 500 downregulated genes in human nasal epithelial cells with SARS-CoV-2 infection (Mutant, 72 hpi) from GEO GSE162131 Bulk RNA-seq was used to study expression changes due to two strains of SARS-CoV-2 infection in human nasal epithelial cells. GEO Contributors: Gamage AM, ..., Wang L. Title: Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles. GEO Accession: GSE162131. BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/KihGJ72wk DCTPP1 UBL5 NBL1 FCGRT MVP FBXW5 MAP1LC3A COMT LMAN2 TSPO ESRRA RNPEP GALR2 ANXA3 YIF1A CRYBB2 RBX1 VILL KCNQ1 GPAA1 TIMM29 UBTD1 CTSD TST PLD3 USH1C FAU PEPD ELOB STOM AGPAT2 ACADS FRMD8 NEU1 SEPHS2 SMO H2AFJ SAT2 WDR34 NDUFV1 IPP DDAH2 RPL9 CCNO PITX1 WFDC2 KLHDC9 AC013264.1 RPL13A RPL39 RPS18 RPS29 STARD10 RPL31 RPS14 TAGLN2 BAX PTPA TMC6 RMDN3 DPP7 CHID1 XAB2 EMC10 FKBP8 QSOX1 CYBA CORO1B SLC16A3 ADGRE5 TMED9 FBXO6 TWF2 MRPL12 DDIT4 IGFBP2 AP2S1 H1FX SNAPIN MYDGF LGALS3 CLDN7 DEPP1 SNORD3C MIR3648-2 MIR3648-1 ADGRB2 CDKN1A BAD B4GALT7 ABCC6 CRB3 SPINT2 ADAP1 LTF CLDN4 THEM6 CYB561 PPP1R16A CLDN3 GIPC1 SLC2A4RG SLC52A2 EEF1D RHOD TMSB4X SLC9A3R2 INSL3 PWWP2B SLC12A7 PITPNM1 TMEM8A TNFRSF18 DNPH1 HBB MDFI INHBA PTPRT PSENEN RPS28 LRFN4 PLTP SMDT1 PSMB10 SIPA1 ID3 CLIC3 NDUFA3 MED18 CHCHD2 RPL3 RPS19 SNX17 RPS5 RPS21 CTSH PRDX5 PSMB5 LAPTM4A TMEM160 GSTA3 NDUFB11 CD74 RPS9 NDUFB7 PEX6 LYPLA2 RPL18A STUB1 JTB EVA1B ROMO1 PSAP ATP6V0B MRPL28 CDIPT FAM53B SMIM22 MXD4 CTU2 IGFBP7 LBH PSKH1 ANXA1 NUDT16L1 GUK1 CHCHD1 ACYP2 CD151 SCAND1 COX14 PGLS RRAD KCNF1 OLFM4 LYPD2 VASN DLX4 PROC SERTAD1 MRPL34 EMC4 TXNDC17 ATP6V0E2 CIB1 RBM42 C19ORF70 TMEM208 CUTA C12ORF57 PSMB3 ZNHIT1 DPP3 C19ORF33 LSM7 UQCRQ DCTN3 NOSIP POLR2E COMMD8 SSR4 PSMA7 CMC1 RPL29 BBS5 MAD2L2 CHTF8 SF3B5 ETFB C1ORF122 TAX1BP3 YDJC VPS51 WFDC3 PRR15 B3GALT4 ORAI1 PRRX2 SMIM1 GALNT18 BCL2L12 CACNG6 GSDMD CCDC153 SLC16A12 ZMYND10 SSNA1 HLA-DOA C19ORF25 ISOC2 MAP1S SLC43A2 UTS2B C6 CDC42EP5 GALNT11 CYSRT1 TPRA1 DEGS2 SNHG9 OXTR HLA-DRA PMM1 GRAMD1C VNN2 MVB12A BPGM SERF2 MSRB1 COPE ARPC4 PDXK RNH1 KLHDC8B RASSF4 SPRR2E SAA2 ELFN1 ANAPC11 RGS19 TRADD B4GALNT4 ARRB1 MRPS12 TOM1 PPP4C NR1H2 BAK1 SMPD2 FADD SYAP1 NUDT8 CHMP1A AURKAIP1 C9ORF16 BST1 ALDH3B1 LGALS7B MPST ABHD8 NUBP2 C19ORF24 NACC2 HSPB11 SPNS1 ACTR1B FBXW9 MZT2B ZNF524 PGPEP1 DGCR6L GPRC5C ITPA APC2 RABEP2 TRAPPC6A POLE4 KIRREL3 NUDT14 SLC39A13 FDXR RNPEPL1 SMPD3 PRADC1 MBD3 RPS19BP1 FASTK TMEM129 REPIN1 PQLC1 TIMM13 GAS6 TSSC4 SIVA1 PEX5 AP1S3 TNIP2 PLIN3 PLEKHF1 YIPF2 PLXNA1 FXYD3 TSPAN15 CDH11 LRWD1 HSF1 ATP2A3 BIK POLR2F ARSA CYB561A3 CYP27A1 IVD STK11 ATP13A2 SLC47A2 CPTP RRAGA CYP39A1 MRPS26 ADH1B RIDA PIN1 RPUSD1 FAM207A AKR7A2 ENDOG NOP53 TMEM59 TMEM14C SELENOH DNASE1L1 CYB5R1 MRPL23 JOSD2 POLR2L TOMM7 CAPS COMMD4 C7ORF50 LAGE3 MRPL41 PMVK HES6 TMEM141 NTHL1 GAMT THAP11 GNA15 KIAA1211L HYAL2 ZDHHC12 DGCR6 NR2F6 TMED1 MACROD1 ALKBH7 FAM98C WDR18 OXLD1 ECI1 BOK NME3 PDLIM4 PPP1R3F REX1BD DDTL SLC20A2 AL355075.4 MRPL57 COMMD5 TMEM9 SNORD3A MINCR SNORD3B-2 HDAC11 LAMTOR4 BPHL HIST1H4J PEX16 PECR PKN1 HIST1H4K RMRP PHPT1 ST6GALNAC4 TSPAN9 DDX49 CACFD1 PLA2G16 MFSD10 ABHD17A PLA2G10 RASSF7 TMEM98 CLP1 TSC22D4 SNORD94 FNDC11 CRNDE TRABD LLGL1 TSR3 C4ORF48 CCDC22 PUF60 TMEM132A LYNX1 HAGHL CSNK1G2 FLYWCH2 ZNHIT2 C21ORF2 B3GAT3 BCDIN3D MRPL58 CXORF56 MCRIP1 MCRIP2 NUDT18 ADCK2 MIEF2 DLK2 PSMG3-AS1 CYB5D2 GATD1 BX255925.3 AL356488.2 CERS4 ZNF135 SNORD3B-1 AP001207.3 TUBA4B AC007325.4 TMEM101 NELFB TMEM125 AC005790.1 MIR3687-2 AC009237.14 MIR3687-1 DEF8 TERC SAYSD1 CHCHD5 PIP5KL1 TMEM250 AL121790.2 ZNF837 AC092171.3 TEDC1 NHLRC4 AC004556.1 AIFM3 STOML3 ANKRD65 POLR3GL AC036176.1 AC068305.2 DYDC2 LINC02298 R3HCC1 AMY1C PPP4R1-AS1 AMY1B FAM27C B9D2 AC133555.3 BCAS4 AL358075.2 AC007405.3 AC121338.2 AL512625.2 TMEM102 MIR200CHG AMY1A WDR25 CFAP97D2 C2ORF50 CYREN Top 500 upregulated genes for SARS-CoV-2 in human colon organoid from GSE148696 Transcriptomic analysis of stem cell-derived human colon organoids was used to study SARS-CoV-2 infection via bulk RNA-seq. GEO Study Title: Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids. GEO Accession: GSE148696. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/4nbuj25Yb IL1B BIRC3 HSPA5 CCL2 TMEM37 EGR1 UBD SPINK1 TNF CXCL5 ITGB1 DDX58 UGT2A3 YWHAZ IL1A CXCL10 DPY19L1 TLR4 TPM4 ANXA3 SEPP1 TMBIM1 ZCRB1 ANXA2 ACSL5 NEDD9 ADAM9 GNG5 PMEPA1 KLF6 TUBA1A CTNNB1 NCK1 HMOX1 MTMR11 BIRC2 PLOD2 CLIP4 B2M HERPUD1 PLAT MUC17 MARK1 HHLA2 FRMD4B CXCL2 C17ORF78 PLS3 CAT MAP3K1 ARL14 CSF2 AP4S1 VLDLR KLF12 ARHGAP18 CD55 CHMP2B CAV1 OCIAD2 CEACAM6 CP CXCL1 CXCL6 KRT18 ITGA2 TNFSF10 PERP KRT7 ZNF532 RGS2 TM4SF1 TTC9 SLC40A1 HIST1H2BC GULP1 GCNT3 S100P DUOX2 OSMR RASSF6 MARCKS DLGAP1-AS1 RND3 ADAM28 INPP4B TFF1 FOXQ1 SGPP2 GPRC5A CEACAM5 S100A2 MBNL2 TACSTD2 ISG20 LCN2 KRT8 TPST1 ZBTB20 DHRS9 APOL1 TGFBI PROS1 B3GNT7 UNC13D ITGA5 EMP3 RHOB NET1 SDC4 CAPG ME1 POMP ANXA2P2 ELL2 LGALS1 ANXA5 BLVRA EPSTI1 RRAS IL18 C2 LGALS3 CDKN2B RASGEF1B ITGB8 AKR1C3 TCN1 AKAP12 ARFGAP3 TRAM1 ZFP36L1 KLF10 SLC2A3 MMP1 PIK3IP1 EDN1 PLAUR ACOX1 GJB3 CELSR1 KRT80 TMSB4X DKK1 STMN2 FOXL1 ODAM ATF3 MSX2 EFNB2 TNFRSF11B TPBG CFB ECT2 LPXN CTSS TNNT2 BEX1 C3 CXCL3 KYNU IFI16 MDFI PTAFR PLAC8 NAV3 CPNE5 VCAN SOCS3 GBP2 CASP4 SERPINA3 UBE2L6 ANGPTL4 PLAU SP110 NDP EPHB6 CD59 ETS1 IER3 FOS MAP1LC3B IRF1 SGK1 MYL12B MYL12A ICAM1 NFKBIA KLHL5 CLDN18 IRF9 CLIC5 GBP3 SEMA3C CTGF WBP5 S100A4 SERPINE2 PDE5A RAP1B SERPINB9 S100A6 ARRDC3 VIM ERRFI1 RAB11A IL2RG CYP2B6 FEZ2 DSTN LBH FNDC3B FSTL1 ANXA1 RBM7 SAT1 NDUFV2 GTF2B SEC61G S100A10 BNIP3L CREB5 TGFB1I1 RAB30 B3GNT5 TNFAIP3 HDAC9 IL23A FILIP1L S100A3 GDPD1 TIPARP BAMBI SERTAD1 BHLHE40 SGCE MMP10 ATP6V1E1 S100A11 LYPD1 ARL6IP5 TCEAL8 ATP6V1D YPEL5 PSMD10 LINC00152 VMP1 CAP1 KCTD9 TUBB6 AMIGO2 NEK7 MORC4 MXD1 MALT1 SLCO2A1 VAV3 PLEKHH2 DNAJB9 DUSP10 ETNK2 KLF7 C15ORF52 ID1 EFNA1 ADRA2C TBL1XR1 GSPT2 RNF19A PIR TMEM139 HABP2 C15ORF48 RND1 ITGAV CD47 SHROOM4 VAMP5 VRK2 GCA SPPL2A TRIM69 MORC3 CTSE CXCL11 PRSS2 VNN1 IFI6 PRSS1 CRABP2 IL32 CFI CEACAM7 NHS AHNAK2 SP100 MIR22HG BCL10 IFIT5 DDX60L SH3PXD2A-AS1 GBP1 PSTPIP2 LIPH LAMC2 PRKACB EMP1 CEACAM1 PLK2 NCEH1 GPR115 SOD2 PARP8 SH3KBP1 IL7 OPTN C8ORF4 RAB8B SERPINA1 LPAR6 ACTR3 HOXC9 BMF HRH1 KRT6B EGLN3 IL1RAP SERPINB8 MIR4435-1HG SEMA7A STK17A LAMA3 COL12A1 ITGB6 TUBB3 SPOCD1 PLSCR1 ADAMTS9 DUOXA2 NCOA7 SLC6A14 PTPRR C12ORF36 IFNGR1 IFNAR2 RIOK3 UGT2B7 CASP5 PPARGC1A TAX1BP1 GNRH1 IFNGR2 YIPF1 UGP2 SH3GLB1 TNFAIP8 POLD4 SQRDL GDE1 OTUD1 PIK3C3 GALNT1 CDC42 CMTM3 ACAA2 GPR110 KTN1 VEZT USP53 PDIA3 PON2 P4HA1 TMCC1 ATP9A MYEOV SLC9B2 JAK3 HBP1 NES FAM214B ACOT9 SRPX2 MMP7 INSIG2 ECE1 MPDZ SLC2A12 SRD5A3 PDGFB PGM3 CCNG2 P4HA2 IFT57 ANKAR ZNF396 PROX1 ATG4A RNFT1 TFPI TMEM106B RAB7B DNAH5 GPR137B SLC16A4 SERPINA4 LAMA4 INHA DNAJC15 ALDH1A2 RHOC SDCBP GPX8 DSE DTNA LYST SKIL L1CAM ADM2 MAOB CSGALNACT1 GJB4 KCTD11 LCA5 CCDC121 NMRK1 CD109 MSANTD3 DOCK11 QPCT HSPA13 CAPRIN2 IDS RASA2 C12ORF49 ZNF222 GPR161 SOS2 ARL4A CCDC69 PID1 RASSF9 PDLIM7 TM4SF18 PCMTD1 RBP1 PDE6D RNF186 TPK1 SESTD1 LOC100506098 TSPAN2 LINC00941 SEC22A BLACAT1 NUDT4 FAM134B ERO1L PNPLA8 TWSG1 ZDHHC2 PGM2L1 KATNBL1 IL8 POC1B NPHP1 RP11-277P12.20 VIM-AS1 TMEM217 LINC01138 KIAA1841 FAM227A MOSPD2 CBLN3 CTTNBP2NL MYH15 TMC7 DNAJC28 BBS9 ZNF214 LOC100288175 LINC01124 C8ORF47 C1ORF180 C5ORF54 FKBP9L FAM132A LINC00623 CASC9 LOC102724608 LOC100862671 PVRL4 C10ORF118 LOC100506990 TRNS1 C12ORF4 KRTAP5-1 C7ORF31 TMEM66 LOC100507634 Top 500 downregulated genes for SARS-CoV-2 in human colon organoid from GSE148696 Transcriptomic analysis of stem cell-derived human colon organoids was used to study SARS-CoV-2 infection via bulk RNA-seq. GEO Study Title: Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids. GEO Accession: GSE148696. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/4nbuj25Yb MAOA NUP210 FOXRED2 TM4SF20 GLYCTK XPO6 ABCC1 ANPEP CYP3A4 MDN1 LARP1 PFAS SI GUCA2A RBP2 MYO1A SLC13A2 GPT ABL1 ISX ING5 CDX2 PRRC2B VIPR1 SLC9A3 CDX1 HNF4A SLC7A9 BAIAP2L2 DMBT1 ANXA13 FABP6 TREH ST6GALNAC1 SLC5A9 CLCA1 MEPCE PCNT ALDOB TLN2 EPHX2 ASAH2 FCGBP IGSF9 STC2 VWCE METTL7A FZD5 CPT1A PIGR RN7SL1 EXT1 FGFR2 RNF152 KIAA1324 ADH1C GSTA1 KCNQ1OT1 SLC25A23 ARID5B SYBU C2CD2L SLCO2B1 ATG16L2 PDCD11 ACSS1 STEAP3 AKAP1 GIGYF1 CAD NDST1 FLVCR2 SNX32 E2F2 MARVELD1 KIF18B ITGA7 STARD13 FGD2 SLC1A3 EIF4G1 RGS16 SLCO4A1 EPHB2 PPARGC1B DUSP7 FAM20C UNC13B TRIM71 KCNMA1 ESRP2 LGALS9C LGALS9B CDKN1C SPON1 PTGDR TGFBR3 ABCC8 PLCXD1 MYC NOTCH1 ABCC2 SNPH FAM20A INS VPS9D1-AS1 FOXM1 EPN3 DNAJA3 COL1A2 INPP5D FRZB FRAT2 HERC2 ATOH1 CACNA1H SOX12 CBX2 C2CD2 SYNPR CCDC85C KMT2B RGL2 GPBAR1 PRR12 GSG2 RAB37 RETNLB GFI1 GP2 GPR55 PREX1 POLE KCNJ3 SLC7A8 HEPACAM2 ALDH1B1 AMBP TMEM171 PIM1 AIM1 ZNF704 DDC CD200 ID3 TSPAN7 IHH FAM53B SELENBP1 ZNF692 MYO18A ANK1 PDX1 PDZRN3 ASCL2 STARD9 ALOX12B SYP GPRIN3 DNAH1 SYNGAP1 GSTA2 CCND2 CYTIP CITED1 TMEM52 SNHG15 TP53I11 TTR NEUROG3 ADRA2A SEC31B LGALS2 PAPD7 IRF2BPL PPRC1 SOWAHC GYS1 FAM216A SLC29A1 PFKM ERVMER34-1 CHST6 ODC1 GNAZ AOC2 MAP1B ZNF618 AKR1B10 EID2B TMEM200A CDCA7 MLXIPL HSD17B14 SLC6A9 CELF3 AGMAT PPM1K ASB13 DLL1 RCOR2 WDR90 TMEM229B SLC6A4 MSI1 FCAMR SPATA25 NPIPA1 ADRB2 MLEC KCTD12 GLIS3 CNNM3 KBTBD6 TULP4 CORO2A SRRM2 CD44 SKIDA1 SMOC2 PRR22 C10ORF2 NT5DC3 PLA2G4F CD70 FANCA ADH6 PDCD4-AS1 TGFB3 DDN KIAA1244 RNF135 MTSS1 SEMA4D PLA2G6 DOK3 DOT1L CYP2C9 TERT CA12 TGFBRAP1 IFITM10 PRKCA BDH1 VTN ERN2 USP36 SLC12A8 HIRA SPINK4 ZNF8 SUSD2 ACAP3 ABCB6 COL27A1 MLXIP UCKL1-AS1 SMPD3 POLR2A PTPN18 EPHB3 ATP7B RAPGEF1 MDC1 SNAI1 SRCAP ADCY6 RSAD1 LRIG1 DHX33 MFSD7 APLN PPARA GP1BA LIPC APOC3 ADCY1 MUC2 SEMA4G PER2 CELA3A LMTK2 CLCN2 ARID1A UBTF KMT2C TRPM4 RALGAPA2 SHROOM3 SYT7 WNK2 HECTD4 CAMKK2 SST NPIPB4 TNPO2 GCG ABCA3 CAMK2G SCARF1 RAB26 CYP2C19 PRKCG ABCA2 MTA1 HUWE1 TRIM35 SLC29A2 ALOX12 SLC23A2 MYB RRBP1 CREB3L1 PPIF PPP1R1B SDCCAG3 PELP1 MYBBP1A GEMIN4 TCOF1 AFP SP2 CELSR3 ATXN2L TANC2 NEURL4 BAHCC1 GSE1 SLC25A37 PKDCC HES6 PCYT2 AGFG2 MPV17L MAP7D2 ZBTB7C FAM84A ANKMY1 NCR3LG1 SRGAP3 HCFC1 PDE3A ZCCHC14 SZT2 SPATA13 RAD54L2 ZNF592 RGMB RN7SL2 TBC1D16 KMT2D ZHX3 CUL9 TTC28 KCNV1 ANKS6 CD99L2 PALM3 ACOX2 PRLR SLC7A2 AMT SIDT2 PRRC2A DGKD CCDC88C VAV2 CDK5R1 NID2 KIAA0513 MGAT5 ACACB FRMD4A ADARB1 PYCRL PDXP GOLGA2P5 ADCK3 ZMYM3 APBB3 AATK C1QL1 NAT10 PRKX CABIN1 FAM46C MPP1 SMIM14 CHD7 POM121 WNK4 POFUT2 PTPRN CAPN3 GATAD2A PTPN23 WBSCR27 MINK1 FOXD2-AS1 ADCY3 SOGA2 PAQR7 RCN3 HOTAIR BSN PKD1P1 SPATA18 HAGHL CHERP ENGASE FEV RP5-1033H22.2 LOC101928527 FAM86HP ZNF512B AQP7 OXER1 SLC43A1 MAMDC4 DAGLA LOC102723845 RAB17 PCSK4 CYB5D1 GNAO1 TENM4 SLX4 AMER1 TAF4 NCOA6 POM121C NPIPB5 FOXD2 ARHGAP33 IQSEC1 RUNDC3A NPIPA5 PLEKHG4 MOCS1 DLK2 TYW1B SCART1 NRIP2 LINC00261 DACH1 CDK20 TMEM25 PLA2G3 SNORD49A RGMB-AS1 LOC100130744 LOC101928588 LOC90784 MGC27345 LOC441528 MTL5 INSM1 CTD-3080P12.3 EFCAB4B KIAA0226L LOC101928706 ZIC4 LOC101928192 WDR59 LOC100505727 LOC642846 LOC100288152 LOC100288123 STAG3L5P-PVRIG2P-PILRB ABHD16B LOC101927104 KIF19 LOC101060494 CHST5 LOC101929442 TSSK6 CCDC183-AS1 LOC101929145 SNORD78 NXPH4 MFI2-AS1 SNORD35A MCIDAS CCDC135 ANGEL1 GALNT8 LOC101927187 C9ORF172 FER1L6 LOC101930307 DOC2A LOC101928862 RPL19P12 LPHN1 LOC100288778 LINC01002 SNORD81 NEURL1 LOC100506860 NFASC Top 500 upregulated genes for SARS-CoV-2 infection in human cornea from GSE164073 Cornea was isolated from human donor tissue and passaged in tissue culture. Cells were infected with SARS-CoV-2 for 24 hours in triplicate and the host response was compared to mock-infected samples. GEO Accession: GSE164073. GEO Title: Response to SARS-CoV-2 infection in cornea, limbus and sclera from human donors. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/PPtoLnDe6 IL6 GDF15 DPP4 COL6A1 ABCC1 ANPEP VDR CXCL5 DDX58 LSAMP MYO1D ABL1 NDRG1 PMEPA1 SPTA1 FN1 ADAM17 TRAF3 MGAT4B CRTC3 CXCL2 STC2 PDE4DIP VWCE KDR METTL7A CACNB4 ACO1 SH3D19 CXCL1 CXCL6 TSHZ2 OLFML2B RBPMS REPS2 CGNL1 NEK10 LRIG3 PPL PNRC1 KIAA1324 TCP11L2 PTGFR SATB1 ANKRD33B SETBP1 SSBP2 EYA1 CCL8 KIAA1671 ABLIM1 SLC25A23 SYBU TNFAIP2 PARP10 ARHGEF10L NUMA1 TBC1D2B GAA LRP1 NRP2 SLC6A6 LDLR CORO2B FADS1 GPNMB SLC1A3 MAFB EPSTI1 UAP1L1 CDKN2B OLFML2A MMP19 SH3PXD2B PTGFRN SCD SGCD ITGB8 PTCH1 G0S2 LAMA2 MSC COL6A2 TFDP2 TGFBR3 ZFP36L1 KLF13 KLF11 PIK3IP1 FAM20A COL14A1 AGRN KIAA1522 MRO RHOU SORCS2 CLU PRICKLE1 ABI3BP EDNRB JAG1 RSPO1 TRIM8 TAB3 GLIS2 CFB TNFSF14 GPR176 CTSS BVES FABP3 LACC1 CYP7B1 C3 CXCL3 CH25H APOL6 COL24A1 C1R COL3A1 TNFAIP6 CACNA1G PML NAMPT GBP2 SAMD9L GCH1 NFIL3 PIM1 FAP SLC39A14 TLR3 PLAU UBA7 GAL3ST4 ITGA8 IGDCC4 TRIL EPHB6 TTYH3 FTH1 DPYSL2 KLF4 IRF1 HMGCS1 ICAM1 NFKBIA KLHL5 TJP2 SEMA3C DRAM1 PDGFRA OGN BTG1 MGP TAPBP DDR2 JUND TP53INP1 TSC22D3 ZBTB16 PDPN MKNK2 TNS3 C1ORF198 FASN CTDSP2 MEGF8 COL6A3 ANK1 PDZRN3 POU2F2 GLI3 ZC3H12A RGMA IL16 CSF1 SRPX TRIM22 RORB VAMP1 CCND2 HMCN1 TNFAIP3 NATD1 HIC1 SPOCK1 NTNG2 PLA2G4C CLSTN3 TG VASN UNC5B SEZ6L2 CLN8 TP53INP2 PLA2R1 IRF2BPL NFKBIZ CDC42EP3 FOXO3 TNFRSF21 LAMB1 MXI1 PCSK5 MXD1 CDC25B MN1 COL7A1 TMEM170B ZCCHC24 VEGFB INSIG1 CREBRF MSMO1 HMGCR SQLE KLHL24 FAM129A MCC COL11A1 GXYLT2 MVD SLC6A9 LRRC15 MFAP4 ITGA11 SLFN5 TLR2 GJD3 MAP3K8 PTGDS IRAK2 IRX1 ANKRD13B CYP1B1 NID1 PCSK9 SLC43A2 NTNG1 ANKRA2 IL32 SPATA25 APCDD1 AHNAK2 UCN2 GLIS3 RELB BTN3A3 CX3CL1 BTN3A1 C1S SOD2 OPTN CFLAR PDXK ADD3 KANSL1L SOBP RASSF4 IL17D SESN2 LPIN1 XYLT1 DNM1 ZBTB47 ITGB3 MMP2 RASL11B DPYSL3 SCN2A SAA2 NUMBL MEGF10 CXCL12 PLXNA4 IFNGR1 BDKRB2 TNIP1 HLX NANOS1 SMG6 PPARGC1A CA12 FAIM2 MMP14 NFKB2 SC5D ARRB1 PLBD2 TNFAIP8 CD82 OTUD1 FBLN1 CYLD DENND2A CCDC92 CALCOCO1 ACKR3 GPR1 TBC1D17 TPCN1 EPHA4 C14ORF132 CLDN1 PNMA2 SLC39A8 KLHL21 PGPEP1 PLEKHM1 PTCH2 LSS ZNF219 FAM102A RNPEPL1 PANX2 CRTC1 PCDHGC3 ZFYVE26 CLEC1A CYP19A1 ACSL1 YPEL3 CHI3L2 TPP1 PXDN HBP1 PDGFRB ABR LRIG1 RPS6KA2 ELN SOD3 IGF2R MTHFR CPM SREBF2 GAS7 NPAS2 FOXP1 STEAP2 SLC22A3 ARHGAP32 ENOX1 SLC2A12 BACE2 AMOT RUNX1T1 CCNG2 CBX7 ABCA9 TMEM119 COL10A1 BCL2L11 SLC9A9 ZFYVE1 FAM133B FBXO32 LUM PRKN NCAM1 IL17RC CYP51A1 HTR2A ADH1B SLC23A2 SLC16A2 INHA CREB3L1 AKNA SLC11A2 SUSD6 COL16A1 ARHGEF2 DTNA SLC35E2B PCNX2 SH3RF2 WTAP TIAM2 ADM2 NRCAM DHCR7 STXBP6 TRIM47 LTBP2 NFIX SDCBP2-AS1 SULF2 FAM43A STON2 UST CD109 FADS3 ECM2 APBB2 GFRA1 ANK2 ZMIZ1 PTPRK SVIL KIAA1549 ATP6AP1L MIR193BHG HECW2 SNX33 RIPOR3 MACROD2 TBC1D16 PPM1L SLC41A2 PRG4 C1RL EDA2R MAPK8IP2 NID2 P2RX7 KIAA0513 MAN1A1 SLIT3 LOXL1 SYNE3 COL5A3 RALGPS1 IFT140 FAXDC2 YPEL2 FOXN3 RAB11FIP4 EBF1 EFNB3 DGLUCY ZNF358 TMEM132A IQSEC2 GPRC5B LINC00476 SPIN3 ZNF362 CNTNAP1 WASF3 ANGPTL7 ENDOV ZBED3 ARHGAP20 CLIP3 FSTL5 SDK1 IQSEC1 ST8SIA1 FAM110B ARHGAP28 ACVR2B AKR1B15 CLDN11 FREM1 DBIL5P CTIF MAML3 EVC AFF3 ZNF521 WASHC2A TMEM132B ASPN ADGRA2 COQ8A ADAM33 LYPLAL1-DT LINC01239 FKBP9P1 NMRAL2P SNX29 LINC00674 LOC389641 CACNA2D4 CASTOR3 LINC01772 OPRL1 FIBIN ZNF423 LINC01102 PAPPA2 LOC100506544 LINC02015 MSC-AS1 VMAC LINC00607 TMEM268 SBF2-AS1 RPSAP52 APCDD1L GUSBP4 GAS6-DT PCBP3 RNF150 SNORD159 SNX21 LOC100129940 LINC02256 Top 500 downregulated genes for SARS-CoV-2 infection in human cornea from GSE164073 Cornea was isolated from human donor tissue and passaged in tissue culture. Cells were infected with SARS-CoV-2 for 24 hours in triplicate and the host response was compared to mock-infected samples. GEO Accession: GSE164073. GEO Title: Response to SARS-CoV-2 infection in cornea, limbus and sclera from human donors. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/PPtoLnDe6 NDFIP2 SRP19 ADAMTS1 HDAC2 UHRF1 RBL1 EGR1 PRIM2 PFAS KPNA2 EIF2S1 DDX21 EZR PVR NEDD9 CENPF NUP58 HSP90AA1 ERG POLA1 DNMT1 TUBA1C PSMC6 PLOD2 NCKAP5 PDE4D PRIM1 BRCA1 EPB41L3 PLAT NUP88 NSD2 YWHAH FAM72B CDK2 PGM2 LRRC40 PITPNC1 ARHGAP18 PSMC3IP DDAH1 RGS2 TM4SF1 FGFR2 NR4A2 DSG2 H19 C12ORF75 CKS2 GPRC5A STMN1 SH3TC1 PLK1 EXO1 GAS2L3 MYBL2 TOP2A ZWINT CDCA8 CCNA2 CLSPN EZH2 LMNB1 CCNB2 GTSE1 CDKN3 UBE2C KNL1 AURKB E2F2 NEK2 SHCBP1 KIF18B NUF2 DEPDC1B CDCA5 HMMR SPAG5 BUB1B MCM2 WFDC1 KIF2C CDC25A KIF14 KNSTRN ASPM AURKA DLGAP5 ESPL1 BUB1 RRM2 CDK1 PAQR4 CDC6 E2F1 BIRC5 ORC1 POLQ KIFC1 KIF4A SAPCD2 SH2D4A CCT8 MCM10 KIF15 PRR11 CDCA2 KIF11 TPX2 STIL CCNB1 ANLN NCAPH CEP55 CDCA3 CDC20 KIF23 PKMYT1 SKA1 HJURP TRIP13 CENPU CENPW TTK MKI67 CDC45 KIF20A DTL NCAPG TYMS CXCL8 IL7R NOG CEP78 A2M MYBL1 LINS1 TRAM1 CKS1B BDNF EDN1 CYCS FOXM1 PSMD6 WWC1 DKK1 FZD4 DCK TNFRSF11B CBFB PRC1 CENPK CENPN ARHGAP11A CDC25C E2F8 UBE2T CENPA MTFR2 RAD54L ESCO2 SPDL1 EME1 FANCI ASF1B KIF22 TCF19 CHEK1 RAD51 GINS2 DUSP2 CKAP2L CHAF1B IQGAP3 PARPBP FAM83D FANCD2 SKA3 NCAPD2 SPC24 DBF4 ECT2 TACC3 ERCC6L NUSAP1 CKAP2 MCM5 PBK TOX CENPI BORA RACGAP1 AUNIP SPC25 KIF20B MELK ZWILCH H2AFX TRAIP DEPDC1 MAD2L1 CCNF NCAPG2 HMGB2 NDC80 INCENP CENPE NEIL3 RAD51AP1 CDT1 POLE2 GINS1 CHAF1A KIF18A CCNE2 XRCC3 NEFH DHFR TIMELESS DIO2 HPSE MAMDC2 SORD ACTC1 CYR61 SGK1 TGM2 ID3 GATA2 CA2 CTGF FABP5 H2AFZ CCT2 LIMCH1 ALDH1A1 PSMC2 ABRACL NPR3 HSPH1 TUBB2A LBH LXN PHLDA1 GNG11 SRSF3 VBP1 CACYBP DEK ATOH8 RGS4 SULT1E1 MYPN SOCS2 HMGN5 DUSP5 ZNF367 BAMBI IL11 UBE2S HAT1 HMGB3 CMSS1 RRM1 RNASEH2A PTTG1 HMGB1 UBE2N MRPL13 TEX30 TIPIN MAGOH EBNA1BP2 TPRKB NOP58 ACTL6A ANP32E PCNA CORO1C MSH2 UCHL5 VRK1 NUP37 CDC7 SSB RFC4 FAM107B BZW1 PSMD14 LACTB2 NOL11 TMPO PNPT1 MRPS30 GMNN NUP107 TUBB6 NUP93 TMEM50A ETF1 SUCLG2 TCP1 ODC1 HSPD1 PDE4B DLAT SKA2 ARL6IP1 ID1 SRSF7 PRRX2 DIAPH3 CSE1L ATAD2 SLC35G2 CDCA7 FANCG MCM6 ITPRIP TRA2B GSTCD FEN1 GRP VMO1 TMA16 TMEM132D MCM4 SLC20A1 FAM111B MCM7 DIRAS3 WDHD1 SNRPA1 RFC2 MIS18A LMNB2 APOBEC3B LIG1 NCAPD3 HNRNPA2B1 PAPSS2 CRIM1 RFWD3 LIMA1 PLK2 RCAN1 CTNNAL1 NUDCD1 NCEH1 CHSY1 SRGN NRGN HMGN2 SNRPB2 GAS1 FJX1 GREM2 MCAM PLSCR1 FANCA HPD UBE2V2 COLEC10 HPRT1 GNPNAT1 FARSB HAUS8 DMC1 CHMP1B ARMT1 CCT6A GGCT SUV39H1 XRCC2 LTV1 LINC00473 DNAJB11 PTP4A1 EIF3J SNAPC1 BRIX1 HERC4 SMS PPAT CDH4 CTPS1 NASP SPHK1 PUM3 ID4 INHBB SMC4 CIP2A PCLAF CMKLR1 NRAS MTHFD1 RANBP1 SLC16A4 OSBP2 SFPQ MYB SGO1 TNC MCM3 MET LIN9 UTP3 NUDT15 NUP205 TRMT6 TMSB15A HNRNPAB POC1A CENPO CDK7 NOLC1 CSGALNACT2 TIMM17A SMC1A UBASH3B GINS4 DARS2 DUT ADGRG6 GTPBP4 PSG4 RIBC2 CSGALNACT1 EPGN ENDOD1 SSX2IP PCDH7 LRRC8C SAMD11 RFC3 DNAJC9 DDIAS NECTIN3 PBDC1 GALE JPT1 PFKP SNRPD1 HNRNPA3 EXOSC9 SGO2 C1GALT1C1 MZT1 SPA17 HNRNPR PIMREG PSMD12 SLC7A2 HNRNPH3 ACAN SHC4 G2E3 PLK4 RPS6KA6 CEP128 LARP4 NUS1 NDNF MCM8 DSN1 LYAR KIF24 BLM WNK4 PAK1IP1 FANCB AK5 ARSJ MAPRE1 FAM98B POP1 CSTF2 GINS3 NDC1 LY6K DAW1 TRABD2A SCG2 P3H2 BAG2 WDR76 TEDC2 HASPIN ERI1 LINC01503 STAMBPL1 LINC02432 COQ3 LINC02104 SCLT1 SHISA3 GMNC SMIM2-AS1 LINC01085 Top 500 upregulated genes for SARS-CoV-2 infection in human limbus from GSE164073 How Related: Limbus was isolated from human donor tissue and passaged in tissue culture. Cells were infected with SARS-CoV-2 for 24 hours in triplicate and the host response was compared to mock-infected samples. GEO Accession: GSE164073. GEO Title: Response to SARS-CoV-2 infection in cornea, limbus and sclera from human donors. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/GAx5ZhYyF CEP250 UHRF1 BIRC3 IL6 DPP4 CCL2 ANPEP CTSL SQSTM1 VDR CXCL5 VHL MME CENPF CIT NFKB1 PTX3 TP53 ADAM17 TRAF3 PRIM1 BRCA1 AGTR1 CXCL2 HS2ST1 BDKRB1 FAM72B MX1 VWCE KDR AFAP1L1 LIFR ARHGAP18 METTL7A TRIM37 ACO1 BCL2 MT2A CXCL1 CXCL6 TSHZ2 ASS1 TM4SF1 REPS2 CGNL1 APLF PTGFR CKS2 TPST1 TNFAIP2 LSP1 PARP10 PGD APOL2 ABCC3 SLC6A6 PLK1 GAS2L3 DHCR24 MYBL2 TOP2A CDCA8 TK1 TROAP LMNB1 CCNB2 GTSE1 CDKN3 UBE2C KNL1 AURKB GLRX SHCBP1 LDLR KIF18B NUF2 CDCA5 HMMR SPAG5 FKBP5 BUB1B STARD13 PDGFC KIF2C KIF14 ASPM AURKA TIMP4 DLGAP5 FADS1 BUB1 RRM2 SLC1A3 BIRC5 POLQ KIFC1 KIF4A EPSTI1 SAPCD2 HGF UAP1L1 CARD6 MCM10 RGS16 PRR11 CDCA2 PPARGC1B KIF11 NETO2 SLFN11 TPX2 CCNB1 ANLN NCAPH GLDN CEP55 CDCA3 CDC20 KIF23 HJURP ALDH9A1 TRIP13 TTK MKI67 KIF20A SLC43A3 SCD TYMS CXCL8 PER3 ARL4C G0S2 AKR1C3 MSC SPON1 TGFBR3 AUH MYC ZFP36L1 CHTF18 ABCC2 PIK3IP1 FAM20A HMGA1 VPS9D1-AS1 FOXM1 COL14A1 TRIM16 EPHB4 SORCS2 ABI3BP PRC1 BCL3 SBNO2 COLEC12 CENPN SAA1 ARHGAP11A OAS3 CENPA GNG2 RAD54L TCF19 NLRC5 CKAP2L IQGAP3 PARPBP FAM83D SKA3 NCAPD2 DBF4 OIP5 ECT2 TACC3 NUSAP1 CKAP2 MCM5 PBK RACGAP1 KIF20B MELK DEPDC1 CCNF NCAPG2 NDC80 CENPE CCL13 EBF2 LRP8 CYP7B1 SLC7A8 C3 XAF1 CXCL3 CH25H APOL6 C1R CHAF1A KIF18A BRINP1 TIMELESS IFIH1 TNFAIP6 CCDC18 CACNA1G PLEKHA4 SOCS3 NAMPT SLC39A14 PARP14 FOSL1 HAS2 GFPT2 SNAI2 ACKR4 PCOLCE2 TRIL EPHB6 SLC6A15 FTH1 PSME2 ZFP36 IRF1 HMGCS1 ICAM1 DTX3L NFKBIA KLHL5 PSMB9 TJP2 SEMA3C DRAM1 PLIN2 ADAMTS15 ACAT2 NR1D2 IFI44L DRAP1 PTGR1 FAM107A PHLDA1 NRP1 KIF26B S100A10 COL6A3 PDZRN3 POU2F2 GLI3 ZC3H12A RGMA TBX3 IL16 AOX1 CSF1 VAMP1 B3GNT5 TNFAIP3 ADAMTS3 S1PR3 PLA2G4C S100A3 GIMAP2 BHLHE40 MAFF NFKBIZ ALAS1 PTTG1 MSH2 AMD1 STEAP1 LAMB1 SNRPA PFKM CDC25B RSPO3 TNFRSF19 APOBEC3C COL7A1 FOXO4 SRXN1 AKR1B10 INSIG1 MAP2 MCC IL1R1 PIGW TAP2 FEN1 MAP3K8 IRAK2 TFRC PDGFRL ALDH3A1 CYP1B1 PCSK9 SLC43A2 IL32 MCM4 MCM7 DDX60 DNA2 TFPI2 DIS3L FUT8 RELB ETV7 CX3CL1 APOL3 NCEH1 BTN3A1 C1S SOD2 CBR3 BTN3A2 OPTN RAB8B PF4V1 RAP2B FJX1 DNM1 CD70 PAMR1 ENPP2 ADAM12 CSMD2 SAA2 RNF144A ITGA9 PCDHGC5 IFNGR1 MTSS1 BDKRB2 ORC2 UBE2H TNIP1 HLX GDF5 PPARGC1A TNFRSF1B CA12 F2RL2 NFKB2 BDH1 TRAF2 IRAK3 ALDH3A2 RAB3IL1 SLC12A8 TSPAN5 FLCN SLC39A8 SPATS2 CAMKK1 UNKL COL27A1 LSS CHI3L2 GGA2 SLC38A5 ABLIM3 TRAF3IP2 SRPX2 LRP1B GAS7 CMBL STEAP2 COL11A2 ENOX1 SLC2A12 DCLK1 SMC4 ABCA9 CIP2A PCLAF SLC9A9 LTBP1 KCNK2 SLCO3A1 GCLM AKR1C2 ABCA6 ADH1B AKR1C1 UGCG PPIF GEMIN4 POC1A CENPO TEF RAG1 DOCK2 SLC11A2 ASPH ADGRG6 WTAP TIAM2 BAHCC1 NRCAM DHCR7 STXBP6 TRIM47 REV3L ZNF395 ZNF608 GPSM2 FAM198B CD109 CCBE1 COL22A1 WDR62 SVIL PLPP3 RGMB RIPOR3 ARL4A SGO2 PIMREG SLC41A2 C1RL ELOVL2 LUC7L2 EDA2R STRIP2 P2RX7 MAN1A1 ATP8A1 CCP110 C18ORF54 GALNT15 OSR1 WFDC21P LDLRAD3 FAXDC2 KIF24 EBF1 SLC36A4 NBPF19 C1GALT1 MTBP SLC44A1 RFXAP GPRC5B FBXL14 SPATA18 CDC42EP4 MICALL2 CNTNAP1 THSD4 AK5 RCBTB1 LPAR1 LUCAT1 BEND6 SDK1 CBLN3 ST8SIA1 ARHGAP28 KMT5C CLDN11 SCMH1 RGS20 MST1P2 SNED1 MOXD1 GDF6 PKNOX2 COQ8A CUTC NTM PCDHB13 SYTL4 OSER1-DT C4ORF46 ARHGAP22 EVC2 NMRAL2P ZNF423 LINC02015 MSC-AS1 APCDD1L PCBP3 LOC100129940 LOC105747689 CARD8-AS1 SLC4A11 LINC00926 SIX2 LOC100130027 LINC01094 LOC100996724 PARGP1 PTENP1 ZBTB12 LINC01397 MT1L CRYBG1 RFX8 LINC00839 ADGRL4 SNHG21 Top 500 downregulated genes for SARS-CoV-2 infection in human limbus from GSE164073 How Related: Limbus was isolated from human donor tissue and passaged in tissue culture. Cells were infected with SARS-CoV-2 for 24 hours in triplicate and the host response was compared to mock-infected samples. GEO Accession: GSE164073. GEO Title: Response to SARS-CoV-2 infection in cornea, limbus and sclera from human donors. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/GAx5ZhYyF TM4SF20 MALL SMOC1 BAIAP2L1 TMPRSS4 PVR HOOK1 ST14 NEDD9 KCNQ1 MPZL3 SPTBN2 TMPRSS11D TMEM173 PLS3 EPB41L4A FERMT2 TMPRSS13 SLC44A2 LRRC1 OVOL1 PLEKHA7 VAMP8 CD55 FZD5 STXBP2 ALDH1A3 RASEF CEACAM6 TMC5 SPRR3 MUC21 SDC1 KRT18 KRT7 PIGR NEBL DDAH1 CFTR MSMB KLF5 ERBB3 KRT17 TTC9 SLC40A1 FGFR2 AQP5 GCNT3 RAI14 UPK1B MUC15 SYTL2 DUOX2 HOPX CXCL17 RAB25 ELF3 LMO7 MYO5B PAWR SCEL GALNT3 DSG2 SERPINB2 C1ORF116 H19 STEAP4 BCAS1 SLC25A4 MAP6 KRT19 SYTL5 KRT15 MUC16 EFHD1 TRIM29 SLPI NDRG2 GPRC5A CEACAM5 SORBS2 RIMS1 ESRP1 TACSTD2 PSCA LCN2 AGR2 ANK3 KRT8 TACC2 EHF MYO5C GRAMD2B DHRS9 TC2N TTC22 VTCN1 GABRP SPRR1B MAL2 ATP10A MPZL2 KCNK6 ITGB2 TMC6 AQP3 MYADM ADGRE5 RHOB SYNGR2 MACC1 WFDC1 ITGA1 ROGDI CLDN7 PADI2 MERTK SORT1 ALDH4A1 ICAM5 B4GALNT3 ESRP2 ITGB8 TPM2 NOG UPK3B CRYBG2 CAMK2N1 COLGALT2 TJP3 NUAK1 LLGL2 ADIRF TUFT1 ZNF185 GADD45B CDH1 ACTB BDNF SPINT2 SPINT1 EPN3 CGN CLDN4 AP1M2 WNT7B TMC4 PROSER2 SCNN1A TMEM184A JUP PTK6 ARRDC1 GRHL2 SERINC2 ALS2CL PPP1R13L PROM2 KRT80 MYH14 HACD2 BICDL2 TPD52L1 EVPL B3GNT3 EPS8L1 FZD1 WNT4 FGF7 SFRP1 FGF1 DACT1 DIXDC1 MAP2K3 DKK2 KRT13 OTX1 SLC8A1 PAX6 PTPRU FZD7 NBEAL2 DDR1 PDLIM5 B3GALT5 CTSS TMEM45B S100A9 CHL1 PRSS22 CYP26B1 IL1RN NTRK2 ALDH1B1 HAS3 RAMP1 TINAGL1 DIO2 XDH PTGES F3 C5AR1 ITGA8 NEGR1 KAZALD1 RIMKLB INMT ACTC1 TSC22D1 AARD CNN2 FOS ACTG1 BMP6 SGK1 CRYAB DUSP1 MYL12A ID3 SMAD6 CDC42EP1 CLIC3 CLIC5 PXDC1 MYH1 SLC34A2 CTGF LIMCH1 ALDH1A1 TAGLN PPP1R14A LTBP3 FHL1 RGCC NPR3 LIMS2 RAPGEF3 TUBB2A EHD1 DSTN LBH C1ORF198 RFTN1 FSCN1 PICALM GEM ATOH8 PTGER3 RBM24 SLC38A4 LYPD2 TBC1D10A FILIP1L TP53I11 MUC1 BAMBI PFKFB3 TSPAN31 CFL2 CKB UBE2E2 C19ORF33 SDC2 SGMS1 SLC44A3 GJA1 TUBB6 HSPA1A AMIGO2 HSPA2 GRHL3 SLCO2A1 GRB7 PDE4B EXTL1 CNN1 ANKRD1 C1ORF226 ID1 PGM1 C15ORF48 CSRP1 TMEM200A KRTAP1-5 SMAD9 B3GNT8 MSLN ATP10B MYH2 S100A8 MUC20 NALCN CDC42BPG SLC1A4 ACTN4 CTSV CAPN14 CYP4F11 CEACAM7 RARRES3 LIPH CORO2A CAPN12 CEACAM1 OXTR DUSP4 BLNK SERPINA1 ACTN1 RAB31 MYL9 CSF2RB MEX3B ACTA2 SMOC2 LMOD1 EGLN3 LMCD1 PDLIM3 SLC25A32 GREM2 SEMA7A NR4A1 TMEM130 MCAM IVL CALD1 ANO1 ACTG2 CARD11 KRT24 SPRY4 SLC6A17 JPH2 SLC6A14 SCUBE3 CPNE4 CORIN DOT1L BACE1 MRAS TIMP3 SPRYD3 IFITM10 EEF1A2 TNFAIP1 FBLIM1 WTIP TPM1 RIN2 NFYB NT5C2 SUSD2 NPAS1 DMPK OBSL1 MEGF6 ANKH MDGA1 HAPLN3 GPRC5C C16ORF58 HDAC5 KCTD15 NEXN DAPP1 HSPB6 KLK10 INPP5K CTPS1 DTX4 VSIG2 SPHK1 PCDH1 FAM3D PRSS27 PRSS8 GLS SPCS3 ELN FUT3 GGT6 TGFA STK38L MUC7 MAGI1 ID4 SLC44A4 ARHGEF37 KRT78 SHROOM3 FXYD3 VSIR COL10A1 NXPH3 ZFAND5 ADAMTSL4 RABGAP1 ATG9B LEP HSD17B6 SOX4 RASSF2 PODN HSPB7 DOCK8 KRT23 ADGRF1 F11R GPC4 NECTIN4 PSG4 RHOBTB1 RUSC2 ZSWIM4 FSTL3 RAB11FIP1 FAM83A GNA15 NCCRP1 ENDOD1 MBOAT1 DTD2 PPP1R3C PCDH7 TES RASGRP2 SAMD11 KRT7-AS DHRS3 SPNS2 PPFIBP2 MYOM1 SLC20A2 PADI1 PRRG4 SSPN PRAG1 FCHSD2 CCDC88C GRHL1 ACAN PPME1 PDLIM7 MFAP3L CXADR ARHGEF17 COL8A2 SHISA4 MRVI1 ITIH5 ADAMTS7 ADARB1 LOC100506098 SORBS1 RASSF7 INAFM2 PTGIS PPP1R12B LRRFIP2 FMN2 PALM SYT15 CDS1 RAVER2 OSBPL9 CTTNBP2NL ATP6V1C2 RNF141 RSPO2 MFSD4A JAM3 WIPF3 SCARF2 FER1L6 GMNC TALAM1 MFAP5 FAM180A MBNL1-AS1 KIAA0355 JAM2 LINC02593 INAVA ACTA2-AS1 LOC104968399 PLCE1-AS1 KIAA1324L OTULINL LOC145694 LINC01013 LINC01111 SHISAL1 CLVS1 VGLL4 PAPPA-AS1 LOC102467080 CMAHP SFTA1P PRELP Top 500 upregulated genes for SARS-CoV-2 infection in human sclera from GSE164073 Sclera was isolated from human donor tissue and passaged in tissue culture. Cells were infected with SARS-CoV-2 for 24 hours in triplicate and the host response was compared to mock-infected samples. GEO Accession: GSE164073. GEO Title: Response to SARS-CoV-2 infection in cornea, limbus and sclera from human donors. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/tQ9H9XeSA CEP350 BIRC3 IL6 DPP4 CCL2 CD34 ABCC1 ANPEP SQSTM1 VDR NMI STX3 CXCL5 MME TOR1AIP1 RUNX1 PTX3 FN1 ADAM17 B2M FBN1 AGTR1 ITGA4 CXCL2 HS2ST1 PTPN4 ZC3H12C PCMTD2 ZBTB44 AFAP1L1 LIFR GBE1 METTL7A CACNB4 ACO1 CXCL1 CXCL6 TNFSF10 SRGAP1 LMO3 ASS1 OLFML2B TRPS1 REPS2 CGNL1 NFAT5 FOPNL PPL PNRC1 TRIM2 RICTOR ITGA10 ADH1C STEAP4 PTGFR FAM214A SATB1 RND3 SSBP2 TPST1 ZBTB20 MDM2 TNFAIP2 PGD APOL1 TGFBI LRP1 TKT ABCC3 SLC6A6 ME1 SQOR CREG1 MGST1 IFI44 FKBP5 PDGFC GPNMB MAFB CES1 BCAT1 EPSTI1 PAX8-AS1 HGF CARD6 C2 LGALS3 CDKN2B DPYD IDH1 SH3PXD2B SCD GNPDA1 CXCL8 ARL4C CEP126 PTCH1 CHI3L1 CHIC1 G0S2 AKR1C3 MSC TGFBR3 EFNA5 ZFP36L1 PLCXD3 PIK3IP1 SERPINF1 FAM20A COL14A1 TRIM16 WLS MRO PYGO1 BNC2 SORCS2 CLU ABI3BP SFRP2 BCL3 TRIM8 HSD11B1 CFB APOD NLRC5 TNFSF14 LACC1 CYP7B1 SLC7A8 C3 XAF1 CXCL3 CH25H APOL6 CTSK C1R IFIT2 IFI16 BRINP1 HERC6 KIZ IFIH1 TNFAIP6 CACNA1G NAMPT GBP2 PARP9 SAMD9L GCH1 NFIL3 SLC7A11 PIM1 SERPINA3 FAP RNF213 ASAP3 SLC39A14 PARP14 HAS2 SAMHD1 F3 PPA1 GFPT2 TLR3 ACKR4 LRRC17 SLC6A15 IRF2 FTH1 KLF4 IRF1 TMEM100 HMGCS1 TXN ICAM1 DTX3L NFKBIA KLHL5 JUNB SEMA3C DRAM1 PDGFRA S100A4 DCN ADAMTS15 BTG1 SERPINE2 DPT IFI44L TAPBP DDR2 TP53INP1 PTGR1 FAM107A MYLIP SAT1 S100A10 COL6A3 NOVA1 GLI3 ZC3H12A RGMA TBX3 IL16 RAB30 SCARA5 CSF1 SRPX TRIM22 VAMP1 HMCN1 LRRK2 TNFAIP3 COL21A1 S1PR3 PLA2G4C CPXM2 CLSTN3 PLA2R1 TNFRSF14 NFKBIZ CTSO TNFRSF21 STEAP1 AKR1B1 RB1CC1 MXI1 CDC25B TAF4B ZMAT3 NEAT1 COL7A1 ZCCHC24 TBL1XR1 SRXN1 AKR1B10 C6ORF120 INSIG1 CREBRF MSMO1 HMGCR KLHL24 MAP2 MCC ROBO1 IL1R1 CD47 SLFN5 PDK4 RASD1 MAP3K8 IRAK2 PDGFRL ALDH3A1 NID1 SLC43A2 PELI2 BMPER IL32 DDX60 MAN2A1 BBS2 AHNAK2 NEB TNFSF13B SP100 HERC5 EFHC1 PIK3R1 FUT8 FNIP1 PNISR RELB BTN3A3 APOL3 BTN3A1 C1S PLSCR4 SOD2 CBR3 BTN3A2 PXK IL18R1 OPTN CFLAR RAB8B ARHGEF3 ADD3 KANSL1L ZNF546 ZNF280D CLK1 TRIM16L BACH1 DNM1 ENPP2 MMP2 DPYSL3 SCN2A RNF144A NCOA7 CXCL12 PRKG1 IFNGR1 BDKRB2 PEX2 TENT5A UBE2H OLFML1 GDF5 POSTN CA12 F2RL2 MMP14 NFKB2 SC5D CYLD IRAK3 ALDH3A2 ABHD5 GPR1 EPHA4 RAB3IL1 SLC12A8 FLCN C14ORF132 DYNC2H1 ERAP1 USP53 SLC39A8 PGPEP1 ABCB6 NR0B1 UNKL LSS FAM102A POPDC3 CYP19A1 ACSL1 CHI3L2 SSH2 NFATC4 HBP1 DST SASH1 HIPK2 WBP1L TRAF3IP2 TRIM13 FDFT1 NFE2L2 PRKCE GCLC CMBL PARD3 STEAP2 ENOX1 SLC2A12 DCLK1 CCNG2 SATB2 ABCA9 WISP1 COPS8 BCL2L11 SLC9A9 DDIT4L TMEM106B LUM PLD1 WHAMMP3 SNX13 LTBP1 KCNK2 SLCO3A1 SPTLC3 CYP51A1 HTR2A GCLM AKR1C2 ABCA6 ADH1B AKR1C1 MAP3K2 LNX1 RRM2B CCNG1 PMS2 AKNA SLC11A2 UGDH SPSB1 DTNA ASPH HECA PCNX2 LYST WTAP BAHCC1 NRCAM DHCR7 TRIM47 REV3L TENM3 PGAP1 ARHGEF6 UBN2 TLK1 ZNF608 MAN1C1 HEG1 NCR3LG1 CD109 ECM2 ZNF277 NABP1 TCEA1 ANK2 ZC3H6 JMY LGR4 PTPRK BICC1 SVIL CREBZF RAB27B ANKRD10 BAZ2B RGMB MIR193BHG HECW2 GABPB1-AS1 RIPOR3 CCDC69 VWA5A SLC41A2 PRG4 C1RL EDA2R VPS13C MAN1A1 ATP8A1 ACAP2 GALNT15 ACACB DAB2 SESTD1 WFDC21P FAXDC2 YPEL2 FOXN3 HMBOX1 SMIM14 C1GALT1 SLC44A1 GPRC5B WHAMMP1 SPIN3 SPATA18 MICALL2 ME3 CNTNAP1 WASF3 ZNF483 BEND6 RFTN2 TENM4 RUFY3 CBLN3 ST8SIA1 NXPE3 ARHGAP28 CLDN11 SNED1 MAML3 ZNF521 DNM3OS ASPN COQ8A CUTC ADAM33 ZNF577 PSMA3-AS1 LINC01239 NMRAL2P FIBIN MSC-AS1 LINC00607 APCDD1L LOC100129940 LOC105747689 CRYBG1 CARF ADGRG2 NIPBL-DT C1RL-AS1 OMD ZNF37BP MIR34AHG AMZ2P1 Top 500 downregulated genes for SARS-CoV-2 infection in human sclera from GSE164073 Sclera was isolated from human donor tissue and passaged in tissue culture. Cells were infected with SARS-CoV-2 for 24 hours in triplicate and the host response was compared to mock-infected samples. GEO Accession: GSE164073. GEO Title: Response to SARS-CoV-2 infection in cornea, limbus and sclera from human donors. BioJupies notebook: https://amp.pharm.mssm.edu/biojupies/notebook/tQ9H9XeSA MYH9 GNA11 UHRF1 FGL2 MALL BCAR1 CCND3 EZR PFKL PVR NEDD9 FBLN5 TUBB4B HSPB1 KLF6 HSP90AA1 TUBA1C ATP1B1 PDE4D MFGE8 PLAT PLS3 TGFB1 YWHAH MTCH1 HSPA8 DIAPH1 FERMT2 SLC44A2 CDK2 SIPA1L1 TLN1 CABLES1 FZD5 MYO10 KRT18 ENAH KRT7 DDAH1 MYO1B TM4SF1 SLC40A1 FGFR2 RAI14 SH3RF1 METTL7B PKP4 LMO7 CNN3 RHOBTB3 H19 SLC25A4 C12ORF75 SLC2A1 KRT19 EFHD1 GPRC5A RIMS1 ISG20 GCNT4 GRAMD2B CCND1 ATP10A ARID5A PRPS1 NACC1 THBS1 VASP FLNA PTK2B EMILIN2 MYADM SLC16A3 EHBP1L1 ADGRE5 ARHGDIA RHOB ZYX MYBL2 TOP2A ZWINT CDCA8 CCNA2 CLSPN TK1 LMNB1 GTSE1 UBE2C AURKB SHCBP1 MYO1E CDCA5 IGFBP2 SPAG5 ITGA7 MCM2 WFDC1 KIF2C CDC25A AURKA BUB1 RRM2 CDK1 PAQR4 CDC6 BIRC5 KIFC1 MCM10 TPX2 CCNB1 ANLN DEPP1 CEP55 CDCA3 CDC20 KIF23 PKMYT1 SKA1 TRIP13 TTK ARHGAP23 MKI67 LDHA TPI1 DTL NCAPG TYMS CRIP2 IL7R TPM2 NOG FGFRL1 PTGS2 A2M CAMK2N1 KLF2 ADIRF CTNNA1 GADD45B BMP4 ACTB BDNF PPP1R13L GIPC1 SLC7A5 TPD52L1 FZD1 FGF5 SLC4A2 FGF7 SFRP1 WNT2B ANKRD6 WNT5B DACT1 FZD4 MAP2K3 SLC9A3R2 SLC8A1 PRC1 PDLIM5 SELPLG FANCI ASF1B KIF22 TCF19 GINS2 CHAF1B IQGAP3 SPC24 TACC3 ERCC6L NUSAP1 MCM5 TOX RACGAP1 SPC25 DEPDC1 MAD2L1 NCAPG2 POLE CENPE SYT12 GINS1 CHAF1A CCNE2 NAV3 RAMP1 TINAGL1 TNFRSF12A ADM RASL10B ITGA8 ANGPTL2 KAZALD1 RIMKLB INMT ACTC1 AARD LASP1 CYR61 TNS1 CNN2 IGFBP4 ACTG1 CRYAB MYL12B DUSP1 TGM2 MYL12A ID3 SMAD6 CDC42EP1 CLIC5 PXDC1 CTGF CRIP1 EFEMP1 LIMCH1 ALDH1A1 MYH10 TAGLN PISD TUBB FHL1 NPR3 PLEKHG2 LIMS2 AQP1 CFL1 EHD1 LBH FSCN1 PICALM VCL ATOH8 EMX2OS RGS4 MBP PENK LYPD6 SOCS2 TENM2 SPON2 TP53I11 ADRA2A AMOTL2 DUSP5 ZNF367 BAMBI PFKFB3 SH2B3 UBE2S GYS1 PGAM1 RNASEH2A CKB SLC29A1 STIP1 MAGED1 SDC2 BCOR CORO1C MGLL SSB SLC10A3 TUBB6 HSPA2 VAV3 PDE4B RANGAP1 ANKRD1 ID1 PGM1 PRRX2 DIAPH3 ATAD2 CEMIP CSRP1 MCM6 KRTAP1-5 CHSY3 SMAD9 ITPRIP MAP3K14 FEN1 GCHFR ACTN4 MAP1S FGFR3 CDKN2C SYPL2 CRABP2 MCM4 SLC20A1 PLAGL1 FAM111B MCM7 IDH2 LMNB2 LIG1 NCAPD3 KCTD12 CRIM1 ACOT7 TCEAL3 RCAN1 GMPR CTNNAL1 OXTR CHSY1 NMU ACTN1 MYL6 MYL9 GAS1 HEYL ACTA2 LMOD1 LMCD1 ZNF469 FHL2 GREM2 SEMA7A NR4A1 RCAN2 OLFML3 TMEM130 CSPG4 MCAM SDC3 ADAM19 CRLF1 ROR1 CALD1 SPRY4 FANCA TMEM214 PYGM SEMA3B HPD SCUBE3 CORIN PGK1 SKP2 SARM1 DOT1L MRAS RECK TIMP3 PCSK2 ATP2A2 SPRYD3 ARPC5 TNFAIP1 VTN GALNT1 WTIP TPM1 NXN ATP8B1 EPHA2 SUSD2 CCNYL1 NPAS1 DMPK ANKH MDGA1 RALY HAPLN3 HDAC5 KCTD15 HSPB6 INPP5A KCTD20 SNAI1 CTPS1 ADCY6 PLXNA2 FLNC LRRC32 SPHK1 NAB2 ITGA3 GLS SPCS3 WDR1 PITX2 SRF MAGI1 EYA2 SHROOM3 VSIR NOTCH3 MYO1C DAPK1 NXPH3 EVA1A ADAMTSL4 CMKLR1 NDUFA4L2 LEPR HK2 LEP DRD2 PLA2G2A PEA15 MCM3 MET IL11RA RECQL4 HNRNPAB NUP188 LATS2 HSPB7 RHOC LOXL3 NANS FLNB GPC4 PIP5K1A PSG4 RASAL2 DLC1 FSTL3 PACSIN3 MICAL2 ANXA6 AFAP1 COL8A1 MTSS1L ENDOD1 PPP1R3C VGLL3 RASGRP2 SAMD11 WDR62 PHACTR2 CAVIN1 NTMT1 JPT1 OLFM2 MYOM1 PFKP RAI1 PRAG1 MPRIP PIMREG DBNL DOCK10 ACAN NID2 MAMLD1 PPME1 PDLIM7 RAB3B PSG5 ARHGEF17 SOX8 COL8A2 MRVI1 ADAMTS7 ADARB1 MCM8 SORBS1 INAFM2 TLE2 JPT2 FMN2 THSD4 ARSJ SYT15 ITGBL1 SH3D21 OSBPL9 MTMR10 KCNB1 NCS1 KCNK3 P3H2 RNF141 WWC2 KAZN AFF3 ARNT2 PCBP4 SCARF2 NFASC MFAP5 KIAA0355 LINC02593 OTULINL SHISAL1 SFTA1P LINC00968 DAAM2 GPR4 CASP17P ADAMTS12 KANK1 Top 500 upregulated genes for SARS-CoV-2 infection in human lung organoids from GSE148697 Lung organoids were infected with SARS-CoV-2 and compared with mock-infected cells. GEO Study Title: Identification of Lead Drug Candidates for COVID-19 based on Drug Screening Using Human Pluripotent Stem Cell-Derived Cells/Organoids. GEO Accession: GSE148697 . BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/AHhi5tcbp NKX3-1 ADAMTS1 JAK1 EEF1A1 BIRC3 CCL2 VCAM1 ANPEP STAT3 TMPRSS2 SQSTM1 UBD SPINK1 EPB41L2 DNAJC11 TNF CXCL5 DDX5 THY1 CXCL10 EPB41 ACE2 CXCL16 TPM4 IFITM1 FABP1 COL4A1 ANXA2 ACSL5 IGSF3 HLA-B CLCN6 CTNNB1 NFKB1 SERPINE1 FYCO1 FLT1 DNASE1 COPB2 PTX3 TP53 FN1 NR3C2 TRAF3 B2M FBN2 HHLA2 CXCL2 HKDC1 PPIA MUC13 SIPA1L1 NEO1 MYO10 CP CXCL1 CXCL6 SLC22A23 CEBPD DUSP16 CGNL1 ZEB2 THRB RPL41 RPS24 GPX2 ELF3 OSMR KIAA1217 CFH CCDC80 PLCB4 ZNF827 ANKRD33B RGL1 FOXQ1 SGPP2 EHF RPL7 RPS27 ANKRD52 TNFAIP2 PIEZO1 IL4R THBS1 RFX5 TGFBI TYMP B3GNT7 ITGA5 SDC4 ALDH1L2 AREG LDLR FKBP5 FADS1 ITGA1 CARD6 EIF4G1 PDIA5 CDKN2B HP KCNMA1 TYMS G0S2 PTGS2 AKAP12 IGFBP3 SLC2A6 MYC COL5A2 MANF EP400 FAM20A MTOR BCL9L WWC1 FGF11 SFRP1 GABARAPL1 ESRRB TNFRSF11B HIF1A TFE3 BCL3 CEBPB SBNO2 COLEC12 SAA1 OAS3 CFB TNFRSF9 TAP1 CCL20 CTSS MYBPHL IFIT3 C3 CXCL3 APOL6 CCR1 CTSK C1R COL3A1 FGG CLDN2 SOCS3 TREM1 NFKBIE NAMPT GBP2 PARP9 CASP4 SERPINA3 RNF213 PARP14 PCDH10 F3 PLAU CSF3 SCUBE2 ITGA8 MICALCL BTG2 FTH1 ETS1 SHANK3 ZFP36 IER3 IRF1 SGK1 TGM2 HMGCS1 ICAM1 NFKBIA KLHL5 JUNB SLC34A2 CTGF VEGFA MAT2A PLIN2 SERPINE2 HLA-DQA1 ACAT2 MYH10 C11ORF96 TAPBP FHL1 SH3PXD2A EFNB1 DNAJA1 RPL36AL UQCRHL LRG1 SAT1 KIF26B COL6A3 RRAD ZC3H12A MAB21L2 TRPC3 ISM1 FAM167A PPP1R15A CSF1 TRIM22 KCNE4 MXRA5 HMCN1 BMP5 GPR111 TNFAIP3 IL23A S1PR3 MUC1 NEURL3 LIF BHLHE40 MAFF NFKBIZ STIP1 VMP1 PRPF3 HOXB7 LAMB1 IL17C PCSK5 MORC4 SLCO2A1 NEAT1 EFNA1 SAMD4A IK HDGF HIVEP2 ZNF337 C15ORF48 RND1 ROBO1 IL1R1 ZNF211 PRRT2 STAP2 TAP2 APOA2 PNPLA3 SLFN5 TRIM14 MAP3K8 RIPK2 CTSE OLR1 IRAK2 TESC PVRIG GSDMB IL32 CFI LPGAT1 CASC3 ST3GAL1 CKAP4 PSTPIP2 CRIM1 ASH1L LAMC2 SRRM2 CD83 PLK2 RELB CHST15 NFE2L3 CLUHP3 TICAM1 CX3CL1 PATL1 SP140L C1S SOD2 MOB3C PARP8 OPTN CFLAR C8ORF4 SERPINA1 MYL6 CASP8 LTB RASGRP1 ACTA2 HERC2P2 RASSF4 CDC42EP2 IL1RAP BCAR3 XYLT1 CCAT1 PAPPA LAMP5 HHIP LOXL2 IGF2 CXCL14 KANK4 COL12A1 ITGB6 ADAM19 ADAM8 PLSCR1 ADAMTS9 SPRY4 ABCA12 NCOA7 MYO16 SLC6A14 C12ORF36 ANGPT2 IFNGR1 IFNAR2 IKBKE TANK TNIP1 MAP4K4 MRAS SPEN ROS1 PARP1 TFEB IFNGR2 NFKB2 SNW1 CYTH1 SULF1 WIPI1 AHNAK CDC37 CDC42SE1 BOC FIP1L1 LOC202181 ANKRD11 LTV1 DNAJB11 FGA MIR600HG FBXO10 PIM2 BCL6 DAPP1 CHI3L2 RBM6 MICAL3 DST ABR FDPS PPARD TRIP10 HILPDA SLC7A6 MMP7 APOB CHDH ECE1 SMARCC2 PRSS12 PDE9A MAST2 BACE2 SETD5 IFT57 MSRB3 WISP1 TNFRSF10B ATG4A PRKCG UBR4 ZNF720 ZNF641 DNAH5 MTHFD1L ZFHX4 HUWE1 SLCO3A1 SERPINA4 HGD PLA2G2A COL5A1 ACSS2 SLC2A14 SYNPO PEA15 TNC ALDH1A2 HNRNPAB TCOF1 AFP HSPA9 NFKBIB COL16A1 AHCYL2 TMEM51 PNKD NANS OSBP CELSR3 SCAF4 PIP5K1A DDX24 ABTB2 KIF21B LRRN3 SLC25A37 HIVEP1 MICAL2 KCTD11 TENM3 ANKRD50 SULF2 RAB15 IGF2BP2 SBF2 GFRA1 COL22A1 KAT6A SVIL GPATCH4 SLC26A9 TRIO CWC25 ZBTB7A PRRX1 SIPA1L2 EIF4G3 MPRIP GABBR1 TTC28 SF3B2 EDA2R ZRSR2 SVEP1 DOCK4 JAKMIP2 DNAJC12 MGAT5 LRP4 HOXD9 SLIT3 COL23A1 MGAT3 SSBP3 TMEM63A RAB3IP EIF2B2 IL8 LOC646278 KIF2A CNTNAP1 PIEZO2 LOC102723726 DIEXF IGF2BP1 DACT3 SCG2 TBX4 ALPK2 ZNF589 BEND3 MIR3916 PHF8 ERVK13-1 ADAMTSL1 ARNT2 IGFN1 IGFN1 LOC102724608 LOC101928706 AC007966.1 C1R-2 LOC101928451 ZNF547 SNORD84 LINC00908 LOC101927940 LOC101928814 LOC101929792 LOC102723546 LRRC55 KNOP1 HOTTIP RP11-3P17.4 HOXD11 CCDC40 LOC102723808 LARP6 LRRTM4 LOC102724554 WWC3 LOC100506379 ASB4 HOXD10 Top 500 downregulated genes for SARS-CoV-2 infection in human lung organoids from GSE148697 Lung organoids were infected with SARS-CoV-2 and compared with mock-infected cells. GEO Study Title: Identification of Lead Drug Candidates for COVID-19 based on Drug Screening Using Human Pluripotent Stem Cell-Derived Cells/Organoids. GEO Accession: GSE148697 . BioJupies Notebook: https://amp.pharm.mssm.edu/biojupies/notebook/AHhi5tcbp NDFIP2 AMACR RAB2A FCGRT RB1 ATP13A3 TRIM59 LOX MPP5 ATP6V1A MIB1 TMEM65 ATP6AP2 SEPP1 RBX1 PLEKHF2 HOOK1 UBE2D1 XIAP NPTX1 ZYG11B RAB18 PDZD9 ARL6IP6 SLC30A7 HS2ST1 TMED5 ARF6 NTS RAB10 GGH LYRM5 C1D SCRN3 CHPT1 LRRC40 LYPLA1 SPTLC1 NUDT12 TMEM30A METTL7A RWDD3 NDUFB6 FBXL3 NAGLU TFF3 PERP NEBL DDAH1 HES1 GULP1 PARD6B YAP1 HOPX RHOBTB3 FREM2 PAWR TRIM2 MZT2A RICTOR FAM214A CKS2 MBNL2 TPD52 EMP2 MAL2 MPZL2 AQP3 ENPP4 SRD5A1 CREG1 DEPDC1B SDHD CDK1 BCAT1 RMI1 PRDX3 C5ORF30 IKZF2 ENPP5 PLEKHA1 CHIC1 AZIN1 HINT3 TGFBR1 PGAP2 CYCS IMPA1 MROH6 CLDN3 PYGO1 FZD3 BMP3 SOX11 SHISA2 DCK KRT13 GPM6A UBE2Q2 CENPK SGOL2 ECT2 DEPDC1 MAD2L1 KIAA0101 CHRDL1 PCDH20 NT5C3A NINJ2 KCNIP4 DDC CLIC4 SPTSSA TSPAN13 PTGES3 LAMTOR3 PPP1CB UBL3 SH3BGRL NR1D2 PPP1R14A SLC12A2 EID1 HCFC1R1 DYNLT3 SMIM15 PCNP LRRC58 NDUFA5 NDUFC1 RTKN2 DSTN CAPZA2 NAB1 RBM7 VPS26A VBP1 SEC61G CD164 DEK SPOCK3 TMEM14B C21ORF91 FEM1B SOWAHC MAGT1 SELT CRYZ CFL2 WRB TMX1 TEX30 SRP9 GPR160 MRPL42 GOLT1B TMEM14A ANP32E RCN2 HRSP12 COMMD8 WDR83OS GNAI1 SYPL1 TMPO NAA50 AP3S1 USP1 PVRL3 FGF13 SNHG6 ERH SNX10 PPP1CC HSPE1 SNRPE FAM122B C9ORF41 IER3IP1 NEK7 AGPAT5 GNA13 ERO1LB SLC25A46 HSD17B11 SYT13 CUL4B TMEM47 ARL6IP1 TMEM170B MNS1 TBL1XR1 C7ORF60 PURB SCARNA17 TXNDC16 GNB4 UHMK1 PCSK1N PPM1K GCA DCP2 NOXA1 SFTA3 FGFR3 LBR TMEM126B MAN2A1 ALG10B C10ORF32 TMEM56 SMAD5 MIS18A TIA1 BET1 STARD4 ZBTB6 SCOC ZRANB2 KCTD12 KIAA1033 APPL1 SPAST SIKE1 SCAMP1 LINC01184 SLC25A36 ARL5B FMR1 ZBTB33 RAB8B NMU SERP1 SRSF11 B3GNT1 RBBP8NL NAPEPLD SNHG7 GRPEL2 CGA SIAH1 MTSS1 SKP2 AASDHPPT PSMG2 PPA2 COX11 UBE2B C3ORF14 KIT FOXJ1 EGLN1 RNF11 STX7 TMEM167A TSNAX GNPNAT1 ZDHHC20 KPNA5 ACTR6 CRLS1 PI4K2B RAP2C RFK YIPF4 CMAS CMPK1 CGGBP1 C4ORF3 C5ORF15 KRT10 ARL5A COMMD10 PAQR3 DNAJB14 ETAA1 ZBTB10 TMEM123 GTPBP10 MEGF6 PPP1R3B MIER1 NEXN C19ORF48 SPRED1 WASL GLS SPCS3 CPNE3 GMFB ACVR2A CPM SERPINB13 CRISPLD1 LIN7C SLC2A12 SUZ12 YAF2 TRIQK FOXA2 CISD2 RAB33B TMEM106B SESN3 NOD1 FGD4 ZDHHC17 ELMOD2 TDRP PCGF6 SLC18A2 RFX3 LMO4 SGPP1 ATF2 RRM2B CCNG1 ZCCHC10 RWDD1 CD2AP CCNC IREB2 OXR1 NUDT21 BCL7C ANKHD1 SKIL TSPAN12 MIER3 TMEM135 FPGT DPY19L4 PGAP1 LANCL1 PTAR1 DCUN1D1 CASD1 PHIP PGRMC2 CCDC126 AEBP2 GXYLT1 FAM171B RSL24D1 HSPA13 IGFBPL1 LIMS1 PM20D2 C3ORF58 SOCS5 CREBZF SNX18 TMTC3 CHML RAB27B ARPP19 NAA30 LCOR FOXN2 LSM5 ZXDB TMED7 KLHL28 REST DTWD2 SCAI FAM199X PRRG4 SNORD3A PPP1R2 MZT1 STYX VMA21 TMEM41B ETNK1 FGFR1OP2 SOCS4 FAM126B DR1 IKZF5 ZNF92 ZNF770 LYSMD3 IRF2BP2 KIAA1586 PTPRN2 TNPO1 ABHD17B RAB38 PCMTD1 RNF138 CUL5 MAN1A1 CNIH1 G2E3 C18ORF54 CXADR PPIP5K2 BROX MDFIC TTC33 IL17RE C9ORF40 TSPAN2 TRUB1 MFSD10 GTF2A1 ENOPH1 SLC35A3 FAM46C EIF1AX ANKRD46 NUDT4 SLMO2 ZNRF2 RNF217 CASC4 EXOC5 IPMK SUSD4 RPRD1A MAP9 CRNDE FAR1 UBE2W FCHO2 C12ORF23 MOB1B DENND1B TWSG1 ZDHHC21 C6ORF211 ZBTB41 BLOC1S6 DCUN1D4 RAP2A SPOPL C5ORF24 OSBPL8 LOC100507217 TMEM64 AP1S2 DESI2 SREK1IP1 KIAA1430 ADO MTMR6 ELFN2 BAG4 FBXL17 TM2D1 KCNT2 LPPR1 NPHP3-ACAD11 CPSF6 RNGTT WDR91 TBX1 KLHL7 CXXC4 NNAT FAM200B FSD1L PRSS35 ASB3 APITD1 ARL6 CASC9 SNORD81 SBF2-AS1 PCDHGA8 LOC100293704 MIR3685 ZNF678 KISS1R MST4 REP15 RPA3-AS1 C14ORF39 SNORD5 HSDL1 ZC2HC1A C16ORF89 KAL1 SNORD47 TRNT CEBPZ-AS1 USP3-AS1 C22ORF29 KLHDC1 AC009948.5 C5ORF38 IRX2 GPR83 KLRAP1 LRP4-AS1 PTPLA ZNF681 C2ORF54 LOC100506985 Top 209 positive hits from SARS-CoV-2 CRISPR screen from Wang et al. A genome-wide CRISPR screen in human Huh-7.5.1 cells looking at resistance to SARS-CoV-2 was performed, and the top 1% of genes were taken from Supplemental table, Table S1, sheet "SARS-CoV-2 CRISPR screen". Wang et al. (2021) Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses. Cell, 184(1), P106-119 (1/07/2021) GOT1 EGR1 MAP1LC3A ACTRT2 SCAP MPP5 RHOA ACE2 TLR4 SLC16A8 GUCA2B FURIN CTNNB1 ING4 STAT1 RAB10 RHBDD3 EXT1 CRYM CRNN NDST1 LDLR TDRD9 CENPW RNASE3 KY B4GALT7 SLC2A5 MMP11 MED23 MCCC2 MSX1 RYK TCF7L2 MAFK HELZ2 C1ORF112 COTL1 GPR141 FAP SRSF4 AARD SPTSSA RAC1 SMAD6 PLIN2 GDI2 C10ORF10 RPL18A DYNC1LI2 PIK3R6 ACTRT3 FAM187B GRM7 PPFIA3 IER5 MAFF UBE2A SEP15 PRPF3 PVRL3 ACBD5 PRR15 KRBA2 KISS1 EXTL3 NRARP DYNC1LI1 INPP1 FAM185A CYS1 TAS2R41 PPP1R9A MLF2 TM6SF1 CHST15 CSTB RAB8B PPP2R5C GALNT9 CSAG1 GNA12 DHX36 C17ORF62 AQP9 ARF5 UGP2 TOM1 EXOC2 ARAF PDE6A ABHD12 STK25 THAP7 HIRA MTA3 PRAME PEMT PLN RNF216 RREB1 RAG2 CHD6 CUL4A DDIT4L VAC14 TMEM106B DHODH ZNF543 ZNF227 SERPINA7 FLVCR1 BAAT OR52H1 SLCO1C1 PECAM1 UGDH KDM5C SFXN2 SAMD1 ZNF395 TMEM131 HOXB9 ARPP19 VPS13A DIRAS2 COA6 GABBR1 MBTPS1 PRG4 EXOC8 PIBF1 MBTPS2 TULP2 PCDH19 KCNK1 ATP13A5 PIGM ZNF584 SLC35B2 PDS5A STX1A B3GALT6 AP5S1 CNOT6L PLA2G12A EXT2 WNK4 TECRL MYOCD CNOT11 TMEM163 EXOC6 SMEK2 FER SLC35B4 CNOT1 SYCE1L ZNF777 TCEA3 TARBP1 C11ORF87 B3GAT3 XKR3 ZNF823 TTC30B KIAA1328 ZNF300 NMNAT2 PDXDC1 HSA-MIR-542 HSA-MIR-4786 HSA-MIR-4483 KIF4B CDH20 HSA-MIR-3945 HSA-MIR-1468 HSA-MIR-20B HSA-MIR-5196 HSA-MIR-6807 MAGEC3 SEZ6 HSA-MIR-3135B PAAF1 MORN3 HSA-MIR-149 HSA-LET-7A-1 HSA-MIR-3173 KCNK18 HSA-MIR-2054 C13ORF35 POLK NEK11 ZFR2 ANGPTL1 C10ORF35 LCE1C C7ORF63 HSA-MIR-3154 HSA-MIR-1202 HSA-MIR-2392 HSA-MIR-193B KRTAP10-9 HSA-MIR-3127 DDX26B HSA-MIR-3656 HSA-MIR-30D EPHA6 HSA-MIR-4449 500 genes down-regulated by SARS-CoV-2 in mouse Liver cells at 3 dpi from GSE162113 GFP vs SARS-CoV-2 Mouse Liver Day3 GSE162113 down AP2A2 CEP350 SYVN1 SUMO3 HSPA5 SLC17A4 HYOU1 APC MDN1 SPOP ERGIC1 SLC45A3 KPNB1 MOGS GCC1 UBQLN4 YWHAG NDRG1 TUBB4B ZBTB7B BAG3 SIGMAR1 HSP90AA1 MRPS27 NCK1 ENPEP UBQLN1 GGCX TUBA1C TUBA4A TARS USP48 SLC16A6 HSPA8 AGPAT2 DIAPH1 GSK3B UBFD1 EDEM1 RCOR1 GLO1 USP34 WDR89 KLF12 4932438A13RIK ATF5 NCOA5 MIF4GD MYO1B SLC15A2 DUSP16 RAI14 NFAT5 BDP1 MAP7 NEDD4L TAB2 KHSRP PTPA DNAJB2 CAD TYMP PDIA4 TRIM65 SMARCD1 CLUH TMED9 ACLY NET1 PNP SLC16A1 PSEN2 SEC23B PDGFC ITSN1 GLDC LIPA RAPH1 LRFN3 ZFPM1 CRY1 AKAP12 TJP3 MARS MANF ACTB CNOT3 JMJD6 NECTIN1 CELSR1 PROSER2 SCNN1A WWC1 TCF7L1 DDHD1 HNRNPH1 CDK2AP2 FPGS PREB ATAT1 ZCWPW1 GRID1 TECPR2 KIF13B TNK2 CREBBP TBL1X PLPPR2 CCNF KYNU SUCNR1 NFIL3 ARNTL ATP2B2 DDC TFG CLIC4 THRA HMGCS1 FGD5 SMAGP PXDC1 GPAM LUC7L3 BTG1 PABPN1 MBNL1 TSC22D3 SH3PXD2A CHORDC1 HSPH1 CALR CCNL1 TUBB2A DNAJB1 VCL TMEM147 RBM8A DDIT3 SPON2 VASN GGNBP1 ANP32A MAGT1 SLC29A1 STIP1 SLC25A15 SYNCRIP ETHE1 LEO1 SPSB3 MRPL18 DNAJB4 USPL1 FKBP4 CKAP5 COL7A1 INSIG1 HACL1 MCU BLCAP MCC MVD ODF3B TRA2B ASB13 ATF6B CREM PDK4 PIKFYVE MRAP IARS GPRASP1 AHSA2 FAM13B FAM149A PNKP SMC3 NEB TFPI2 PSTPIP2 GFPT1 RFX7 FAM210B COPG1 GLUD1 IRS1 U2AF1 AMPD2 S1PR1 BANP ZKSCAN3 GAS1 CBS CLK1 CHKA SLC17A3 PIGA SEC14L2 ADRA1B AMDHD1 HSPA1B ORMDL3 AASDHPPT CSTF3 SCO2 CLPX AGO2 DNM1L CREB1 DPP9 BACE1 SC5D ATP2A2 SEC22B IL11RA1 STX18 UBA6 ABCB11 HAPLN4 CITED2 CAPRIN1 FAM193B DNAJB14 PHC3 EML4 MED24 AHCTF1 ZCCHC7 TXLNG P4HA1 TMCC1 ADCK5 PPP1R3B TTLL12 REPIN1 PPDPF TAF1 PCDH12 DTX4 SLC25A44 DOCK6 TXNDC11 GMPPA HEXIM1 SGPL1 KPNA4 GRK5 SLC5A3 INSIG2 G6PC GAS7 NPAS2 AVPR1A STK38L MEGF9 TMIE JMJD1C PDE9A TRA2A PIK3C2A MGAT2 ZBTB21 TARDBP RAET1E MREG LRRC59 AQP8 SPHK2 UBR4 RAET1D CTH ABCA2 ZFHX4 UBXN4 TRIP11 AP1G1 UBXN7 GBF1 CYP2U1 PPM1B LEAP2 ACSS2 SLC10A5 MAP3K2 CARMIL1 MTFP1 ATF2 NFATC3 SIAH2 TXNRD2 TMED3 HSD3B7 SELENOI CS PNKD OSBP GMEB2 SRPRB FNDC3A RBM14 PMVK PLEKHB1 EBP MICAL2 LGALSL SHB FNDC4 PXMP4 PGRMC2 CEP44 SRGAP3 HSPA13 MYRF MKL2 ZBTB40 DSTYK MED13 SZT2 ADGRA3 WAPL ZSCAN29 MACROD1 MAGIX DHRS3 GALE KMT2E PDE8A RFXANK RBM10 SOS1 PALLD BRWD1 HNRNPA3 CAPN15 IRGQ PAOX ARID4B ARL4A CPEB4 KMT2D DERL2 TMEM41B PBLD2 CYP2B9 CAR8 7-SEP AOX3 AMT PRPF4B USP37 B3GALNT2 INO80D IRF2BP2 CCDC127 CAMK2B PIGN DAB2 ALG2 PIP4K2B NKTR HINFP FAM213B EXOG XKR6 COMMD7 YPEL2 CLK3 CLOCK NAT10 XPO7 STX5A ZFP110 NELFA ZFP385A AFF1 SLC39A9 SSR1 OSBPL8 DUS1L GPR137 DESI2 EML3 RNF144B CEP97 CRYBG3 MTMR4 PRKCI GPD2 SLC18B1 GALT ZFP982 LUC7L B3GAT3 AGO3 SRCIN1 BCO2 FUT11 NKIRAS1 CCDC159 TTLL3 NECAB1 ELOVL3 SNED1 SLC30A10 FAM210A ZFYVE16 ADAL CDK20 STRA6L RMDN2 GM35339 RTP3 1810017P11RIK GM12940 ALG12 INSC SLC39A2 SLC22A28 A330023F24RIK 1810017P11RIK GM12940 ALG12 INSC SLC39A2 SLC22A28 A330023F24RIK GM7463 BC024978 GM43690 AI480526 INTS2 AC162181.1 ZFP638 ZFP658 HNF1AOS1 GM43597 ZFP652 9930021J03RIK TMEM170 TMEM263 EDRF1 2900097C17RIK CAR14 ZFP236 ZFP592 GM43681 ZFP780B RABGEF1 ANKS3 RD3 ZFP329 BC029214 3110062M04RIK AC153899.1 GM2061 ZFP9 CMAH ZFP950 WRAP73 ZFP54 GM16314 11-SEP 1700066M21RIK 1500017E21RIK 0610030E20RIK 1110002J07RIK 1600002H07RIK 9030616G12RIK 1110020A21RIK CATSPER2 GM16731 5033403H07RIK 4732465J04RIK 4930556M19RIK RIC8B INTS10 GM37729 NAPB MFSD4B3 CYP2C53-PS GM20257 SIMC1 SPCS2-PS AC160029.1 ACNAT1 ACAT3 CNNM4 GM45301 ZFP397 C330006A16RIK AC152061.1 ZFP369 GM17530 COQ8A GM15832 ZFP260 CAMK1D MIS12 ATP2A1 ZFP451 MAPK15 GM15401 CYP2J9 SPG20 ZFP933 4921513D11RIK 500 genes down-regulated by SARS-CoV-2 in mouse Lung cells at 3 dpi from GSE162113 GFP vs SARS-CoV-2 Mouse Lung Day3 GSE162113 down TIMM10B TARS2 SYVN1 HSP90AB1 HSPA5 HYOU1 MDN1 SLC45A3 MOGS UBQLN4 XPNPEP2 BAG3 HSP90AA1 PLOD2 RBM28 USP11 FOXA1 UNC5CL TLN2 EGFR HSPA8 UBFD1 PLEC PDE4DIP ATAD3A 1810019D21RIK NCOA5 SLC15A2 ITGA10 ANKRD33B INPP4B MYO5C ATG16L2 THBS1 DNAJB2 CAD TYMP TRIM65 MYO1E IGHG1 LDLR GLDC PRRT4 AMPH CD163L1 CCR3 KY TRDC TSPOAP1 SLC1A7 MSC BMP7 CDKN1A TUFT1 SERPINH1 CILP2 MAPT SNPH AR JMJD6 WHRN PTK6 JAG2 MST1R NKD2 MAPK11 DVL1 ATAT1 SLC24A3 TRIM8 QPRT ITGB1BP2 CDH26 NTRK2 CACNA1G NFIL3 SLC39A14 ARNTL SCN3A SCN7A TOX2 CYR61 MYL2 DUSP1 COX17 HMGCS1 SH2B1 MAT2A PABPN1 SNRNP48 SH3PXD2A CHST1 CHORDC1 BMS1 HSPH1 DNAJA1 DNAJB1 UBE2V1 HPS4 CNTN1 ZDHHC18 NOVA1 DUSP8 ADAMTS17 TBX3 NR4A3 ASXL3 SYNGAP1 SERPINA10 KBTBD8 NACAD SPON2 SAMD15 TG CCL28 FLRT3 PPRC1 MND1 WDR12 STIP1 NOP58 PUS7 ST13 LEO1 HSPA1A CHTF8 HSPA2 MORC4 CCDC117 HSPA4L USP10 MUM1L1 HSPD1 KLF7 DQX1 MNS1 HSD17B7 HMGCR BLCAP TTF1 DPH2 MCC IL1R1 PCYOX1L DNAAF3 STXBP1 ADPRHL1 ACAP1 RASL11A PRKD2 MAP1S ANKRD13B LMAN2L CABP1 IARS GPRASP1 AHSA2 ADAM1A ADAT1 TAF1A NOL9 SLC47A1 TTC3 POGK ARMC2 GFPT1 HOMER1 JADE2 IL18R1 TRAF5 BANP ZKSCAN3 MIR17HG RBM12 SNHG17 FHL2 CHKA PIGA COL12A1 ADAM12 ADAM8 HRC FCHSD1 PCDHGC5 ASPG SV2C HS3ST3B1 HSPA1B TNFRSF25 IDI1 CAMSAP1 RIN3 RET DPP9 RAB4B CARS2 ARMC6 P4HA1 DHX29 AACS IGSF9B LSS SMPD3 TELO2 BCL6 CACNA1A FOXK2 PRDM2 PCDH12 RBM6 DTX4 URB1 FLNC TXNDC11 PPP1R16B PCDH1 LRIG1 IL23R APEX2 TNNI3K SLC7A6 PPARA SLC5A3 SREBF2 ZBED5 NPAS2 KCNJ5 AVPR1A LMTK2 PLXNA3 CTTNBP2 SRPK1 DLEC1 BHLHA15 DPY19L3 DAPK1 PROX1 CPT1B NPAS4 NCAM1 COL5A1 SFPQ MUS81 SENP8 NFYA FUBP1 TNC CREB3L1 IRS3 HDAC10 RGS6 POLR3E REXO4 CCDC137 IPO4 GRWD1 WDR4 CCDC134 PLA2G4B AHCYL2 BCKDHB PEG10 NEURL4 ARID3B USP31 BICD2 TTPAL RBM14 DHCR7 SAMD1 MMAB PCYT2 TMEM201 IZUMO4 PWP2 MFSD2A UBA5 RBM20 PPP1R3C RASGRP2 ANK2 ZDBF2 CLMP FBXL19 INTS1 TBC1D4 ZBTB40 RASA2 GRAMD1A STK36 NOCT SUGP2 POLR3D SMYD5 ZSCAN20 DIRAS2 PALLD AHDC1 GRIP2 TTLL4 SYNPO2 PRG4 AMY1 SCD1 RBM12B2 VAV2 CEP95 USP37 IRF2BP2 HSPA12A CAP2 CLASRP CAMK2B RRNAD1 USP35 MED20 CCNJL COL5A3 TUBG2 FASTKD1 FAM222B PKNOX1 METTL1 FKTN POLR1B CES2G TRP53BP1 DDX51 EFNB3 MYOCD HHATL COLQ PPP1R26 PTPN23 SNAPC4 NEK8 MYLK4 MTMR4 SIX5 IKZF4 CNTNAP1 OPCML PIEZO2 TTC21A ACRBP AMIGO1 TMEM181B-PS ZFP276 ZFP142 AW551984 SH3RF3 PRMT7 LRRC71 TRMT61A CFAP74 WDR66 PCDHGA12 CTRL LY6K MYLK3 DAW1 HEATR1 INTS3 CDH24 TTLL3 TMC7 S100A7A CCDC136 GPRASP2 RAB6B F730311O21RIK ZFP420 6330403L08RIK CASKIN1 DNAH10 GM45605 DNASE1L2 GM10069 5830417I10RIK DDX55 FAM124B FAM212B GM35339 RBM12B1 SLC2A4RG-PS GM9899 ZFP319 MIGA2 KCNG2 RTP3 C78859 ZFP692 GM15344 GM12940 ZFP692 GM15344 GM12940 INTS2 ZFP592 GM43681 3110062M04RIK ZFP9 MAPK1IP1 LDHAL6B HSPA12B GM13071 GM32856 B130034C11RIK GM37154 GM44777 FOXS1 QTRTD1 EARS2 GM42979 1200007C13RIK 9330151L19RIK AIRN GM42868 ZFP607B ANKK1 GM15445 UTP14B D630045J12RIK D930048N14RIK GM15884 GM43852 GM13648 GPR156 GM27003 PRDM15 CACNA1B GM12941 GM36266 GM43759 BC034090 GM37019 WDCP ZFP133-PS METTL16 5830487J09RIK ATP8B5 ASB14 5830408C22RIK DNM3 SNORA31 UGT2B1 GM44280 GM45114 1700029I15RIK D330041H03RIK XLR3A TMEM108 SLC25A35 AC163040.2 IGKJ5 2700081O15RIK YIPF7 2310058D17RIK GM42717 GM43375 5430416O09RIK GM5737 3110056K07RIK GM20045 4930402H24RIK ZFP366 9430015G10RIK HMGB1-PS8 GM23458 C79130 AC157822.3 AC107819.3 OLIG3 C030034L19RIK GM25747 GM28151 A230072C01RIK GFRA2 JMJD7 TNFRSF22 GM13830 SNHG14 GM43860 H2-M5 TRIM3 PLP1 POMT1 GM37074 AC158605.2 2700038G22RIK GM13111 LRTM1 AC159193.2 CRIP3 HIST2H4 TNR ZMAT4 GM26578 TTC41 GM26606 CYP51 GM16310 ZFP672 500 genes down-regulated by SARS-CoV-2 in mouse Heart cells at 7 dpi from GSE162113 GFP vs SARS-CoV-2 Mouse Heart Day7 GSE162113 down TIMM8B TBCA FCGRT CD34 NUDT2 YWHAQ NPTN FKBP7 SNX1 SLC1A1 ENPP3 ATP6V1A PDZD11 TPM4 RALA PF4 TMEM97 PDZD3 NDUFAF2 SCCPDH ANXA2 TUBA1A FAM162A NCK1 POLA1 ENPEP CALM1 CYB5R3 RARS PEPD ITM2A EIF4E NEDD8 PLS3 UAP1 ELOC DNAJC19 GGH LRRC1 DMXL1 MRPL35 MDH1 GLO1 APOOL HIBCH ADH5 ARHGAP18 TGDS CD55 OSGEPL1 DHRS1 CAV1 ISLR VKORC1 MYO1B RGS2 TM4SF1 MT-ND1 MT-CO1 METTL23 TSPAN6 FOPNL NDUFB2 ACOT13 PTPRZ1 CTSB KCNE1 GLRX SEC23B LGALS1 ANXA5 SDHD ALG14 BLVRA COMMD9 NDUFS4 TMEM45A CALCRL OLFML2A OSTC TPI1 MRPL51 PSMB7 MTERF2 MYH11 EPHB1 AKAP12 BMPR1A BMP7 MAPK8 IMPA1 SPARCL1 TMSB4X EDNRB ANKRD6 CTNNBIP1 RAP1A TMEM88 HACD1 PYCARD DHRS7C CASQ2 TRDN HSPB3 NPPA MB ITGA8 ACKR4 LRRC17 CAV2 SPTSSA UQCRB CD200 TNNC1 TUBA1B MYL2 TPPP3 SPARC MORF4L2 TMEM204 SEMA3C SH3BGRL NPNT UQCRC2 OGN CRIP1 ITM2C DPT PDE5A TAGLN CETN2 TCF21 DYNLT3 SMIM15 SDPR CHORDC1 NDUFV3 S100A16 CFL1 CDIPT COX6B1 TUBB2A DNAJA1 IGFBP7 DSTN CFDP1 VPS35 GNG11 NDUFA4 NDUFV2 EMC2 NDUFC2 ACYP2 RPS27L MRPS18C S100A10 PMP22 ATP5J2 GLOD4 COX14 CD9 CACYBP RGS4 SERPINI1 S1PR3 SNCG DUSP6 GNPDA2 HAT1 MRPL46 CMSS1 VAMP3 TXNDC17 MSRB2 CHMP5 TCEAL8 AP1S1 SARNP MTX2 SMIM20 MRPL13 IMMP1L MRPL42 ORMDL2 STK39 SDC2 ACTL6A EMG1 THYN1 NIF3L1 ATG5 SUSD5 TNFRSF21 MOB4 PDCD10 BZW1 MRPL32 SSR2 GTF3C6 KPNA3 MRPL1 UBA3 NAA20 STAG2 HSPE1 SEC23A TOMM5 TXNDC12 SKA2 CNN1 AKR1B10 MEA1 MSMO1 CSE1L BCHE CSRP1 MKKS MRPL47 SLIRP P2RY14 RXRG SSNA1 PDGFRL OTUD6B TMEM68 AHSA2 TMEM126B DCPS SNRNP25 TFPI2 BET1 SCGB1C1 MRPS11 SYNJ2BP THNSL1 EMP1 NOSTRIN SH3KBP1 RSU1 SRGN SEC61B RAB31 MYL9 CALM2 ARMCX1 ACTA2 CDC42EP2 FHL2 MLIP MCAM CDH13 DPYSL3 ACTG2 ANGPT2 IFNGR1 PGK1 HIKESHI TRAPPC1 SCFD1 VPS29 TIMM21 ANAPC10 QRSL1 PEX2 PET100 TEN1 POSTN SELENOF SNX6 HAUS8 TNFAIP8 FKBP14 COX20 CRLS1 IFT20 VTN UBA6 TMEM9B PRKRA DCUN1D2 ASAH1 COMMD1 COMMD3 CSRP2 DEGS1 STBD1 MFF COMMD10 NDUFAF4 TRMT2B DCAF4 RCBTB2 MED6 BBIP1 TMEM123 PTCD3 THEM4 MATN2 SMIM5 METTL22 CMC2 NDUFA11 FXYD6 TRIM13 PLN RNASEH2B ROBO2 INSIG2 NME6 TRDMT1 TRIQK RNF121 FUNDC1 MRPS22 NRAS CPQ GOLPH3L LUM IL13RA1 GSTT1 KIF6 ANGPT1 S100B CALU SENP8 DNAJC15 MGMT CCNG1 NDN PIN1 TCEAL1 ZC3HC1 LAPTM4B CCNC TMEM14C SDCBP COX7B ASPH HSD17B12 LAGE3 TMEM141 POLR3K TSPAN12 DCUN1D1 KLHL13 TUSC3 MFAP3 ECM2 TMX3 TOM1L1 QPCT HSPA13 CCDC90B TECR RFC3 COMMD2 CDR2 SACS NDUFS8 LHPP MRPL55 MRPL21 ARHGAP12 SNRPD1 MYCBP SCAI EEF1E1 MRPS14 LSM3 ZCCHC17 UQCC2 MRPL50 SDHAF4 SVIP COA6 C1GALT1C1 PDE1C LAMTOR4 AKR1C14 7-SEP MED21 ATP5F1 AKR1B3 HSPA12A MRPS16 PIGX B3GALT2 PDCL OMA1 SPRYD7 CNIH1 CXADR KCNMB1 PPM1F AAMDC SEC22A PRKCDBP MT-TI UROS SMIM11 PPP6C SMIM14 POLR1E WASHC3 PTGIS LSMEM1 GPR22 PKIA FAR1 LYRM7 SREK1IP1 EXOC6 MRPL22 NCBP2 TMEM242 DLD DPAGT1 10-SEP HTR7 NBEAL1 DNAJC24 GM38372 ITGBL1 S100A1 DUSP3 RPP21 FAM175B TSSC1 TEFM FASTKD2 SS18L2 MED28 NSMCE2 RPUSD4 EEF1AKMT1 NKIRAS1 AKTIP RNF141 TCEAL9 CBR4 NIPSNAP3B ASPN OLFR558 C1QTNF7 EMCN GM12002 GM17546 LDAH LDAH 1110059E24RIK ZFP54 ZFP260 1110059G10RIK ZFP931 SNAPC5 INTS14 CTLA2A GM45423 0610009B22RIK ATP6V0E PRRG1 GM15543 ELP5 6-SEP 2010107E04RIK 1810034E14RIK JAM3 TSTD3 1810037I17RIK NTM 2610001J05RIK AC163289.2 ZFP449 GM44250 4930523C07RIK CEP83 LRRC27 PCDHB16 COX8B BC028528 RAB28 AKR1E1 GM10039 ZFP719 FAM92A 3830406C13RIK AC160401.1 MOCS2 GPR37L1 6430562O15RIK 1700123O20RIK AC102435.3 SVBP PPFIA2 CEP19 GM43146 FAM212A GM45670 GM6419 PEA15A POT1A 500 genes up-regulated by SARS-CoV-2 in mouse Kidney cells at 7 dpi from GSE162113 GFP vs SARS-CoV-2 Mouse Kidney Day7 GSE162113 up SLC36A1 CEP250 CNTRL NINL PFAS SLC4A9 AKAP8 CACNA1D EP300 DDI2 FBXL12 NLRP6 BAIAP2L2 GRIPAP1 ERBB2 ARHGEF11 EPS8L2 LGALS4 NOS3 BRD4 AKAP8L UBE2I IGSF9 1810019D21RIK CNTD1 DALRD3 SF1 IKBKB BRF1 CCDC84 NFAT5 PLEKHG1 SRRT KHSRP IFFO1 TAOK2 ADCY7 MBD6 MAPK8IP3 THBS1 INPPL1 LDB1 USP19 GIGYF1 ZSWIM8 INF2 SNRNP70 SMTN HJURP SH3PXD2B MIB2 PER3 TNRC6C PTCH1 KANK3 NOTCH1 ABCC6 PKD1 EP400 FGFR1 CNOT3 NCOA3 SSH3 SEMA3F ALS2CL MYO19 ITPR3 LAMA5 TNK1 PRICKLE2 NAV2 LRP5 JAG1 PNN ABCA7 ELF4 RGS3 SAFB EDC4 CCDC9 CUEDC1 PHF12 NBEAL2 ST6GALNAC2 KMT2B RERE CREBBP HELZ2 FBRS PITPNM1 RGL2 ULK1 SBNO2 PLPPR2 ATG2A PRR12 DENND1C MYH6 STAT2 PLEKHA4 HAP1 SHANK3 VEGFA PABPN1 PLEKHG2 CAMTA2 RAPGEF3 CCNL2 DDX39B FAM160B2 USHBP1 TRIM46 KDM6B STARD9 CCM2L ADAMTS10 PRDM9 VAMP1 FUS ANO8 FOXK1 GGNBP1 MAPRE3 SLC25A27 CLCF1 NFKBIZ ZNFX1 ACIN1 SPRED3 MMS19 SEC24B RSRP1 AASDH PAN2 OGT ARGLU1 MSANTD2 NEAT1 LENG8 COL7A1 MARK4 SRSF6 MCC CD46 SMAD9 SFSWAP MLXIPL LMTK3 ADAMTS6 IL15RA ZCCHC2 RNF31 CEP131 CYS1 PRPF39 FNBP4 AFAP1L2 FIRRE LRRC45 KIFC2 SP100 STX16 PRRC2C TNRC6B TPRA1 PNISR SRRM2 ACHE MOB3C PHACTR4 GTPBP2 TRIM26 ACTN1 SRSF11 SRSF5 RCOR3 SLC25A42 KLHDC8B ATF7IP ZKSCAN3 DENND3 JARID2 SPRY4 FANCA GRIK5 KIF5A ASPG TNFRSF25 ZDHHC1 DOT1L MDM4 MFSD2B TRIM11 ROBO3 WIPI1 NUDT8 AP5Z1 CD33 CHKB FAM193B ANKRD11 MAN2C1 USP36 HOXC4 HELZ ANKZF1 ZBTB10 ZCCHC7 DPM1 NDOR1 MEF2D TEP1 ULK3 AKAP13 COL27A1 JAK3 HDAC7 TANC1 SKIV2L CRY2 TSPYL2 INPP5K ADCY6 FHOD1 LMBR1L ARHGEF15 DOCK6 ARAP3 TNIP2 SLC12A3 NPR1 VAMP2 SEMA4G PER2 ECE1 CLCN2 EWSR1 PLXNB1 SETD7 ARID1A KDM4A SEMA6A KMT2A SMARCC2 DAB2IP TRPM4 ABCC10 CBX7 MROH7 PITPNM2 ZFP609 NOTCH3 CRTC2 RPS6KB2 RBAK RANBP10 PARP4 NSD3 ERN1 ARNT PKN3 TOP3B ARHGEF1 PLCG1 COL16A1 MAP2K7 ARHGEF2 JOSD2 NYNRIN KANSL3 POGZ ATXN2L NFRKB RBM33 FOXJ2 TANC2 GGA3 ARID3B HMG20A ZBTB39 EPS15L1 MED13L BAHCC1 GSE1 SLC25A37 HIVEP1 MUM1 AFAP1 PHRF1 ARHGAP21 ZCCHC14 DIDO1 SZT2 SVIL TNRC6A LIMK2 GRAMD1A LARGE2 MAP4K2 GPATCH8 ZSCAN26 KMT2E BAZ2B PHF21A MYOM1 SUGP2 RBM5 SPACA6 CAPN15 GJC1 TCHP CPEB3 GRIP2 FRYL PPOX KMT2D FBXL20 RFX1 GBA2 MPRIP GABBR1 ODF2 TCTN1 SIDT2 H2-Q5 RBM25 BAZ2A SAFB2 ZFC3H1 LUC7L2 HOXA3 CLASRP RRNAD1 MLLT6 CIZ1 GAN LRP4 ARHGEF17 HOXD4 TNS2 SYNE3 SLC4A3 FAM219A UVSSA YBX2 DUSP11 PDE4C RGL3 BRD3 SRRM1 NKTR DNAL1 PROSER1 CLK3 TPCN2 TLE2 CABIN1 CLK2 KLC1 TNXB E4F1 MAU2 WNK4 PPP1R12B HDGFRP2 KCNC3 CROCC KRI1 MINK1 ATP5SL PRPF40B SNAPC4 CNTROB DZIP1L FIGN MIIP ATXN7 RTKN ACRBP PCSK4 GM43858 ZFP579 SULT5A1 SH3D21 CPSF7 LUC7L MED12 TAF4 SLX1B PCGF2 METTL17 BRD8 PITPNM3 SRCIN1 INTS6L ANKRD16 NRBP2 KMT5C DTX3 DENND6B HIP1 SNED1 KAZN ATXN7L2 CFAP65 4933439C10RIK RGS11 PPP4R1L-PS DVL3 ZNRF1 GM35339 SLC2A4RG-PS GM44597 GM42937 GM10804 ADGRA2 B230303O12RIK E230016M11RIK GM16348 GM37206 TTLL10 1810017P11RIK AI838599 DUSP15 GM12940 BC037034 A330023F24RIK 1810017P11RIK AI838599 DUSP15 GM12940 BC037034 A330023F24RIK AI480526 GM43597 MAPK15 MAPK1IP1 GM42979 9330151L19RIK TRIM3 TTC41 AC154347.1 AU020206 MIR5125 KRBA1 AC160637.1 DLG5 KCNT1 SBSN ZFP512B TRIM39 8430422M14RIK TBX3OS1 ZKSCAN7 SUPT20 D630044L22RIK GM45632 BC024386 TMEM44 PPP2R3D ZFP462 GM17193 INSRR AC160405.2 ANKRD24 1700034H15RIK A730017L22RIK GM20605 MAP3K12 4930426D05RIK AC147634.1 4833420G17RIK 4933427D14RIK CRAMP1L A430105I19RIK POT1B D930015E06RIK ZFP865 GM13563 1700029J07RIK A430110L20RIK GM17491 GM20342 ZFP467 A230050P20RIK ZFP384 ZFP707 TMEM198B GM12992 GM12121 GM43413 4933408B17RIK 0610005C13RIK GM37090 GM45250 GM20100 GM45838 GM37893 PHYHD1 NOVA2 AC079680.3 KLHL20 GM43609 A730011C13RIK CCHCR1 GM11611 500 genes down-regulated by SARS-CoV-2 in mouse Kidney cells at 7 dpi from GSE162113 GFP vs SARS-CoV-2 Mouse Kidney Day7 GSE162113 down DCTPP1 UBL5 SLC10A2 TIMM8B ERICH4 TBCA SUMO3 NUDT2 SPINK1 YWHAQ COMT AADAC HIST1H1C TINAG MME MPP5 ANKS4B MIPEP NDUFAF2 XPNPEP2 GTF2F2 TM2D3 STOML2 GRPEL1 HSP90AA1 FAM162A HMOX1 CALM3 CALM1 TUBA1C CTSD TUBA4A SDF2 ABCG2 NDUFB9 RARS HSBP1 NEDD8 ELOB PTGES2 ELOC LNPEP TMBIM4 MRPL35 MDH1 UBE2E1 TM2D2 SCRN3 PSMB1 2210016F16RIK FARS2 TPMT CLDN10 FBXO8 ADH5 FAHD1 YARS2 WDR34 NDUFB6 NXT2 DEFB29 PSMA2 RPS20 TBCB RPL37A UQCR10 NINJ1 FBXO36 CRYM LURAP1L SMPDL3A NDUFB2 RPL30 RPL39 ACOT13 COPS9 RPLP1 RPS14 RPL27A MAL2 PDIA6 CHID1 SNRPB LEPROT TMED9 SRD5A1 CCT5 NDUFB5 PNP MRPL12 POMP SPR AP2S1 DERA ATP6V1F SDHD METTL9 NDUFAF3 PRDX1 NDUFS4 MYDGF PDIA5 NME1 IDH1 OSTC MICU1 PRDX3 LDHA TPI1 PRELID1 PSMB7 BAD MIOX PSMD6 QPRT COX7A1 HSF2BP FABP7 SAMD9L TMED6 RNF7 SPTSSA UQCRB YBX1 AKR1A1 ATP5G3 ATP5J ANAPC13 MRFAP1 NDUFA3 CHCHD2 RPS19 UQCRC2 CYB5A BCAP31 COX7A2 EIF3I SNRPD2 RPL26 CTSH PPIB RPN1 NDUFA13 GABARAP COX8A MRPL20 NDUFS6 PTP4A2 CETN2 ATP5H NDUFB3 NDUFB11 SRP14 DYNLT3 CNBP PSMB4 RPL18A JTB NDUFA2 LAMTOR1 RAN ROMO1 NDUFV3 NDUFC1 CFL1 MPC2 COX6B1 NDUFA1 DNAJB1 CFDP1 VTI1B VPS35 GNG11 NDUFA4 ARL1 MSANTD4 NOP10 NDUFC2 CHCHD1 RPS27L MRPS18C ATP5J2 GLOD4 TMEM256 GPX4 COX14 MIEN1 CACYBP FBXO40 SPP2 GNA14 TMEM258 DPY30 OST4 PIGF ATRAID DPM3 MRPL34 CYB561D2 PDZK1IP1 POLR2G MRPL46 LAMTOR2 ATP6V1C1 TXNDC17 CHMP5 CHCHD4 TMEM205 TMEM208 CUTA PFDN2 PRDX4 CKB AP1S1 MTX2 TMX1 RABAC1 CCDC124 MAGOH COPS5 MRPL42 ORMDL2 PSMD10 SAR1A VMP1 UQCRQ PIH1D1 THYN1 NDUFA12 ATG5 SSR4 FAM96A PCMT1 AMD1 MCEE NIT2 ETHE1 SPCS1 HOXB7 SSR2 MRPL17 HSPE1 NDUFA9 RPL32 RAB1B SF3B5 TOMM5 FKBP4 KRCC1 MEA1 MSMO1 ATP5E MKKS SLIRP TMEM27 APOBEC2 NUDT1 DCPS SNRNP25 BET1 MRPS11 SLC35A1 GINM1 CCDC91 COA7 CSTB RSU1 SEC61B CLIC1 UQCRFS1 UQCR11 SERP1 SARAF COX6C CALM2 UGT3A2 PRDX2 VPS45 TRAPPC1 PFDN1 COPZ1 AASDHPPT SCFD1 RER1 TRAPPC4 GATB COPS3 SEM1 GTF2H5 PET100 RPE SSU72 RNF5 BSG PSMD5 SELENOF UXS1 STX8 SF3B6 SEC22B SPG21 SNX6 FKBP11 FARSB COX16 ZNRD1 FMC1 IFT20 TOMM22 UBA6 SNRNP27 TMX2 WDPCP CMPK1 AURKAIP1 BUD31 COMMD1 ACAT1 COMMD3 CNPY2 COMMD6 CSRP2 MFF PTER THEM4 FAM173A BOLA1 ASNA1 POLE4 NUDT14 MRPL54 NDUFA11 RNASEH2B SELENOK ACOT9 NME6 TRDMT1 PGP ATG10 ORMDL1 FIS1 DERL1 FUNDC1 MRPL40 CPQ GALK2 SLC46A1 SMU1 ACMSD SULT1C2 FAM151A PIN1 PNO1 TIMM50 THAP4 XRCC5 CCNC RPS4X TMED3 RHOC SELENOT SELENOH SELENOM COX7B TMEM70 AK1 RPS3A1 FAM213A DYNLRB1 CHCHD3 MRPL30 TOMM7 COMMD4 NSDHL TRAPPC2L POLR3K CHCHD6 NDUFB8 DGCR6 COMMD2 NAA38 NSMCE1 NDUFS8 TIMM17B YIF1B SNRPD1 ATPIF1 EEF1E1 MRPS14 MRPL57 CENPX UQCC2 COA6 C1GALT1C1 BLOC1S5 CRIPT LY6A OAF LAMTOR4 2310039H08RIK CYP2C69 D8ERTD738E ATP5F1 MRPS16 SPRYD7 BDH2 ELOF1 NUS1 PYCRL TPK1 MINOS1 NCBP1 DPH3 TAF9B PKNOX1 CFAP36 CCDC51 FAM220A MRPS28 PPP6C TIMM22 MRPS24 TMEM222 2810428I15RIK 0610007P14RIK MRPL45 SDHAF1 CHMP6 UBE3A POLR2I SMIM7 NPHP1 TMEM242 MRRF TOR2A TUBB2B LYRM4 NENF RPP21 FASTKD2 MED28 E2F5 TMEM216 MRPL36 NNAT EEF1AKMT1 FBXL4 DLEU7 OARD1 CALML4 MKRN2OS AKR1C21 ZFP35 GM3716 INSC DHRS7B BC004004 BOD1 AKR1C21 ZFP35 GM3716 INSC DHRS7B BC004004 BOD1 1110059E24RIK 0610009B22RIK ATP6V0E ELP5 2010107E04RIK 1810037I17RIK AKR1E1 FAM92A GM9800 1700037C18RIK GM4952 CYP2J5 MFAP1B ARL6 2410015M20RIK BC031181 ADGRG4 HENMT1 TMEM41A FAM45A TMEM167 POLR1D 0610012G03RIK 1110065P20RIK 1500011K16RIK B230118H07RIK CDPF1 PRORSD1 PIGYL TMEM128 AC121965.1 CYP2J11 HPRT BC026585 RPL7L1 NDUFAF8 OLFM3 AFG1L 1110008P14RIK DCDC2A PEX7 GM19541 500 genes down-regulated by SARS-CoV-2 in mouse Lung cells at 7 dpi from GSE162113 GFP vs SARS-CoV-2 Mouse Lung Day7 GSE162113 down DPP4 HSPA5 VCAM1 DDX10 SNX1 ITGB1 EIF2S1 MME COPB1 ATP6V1A TLR4 TMEM97 SCCPDH GTF2F2 ADAM9 HSP90AA1 LARP7 CTNNB1 NCK1 POLA1 ENPEP HEPH COPB2 AOC1 TARS CRK CANX AASS CHP2 SLC30A7 INTS4 PES1 STOM PLS3 HSPA8 PAICS MYNN NR3C1 SCP2 ARSK ARHGAP18 SIAE ADK POLR2B BPIFB1 SLITRK6 CP SDC1 RGS2 REPS2 SCGB3A1 MT-CO1 CFH CCDC80 PTGFR SLX4IP SEMA3A POF1B INPP4B CCL8 AIF1 PRNP STT3A PDIA6 C1QC ENPP4 CHID1 C1QA PDIA4 CCT5 PNP MACC1 SCARB2 CTSB MGST1 SEC23B SLC1A3 C1QB CCT8 HGF TMEM45A CCR2 DPYD MMP19 PRDX3 SPATS2L LDHA TPI1 PSMB7 SGCD ENPP5 ST8SIA6 BMPR1A AZIN1 STK3 COL5A2 ABCE1 IMPA1 COL14A1 TMOD3 LRRC8E SPARCL1 MMP3 NUCB2 IRF4 UMPS COLEC12 SMC2 MAD2L1 MASTL ADIPOQ BPIFA1 RETN CFD ENPP6 CCL17 GBP4 FOLR2 IFIT2 HEPACAM2 VCAN GBP2 SAMD9L TLR3 GLT8D2 ITGA8 ATP13A4 DGKB NEGR1 SCN3A C1QTNF3 SCN7A GSTM5 MORF4L2 OGN LAMP2 DPT MYH10 SERPINB9 DDR2 CETN2 DYNLT3 CCT3 BLMH DSTN ANXA1 TVP23B CFDP1 VPS35 MSANTD4 CETN3 CD36 WDR45B OAT SSR3 ACADSB CNTN1 CACYBP PI15 ART4 SRPX KCNE4 BMP5 LRRK2 PLA2R1 MAGT1 MOB1A HAT1 GTF2E1 TMEM33 ATP6V1E1 CHMP5 PJA2 HSP90B1 PSMD10 SUCLA2 SDC2 SAR1A ATG5 GJA1 BUB3 BZW1 VAMP7 SLC39A10 SNX4 ST13 HDHD2 MMGT1 EPRS NAA20 NARS EPHA7 SEC23A DNAJB4 GPBP1 NCOA4 CKAP5 PTPRD CSE1L ZMPSTE24 NEDD1 ASNS CREM SPPL2A ASCC3 TMEM252 F13A1 TFF2 TFRC PDGFRL RP2 OTUD6B PTGR2 STX19 C6 CFI VPS41 LAMP3 SEMA3E PRPS2 RPL22L1 TTC3 APPL1 DNAJC3 CCDC91 CD83 CCDC47 NOSTRIN NUDCD1 RSU1 CALM2 ACTR2 FLRT2 CDH13 HSPA1B ITGA6 HC GOSR2 COPZ1 SCFD1 SUGT1 ANAPC10 PEX2 ADGRE1 DARS POSTN GTF3C3 GNAI3 YIPF1 APMAP COPG2 SNX6 COPA FARSB PLRG1 FAM32A RNF13 UBA6 ZDHHC13 SLC35F5 GALNT1 MCFD2 ALDH3A2 ASAH1 CAPZA1 ACKR3 CCT6A ANXA4 CHMP3 STBD1 TRMT2B RCBTB2 SLC10A7 ERAP1 SMIM3 TMEM123 P4HA1 DHX29 PLA2G4A PPAT HNRNPC ACP2 UTP6 PSMD2 FXYD6 COG6 SMAD2 RNASEH2B FAM91A1 GMFB EXOC3 ROBO2 SLC26A3 LIG4 TEX15 GOLM1 LPP LIN7C RDH11 FXR1 TRIQK TMEM168 EIF5A2 SLC9A9 TFPI PAK1 PRKDC GOLPH3L LUM VPS50 IL13RA1 RFC1 HACD4 RAB7B LEP STAM2 EXOC4 POGLUT1 SMU1 HTR2A RNF4 S100B CALU RCN1 GCSAM CCNG1 PNO1 SKIV2L2 NUP205 WDR92 XRCC5 CASP12 RPS4X CXCL15 SDCBP DSE PDHA1 SMC1A METAP2 MFSD14B MAOB CHCHD6 FEZ1 MANBA DZIP3 PGAP1 KLHL13 TUSC3 PPP1R3C MFAP3 CRNKL1 CD109 TES ECM2 QPCT HSPA13 LIMS1 RRP15 RAB27B EMB GOLIM4 DYNC2LI1 MRPL50 RBBP9 C1GALT1C1 ECHDC1 SEMA3D OXCT1 GBP9 C1S1 VWA5A MS4A6C SERPINA3N CAR3 7-SEP ADH1 SCD1 EDA2R ARMCX3 PHKB PDCL RPS6KA6 DNAJC10 CXADR TTC33 ENSA ZHX1 GSAP SCAPER NHLRC2 DCTN4 TAF9B CHM NIFK CCSER2 CD59B CES2G RAD50 WDR61 EIF1AX AU021092 0610007P14RIK GGTA1 DYNC1I2 COA5 FAR1 UBE2W SLC2A13 TWSG1 LYNX1 COPS2 ATAD1 SKAP2 MR1 MTMR6 NIPA1 EIF2S2 FER DLD 10-SEP KLHL9 LPAR1 CDKL5 ITGBL1 USP46 RNGTT TTC27 TRMT5 FAM175B COG5 KLHL7 NNAT PHEX FREM1 TMTC4 ZFYVE16 MGL2 4930578C19RIK ABCA8B ZFP35 KBTBD4 ST6GALNAC3 ZFP35 KBTBD4 ST6GALNAC3 1110059E24RIK INTS2 ZFP260 LYZ1 PCDHB16 AKR1E1 3830406C13RIK TMEM167 B230118H07RIK CDKAL1 PCDHB7 CHIL1 9230104L09RIK ARF2 F8 CAPN6 AC153958.1 ZFP712 KCNE2 3632451O06RIK TCAF2 CNTN4 AC153368.1 ZFP146 PCDHB8 SKP1A ISPD ENOX2 ZFP518A GUCY1B3 PCDHB13 TGOLN1 CKMT1 OLFR1033 CYP2J6 UBE3C D3ERTD254E GM6472 ZFP790 IGSF10 FCRLS PCDHB14 SYTL4 GM15501 AW112010 PCDHB19 4930486L24RIK H60C ADAM5 OIT1 1810011O10RIK KLRA4 PCDHB22 D6WSU163E GM830 PDXDC1 GM17473 1110012L19RIK 500 genes down-regulated by SARS-CoV-2 in human Nasal Epithelial Cells cells at 24 hpi from GSE162131 untreated v SARS-CoV-2 WildType Human NasalEpithelialCells 24hpi GSE162131 down GDF15 HSPA5 SQSTM1 STX3 TRIB3 PCK2 VHL LSAMP NPC2 COPB1 EPB41 SLU7 GOLGA7 ANXA3 LYN SLC5A1 CRYL1 HLA-B ADAM9 SARS RNF41 HMOX1 CEP68 RBCK1 ING4 TARS EPB41L5 CLIP4 ABCG2 CNDP2 HERPUD1 FYN MGAM CAT ANO6 STC2 SPART NEU1 ZC3H12C TIMM44 ADHFE1 ASF1A BRI3 VLDLR BPNT1 CPT1A FECH ZFAND1 N4BP2L2 BTF3 RASEF LINC01133 TGFB2 PIGR ASS1 A2ML1 TTC9 SLC40A1 FGFR2 GULP1 MTRNR2L8 SH3BGRL2 S100P APLF AL035661.1 SNORD17 MTRNR2L12 ADH1C FNIP2 AC013264.1 TCP11L2 RPL30 SNORA79B BCAS1 SNORA73B CDC14B KRT15 SAMD12 ACOT13 RIMS1 ABLIM1 KIAA1143 ABCA1 RPS27 FTL CD24 RNASEL SLC3A2 DHRS7 RETREG2 SLC1A5 PYCR1 ALDH1L2 CREG1 RNASE1 GPNMB PAQR4 BCAT1 PRDX1 SH2D4A GRB10 LGALS3 CLDN7 EPS8 GLDN SNORD3C ALDH9A1 PSMB2 MTHFD2 CA11 RNU4-1 IGFBP3 MARS KLF15 TRAK2 SERPINF1 ABCG1 MYCL IMPA2 PLPP2 CHMP4C FAM84B TRIM16 KITLG BMP3 ATF3 FRAT2 GABARAPL1 NUCB2 CNGB1 OCA2 OSBPL1A ZCWPW1 DACT2 TBL1X BSPRY GATM ULBP1 TMEM45B PSAT1 APOL6 C1R SUCNR1 NAMPT SLC7A11 WARS EPHX1 PSME1 CLIC4 PCBP2 MAP1LC3B FMO1 NFKBIA EIF2S3 ATP6V0E1 UBL3 MED18 COX7A2L EIF3E EFEMP1 NACA CTSH ALDH1A1 PRDX5 NUPR1 DDR2 BNIP3 TMEM50B CD74 TSC22D3 TOMM20 PRPF19 SAP30L JTB EMC3 ATF4 TALDO1 JDP2 LBH MYLIP GTF2B IGFBP5 ACADSB KCNF1 DDIT3 MBP LINC00847 TMEM150C MS4A8 CHAC1 ZNF263 TSPAN31 ANP32A ZNHIT3 HMGB3 NQO1 YPEL5 LAMTOR5 TMEM230 WDR83OS FAM107B SSR2 EPRS PFN2 NAA20 BEX2 NARS SF3B5 FOLR1 MXI1 DNAJB4 MKRN1 PPM1H EFNA1 TNFSF15 PIR CREBRF KLHL24 ANKRD13A DENND5A NECAP1 SLC6A9 ASNS DNASE2 PCGF5 SLC1A4 TFRC ALDH3A1 AARS IARS PELI2 LY96 ANKRA2 GYPC VPS41 SUMF1 LPGAT1 AMFR GARS CRIM1 XPOT FNIP1 TM6SF1 MIA2 ETS2 GPT2 PMAIP1 SLC28A3 HLA-DRA RRAGD ANP32B KLHDC2 C1S PXK PIK3AP1 RPL23A MSRB1 CNPY3 ALDH2 BLVRB EIF1 SERP1 SIX3-AS1 BMF VLDLR-AS1 CBS PRKAG2 SESN2 GRPEL2 TRIM16L BACH1 NCOA7 SLC31A1 RIT1 TNIP1 GK LARS CARS KIT CLCN3 YARS CTSF STX7 ERP29 SEPHS1 HTATIP2 PHGDH CALCOCO2 SULF1 FAM32A MTRNR2L6 WTIP AIG1 ALDH3A2 CHMP1B CCPG1 BUD31 ACKR3 ACAA2 ABHD4 TTLL1 ZNF268 MED6 ANKMY2 ZNF680 PGPEP1 PANX2 HBP1 DKK3 DTX4 ZNF160 ITPR1 RPS6KA2 MCCC1 SELENOK ATP6V0A4 GCLC FUT3 TRPM7 LRRN1 AZGP1 TSPAN15 TXNRD1 BACE2 CBX7 CNTNAP2 ZBTB21 ZFAS1 GSR DAPK1 EIF4EBP1 TMEM192 POLR2F ZFAND5 FBXO32 NDUFA4L2 SLC19A2 TMEM106B BCL2L13 ZNF133 MTHFD1L GPC3 TBC1D15 GCLM SERPINF2 ADH1B AKR1C1 HAX1 RCN1 AIFM2 TSEN15 SHMT2 HRK TOP1MT SEC63 CAVIN2 NOP53 PRDX6 SLC48A1 GPX8 SPSB1 SLC25A20 LHFPL6 ADGRF1 SEL1L3 EIF3L TOMM7 C6ORF48 SLC25A38 LPIN2 SPIRE1 TUBE1 KIF21B UHRF1BP1 TTC39B ADM2 AIF1L LANCL1 CPE DOCK11 RSL24D1 PYROXD1 TRPC1 CEBPG BTF3L4 DGCR6 FBXO34 KIAA0232 ABHD14B ZMAT5 DHRS3 DCAF11 ZNF84 OSER1 PSPC1 SLC20A2 AL355075.4 SNORA74A TMEM9 SNORA49 RNU4-2 SNORA73A SNORD3A MACROD2 TBC1D16 SNTB1 RETREG1 SNORD3B-2 CD99L2 VWA5A LAMTOR4 SLC7A2 EIF3M ZNF845 ADCY9 RAB3B PHPT1 AGA KIAA0513 DDX49 ZNF766 RHBDD1 LYPD6B HRASLS5 YPEL2 SLC35A3 RORA FBXW4 MBTD1 SNORD94 ZNF394 POLR1E RDH10 ULK4 COA5 MPPED2 SH3GL3 DCUN1D4 MR1 EIF2S2 ZNF559 KCNK15 GUCY1A2 TCEA3 GALNT13 SCARNA10 ARHGAP20 BEND6 ZNF480 MKX MRPS18B CEMIP2 MAP1LC3B2 CRBN ZNF844 ZNF229 CBSL UTP14C AKTIP DLK2 PHEX TMEM18 TMEM267 RHBDL1 CYB5D2 GPRASP2 BOD1 BOD1 LINC00365 AC026785.2 ZNF135 ERVE-1 SLC6A16 AL357153.1 ILF3-DT PEX11A LINC01564 SINHCAF AL590617.2 ZNF22 AC010980.2 CLDN20 AC093911.1 SNORD3B-1 FP671120.3 EIF2S3B OSER1-DT AP001207.3 FP236383.2 AP002360.1 FP671120.1 FP236383.1 C4ORF46 TUBA4B AC007325.4 VIPR2 EIF3J-DT FP236383.3 TMEM101 C11ORF1 RF00004 500 genes down-regulated by SARS-CoV-2 382-deletion mutant in human Nasal Epithelial Cells cells at 24 hpi from GSE162131 untreated v SARS-CoV-2 Mutant Human NasalEpithelialCells 24hpi GSE162131 down FCGRT GDF15 HSPA5 TMEM37 STAT3 SQSTM1 STX3 TRIB3 PCK2 LSAMP COPB1 ANXA3 LYN NDRG1 CRYL1 HLA-B ADAM9 KCNQ1 SARS RNF41 ANXA11 HMOX1 CEP68 UBTD1 RBCK1 ING4 HLA-C TARS EPB41L5 CLIP4 ABCG2 CNDP2 HERPUD1 FYN PABPC1 MGAM PEPD EXOSC5 CAT ANO6 STC2 SPART NEU1 SEPHS2 ZC3H12C TIMM44 ADHFE1 ASF1A BRI3 VLDLR CPT1A ZFAND1 BTF3 RASEF BPIFB1 RPS16 MUC21 LINC01133 TGFB2 PIGR ASS1 TTC9 FGFR2 GULP1 MTRNR2L8 SH3BGRL2 SNORD17 PNRC1 MTRNR2L12 MTRNR2L1 ADH1C FNIP2 CDC14B CYBRD1 KRT15 ACOT13 RIMS1 TACSTD2 ABLIM1 LCN2 ABCA1 RPLP1 SYBU FTL CD24 RNASEL SLC3A2 DPP7 PGD DHRS7 SH3BP2 BST2 HLA-E SLC1A5 PYCR1 ALDH1L2 AC093627.4 RNASE1 PAQR4 CES1 BCAT1 PRDX1 SH2D4A GRB10 LGALS3 CLDN7 CBR1 EPS8 SNORD3C MTHFD2 CA11 MIR3648-2 MIR3648-1 COLGALT2 IGFBP3 HINT3 MARS KLF15 TRAK2 SERPINF1 ABCG1 MYCL IMPA2 PLPP2 CLDN4 CHMP4C THEM6 PROSER2 FAM84B SULT2B1 TRIM16 GIPC1 SLC7A5 TPD52L1 SLC7A1 FZD1 KITLG BMP3 ATF3 FRAT2 GABARAPL1 NUCB2 OCA2 PTPRU ZCWPW1 DACT2 CEBPB TBL1X BSPRY GATM ULBP1 SECTM1 TMEM45B CFD PSAT1 APOL6 C1R NAMPT ADM MUC5B SLC7A11 WARS EPHX1 TRIL FTH1 CLIC4 PCBP2 RPS28 MAP1LC3B CHMP4B EIF3G FMO1 RNF187 EEF2 GSTP1 KLHL5 UBL3 PXDC1 COX7A2L EFEMP1 CTSH ALDH1A1 PRDX5 NUPR1 DDR2 BNIP3 CD74 TSC22D3 NDFIP1 PRPF19 RGCC SAP30L JTB ATF4 TALDO1 SLC39A1 JDP2 LBH MYLIP TMEM260 HCK CYP2S1 IGFBP5 GPX4 KCNF1 DDIT3 MBP TAGLN3 LINC00847 TMEM150C BAMBI CHAC1 HMGB3 NQO1 YPEL5 FAM107B EPRS PFN2 NAA20 BEX2 NARS SF3B5 FOLR1 MXI1 DNAJB4 PPM1H VEGFB PIR CREBRF ITPKC KLHL24 PRRX2 ANKRD13A GALNT18 DENND5A SLC6A9 RNFT2 CACNG6 ASNS DNASE2 PCGF5 DLL1 MUC20 SLC1A4 TFRC ALDH3A1 CYP1B1 RTN4RL1 AARS IARS LINC01003 GYPC LPGAT1 METRNL TULP4 GARS CRIM1 XPOT TPRA1 FNIP1 TM6SF1 MIA2 ETS2 GPT2 PMAIP1 SLC28A3 HLA-DRA RRAGD VAT1 ANP32B KLHDC2 MDK C1S JADE2 PXK PIK3AP1 MSRB1 CNPY3 ALDH2 BLVRB EIF1 SERP1 CDKN1B BMF VLDLR-AS1 CBS PPTC7 PRKAG2 SESN2 CHST2 OSGIN1 GRPEL2 TRIM16L BACH1 APOE SPRR2E UBE2V2 SLC31A1 RIT1 TBXAS1 TNIP1 STX11 LARS CARS CLCN3 YARS XBP1 CTSF B4GALNT4 STX7 ERP29 TOM1 SEPHS1 HTATIP2 PHGDH CALCOCO2 SULF1 FAM32A MTRNR2L6 ALDH3A2 CHMP1B CCPG1 ACAA2 ANXA4 MPST PARM1 TTLL1 MED6 DGCR6L DDA1 HDAC5 TRAPPC6A GNPTG NUDT14 SMPD1 PANX2 HBP1 DKK3 TBC1D9 ITPR1 RPS6KA2 SELENOK PPARA GCLC FUT3 KEAP1 LRRN1 MEGF9 AZGP1 TSPAN15 TXNRD1 RRAS2 CNTNAP2 ZBTB21 GSR DAPK1 EIF4EBP1 ZFAND5 FBXO32 CYB561A3 NDUFA4L2 SLC19A2 TMEM106B MTHFD1L GPC3 TBC1D15 CYP2W1 GCLM ADH1B AKR1C1 LMO4 HAX1 RCN1 TNC AIFM2 SIAH2 SHMT2 HRK TOP1MT SEC63 CAVIN2 NOP53 SLC48A1 GPX8 SPSB1 ANTXR1 LHFPL6 MRPL23 FBXO2 SEL1L3 LPIN2 SPIRE1 TUBE1 KIF21B UHRF1BP1 TTC39B ADM2 AIF1L HS6ST1 PMVK TFCP2L1 CPE DOCK11 RSL24D1 PYROXD1 CEBPG BTF3L4 DGCR6 FBXO34 KIAA0232 ABHD14B DHRS3 DCAF11 CNST PSPC1 SLC20A2 AL355075.4 SNORA74A RNU4-2 SNORD3A MACROD2 TBC1D16 SNTB1 RETREG1 SNORD3B-2 CD99L2 SLC7A2 ADCY9 PHPT1 AGA KIAA0513 SLIT3 DDX49 PLA2G16 CCNY RHBDD1 LYPD6B B3GALT6 HRASLS5 YPEL2 SLC35A3 RORA ZNF394 RDH10 COA5 MPPED2 DCUN1D4 EIF2S2 ZNF419 KCNK15 ROM1 GUCY1A2 TCEA3 SHC2 SCARNA10 GID4 ARHGAP20 BEND6 MKX CEMIP2 CRBN KRBOX4 ZNF229 CBSL MPPE1 AKTIP DLK2 TMEM267 RHBDL1 CYB5D2 TMEM25 BOD1 BOD1 LINC00365 AC245100.6 CERS4 AC026785.2 SLC6A16 SINHCAF AL590617.2 AC010980.2 SNORD3B-1 FP671120.3 AP001207.3 FP236383.2 FP236383.1 AC007325.4 VIPR2 FP236383.3 RF00004 MIR3687-2 C15ORF59 NSMCE3 FP671120.4 ALDH1L1-AS2 C12ORF65 ARHGAP22 AC010536.1 LINC01836 IL36RN PRRT1B 500 genes up-regulated by SARS-CoV-2 in human Lung Organoid cells at 24 hpi from GSE148697 mock vs SARS-CoV-2 Human LungOrganoid GSE148697 up NKX3-1 ADAMTS1 JAK1 EEF1A1 BIRC3 CCL2 VCAM1 ANPEP STAT3 TMPRSS2 SQSTM1 UBD SPINK1 EPB41L2 DNAJC11 TNF CXCL5 DDX5 THY1 CXCL10 EPB41 ACE2 CXCL16 TPM4 IFITM1 FABP1 COL4A1 ANXA2 ACSL5 IGSF3 HLA-B CLCN6 CTNNB1 NFKB1 SERPINE1 FYCO1 FLT1 DNASE1 COPB2 PTX3 TP53 FN1 NR3C2 TRAF3 B2M FBN2 HHLA2 CXCL2 HKDC1 PPIA MUC13 SIPA1L1 NEO1 MYO10 CP CXCL1 CXCL6 SLC22A23 CEBPD DUSP16 CGNL1 ZEB2 THRB RPL41 RPS24 GPX2 ELF3 OSMR KIAA1217 CFH CCDC80 PLCB4 ZNF827 ANKRD33B RGL1 FOXQ1 SGPP2 EHF RPL7 RPS27 ANKRD52 TNFAIP2 PIEZO1 IL4R THBS1 RFX5 TGFBI TYMP B3GNT7 ITGA5 SDC4 ALDH1L2 AREG LDLR FKBP5 FADS1 ITGA1 CARD6 EIF4G1 PDIA5 CDKN2B HP KCNMA1 TYMS G0S2 PTGS2 AKAP12 IGFBP3 SLC2A6 MYC COL5A2 MANF EP400 FAM20A MTOR BCL9L WWC1 FGF11 SFRP1 GABARAPL1 ESRRB TNFRSF11B HIF1A TFE3 BCL3 CEBPB SBNO2 COLEC12 SAA1 OAS3 CFB TNFRSF9 TAP1 CCL20 CTSS MYBPHL IFIT3 C3 CXCL3 APOL6 CCR1 CTSK C1R COL3A1 FGG CLDN2 SOCS3 TREM1 NFKBIE NAMPT GBP2 PARP9 CASP4 SERPINA3 RNF213 PARP14 PCDH10 F3 PLAU CSF3 SCUBE2 ITGA8 MICALCL BTG2 FTH1 ETS1 SHANK3 ZFP36 IER3 IRF1 SGK1 TGM2 HMGCS1 ICAM1 NFKBIA KLHL5 JUNB SLC34A2 CTGF VEGFA MAT2A PLIN2 SERPINE2 HLA-DQA1 ACAT2 MYH10 C11ORF96 TAPBP FHL1 SH3PXD2A EFNB1 DNAJA1 RPL36AL UQCRHL LRG1 SAT1 KIF26B COL6A3 RRAD ZC3H12A MAB21L2 TRPC3 ISM1 FAM167A PPP1R15A CSF1 TRIM22 KCNE4 MXRA5 HMCN1 BMP5 GPR111 TNFAIP3 IL23A S1PR3 MUC1 NEURL3 LIF BHLHE40 MAFF NFKBIZ STIP1 VMP1 PRPF3 HOXB7 LAMB1 IL17C PCSK5 MORC4 SLCO2A1 NEAT1 EFNA1 SAMD4A IK HDGF HIVEP2 ZNF337 C15ORF48 RND1 ROBO1 IL1R1 ZNF211 PRRT2 STAP2 TAP2 APOA2 PNPLA3 SLFN5 TRIM14 MAP3K8 RIPK2 CTSE OLR1 IRAK2 TESC PVRIG GSDMB IL32 CFI LPGAT1 CASC3 ST3GAL1 CKAP4 PSTPIP2 CRIM1 ASH1L LAMC2 SRRM2 CD83 PLK2 RELB CHST15 NFE2L3 CLUHP3 TICAM1 CX3CL1 PATL1 SP140L C1S SOD2 MOB3C PARP8 OPTN CFLAR C8ORF4 SERPINA1 MYL6 CASP8 LTB RASGRP1 ACTA2 HERC2P2 RASSF4 CDC42EP2 IL1RAP BCAR3 XYLT1 CCAT1 PAPPA LAMP5 HHIP LOXL2 IGF2 CXCL14 KANK4 COL12A1 ITGB6 ADAM19 ADAM8 PLSCR1 ADAMTS9 SPRY4 ABCA12 NCOA7 MYO16 SLC6A14 C12ORF36 ANGPT2 IFNGR1 IFNAR2 IKBKE TANK TNIP1 MAP4K4 MRAS SPEN ROS1 PARP1 TFEB IFNGR2 NFKB2 SNW1 CYTH1 SULF1 WIPI1 AHNAK CDC37 CDC42SE1 BOC FIP1L1 LOC202181 ANKRD11 LTV1 DNAJB11 FGA MIR600HG FBXO10 PIM2 BCL6 DAPP1 CHI3L2 RBM6 MICAL3 DST ABR FDPS PPARD TRIP10 HILPDA SLC7A6 MMP7 APOB CHDH ECE1 SMARCC2 PRSS12 PDE9A MAST2 BACE2 SETD5 IFT57 MSRB3 WISP1 TNFRSF10B ATG4A PRKCG UBR4 ZNF720 ZNF641 DNAH5 MTHFD1L ZFHX4 HUWE1 SLCO3A1 SERPINA4 HGD PLA2G2A COL5A1 ACSS2 SLC2A14 SYNPO PEA15 TNC ALDH1A2 HNRNPAB TCOF1 AFP HSPA9 NFKBIB COL16A1 AHCYL2 TMEM51 PNKD NANS OSBP CELSR3 SCAF4 PIP5K1A DDX24 ABTB2 KIF21B LRRN3 SLC25A37 HIVEP1 MICAL2 KCTD11 TENM3 ANKRD50 SULF2 RAB15 IGF2BP2 SBF2 GFRA1 COL22A1 KAT6A SVIL GPATCH4 SLC26A9 TRIO CWC25 ZBTB7A PRRX1 SIPA1L2 EIF4G3 MPRIP GABBR1 TTC28 SF3B2 EDA2R ZRSR2 SVEP1 DOCK4 JAKMIP2 DNAJC12 MGAT5 LRP4 HOXD9 SLIT3 COL23A1 MGAT3 SSBP3 TMEM63A RAB3IP EIF2B2 IL8 LOC646278 KIF2A CNTNAP1 PIEZO2 LOC102723726 DIEXF IGF2BP1 DACT3 SCG2 TBX4 ALPK2 ZNF589 BEND3 MIR3916 PHF8 ERVK13-1 ADAMTSL1 ARNT2 IGFN1 IGFN1 LOC102724608 LOC101928706 AC007966.1 C1R-2 LOC101928451 ZNF547 SNORD84 LINC00908 LOC101927940 LOC101928814 LOC101929792 LOC102723546 LRRC55 KNOP1 HOTTIP RP11-3P17.4 HOXD11 CCDC40 LOC102723808 LARP6 LRRTM4 LOC102724554 WWC3 LOC100506379 ASB4 HOXD10 332 proteins enriched in AP-MS using various SARS-CoV-2 proteins as bait from Gordon et al. (2020) from Gordon et al. (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. (Nature, 4/30/2020) NDFIP2 NUP210 GLA SRP19 F2RL1 EIF4H FOXRED2 TIMM10B DCTPP1 ADAMTS1 PPIL3 DCAKD CSNK2B EMC1 CEP250 CHPF2 AP2A2 RTN4 IMPDH2 TIMM8B TARS2 CEP112 TBCA CEP350 ERMP1 MPHOSPH10 RAB2A HDAC2 FAM8A1 CEP43 ATE1 ATP13A3 OS9 GCC2 NIN GDF15 PSMD8 PIGS CNTRL FKBP10 IDE CDK5RAP2 NINL COL6A1 ERLEC1 ERO1B ATP6AP1 TRMT1 HYOU1 TCF12 ABCC1 DDX10 ZC3H7A HECTD1 MDN1 TRIM59 PRIM2 LARP1 GHITM LOX ERGIC1 CISD3 CHPF COMT SUN2 SLC25A21 ETFA RPL36 DNAJC11 WASHC4 PTBP2 NUP54 FKBP7 PRKACA NEK9 SMOC1 ATP5MG CSDE1 SLC27A2 EXOSC3 MAP7D1 ITGB1 PKP2 LMAN2 MOGS LARP4B BCKDK SLC9A3R1 AKAP8 EXOSC8 SCAP TUBGCP2 TBK1 TOR1A NUP62 ACADM RRP9 GCC1 DDX21 SAAL1 NPC2 TLE5 ATP6V1A MIB1 RHOA UPF1 RIPK1 NOL10 DPY19L1 TUBGCP3 HEATR3 SLU7 JAKMIP1 GOLGA7 PDZD11 PUSL1 ACAD9 GOLGA3 PPT1 TIMM9 RALA NGDN CEP135 CYB5B YIF1A TYSND1 AP3B1 AATF TOR1AIP1 TMEM97 RETREG3 COLGALT1 CWC27 RBX1 PVR NDUFAF2 ZC3H18 SCCPDH SLC30A9 PLEKHF2 MIPOL1 GTF2F2 PRRC2B HOOK1 FBLN5 FBXL12 ECSIT MRPS2 ADAM9 GNG5 TM2D3 STOML2 CENPF ACSL3 SEPSECS GRPEL1 GPAA1 SRP54 SIGMAR1 FAR2 RNF41 GOLGA2 UBAP2 USP13 AP2M1 NUP58 NPTX1 MRPS5 COQ8B CIT TIMM29 TLE3 PIGO PITRM1 LARP7 ZYG11B RAB8A MRPS27 FAM162A POLA1 HMOX1 CEP68 UGGT2 GPX1 BRD2 ALG5 FYCO1 RAB18 FASTKD5 SNIP1 RAB14 BCS1L BZW2 TAPT1 AGPS TMEM39B NGLY1 GIGYF2 POFUT1 PMPCA GGCX DNMT1 RAP1GDS1 GRIPAP1 SELENOS INHBE EIF4E2 FAM98A RDX PABPC4 MARK3 ERP44 QSOX2 ATP1B1 CUL2 PLOD2 ARL6IP6 ZDHHC5 NUTF2 RBM28 POGLUT2 SDF2 CLIP4 MRPS25 AASS TLE1 CSNK2A2 UBAP2L NARS2 CYB5R3 PRIM1 MFGE8 MTARC1 FBN1 REEP5 NDUFB9 MYCBP2 CLCC1 SIRT5 POR SLC30A7 PLD3 ALG8 MEPCE SRP72 NUP214 INTS4 NLRX1 RAB7A USP54 RBM41 HSBP1 PABPC1 PCNT FKBP15 PCSK6 RAE1 PLAT PMPCB POLA2 MARK1 TIMM10 WFS1 NUP88 FBN2 PRKAR2B BRD4 ELOB GNB1 G3BP1 AAR2 CRTC3 AKAP9 VPS39 MOV10 EXOSC2 EXOSC5 NUP98 VPS11 ZNF318 SBNO1 ALG11 STOM MAT2B EDEM3 POGLUT3 NSD2 HS2ST1 SIL1 TBKBP1 MTCH1 PRKAR2A UBXN8 TMED5 IL17RA MARK2 CCDC86 ANO6 GORASP1 AKAP8L ARF6 RAB1A NDUFAF1 ZNF503 PTGES2 DCAF7 GOLGB1 NAT14 THTPA ELOC DNAJC19 RAB10 SCARB1 CHMP2A SLC44A2 SLC30A6 REEP6 DPH5 GGH TOMM70 GFER STC2 BAG5 SPART HS6ST2 G3BP2 RAB5C PDE4DIP NEU1 PLEKHA5 ERC1 C1ORF50 184 proteins up-regualated at 0h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 0h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) MPHOSPH10 APC CTSL MAP7D1 RBL2 RNF2 EZR RETREG3 LAP3 HSPB1 PLCB3 FBL ARHGEF11 FRMD4B ARHGEF12 TLN1 MED14 NCOA5 EIF4B OSBPL6 PARD6B PATJ PEAK1 OTUD7B RPLP1 C2CD2L TMEM184B SRSF9 MBD1 LMNA EIF3B WDR13 PLK1 ARHGAP29 ITSN1 EPS8 SORT1 ABCB1 MYC ABCF1 HMGA1 SRSF1 BCL9L PROSER2 FAM83G ITPR3 SAFB NCAPD2 RPS28 HNRNPM PCBP1 MATR3 EFNB1 VPS35 ATP2B1 SSR3 CBX3 SLC18A3 TMX1 DDX18 HAVCR1 DKC1 PITPNB LEO1 CWC22 FXR2 ZDHHC23 SRSF7 MAP1B SETD2 GAS2L1 MTFR1L SIK1 TRA2B PRKD2 MCM7 WDHD1 LMNB2 BET1 BCL10 NIPBL THRAP3 SRRM2 RHBDF2 N4BP1 PYGL SON SRSF12 PRKCD ZPR1 PSMD11 CAMSAP1 NADK SEC22B TRAPPC10 C9ORF78 AHNAK DDX54 KIF13A NSRP1 AKAP10 CPSF3 EEPD1 PHLDB1 DDX39A HDAC7 NOP56 LUZP1 MDC1 TTC7A KAT5 IFT43 PTK7 ACACA RALGAPA2 DCLK1 ZBTB21 EVA1A TP53BP1 PRKDC TBC1D15 UBXN7 PPM1B MAP3K2 PEA15 RBM17 NSD3 SUDS3 ZC3HC1 BYSL CD2AP MAGED2 DPF2 GAPVD1 RASAL2 VPS26B PHIP OSBPL10 RBM15 SVIL CDK13 GPATCH8 TJAP1 CDK14 FRYL DOCK7 PHKA1 HIRIP3 BAZ2A SAFB2 SF3B2 PDLIM7 SERBP1 GIT1 CXADR COL15A1 SMG8 ZMYND8 SRRM1 ZMYM3 NKTR GNL3L UBE4B TCP11L1 CLASP2 R3HDM1 GARS1 FAM160A2 RIF1 ARMCX4 BAG2 WASHC2A WASHC2C DLG5 SYTL4 SLAIN2 KDM2B SLC35C2 H2AX GKAP1 KRIT1 SIK1B OXSR1 NIBAN1 277 proteins down-regualated at 0h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 0h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) NUP210 PTPN14 MAPK3 RB1 APC LARP1 NEK9 MAP7D1 LARP4B MACF1 EPB41L1 AHSG TOR1AIP1 ZC3H18 ELAVL1 ANXA2 TUBB4B TTN DNMT1 TP53 UBAP2L POLA2 NPM1 NUP98 MARK2 PLEC SPTBN1 MAPK1 RAB11FIP2 ARHGEF12 TLN1 EIF4B SH3D19 SLC4A4 YAP1 MARCKS ZEB1 TJP1 CEP170 TAB2 SRRT KHSRP C2CD2L STMN1 GSK3A TBC1D9B AKT1 GIGYF1 LMNA ZYX PLK1 TOP2A EZH2 LMNB1 SLC16A1 KIAA0930 CTNND1 KIF2C SH2D4A SMTN CDCA2 TPX2 ANLN NCAPH EPS8 CDC20 HJURP ARHGAP23 MKI67 RAPH1 DTL TOPORS LLGL2 CDYL MAVS EP400 BCL9L ARHGEF5 ZNF687 PRICKLE2 MAP2K3 PRC1 KIF13B ECT2 PBK RACGAP1 CHAF1A AAK1 BMPR2 PCBP1 RAPGEF2 RPS10 VIM SP3 ADRM1 TNS3 PHLDB2 VCL KIFC3 PPFIA3 BRD1 FLRT3 IRF2BPL CDC42EP3 HAT1 DKC1 NELFE RPS6KA3 TMPO ANKRD39 CWC22 SLC25A46 WDR11 TAF7 HIVEP2 CDCA7 EMD SFSWAP ZC3HAV1 RGS10 DYNC1LI1 MCM4 HAUS6 LMNB2 C1ORF174 GTF2I BBX ATRX BOP1 TWISTNB BOD1L1 THRAP3 SRRM2 LIMA1 HPS5 KHDRBS1 AKAP11 NONO ETV3 PTPN1 UFD1 RANBP2 CTCF ARAF SEC16A SPP1 C12ORF45 PPHLN1 AHNAK ALKBH5 CCZ1B DDX54 PHC3 MTA2 WDR44 AHCTF1 NSRP1 MSH6 RBBP6 NT5C2 DNTTIP2 NCOR2 STRN4 ZSCAN18 MYO9B LUZP1 MDC1 CTPS1 SMPD4 FLNC FHOD1 NAP1L4 NCOR1 SSRP1 TRIM24 JMJD1C EHMT2 PCM1 IL6ST TP53BP1 PIK3R4 MAPK9 BCL2L13 RANBP10 ANKLE2 PPP2R5A PHF6 NCOA1 SYNPO KAT7 RBM17 AFDN TERF2 SUDS3 NUP188 TCOF1 RRP1B MLLT1 NOLC1 SNRPC ARHGEF2 MSL3 ATXN2L MED1 DCP1A DDX24 KDM2A ABTB2 GPS1 RPA1 CCDC6 AEBP2 IGF2BP2 APBB2 TBC1D4 CDK13 CLIP1 ARPP19 PDLIM4 C16ORF72 CWC25 PALLD OTUD4 RIPOR3 H1-3 H1-5 SEPTIN9 ATL3 LNPK DOCK7 ZC3H13 HIRIP3 HNRNPU DBNL TRIP12 XRN2 FNBP1 PDLIM7 DCDC2 RSBN1 ENSA SRRM1 NKTR SORBS1 RAB3IP DBN1 POM121 UBE4B FAM53C KLC2 SGTB WDR47 ZNF638 SHROOM2 CPSF7 CCZ1 DEPDC5 FAM122A POM121C FBXO46 IQSEC1 DNTTIP1 SNTB2 SURF6 MIEF1 PAPOLG AKTIP CLASP1 MAP7D3 WIPF2 RSL1D1 LRCH3 SLAIN2 SEPTIN7 TASOR CBX8 CUSTOS 318 proteins up-regualated at 2h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 2h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) MYH9 MPHOSPH10 HDAC2 RB1 ATP13A3 HSP90AB1 APC CTSL SPTAN1 VCP PKP2 RRP9 MACF1 MIB1 SLC26A6 TOR1AIP1 RETREG3 PKM ZC3H18 BRAF LAP3 STOML2 LARP7 FRMD6 SNIP1 NFATC2IP FBL DNMT1 NPM1 PPIG NUP98 PRKAR2A PLEC CHD1 ARHGEF12 TLN1 SAC3D1 MNAT1 NCOA5 EIF4B SLC4A4 PRKAA2 CYBRD1 FNBP1L TJP1 KIAA1143 NUMA1 SRSF9 EIF3B WDR13 TOP2A EZH2 SAP30 SLC16A1 STARD13 ITSN1 CDK1 EIF4G1 SORT1 NCAPG AKAP12 IWS1 CTNNA1 STK4 STK3 ABCF1 HMGA1 SRSF1 MTOR WWC1 PAK4 LSR ALPL MAP2K3 HNRNPH1 ARHGAP1 HERC2 CTR9 SAFB PSMA3 PACS1 SCAF1 OGFR LRCH4 FAM83D HELLS TIMELESS RNF213 DPYSL2 EEF2 RBBP7 LIMCH1 ALDH1A1 HNRNPUL1 MATR3 SRP14 TNS3 FNDC3B PRPSAP1 EEF1G FASN VPS35 PDCL3 NUCKS1 MYO18A VCL PGRMC1 RBM8A SLC18A3 FOXK1 BRD1 ACIN1 TAF12 DDX18 CDC26 HAVCR1 HDAC1 DKC1 PCBD1 SSB SKP1 RPS6KA3 BZW1 AKR1B1 PITPNB LEO1 WBP11 MFAP1 VGF ZDHHC23 MAP1B SURF2 KDM3B CLIP2 CDH6 PRKD2 MTCL1 MCM4 SLC20A1 MCM7 HNRNPA2B1 RPL22L1 UTP20 KIF1A EIF5B TWISTNB THRAP3 RSF1 SRRM2 RBM34 RCAN1 SH3KBP1 PYGL SF3B1 SON SRSF12 HIST2H2BF DPYSL3 RANBP2 OSTF1 EIF2AK4 CREB1 GNAS ARRB1 TXNL1 SAE1 PRPF6 USP39 TNFAIP1 SEC16A HACE1 DTNB C9ORF78 AHNAK CDC42BPB ACAT1 CCZ1B STK25 FIP1L1 DDX54 HNRNPUL2 MPHOSPH8 EPHA2 RBBP6 CEBPZ AKAP10 CPSF3 ZMYM2 RALY EEPD1 SYNE2 POLR2A FBXO10 STK24 NOP56 MDC1 TTC7A CTPS1 KAT5 RRP7A NAP1L4 PBRM1 PTK7 IGF2R SRF ELAC2 SSRP1 CCAR2 USP28 TNKS1BP1 DCLK1 RRAS2 SUZ12 ZBTB21 LRWD1 WDFY3 ATG2B TP53BP1 UBR5 RABGAP1 HUWE1 PSMF1 TBC1D15 SLC4A1AP UBXN7 GBF1 PPM1B PHF6 PEA15 RBM17 NSD3 ARNT GPSM1 BCLAF1 CCNH POLR3E PPIL4 BYSL CD2AP WDR70 VIRMA ARHGEF2 FLNB DCBLD2 SLC4A7 GTF3C4 DPF2 DDX24 KDM2A ARHGEF28 CARHSP1 PHIP DENND4C ICE1 RBM15 GPATCH8 ZFR AP3D1 UBE2O NMD3 BCKDHA ZBTB7A SEPTIN2 FBXL20 PHKA1 SUPT6H CHD3 PDCD5 HIRIP3 PID1 BAZ1B TRIP12 BAZ2A SF3B2 PRPF4B PDLIM7 SERBP1 EFR3A NCBP1 SMG8 ZMYND8 SRRM1 PDS5B DOCK9 UBE4B SUGP1 PHACTR1 MOB1B CROCC GCFC2 PI4KA CCDC12 TCP11L1 CLASP2 SRSF10 ILF3 WDR91 CCZ1 R3HDM1 PPP6R3 GARS1 FAM160A2 IQSEC1 SPIRE2 PAPOLG DDX55 INTS10 SYTL4 ZNF22 H2AX TASOR ANP32D RANBP3 OXSR1 H4C1 NIBAN1 SMAP WDR55 419 proteins down-regualated at 2h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 2h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) NUP210 PTPN14 RSRC2 RB1 APC HECTD1 LARP1 EPB41L2 SUN2 MAP7D1 PKP2 LARP4B MACF1 EPB41L1 AHSG ABL1 TOR1AIP1 ZC3H18 ELAVL1 RUNX1 BAG3 CIT ABI1 POLA1 TTN DNMT1 TP53 MARK3 ZDHHC5 CRK UBAP2L MYCBP2 CLCC1 ARHGEF11 MEPCE NUP214 POLA2 NPM1 PXN CRTC3 USP15 MARK2 CCDC86 GSK3B FRMD8 PLEC PLEKHA5 RPS6KB1 ATXN2 ALB EIF4B SRGAP1 AUTS2 SLC4A4 YAP1 PKP4 PTPN13 RICTOR MARCKS ZEB1 TJP1 KIAA1671 CEP170 NEDD4L TAB2 SRRT TAGLN2 KHSRP C2CD2L TMEM184B STMN1 GSK3A TBC1D9B HS1BP3 AKT1 GIGYF1 TBC1D10B LMNA ABCC3 PPP1R12C ZYX PLK1 TOP2A ARHGAP31 LMNB1 KIAA0930 ARHGAP29 CTNND1 STARD13 KIF2C BUB1 ORC1 SMTN SNAPIN SLCO4A1 CDCA2 TPX2 ANLN NCAPH EPS8 HJURP MKI67 CDYL EP400 BCL9L TONSL PROSER2 KIAA1522 CEP170B ARHGEF5 PRICKLE1 PRICKLE2 STIM2 MAP2K3 DGCR8 PTPRU MEF2A KIF13B ZFAND3 ULK1 SMARCA1 EPN1 CHAF1B NCAPD2 ECT2 PBK CHAF1A ADAR TRAFD1 BMPR2 TNS1 SNRK POLDIP3 RPS10 VIM SP3 TNS3 FNDC3B RBM7 PHLDB2 SUB1 NUCKS1 GEM DGKQ GFAP TNFAIP3 LCE3D TP53I11 PPFIA3 BRD1 SOWAHC ACIN1 GPKOW PPP1R18 BCOR TOMM34 NELFE TMPO ANKRD39 SLC25A46 PLEKHH2 NUFIP2 ID2 CLIP2 PHYHIPL CSRP1 CDCA7 EMD SFSWAP ABL2 ZC3HAV1 PIKFYVE RGS10 DYNC1LI1 AJUBA KATNA1 MAP1S MTCL1 PSIP1 SLC20A1 NHS HAUS6 LMNB2 SPAG9 BBX CNNM3 KPNA6 REEP4 TWISTNB HERC1 BOD1L1 PNISR THOC2 THRAP3 SRRM2 LIMA1 AFF4 BAZ1A RHBDF2 OPTN SEC61B KHDRBS1 AKAP11 NONO ADD3 SOBP STK17A ETV3 PUM1 RANBP2 CAMSAP1 KDM1A MAP3K7 TOM1 ARAF NUP153 LSM14A SEC16A SPP1 PPHLN1 AHNAK ALKBH5 ASAP1 USP36 EML4 WDR44 NSRP1 U2SURP DNTTIP2 C2CD4C GOLGA4 ARID1B AKAP13 PHLDB1 SYNM BAIAP2 NCOR2 PRRT3 KLC4 SMAP2 MYO9B CC2D1B RAPGEF1 LUZP1 MDC1 KANK2 SRCAP CTPS1 MICAL3 SLC9A1 FLNC TSSC4 PPP1R12A AGFG1 MTUS1 ARID1A SEMA6A NCOR1 NCOA2 KMT2A JMJD1C MAST2 RALGAPA2 DCLK1 NF1 RUNX1T1 EHMT2 PCM1 TNFRSF10B AMBRA1 WDFY3 TP53BP1 DCAF1 MAPKAP1 ERBIN EEF2K MAPK9 CNOT2 RFC1 RANBP10 ANKLE2 SCAF11 GBF1 CIAPIN1 AKR7L NCOA1 SYNPO MUS81 KAT7 AFDN PPP2R5D CCDC88A ABI2 MTDH REPS1 ANAPC1 SUDS3 ZC3HC1 TCOF1 RRP1B PMS2 NOLC1 CDK12 IREB2 ARHGEF2 ADGRG6 MSL3 EIF4ENIF1 ATXN2L MGA RUSC2 EPS15L1 KDM2A RPA1 LIG3 CPD CCDC6 DENND4C APBB2 ANK2 PHRF1 HCFC1 TBC1D4 WDR20 CAMSAP2 RBM15 PHACTR2 RAD54L2 CDK13 CLIP1 UCKL1 PDLIM4 C16ORF72 ZNF609 NEK1 PCF11 PALLD H1-2 H1-3 FAM53A H1-4 SEPTIN9 ATL3 LNPK DOCK7 KMT2D ZC3H13 HIRIP3 HNRNPU DBNL BAZ1B TRIP12 XRN2 TCF20 PLEKHA2 ZFC3H1 SIN3A RASSF8 MICALL1 DPYSL5 DCDC2 FMNL3 CXADR OSBPL11 LARP4 DMWD FRMD4A SNAP23 SRRM1 CHAMP1 ARHGAP39 SCAMP3 DBN1 STRIP1 CHTOP NELFA POM121 STK11IP ITPRID2 FAM53C WIZ PANK2 JPT2 KLC2 KRI1 PI4KA GPRIN1 BAG4 HABP4 WDR47 ZNF638 ZNHIT2 JCAD SHROOM2 WDR91 FAM122A MIDEAS POM121C MVB12B GRIP1 OSBPL3 PAK2 RIF1 SNTB2 SURF6 AKTIP TBC1D1 CLASP1 DVL3 RSL1D1 LRCH3 CRYBG1 SLAIN2 CDC23 RANBP3 CBARP CBX8 LCE3E BAP18 262 proteins up-regualated at 4h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 4h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) NUP210 HDAC2 ATP13A3 HSP90AB1 MACF1 MIB1 SLC26A6 RNF2 RETREG3 PKM ING5 BRAF STOML2 SNIP1 DNMT1 NUP214 RCC1 NPM1 PPIA PLEC PLEKHA5 TLN1 SAC3D1 RAI14 CYBRD1 FNBP1L TJP1 KIAA1143 C2CD2L CD2BP2 USF1 ZNF316 LEMD2 NUMA1 MBD1 RETREG2 TKT WDR13 TOP2A EZH2 SAP30 SLC16A1 KIAA0930 LGALS1 STARD13 EIF4G1 SORT1 NCAPG ZNF830 AKAP12 IWS1 CTNNA1 STK4 CDYL STK3 ABCF1 ACTB HMGA1 WWC1 PYGO2 HERC2 HNRNPK CTR9 RGS3 SAFB PSMA3 OGFR BRIP1 IFI16 TIMELESS DPYSL2 RPS28 HNRNPUL1 MATR3 PDCD4 SAP30L RNPS1 TNS3 CFDP1 PDCL3 NUCKS1 MYO18A VCL PGRMC1 RBM8A BRD1 ACIN1 TAF12 DDX18 TFPT HDAC1 DKC1 SSB SKP1 LEO1 USO1 CWC22 MFAP1 VGF ZDHHC23 HIST2H2AA3 MAP1B SRSF6 CDH6 SLIRP TRA2B MSI1 MCM4 MCM7 WDHD1 LMNB2 HNRNPA2B1 RPL22L1 UTP20 KIF1A EIF5B BOP1 THRAP3 RSF1 SRRM2 RBM34 RCAN1 RHBDF2 SH3KBP1 PYGL SF3B1 HNRNPA1 PUM2 DPYSL3 RANBP2 EIF2AK4 SPEN ARRB1 TXNL1 SAE1 PRPF6 USP39 TNFAIP1 STK10 SEC16A C9ORF78 ERCC5 FIP1L1 DDX54 HNRNPUL2 SUV39H2 CEBPZ AKAP10 CPSF3 ZMYM2 RALY SYNE2 MADD NOP56 MDC1 CTPS1 XPC KAT5 RRP7A EDC3 NAP1L4 PTK7 IGF2R RREB1 ELAC2 SSRP1 USP28 RALGAPA2 TNKS1BP1 RRAS2 SUZ12 SMC4 LRWD1 HSF1 ATG2B TP53BP1 UBR5 PRKDC HUWE1 PSMF1 SLC4A1AP GTPBP1 UBXN7 GBF1 PPM1B PHF6 PEA15 RBM17 BCLAF1 CCNH POLR3E PPIL4 MYBBP1A BYSL CD2AP CDK12 WDR70 VIRMA DPF2 DDX24 SPIRE1 KDM2A ARHGEF28 PACSIN3 RBM15 CDK13 GPATCH8 PCF11 BCKDHA ZBTB7A H1-5 SEPTIN2 USP20 PHKA1 SUPT6H CHD3 PDCD5 HIRIP3 PID1 BAZ1B TRIP12 BAZ2A DDX23 SF3B2 PRPF4B EFR3A NUP35 ZMYND8 SRRM1 ARHGEF40 ESYT2 COIL PDS5B RNASEH1 FBXO28 UBAC1 STK11IP WIZ SUGP1 BIVM CCDC12 ILF3 R3HDM1 PPP6R3 GARS1 FAM160A2 DNTTIP1 ZFYVE19 WASHC2A WASHC2C DDX55 SYTL4 SCARF2 KDM2B KRIT1 ANP32D RANBP3 OXSR1 NIBAN1 WDR55 MTMR1 TBC1D14 197 proteins down-regualated at 4h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 4h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) RSRC2 APC LARP1 SQSTM1 EPB41L2 NEK9 MAP7D1 LARP4B MACF1 AHSG ELAVL1 BAG3 CIT MYCBP2 NPM1 PRKAR2B NUP98 CCDC86 GSK3B PLEKHA5 ARHGEF12 SGTA AUTS2 YAP1 PKP4 ZEB1 CEP170 NEDD4L SRRT TAGLN2 STMN1 TBC1D9B HS1BP3 LMNA ZYX TOP2A CTNND1 BUB1 SMTN SLCO4A1 TPX2 ANLN EPS8 HJURP MKI67 AKAP12 CDKN1A ZFP36L1 ABCC5 EP400 MEF2A ZFAND3 PLEKHG3 ULK1 CHAF1B NCAPD2 PBK AAK1 TRAFD1 BMPR2 TNS1 JUNB VIM TNS3 FNDC3B RPS3 SUB1 NUCKS1 TNFAIP3 NPDC1 PPFIA3 MAPRE3 BRD1 ACIN1 PIH1D1 TMPO ANKRD39 MAP1B ID2 CLIP2 SRSF6 CDCA7 EMD ZC3HAV1 RGS10 KATNA1 DCP1B PSIP1 SLC20A1 HAUS6 HERC1 THRAP3 SRRM2 BAZ1A RHBDF2 OPTN AKAP11 SON SOBP PUM1 RANBP2 CAMSAP1 MAP3K7 NUP153 SEC16A SPP1 AHNAK ARID1B PHLDB1 NCOR2 PRRT3 KLC4 SMAP2 LUZP1 FLNC UCK2 NAP1L4 MTUS1 NCOR1 JMJD1C EHMT2 PCM1 ZBTB21 MIA3 PRR5 DCAF1 CNOT2 ANKLE2 AKR7L NCOA1 SYNPO RBM17 AFDN MTDH BCLAF1 REPS1 ANAPC1 RECQL4 TCOF1 PMS2 NOLC1 IREB2 EIF4ENIF1 ATXN2L MGA PFKFB2 TMEM131 DENND4C AEBP2 PHRF1 HCFC1 TBC1D4 PDZD8 UCKL1 DOCK5 ATL3 LNPK DOCK7 DBNL HDGFL2 OSBPL11 LARP4 FRMD4A NUP35 SNAP23 SRRM1 NKTR CHAMP1 PHF3 DBN1 STRIP1 STK11IP ITPRID2 WIZ JPT2 KLC2 SGTB PI4KA SYNC BAG4 CLASP2 JCAD SHROOM2 WDR91 DEPDC5 FAM122A YEATS2 MVB12B RIF1 CLASP1 RSL1D1 LRCH3 CRYBG1 SLAIN2 CDC23 CBX8 RELCH 300 proteins up-regualated at 8h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 8h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) MYH9 MPHOSPH10 HDAC2 ATP13A3 HSP90AB1 HECTD1 LARP1 SQSTM1 LARP4B MACF1 SLC26A6 RNF2 EZR TOR1AIP1 RETREG3 PKM ING5 BRAF HSPB1 LARP7 FRMD6 SNIP1 PLCB3 DNMT1 NUP214 RCC1 NPM1 PPIG NUP98 MAP3K1 PPIA PLEC CHD1 SPTBN1 PLEKHA5 EI24 TLN1 SAC3D1 RAI14 CYBRD1 FNBP1L TJP1 KIAA1143 CD2BP2 USF1 DDX41 ZNF316 NUMA1 RETREG2 TKT WDR13 SYNGR2 TOP2A EZH2 SAP30 SLC16A1 KIAA0930 FKBP5 STARD13 CDK1 EIF4G1 KIF23 SORT1 RAPH1 NCAPG ZNF830 AKAP12 IWS1 CTNNA1 STK4 CDYL STK3 MAVS ABCF1 HMGA1 HEATR6 SLC4A2 HERC2 HNRNPK CTR9 SAFB PSMA3 RERE SCAF1 OGFR FAM83D IFI16 TIMELESS PML DPYSL2 RPS28 EEF2 RBBP7 ALDH1A1 MYH10 HNRNPUL1 MATR3 SAP30L VPS35 PDCL3 NUCKS1 MYO18A VCL PGRMC1 RBM8A SLC18A3 BRD1 ACIN1 TAF12 DDX18 TFPT CDC26 PPP1R18 HDAC1 DKC1 PCBD1 PTDSS1 SSB SKP1 BZW1 TMPO LEO1 USO1 RPL29 CWC22 MFAP1 VGF MAP1B SURF2 SETD2 CDH6 SLIRP MSI1 LBR MTCL1 MCM4 MCM7 WDHD1 HNRNPA2B1 RPL22L1 UTP20 KIF1A EIF5B BOP1 BOD1L1 THRAP3 RSF1 SRRM2 RBM34 MVB12A PYGL PUM2 HIST2H2BF DPYSL3 RANBP2 OSTF1 EIF2AK4 ARRB1 TXNL1 SAE1 PRPF6 USP39 TNFAIP1 STK10 C9ORF78 CDC42BPB CCZ1B STK25 ERCC5 ASAP1 IRF2BP1 SUV39H2 LIN37 KTN1 NT5C2 CEBPZ PTPN12 CPSF3 ZMYM2 RALY EEPD1 SYNE2 STK24 MADD NOP56 MDC1 XPC KAT5 RRP7A PSMD2 NAP1L4 PTK7 IGF2R SRF RREB1 ELAC2 SSRP1 USP28 RALGAPA2 TNKS1BP1 RRAS2 SUZ12 ZBTB21 LRWD1 HSF1 ATG2B TP53BP1 PRKDC RABGAP1 HUWE1 SLC4A1AP GTPBP1 SCAF11 UBXN7 GBF1 PPM1B PHF6 POU2F1 MAP3K2 PEA15 RRBP1 RBM17 GPSM1 BCLAF1 CCNH POLR3E PPIL4 MYBBP1A BYSL MLLT1 CDK12 WDR70 VIRMA GTF3C4 DPF2 GAPVD1 DDX24 SPIRE1 KDM2A ARHGEF28 PACSIN3 AEBP2 OSBPL10 RBM15 CDK13 C1ORF52 GPATCH8 PCF11 TJAP1 RBM10 NMD3 BCKDHA ZBTB7A FRA10AC1 H2BC11 SEPTIN2 SUPT6H CHD3 PDCD5 HIRIP3 PID1 BAZ1B TRIP12 SF3B2 PRPF4B PRR14 EFR3A ZMYND8 SRRM1 NKTR SORBS1 DSN1 PDS5B RNASEH1 FBXO28 RAD50 UBAC1 WIZ SUGP1 BIVM YLPM1 CCDC12 ILF3 CCZ1 PPP6R3 GARS1 DNTTIP1 SPIRE2 CLASP1 DDX55 RSL1D1 KDM2B ANP32D RANBP3 OXSR1 NIBAN1 SMAP WDR55 TBC1D14 FGFR1OP 347 proteins down-regualated at 8h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 8h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) PTPN14 RBL1 STAT3 APC HECTD1 LARP1 EPB41L2 NEK9 MAP7D1 PKP2 LARP4B RBL2 AHSG ABL1 ZC3H18 ELAVL1 RUNX1 BAG3 CIT TP53 ZDHHC5 CRK MYCBP2 MEPCE CRTC3 USP15 MARK2 CCDC86 GSK3B FRMD8 PLEC CHD1 PLEKHA5 RPS6KB1 ARHGEF12 ALB SGTA EIF4B AUTS2 SLC4A4 YAP1 SH3RF1 PKP4 PTPN13 KIAA1217 MARCKS ZEB1 ABLIM1 CEP170 ARID5B NEDD4L SRRT C2CD2L RIPOR1 STMN1 TBC1D9B HS1BP3 GIGYF1 CAD LMNA ZYX PLK1 TOP2A ARHGAP31 BUB1 CDC6 SMTN TPX2 ANLN NCAPH UNC13B HJURP MKI67 DTL MLF1 FAM83H CDKN1A MYC ZFP36L1 CDYL EP400 MITF HMGA1 PROSER2 CEP170B EEF1D PRICKLE1 PRICKLE2 BIN1 PTPRU MEF2A CCDC9 ZFAND3 PLEKHG3 ULK1 AKT1S1 CHAF1B NCAPD2 PBK ARHGEF39 MASTL TRAFD1 BMPR2 TNS1 JUNB LIMCH1 PPP1R14A VIM CD97 ERRFI1 TNS3 FNDC3B PHLDB2 NUCKS1 GEM SCML2 TNFAIP3 FILIP1L PPFIA3 FOXK1 MAPRE3 BRD1 IRF2BPL ACIN1 MBD4 NUP107 PTBP3 CUL4B ARGLU1 NUFIP2 SAMD4A ID2 CLIP2 ATAD2 ABL2 ZC3HAV1 RGS10 DYNC1LI1 MAP1S MTCL1 PSIP1 SLC20A1 HAUS6 KIF3B CNNM3 REEP4 TWISTNB HERC1 PNISR THRAP3 SRRM2 BAZ1A RHBDF2 OPTN KHDRBS1 AKAP11 NONO SON ADD3 SOBP ETV3 PUM1 TERF2IP RANBP2 UBE2J1 CAMSAP1 MAP3K7 NUP153 SEC16A SPP1 PPHLN1 AHNAK CDC42SE1 MFF MTA2 EML4 DNTTIP2 AKAP10 ZMYM2 ARID1B AKAP13 PHLDB1 SYNM NCOR2 PRRT3 NBN SMAP2 MYO9B LUZP1 VPS13D KANK2 NCAPH2 MICAL3 RAF1 ABR TSSC4 UCK2 DDX42 NAP1L4 MTUS1 HDAC4 ARHGAP5 ARID1A SEMA6A NCOR1 MAGI3 RALGAPA2 DCLK1 EHMT2 TSC2 PCM1 MIA3 AMBRA1 DCAF1 ERBIN PRKDC CNOT2 PCYT1B ANKLE2 RALGAPB PARP4 NCOA1 SYNPO RBM17 AFDN CCDC88A BCLAF1 MGMT REPS1 ANAPC1 ZC3HC1 TCOF1 RRP1B PMS2 NOLC1 CDK12 ARHGEF2 MAGED2 SLC4A7 EIF4ENIF1 ATXN2L MED1 MGA RASAL2 WAC EPS15L1 GPATCH2L GPS1 RPA1 PFKFB2 CPD TMEM131 CCDC6 DENND4C PHRF1 HCFC1 OSBPL10 TBC1D4 NCBP3 CAMSAP2 RBM15 CDK13 SLTM UCKL1 CCDC61 ZNF609 NEK1 PCF11 HNRNPA3 CDK14 H1-2 CBY1 RIPOR3 H1-3 FAM53A ATL3 LNPK DOCK7 EIF4G3 ZHX3 MPRIP ZC3H13 HNRNPU DBNL BAZ1B TRIP12 RBM25 TCF20 SF3B2 PRPF4B ZFC3H1 RASSF8 MICALL1 FMNL3 HDGFL2 OSBPL11 LARP4 FRMD4A GAB1 SNAP23 SRRM1 NKTR ZNF622 SCAMP3 DBN1 STRIP1 STK11IP ITPRID2 FAM53C WIZ PANK2 JPT2 SRBD1 FAM76B KLC2 SGTB PI4KA GPRIN1 ELFN2 BAG4 HABP4 CLASP2 ZNHIT2 JCAD SHROOM2 WDR91 BUD13 FAM122A YEATS2 URI1 MVB12B FAM160A2 PAK2 RIF1 PLEKHG4 TBC1D1 MAP7D3 CCDC8 DLG5 CSDC2 CRYBG1 SLAIN2 CDC23 CBX8 TASOR2 RELCH ATRIP 355 proteins up-regualated at 12h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 12h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) MYH9 MPHOSPH10 HDAC2 ATP13A3 HSP90AB1 HECTD1 SPTAN1 PRKACA RRP9 MACF1 EPB41L1 RNF2 RETREG3 PKM ANXA2 LAP3 HSPB1 LARP7 FRMD6 SNIP1 FBL DNMT1 TRIM28 NUP214 RCC1 NPM1 PRKAR2B PPIG HERPUD2 MAP3K1 PPIA PLEC CHD1 PTK2 PLEKHA5 ERC1 TLN1 SAC3D1 SLC4A4 COBLL1 PKP4 RALGPS2 CYBRD1 FNBP1L TJP1 KIAA1143 RPLP1 CD2BP2 SYMPK USF1 DDX41 ZNF316 NUMA1 AKT1 RETREG2 LMNA TKT WDR13 SYNGR2 PLK1 TOP2A EZH2 SAP30 SLC16A1 KIAA0930 FKBP5 CDK1 EIF4G1 GAPDH CLTA KIF23 ARHGAP23 RAPH1 AKAP12 IWS1 CTNNA1 STK4 STK3 ABCF1 HMGA1 SRSF1 HEATR6 MAP2K3 HERC2 HNRNPK ELF4 SAFB PSMA3 PRKACG PACS1 SCAF1 OGFR FAM83D IFI16 TIMELESS DPYSL2 RPS28 EEF2 PCBP1 ALDH1A1 HNRNPUL1 MATR3 PDCD4 SRP14 SAP30L RNPS1 PRPSAP1 FASN PDCL3 ATP2B1 NUCKS1 MYO18A VCL PGRMC1 RBM8A FOXK1 BRD1 BABAM1 ACIN1 TAF12 DDX18 TFPT STK39 CDC26 PPP1R18 UCHL3 MBD4 HDAC1 DKC1 PCBD1 SSB SKP1 BZW1 TMPO LEO1 RPL29 DDB2 MFAP1 VGF ZDHHC23 MAP1B SURF2 SETD2 KDM3B CLIP2 CDH6 SLIRP TRA2B MSI1 MCM4 MCM7 DHX16 MAD1L1 ALYREF LMNB2 LIG1 SP100 HNRNPA2B1 BCL10 RPL22L1 NIPBL UTP20 KIF1A EIF5B ATRX BOP1 REEP4 PRKACB BOD1L1 PNISR THRAP3 RSF1 SRRM2 RBM34 RCAN1 VAT1 ANP32B RHBDF2 N4BP1 SH3KBP1 MVB12A ALDOA PYGL RNH1 HNRNPA1 PUM2 HIST2H2BF DPYSL3 PSMD11 RANBP2 OSTF1 EIF2AK4 SPEN ARRB1 TXNL1 SAE1 PRPF6 USP39 ZMYM4 TNFAIP1 STK10 SEC16A PPHLN1 C9ORF78 AHNAK ACAT1 CCZ1B STK25 ERCC5 FIP1L1 DDX54 ASAP1 IRF2BP1 HNRNPUL2 SUV39H2 RBBP6 CEBPZ AKAP10 ZMYM2 RALY SYNE2 STK24 MADD NOP56 MDC1 XPC NOL8 ABLIM3 RRP7A PSMD2 NAP1L4 XRCC6 PTK7 IGF2R SRF RREB1 ELAC2 SSRP1 CCAR2 USP28 MAST2 TNKS1BP1 DCLK1 RRAS2 SUZ12 SMC4 PCM1 ZBTB21 LRWD1 HSF1 ATG2B TP53BP1 DCAF1 PRKDC UBR4 HUWE1 SLC4A1AP UBXN7 GBF1 PPM1B PHF6 POU2F1 ACSS2 MAP3K2 PEA15 RBM17 MCM3 BCLAF1 CCNH POLR3E PPIL4 RECQL4 BYSL CD2AP CDK12 WDR70 VIRMA HSPA9 ARHGEF2 DPF2 DDX24 SPIRE1 ARHGEF28 PACSIN3 CARHSP1 PHIP RBM15 CDK13 C1ORF52 GPATCH8 RBM10 NMD3 BCKDHA ZBTB7A H2BC11 SEPTIN2 DOCK7 USP20 PHKA1 SUPT6H CHD3 ZC3H13 PDCD5 HIRIP3 PID1 BAZ1B TRIP12 SF3B2 PRPF4B SIN3A CHD9 EFR3A NUP35 SMG8 ZMYND8 SRRM1 ARHGEF40 ESYT2 PDS5B RNASEH1 RAD50 UBAC1 UBE4B STK11IP WIZ SUGP1 BIVM ATN1 CROCC YLPM1 CCDC12 RBMX2 PKN2 SRSF10 CCZ1 POP1 R3HDM1 PPP6R3 TIMM8A ARMCX4 SPIRE2 ZFYVE19 WASHC2A WASHC2C DDX55 ZNF22 KDM2B KRIT1 ANP32D RANBP3 OXSR1 H4C1 NIBAN1 WDR55 TBC1D14 404 proteins down-regualated at 12h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 12h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) PTPN14 UHRF1 RB1 RBL1 STAT3 APC HECTD1 LARP1 EPB41L2 NEK9 MAP7D1 LARP4B MACF1 RBL2 AHSG ABL1 ZC3H18 ELAVL1 BRAF CENPF RUNX1 BAG3 CIT ABI1 BRD2 MARK3 CRK UBAP2L MYCBP2 CLCC1 MEPCE POLA2 CRTC3 USP15 MARK2 CCDC86 GSK3B FRMD8 PLEC PLEKHA5 RPS6KB1 ARHGEF12 SGTA EIF4B SRGAP1 AUTS2 SLC4A4 YAP1 SH3RF1 COBLL1 PKP4 KIAA1217 MARCKS RPL24 ZEB1 CEP170 ARID5B NEDD4L SRRT TAGLN2 C2CD2L TMEM184B LSP1 RIPOR1 STMN1 TBC1D9B HS1BP3 NUMA1 CAD LMNA ZYX PLK1 TOP2A ARHGAP31 LMNB1 ARHGAP29 BUB1 CDC6 SMTN SLCO4A1 TPX2 ANLN NCAPH CDC20 UNC13B HJURP MKI67 DTL MLF1 AKAP12 LLGL2 FAM83H CDKN1A MYC ZFP36L1 CDYL EP400 MITF BCL9L CEP170B ZNF687 MAP2K3 BIN1 PTPRU MEF2A CCDC9 KMT2B KIF13B ZFAND3 PLEKHG3 ULK1 SMARCA1 AKT1S1 CHAF1B NCAPD2 PBK ARHGEF39 MASTL PHF11 ADAR TRAFD1 TNS1 SNRK PPP1CB PCBP1 JUNB PPP1R14A VIM CD97 ERRFI1 TNS3 FNDC3B RBM7 PHLDB2 NUCKS1 GEM SCML2 TNFAIP3 LCE3D FILIP1L PPFIA3 FOXK1 BRD1 FLRT3 IRF2BPL ACIN1 GPKOW RNASEH2A MBD4 NELFE TMPO NUP107 RRN3 PLEKHH2 NUFIP2 SAMD4A ID2 CLIP2 ATAD2 CDCA7 ABL2 ZC3HAV1 RGS10 DYNC1LI1 KATNA1 MAP1S PSIP1 MCM4 SLC20A1 ALYREF HAUS6 LMNB2 KIF3B CNNM3 REEP4 HERC1 PNISR THOC2 THRAP3 SRRM2 LIMA1 CDK17 BAZ1A PATL1 RHBDF2 OPTN KHDRBS1 NONO SON ADD3 NAV1 SOBP PDLIM2 STK17A ETV3 PUM1 TERF2IP RANBP2 CAMSAP1 NUP153 SEC16A SPP1 UVRAG PPHLN1 AHNAK CDC42SE1 MFF MCM9 PHC3 MTA2 EML4 DNTTIP2 MTA3 AKAP10 PTPN12 ZMYM2 HTT ARID1B AKAP13 PHLDB1 SYNM BAIAP2 NCOR2 PRRT3 KLC4 NBN SMAP2 TANC1 PRDM2 MYO9B RAPGEF1 LUZP1 KANK2 MICAL3 RAF1 ABR FLNC TSSC4 UCK2 DDX42 NAP1L4 MTUS1 HDAC4 ARHGAP5 ARID1A NCOR1 NCOA2 PARD3 JMJD1C RALGAPA2 NF1 EHMT2 TSC2 PCM1 ZBTB21 AMBRA1 PRR5 TP53BP1 DCAF1 SPHK2 UBR4 CNOT2 RFC1 ANKLE2 SCAF11 RALGAPB PARP4 NCOA1 SYNPO RBM17 AFDN ABI2 MTDH MGMT REPS1 ANAPC1 ZC3HC1 TCOF1 RRP1B PMS2 NOLC1 CDK12 MAGED2 SLC4A7 EIF4ENIF1 ATXN2L MGA RASAL2 EPS15L1 RPA1 AFAP1 PFKFB2 CPD TMEM131 DENND4C CLDN12 PHRF1 HCFC1 OSBPL10 TBC1D4 NCBP3 C1ORF131 CAMSAP2 RBM15 PHACTR2 CDK13 CLIP1 UCKL1 CCDC61 ZNF609 NEK1 PCF11 MORC2 PALLD DOCK5 HNRNPA3 CDK14 H1-2 FAM53A SEPTIN9 ATL3 LNPK DOCK7 KMT2D ZHX3 MPRIP ZC3H13 HNRNPU DBNL BAZ1B TRIP12 RBM25 TCF20 PRPF4B ZFC3H1 RASSF8 IRF2BP2 MICALL1 DPYSL5 FMNL3 HDGFL2 CXADR OSBPL11 LARP4 FRMD4A SNAP23 SRRM1 NKTR SORBS1 ZNF622 CHAMP1 ARHGAP39 SCAMP3 DBN1 STRIP1 CHTOP STK11IP ITPRID2 FAM53C WIZ PANK2 JPT2 SRBD1 REEP3 KLC2 SGTB ELFN2 BAG4 HABP4 ZNF638 CLASP2 ZNHIT2 JCAD SHROOM2 WDR91 BUD13 YRDC FAM122A PPP1R35 YEATS2 FBXO42 MVB12B PAK2 RIF1 SURF6 PLEKHG4 TBC1D1 WWC2 CLASP1 MAP7D3 CCDC8 DLG5 RSL1D1 LRCH3 CSDC2 CRYBG1 SLAIN2 CDC23 RANBP3 CBX8 ESS2 LCE3E TASOR2 ATRIP 541 proteins up-regualated at 24h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 24h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) MYH9 PTPN14 MPHOSPH10 HDAC2 ATP13A3 HSP90AB1 APC HECTD1 LARP1 SQSTM1 SPTAN1 PRKACA ITGB1 RRP9 MACF1 MIB1 EPB41L1 TOR1AIP1 PFKL RETREG3 PKM ANXA2 ING5 BRAF HSPB1 LARP7 MAPK14 FRMD6 SNIP1 GIGYF2 DNMT1 STAT1 MEPCE TRIM28 NUP214 RCC1 NPM1 PPIG NUP98 ZNF318 PRKAR2A EGFR GOLGB1 PPIA PLEC CHD1 SPTBN1 PLEKHA5 NAP1L1 SLC7A6OS TLN1 SF1 SAC3D1 CAV1 RPS20 MNAT1 NCOA5 EIF4B RPS17 PARD6B SLC4A4 RAI14 PATJ COBLL1 PKP4 RPL24 CYBRD1 FNBP1L TJP1 KIAA1671 KIAA1143 ZC3HAV1L RPLP1 SRRT KHSRP CD2BP2 SYMPK RMDN3 USF1 ZNF316 TBC1D9B LEMD2 NUMA1 RETREG2 LMNA TKT ACLY SYNGR2 TOP2A EZH2 SAP30 CYFIP1 SLC16A1 KCTD3 KIAA0930 ARHGAP29 FKBP5 STARD13 ITSN1 SH2D4A EIF4G1 GAPDH NME1 ARHGAP23 MKI67 SORT1 NCAPG ABCB1 MIB2 TNRC6C AKAP12 IWS1 CTNNA1 STK4 CDYL STK3 ABCF1 HMGA1 BCL9L USP32 KIAA1522 BCAS3 LSR HEATR6 ITPR3 SLC4A2 WDR37 MAP2K3 HNRNPH1 ARHGAP1 HNRNPH2 HERC2 PNN HNRNPK CTR9 SAFB PSMA3 PRKACG PACS1 RERE RGL2 SCAF1 OGFR LRCH4 INCENP TIMELESS DPYSL2 BMPR2 TUBA1B HMGN1 MYL12B EEF2 MYL12A PCBP1 RBMS1 SPECC1L LIMCH1 ALDH1A1 MYH10 NME2 PSMB5 HNRNPUL1 MATR3 CCT4 VIM PDCD4 DDX17 RNPS1 TNS3 PRPSAP1 FASN CFDP1 VPS35 RBM7 SRSF3 PDCL3 ZFP91 CDK11A NUCKS1 MYO18A VCL PGRMC1 PGLS RBM8A CBX3 SLC18A3 FOXK1 BRD1 BABAM1 ACIN1 WDR77 TMX1 TAF12 DDX18 TFPT CDC26 PPP1R18 HDAC1 DKC1 PCBD1 SSB NELFE SKP1 RPS6KA3 BZW1 AKR1B1 LEO1 USO1 RPL29 WBP11 MFAP1 RHPN2 VGF ZDHHC23 MAP1B SURF2 SETD2 KDM3B HDGF MTFR1L CLIP2 CDH6 CTDP1 SLIRP TRA2B TRIM5 RASL11A MAP1S MSI1 MTCL1 MCM4 WDHD1 LIG1 HNRNPA2B1 BCL10 NIPBL UTP20 KIF1A EIF5B PPP1R9A ATRX BOP1 REEP4 PRKACB GFPT1 BOD1L1 PPP1R10 THRAP3 RSF1 SRRM2 RBM34 RCAN1 ANP32B RHBDF2 N4BP1 SH3KBP1 MVB12A PYGL MYL9 HNRNPA1 SON PUM2 NEK6 DPYSL3 RUBCN PSMD11 RANBP2 OSTF1 USP14 EIF2AK4 CREB1 MDM4 DPP9 NFKB2 ARRB1 TXNL1 TOM1 DFFA SAE1 PRPF6 USP39 TNFAIP1 STK10 SZRD1 C9ORF78 CDC42BPB CCZ1B STK25 MPST ERCC5 MFF FIP1L1 DDX54 SUV39H2 MPHOSPH8 AHCTF1 KTN1 RBBP6 CEBPZ STT3B AKAP10 PTPN12 CPSF3 ZMYM2 RALY EEPD1 AKAP13 SYNE2 PHLDB1 POLR2A STK24 HNRNPC MADD RRP1 ARHGEF7 ZSCAN18 NOP56 LUZP1 MDC1 TTC7A KANK2 SRCAP MICAL3 DST XPC ABLIM3 KAT5 FLNC CTTN DDX42 PPP1R12A PSMD2 NAP1L4 XRCC6 PBRM1 ITGA3 HNF1B ADD1 PTK7 IGF2R SRF RREB1 ELAC2 SSRP1 CCAR2 TRIM24 MAST2 RALGAPA2 TNKS1BP1 DCLK1 RING1 RRAS2 SUZ12 SMC4 TRA2A ZBTB21 LRWD1 HSF1 RACK1 ATG2B TP53BP1 DCAF1 UBR5 UBR4 RABGAP1 BCL2L13 TUBGCP5 HUWE1 PSMF1 GIT2 TBC1D15 SLC4A1AP UBXN7 GBF1 RANBP1 PPM1B AKR7L PHF6 ACSS2 MAP3K2 PEA15 FUBP1 LIMK1 RBM17 NSD3 CDK11B BCLAF1 CCNH POLR3E CPSF2 SUDS3 PPIL4 RECQL4 BYSL CD2AP MAP2K4 CDK12 WDR70 VIRMA HSPA9 MAP2K2 MAP2K7 ARHGEF2 OXR1 NSFL1C FLNB POGZ GTF3C4 DPF2 MED1 DDX24 BRPF1 SPIRE1 KDM2A ARHGEF28 PACSIN3 TRIM47 RNPC3 CCDC6 PHIP IGF2BP2 HCFC1 HSPBP1 ARFGEF2 OSBPL10 DIDO1 CAMSAP2 RBM15 SVIL CDK13 C1ORF52 GPATCH8 TRIO ZFR C2CD3 PDE8A NEK1 PCF11 NMD3 ZBTB7A FRA10AC1 H2BC11 SEPTIN2 DOCK7 FBXL20 PHKA1 SUPT6H MPRIP CHD3 ZC3H13 PDCD5 HIRIP3 TTC28 KIF1C PID1 BAZ1B TRIP12 EIF5 SAFB2 TCF20 PLEKHA2 SF3B2 PRPF4B FNBP1 RBM12B SIN3A PRR14 MRPS16 SERBP1 GIT1 EFR3A DMWD NUP35 KIFAP3 SMG8 ZMYND8 BRD3 SRRM1 NKTR SORBS1 COIL PDS5B XPO4 METTL1 RNASEH1 DBN1 PUS1 GNL3L RAD50 VAMP4 UBAC1 DOCK9 UBE4B STK11IP TSC22D4 SH3BP5L SUGP1 BIVM ATN1 YLPM1 SMARCAD1 CCDC12 RBMX2 C2CD5 SHROOM2 CCZ1 POP1 BUD13 R3HDM1 RBM26 TRRAP PPP6R3 RBM15B GARS1 FAM160A2 GRIP1 OSBPL3 RIF1 HOMER3 SPIRE2 KBTBD11 RFFL TBC1D1 ZFYVE19 BAG2 USP6 WASHC2A WASHC2C DDX55 WDCP ZNF22 KDM2B TASOR ANP32D RANBP3 OXSR1 H4C1 NIBAN1 SMAP WDR55 TBC1D14 405 proteins down-regualated at 24h in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in 24h SARS-CoV-2-infected vs 0h mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) UHRF1 RB1 RBL1 CDK5RAP2 APC HECTD1 LARP1 EPB41L2 SUN2 NEK9 PTPN21 MAP7D1 LARP4B MACF1 AHSG ELAVL1 ANXA2 CENPF RUNX1 CIT BRD2 MARK3 ZDHHC5 UBAP2L MYCBP2 MEPCE POLA2 NPM1 CRTC3 NUP98 MARK2 CCDC86 GSK3B PLEC CDK2 CHD1 PTK2 PLEKHA5 ERC1 RPS6KB1 NSMCE4A NEO1 ALB SGTA EIF4B AUTS2 TRPS1 YAP1 SH3RF1 COBLL1 PKP4 PTPN13 RICTOR MARCKS RPL24 ZEB1 CEP170 NEDD4L SRRT C2CD2L TMEM184B RIPOR1 STMN1 TBC1D9B HS1BP3 NUMA1 FLNA LMNA ZYX PLK1 TOP2A LMNB1 DEPDC1B ARHGAP29 BUB1 CDC6 EIF4G1 SMTN SNAPIN SLCO4A1 TPX2 ANLN NCAPH CDC20 PKMYT1 HJURP MKI67 DTL AKAP12 FAM83H CDKN1A ZFP36L1 EP400 BCL9L PAK4 CEP170B ZNF687 MAP2K3 SAFB PRC1 PTPRU MEF2A FOSL2 KIF13B ZFAND3 PLEKHG3 ULK1 AKT1S1 CHAF1B ECT2 PBK ARHGEF39 MASTL ADAR TRAFD1 DPYSL2 EHD4 BMPR2 TNS1 SNRK PCBP1 JUNB POLDIP3 PPP1R14A VIM SP3 ERRFI1 MYLK TNS3 FNDC3B RBM7 VPS26A PHLDB2 NUCKS1 GEM SCML2 DGKQ TNFAIP3 LCE3D FILIP1L PPFIA3 FOXK1 MAPRE3 ACIN1 MBD4 DKC1 DONSON TMPO ANKRD39 NUP107 RRN3 PTBP3 PLEKHH2 NUFIP2 SAMD4A ID2 CLIP2 ATAD2 CSRP1 CDCA7 JPH1 TRA2B FAM110A ZC3HAV1 PIKFYVE RGS10 DYNC1LI1 AJUBA KATNA1 MAP1S PSIP1 MCM4 SLC20A1 ALYREF HAUS6 LMNB2 KIF3B SPAG9 KPNA6 MLF2 TWISTNB HERC1 PNISR THOC2 THRAP3 SRRM2 BAZ1A PATL1 RHBDF2 SEC61B KHDRBS1 AKAP11 NONO SON ADD3 SOBP STK17A ETV3 PUM1 UFD1 SSU72 RANBP2 UBE2J1 CAMSAP1 NADK MAP3K7 ATG9A SEC16A SPP1 WTIP C12ORF45 PPHLN1 AHNAK CDC42SE1 CCZ1B NDE1 MFF DDX54 MTA2 EML4 INPP5E MSH6 DNTTIP2 WDR43 AKAP10 HTT ARID1B AKAP13 PHLDB1 SYNM BAIAP2 NCOR2 ATP13A1 PRRT3 NBN STRN4 TANC1 RAPGEF1 MDC1 SMPD4 MICAL3 RAF1 ABR LRRFIP1 FLNC TSSC4 UCK2 NAB2 PBRM1 MTUS1 HDAC4 ARHGAP5 NCOR1 MAGI3 JMJD1C SIPA1L3 RALGAPA2 DCLK1 NF1 EHMT2 TSC2 PCM1 LRWD1 AMBRA1 TP53BP1 DCAF1 PRKDC CNOT2 RFC1 ANKLE2 SCAF11 RALGAPB PARP4 NCOA1 AFDN ABI2 MTDH MGMT REPS1 MET ANAPC1 UTP11 ZC3HC1 RCC2 TCOF1 RRP1B PMS2 CD2AP NOLC1 SNRPC SLC4A7 EIF4ENIF1 ATXN2L MED1 MGA GTPBP4 GPATCH2L MID1 RPA1 AFAP1 CPD TMEM131 DENND4C AEBP2 PHRF1 HCFC1 ZNF444 TBC1D4 NCBP3 RBM15 CDK13 CLIP1 CDK18 UCKL1 CCDC61 ZNF609 NEK1 PCF11 MORC2 PALLD BRWD1 CDK14 H1-2 RIPOR3 H1-3 FAM53A ATL3 LNPK DOCK7 KMT2D ZHX3 MPRIP ZC3H13 DBNL BAZ1B TRIP12 XRN2 RBM25 ZFC3H1 IRF2BP2 MICALL1 FMNL3 HDGFL2 CXADR LARP4 RAD18 TNS2 FRMD4A NUP35 SNAP23 SRRM1 SORBS1 RAB3IP ZNF622 SAV1 ARHGAP39 PDS5B CD3EAP DBN1 STRIP1 ZNRF2 ITPRID2 TFAP4 FAM53C WIZ PANK2 JPT2 SRBD1 FAM76B KLC2 SGTB BAG4 HABP4 ZNF638 CLASP2 ZNHIT2 WDR91 CCZ1 BUD13 YRDC FAM122A YEATS2 FBXO46 ARFGEF1 RIF1 SURF6 TEPSIN TBC1D1 MAP7D3 WASHC2A WASHC2C INTS10 RSL1D1 DCAF15 LRCH3 CRYBG1 SLAIN2 H2AX CDC23 BCLAF3 CBX8 LCE3E TASOR2 ATRIP MTMR2 235 proteins up-regualated in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in SARS-CoV-2-infected vs mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) MYH9 MPHOSPH10 HDAC2 ATP13A3 HSP90AB1 MACF1 RNF2 RETREG3 PKM BRAF HSPB1 LARP7 FRMD6 SNIP1 DNMT1 NUP214 RCC1 NPM1 PPIG PPIA PLEC CHD1 PLEKHA5 TLN1 SAC3D1 CYBRD1 FNBP1L TJP1 KIAA1143 CD2BP2 USF1 ZNF316 NUMA1 RETREG2 TKT WDR13 TOP2A EZH2 SAP30 SLC16A1 KIAA0930 STARD13 EIF4G1 SORT1 NCAPG AKAP12 IWS1 CTNNA1 STK4 STK3 ABCF1 HMGA1 HERC2 HNRNPK CTR9 SAFB PSMA3 SCAF1 OGFR TIMELESS DPYSL2 RPS28 EEF2 ALDH1A1 HNRNPUL1 MATR3 VPS35 PDCL3 NUCKS1 MYO18A VCL PGRMC1 RBM8A SLC18A3 BRD1 ACIN1 TAF12 DDX18 TFPT CDC26 HDAC1 DKC1 PCBD1 SSB SKP1 BZW1 LEO1 MFAP1 VGF ZDHHC23 MAP1B SURF2 SETD2 CDH6 SLIRP TRA2B MSI1 MCM4 MCM7 WDHD1 HNRNPA2B1 RPL22L1 UTP20 KIF1A EIF5B BOP1 THRAP3 RSF1 SRRM2 RBM34 RCAN1 RHBDF2 SH3KBP1 PYGL PUM2 DPYSL3 RANBP2 OSTF1 EIF2AK4 ARRB1 TXNL1 SAE1 PRPF6 USP39 TNFAIP1 STK10 C9ORF78 CCZ1B STK25 ERCC5 FIP1L1 DDX54 SUV39H2 CEBPZ AKAP10 CPSF3 ZMYM2 RALY EEPD1 SYNE2 STK24 MADD NOP56 MDC1 XPC KAT5 RRP7A NAP1L4 PTK7 IGF2R SRF RREB1 ELAC2 SSRP1 USP28 RALGAPA2 TNKS1BP1 DCLK1 RRAS2 SUZ12 ZBTB21 LRWD1 HSF1 ATG2B TP53BP1 PRKDC HUWE1 SLC4A1AP UBXN7 GBF1 PPM1B PHF6 MAP3K2 PEA15 RBM17 BCLAF1 CCNH POLR3E PPIL4 BYSL CD2AP CDK12 WDR70 VIRMA DPF2 DDX24 SPIRE1 KDM2A ARHGEF28 PACSIN3 PHIP RBM15 CDK13 GPATCH8 NMD3 BCKDHA ZBTB7A SEPTIN2 PHKA1 SUPT6H CHD3 PDCD5 HIRIP3 PID1 BAZ1B TRIP12 SF3B2 PRPF4B EFR3A SMG8 ZMYND8 SRRM1 PDS5B RNASEH1 UBAC1 UBE4B SUGP1 BIVM CCDC12 CCZ1 R3HDM1 PPP6R3 GARS1 FAM160A2 SPIRE2 WASHC2A WASHC2C DDX55 KDM2B ANP32D RANBP3 OXSR1 NIBAN1 WDR55 TBC1D14 238 proteins down-regualated in SARS-CoV-2 infected cells from Bouhaddou et al. 2020 Proteins differentially phosphorylated in SARS-CoV-2-infected vs mock-infected Vero E6 cells from Bouhaddou et al. (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (Cell, 8/6/2020) PTPN14 RB1 APC HECTD1 LARP1 EPB41L2 NEK9 MAP7D1 LARP4B MACF1 AHSG ZC3H18 ELAVL1 RUNX1 BAG3 CIT UBAP2L MYCBP2 MEPCE POLA2 NPM1 CRTC3 MARK2 CCDC86 GSK3B PLEC PLEKHA5 RPS6KB1 ARHGEF12 SGTA EIF4B AUTS2 SLC4A4 YAP1 PKP4 MARCKS ZEB1 CEP170 NEDD4L SRRT C2CD2L STMN1 TBC1D9B HS1BP3 LMNA ZYX PLK1 TOP2A LMNB1 BUB1 SMTN SLCO4A1 TPX2 ANLN NCAPH HJURP MKI67 DTL CDKN1A ZFP36L1 CDYL EP400 BCL9L CEP170B MAP2K3 PTPRU MEF2A KIF13B ZFAND3 PLEKHG3 ULK1 CHAF1B NCAPD2 PBK TRAFD1 BMPR2 TNS1 JUNB VIM TNS3 FNDC3B PHLDB2 NUCKS1 GEM TNFAIP3 PPFIA3 BRD1 ACIN1 TMPO ANKRD39 NUFIP2 ID2 CLIP2 CDCA7 ZC3HAV1 RGS10 DYNC1LI1 KATNA1 MAP1S PSIP1 SLC20A1 HAUS6 LMNB2 TWISTNB HERC1 PNISR THRAP3 SRRM2 BAZ1A RHBDF2 OPTN KHDRBS1 AKAP11 NONO SON ADD3 SOBP ETV3 PUM1 RANBP2 CAMSAP1 MAP3K7 NUP153 SEC16A SPP1 PPHLN1 AHNAK MTA2 EML4 DNTTIP2 ARID1B AKAP13 PHLDB1 SYNM NCOR2 PRRT3 SMAP2 MYO9B LUZP1 MICAL3 FLNC TSSC4 UCK2 NAP1L4 MTUS1 NCOR1 JMJD1C RALGAPA2 EHMT2 PCM1 AMBRA1 TP53BP1 DCAF1 CNOT2 ANKLE2 NCOA1 SYNPO RBM17 AFDN MTDH REPS1 ANAPC1 ZC3HC1 TCOF1 RRP1B PMS2 NOLC1 EIF4ENIF1 ATXN2L MGA RPA1 CPD TMEM131 DENND4C PHRF1 HCFC1 TBC1D4 RBM15 CDK13 CLIP1 UCKL1 ZNF609 NEK1 PCF11 PALLD H1-2 H1-3 FAM53A ATL3 LNPK DOCK7 ZC3H13 HNRNPU DBNL BAZ1B TRIP12 ZFC3H1 MICALL1 FMNL3 HDGFL2 OSBPL11 LARP4 FRMD4A SNAP23 SRRM1 NKTR DBN1 STRIP1 STK11IP ITPRID2 FAM53C WIZ PANK2 JPT2 KLC2 SGTB BAG4 HABP4 ZNF638 CLASP2 ZNHIT2 JCAD SHROOM2 WDR91 FAM122A YEATS2 MVB12B RIF1 SURF6 TBC1D1 CLASP1 MAP7D3 RSL1D1 LRCH3 CRYBG1 SLAIN2 CDC23 CBX8 50 genes involved in SARS-CoV-2 entry from genome-wide CRISPR screen of Zhu et al. A genome-wide barcoded CRISPR activation screen was performed to identify novel host factors that enable SARS-CoV-2 infection. Genes listed in Figure 2B with red shading (for any 1+ of the 4 screening groups) are included in this set. From Zhu et al. (2021) Genome-wide CRISPR activation screen identifies novel receptors for SARS-CoV-2 entry (bioRxiv, 4/09/2021) UHRF1 TMPRSS2 CTSL PRSS58 ACE2 GGT1 CLEC4G MXRA8 YME1L1 TMEM30A TMEM106A ALCAM EPHB1 B4GALT6 AXL TPP2 NPEPL1 CLEC5A USP18 AAK1 PRDX5 ICAM2 ATF4 SLC5A10 EGR2 CLDN6 LYPD1 CPLX1 CA9 PRTN3 MASP1 TRABD2B RAET1L TMPRSS15 TMPRSS9 GPM6B TFPI SLCO4C1 TCHP LMLN LDLRAD3 FAM109B P2RX1 DESI2 ATAD1 HMSD ARL6 STAMBPL1 OR10G7 ZMAT1 500 top upregulated genes from SARS-CoV-2 infection at 24 HPI from GSE157852 Bulk RNA-seq of human choroid plexus organoids (CPOs) was performed on mock 72 hours post-infection (hpi) and SARS-CoV-2 24 hpi samples. All conditions were profiled in triplicate. MYH9 F2RL1 ADAMTS1 ATP13A3 CCL2 LOX CAPN2 ITGB1 MME IL17RD TPM4 ANXA3 COL4A1 ANXA2 GTF2F2 ETV1 NEDD9 ADAM9 RUNX1 PMEPA1 KLF6 TUBA1A RYBP HMOX1 SERPINE1 FRMD6 PLS1 ANXA13 FN1 SLC5A12 PLS3 ANO6 FERMT2 HKDC1 UAP1 ARL14 PTK2 LRRC8A TMEM30A GBE1 CD55 OCIAD2 ENAH SRGAP1 DDAH1 RARB KLF5 TM4SF1 RBPMS HES1 EXT1 RAI14 SYTL2 LMO7 NFIB MYO5B RHOBTB3 OSMR PAWR SCIN GADD45A RND3 FNBP1L ANKRD33B PRSS23 S100A2 MBNL2 ARID5B AADAT STMN1 THBS1 HBEGF ITGA5 NRP2 MYOF CDKN3 GLRX MYO1E KCTD3 DEPDC1B DDIT4 RBBP8 ELL2 ALCAM PDGFC RNASE1 GPNMB HGF IL18 SLFN11 NME1 CDKN2B DPYD ARNTL2 NRIP1 SLC43A3 AKAP12 IGFBP3 NUAK1 STAM MYC RUNX2 KLF10 ABCC5 COL1A1 ZFP36L2 GADD45B AXL AMTN EDN1 PLAUR GAD1 TMOD3 GPR87 COL17A1 FAM84B EPPK1 SLC7A1 TMSB4X FGF1 STMN2 ODAM ATF3 F2R SOX11 RYK PTHLH FOSL2 NUAK2 TNFRSF9 PARPBP CCL20 TOX GLIPR1 COTL1 TMEM45B CD274 GRIA1 PTAFR VCAN DIO2 TNFRSF12A GLIPR2 GCH1 ADM NFIL3 SERPINA3 LIPG PPA1 PLAU FST CTHRC1 AHR EHD4 CLIC4 ETS1 CYR61 IER3 SGK1 MYL12B HMGCS1 TMCC3 MYL12A KLHL5 UBL3 GBP3 JUN SEMA3C CTGF DRAM1 H2AFZ PDE5A ACAT2 TAGLN S100A6 PTP4A2 CCKAR ARRDC3 VIM ERRFI1 MYLK FNDC3B ANXA1 PHLDA1 PHLDB2 RFTN1 RAB3GAP1 RGS5 PICALM SEC61G VCL S100A10 BNIP3L GEM CREB5 RGS4 TRIM22 DCUN1D3 KBTBD8 TNFAIP3 ZNF267 CDH18 HERC3 FAM150A AMOTL2 DUSP6 LIF DUSP5 CSRNP1 MIR155HG MIR21 ZSWIM6 BHLHE40 TSC22D2 IL11 ATP6V1C1 S100A11 LINC00152 VMP1 CORO1C GNG12 HSD17B2 SUSD5 GJA1 BZW1 FAM122B XPR1 KLF7 ANKRD1 NEAT1 ANKRD45 ENC1 SAMD4A NOA1 RNF19A HIVEP2 COL11A1 C3ORF52 CD46 CSRP1 ITGAV CD47 ME2 ABL2 PCGF5 AJUBA HS3ST3A1 CYP1B1 CTSV PELI2 BBOX1 IL32 HIST1H2BG GPR63 DIRAS3 AHNAK2 CAB39 GBP1 CRIM1 LAMC2 FEM1C EMP1 FAM110C LIMA1 HPS5 WEE1 AFF4 RCAN1 OXTR IRS1 PHACTR4 PANK1 SERPINA1 ACTN1 MYL6 RAB31 RAP2B ARHGEF3 CD44 NAV1 ACTA2 MIR17HG LEMD1 IL1RAP BACH2 CLK1 FHL2 SERPINB8 MIR4435-1HG SLC25A32 NT5DC3 ADAM19 SLC26A7 SPOCD1 CALD1 ACTG2 SPRY4 LINC00707 CD68 ETV3 CCL7 SFR1 GNAQ TIMP3 CA12 F2RL2 PELI1 NEDD4 COPG2 CYLD PPP4R1 TPM1 PCDH11Y ARL8B ADTRP DCAF13 LRRC20 PTP4A1 SOCS6 DHX29 CDCP1 KIAA1024 ATXN1 PPP1R3B ACSL1 SSH2 ELK3 SSH1 DST BAALC NES ITGA3 SGPL1 WASL FAM91A1 CPA4 INSIG2 STK38L E2F3 FOXP1 WWTR1 LPP DCLK1 GCNT1 CDH11 PDGFB CCNG2 SYNJ2 TMEM144 RBPJ EVA1A DDIT4L FBXO32 SLC19A2 IL13RA1 SEC24A GPR137B UGCG GCSAM SOX4 MET PPIL4 LAPTM4B PRDX6 XIRP1 FLNB PTRF SEL1L3 SLC4A7 SH3RF2 LETM2 FNDC3A SKIL NRCAM HIVEP1 AIF1L DSEL COL8A1 KCTD11 LTBP2 KLHL4 PCDH7 LRRC8C TES NABP1 HSPA13 IFRD1 PPFIBP1 SERTAD4 IDS RASA2 MAP4K5 SNHG3 PIP4K2A PALLD RAPGEF6 PRKAB2 GJC1 FRYL ARAP2 OXCT1 PRKCB DGKA CAP2 OTUD3 TM4SF18 BTBD10 TBC1D23 TSPAN2 RABGGTB ITPR2 KDM7A SPECC1 ERO1L N S RNF217 ORF7A ORF3A RDH10 GABRA2 TMEM158 INA PGM2L1 MIR100HG SNORD80 IL8 PALM2 NUPL1 RP11-10A14.5 VIM-AS1 GALNT13 LOC151760 ANO4 ASUN KIAA0020 FSTL5 EDARADD CHN1 PAK2 CTTNBP2NL THADA IL1RAPL1 TMC7 SLC30A10 LRCH2 MEST ASPN KLHL20 NFASC RPSAP52 GMNC KIAA0355 LINC01111 SFTA1P LINC00968 PTPLA LOC730268 ADAMTS9-AS2 MIR7-1 EFCAB5 FBXL2 RP11-319E12.1 LDLRAD4 ORF6 LOC102723331 ORF1AB/ORF1A LOC101927385 LINC01164 LOC101927260 E LOC101929500 ORF8 FAM13A-AS1 RPL23AP64 CASC15 CNTN2 ORF7B EDIL3 RP11-600K15.1 FAM221A LOC101929398 PABPC5 COPG2IT1 LOC101929959 LOC101927957 POU2F3 BANCR LOC102724598 GABRG2 KCTD4 KIAA0922 M ORF10 OPA1-AS1 ZNF702P RP11-245M24.1 SNORD79 RALYL LOC101929555 500 top downregulated genes from SARS-CoV-2 infection at 24 HPI from GSE157852 Bulk RNA-seq of human choroid plexus organoids (CPOs) was performed on mock 72 hours post-infection (hpi) and SARS-CoV-2 24 hpi samples. All conditions were profiled in triplicate. RTN4 IDE CDK5RAP2 TMEM37 VCAM1 TUBGCP3 SEPP1 CRYL1 TUBB4B JAK2 F5 USP2 FABP6 VSTM4 NCKAP5 ITM2A KCNJ13 AAR2 EPHX2 MAPK1 RAB11FIP2 ADHFE1 FARS2 KDR CISD1 ARHGAP18 METTL7A GPR155 IFT122 RNF167 TMEM86A ELL3 SERPING1 SNTN DANCR TMC5 STOX1 LMO3 DNALI1 IL5RA SLC15A2 A2ML1 REPS2 SLC40A1 SOX2-OT FGFR2 THRB LRRC18 ZNF204P PPIL6 COBLL1 CNTN5 MAP3K19 FREM2 GALNT5 RPL13A C4ORF19 FMN1 NDRG2 FAM183A EYA1 C2ORF73 MEIS1 TC2N SYBU DDOST LGALS3BP PROS1 PLOD1 CPVL FLVCR2 PLBD1 HSD17B4 NEK2 HVCN1 NDUFS7 BUB1B SLC39A11 MERTK IDH1 TEX2 ACO2 ALDH9A1 GSTM2 PER3 GDF11 CDHR3 LIM2 CDHR1 SLC24A4 SERPINF1 ABCD2 LRP2BP SCN11A PAK4 CDH3 WIF1 HORMAD2 PRICKLE1 RAB4A LMX1A GMPS NUCB2 CNGB1 OCA2 GPM6A MAP2K6 CTSC SLC24A2 TBL1X COLEC12 RSAD2 CAMK4 MMS22L SLC29A3 SLC7A8 CMPK2 FSTL4 HERC6 CLDN2 SAMHD1 SLC4A5 GLT8D2 EPHX1 ATP13A4 DGKB ATP2B2 AARD PLTP SMDT1 ATP5G3 HPGD CLDN5 CA2 FABP5 TMEM50B RPL18A SEPW1 TRMT112 PSAP MPC2 CSF2RA RASSF5 NDUFC2 IGFBP5 COX14 HIGD2A RGS22 CAPSL ADAMTS17 EMX2OS PLCL1 ASXL3 SLC5A5 C21ORF128 ABCA4 ESRRG COL21A1 PPAP2B DRC1 CPXM2 INSR SLC25A27 EMX2 ATRAID DEPDC7 NQO1 PTRHD1 AIFM1 C12ORF10 TMEM14A HRSP12 HMGN3 LAMB1 ETFB FOLR1 TOB2 FAM117A SOSTDC1 MRPS6 PPM1H TACR3 RRAGB ID2 FAM129A BCHE OTX2 CDCA7 LINGO1 PIGT TMEM27 HS6ST3 STRA6 ADAMTS6 TDRD7 ANKFY1 FAM161A DDO ZMYND10 FAM92B SLC13A4 IFI6 GABRA3 DDX60 ABAT PLEKHA6 GALNT12 NPR2 LINC00276 LINGO2 NPY1R ZBED5-AS1 C1S RABGAP1L BTN3A2 BLNK BTC PIK3AP1 PTGS1 SERPINB1 S1PR1 CCDC178 CUX2 SKIDA1 BMF CACNB2 CACNA2D3 CHKA AIM2 SLC39A12 ADAMTS9 WFIKKN2 RSPH1 TMEM72 WSCD2 CLDN19 CASQ1 GABRR1 CRHR2 MASP1 TRIM32 SDHA ANAPC11 SYS1 EXOSC10 COQ9 NAAA BSG PPARGC1A TXN2 COQ4 NNT DCUN1D2 ACAT1 NELL2 GPR1 MANSC1 EPHA4 PARM1 RCBTB2 PLA2G4A CPS1 IPO13 AKAP13 P4HTM MPC1 MSI2 TAOK3 PARVB CRY2 ITPR1 SMARCA2 PPARA DGKG SLC13A3 SLC5A3 GNB3 ACVR1C SLC22A8 SEMA4G ECEL1 CALN1 EYA2 EPB41L4B STPG1 SATB2 USH2A ARR3 KAT2A CYP27A1 CPQ PRDM16 KCNA5 FGD4 ENPP1 SPTLC3 SLC5A6 GCLM OSBP2 GSTM4 UGT2A1 SLC23A2 PPP1R1B SPAG8 SHC3 TMEM59 ETFDH AK1 HNMT PNKD ACSF2 C22ORF23 MAGED2 ATP5B LOC100294145 ELP6 PRELID2 SEMA6D DZIP3 SRGAP3 NHLRC3 GPD1L TECR WRAP53 TSEN2 UCKL1 DHRS3 CCDC167 ECH1 PDE8A DNMBP SUGP2 SLC20A2 SLC41A1 MED12L PRR14L GBA2 IQCK APPL2 TMCO3 PRLR PECR ATP11C AMT FCHSD2 GRHL1 FRAS1 MRPS18A PTPRN2 UBXN11 ATP8A1 FAM126A PGM5 RAB3IP FAXDC2 SLC25A12 C14ORF142 ADCK1 PRKCQ TMEM106C LDB2 ATP1A2 LINC00880 HIF3A COLQ EXOC6 LMBRD1 IFI27L1 KIAA1644 PLCH1 SLC35B4 AGL SERTM1 GPR85 C1QL3 UG0898H09 OPCML RAPGEF5 ST18 N6AMT1 UBXN10 LOC158960 MINA PCDP1 SLC22A17 GALT PRDM11 GPC6 RNF157 WDR91 SLC17A8 CCDC141 MVB12B LPAR4 CLUL1 KIAA1328 KCNB1 TBC1D1 NSUN7 IGDCC3 NWD1 ANKRD44 GRB14 SNED1 PACRG ADAMTS18 C14ORF159 SNCAIP FAM184A DHRS7B PDZRN4 FAM184A DHRS7B PDZRN4 EFR3B TMEM198B PHYHD1 KCNE2 TTLL9 HDC DYNC1I1 MAATS1 VWA3A C22ORF15 AIFM3 SNX29 CACNA2D4 CCDC40 LRRTM4 TEKT1 LOC149950 CCDC28B WDR65 OTX2-AS1 FAM19A1 TBC1D31 LOC100506127 CCDC148 CA14 LOC101927249 SNTG1 TTC18 ZNF684 LECT1 CCDC33 DPY19L2 FAM41C EFCAB1 C1ORF192 LOC102723673 IQCH-AS1 LINC00305 PIFO LOC728769 LOC100996521 NFYC EFHC2 KIAA1456 AKR1CL1 LOC101927234 SOX9-AS1 DNAH3 PRKCQ-AS1 FAM196A PLK1S1 NUDT19 RP11-48F14.1 TEKT2 SEPN1 LOC101928817 GRIK1 LOC101927760 DFNB31 NME9 LOC101929130 FAM138E C5ORF49 LINC00486 NIM1K TDRD3 WDR16 LRIT2 CCDC147 WDR96 RP11-231I16.1 RAMP2-AS1 SLC4A10 LINC00458 RP11-279F6.1 C12ORF55 LRRC37A6P LINC01171 LOC101927121 DNAH11 IQCG LOC101927532 VRK3 LOC101929882 RP11-389K14.3 WDR93 RP11-466A17.1 KATNAL2 C8ORF22 500 top upregulated genes from SARS-CoV-2 infection at 72 HPI from GSE157852 Bulk RNA-seq of human choroid plexus organoids (CPOs) was performed on mock 72 hours post-infection (hpi) and SARS-CoV-2 72 hpi samples. All conditions were profiled in triplicate. MYH9 F2RL1 ADAMTS1 UHRF1 CCL2 NOX4 EGR1 CAPN2 ITGB1 KPNA2 NOL10 TPM4 ANXA3 YWHAB TPM3 COL4A1 ANXA2 GTF2F2 NEDD9 ADAM9 RUNX1 ETV4 PMEPA1 KLF6 TUBA1A SERPINE1 FRMD6 PLS1 TUBA1C ANXA13 FN1 TUBA4A NUTF2 MFGE8 FBN2 MSN SLC5A12 YWHAH FERMT2 HKDC1 UAP1 ARL14 PTK2 FAH PCSK7 LRRC8A TMEM30A MCL1 OCIAD2 PARVA ENAH SRGAP1 DDAH1 RARB KLF5 TM4SF1 HES1 NT5E RAI14 SYTL2 METTL7B NFIB MYO5B OSMR PAWR CCDC80 SCIN FZD6 GADD45A RND3 ANKRD33B PTN ADAM28 PRSS23 S100A2 ABCA1 EHF ARID5B AADAT MDM2 THBS1 STEAP3 HBEGF GART ITGA5 NRP2 ZYX CDKN3 GLRX MGST1 RBBP8 ANXA5 CDC6 LAMC1 IL18 APOL4 NME1 CDKN2B DPYD ARNTL2 SLC43A3 A2M AKAP12 IGFBP3 NUAK1 STAM KLF10 COL5A2 ABCC5 COL1A1 MMP1 GADD45B AXL AMTN ACTB EDN1 PLAUR TMOD3 GPR87 COL17A1 DSP FAM84B EPPK1 FGF5 SFRP4 FGF1 ODAM ATF3 F2R DKK2 PTHLH TPBG FOSL2 SPDL1 AOAH BRIP1 CCL20 GPR176 ZWILCH GLIPR1 COTL1 CD274 GINS1 ALDH1B1 VCAN SOCS3 DIO2 TNFRSF12A GLIPR2 GCH1 SERPINA3 INHBA KLHDC8A PPA1 PLAU FST WARS MAMDC2 CTHRC1 AHR CLIC4 ETS1 PSME2 PFN1 CYR61 IER3 TUBA1B ACTG1 SGK1 MYL12B ELOVL5 TMCC3 MYL12A TXN ICAM1 ST5 GBP3 JUN SEMA3C CTGF DRAM1 H2AFZ EFEMP1 ACAT2 TAGLN ARPC2 S100A6 TUBB SH3BGRL3 CCKAR VIM S100A16 ERRFI1 ALOX5AP MYLK FNDC3B FSTL1 ANXA1 PHLDA1 ELOVL1 PHLDB2 RFTN1 RAB3GAP1 RGS5 VCL S100A10 GEM RGS4 EDN2 TRIM22 C8ORF46 BMP5 KBTBD8 SOCS2 EDNRA ZNF35 CDH18 NPPB AMOTL2 DUSP6 DUSP5 CSRNP1 MIR21 ZSWIM6 TSC22D2 PDLIM1 HMGB3 S100A11 GALNT7 EBNA1BP2 LINC00152 VMP1 CORO1C GNG12 TBC1D19 HSD17B2 SUSD5 CDC7 CAP1 BZW1 TUBB6 TMSB10 E2F7 KLF7 ANKRD1 NEAT1 ANKRD45 ENC1 RNF19A NTF3 C3ORF52 CDH6 CSRP1 ME2 SERTAD4-AS1 VAMP5 AJUBA ACTN4 HS3ST3A1 CYP1B1 BFSP1 CTSV IARS BBOX1 IL32 TTF2 FAM111B LOXL1-AS1 DIRAS3 AHNAK2 MIR22HG TRANK1 GBP1 PMCH UTP20 CRIM1 ACOT7 LAMC2 EMP1 RFWD3 LIMA1 WEE1 RCAN1 PMAIP1 OXTR PROCR IRS1 FAS C8ORF4 SERPINA1 RSU1 ACTN1 MYL6 RAB31 CASP8 ITK ACTR2 ARHGEF3 CD44 NAV1 ACTA2 CALB1 PDLIM3 LEMD1 IL1RAP BACH2 FHL2 SERPINB8 MIR4435-1HG NT5DC3 ITGB3 ITGB6 ADAM19 TUBB3 ADAM12 SLC26A7 ROR1 SPOCD1 CALD1 ACTG2 SPRY4 CADPS LINC00707 TGFB3 CDH2 CCL7 GLRX3 MAP4K4 TIMP3 CA12 F2RL2 NEDD4 GBA FARSB ARPC5 TNFAIP1 TPM1 BLOC1S2 ADTRP DCAF13 PDP1 DHX29 LLPH CDCP1 KIAA1024 PPP1R3B DAPP1 SSH2 ELK3 AMOTL1 FARP1 CTPS1 SSH1 BAALC NES HIPK2 ITGA3 SGPL1 WDR1 MMP7 STK38L E2F3 FOXP1 WWTR1 LPP MPHOSPH6 DCLK1 GCNT1 OPRK1 CNTNAP2 SYNJ2 GRPR EVA1A DDIT4L FBXO32 IL13RA1 HTR2A TDO2 S100B TGIF1 SULT1C4 TNC GCSAM SOX4 MET NUDT15 GPN1 MRTO4 FLNB PTRF SEL1L3 SH3RF2 SKIL NRCAM HIVEP1 MIR31HG DSEL COL8A1 LTBP2 KLHL4 PCDH7 FAM198B TES KIF5C NABP1 VASH2 SERTAD4 IDS GPATCH4 SNHG3 C2CD3 SLC35F6 PIP4K2A SNRPD1 HECW2 PALLD EEF1E1 NOP16 ARAP2 OXCT1 EIF6 ACOX2 DGKA PPME1 CAP2 TM4SF18 BTBD10 RBP1 PPP2R1B CDKN2B-AS1 ENTPD7 DFNA5 ITPR2 RNASEH1 ST7 BLM BLACAT1 WDR61 N S ORF7A ORF3A RDH10 TMEM158 PGM2L1 MIR100HG MAPK1IP1L PALM2 RP11-10A14.5 VIM-AS1 ARSJ LOC151760 GAP43 TTC27 KIAA0020 KCNQ5 CTTNBP2NL THADA IL1RAPL1 NPTXR ALPK2 ST8SIA3 ASPN KLHL20 SYTL4 NFASC RPSAP52 LOC100129940 GMNC MFAP5 SFTA1P LINC00968 EFCAB5 FBXL2 RP11-319E12.1 LDLRAD4 ORF6 LOC102723331 ORF1AB/ORF1A LINC01164 E ORF8 ORF7B LOC101927957 BANCR LOC102724598 KCTD4 M ORF10 RP11-245M24.1 LOC101929555 CLEC19A LOC102723744 LOC100506621 RBFOX1 RIMS2 STAMBP PCNXL2 FLJ35282 JAKMIP2-AS1 500 top downregulated genes from SARS-CoV-2 infection at 72 HPI from GSE157852 Bulk RNA-seq of human choroid plexus organoids (CPOs) was performed on mock 72 hours post-infection (hpi) and SARS-CoV-2 72 hpi samples. All conditions were profiled in triplicate. RTN4 ERMP1 CPA2 SEPP1 LYN CRYL1 COL4A3 JAK2 SLC46A3 USP2 MARK3 FABP6 NCKAP5 NR3C2 GIPC2 ITM2A KCNJ13 EPHX2 RAB11FIP2 GPHN ADHFE1 FARS2 KDR METTL7A ALDH6A1 FZD5 CACNB4 GPR155 ASB9 ELL3 SERPING1 DANCR STOX1 LMO3 IL5RA SLC15A2 A2ML1 REPS2 SLC40A1 SOX2-OT FAM216B FGFR2 THRB LRRC18 SLC4A4 ZNF204P COBLL1 KIF21A MAP3K19 FREM2 GALNT5 RPL13A LINC00632 SATB1 DYNLRB2 SSBP2 MORN5 EYA1 C2ORF73 PRNP ENPP4 KSR1 ACSS1 PROS1 GAS2L3 HSD17B4 HVCN1 ANO5 BUB1B NUDT16 MERTK IDH1 GSTM2 ENPP5 FAM160A1 LINC-PINT GDF11 CDKN1C LIM2 CDHR1 ZNF540 TGFBR3 FAM83H-AS1 GLYATL1 SLC24A4 SERPINF1 LRP2BP SCN11A CDH3 HORMAD2 RAB4A NUCB2 CNGB1 TYRP1 OCA2 GPM6A SORL1 TBL1X COLEC12 RSAD2 CAMK4 MMS22L IFIT1 PTPRC KCNA1 VAT1L CTSK CMPK2 HERC6 NRN1 CLDN2 SLC4A5 EPHX1 DGKB ATP2B2 SVOPL UQCRB HPGD ITM2B TSPAN7 CLDN5 CA2 DCN LUC7L3 TMEM50B NPR3 IFI30 PSAP AQP1 FAM107A MPC2 IGFBP5 ACADSB COX14 RGS22 C1ORF194 CAPSL EMX2OS PLCL1 ASXL3 SLC5A5 FAM167A ABCA4 C6ORF58 ESRRG COL21A1 PPAP2B SPOCK1 CPXM2 LINC00982 INSR TTR GNA14 STC1 RGS9BP ACTG1P4 SLC25A27 AQP4 EMX2 WRB DNER TMEM14A HRSP12 HMGN3 LAMB1 SCG5 PPP1CC FOLR1 TMEM245 AGPAT9 ATP2C1 SOSTDC1 SERINC5 FAM13A TACR3 ID2 KLHL24 PTPRD PHYHIPL LPPR5 CDCA7 JPH1 RDM1 TMEM27 HS6ST3 ROR2 TDRD7 DGAT2 SLC13A4 IFI6 SEC14L5 GABRA3 CCDC28A GMCL1 PLEKHA6 GALNT12 NEB STARD4 NPR2 CCDC42B LINGO2 AGBL2 HLA-DRA NPY1R LETMD1 ZBED5-AS1 ANP32B BTN3A1 C1S RABGAP1L BLNK SERF2 PTGS1 S1PR1 SRSF5 ADD3 CCDC178 SKIDA1 SIX3-AS1 CACNA2D3 SERPIND1 ENTPD1 DGKE AIM2 SLC39A12 LOC102467073 WFIKKN2 TRPM3 RNF144A WSCD2 CLDN19 C1ORF145 PCP4 GABRR1 CRHR2 MASP1 NAAA KIT SOX5 MLLT3 PPARGC1A PI4K2B SLC35F5 DCUN1D2 ANXA4 NELL2 GPR1 ST3GAL5 PARM1 LY75 RCBTB2 KCNS3 PTER ANKEF1 PLA2G4A KCTD6 CPS1 ADI1 MPC1 TPP1 ITPR1 OCLN SMARCA2 NPL PPARA DGKG SLC5A3 ACVR1C SLC26A3 SLC22A8 SPZ1 SEMA4G TRPM7 ECEL1 TEX15 CALN1 EPB41L4B SLC2A12 TIGD4 SATB2 USH2A COL10A1 ARR3 KCNA5 SESN3 FGD4 PLD1 ENPP1 ABCA5 GPC3 SPTLC3 SLC5A6 GCLM EDA UGT2A1 SLC23A2 PPP1R1B SPAG8 DOCK8 TMEM59 PALMD HSD17B12 TANC2 LOC100294145 CSGALNACT1 PRELID2 SEMA6D RNPC3 CPE C11ORF54 C9ORF72 DMXL2 DHRS3 PDE8A DNMBP SLC20A2 SLC41A1 DIRAS2 TTLL7 SCAI PRRG4 CPEB3 PPP4R4 MED12L DENND4A APPL2 TMCO3 PAIP2B NUDT7 UPP2 ATP11C FCHSD2 GRHL1 NID2 ADCY9 SFMBT2 ATP8A1 ATP13A5 NDNF LOC100131257 RAB3IP NHLRC2 MAP2K5 MTRF1L TMEM170A SLC25A12 C14ORF142 DOCK9 MPP1 RORA PRKCQ AFF1 LDB2 ATP1A2 KLHL3 LINC00880 HIF3A COLQ MOB1B SCML1 EXOC6 LMBRD1 SLC44A1 KIAA1377 CTAGE5 TMEM161B-AS1 CDKL2 AGL SLC18B1 SERTM1 GPR85 LOC101928704 OPCML RAPGEF5 ZNF483 SPATA6L GPC6 ARHGAP20 ACSL6 WDR91 FAM227A SLC17A8 TMEM116 CCDC141 AMY2B CLUL1 DENND2C ADAMTSL3 ARMCX4 CKMT1A NSUN7 IGDCC3 ADGB CALML4 KLHL31 NWD1 ANKRD44 FBP2 MFSD4 SNED1 PACRG ADAMTS18 ZFYVE16 SNCAIP N4BP2L1 FAM184A TRPM1 PDZRN4 FAM184A TRPM1 PDZRN4 NAPB KCNE2 TTLL9 HDC PEX11A GOLGA6L9 VWA3A CACNA2D4 FAM180A LRRTM4 OTX2-AS1 FAM19A1 TBC1D31 LOC100506127 CCDC148 CA14 LOC101927249 SNTG1 TTC18 LECT1 DPY19L2 FAM41C EFCAB1 C1ORF192 IQCH-AS1 LINC00305 PIFO LOC728769 LOC100996521 EFHC2 KIAA1456 AKR1CL1 LOC101927234 SOX9-AS1 PRKCQ-AS1 PLK1S1 NUDT19 LOC101928817 GRIK1 LOC101927760 DFNB31 FAM138E LINC00486 NIM1K TDRD3 WDR16 LRIT2 WDR96 SLC4A10 C12ORF55 DNAH11 LOC101927532 KATNAL2 PLAG1 LRRN2 RP11-276H19.1 LINC00894 LOC102724731 CCSAP C2ORF91 ZNF252P-AS1 RP1-104O17.1 STEAP1B TTC23L LOC101927086 RP11-436I24.1 LOC102724353 PRND SPAG6 LOC101927300 NR2F2-AS1 PVALB SNAP25-AS1 C6ORF118 EDNRB-AS1 RP11-637A17.2 LOC101928854 PLA2G1B ATP2B3 LOC729658 LRRC16A BRS3 HCG14 C9ORF117 GRIA3 DICER1-AS1 NEK5 FAM81B LOC644936 TPTE2P3 RP11-31F15.2 LINC01088 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GLA FCGRT MVP ABCC1 STAT3 TMPRSS2 NMI KPNB1 PCK2 DDX58 CXCL10 RIPK1 RNF24 CCND3 SLC7A7 ACAD9 LYN CUL1 CDHR5 LAP3 JAK2 MPZL1 RAB8A ANXA11 HMOX1 RBCK1 OAS1 FCGR2A MYO7B ST3GAL4 STAT1 TRIM25 IFITM2 TLE1 EIF2AK2 TMEM173 POR APOBEC3G OASL PXN MOV10 ISG15 IL17RA MARK2 LILRB1 MX1 MYD88 CHD1 RILP ARHGAP18 ACO1 RPS6KA5 ELL3 SERPING1 IFI27 FAM216B IGSF6 UPK1B MARCKS APOBEC3A CCL8 ISG20 ABCA1 DHRS9 PLA2G15 ITPK1 UNC93B1 ITGB2 PARP10 LGALS3BP TOR1B UQCRC1 RNASEL PARVG ARHGEF10L TOR3A GSN PTK2B TYMP BST2 B3GNT7 PLOD1 SLC16A3 EHBP1L1 HK1 ITGAM APOL2 ITGA5 GRN WDR13 HK3 SLC6A6 FBXO6 SLC11A1 MYOF MILR1 LMO2 C3AR1 NAIP PLBD1 SCARB2 GLRX IFI44 STAC3 NUDT16 GPNMB IRF5 SIGLEC11 MAFB CD163 SCIMP KPTN EPSTI1 ROGDI GALK1 BATF2 SPATS2L SPTLC2 CXCR2 IL18RAP GADD45B MPEG1 B3GNT9 TMC4 INPP5D ATF3 IRF8 ELF4 CTSC FCN1 NBEAL2 AP5B1 TNK2 ACPP TNFRSF1A NPEPL1 HELZ2 OGFR SGSH RSAD2 OAS3 IDO1 IRF7 NLRC5 SIRPB1 TAP1 C14ORF80 SLC29A3 GPR84 DEF6 IFIT1 FAM26F VAV1 FCGR2B RETN IFIT3 RTP4 OAS2 PHF11 SIGLEC1 XAF1 PSMB8 CD274 APOL6 CCR1 DHX58 IL1RN TREX1 USP18 CMPK2 IFIT2 IFI16 PLAC8 CD177 HERC6 IFIH1 STAT2 PML TCIRG1 ADAR GBP2 PARP9 PARP12 SAMD9L HSH2D TMEM171 GBP6 CASP4 AIM1 IFI35 PARP14 SOCS1 TRIM6 TRAFD1 SAMHD1 HAS1 UBE2L6 WARS SP110 IRF2 EHD4 SHISA5 IER2 LY6E IRF1 DTX3L IRF9 PSMB9 GBP3 ITM2C IFI44L NUPR1 TAPBP DDX3X ICAM2 CA4 GIMAP4 CD97 EHD1 FNDC3B HCK NCF4 KIAA1462 CD164 CLEC2B IL27 C16ORF86 CSF1 TRIM22 PGLYRP1 CYTH4 PLA2G4C PPFIA3 PAPD7 CSRNP1 ZNFX1 CHMP5 ATP6V0D1 LSM2 PSMB3 DYNLT1 FLOT2 SDC2 SMARCA5 PRPF3 PNPT1 MAD2L2 RPS6KC1 APOBEC3C SAMD4A TRAPPC12 RIPK3 FAM129A MMP9 GLCE GNB4 ME2 ODF3B TAP2 P2RY14 TNFSF8 SLFN5 TLR2 CASP1 PPM1K IL15RA ZCCHC2 CSF3R ETV6 LGALS8 MB21D1 TRIM21 RNF31 MOCOS GSDMD TAPBPL USP25 TRIM56 FAM46A ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 PCGF5 CCRL2 ANKFY1 C7ORF49 BATF3 FES FPR1 PRKD2 IFI6 DCPS DDX60 APOBEC3B LIG1 RNF19B C19ORF66 TNFSF13B XRN1 SP100 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 SAMD9 GBP1 CKAP4 CORO2A FMNL2 KLHDC7B CDK17 SIDT1 ETV7 MICB BAZ1A TICAM1 PATL1 NAPA SP140L RHBDF2 N4BP1 SMCHD1 WHAMM TMEM62 SOD2 MOB3C TRIM38 FAS PIK3AP1 TRIM26 SERPINA1 FCGR3B PTPN6 RNASET2 SERPINB1 SRSF11 PLEK ARMCX1 P2RY6 ACTA2 IL1RAP OSGIN1 EID3 SDC3 PLSCR1 CD68 PPM1J IFNGR1 SEMA4D EXOSC7 TANK FUT7 NAGK SIGLEC5 ARHGAP9 STX11 SCO2 NADK C19ORF38 SIGLEC14 CASP5 TNFRSF1B FAM111A SYK ERP29 GBA PRKAB1 UGP2 PDCD1LG2 BAK1 SQRDL PI4K2B LRRK1 KCNJ15 CITED2 ALDH3A2 CSRP2 TINF2 CTNNBL1 FFAR2 RIN2 HIRA KCNJ2 PON2 TMEM123 HAPLN3 AMDHD2 ATP13A1 PIM2 DAPP1 LILRA1 ALPK1 PSEN1 TRPC4AP SSH2 RRP12 FDPS SPHK1 ANKRD17 GLS NLRP3 ACOT9 SNX2 ROCK2 LRPAP1 SP1 DNPEP TXNRD1 SRGAP2 RBPJ ATG7 KAT2A ADAMTSL4 MKNK1 FPR3 CXCR1 DEFB1 VCPIP1 ZNF19 SEMA4A CTBS SLC46A1 OR52H1 SLC2A14 MTF1 DOCK8 H3F3B MSRA SLC25A20 PFKFB4 MAGED2 USP24 CSGALNACT1 FAM49A DIP2B MBOAT1 RAB15 TROVE2 CNP PHRF1 TMEM53 RAD9A DMXL2 PHACTR2 LIMK2 DCAF11 PDE8A HSDL2 ATPAF2 ATP11A FAM168A C1RL NT5C3 PRKCB CCNJL GFRA3 ARHGAP26 HIVEP3 MAGEF1 PRPF31 TIMM22 P2RX1 CHD7 ERO1L AFF1 MED17 FAM53C PANK2 KLHL26 ZGPAT NUDT22 MR1 KIAA0368 SLC18B1 ATXN7 DHX8 ZBTB49 PAK3 CDH24 RSPH9 NIPSNAP3B SMTNL1 FTSJD2 AMHR2 C14ORF159 FAM76A CCHCR1 SCLT1 H3F3C C21ORF33 TMEM255A ABHD6 PARP15 GPR97 APOBEC3H C22ORF28 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FOXRED2 CEP112 BIRC3 PTBP2 ICOS RBL2 YWHAE USP13 FAM109A CEP68 ATM PABPC4 TRAF3 CSNK2A2 ABCG2 ITM2A ELK4 PPIG ZNF318 ALG11 SIL1 PTPN4 G3BP2 FBXO3 RABEPK MTFR1 ZBTB44 KLF12 TFAM PMS1 UNC119B RCAN3 NBEA RPS26 RARB SYTL2 METTL23 RPS8 PTPN13 LMO7 HIST2H2AC CA8 TRIM2 ZNF460 RPL30 FAM214A SLC16A7 RPS13 TAB2 CD24 GSK3A DAZAP1 AKAP1 NDST1 TRIM65 ALDH1L2 CDKN3 MGME1 IGFBP2 KIF14 ALG14 ITGA1 CLDN7 TEX2 TTK MAP3K6 PLEKHA1 IL7R KLRB1 CHIC1 GDF11 COL18A1 ARVCF TRAT1 PHOSPHO1 CDYL KLF15 TRAK1 CRB3 GJB3 PYGO2 AXIN1 WNT5A CTNNBIP1 ASIP IPO7 WWOX DVL1 TCF3 CENPK PTPN22 CD3G CAMK4 SH2D1A CD160 CKAP2 HIST1H2AE ARHGAP19 CD2 CENPE CD84 COCH PALB2 C5ORF28 HAS3 GLT8D2 C1ORF56 AHR ELOVL5 TPPP3 VEGFA BTG1 SLC16A11 PDE5A ZNF780A NR1D2 RPL22 TRAPPC6B MATR3 BNIP3 RHOQ PDCD4 TMEM50B DYNLT3 EFNB1 RBBP4 RTKN2 MKNK2 SET FAM102B DUSP8 ADAMTS10 VAMP1 KBTBD8 SOCS2 HDAC9 IL23A NPDC1 TMEM120B BBC3 IRS2 MAFF FOXO3 MSL2 GNPDA2 CMSS1 EPDR1 ZDHHC6 PIGP MFSD5 AMD1 PSMD14 TMEM251 KPNA3 C15ORF61 GLRX2 IPO5 HEBP2 EXTL2 IER3IP1 TMEM55A MALT1 TACR2 SGMS2 TOB1 ARL6IP1 KLF7 NUFIP2 NOP14 ZNF32 C6ORF120 EID2B KLHL24 PRDM12 EMD NUP43 TRMT12 GPR183 GCAT RAD1 BTBD2 DLST HIST1H4E TMEM126B RECQL KIAA1279 ZNF791 NAA40 SMG1 MTIF2 EOGT NEB CCDC106 RBMX FOXD1 MECP2 CNNM3 ZBED6 CHUK ZNF304 PRKACB SCAMP1 PLK2 RCAN1 LETMD1 ANP32B PXK AMPD2 ZNF397 MEX3A ZNF280D BTBD8 ATF7IP SERPINB8 NR1D1 AMDHD1 RNF125 TIMM21 ANAPC10 SLC31A1 TRNT1 PEX3 UBA2 CAMSAP1 DPP8 CDK6 TSNAX FKBP14 COX20 APIP ZNF569 ZNF34 AIG1 ARL8A C11ORF58 TBC1D17 ERCC5 ZNF324 NDUFAF4 THBS3 ZNF558 GTPBP10 THEM4 ANKH MVK TMEM129 NFKBID SSH1 SPRED1 DCHS1 TUBB4A RPS6KA4 PPARA ADRB1 LRRN1 LCORL USP28 VSIG8 MPHOSPH6 ZBTB18 LIN7C HID1 RRAS2 SUZ12 PGM3 YAF2 FER1L5 ZBTB21 DYRK2 AKT2 AGGF1 IVD NANP RNF168 STK11 GOLPH3L ZNF175 TRIM52 ZNF284 ZMYM6 SPICE1 SNX13 ZNF398 ZKSCAN8 HYPK MTA1 POGLUT1 SLC27A5 SLC29A2 HSPA14 HOXA1 PEA15 RCN1 MCPH1 ABI2 RRM2B BIRC6 SDCCAG3 PPWD1 UTP15 MAP2K4 WDR70 SUPT3H ATF1 MAP2K7 CSGALNACT2 LIPN FITM2 EIF3L SLC4A7 C20ORF194 BICD1 ZNF550 TTPAL SKIL IL17RB CAPS STXBP6 LGALSL CASD1 FAM198B SRGAP3 UFSP2 KIF5C ZDBF2 HSPA13 ZNF146 C19ORF47 PDZD8 MTMR12 CHML ARPP19 NAA38 CNEP1R1 SUGP2 NMD3 NSA2 C2ORF69 MTX3 FRA10AC1 ZNF585A LSM3 MRPL43 ZHX3 LRCH1 FRG1 ZNF576 TBPL1 PPP2R3A TMEM41B TCTN1 MBTPS1 ZDHHC9 GPBP1L1 HIST1H2AK SOCS4 RBM12B IKZF5 TYW5 EPM2AIP1 C5ORF51 EZH1 OTUD3 PIBF1 SERBP1 ALG6 VPS13C THAP5 G2E3 PLK4 ZMYM1 VWA5B2 DIMT1 NABP2 AES CLYBL MARCH3 KIFAP3 ZMYND8 ADCK3 MCM8 MARCH9 MTRF1L ZNF584 PKNOX1 SENP5 ELF2 COIL ST7 STRIP1 METTL13 ZNF615 FYTTD1 RNF38 STRN SLC25A53 PHF2 POLR1E TIGD3 C11ORF21 FAR1 FCHO2 ZNF260 LYRM7 ZDHHC2 SCML1 FAM73A CCDC64 SNAPC4 LZTFL1 C4ORF21 IL8 ADO NIPA1 POLR3F DIS3 SPIN3 FBXO30 PRKCI AGL CCDC132 DNAJC24 C12ORF73 DAGLA GID4 USP46 ACAD10 CPSF6 RAVER2 ZNF595 SAP25 DEPDC5 AMER1 ERCC3 ECD EDARADD ZNF786 PITPNM3 TRIM33 ZNF420 ZNF347 DBT C8ORF76 C2ORF49 SURF6 PAFAH2 KCNQ5 ACVR2B ARL14EP ZNF490 DENND6B SCFD2 GJA9 FAM172A CXCR7 ZNF605 KCNG2 GTF3C2 TSTD3 HDC ERI1 RFX8 KIAA0355 ZNF678 SLAIN2 KRIT1 MTMR2 PLK1S1 KIAA1804 ZNF226 COG1 FAM211A DNASE2B WDR67 TSPYL5 KLHDC10 C12ORF76 KIAA1704 SLC25A43 ZSCAN5A CDADC1 ZSWIM7 C14ORF101 C10ORF88 TTC12 FAM92A1 EXD2 ZNF836 C9ORF123 C10ORF137 MAPKAPK5 MTCP1 NARR PGBD1 SEC61A2 INO80B PAFAH1B2 USP27X FUK CDC37L1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 TARS2 SARS2 TMEM37 MVP ABCC1 TMPRSS2 CD200R1L DNAJC11 NMI CAPN2 DDX58 NPC2 CXCL10 RIPK1 CCND3 SLC7A7 CACNA1D CYP2J2 IFITM1 ANXA2 CUL1 KCNQ1 LAP3 HSPB1 JAK2 HOOK3 ADA MPZL1 RAB8A HMOX1 RBCK1 OAS1 PTX3 MYO7B GNGT2 RELA UBQLNL STAT1 TRIM25 CNDP2 EPB41L3 EIF2AK2 TMEM173 POR OASL MOV10 ISG15 PTGES2 NUB1 MX1 ATP6V1B2 KMO ACO1 MGAT1 ENO1 SERPING1 MT2A TNFSF10 IFI27 FAM216B ECM1 S100P MT1E SMPDL3A MARCKS APOBEC3A SCIN CD300E S100A2 CCL8 ISG20 DHRS9 TMEM109 PLA2G15 UNC93B1 KCNK6 PDIA6 C1QC PIEZO1 PARP10 LGALS3BP TOR1B SHC1 PARVG SLC3A2 ARHGEF10L ITGAX C1QA XAB2 PTK2B EMILIN2 TYMP SPN CORO1B BST2 EHBP1L1 SLC15A3 HK1 APOL2 LTBR FBXO6 MYOF TIMP1 MILR1 VSIG10L SCARB2 CTSB CYFIP1 GLRX TMEM106A IFI44 ADAP2 FKBP5 NUDT16 FGD2 MS4A4A IRF5 MAFB C1QB CD163 SCIMP KPTN EPSTI1 ROGDI GAPDH HEBP1 C2 EPHB2 CBR1 EPS8 IDH1 BATF2 PTPRO SNX8 SPATS2L DTL KCNMA1 SPTLC2 RASGEF1B CDKN1A KLF11 MPEG1 AXL CD300C AGRN TMEM60 INPP5D ATF3 IRF8 FIBP ELF4 TCF7L2 CTSC FCN1 TNK2 HELZ2 PLXNB2 OGFR SLFN13 RSAD2 OAS3 IRF7 ZBP1 BARD1 IL18BP PLA1A TAP1 GPR84 IFIT1 CCL3L3 IFIT3 RTP4 TLR7 OAS2 CD86 PHF11 SIGLEC1 XAF1 CD274 APOL6 CCR1 DHX58 IL1RN TREX1 USP18 CMPK2 IFIT2 IFI16 PLAC8 PCDH20 HERC6 IFIH1 LGMN STAT2 PML NFKBIE ADAR GBP2 PARP9 PARP12 GCH1 HSH2D ADM TMEM171 GBP6 IFI35 PARP14 SOCS1 TRIM6 TRAFD1 SAMHD1 PPA1 PARP11 UBE2L6 TLR3 TRIL DPYSL2 EHD4 PSME2 KLF4 IER2 LY6E IGFBP4 PSMB10 DTX3L GBP3 FABP5 MAT2A IFI44L DRAP1 RNF114 NUPR1 TAPBP GIMAP4 HEXA FHAD1 GM2A DEK ATOH8 CLEC2B IL27 TRIM22 PLA2G4C CCRN4L PAPD7 CSRNP1 ZNFX1 LSM2 CHMP4A DYNLT1 DPP3 LYSMD2 TNFRSF21 MCEE PRPF3 CCT7 PNPT1 SNRPA LEO1 MAD2L2 RPS6KC1 FKBP4 PAPD5 APOBEC3C MN1 SAMD4A RIPK3 GNB4 MVD ODF3B SHROOM4 VAMP5 P2RY14 VRK2 NAGPA ANXA10 SLFN5 CASP1 IL15RA ZCCHC2 LGALS8 TRIM21 MOCOS USP25 TRIM56 FAM46A TRIM5 RBM43 TDRD7 TRIM14 PCGF5 IL15 CD38 RAB44 PRKD2 AARS IFI6 MT1X DCPS DDX60 DMAP1 C9ORF91 LIG1 TFPI2 RNF19B C19ORF66 TNFSF13B XRN1 SP100 RARRES3 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 GBP1 PAQR8 CORO2A HES4 KLHDC7B CDK17 ETV7 TICAM1 VAT1 PATL1 NAPA ERAP2 SP140L MDK RHBDF2 SMCHD1 WHAMM MOB3C TRIM38 FMR1 PIK3AP1 GTPBP2 TRIM26 FCGR3B RNH1 XPO1 ARHGEF3 GUCY1A3 ARMCX1 P2RY6 OSGIN1 SDC3 PLSCR1 HRASLS2 CD68 TNFRSF8 NCOA7 PPM1J PDE1B CCL22 SEMA4D COQ6 CD93 APOBEC3F NAGK SCO2 SIGLEC14 CARD16 BCL2L14 CASP5 FAM111A ARRB1 EGF HARS ERP29 GBA XPNPEP1 SNX6 PDCD1LG2 BAK1 HM13 PI4K2B LRRK1 CITED2 ANXA4 CTNNBL1 RIN2 HIRA DHDDS OPA3 EPHA2 PON2 TMEM123 P2RY2 PODXL SYNE2 BAIAP2 AMDHD2 ATP13A1 MFSD12 DDX39A TFEC DAPP1 TRPC4AP MAP4 SLC38A5 TTC7A ACP2 SASH1 GAS6 FDPS GLS PELI3 PRKCE DNPEP ABI3 GANC SSRP1 SRGAP2 GPC1 KAT2A ADAMTSL4 MKNK1 FPR3 TNFSF13 CYP27A1 MRPL40 DEFB1 SLC46A1 PTGIR RRBP1 POLD1 RCC2 CD2AP NOLC1 CASP10 CYSLTR1 H3F3B PLOD3 MSRA SLC25A20 TMEM51 HDHD3 MAGED2 NOP2 SEC24D TTC39B HHIPL1 ANXA6 GNA15 LY6D TROVE2 CNP NOC4L TMEM53 PHACTR2 SLC35F6 PALLD ATL3 SNTB1 GIMAP6 VPS33A SH2B2 NGFR KCNMB1 DES PLA2G16 SNRNP35 NHSL1 CADM4 PRKCDBP TIMM22 CHD7 CADM1 ERO1L MED17 RIN1 ASPHD2 IQSEC2 CPNE8 MR1 PAQR7 KIAA0368 DLGAP4 SLC18B1 FBXO44 CHRNB2 RUSC1 PAK3 TRIM44 CHST12 RSPH9 GSG1 FTSJD2 C20ORF118 C14ORF159 SCLT1 TMEM255A ABHD6 PARP15 APOBEC3H C22ORF28 GGT5 CEBPE Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SPTB UBL5 UIMC1 ATP13A3 HIST1H1C MME RBL2 ARRB2 PDZD3 FAR2 MPZL3 TMEM39B SRPK2 MEPCE NLRX1 MGAM HSPBAP1 TMED5 GUCY2C BDKRB1 CD244 FBP1 PTPN4 CASP3 SLC25A40 ZBTB44 PITPNC1 MPP7 FGFR4 ABHD3 SLC25A16 ZFP106 UNC119B PARP16 ADK BCL2A1 TMEM71 CDK2AP1 BEND7 REPS2 HIST1H2BC METTL23 HOPX CA8 STEAP4 RPL30 FAM214A SLC16A7 CYBRD1 FNBP1L RPS13 MPZL2 SLC12A9 MBD6 GSK3A VPS37C H6PD PLCB2 HCAR2 MGME1 TP53I3 TEX2 CPA3 KLRB1 CHI3L1 SLC25A29 PTGS2 COL18A1 MS4A2 PRDM8 YPEL1 CRY1 CLC TGFBR3 PHOSPHO1 TGFBR1 ZNF217 LAMA5 WNT5A SORL1 SLC45A4 PHF12 ST6GALNAC2 RGL2 PLEKHG3 ULK1 ATG2A PTPN22 IPCEF1 GNG2 ATP8B4 ASF1B SH2D1A CLEC4A GZMK IGF2BP3 CENPE MYBPHL CDH26 COCH CTSK IL1R2 CLEC4E PTGES LRRC4 SLC7A11 AHR SNRK ELOVL5 KLHL5 UBL3 SH3BGRL SERPINE2 TP53INP1 TMEM50B SAP30L EIF4E3 RAB11A EIF4A2 IVNS1ABP SAT1 VCL AGO4 ZDHHC18 ARRDC4 LST1 PI16 RGS14 MPZ CR1 P4HA3 SOCS2 IL23A ZNF841 HERC3 BCORL1 TP53INP2 PPP1R15B IRS2 ZNF816 EPDR1 YPEL5 UBLCP1 UBE4A AMD1 ACTR10 PPP3CA C15ORF61 PFN2 STAG2 TSEN34 NEK7 RB1CC1 SGMS2 ADORA2B PDE4B LTC4S KLF7 OGT ACRC FOXO4 TBL1XR1 MCU KLHL24 YIPF6 TXNDC16 CD46 PLCB1 CCDC153 TSPAN32 TSPAN33 GCAT TMEM40 CPNE2 CASS4 PELI2 CEACAM8 RP2 ORM1 KBTBD7 GMCL1 ARID4A BET1 KCTD12 CNNM3 ZBED6 FBXO33 SMURF2 IGF1R CETP LPCAT1 FEM1C PRKACB HERC1 KLHDC2 B3GALNT1 SRGN CDKN1B LTB HEXIM2 ZNF397 DENND3 CHST2 FRY XYLT1 BACH2 CLK1 CHKA PAG1 BACH1 IL1RL1 ADAM19 FAM101B FCER1A LPPR2 PYGM TLR8 BDKRB2 TRAF6 WDR82 PHF5A VPS36 PET100 RIT1 UBE2B GK KIT CDK6 GNAQ EGLN1 NR2C2 TMEM167A TSNAX ATG9A IFITM10 FKBP14 RAB21 GALNT1 ABHD12 ABHD5 TGM3 TBC1D17 TPCN1 ATP7A DIP2A C9ORF64 CUL3 BBIP1 CCNT2 PTPN12 TIGD7 TMCC1 MARCH7 KLHL21 KCTD7 EEPD1 ATP9A DBNDD1 PROK2 ANKRD22 RGS18 CYSTM1 TMEM154 LRRC32 RPS6KA2 WBP1L HEXIM1 SLC31A2 PDE3B RAB6A PPARA IGF2R HDAC4 BMX TGFA OSTM1 TDRD6 USP28 LPP CACUL1 SENP7 KCNH3 ZBTB18 CDK19 PIK3CB CCNG2 CBX7 IFT57 MSRB3 SLC12A6 AKT2 SLC19A1 ATG13 ATG2B IVD FBXW7 RC3H1 ZNF175 TRIM52 USP45 SNX13 ZNF398 CD300LB NUMB FAM167B PHKA2 SAMD8 POGLUT1 ZDHHC17 PPP2R5A MAP3K2 HOXA1 EYA3 ABI2 RRM2B TACC1 ZNF24 ZNF746 GNPAT ATF1 CSGALNACT2 LIPN SYNJ1 CYB5R4 CYB5R1 DENND6A EIF3L SLC4A7 C6ORF48 TTPAL TMEM55B MOK ZSWIM4 SKIL CLK4 STXBP6 PTAR1 CPD SULF2 FAM43A STK17B CCDC126 CEP120 NABP1 AGTPBP1 APBB2 LGR4 SENP2 DSTYK RASA2 TRAPPC8 PDZD8 CHML HTRA2 DHRS3 CNST RNF103 PPFIBP2 FBXO38 PHYH NSA2 EVI5 ZNF654 DIRAS2 STXBP5 HECW2 SOS2 DENND4A CNIH4 ATP11A HIGD1A TBPL1 TMEM38B APPL2 PID1 MED21 RBM12B ZNF776 ZNF614 ZNF845 SMNDC1 IKZF5 EPM2AIP1 ZNF770 CDK5R1 PDLIM7 EZH1 TNPO1 PIGX SLC12A4 KLHL2 RELL1 THAP5 OSBPL11 KIF1B TTC33 COL15A1 PPM1F ATP9B TMEM120A MLH3 ARHGAP42 DUSP11 SNAP23 ZNF766 ZNF652 PODXL2 THAP10 APBB3 ELF2 FOXN3 APOLD1 ZNF615 CNOT6L SLMAP UBE4B PHF2 TIGD3 IPMK C11ORF21 PHACTR1 RPRD1A FAR1 UBE2W FCHO2 LYRM7 FAM160B1 FAM73A AP1S2 KATNBL1 IL8 DIRC2 SF3B14 PQLC3 KLHL9 MAP3K15 CD300LD AAED1 SH3D21 SAP25 POLR2D PPP1R35 METAP1D ZNF853 MTMR10 TMEM216 CCDC125 DCAF8 BNIPL CNR2 DAW1 SNTB2 ZNF346 FAM200B EGFL8 AKTIP CCDC159 NMNAT3 ANKRD44 FAM172A C7ORF41 PION ZFYVE16 MAML3 ZCCHC8 OSBPL2 JMJD7 MOCS2 KRR1 DEF8 FAM211A TSPYL5 FAM92A1 SEC61A2 PAFAH1B2 EMR3 B3GALTL GLRB PDE6H TTC13 KLHDC5 FUZ PCNXL4 LYSMD1 CCDC111 PDE7B PNMA1 ROPN1L HDGFRP3 WDFY2 DHRS12 DUS2L PPM1M ZNF736 KLRC3 TMIGD2 RSPH3 C20ORF111 MYCL1 C11ORF30 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 TARS2 OS9 GCC2 PIGS ATP6AP1 SEC14L1 TMPRSS2 SQSTM1 DNAJC11 CAPN2 PCK2 DDX58 CXCL10 ACAD9 NEDD9 TUBA8 UBA1 NCL MPZL1 POLA1 HMOX1 MPZL3 PLCB3 OAS1 FCGR2A DNMT1 CTSD NUCB1 RELA TARS TRIM25 VARS EIF2AK2 TMEM173 USH1C FKBP15 OASL PXN MOV10 SIL1 ISG15 CD4 MAP3K1 DIAPH1 GOLGB1 MX1 TLN1 CPT1A ACO1 IPP NAGLU MKRN2 BCL2 RGS2 IFI27 ZEB2 FAM216B ECM1 NCKAP1 APOBEC3A ISG20 ABCA1 ARID5B PLA2G15 SYMPK MPZL2 UNC93B1 C1QC PARP10 LGALS3BP TOR1B PDCD11 RNASEL PARVG SLC3A2 ITGAX PGD XAB2 TGOLN2 LRRC25 EMILIN2 SPN CORO1B ITGB5 BST2 ITGAL PRAM1 HK1 APOL2 ITGA5 SLC6A6 LTBR FBXO6 MYOF TIMP1 EXO1 C1ORF162 NAIP IFI44 ADAP2 FKBP5 FADS1 MAFB PDSS1 CD163 SCIMP EPSTI1 EIF4G1 EPS8 TBL2 BATF2 SPATS2L DTL PDGFD A2M ABCF1 KLF11 GADD45B MPEG1 CD300C ITGA2B AGRN PLCD3 CLSTN1 CLU INPP5D ATF3 ABCA7 FPGS ELF4 TCF7L2 PSRC1 CTSC FCN1 TECPR2 DGCR2 HELZ2 C10ORF105 NUAK2 LFNG SMC2 SLFN13 RSAD2 OAS3 IRF7 DENND1C ZBP1 PLA1A TAP1 PLD4 SLC29A3 GZMA IFIT1 TKTL1 NEIL3 MYBPHL IFIT3 RTP4 OAS2 PHF11 SIGLEC1 XAF1 CD274 APOL6 DHX58 USP18 CMPK2 IFIT2 EVI2A IFI16 HERC6 AAK1 IFIH1 LGMN STAT2 RAMP1 PML SOCS3 ADAR GBP2 PARP9 PARP12 HSH2D ADM GBP6 SELP PARP14 TRIM6 SAMHD1 HAS1 THBD KLF4 DTX3L IRF9 GBP3 JUN IFI44L PLSCR3 LITAF ARRDC3 CA4 CSF1R MYLK MYLIP FNDC3B VWF GNS CD36 KIF26B FPR2 CLEC2B DDIT3 SLA IL27 C16ORF86 GP6 SIGLEC9 KLHL11 CYTH4 PLA2G4C CLSTN3 HMGN5 UNC5B ADRA2A ZNFX1 RBPMS2 ARMCX6 SLC29A1 GALNT7 SDC2 LEO1 TMEM245 GRB7 CKAP5 OGT APOBEC3C GP1BB SAMD4A RIPK3 DLG4 DHRS13 B3GNT8 SHROOM4 ANKRD9 ABL2 TAP2 BEAN1 SLFN5 TLR2 ZCCHC2 CSF3R SMOX USP25 FAM46A TRIM5 TRIM14 CCRL2 PDK4 LY6G6D C7ORF49 FPR1 AARS IFI6 SEC14L5 PIGL GPR63 DDX60 KIAA1211 SLC35E3 EIF3A LIG1 C19ORF66 SP100 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 SAMD9 GBP1 CHD4 GLG1 PAQR8 CORO2A ATRX RFWD3 NAA25 KLHDC7B CHST15 SEC31A SP140L SMCHD1 BTN3A1 TRIM38 BTN3A2 PIK3AP1 TRIM26 CTSA FCGR3B PTGS1 MYL9 XPO1 PLEK ERBB2IP GUCY1A3 ZNF70 P2RY6 EID3 SEMA7A FADS2 SAMD10 ITGB3 KIAA1549L SDC3 P2RY8 APBB1IP CD68 PLXNB3 TNFRSF8 PUM1 SF3B3 CCL22 SEMA4D COQ6 FUT7 SIGLEC14 SPEN TNFRSF1B FAM111A EGF MFSD2B GBA IFITM10 PDCD1LG2 PI4K2B ATP6V1H ASAH1 HIRA EML4 USP8 TEP1 PLEKHM1 ENG AMDHD2 POLR2A ATP13A1 RNF185 NEXN ALPK1 TPP1 ATP6V0A1 ACP2 NOC2L CTTN PELI3 ROCK2 GCLC SSRP1 PDE9A TSPAN15 RDH11 ZCCHC6 AMBRA1 TLR5 HIST1H2BJ KAT2A SLC26A11 CYP27A1 DEFB1 ENOSF1 SLC46A1 BTN2A2 LTBP1 GBF1 TUBB1 ABCA6 ADRA1D SLC23A2 TTI2 TDP1 RCC2 DOCK2 H3F3B RILPL2 CLN5 ARHGEF2 SLC25A20 F11R MAGED2 NOP2 ZC3H4 USP24 LPIN2 RPGRIP1L MANBA TUSC3 PHIP KDM5B NOC4L TMEM53 GPRIN2 ARHGAP21 ATRN SNX18 EMB DHRS3 ZNF609 PHF21A PFKP SLC35F6 HSDL2 KIAA0754 NCKAP5L PALLD ZNF441 TMEM117 HIRIP3 TM9SF4 EHD3 ARMCX3 GFRA3 DES KIAA0586 TAF6 C3ORF62 KIAA0196 NHSL1 HIVEP3 KIF24 LYSMD4 PRKCDBP ADCK1 P2RX1 CHD7 AFF1 RIN1 KLHL26 IQSEC2 MTBP MR1 DNAJC13 KIAA0368 DLGAP4 CHERP KCNN3 ACRBP C3ORF18 ZNF512B CHRNB2 ILF3 KDM8 COG7 KIAA1429 HIST2H3D NCOA6 POM121C PLEKHM3 ZBTB49 PLXDC1 PAK3 TRIM44 ATCAY B3GNTL1 CDH24 CHST12 GNPTAB ZNF527 MDM1 CLASP1 SCLY NT5M C20ORF118 FAM63A C14ORF159 QTRTD1 CCHCR1 SYTL4 ZNF837 GLB1L SEZ6 SEPN1 TMEM255A HKR1 MS4A8B INTS9 KCTD21 DAGLB RNF175 CMTM5 MTERF DDX59 FAM21C C1ORF85 C6ORF70 LY6G6F KIAA0317 CCDC36 CLPSL1 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B TIMM10B UBL5 RPS27A IL1B TBCA ATP13A3 UBE2D2 EIF3F GHITM RPL12 HIST1H1C VPREB3 TMEM65 GABARAPL2 UBE2D1 ZNF274 FAR2 TUBA1A NLRP6 RAB18 FBL ARL6IP6 NDUFB9 MGAM DHRS11 HSPBAP1 PPIH TMED5 BDKRB1 FBP1 THTPA UBFD1 FBXO9 AP4S1 RABEPK LYPLA1 ZBTB44 UFC1 FGFR4 PAIP1 SLC33A1 FN3K PROZ RWDD3 NDUFB6 RNF167 PARP16 ADK ATP6V1G1 FAM108A1 RPS17 RPS26 RPL21 RPL35A CDK2AP1 RPS12 HS3ST1 RPS11 HES1 RPL27 METTL23 ZFP1 RPS8 CA8 PAWR TRIM2 GALNT3 RPL30 C12ORF75 CKS2 FNBP1L RPS13 BEND5 RPL7A CHCHD10 NEDD4L RPS27 BANF1 GSK3A VPS37C GRINA SLAMF8 NDUFB5 PNP ZWINT TUBG1 CDKN3 SHCBP1 POMP KIF14 PRDX1 SNAPIN NME1 VPS25 TEX2 COX5A PKMYT1 OSTC MTHFD2 YPEL4 MPP6 CMTM2 MIB2 CPA3 PTGS2 COL18A1 ARVCF CLDND2 AUH RMND5A CDYL MUTYH PLAUR FAM20A JMJD6 SLC26A4 MAF WNT5A CTNNBIP1 HNRNPH2 RAP1A DCK DVL1 MRPS36 BRPF3 ATP8B4 CD160 CLEC4A RETN CDH26 CLEC4E AIDA AHR PCBP2 UQCRB PTGES3 YBX1 PPP1CB MORF4L2 NDUFA3 MED18 CHCHD2 RPL5 NGFRAP1 CYB5A CRIP1 EEF1B2 RPL10 SLC16A11 SERPINE2 RPS5 RPS21 EIF3K NDUFA13 MRPL20 PSMB5 MORF4L1 CCNI JUND NDUFB11 RPL18 RHOQ TMEM50B NDFIP1 C10ORF10 FDX1 RGCC PSMB4 SAP30L SEPW1 CHORDC1 KRTCAP2 TRMT112 NDUFC1 ERRFI1 NDUFA1 RAB11A DNAJA1 RBM3 ANXA1 RPS3 SEC61G SAR1B SSR3 TMEM147 CACYBP ARRDC4 DEFA3 CR1 KBTBD8 HDAC9 FAM129C TMEM120B GPX3 BRD1 DPY30 OST4 UBE2S SEP15 GGPS1 CMSS1 BABAM1 GYS1 EPDR1 HMGB1 PARK7 LAMTOR5 IMMP1L SPIN2A TMEM230 NPM3 NDUFA12 ATP5L SKP1 SPCS1 UXT DCTN6 C15ORF61 NAA10 HEBP2 MPLKIP SEC23A CCDC109B ZBTB8A TACR2 SGMS2 ADORA2B MRPS6 ACRC CREB3L4 FAM46B RND1 CD46 SNX15 RPA3 PTS SLIRP TCEB1 GPR183 FCRLA BCL11A ATP6V0D2 HIST1H4E CELF6 TMEM126B ORM1 KBTBD7 DCTD SLC25A28 LRIF1 CD58 C17ORF67 CNNM3 ASB8 SIKE1 CETP FEM1C TPRA1 PRKACB TMEM238 FAM210B RPL23A GNB2L1 SERF2 CHP1 GRAMD1B CHST2 ENTPD1 CHKA STK17A FCER1A ALPK3 PRDX2 BDKRB2 PEF1 COPZ1 POLR2H VPS29 TIMM21 EXOSC1 VPS36 TXNL4A PPA2 PET100 COX11 TEN1 PEX3 RNF11 NR2C2 STX7 ESD TXNL1 ZIK1 UBALD2 FCF1 TOMM22 ATG12 RAB21 SNRNP27 NTAN1 C12ORF45 AIG1 CDC42BPB CMTM7 ABHD12 CNPY2 TGM3 SMARCB1 NIPA2 DYNC2H1 DNAJC21 ZSCAN30 THOC7 KCTD7 BOLA1 EEPD1 MAZ MPC1 CMC2 PROK2 ANKRD22 NFKBID PPP1R14B C19ORF48 TNIP2 EGLN2 RAB6A USF2 CDC34 GTF3A TPTE2 MPHOSPH6 HID1 SUZ12 TRA2A AKT2 SLC19A1 STK11 ZNF175 TRIM52 ZNF383 HYPK FAM167B PHKA2 TGIF1 HOXA1 PEA15 HAX1 SIAH2 CCNH UTP15 HRK USE1 ATF1 SPSB1 FAM96B AHCYL2 MRPL23 ANAPC16 FITM2 BCL7C EIF3H TOMM7 TANC2 C6ORF48 ZNF550 TTPAL SKIL CLK4 CAPS DPCD FAM173B STXBP6 MYL6B NDUFB8 CPD DCUN1D1 CCDC126 KIF5C HSPA13 ADAT3 LGR4 ALKBH7 CCDC167 ZNF778 ATP5G1 PIP4K2A ATPIF1 C14ORF2 PHYH MYCBP NSA2 MRPS14 LSM3 COMMD5 MIA WBP1 CNIH4 DUSP23 HIGD1A TBPL1 TMEM38B VMA21 ANKS6 TCTN1 REXO2 DNAJA2 HIST1H3E SMNDC1 IKZF5 CDK5R1 KCNK7 DUSP14 RELL1 ZMYM1 COL15A1 ELOF1 LSM6 GTF2A2 AES LRRC28 GAB1 ARHGAP42 ITGB1BP1 MARCH9 AAMDC OCEL1 THAP10 C14ORF142 ISCA1 MEMO1 ZNRF2 PHF2 TIGD3 IPMK PNPLA8 C7ORF73 UBE2W CNIH LYRM7 PGM2L1 SLC25A6 FAM89B ATP5I TMEM64 AP1S2 METTL21D PLEKHA3 LSMD1 SF3B14 MRPS17 PTRH2 LSM1 CORO7 FBXO30 MED31 KDM1B CD300LD AAED1 RAVER2 MBOAT4 SS18L2 METAP1D MAP1LC3B2 TMEM216 ATXN7L1 HOMER3 MRPL36 DAW1 GPANK1 FBXO22 PUS3 ZNF570 NGRN FSD1L DENND6B C16ORF87 ALG13 CXCR7 CAMK1D JMJD7 HIST2H2AA4 CHCHD5 ZNF547 ZSWIM7 C9ORF123 PDE6H PDE7B DHRS12 PPM1M MYCL1 C6ORF1 KCNJ14 C12ORF40 PNOC MNF1 C11ORF75 PANK4 CCDC13 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBB SPTB SUMO1 TARS2 BCL2L1 SARS2 HSPA5 LARP1 DNAJC11 UBXN6 THY1 CXCL10 EPB41 MYO1D ACAD9 CTLA4 RNPEP PKM TUBB4B SPTA1 AP2M1 PITRM1 POLA1 GPX1 CRISP3 PSMD4 HBQ1 COPB2 DNMT1 PTX3 MARK3 TST TUBA4A VARS SIRT5 OASL STOM ISG15 HBM PPIA FBXO9 SLC25A39 KLF1 CD55 FN3K NUPL2 FECH PSMA2 RPS20 ENO1 RPS17 HIST1H2BH RPL9 BEND7 IFI27 RPL41 RPS15A MT1E NDUFB2 RPS3A TRIM2 APOBEC3A C12ORF75 SCIN HIST1H2BD HIST1H1D RPS7 RPL7 NEDD4L FTL PLA2G15 BAX PNPLA2 STT3A LGALS3BP GRINA SPN BSDC1 EHBP1L1 HK1 DDB1 SLC1A5 PLK1 MYOF TOP2A CCNA2 CLSPN TK1 CCNB2 CTSB GTSE1 CDKN3 SLC16A1 E2F2 PSEN2 DEPDC1B SPAG5 RAB13 MCM2 KNSTRN ASPM AURKA GPNMB RRM2 BIRC5 NDUFS4 H1F0 GALK1 KIF15 HEBP1 KIF11 BRCA2 TPX2 EPS8 CEP55 CDC20 KIF23 CENPW HP MKI67 DTL NKIRAS2 NCAPG TCN1 PHOSPHO1 RMND5A ABCF1 SLC2A5 BMP4 ELANE CTSG FOXM1 LTF ELMO3 SLC7A5 CLU NLK MMP8 MAP2K3 FPGS CTSC MS4A6E IQCE ZNF628 PRR12 SMC2 E2F8 GRAP2 KLRC1 DENND1C TCF19 RAD51 SH2D1A NCAPD2 GZMA CHIT1 MCM5 IFIT1 CCNF NCAPG2 HMGB2 GZMK TNNT2 MYL4 PHF19 CHAF1A CMPK2 EVI2A PAQR9 HBB SLC4A1 SNCA PLAC8 PREP HERC6 RNASE4 INHBA HAS1 PPY PCOLCE2 SVOPL NAP1L5 TNS1 SELK TGM2 COX17 CDC42EP1 CA2 UQCRC2 TMEM176B NDUFB3 PTGR1 SRP14 CA4 S100A16 WNK1 SERPINB6 SELENBP1 POLR2K USMG5 GUK1 GLRX5 HAUS4 DBI SERINC3 GPX4 MYZAP DEFA3 FGB C17ORF99 BPI OLFM4 ZNF596 ZNF554 SLC14A1 TMEM213 FOXO3 BABAM1 GTF2E1 WBP2 RRM1 MND1 GYS1 MSRB2 FAM216A AIFM1 ARMCX6 SLC29A1 MRPL13 DPP3 ZMAT2 ANP32E NOSIP MRPS23 SMIM6 FAM96A PCMT1 CCT7 ABCB10 RPP40 ERH LEO1 SNRPE ETFB DDB2 TMEM245 NCOA4 KHDRBS3 E2F7 MKRN1 CKAP5 HIST1H1A FOXO4 SRXN1 RIPK3 ATAD2 CDCA7 MCM6 NIPSNAP3A ANKRD9 MRPL47 PTS VAMP5 FEN1 S100A8 DNASE2 SMOX IL15 LY6G6D PRG2 TPGS1 OLR1 CCDC15 TFRC CDKN2C TESC AARS NUDT1 IGLL1 VNN1 TSTD2 ORM1 MCM4 TTF2 MCM7 C10ORF32 TMEM56 AMFR MRPS11 GBP1 CHD4 GMPR CTNNAL1 FAM210B BPGM ACTN1 MYL6 AZU1 BLVRB TCEB2 PRTN3 R3HDM4 MPO GZMB GUCY1A3 ARMCX1 CENPV SDC3 TMSB15B IL21R PRDX2 PSMD9 EXOSC7 RIOK3 CLPX MRAS BSG TFR2 STARD3NL SNX6 FKBP3 NECAP2 PSMC5 HMBS GID8 HAGH PSMC3 WIPI1 TMEM9B GNG3 PPM1A NXNL2 TPM1 GSTO2 ALAD CMAS BLOC1S1 BST1 C11ORF71 MPST CTNNBL1 CCS ABHD4 CHST10 WDR81 AMDHD2 ASB1 SMIM5 F8A1 ZFAND2B PARVB KCTD20 MOAP1 KANK2 UROD RBM6 GUCD1 FAM214B MAF1 AAGAB RNF123 TNFRSF11A PC GCLC FXN SSRP1 TMPRSS9 BACE2 RDH11 FIS1 HIST1H2BJ CYP27A1 DAP DEFB1 FBXO4 GALK2 MTHFD1 ALDH1L1 RANBP10 PSMF1 CRAT PPIF MCM3 MAPK12 CDKN2D NEIL2 IFRD2 FBXW2 PRDX6 CCDC134 TXNDC9 TMOD1 JOSD2 CTDSPL DUT NOP2 NOL6 ANKRD40 SLC25A37 C7ORF50 NFIX DSC3 ICA1 C1QTNF6 NOC4L HIPK1 STX2 NSMCE1 PIP4K2A UBE2O HSDL2 RPAP1 PALLD ATPAF2 PHKA1 HIRIP3 SYNJ2BP-COX16 CD99L2 HDAC11 BPHL HIST1H3I CCDC88C RNF10 VPS33A ST6GALNAC4 CCNDBP1 DCAF12 MMP28 GFRA3 AVPR2 TMEM63C TAF6 DAB2 MINOS1 NHSL1 ASCC2 ZNF622 PROSER1 PTPMT1 GPR146 UROS SMAP1 PSME4 UBAC1 ISCA1 FAM46C EPB42 MPP1 CTPS2 STRADB TCTN2 TMEM106C INA MR1 SPSB2 EXOC7 PAQR7 KDELR3 DLD FLYWCH2 TSSK3 SLC43A1 TUBB2B NENF WDR73 COG7 MRPL53 HIST2H3D RCL1 BSCL2 XK RSPH9 GDPGP1 ATP5S LYRM9 ZNRF1 ZER1 TRIM39 CCHCR1 ENOX2 IL12RB2 GLB1L APOBEC3H KLRC3 DDX59 C6ORF70 TRIM58 WDR45 STK16 C9ORF174 MARCH2 PPP2R5B DEFA1 PM20D1 C4ORF52 HYAL3 EPB49 DCLRE1B PPAPDC3 PRG3 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B PIK3R2 PDCD1 ERGIC1 TOM1L2 HIST1H1C VPREB3 ZZEF1 ZNF274 HSPB1 CD200R1 FYCO1 UHRF2 NCKAP5 TLE1 HSPBAP1 ING3 TGFB1 BDKRB1 GNMT AGBL3 PCMTD2 NR3C1 VPS13B ABHD3 SLC25A16 PROZ HOXA7 TMEM186 RPS6KA5 CHEK2 KRT18 IL5RA HS3ST1 NFAT5 HIST2H2AC CA8 KIAA1324 ZNF460 SLC16A7 FNBP1L RPS13 BEND5 PLA2G7 TPD52 CHCHD10 C2CD2L DAZAP1 PLCB2 GIGYF1 RHBDD2 ALDH1L2 MGME1 CLCN4 ALCAM TMTC2 CMTM2 PER3 AKAP5 CCR9 COL18A1 ARVCF MS4A2 SPON1 KLF16 TUFT1 CDYL KLF15 CRB3 HPGDS FAM20A JMJD6 SCRIB MEF2C SLC26A4 PYGO2 MAF AXIN1 WNT5A ASIP WWOX DVL1 DYRK1B ZNF865 KDM4B BRPF3 ZNF710 SOAT2 CYSLTR2 ARMC7 CD160 PGAM2 CD19 NFKBIE SOCS1 TLR3 LGALS12 C1ORF56 BTG2 TSPAN13 PTGES3 RAMP2 BTG1 SLC16A11 SERPINE2 TAGLN BNIP3 RHOQ C10ORF10 SAP30L CHORDC1 HSPH1 JDP2 ERRFI1 RBBP4 DNAJB1 RTKN2 MKNK2 PHLDA1 NXF1 FXYD1 ARRDC4 MFHAS1 ZC3H12A TAGAP P4HA3 UCMA DCUN1D3 KBTBD8 HDAC9 NTNG2 ZNF292 TMEM120B GPX3 SLC25A27 BRD1 DUSP5 CLCF1 MAFF TSC22D2 BTAF1 FOSB SH2B3 MSL2 GNPDA2 DEPDC7 ACIN1 AP1S1 MAGED1 SPCS1 CDC16 CCDC117 ERO1LB ZNF317 ZBTB8A TACR2 ADORA2B PDE4B LTC4S NUFIP2 TSPYL4 PIK3C2B VEGFB FAM46B MAML1 CLIP2 KDSR CD46 EMD TATDN2 NAALAD2 ZC3HAV1 SPPL2A PCGF5 RIPK2 POU2AF1 FCRLA DERL3 TSPAN33 STAP1 BTBD2 DLST GPR137C HIST1H4E CASS4 TESK2 LRIF1 BCL10 RBMX MECP2 GLIS3 CNNM3 ZBED6 KBTBD6 SCAMP1 TMEM238 CD83 ZNF581 BLNK PHACTR4 CMTM4 GPSM3 MS4A1 ZNF397 CHST2 LONRF1 BACH2 CHKA APBA1 IL1RL1 CHN2 CR2 KLHL14 RNF125 BDKRB2 TIMM21 HHEX KIT CDK6 TFEB NR2C2 PAX5 SP140 TP53RK TRIM11 ZNF569 ARL8A CMTM7 ABHD12 ABHD5 ORAI3 ZNF324 PHC3 DIP2A ZCCHC7 RBBP6 MTA3 CCNT2 HERC4 MEF2D KCTD7 ULK3 PLEKHM1 MAZ FBRSL1 DBNDD1 STRN4 NFKBID EPC1 ELK3 VPS13D SSH1 ZNF160 LRRC32 FAM219B SLC31A2 EGLN2 VAMP2 ZNF699 LRRN1 KDM4A TDRD6 LPP KCNH3 ZBTB18 ZBTB4 HID1 PDGFB TRA2A CBX7 R3HCC1L FER1L5 ZBTB21 COL10A1 AKT2 TARDBP ATP2A3 SLC19A1 ATG13 BLK CRTC2 IVD ADAMTS13 MFN1 RABGAP1 CD79A TRIM52 ZMYM6 ZNF398 PIGG SUCO TTBK2 FMO5 POU2F1 MAP3K2 PEA15 TERF2 MCPH1 EYA3 ERN1 HRK CASP10 MAP3K10 ATF1 OXR1 SYNJ1 LEPROTL1 KIAA1147 SLC4A7 KANSL3 ZC3H10 GMEB2 ZNF335 ARID3B BICD1 ZNF550 TTPAL ZNF140 ZSWIM4 IL17RB CAPS FAM173B LIG3 SULF2 FAM43A STK17B APBB2 CAPRIN2 C19ORF47 ADAT3 WDR20 RASA2 RBM15 MTMR12 CHML BTBD7 TMED1 DESI1 SEMA4F SOS1 MTX3 SNAPC3 HECW2 MIA WBP1 CBX6 LRCH1 MPRIP RANBP3L PPP2R3A APPL2 FCRL1 FCHSD2 TCF20 PLEKHA2 VAV2 RBM12B SMNDC1 IKZF5 EPM2AIP1 SNX16 TRIM45 EZH1 OTUD3 HIC2 PIBF1 BTN2A1 FAN1 DUSP14 RELL1 PRDM10 COL15A1 ADARB1 FAM219A FBXW8 KRTCAP3 CLYBL SPAG1 ENTPD7 C6ORF136 ZNF766 PWWP2A FAM193A MCM8 GPR153 MARCH9 SENP5 APBB3 INVS GNL3L APOLD1 CADM1 RORA STRN PHF2 KAT8 SLC35E1 ZNF418 GNG7 PPP1R12B MAP9 FCHO2 LYRM7 C16ORF52 CCDC39 ZNF358 MEIS3 CTDSPL2 KATNBL1 LMBRD1 CTDNEP1 DIRC2 ZC3H12B TCEA3 TMOD2 TMED8 PCNX PQLC2 ACAD10 SRSF10 CPSF6 MYEF2 RUFY3 ZNF287 MBOAT4 SAP25 TRMT61A AMER1 ERCC3 CCDC141 STK35 RNF169 MIER2 EDARADD INPP5F RRP8 ZNF786 PCDHGB7 ZNF343 TRIM33 BNIPL CNR2 DBT ZNF570 FSD1L DENND6B STXBP4 GATAD1 BAIAP3 GJA9 ZNF354B FAM172A CXCR7 GNAT2 RNF220 KCNG2 ZC3H8 CAMK1D KRBA1 MAN2A2 KRR1 HEXDC MEGF11 ERI1 MST4 SLAIN2 COG1 TSPYL5 C14ORF101 C10ORF88 FAM92A1 MTCP1 FUK PDE6H PDE7B DHRS12 PPM1M MYCL1 C12ORF40 PNOC PANK4 RPRD1B C19ORF81 MAMU-DOB RBM23 NAA60 NOP9 FBXO48 SFT2D3 TMEM14E PHF15 RLTPR AIRE ZBTB46 AHI1 ZBTB37 IRX3 LDOC1L VPS37A CEND1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBB SPTB UBL5 BCL2L1 EEF1A1 LARP1 DNAJC11 CSDE1 UBXN6 DPEP1 EPB41 MYO1D JAKMIP1 RNPEP RBX1 SPTA1 AP2M1 GPX1 CRISP3 CALM3 PSMD4 MARK3 TST TUBA4A TARS VARS USP54 STOM TLN2 MOB2 GUCY2C HBM FBXO9 SLC25A39 PKIG BRI3 KLF1 RILP CD55 RWDD3 FECH RPS20 PFDN5 RPS17 RPL9 BEND7 LSM12 RPL41 RPS15A TPT1 RPL6 S100P MT1E RPL38 PBX1 HIST1H1E NDUFB2 HIST2H2AC RPS3A HEY1 RPL23 COX6A1 RPS25 SCIN SLC2A1 RPSA GADD45A RPS29 RPLP1 RPL11 RPS14 RPS7 RPL7 NEDD4L RPS27 RPL27A FTL BAX PNPLA2 ENPP4 GRINA FKBP8 BSDC1 DDB1 CREG1 SLC16A1 E2F2 PSEN2 ADAP2 KIAA0930 RAB13 MCM2 FADS1 GPNMB NDUFS4 H1F0 KIF15 GSTO1 HEBP1 BRCA2 TPX2 IFI27L2 PDGFD TCN1 CLC PHOSPHO1 AUH HINT1 RMND5A TRAK2 CNOT6 ABCD3 SERPINF1 CYP4V2 ELANE CTSG LTF SLC7A5 EEF1D RHOU CLU ANKRD6 MAP2K3 MS4A6E ARHGAP35 GRAP2 KLRC1 KNTC1 GZMA CHIT1 GZMK CCL3L3 COX7A1 TNNT2 RETN ALOX15 MYL4 THRSP IFIT1B ZRANB3 CMPK2 ALAS2 PAQR9 HBB SLC4A1 SNCA PLAC8 RNASE4 PPY MICALCL SVOPL TMCC2 ACER2 PCBP2 THBD TOX2 TNS1 SELK HMGN1 PPP1CB MYL12B CHMP4B TGM2 ADIPOR1 COX17 TXN RPS23 CA2 RPLP0 LYZ RPL26 RPL4 PTGR1 SRP14 PCNP CA4 NDUFA2 ROMO1 S100A16 MPC2 MXD4 TUBB2A MYEOV2 SERPINB6 SELENBP1 GNG11 NDUFA4 USMG5 GLRX5 CHCHD1 DBI RPS27L GPX4 BNIP3L ZNF880 DEFA3 C17ORF99 SLC5A10 BPI OLFM4 S100A12 KLHL11 ZNF596 SLC14A1 FOXO3 OST4 BABAM1 WBP2 GYS1 MSRB2 SLC25A11 MRPL13 GPR160 ZMAT2 SDC2 SLC25A15 BOLA3 ANP32E NOSIP SPIN1 WDR83OS SKP1 NIT2 ABCB10 LEO1 PRKRIR EBPL RPL32 MRPL11 MXI1 NCOA4 MKRN1 SRXN1 MEA1 ATP5E NIPSNAP3A ANKRD9 SLC6A9 S100A8 DNASE2 LY6G6D ZMYND10 PRG2 TPGS1 CCDC15 TFRC CDKN2C TESC NUDT1 IGLL1 TSTD2 GYPC TMEM56 AMFR ADAT1 GMPR CTNNAL1 NOSTRIN FAM210B BPGM TM7SF2 SERF2 MYL6 AZU1 BLVRB TCEB2 PRTN3 R3HDM4 MPO CD52 RPS6 COX6C SLC25A42 CENPV FHL2 LAMA3 TMSB15B HPD ADD2 AIMP1 PRDX2 GATA1 PSMD9 VPS29 PEX2 RIOK3 CLPX MRAS RECK BSG RNF11 TFR2 SNX6 NECAP2 HMBS GID8 IFT20 HAGH ZMYM4 WIPI1 TMEM9B TMEM183A ZNF629 PPM1A TPM1 GSTO2 DCUN1D2 ALAD C9ORF78 C4ORF3 C6ORF62 BLOC1S1 C11ORF71 MPST CCS ABHD4 KTN1 RPF1 PON2 MZT2B F8A1 KANK2 UROD DTX4 UBE2J2 GUCD1 FAM214B MAF1 KAT2B AAGAB RNF123 PC GMFB GCLC FXN CDC34 TMPRSS9 BACE2 THUMPD2 FIS1 PRR5 HIST1H2BJ DAP STK11 DEFB1 SESN3 ZNF19 ALDH1L1 MPP2 RANBP10 PSMF1 GCLM ABCA6 ALOX12 SLC18A2 CDK8 MAPK12 EPOR RANBP6 NEIL2 RBM38 IFRD2 FBXW2 PRDX6 TXNDC9 TMOD1 MGST3 MRPL23 JOSD2 GPC4 EIF3H USP24 NFXL1 SLC25A37 C7ORF50 TRAPPC2L CARHSP1 FHDC1 NFIX DSC3 DCUN1D1 C8ORF37 RSL24D1 IGF2BP2 ICA1 C1QTNF6 ARHGAP21 HIPK1 STX2 EML2 MYOM1 CLPB PIP4K2A UBE2O C14ORF2 PAOX SVIP FUBP3 TTC28 HDAC11 NUDT7 CCDC88C RNF10 HIST3H2A PHPT1 ST6GALNAC4 DNAJC1 PLCL2 CCNDBP1 DCAF12 PITHD1 UBALD1 GFRA3 AVPR2 DES SSBP3 NUS1 UFD1L MINOS1 ASCC2 PTPMT1 TBC1D24 CLK3 GPR146 BLM POLL XPO7 UROS SPECC1 SMAP1 MRPS28 PTDSS2 UBAC1 ISCA1 FAM46C EPB42 MPP1 STRADB ZFPL1 GCFC2 POC1B SF3B14 ERICH1 TSSK3 DOK6 CSRP2BP SLC43A1 ACSL6 TUBB2B ILF3 METTL20 NENF MRPL53 MED28 NSMCE2 PGA4 HIST2H3D CRBN DCAF8 BSCL2 TRIM44 B3GNTL1 XK ATP5S LYRM9 ZER1 POLR1D SYTL4 WWC3 SEPN1 TMEM255A APOBEC3H CEBPE KLRC3 MTERF DDX59 TRIM58 WDR45 MARCH2 PPP2R5B DEFA1 C4ORF52 HYAL3 EPB49 PPAPDC3 PRG3 ICAM4 ZNF502 MARCH8 SLC35D2 USP40 AHSP FAM104A C22ORF32 TATDN3 CCDC23 C10ORF116 C11ORF57 ANO2 ZNF792 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GNA11 CD79B IL1B STAT3 CTDSP1 PPP2R1A DDX58 SCAP ESRRA MAST4 PDZD3 FURIN ZBTB7B SIGMAR1 RNF41 NLRP6 MPZL3 TRIM25 TMEM176A AASS TLE1 SRPK2 EIF2AK2 RCC1 SLC23A1 HSPBAP1 USP21 AAMP PPIH HSPA8 AKAP8L BDKRB1 TMPRSS13 RAB5C GNMT ABHD3 PROZ MCAT IKBKB C1ORF63 CHEK2 KRT18 HS3ST1 ZFP1 PTPN13 CA8 PAWR ZNF460 SSBP2 DHRS9 CHCHD10 RELT TMEM184B MPZL2 C15ORF39 VPS37C SF3B4 MYADM SH3BP2 PIP5K1C B3GNT7 LMNA ZSWIM8 SLC15A3 RARA ITGA5 ARHGDIA RHBDD2 KIAA1958 ZWINT FZD2 HVCN1 ALCAM NETO2 ACVR1B CLDN7 KIF20A ENPP5 CRIP2 C16ORF54 RHEBL1 CCR9 PTGS2 COL18A1 PRDM8 KLF2 MUTYH SERHL2 TRAK1 CRB3 OSM JMJD6 RARG MEF2C LRP5 WNT5A CDK2AP2 GOLPH3 CMTM8 DYRK1B FOSL2 PHF12 HELZ2 NUAK2 SBNO2 ATG2A ERF IRF7 PARPBP RACGAP1 ITGB7 ARHGEF39 PGAM2 PSAT1 IFIT3 DHX58 TREX1 EFCAB11 IFIT2 CCNE2 CD19 TIMELESS IFIH1 SOCS3 NFKBIE GBP2 HSH2D GBP6 SOCS1 TRIM6 TLR3 GLT8D2 SCN3A C1ORF56 AHR BTG2 TSPAN13 PTGES3 ZFP36 FOS DUSP1 ELOVL5 DTX3L SMAGP AMMECR1L ZNF780A PSMB5 TAPBP TM9SF2 BNIP3 TSC22D3 ICAM2 PIM3 HSPH1 ERRFI1 DNAJB1 MKNK2 ZNF692 VPS35 MFHAS1 ADAMTS17 FAM187B RAB30 TAGAP HSPA6 CCR4 P4HA3 HDAC9 LIMD1 BBC3 IER5 IRF2BPL CSRNP1 MAFF NFKBIZ TSC22D2 FOSB ZBTB34 SH2B3 UBE2A PSME3 STIP1 TMEM230 UBE4A TMEM185B SPCS1 PITPNB TUFM CCDC117 ZNF317 CDC25B TACR2 PDE4B KLF7 ORAI1 MAML1 CLIP2 PRDM12 ZBTB2 REL URB2 PPP3R1 NUP43 TATDN2 SPATA7 TLR2 CD40 MB21D1 MARS2 TDRD7 RIPK2 CXCR5 C7ORF49 FCRLA WAS WDFY4 IL27RA SPIB CASS4 RP2 IFI6 SIGLEC10 MCM4 EOGT GPATCH1 RNF19B FASTKD3 LRIF1 IFIT5 TMEM140 GBP1 CNNM3 FAM110C PATL1 TMEM62 CHSY1 PIK3AP1 GPSM3 MS4A1 IL17D IL1RAP APBA1 TUBB3 RDH12 ADORA2A CD80 PPM1J SLCO5A1 SCUBE3 FCAR WDR82 FTSJ1 TIMM21 SLC31A1 USB1 UCHL1 NPC1 DPP9 TBP TFEB SPRYD3 SEC22B BAK1 MOB3A SP140 TMEM43 AIG1 CDC42BPB CMTM7 CLPTM1 ABHD12 ABHD5 C5ORF15 URGCP PARM1 FLCN FAM108B1 SLC35C1 MTA3 TIGD7 NUP62CL KLHL21 MEF2D KCTD7 VPS18 EML5 RABEP2 CAPN10 TET3 MFSD12 DBNDD1 DAPP1 STRN4 NFKBID C19ORF48 SSH1 STARD3 LRRC32 SLC25A44 DHX33 NRF1 TMEM189 SLC31A2 DTX2 PPARA DGKG VAMP2 CD320 ECE1 TGFA LRRN1 KDM4A LPP HID1 ARHGAP32 TSC2 PDGFB MEN1 CBX7 ATP2A3 KAT2A DHPS UBR4 CD79A ATG9B SNX13 ZNF383 GOLGA5 SLC5A6 FMO5 TGIF1 NFYA GPSM1 HDAC10 PATZ1 PPWD1 ZC3HC1 UTP15 PPIL4 POLD3 GRWD1 HRK SUPT3H ATF1 SLBP FITM2 KANSL3 GMEB2 IP6K1 ARID3B TNKS2 TTPAL TMEM55B ZSWIM4 GSE1 IL17RB SFXN2 RBM14 FAM173B RHOF ZP3 MFAP3 TECR ZNF672 C19ORF47 FOXRED1 ADAT3 CAMSAP2 CDR2 ZNF592 ZNF778 MON2 LCOR DESI1 SEMA4F FBXO38 TJAP1 RBM10 RGMB HECW2 AHDC1 SSPN CBX6 ZNF264 TBPL1 TMEM38B APPL2 FCRL1 GDI1 SBF1 VAV2 ICOSLG EZH1 HIC2 PIGX SLC12A4 CENPJ OSBPL11 KIF1B MDFIC ZC3H3 KRTCAP3 RALGPS1 C6ORF136 ZNF766 MCM8 PKNOX1 STRIP1 EIF4A3 RNF38 CADM1 MAU2 PHF2 RNF217 GPR180 TIGD3 SLC35E1 COQ7 GNG7 PPP1R12B SCML1 ATN1 SPATA2L MLL4 CCDC64 LMBRD1 HIAT1 MR1 CTDNEP1 MAPK1IP1L POLR3F ZNF611 KLHL25 ABLIM2 ROM1 CCR10 TCEA3 TMOD2 PQLC2 OXNAD1 MBOAT4 RTEL1 AMER1 MRPL49 ARL16 EDARADD ZNF786 FKRP ZNF343 CTU1 CNR2 PAK3 ADCK2 CDK3 DNAJC14 CTTNBP2NL TTLL11 ZNF329 FSD1L STXBP4 BAG2 GJA9 GDPGP1 FTSJD2 RNF220 DNASE1L2 CEP57L1 JMJD7 FAM65A MAN2A2 TMEM234 STAMBPL1 RFX8 FAM221A TSPYL5 FUK PDE7B PNMA1 RSPH3 PNOC PHF15 AIRE LACE1 PEX11B KCP PHF20 SYNDIG1 C1ORF216 C16ORF80 PCIF1 CYBASC3 PPT2 CCDC90A DSCR3 MAMU-DOA THAP8 C17ORF72 ZFYVE27 CBFA2T2 PPAPDC2 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MYH9 SLC36A1 UBB SPTB BCL2L1 NIN SEC14L1 STAT3 UBXN6 EPB41 MYO1D PKM NBR1 TUBA8 UBA1 JAK2 SPTA1 AP2M1 POLA1 GPX1 CRISP3 BAIAP2L2 PSMD4 HBQ1 GIGYF2 PKLR MARK3 TST ST3GAL4 TUBA4A SDE2 BAG6 SIRT5 PXN PRKAR2B BRD4 NUP98 STOM DIAPH1 GSK3B HBM LNPEP MX1 CHD1 PTK2 SLC25A39 ARHGEF12 BRI3 KLF1 TLN1 GBE1 RILP CD55 FN3K RWDD3 CPT1A FECH STXBP2 BEND7 RGS2 IFI27 REPS2 NCKAP1 TET2 SCIN SLC2A1 HIST1H2BD DHRS9 ARID5B SRRT PNPLA2 LGALS3BP THBS1 GRINA PTK2B USP19 BSDC1 ITGAL HK1 ITGAM ITGA5 DDB1 C1ORF43 NAIP CTSB CREG1 SLC16A1 E2F2 RAB13 ITSN1 CLEC1B TEX2 MICU1 TOPORS CXCR2 TCN1 PHOSPHO1 NOTCH1 RMND5A ELANE ASB7 CTSG LTF USP32 PPP1R13L SLC7A5 ZNF217 CLU INPP5D GABARAPL1 MAP2K3 SORL1 STK40 MED25 TECPR2 RERE CREBBP ZFAND3 TAB3 CUX1 ARHGAP27 RSAD2 GRAP2 OAS3 SLC29A3 GZMA IFIT1 TKTL1 HMGB2 VAV1 MYO1F TNNT2 MYL4 IFIT3 IFIT1B OAS2 XAF1 CMPK2 EVI2A XRCC3 SLC4A1 VCAN ADAR SAMD9L HSH2D SLC7A11 AIM1 PARP14 PLAU NAP1L5 ACER2 THBD TNS1 SELK EPAS1 MAP1LC3B PPP1CB CHMP4B DTX3L PLIN2 GLUL ARRDC3 DDX3X PTGR1 CSF1R CD97 S100A16 MYLK WNK1 FNDC3B SELENBP1 VWF RAB3GAP1 GLRX5 RAB5A SERINC3 GPX4 KDM6B PTGER3 DEFA3 C17ORF99 BPI OLFM4 TNFSF4 YOD1 BAMBI ZNFX1 FOXO3 BABAM1 WBP2 GYS1 GALNT7 GPR160 ZMAT2 SDC2 PAN3 CORO1C NOSIP STAU1 KIAA0430 MXI1 RLF GNA13 SOAT1 INTS6 NCOA4 PIP5K1B MKRN1 CKAP5 FOXO4 SRXN1 SNX9 FAM129A ATP5E TAP2 SLFN5 SMOX TRIM5 PDK4 C7ORF49 PRG2 TNFAIP8L1 NFE2 PRKD2 FBLN2 TESC AARS SLC51A CRISPLD2 HIST1H2BG AMFR SEC62 XRN1 SP100 MX2 HERC5 TRANK1 DDX60L SAMD9 GBP1 TOP1 NIPBL KDM5A CRKL ATRX CDK17 GMPR BAZ1A SLC28A3 FAM210B SP140L N4BP1 SMCHD1 VNN2 PHACTR4 PIK3AP1 CFLAR TM7SF2 BLVRB TCEB2 PRTN3 R3HDM4 MPO XPO1 ROCK1 PLEK CAST NAV1 GUCY1A3 CEP152 BTBD8 SWT1 DENND3 FRY IL1RAP SEC14L2 SEMA7A ADAM19 PLXNB3 RNF144A C7ORF61 TLR8 PRDX2 PSMD9 CD93 IFNLR1 RIOK3 NADK CLPX BSG FAM111A NEDD4 RAB5B SNX6 UBALD2 NECAP2 CALCOCO2 WIPI1 PPM1A TPM1 ALAD AKIRIN2 C6ORF62 C11ORF71 MPST ABHD4 XRCC2 GPCPD1 ARHGAP24 ACSL4 PINK1 TEP1 CCDC17 EEPD1 POLR2A IQGAP1 ACSL1 BCL6 NEXN YPEL3 SSH2 KCTD20 MYO9B TAF1 KANK2 RBM6 MFN2 HIPK2 FAM214B ANKRD17 PC NPL ROCK2 IGF2R SP1 NPEPPS FXN NCOR1 NCOA2 JMJD1C NF1 CBL BACE2 ZCCHC6 BCL2L11 FIS1 AMBRA1 WDFY3 TLR5 HIST1H2BJ MKNK1 UBR2 APAF1 DEFB1 BCL2L13 PLD1 ALDH1L1 PSMF1 GBF1 RALGAPB FBXO11 SLC18A2 HP1BP3 EPOR TACC1 RBM38 IFRD2 ZNF24 DOCK2 PRDX6 TMOD1 PLCG2 SLC25A20 JOSD2 BRCC3 USP24 ITSN2 ABTB2 GSE1 SLC25A37 CSGALNACT1 NFIX SULF2 TMEM131 IGF2BP2 KDM5B RNF40 ARHGAP21 DMXL2 RC3H2 PHACTR2 HIPK1 LIMK2 A4GALT DCAF11 RNF103 BAZ2B UBE2O BRAP EVI5 DOCK5 MED12L CPEB4 EIF4G3 ZC3H13 SLC41A2 HDAC11 KIF5B TRIP12 PRKCB WDR26 RNF10 AP2B1 MSL1 SMPDL3B DOCK4 PLCL2 CCNDBP1 DCAF12 SPRTN UBALD1 C3ORF62 ARHGAP26 ITPR2 ASCC2 RUFY1 BRWD3 CLK3 KIAA1109 SPECC1 SMAP1 PSME4 UBAC1 ISCA1 FAM46C TCEB3 EPB42 MPP1 AFF1 STRADB OSBPL8 PTOV1 DGCR14 ADNP DNAJC13 KIAA0368 CHERP SLC18B1 TSSK3 TMF1 SLC43A1 HELQ METTL20 MED12 COG7 MED28 PGA4 ZNF236 DHX8 NCOA6 ARFGEF1 ZBTB49 DENND2C PAK3 PAPOLG XK RSPH9 GNPTAB CLASP1 C7ORF41 C17ORF103 LRRC6 PHF8 DACH1 ZER1 CRAMP1L UBE3C PLAC4 C10ORF118 WDR59 TMEM255A GPR97 APOBEC3H RNF175 FAM21C TRIM58 WDR45 STK16 PPP2R5B DEFA1 HYAL3 EPB49 PRG3 MARCH8 C10ORF116 EIF2C2 LEPRE1 CHRNA10 MARCH6 C10ORF12 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in PBMCs at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 DCTPP1 SUMO3 EIF3F PBLD NUDT2 PFAS CISD3 PDZD11 YIF1A KHK GTF2F2 TPRN SEPSECS SIGMAR1 USP13 FAM109A FBL BZW2 FASLG NUTF2 ITM2A RCC1 ZNF575 EXOSC5 CCDC86 PTPN4 THTPA GGH GFER ABHD14A MDH1 RABEPK MRPL9 KLF12 TASP1 PROZ GSTZ1 OSGEPL1 C20ORF27 RPS26 CDK2AP1 METTL23 RPS8 SLC25A4 WDR63 SSBP2 RPS13 TC2N CHCHD10 PRNP ZC3H7B SNRPB VASH1 SUMF2 URM1 TMED9 RHBDD2 NDUFB5 ALDH1L2 MRPL12 TUBG1 NLN TMTC2 LGALS1 COMMD9 PRDX1 HSD17B10 NETO2 COX5A CD247 KLRG1 MATK RUNX3 ARVCF CEP78 ZNF540 CGREF1 MUTYH HINT2 PIK3IP1 CISH MINPP1 SCRIB SLC2A4RG EPS8L1 SFRP4 AXIN2 MAF ASIP IPO9 WWOX DVL1 ELP4 CD6 CD3G SKAP1 SEPT1 CAMK4 DUSP2 GFI1 CD27 HCST CD3D THEMIS ARHGEF39 TRAIP CD3E GPR171 TMEM143 HAS3 TNFRSF12A GLT8D2 RPL28 RAMP2 TMEM204 C9ORF69 SLC16A11 NR1D2 ARL6IP4 TMEM160 QDPR BNIP3 SH3PXD2A FDX1 KRTCAP2 TRMT112 ERRFI1 RBM3 PCOLCE MARCKSL1 RFTN1 NDUFC2 SEC61G SSR3 BEX4 DUSP8 TRAF1 ADAMTS10 SOCS2 ANO8 TMEM120B MAFF FOSB TMEM258 ATRAID ISCA2 CMSS1 C19ORF70 NDUFAB1 CUTA SRM POLD2 DCXR PRDX4 AP1S1 L3HYPDH UBE2E2 COPRS C19ORF10 NOP58 MRPS35 MANBAL PHLDA3 EMG1 NIF3L1 NDUFA12 PIGP ZNF593 NIT2 PSMD14 SPCS1 CMC1 GTF3C6 NDUFA9 YAE1D1 EXTL2 TOMM5 DDB2 SDF2L1 TACR2 TOB1 MRPS6 POLR1C CREB3L4 SURF2 VEGFB ZDHHC15 CINP SIK1 F10 ATP5G2 SLIRP NUP43 EBI3 NOXA1 ALG9 RHOH GCAT FAM185A HIST1H4E LRRC42 PIGL AFAP1L2 ZNF791 NAA40 DCTD EOGT CCDC106 FASTKD3 C17ORF67 EIF2B4 THNSL1 TMEM238 MTX1 KLRF1 GAS1 RALGDS DNM1 APBA1 PFDN1 POLR2H TIMM21 UBL4A COPS3 USB1 UBA2 PPIE CAMSAP1 PRMT1 BACE1 TBP TXN2 PARS2 ZIK1 FKBP14 FCF1 COQ4 ZNF569 ZNF34 AIG1 VSIG1 APRT CIRBP CA6 TIGD6 JMJD4 ZNF324 COMMD10 DCAF13 FAM118A FAM108B1 THBS3 RIOK1 NUP62CL NDOR1 FIZ1 BCAT2 SLC16A13 PEX10 HOXB6 ITPA EML5 FAM102A MVK MBD3 SLC37A4 TMEM129 PPP1R14B TIMM13 C19ORF48 SSH1 SIVA1 RSAD1 RBFOX2 AP1S3 DHX33 RPS6KA4 TMEM189 PPARA ACTN3 CD320 SLC2A12 FER1L5 ZBTB21 DYRK2 COPS8 TNFRSF10B ABCA3 ATG4D RAB26 ATG9B TTI1 TRIM52 TUBGCP5 ZNF621 SPICE1 ZNF383 ZNF398 ABCA5 AAAS PIGG SLC27A5 AEBP1 TGIF1 TRAF4 PEA15 PARP2 APBA2 ABI2 MGMT PATZ1 IL11RA GLS2 TIMM50 RPP30 PRDM4 TSEN15 MRPL4 RPUSD1 MLLT1 WDR70 SUPT3H MAP3K10 CRTAP DUSP12 TEX264 DBNDD2 FITM2 C6ORF48 ZNF550 ZNF140 CAPS NSDHL PCYT2 TMEM141 STXBP6 NTHL1 GAMT CHCHD6 PGAP3 NDUFB8 PXMP4 KIF5C ADAT3 RAD54L2 CHML WDR18 NDUFS8 TMEM161A ZNF778 ATP5G1 RFXANK POLR3D NSA2 ADM5 NOP16 MRPL43 CBY1 ARSD DUSP23 PID1 ACAD8 SNX16 NTPCR PDK3 KCNMB1 DIMT1 LSM6 KRTCAP3 AES CLYBL CCL15 KIFAP3 ZNF766 MCM8 CNNM2 MARCH9 SLC35B2 SLC25A12 TXNDC15 ST7 CD3EAP RASSF7 C14ORF142 RORA FBXW4 POFUT2 TIGD3 CNIH ZNF260 LYRM7 C16ORF52 FAM73A FLYWCH1 DUS1L ZNF358 C17ORF70 ATP5I MEIS3 POLR2I DNAJC30 FAM108C1 POLR3F MRPS17 TMEM242 HABP4 PTRH2 EFCAB2 SPIN3 SRRD PTRH1 SSBP4 FLYWCH2 ZNF181 ABLIM2 N6AMT1 TRIT1 RABL5 DIEXF QTRT1 FBXO44 GALT TMEM8B LIME1 PRSS56 MBOAT4 TMEM223 YRDC RTEL1 TOE1 TRMT61A B3GAT3 METTL12 ALKBH4 EDARADD CCDC150 HEMK1 CDK3 ZNF570 DTX3 ZNF329 DENND6B PPP2R2B IPPK KLHL32 ZNF69 BZRAP1 ADAL KCNG2 MORN4 BOD1 BOD1 INTS10 MIS12 MOCS2 C11ORF1 POLR3GL ANGEL1 ERI1 C10ORF35 ATRIP SLC25A43 ZSWIM7 C9ORF123 PGBD1 FUK PDE7B TMIGD2 KCNJ14 MNF1 PHF15 CEND1 LACE1 PEX11B KCP C1ORF216 OSGEP GGT7 C12ORF52 WDR35 C20ORF201 C19ORF60 CATSPERG C19ORF57 FGFBP2 UBE2D4 N6AMT2 WBSCR16 FAM203A SAMD3 C8ORF40 ZNF790 PYHIN1 FDXACB1 TFB2M B9D1 BRMS1L C12ORF61 SNAP47 C16ORF13 CHRNA9 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GNA11 FAM8A1 DNAJC11 PCK2 UPF1 CACNA1D GOLGA7 NEDD9 ADAM9 EHBP1 HMOX1 PLS1 PHB2 OAS1 COPB2 PTX3 STAT1 TRIM25 NARS2 USP48 NLRX1 OASL WFS1 AKAP9 CCL25 AKR7A3 GFER ERC1 ASCC1 ZFYVE20 FAHD1 UBOX5 ARHGAP18 PAIP1 SCYL1 NAE1 CHEK2 NT5DC2 STOX1 ENTPD3 FAM216B PPL LMO7 TSTD1 WDR63 LCN2 DHRS9 PLA2G15 TMC6 ADCY7 PARP10 DENND4B RNASEL ATG4B PTK2B TUBGCP6 KHNYN TYMP EFTUD2 ITGAM APOL2 HK3 PPP1R12C FBXO6 CD101 CLTCL1 NOL3 NUF2 ESPL1 GPNMB RRM2 PDSS1 KPTN EPSTI1 ROGDI LAMC1 KIF11 TPX2 CDC20 TRIP13 TTK FAM89A HP ESRP2 TPM2 RHEBL1 CRY1 CCL4 MUTYH ABCC5 MMP11 SNPH LTF TMC4 CCDC120 SLC52A2 ITPR3 ARHGEF16 SLC26A4 WDR7 BMP8A SPRY3 ATF3 MAP3K4 TMEM88 IQCE NBEAL2 AP5B1 HELZ2 MNT SBNO2 CDC25C IRF7 MTFR2 CHEK1 RAD51 GINS2 NLRC5 GFI1 CX3CR1 FCGR2B S100A9 CDH26 CDT1 LRP8 XAF1 CCR1 IL1RN TREX1 IFIT2 KDM4D HEPACAM2 CLEC4E MAB21L3 CD177 AKNAD1 IFI35 PARP14 TRIM6 TRAFD1 PPA1 PARP11 BAG1 UNC45B IRF9 RAPGEF2 ARRDC3 ZBTB16 BMS1 C1ORF198 METTL14 KIF26B RAB3GAP1 USHBP1 FPR2 CREB5 DEFA3 COL9A2 IL27 BPI TRIM22 SIGLEC9 S100A12 PGLYRP1 TLR6 DCUN1D3 SPON2 E2F6 ZNF841 TG SLC2A11 CITED4 TP53INP2 C1ORF233 SLC25A27 TOR4A LRRC10B BRD1 CDC42EP3 PFKFB3 CMSS1 CRYZ POLD2 HTATSF1 PNPT1 SNX10 SOAT1 GLB1 ZNF512 TRIM72 MGEA5 RIPK3 MRGBP DOK4 DIAPH3 DHRS13 IL1R1 ME2 ODF3B NSF APBA3 GSTCD STK32C SLFN5 IL15RA TRIM21 RNF31 ROR2 TRIM56 FAM46A WDR90 TRMT12 GCAT SLC6A4 ATP6V0D2 FAM185A CEACAM8 FNBP4 ISL2 ORM1 ABAT ARID4A LRRC45 APOBEC3B C19ORF66 SP100 ZNF461 PAQR8 CORO2A PJA1 PNISR KLHDC7B DUSP4 NAPA RHBDF2 TMEM62 PARP8 IL18R1 DYSF SRSF5 ZNF397 SIRT4 GRIN3A PIK3R3 ACTA2 EID3 SERPINB8 SRSF12 SEMA7A SDC3 DLL3 PLSCR1 SCRT2 ALPK3 FUT7 SIGLEC5 CD300A GK AQP9 UCHL1 APMAP IFITM10 TMEM165 COQ4 PI4K2B WDSUB1 ESYT3 KCNJ15 CCPG1 TINF2 RIN2 HIRA INPP5E KIN ANKMY2 GOLGA4 COMTD1 FBXW9 PAPLN TEP1 PRSS53 NUDT17 DDX39A ACSL1 BCL6 LILRA1 TENM1 RRP12 MYO9B S1PR2 SSH1 FAM219B ARFRP1 APEX2 PRSS8 GCK CHDH KEAP1 CLCN2 ZNF3 CDKN2A PLXNA1 TDRD6 KMT2C CYTH2 BHLHA15 TTC30A CHD2 ZCCHC6 PITPNM2 CYB5R2 DISC1 MAPK7 SPG11 SLC38A9 ADAMTSL4 VPS16 MKNK1 ARSA SCARF1 RAB24 ZNF720 ZBTB25 ZNF398 IL17RC CPT2 SLC2A14 RFX3 SUDS3 LAPTM4B LATS2 TOP3B DOCK8 H3F3B DNASE1L1 DNAJC17 CTDSPL FITM2 PFKFB4 FAM188B SH3RF2 ZBTB39 INO80 AEN ORAOV1 MED13L ABTB2 KBTBD2 EIF2B1 MIER3 UFL1 SLK VWA8 GPSM2 PHIP CRNKL1 THG1L CLDN12 HORMAD1 ZDBF2 QPCT SNX24 RAB39B NOC4L TAF6L SLC27A3 STAG1 DMXL2 DIDO1 NLE1 LHPP ARMCX5 C11ORF24 RBM10 KIAA0754 RPAP1 SLC41A1 ZNF594 MIA ZNF441 GRIP2 CBX6 GBA2 ANKS6 SLC25A17 GCDH SARDH PEX16 SIDT2 VPS33A ST6GALNAC4 MSTO1 BRSK1 DOCK4 CCNJL CNTLN PRDM10 CEP128 RAD18 ANKS1A SYNE3 COL5A3 ATP9B ARHGAP26 NKTR SCAPER IFT140 ALKBH2 EXOG PHF3 PTDSS2 NAT6 STK11IP PGS1 RIN1 UNK ULK4 C11ORF21 ZC4H2 FAR1 SLC2A13 ATN1 ITFG3 PIDD IQCD UBE3A C4ORF21 CCDC101 WHSC1 WDYHV1 DNAJC13 CCDC176 ZNF530 AKAP6 GHDC ENGASE ZNF777 SLC18B1 RAB42 CNTNAP1 ATXN7 C3ORF18 DENND1A DLGAP3 PGAM4 ZNF549 BUD13 TOE1 ARV1 METAP1D BTBD18 DHX8 ZNF500 PNMT PRICKLE4 D2HGDH NUDT13 MTM1 PHF14 ZNF490 ZNF329 PBX4 MDM1 KATNAL1 ZNF586 PCDHGB6 MFSD4 CUL7 AGK FBXO18 DACH1 ABRA ANKRD24 CERS4 DEF8 VWA3A POLR3GL RANBP3 FBXL2 ZSCAN5A SEC61A2 RNF175 FAM203A C7ORF10 IDI2 ZNF311 C1ORF172 C19ORF35 COPZ2 MON1B MEF2BNB-MEF2B ARIH2OS GNB5 C7ORF29 SLFN12 C14ORF79 C8ORF33 KTI12 CC2D2A PRR18 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBB UBL5 RPS27A BCL2L1 RAD23B RPL12 UBXN2A EPB41 SCCPDH ING5 GABARAPL2 BAG3 F5 RYBP FAM162A GPX1 POFUT1 TM4SF5 PDE4D GLOD5 ELK4 PES1 YWHAH AKAP8L OXSM SLC25A39 UBE2E1 SCRN3 LRRC8A CREBL2 WDR89 UFC1 RWDD3 DNAJC18 TLCD1 FECH C1ORF63 RPS20 DEDD2 PFDN5 RPS17 CXCL6 RPL41 RPS15A RPS24 GCNT3 TPT1 RPL38 RPS3A PAWR RPL30 RPL13A SLC2A1 RPSA GADD45A CKS2 RPS18 RPS29 NFIA RPLP1 RPL11 RPS14 RPS7 RPS27 RPL27A FTL GRINA FKBP8 HDAC6 ITGB5 TRIM65 CLUH LPL KCNK13 RNASE2 DDIT4 RAB13 HADHB CTSZ ADORA3 CALCRL SLFN11 DYNLL1 CENPW CDC45 MAP3K6 CCR3 NOG PTGS2 CEP78 TSPYL1 TRAT1 HINT1 RMND5A B4GALT7 TRAK2 MAPK8 JMJD6 ELMO3 COL17A1 TONSL SP6 WNT5A FGF9 DACT1 RAP1A CASP2 DYRK1B ZNF646 RGS1 CREG2 IL18BP KNTC1 GZMA TRAIP POLE DNASE1L3 ALOX15 ALAS2 PAQR9 TRIM10 C5ORF28 SNCA NPRL3 TLR3 HPCAL4 NAP1L5 TNS1 SELK RPL8 FOS PPP1CB EIF3G DUSP1 ADIPOR1 TXNIP NFKBIA GATA2 TSPAN7 JUN RPS23 CHCHD2 RPLP0 CYB5A COX7A2 BTG1 RPL22 COX8A ABRACL CCNI CETN2 TSC22D3 SEPW1 CHORDC1 HSPH1 AQP1 BLMH RBBP4 DNAJA1 DNAJB1 SELENBP1 EEF1G KIAA1462 RPS3 GLRX5 CHCHD1 GPX4 COX14 BNIP3L C10ORF128 PTGER3 C17ORF99 CR1 TMEM14B RIMS3 ZSCAN9 TNFAIP3 NTNG2 ZFP37 FILIP1L RTN4R PCBD2 SEC31B AMOTL2 CCRN4L DUSP5 KIAA0907 YOD1 PPRC1 OST4 NUP155 NR2C2AP SNRPG PDLIM1 BABAM1 CHCHD4 MRPS33 MTX2 PSMD10 UQCRQ WDR83OS PCBD1 PIGP MGLL AMD1 SLC10A3 ST13 ERH HEBP2 TOMM5 MXI1 CCDC117 TCP1 DNAJA4 USP10 PDE4B EXTL1 TMEM194A SRXN1 TAF7 TTLL13 MTFR1L C15ORF48 RND1 MKKS TRIAP1 GMDS TRA2B TIMD4 C4ORF45 DUSP28 GCHFR SLC13A4 TMEM40 CCDC15 HIST1H4E RP2 TMEM68 PIGL TSTD2 GYPC RECQL MBNL3 TMEM56 ZNF623 C3ORF80 PPIL1 BCL10 RBMX C1ORF174 KBTBD6 PIK3R1 POGK YTHDF3 PKIB GFPT1 PKHD1L1 PLK2 FBXW11 GMPR CPEB2 NFE2L3 FAM210B CSTB GNB2L1 SERF2 FBXO7 BLVRB TCEB2 SESN1 SLC25A42 NRL ITLN1 SLC16A10 RDH12 FCER1A AKAP7 CCSER1 TAL1 PRDX2 RNF135 GATA1 PSMD9 THUMPD1 MRAS BSG TXNL1 EIF3D GDE1 TP53RK FCF1 RNF34 TMEM183A YIPF4 CMAS CDK5RAP3 AVPI1 ABHD5 MID1IP1 RPGR ZNF8 ANKH MZT2B EIF1B JAK3 NFKBID ATP6V0A2 RHBDF1 KANK2 C6ORF106 PLN SLC5A3 ZBTB14 ZBED5 TRMT1L NDUFAF6 PIAS4 BACE2 PDGFB EMC6 PLD1 ZSCAN32 ZNF284 GTPBP1 ZRANB1 SLC27A5 TGIF1 EYA3 EPOR DFFB PRPF38A TTC9C REXO4 UTP15 RWDD1 GTF3C5 HN1L HRK PRDX6 IREB2 TMOD1 SFXN1 JOSD2 NUDT21 SLC39A6 ANAPC16 IARS2 TOMM7 OSBP MTMR9 RUSC2 UBE2E3 FAM173B ELP6 KCTD11 NFIX ARHGEF6 DCUN1D1 DTD2 PARD6G RSL24D1 TOM1L1 BTF3L4 ZMIZ1 CAMSAP2 USP38 HIPK1 OPHN1 SPTY2D1 PIP4K2A NMD3 C14ORF2 TOMM6 KLHL28 ZNF654 GPR135 DTWD2 MRPS14 NOP16 TGIF2 BLOC1S5 HDAC11 EHD3 RNF10 ZNF121 ZNF79 IKZF5 ZNF92 LYSMD3 C5ORF51 ZRSR2 HIC2 DCAF12 PCMTD1 C18ORF54 PHAX UBALD1 C2ORF88 C9ORF40 ALG2 PDP2 ASCC2 ARHGAP39 FAM220A RHAG SPECC1 WDR61 ISCA1 FAM46C NUDT4 STRADB TMEM106C TIGD3 C7ORF73 MOB1B ZDHHC21 POMGNT1 PPP2R5E SCYL2 IL8 FTSJD1 POC1B TMEM184C KDELR3 NCBP2 MRRF MTMR4 TESK1 HTR7 MMRN1 RAB39A DIEXF SLC43A1 AAED1 EPM2A TUBB2B THBS4 FAM175B BCDIN3D TTC24 PTCD1 TAMM41 PGA4 CCNK SLC25A19 TMEM216 DPH1 CNOT7 ZFP62 TMEM81 BNIPL ZNF689 PCDHGA6 ZNF347 AK7 SPIN2B C5ORF4 TMEM39A CCDC136 WNK3 ATXN7L3B ASPRV1 GFRA2 POLR1D TRERF1 PEX11A ST7L ZNF214 NFASC KIAA0355 ZNF547 C13ORF35 GKAP1 KRIT1 NFYC COG1 PAFAH1B2 KCTD21 TRIM58 HYAL3 DCLRE1B ICAM4 TEAD2 ABHD1 TMEM180 OLIG2 EPX FAM58A GAREML PRMT10 TMEM5 GTDC2 C20ORF196 C17ORF75 C12ORF5 FLJ44635 DARC ZNF517 METTL6 ALKBH1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FGL2 ABCC1 CD200R1L NMI KPNB1 PCK2 DDX58 VHL CXCL10 RIPK1 CACNA1D IFITM1 CDHR5 LAP3 JAK2 HOOK3 MPZL1 HMOX1 RBCK1 OAS1 PTX3 GRIPAP1 MYO7B BIRC2 ST3GAL4 UBQLNL STAT1 TRIM25 NARS2 CNDP2 EIF2AK2 POR CHRNB1 APOBEC3G OASL MOV10 ISG15 SRC NUB1 MX1 CHD1 SIPA1L1 KMO ACO1 SERPING1 MT2A TNFSF10 KLF5 IFI27 EXT1 FAM216B S100P SMPDL3A PEAK1 MTRNR2L1 APOBEC3A SCIN RGL1 CD300E CCL8 ISG20 DHRS9 UNC93B1 PARP10 LGALS3BP TOR1B ARHGEF10L TOR3A C1QA PTK2B KHNYN TYMP BST2 EHBP1L1 SLC15A3 HK1 APOL2 LTBR FBXO6 MILR1 VSIG10L LMO2 C3AR1 SCARB2 GLRX LDLR TMEM106A NOL3 IFI44 ADAP2 NUDT16 ESPL1 IRF5 SCIMP KPTN EPSTI1 ROGDI HEBP1 C2 EPHB2 EPS8 BATF2 FAM89A HP SPATS2L LIPA DTL SPTLC2 NKIRAS2 SLC43A3 RASGEF1B CDKN1A ABCC4 AGRN TMEM60 INPP5D ATF3 ELF4 MEF2A MS4A6E FCN1 AP5B1 RERE TNK2 HELZ2 OGFR SLFN13 RSAD2 OAS3 IDO1 IRF7 ZBP1 BARD1 NLRC5 TAP1 GPR84 IFIT1 FCGR2B NDC80 CCL3L3 IFIT3 RTP4 IFIT1B TLR7 OAS2 PHF11 SIGLEC1 XAF1 PSMB8 CD274 APOL6 CCR1 DHX58 CYBB IL1RN TREX1 USP18 CMPK2 IFIT2 IFI16 PLAC8 HERC6 IFIH1 TNFAIP6 STAT2 PML ADAR GBP2 PARP9 PARP12 SAMD9L GCH1 HSH2D NFIL3 CASP4 AIM1 IFI35 PARP14 SOCS1 TRIM6 TRAFD1 SAMHD1 CSTA PPA1 PARP11 UBE2L6 DRD4 UBA7 SP110 DPYSL2 TFG EHD4 PSME2 KLF4 LY6E IGFBP4 PSMB10 BAG1 DTX3L IRF9 GBP3 FABP5 GNG10 IFI44L DRAP1 RNF114 DDX3X GIMAP4 FHAD1 GM2A NUCKS1 RAB3GAP1 CD164 DEK CECR6 IL27 CSF1 TRIM22 C21ORF91 DCUN1D3 ZNF267 PLA2G4C PAPD7 CSRNP1 ZNFX1 MRPL24 CHMP5 LSM2 DYNLT1 LYSMD2 TNFRSF21 MCEE PRPF3 PNPT1 TMEM50A SNX10 MAD2L2 RPS6KC1 GPBP1 PAPD5 APOBEC3C SAMD4A RIPK3 MED10 GLCE GNB4 ME2 ODF3B SHROOM4 VAMP5 P2RY14 VRK2 SLFN5 CASP1 PPM1K IL15RA ZCCHC2 ETV6 LGALS8 TRIM21 MOCOS GSDMD USP25 TRIM56 FAM46A ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 PCGF5 RIPK2 IL15 AZI2 ANKFY1 BATF3 RAB44 IFI6 DDX60 DMAP1 C9ORF91 APOBEC3B LIG1 DNAJC7 RNF19B C19ORF66 TNFSF13B XRN1 SP100 RARRES3 MX2 IFIT5 HERC5 TRANK1 DDX60L SAMD9 GBP1 SLC47A1 WSB2 KIF1A PAQR8 CORO2A PKIB HES4 KLHDC7B CDK17 ETV7 MICB BAZ1A PMAIP1 TICAM1 PATL1 NAPA ERAP2 SP140L MDK RHBDF2 N4BP1 SMCHD1 TMEM62 MOB3C CHSY1 TRIM38 FAS RABGAP1L FMR1 PIK3AP1 CFLAR GTPBP2 TRIM26 RAB8B DYSF AZU1 XPO1 SRSF11 ARHGEF3 ARMCX1 P2RY6 OSGIN1 SDC3 PLSCR1 HRASLS2 CD68 NCOA7 PPM1J PDE1B CCL22 SEMA4D TANK IDI1 NAGK SIGLEC5 CD300A SCO2 SIGLEC14 CARD16 BCL2L14 CASP5 FAM111A ERP29 SNX6 EXOC2 BAK1 TMEM165 PI4K2B STX12 LRRK1 CITED2 ALDH3A2 CD33 ALDH3B1 CTNNBL1 KIF13A RIN2 HIRA RBBP6 NT5C2 ACSL4 PON2 TMEM123 ANKMY2 PPP2R2A PODXL SYNE2 ATP13A1 PIM2 TFEC DAPP1 ALPK1 CCDC71L SLC38A5 GLS PELI3 ROCK2 PRKCE SP1 DNPEP ABI3 STK38L GANC TXNRD1 SRGAP2 MAP3K5 DISC1 GPC1 STX17 KAT2A ADAMTSL4 MKNK1 FPR3 MRPL40 DEFB1 VCPIP1 IL17RC SMU1 SLCO4C1 OR52H1 FUBP1 TWIST2 NUP205 CYSLTR1 H3F3B MSRA USP42 SIK3 SEC24D BAHCC1 TTC39B DIP2B DPY19L4 TROVE2 SBF2 CNP TMEM53 ELF1 PHACTR2 CCDC82 PDE8A CPEB3 DCLRE1C ATL3 DOCK7 FANCL ST3GAL2 NT5C3 ZNF281 IRF2BP2 DOCK4 RNF138 C4ORF33 CNTLN KCNMB1 DES ARHGAP26 SCAPER ZDHHC14 MPP1 CHD7 CADM1 ERO1L AFF1 MED17 FAM53C CABP5 ASPHD2 IQSEC2 OSGIN2 HIAT1 MR1 KIAA0368 MICALL2 DLGAP4 SLC18B1 RCBTB1 ATXN7 FBXO44 DENND1A CHRNB2 PGAM4 MAD2L1BP CTRL CBWD3 PAK3 MTM1 RSPH9 SMTNL1 FTSJD2 C14ORF159 FAM76A SCLT1 TMEM255A ABHD6 PARP15 APOBEC3H CEBPE SLFN12 C9ORF89 OR52B6 TMEM110 DIAPH2 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 ANO9 UIMC1 CCL5 MOGS HIST1H1C UBXN2A MME RBL2 ZZEF1 FURIN FBLN5 FAR2 TUBA1A RYBP MPZL3 TMEM39B PDE4D SRPK2 HERPUD1 PRKAR2A CD244 FBP1 SLC44A2 GGH LRRC8A CREBL2 PITPNC1 MPP7 PTTG1IP SLC25A16 RWDD3 RNF167 ADK EIF4B VKORC1 TMEM71 CXCL6 KRT18 RGS2 HIST1H2BC ALMS1 MXRA7 HIST1H4I SYTL2 HOPX RPL38 CA8 PAWR TRIM2 TCP11L2 STEAP4 RPL13A FAM214A SLC16A7 CYBRD1 FNBP1L RPS18 TPST1 TC2N RPL27A STMN1 DHRS7 PLCB2 LMNA HCAR2 RHOB TICRR DDIT4 TEX2 CCR3 CORO6 GPR68 NCR3 PLEKHA1 IL7R KLRB1 SLC25A29 ZNF830 MATK PTGS2 COL18A1 ARVCF PRDM8 NTRK1 YPEL1 SPON1 ZNF540 PRSS57 FCRL6 TGFBR3 PHOSPHO1 GADD45G BAD PIK3IP1 TGFBR1 SNPH WIF1 SP6 DACT1 NUCB2 PSRC1 ETV2 SORL1 PHF12 ST6GALNAC2 SYTL1 ZNF862 ULK1 GNG2 CREG2 SKAP1 CAMK4 GZMA TKTL1 TRAIP CD96 GPR15 LY9 GLIPR1 GZMK POLE DNASE1L3 CA3 CD84 CTSK IL1R2 CLEC4E PTAFR LRRC4 SLC7A11 BASP1 GAL3ST4 NAP1L5 TNS1 FOS SGK1 GRASP EIF3G ELOVL5 ADIPOR1 EEF2 TMEM204 JUN BTG1 SERPINE2 TP53INP1 PEX6 RGCC STUB1 TRMT112 CDIPT PRPSAP1 EEF1G RPS3 IVNS1ABP TNNI2 RFTN1 HIGD2A C10ORF128 IL16 BPI GPRIN3 LRRC70 S100A3 MAGEH1 FBXL16 BBC3 IRS2 DEPDC7 PDLIM1 MMP10 CHCHD4 HMGB1 CDC7 AMD1 FAM107B HOXB7 CXXC5 DHX40 HEBP2 SPSB3 MXI1 AGPAT9 DNAJA4 ADORA2B MRPS6 PARD6A C15ORF48 COL11A1 CD46 FANCG IL1R1 ITPRIP ZNF671 MAP3K14 SPATA7 FAM57A RASD1 NOXA1 CCDC153 TSPAN32 SPNS3 DGAT2 IL27RA FAIM3 CDC42BPG HIST1H4E CASS4 PELI2 CEACAM8 CD1B ORM1 CCDC28A KBTBD7 GMCL1 CHAC2 FOXD1 KCTD12 GLIS3 CNNM3 IGF1R CETP ACOT7 FAM110C HERC1 SLC28A3 RRAGD ANP32B B3GALNT1 BRI3BP TCEB2 S1PR1 LTB GPR56 HEXIM2 SESN1 BANP DENND3 RALGDS SESN2 CHST2 BCAR3 XYLT1 BACH2 NEK6 ITLN1 DPEP2 IL1RL1 FAM101B TMSB15B FCER1A LPPR2 SH2D6 RNF125 BDKRB2 RNF113A PET100 SENP3 TBXAS1 KIT EGLN1 WIPI2 MLLT3 CTSF ATG9A TARSL2 SMPD2 SPP1 GALNT1 VSIG1 ABHD12 ABHD5 PIGH TMEM177 TPCN1 STRA13 ATP7A FAM118A ZNF8 KRT222 TMCC1 DMPK KCTD7 MZT2B CYB5RL CLTB PLK3 HDAC5 APC2 CYB561D1 DBNDD1 OLIG1 PROK2 ZSCAN18 GNL1 RAF1 GLT8D1 VPS37B WBP1L HEXIM1 PDE3B CEP72 PPARA SLC5A3 ZBED4 CELA2A USP28 CDK19 WNK2 PIK3CB CCNG2 CBX7 IFT57 AK9 ATP2A3 ORMDL1 SLC19A1 CAMK2G ATG13 PRR5L FBXW7 GOLPH3L ATG9B ZNF175 CD300LB FAM167B S1PR4 CLEC9A PHKA2 SAMD8 ZRANB1 SLC27A5 TGIF1 MYB EYA3 SOX4 TACC1 PRPF38A GTF3C5 HRK ENDOG OGFRL1 LIPN CYB5R1 SLC39A6 SLC4A7 FAM179B ZNF335 ZBTB48 MOK KIF21B CLK4 PAGR1 CENPT H2AFV ZNF395 PTAR1 CPD SULF2 ZNF608 CEP120 APBB2 QPCT BTF3L4 PDK2 ZNF771 FAM222A EFCAB12 DSTYK DNAAF2 LEMD3 OPHN1 CLIP1 MACROD1 HTRA2 PRR7 PPP1R3F CNST RNF103 TP53I13 INTS12 NSA2 GPR135 HECW2 SLC25A51 PPP1R2 APBB1 BCAP29 TCTN1 HIST1H2AB GRAP WDR26 CHIC2 TCTE3 ZNF555 HIC2 TNPO1 FMNL3 KLHL2 AGPAT1 PDK3 UBALD1 COL15A1 ADARB1 TMEM120A SNAP23 PDP2 PWWP2A APBB3 ARHGAP39 FAM63B HSD11B1L MAGEF1 ZNF615 SLMAP ANKRD2 RORA GLTSCR2 TIGD3 SLC35E1 GPR27 PHACTR1 PPP1R12B RPRD1A GPC2 PTOV1 KATNBL1 IL8 KLHL22 DDX11 DIRC2 LMBR1 SF3B14 EFCAB2 CDKL2 ROM1 AK5 MAP3K15 SPATA6L DIEXF TMEM175 NEIL1 CCBL1 S100A1 SAP25 POLR2D PPP1R35 TTC24 MUC12 ZNF853 TMEM216 CCDC125 PLEKHM3 DCAF8 KCNAB3 FBXO46 FOXD2 TMEM81 BNIPL HOMER3 ZNF843 CNR2 SNTB2 LSM11 NGRN ZNF141 NMNAT3 BAIAP3 NT5M TMEM39A KAZN ELMOD3 CDH23 TMEM25 OSBPL2 CAMK1D TMEM66 KIAA0226L NFASC EMR3 B3GALTL PDE6H KLHDC5 FUZ ROPN1L WDFY2 DUS2L KCTD21 CCDC36 KCNJ14 C16ORF80 PPT2 GRAMD3 FCRLB CXORF57 FAM159A FAM211B CHRNG TAS1R3 CENPBD1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GCC2 SARS2 TMPRSS2 DNAJC11 PCK2 DDX58 DPEP1 CXCL10 CACNA1D PLA2G2D IFITM1 SEPP1 SLC22A18 ERG HMOX1 SERPINE1 BAIAP2L2 OAS1 MYO7B UBQLNL STAT1 TRIM25 NARS2 EIF2AK2 RETSAT ALG8 RARS OASL MOV10 ISG15 ACADS STAT6 MX1 UMODL1 FAHD1 PEX1 ZFAND1 NAGLU DDAH2 CHEK2 MNAT1 MYO10 TNFSF10 RGS2 IFI27 ERBB3 FAM216B ECM1 SMPDL3A APOBEC3A WDR63 RGL1 CD300E ISG20 PLA2G15 ATP10A UNC93B1 STMN1 ADCY7 PARP10 GPR107 LGALS3BP TOR1B THBS1 RNASEL SLC3A2 EMILIN2 TYMP CORO1B BST2 ITGAL HK1 APOL2 LTBR FBXO6 ERAL1 TK1 C3AR1 UBE2C LPL GLRX TMEM106A NUF2 IFI44 SEC23B SPAG5 MCM2 ASPM FH ESPL1 GPNMB CDK1 SMAD1 CDC6 E2F1 KIFC1 SCIMP EPSTI1 H1F0 UAP1L1 RRAS CDCA2 C2 EPHB2 KIF11 TPX2 NAGA CBR1 EPS8 BATF2 CDC20 SKA1 PSMB2 SPATS2L KIF20A DTL KCNMA1 RASGEF1B TYMS ESRP2 RHEBL1 G0S2 S1PR5 DZANK1 CDKN1A MMP11 AXL AGRN WDR7 TMEM60 PORCN GABARAPL1 PRC1 CTSC IQCE FCN1 TNK2 HELZ2 OGFR DDR1 RSAD2 CDC25C OAS3 IRF7 KIAA1524 NKG7 ESCO2 ZBP1 RAD51 SLAMF7 GINS2 GIMAP7 TAP1 FAM83D GFI1 SPC24 GZMA CX3CR1 IFIT1 RACGAP1 SLAMF9 POLE RAD51AP1 IFIT3 IFIT1B CDT1 TLR7 OAS2 SIGLEC1 XAF1 CD274 APOL6 CCR1 GINS1 DHX58 FBXO39 TREX1 CHAF1A USP18 CMPK2 IFIT2 IFI16 PLAC8 HERC6 TNFAIP6 STAT2 PML SOCS3 PARP9 PARP12 GCH1 ADM IFI35 PARP14 TRIM6 TRAFD1 GPR35 PARP11 UBE2L6 WARS THBD LY6E EPAS1 SGK1 IRF9 PXDC1 GBP3 VIMP IFI44L ARRDC3 CA4 ZBTB16 BMS1 GIMAP4 CTU2 COL9A2 DDIT3 IL27 HSPA6 PPP1R15A CSF1 PLA2G4C FUS SLC2A11 GIMAP2 ATRAID CYB561D2 SEC61A1 SLC29A1 LSM2 VMP1 SLC25A15 MFSD5 TNFRSF21 SNRPA RPS6KC1 SOAT1 ODC1 E2F7 APOBEC3C COMP SAMD4A ZNF618 RIPK3 DIAPH3 ATAD2 ODF3B SHROOM4 ABL2 VAMP5 TAP2 GSTCD PIGT NAGPA STK32C DNASE2 SLFN5 TLR2 IL15RA ZCCHC2 TRIM21 MOCOS ROR2 FAM46A TRIM14 PCGF5 IL15 TRMT12 IRAK2 RAB44 FAM185A ATP1A3 AARS IFI6 MCM4 DDX60 DMAP1 GTF2H3 LRRC45 APOBEC3B LIG1 NCAPD3 C19ORF66 SP100 RARRES3 MX2 IFIT5 HERC5 TRANK1 DDX60L GBP1 KIF3B GLG1 CCDC42B HES4 KLHDC7B SIDT1 ETV7 MICB PMM1 NAPA SP140L MDK RHBDF2 MOB3C BTN3A2 AZU1 MPO XPO1 GZMB SRSF5 GPR56 ARHGEF3 GUCY1A3 ARMCX1 PHLDA2 FAM115C SDC3 CXCL12 CORIN CCL22 ORMDL3 TRIM32 SCFD1 IDI1 SCO2 BCL2L14 GTF3C3 GBA XPNPEP1 IFITM10 BAK1 GPN2 STX18 PI4K2B ZNF330 CREB3 ASAH1 TMEM209 RIN2 HIRA MED24 USP8 PON2 TMEM123 PGPEP1 VPS18 NUDT17 LSS AMDHD2 PCDHGC3 TPP1 MADD SLC38A5 ACP2 SASH1 POLR3A APEX2 TMEM189 RNF123 PELI3 PLIN3 PRCP PRKCE KLF8 ABI3 CLCN2 ZNF3 PRMT5 PLXNA1 PTPN11 ACACA GPC1 KAT2A SLC26A11 RORC DEFB1 ABCA5 BTN2A2 IL17RC GBF1 CYP51A1 TUBB1 ABCA6 GSTM4 NIPAL1 WSB1 PARP2 NUP188 TOP3B DHDH FITM2 MAGED2 SH3RF2 C7ORF50 UFL1 DPY19L4 MTSS1L GPSM2 HEG1 DENND4C TROVE2 HYAL2 CNP NOC4L GFOD1 PHACTR2 EMB TMEM161A DCAF11 ZZZ3 ARMCX5 SLC41A1 FRS3 EXOSC9 ZNF441 HOOK2 DOCK7 ZHX3 VWA5A VPS33A IDUA DES NCDN SORBS1 SCAPER ZNF622 FTSJ3 EXOG ST7 EIF2B2 POLR1B ZNF155 CTPS2 IMMT ZDHHC16 ITFG3 IQCD ADCK4 IQSEC2 KIAA1984 C4ORF21 MR1 KIAA0368 GHDC ENGASE SLC18B1 RAB42 DOK6 ACRBP OGFOD2 GALT EPHX3 RUSC1 BUD13 VPRBP ELMO2 ARV1 DHX8 RRP8 ARHGAP33 ZNF420 NUDT18 GPAT2 L3MBTL2 FSD1L FTSJD2 FAM63A ARMC9 CUL7 PDE8B C14ORF159 LRRC29 HSPA12B ANKRD24 PHYHD1 CCHCR1 GUCY1B3 WDR25 CCDC28B TMEM255A APOBEC3H GGT5 TMIGD2 ZNF792 FGFBP2 IDI2 EPX C9ORF89 NMUR1 C14ORF169 PTPLAD2 GTPBP3 LNP1 MAMU-F L2HGDH SPATA5L1 FAM115A RNF214 ZDHHC4 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SPTB UIMC1 IL1B BCL2L1 ATP13A3 STX3 CSDE1 HIST1H1C MME ARRB2 CEP135 FURIN FAR2 NLRP6 UBTD1 TMEM54 UBA52 TMEM39B ATP1B1 MGAM SLC23A1 ING3 BDKRB1 FBP1 ICAM3 PTK2 CABLES1 PTTG1IP SLC25A16 RWDD3 DNAJC18 C1ORF63 TMEM71 ZNF253 NEBL ENTPD3 REPS2 HIST1H2BC HOPX RPL38 PNRC1 TRIM2 GALNT3 TCP11L2 HIST1H2BK SLC2A1 CYBRD1 FNBP1L TPST1 AIF1 C2CD2L VPS37C DHRS7 H6PD GRINA ALOX5 GIGYF1 DNAJB2 HCAR2 LMNB1 SHCBP1 DDIT4 ALCAM OPN3 HADHB ADORA3 TEX2 MAP3K6 MIB2 CPA3 AKT3 SLC25A29 PTGS2 COL18A1 NTRK1 PHOSPHO1 RMND5A VPS9D1 TGFBR1 ASB7 PLAUR USP32 ARHGEF5 ZNF217 WIF1 SP6 RAP1A SORL1 OR2A5 TMEM164 ST6GALNAC2 SDK2 KDM4B CUX1 RGL2 ZNF646 ULK1 ATP8B4 HIST1H2AE IGF2BP3 ALAS2 PAQR9 CLEC4E CD177 JPH3 NAMPT LRRC4 BASP1 KLHDC8A ARNTL CD59 FTH1 PCBP2 TNS1 YBX1 PPP1CB ADIPOR1 EEF2 TSPAN7 SH3BGRL RPS19 AMMECR1L EEF1B2 RPL10 SERPINE2 LAMP2 EIF3K RPL22 MYH10 CCNI CETN2 TP53INP1 RGCC FUCA1 TALDO1 TRMT112 RAB11A SELENBP1 NCF4 IVNS1ABP VCL AGO4 C10ORF128 ARRDC4 PIK3R6 C17ORF99 BPI PADI4 KIAA1551 UCMA ERMAP PGLYRP1 LONRF3 LRRK2 HDAC9 NTNG2 FAM129C TG TMEM120B SEC31B CYP4F3 PDLIM1 MMP10 BABAM1 YPEL5 CDC7 MGLL CMC1 PPP3CA HEBP2 RPL32 MXI1 ADORA2B PARD6A ACRC SRXN1 FAM46B FAM129A C15ORF48 CD46 NECAP1 HIST1H1T GCA CCDC153 GCHFR DGAT2 SLC13A4 CNOT8 C9ORF84 HIST1H4E PELI2 CEACAM8 RP2 TEX14 PIGL TESK2 CRISPLD2 HIST1H2BG CD1B ORM1 CCDC28A TMEM56 BBS2 AMFR IFT74 LRIF1 BCL10 RPL22L1 ZNF573 FOXD1 KCTD12 C1ORF174 CETP LPCAT1 FAM110C P2RY1 FBXW11 CPEB2 SLC28A3 RRAGD FAM210B CERK PYGL SERF2 SRGN CSF2RB ACTR2 HEXIM2 SESN1 HSPA1L SOBP GNE PPTC7 NRL DENND3 CHST2 BCAR3 XYLT1 ENTPD1 NEK6 ITLN1 IL1RL1 ADAM19 FCER1A ETV3 AKAP7 BDKRB2 OLA1 TIPRL PET100 ZDHHC11 GK AQP9 KIT GNAQ EGLN1 PELI1 APMAP UCK1 WIPI1 SPP1 TMEM183A GALNT1 COX6B2 ABHD12 CDK5RAP3 CHMP3 ABHD5 POU3F1 RPGR PARM1 NIPA2 ATP7A SUV39H2 ZNF8 CCNYL1 TMCC1 DMPK KCTD7 CLTB EEPD1 BCL6 OLIG1 PROK2 ANKRD22 RGS18 CYSTM1 NFKBID RTN3 RAF1 VPS37B RPS6KA2 WBP1L AP1S3 HEXIM1 RAB6A IL6R DGKG IGF2R NFAM1 ZBED5 ZBED4 BMX MEGF9 NDUFAF6 USP28 LPP MPHOSPH6 ZBTB18 CDK19 WNK2 CAMKK2 GCNT1 CCNG2 TRA2A IFT57 MAP3K5 GSR SLC19A1 RAB32 FIG4 IDO2 PAK1 RC3H1 ZNF749 ZNF26 CD300LB CTBS LPCAT2 FAM167B SAMD8 CYP2U1 TGIF1 SLC2A14 EYA3 RASSF2 POLD3 RPS4X USE1 TCL1A PRDX6 DSE TMOD1 CYB5R4 PFKFB4 EIF3L ARID3B RUSC2 MOK FAM173B CSGALNACT1 NFIX CPD DCUN1D1 SULF2 FAM43A ZNF608 ICA1 KIAA0319 QPCT IFRD1 BTF3L4 NR2F6 SENP2 WDR20 CAMSAP2 CLIP1 CHML HTRA2 CNST GPR135 HECW2 DENND4A SIPA1L2 ATP11A PDCD5 SLC41A2 PRLR HAL RNF10 HIST1H3E SMNDC1 LYSMD3 CDK5R1 PTPRN2 HIC2 MSL1 KLHL2 CCNJL RELL1 THAP5 PHAX UBALD1 COL15A1 PPM1F CLYBL RFX2 SENP5 SETD9 ARHGAP39 SSFA2 FOXN3 ZNF124 RAB11FIP4 FAM220A SPECC1 ANKRD2 SH3BP5L STRADB PXT1 SLC35E1 IPMK PPP1R12B RPRD1A C7ORF73 FCHO2 MOB1B PGM2L1 SLC25A6 KATNBL1 EXOC6 ELFN2 FAM135A EFCAB2 CDKL2 ABLIM2 KDM1B MMRN1 PLXNC1 CDKL5 MAP3K15 CD300LD SLC12A5 S100A1 OSBPL9 POLR2D MUC12 ZNF853 MTMR10 SLC25A19 CCDC125 PCDHGB7 PLEKHM3 FOXD2 ZFP62 BNIPL HOMER3 CNR2 ZNF814 RUNDC3A SHISA8 NGRN AK7 C7ORF41 PION KAZN ZCCHC8 UBE2G2 EFR3B ASPRV1 HIST2H2AA4 SLC24A1 TMEM66 NFASC MST4 PTPLA ANGPTL1 GKAP1 TEKT1 EFHC2 IQCG FAM92A1 EMR3 B3GALTL PDE6H FUZ HDGFRP3 RSPH3 TRIM58 HYAL3 EPB49 RBM23 ICAM4 C10ORF12 GAREML FLJ44635 FCRLB FAM159A CHRNG ZNF429 METTL21B C9ORF106 KIAA0141 DLGAP1 NHSL2 RTN1 KIAA0146 FAM69A ADGRF3 C1ORF186 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CEP250 UHRF1 EPB41L2 ICOS AKAP8 RRP9 CTLA4 DDX1 CENPF ACSL3 POLA1 PHB2 OAS1 DNMT1 TUBA1C CLIP4 RARS FYN MOV10 CD8A ACADS PHF7 ASCC1 MRPL9 SPTLC1 FAHD1 CDK5RAP1 ZFAND1 CHEK2 NT5DC2 IFI27 FAM216B APOBEC3A UTRN AGAP1 HIST1H1D STMN1 DDB1 ACLY PLK1 EXO1 DHCR24 MYBL2 TOP2A ZWINT CDCA8 CCNA2 CLSPN TK1 EZH2 CCNB2 GTSE1 CDKN3 UBE2C AURKB E2F2 NEK2 KIF18B KCTD3 NUF2 DEPDC1B CDCA5 HMMR SEC23B SPAG5 BUB1B MCM2 KIF2C KIF14 FUCA2 ASPM AURKA DLGAP5 ESPL1 BUB1 RRM2 CDK1 CDC6 E2F1 BIRC5 ORC1 POLQ KIFC1 MCM10 KIF15 CDCA2 KIF11 BRCA2 TPX2 STIL CCNB1 ANLN EPS8 CEP55 CDCA3 CDC20 KIF23 SKA1 HJURP TRIP13 CENPW TTK HP MKI67 KIF20A DTL KCNMA1 SLC43A3 NCAPG TYMS RHEBL1 SH2D2A G0S2 IL18RAP DSCC1 ELANE CTSG HMGA1 CCNE1 LTF MTOR SH2D3A EVPL ARHGEF16 WDR7 LRP5 PORCN HDAC3 IPO7 PRC1 TPP2 ELP4 IQCE MNT SMC2 CXCR3 CDC25C E2F8 UBE2T HIST1H2AJ CENPA KIAA1524 FBXO5 MTFR2 ESCO2 SPDL1 CHEK1 RAD51 SLAMF7 GINS2 GIMAP7 C17ORF53 SH2D1A CKAP2L CD28 PARPBP FAM83D SKA3 NCAPD2 SPC24 SGOL2 LCK CRTAM OIP5 GZMA ERCC6L NUSAP1 CKAP2 CD3D MCM5 THEMIS CX3CR1 PBK RACGAP1 AUNIP SPC25 ZWILCH ARHGEF39 CENPM SGOL1 DEPDC1 MAD2L1 SLAMF1 NCAPG2 CCR5 HMGB2 CD2 NDC80 POLE KIAA0101 RAD51AP1 PTPN7 MB PSAT1 CDT1 LRP8 POLE2 GINS1 CHAF1A IL2RA CCNE2 DHFR CCDC18 PPA1 AIDA ICAM1 HIST1H2BI GBP3 FABP5 UQCRC2 EIF3I PSMC2 SERPINB9 GIMAP8 ARRDC3 DHX15 ZBTB16 BMS1 NUCKS1 RAB3GAP1 PGRMC1 DEFA3 FBXO40 VAMP1 OLFM4 C6ORF52 E2F6 HTR2B FUS TMEM213 ZNF367 HMGB3 CMSS1 GTF2E1 RRM1 MND1 POLD2 RNASEH2A SLC29A1 PTTG1 AHCY STK39 SUCLA2 SLC25A15 BOLA3 ACTL6A ANP32E ZW10 NUP37 HTATSF1 PSMD14 NOL11 PUS7 PNPT1 GMNN NUP107 EPRS SNRPA NUP93 HIST1H2BE TAF4B E2F7 SRSF2 HIST1H4C HIST1H1A DIAPH3 ATAD2 MAGOHB CDCA7 MCM6 GSTCD FEN1 STRA6 SLFN5 MOCOS ROR2 WDR90 PRG2 NEU3 FAM185A SFXN3 GPRASP1 MCM4 TTF2 HHAT SMC3 SNRPA1 SLC26A2 RFC5 LRRC45 NEB NCAPD3 USP44 KIF3B CCDC42B CORO2A ATAD5 SDAD1 OSR2 KLHDC7B DUSP4 SLC2A10 NUDCD1 OPTN HMGN2 MPO XPO1 GZMB SRSF5 CDON SIRT4 CEP152 CACNB2 PDK1 SDC3 CGA CORIN CD40LG ITGA6 TIMM23 VTA1 PEX3 HIST1H1B XPNPEP1 PLRG1 TMEM165 SCO1 TMEM209 EFTUD1 FAM114A2 MTA2 KTN1 PTP4A1 PON2 COMTD1 AACS MATN2 SMPD1 DDX39A CTPS1 RBM6 PLXNA2 FDPS POLR3A AAGAB FDFT1 EWSR1 SSRP1 PTPN11 ACACA CDC27 SMC4 DTYMK BHLHA15 MAPK7 GPC1 BNIP1 RAB9B SLC38A9 FOXP3 DEFB1 ZNF182 USP45 GALK2 ENOSF1 RFC1 SLC25A45 ABCA5 LRPPRC TAF2 CYP51A1 ABCB8 SLCO4C1 RFX3 FUBP1 NAA15 RCN1 MCM3 TIAM1 TFDP1 LIN9 ORC5 THOC3 TRMT6 C16ORF59 POC1A TOPBP1 TRNAU1AP BRCC3 FITM2 DIP2C SH3RF2 EIF2B1 ANAPC15 MRPL3 MYL6B PIF1 DPY19L4 LANCL1 VWA8 GPSM2 DENND4C RAB39B IGFBPL1 RFC3 DMXL2 CCDC82 WDR18 NLE1 GALE PFKP SNRPF MYCBP SLC41A1 HNRNPA3 EXOSC9 ZNF441 HOOK2 TMEM117 GABBR1 TTC28 VWA5A PCTP ECI2 HIST1H3C DOCK10 HIST1H3I HIST1H2AH IDUA KCNK1 CNTLN PLK4 CEP128 ZNHIT6 RABGGTB MCM8 SORBS1 DSN1 DENND2D SCAPER PROSER1 PDS5B EXOG ST7 GFM1 IDH3A EIF2B2 PUS1 IMMT ZDHHC16 RIN1 CCDC25 INA COQ7 ZC4H2 FAR1 PIDD IQCD TMEM48 C4ORF21 MR1 WHSC1 PREPL WDYHV1 C16ORF88 DNAJC13 CCDC176 KIAA0368 CEP41 GALT KIAA1841 FAM189B ARV1 KIAA1429 POLR3B SYNRG FSD1L PBX4 ANKRD24 PHYHD1 IL12RB2 EXD2 SEC61A2 C6ORF70 C9ORF174 PRG3 FGFBP2 IDI2 ZNF311 C14ORF79 DIAPH2 L2HGDH KCNRG ANKRD32 MLF1IP HNRPLL KIAA1737 HIATL1 SIRPG RAB3GAP2 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CANT1 PPBP IL1B FCGRT MAPK3 GDF15 CD14 MAP1LC3A STX3 HIST1H1C TMUB1 IFITM3 MAST4 ARRB2 ANXA3 PF4 LYN FURIN TUBA8 HSPB1 FAR2 TLE3 RYBP TMEM54 UBA52 KIAA2013 CRK SDF2 TLE1 SRPK2 HERPUD1 SLC23A1 MARK2 AKAP8L ICAM3 PTK2 RAB5C GRB2 OXSM TMED4 TM7SF3 BRI3 CABLES1 TMEM30A PTTG1IP FKBPL ADK CHMP2B C1ORF63 DEDD2 PLEKHO1 VKORC1 KRT18 HIST1H2BC HOPX PNRC1 PAWR TCP11L2 CYBRD1 FNBP1L HIST1H4H HIST1H2AC PLA2G7 TPST1 AIF1 STARD10 FTL MAN2B1 TMEM127 DHRS7 VASP GSN H6PD AKT1 PLCB2 GNB2 MAP3K11 SLC15A3 GALNS GAS2L3 LMNB1 SHCBP1 DDIT4 ALCAM OPN3 CTSZ TEX2 MMP23B MIB2 NCR3 AKT3 TPPP SLC25A29 COL18A1 MSC CCL4 ZNF540 CGREF1 CDS2 TUFT1 GADD45G BAD ZFP36L2 CRB3 MMP25 IRF8 BCL3 FOSL2 CEBPB KDM4B TBL1X RGL2 ARHGAP27 TMEM8A CYSLTR2 CREG2 GATM GLIPR1 FCGR2B DNASE1L3 IGF2BP3 CFD IL1R2 PTAFR NFKBIE BASP1 KLHDC8A NINJ2 CD59 FTH1 FOS MAP1LC3B PLTP DUSP1 TXNIP NFKBIA RAMP2 EGFL7 JUNB TSPAN7 SMAGP DAZAP2 DRAM1 BTG1 SERPINE2 LAMP2 TAGLN GABARAP PRDX5 C19ORF43 ISCU LAPTM4A GLUL JUND RHOQ TSC22D3 SDPR ESAM FUCA1 JTB TYROBP TALDO1 HSPH1 TRMT112 TEX261 ATP6V0B CDIPT JDP2 RAB11A DNAJB1 MKNK2 ALOX5AP HCK NCF4 IVNS1ABP TPRG1L SAT1 TNNI2 GTF2B AGO4 S100A13 C10ORF128 ARRDC4 ZC3H12A LST1 KIAA1551 WSCD1 UCMA TLR9 NTNG2 BBC3 AMOTL2 DUSP5 KIAA0907 SERTAD1 ZBTB34 ALAS1 PDLIM1 MMP10 TMEM205 RBPMS2 TAF12 WDR83OS MGLL CXXC5 PPP3CA TSEN34 ARG2 ADORA2B PARD6A SRI TTLL13 FAM46B FAM129A C15ORF48 CD46 NECAP1 MAP3K14 PPP3R1 EBI3 LAT2 ETV6 BID RASD1 C4ORF45 TSPAN33 DGAT2 IL27RA CNOT8 GP9 CCNB1IP1 CASS4 PELI2 PER1 SIGLEC10 CCDC28A KBTBD7 MAD1L1 METRNL SLC35E3 C3ORF80 LRIF1 BCL10 FOXD1 KCTD12 C1ORF174 GLIS3 RALB CETP YTHDF3 FAM110C ZNF581 C20ORF24 SERF2 PACSIN2 MSRB1 PF4V1 GPSM3 EIF1 SNN RNASET2 SERP1 HEXIM2 SESN1 ZNF221 SOBP BANP CHST2 IL1RAP BCAR3 ENTPD1 NEK6 ITLN1 BACH1 UPB1 FADS2 IL1RL1 UNC80 ADAM19 TUBB3 FAM101B ACTG2 RDH12 CCSER1 IFNGR1 RNF135 IRAK1 TRAPPC5 LYL1 SIGLEC5 RIN3 DOK3 HLX DOT1L EGLN1 TFEB SYK PELI1 RAB4B TBC1D20 HMOX2 NR1H2 UBALD2 UCK1 TRIM11 SPP1 GALNT1 COX6B2 ARPC1A ARF4 C4ORF3 ABHD12 ALKBH5 ABHD5 PLEKHJ1 MID1IP1 GAB2 NIPA2 HOXC4 ZNF8 MEF2D KCTD7 CLTB HOXB6 PLK3 HDAC5 SIRT7 FAM174B TLE4 EIF1B CYSTM1 NFKBID TMEM154 PQLC1 CCM2 CHFR VPS37B DOCK6 WBP1L FCRL3 TUBB4A SLC31A2 RAB6A NPL SLC5A3 NFAM1 CLPTM1L CELA2A NDUFAF6 CAMKK2 PDGFB IFT57 ARHGAP6 SLC19A1 RAB32 BIK PCDH17 CRTC2 RNF130 PAK1 PPM1D EMC6 CTBS NRBF2 FAM167B SAMD8 TMEM179B TGIF1 PPP1R9B EYA3 RASSF2 TTC9C GTF3C5 HRK USE1 PRDX6 TMEM59 RNASEK TPD52L2 PLCG2 TXNL4B ARID3B ZFX TMEM55B ZSWIM4 SKIL FAM173B CSGALNACT1 FAM49A FAM43A APBB2 CHST11 IFRD1 NR2F6 ADAT3 NCK2 SNX18 OPHN1 A4GALT FAM98C UBL7 C16ORF72 CNST GPR135 CPEB3 TGIF2 KLHL36 ARL10 PPM1L APPL2 TCTN1 ACOX2 EHD3 SH3BP5 CHIC2 PDLIM7 THAP3 HIC2 MSL1 KLHL2 KIAA0513 MMP28 SH2B2 SNAP23 PWWP2A SETD9 ARHGAP39 YPEL2 SSFA2 FOXN3 RAB11FIP4 P2RX1 ANKRD2 ZNF394 SLC35E1 GNG7 PPP1R12B C7ORF73 REEP3 ZNF775 ZNF358 MLL4 DGCR14 KATNBL1 ELFN2 CEP164 PHTF1 TESK1 KLHL25 ABLIM2 CDKL5 SHC2 C17ORF59 TMEM175 NEIL1 CD300LD S100A1 POLR2D SS18L2 ZNF853 RNF169 FAM131A SLC25A19 CCDC125 FKRP TMEM81 BNIPL HOMER3 ZNF843 CNR2 SHISA8 EGFL8 RSPH9 NMNAT3 ZNF354B KAZN KCNG2 EFR3B OSBPL2 TMEM41A HIST2H2AA4 NFASC PTPLA TBC1D14 NFYC VRK3 C20ORF111 KCTD21 PHF15 ICAM4 DSCR3 CATSPERG GAREML FCRLB TAS1R3 FAM69A KDM4E LOH12CR1 KCNK12 ZNF688 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBB TIMM10B SUMO1 CCL5 GHITM CISD3 ETFA PTCRA DPEP1 EPB41 GOLGA7 RBX1 ZCRB1 GABARAPL2 ERG CRISP3 CALM3 UBA52 PSMD4 OAS1 TST RAD23A NDUFB9 DHRS11 PRKAR2B STOM CAT GUCY2C FBXO9 SLC25A39 MDH1 RHBDD3 BRI3 KLF1 C1ORF50 TMEM80 FAHD1 RILP PAIP1 CD55 RWDD3 NDUFB6 IFT122 ENY2 FECH ZFAND1 BCL2L2 PPP1R14C UQCR10 ENTPD3 ERBB3 HOPX C9ORF116 RAB25 NDUFB2 RHOBTB3 COX6A1 SCIN GADD45A CKS2 LCN2 AIF1 NFIA RPS14 RPL7 FTL ALOX5 DDB1 FBXO6 CD101 CLTCL1 DHCR24 C14ORF119 C5 CREG1 SLC16A1 GLRX E2F2 POMP NUF2 NDUFS7 MCM2 ASPM CDK1 BLVRA GALK1 GSTO1 VPS25 CBR1 IFI27L2 TRIP13 HP MKI67 PRELID1 RNASE3 PSMB7 PDGFD S1PR5 CCL4 CAMP HINT1 RMND5A CNOT6 B4GALT4 ELANE CTSG PLAUR PLCD1 LTF AIM1L RAP1A SOX6 MRPS36 MS4A6E FCN1 NPEPL1 CDC25C CENPA ESCO2 GINS2 PYCARD SH2D1A FAM83D SPC24 GZMA CX3CR1 CENPP LRR1 CD2 GZMK KIAA0101 RETN S100A9 MYL4 ALAS2 PAQR9 SNCA PLAC8 CD177 TNFRSF12A GLIPR2 NINJ2 CAV2 RNF7 SELK PPP1CB ADIPOR1 MYL12A TXN ATP5J ANAPC13 H2AFZ COX7A2 EIF3I PSMB6 COX8A NDUFS3 ARL6IP4 RAP1B SH3BGRL3 PAIP2 CCNI ATP5H SHFM1 ARRDC3 PTGR1 RGCC JTB NDUFA2 BMS1 TALDO1 ROMO1 S100A16 MPC2 MXD4 MYEOV2 SELENBP1 C1ORF198 NDUFA4 GUK1 GLRX5 RAB5A ATP5C1 GPX4 COX14 DAD1 BNIP3L DEFA3 BPI ERMAP S100A12 PGLYRP1 C6ORF52 IL23A TG CITED4 TP53INP2 YOD1 FOXO3 ZNF263 OST4 ATRAID MRPL34 ISCA2 MRPL46 MRPL24 BABAM1 CDC123 ATP6V1E1 GYS1 TMEM208 NDUFAB1 HMGB1 SLC25A11 LAMTOR5 ZNHIT1 GPR160 DYNLT1 TTC1 MAGOH AMZ2 ICT1 PLGRKT CDC26 SAR1A BOLA3 NOSIP NDUFA8 WDR83OS POLR2J FAM96A ATP5L PCMT1 UQCRH AP3S1 EPRS C15ORF61 TMEM50A SNX10 CCDC53 DECR1 ZFAND2A SOAT1 NCOA4 MKRN1 HIST1H4C COMP CREB3L4 SRXN1 SRI TPST2 IK NARF SMIM1 MAGOHB MCM6 GMDS VAMP5 S100A8 ROR2 MARCH5 TSPAN32 NFE2 TESC IGLL1 CEACAM8 TSTD2 ORM1 SNRNP25 SNRPA1 APOBEC3B GMPR NT5DC1 NOSTRIN BPGM RSU1 SERF2 SEC61B MYL6 FBXO7 CLIC1 TAF10 COX5B BLVRB TCEB2 EIF1 MYL9 PRTN3 ILK CD52 GZMB CALM2 SLC25A42 CENPV ITLN1 SLC16A10 SH2D6 GFI1B PRDX2 GATA1 COPS4 POP4 TIMM23 PSMD7 PSMD9 SNF8 VPS29 EXOSC1 ANAPC10 TXNL4A ACP1 RNF5 UBE2H RIOK3 CLPX CLPP TAX1BP1 MRPS12 TMEM11 RABIF UGP2 XPNPEP1 APMAP IFITM10 HTATIP2 NECAP2 GDE1 GID8 STX18 WIPI1 ZNF330 PPM1A TPM1 CMAS C9ORF78 C4ORF3 C6ORF62 BLOC1S1 C11ORF71 CTNNBL1 TTC23 HSPB11 MRPL33 MZT2B GNPTG MPC1 TBC1D7 ANKRD22 ZFAND2B LRRC32 CTTN SIVA1 KAT2B AGFG1 NPL FXN BMX CDC34 CDKN2A FSIP1 AK9 MSRB3 COPS8 CISD2 HIST1H2BJ DEFB1 RAB24 ZNF627 GALK2 ALDH1L1 CTH SLCO4C1 NIPAL1 TMEM138 TOP1MT FBXW2 H3F3B RHOC MGST3 TMEM70 MRPL23 JOSD2 CTDSPL DBNDD2 MAGED2 TBC1D22B C7ORF50 DPCD SYNGR1 CARHSP1 NDUFB8 NFIX MCTP1 AGTPBP1 QPCT LIMS1 PHLPP2 PHACTR2 C12ORF49 HIPK1 MAP4K5 OXLD1 MRPL55 ZMAT5 CCDC167 ECH1 RFXANK ATPIF1 C14ORF2 TMEM9 ATPAF2 ARL4A CNIH4 MGST2 GCDH HDAC11 EIF3M EIF5 MRPS18A PHPT1 FBXL15 PLCL2 UBXN2B CCNDBP1 DCAF12 PITHD1 ADAMTS7 PLA2G16 SFXN4 FAM118B TSPAN2 UFD1L ZMYM6NB MINOS1 ASCC2 RAB3IP ZNF622 FAM213B ALKBH2 DPM2 GPR146 PRKCDBP CCDC51 EIF2B2 SPECC1 SMAP1 MRPS28 PSME4 ISCA1 FAM46C ARIH2 EMC8 C7ORF73 IQSEC2 TM2D1 MESDC2 SLC18B1 TSSK3 FAM204A DRG1 MRPL53 XRCC6BP1 MED28 PGA4 DCAF8 PNMT FAM200B XK C2ORF15 COA1 MEST DLG5 SNAPC5 PHYHD1 ZSCAN5A CDADC1 ZSWIM7 DUS2L KLRC3 C6ORF1 TRIM58 HYAL3 PRG3 ICAM4 FAM104A C22ORF32 C10ORF116 FGFBP2 IDI2 SLFN12 FAM58A C9ORF89 PTPLAD2 C11ORF83 C2ORF47 FAM206A C16ORF91 PSMG4 CCBL2 PCGF1 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CANT1 PIK3R2 FRMD7 MDN1 CTDSP1 MACF1 HEATR3 MAST4 FURIN RNF41 CLCN6 TLE3 SMAD3 BRD2 UHRF2 NFATC2IP UBAP2L CRTC3 TGFB1 NUP85 YWHAH MTCH1 HSPA8 MARK2 APP LNPEP PAICS PLEC RAB5C GPHN ATXN2 NOTUM SBK1 CABLES1 LRRC56 OSGEPL1 NR4A2 PTPN13 GATAD2B HIST1H1E STARD10 ZBTB20 NACC1 TAOK2 C1QC IL4R MAPK8IP3 DAZAP1 TOR1B TMEM127 INPPL1 VASP LDB1 SF3B4 GIGYF1 GNB2 PPP6R1 PIP5K1C APH1A RARA TRIM65 ARHGDIA SNRNP70 SCAMP2 TMEM106A ADORA3 ACVR1B RAPH1 NOG TPPP SLC25A29 PDZD4 KLF2 B4GALT1 KLF16 MAVS SERHL2 TRAK1 BMP4 ZNF707 HMGA1 RDH13 ZBTB42 BCL9L LSR SEMA4B PPP1R37 SLC4A2 PYGO2 DVL2 WNT10A DACT1 PNN IRF4 CASP2 TCF3 DYRK1B SCAMP4 PACS1 ZNF865 RAB11FIP3 KDM4B NUAK2 PITPNM1 LFNG PLEKHG3 ARHGAP27 EPN1 ERF AGAP2 MMS22L GPR15 TXLNB JPH3 SLC25A22 SOCS1 TLR3 ZNF711 HPCAL4 BTG2 BMPR2 CNN2 GRASP CLIC5 U2AF2 SH2B1 AMMECR1L TAGLN NSMF HIPK3 TSC22D3 CAMTA2 FAM53B RBBP4 MKNK2 ELOVL1 FASN MARCKSL1 POU2F2 MFHAS1 PIK3R6 SLC25A25 WSCD1 KBTBD8 ZNF484 HDAC9 LOXHD1 NTNG2 CYTH4 FAM129C RTN4R SEC31B IRF2BPL MSL2 ATP6V1C1 AP1S1 TOMM34 CKLF CYP20A1 PTDSS1 CXXC5 CHTF8 SUCLG2 ARHGEF18 TOB2 TAF4B GRB7 PARD6A LENG8 MN1 MARK4 TP53TG5 MTFR1L FANCG SIK1 RASA1 ELOVL4 GRAMD4 CIITA ASB13 TRIM6-TRIM34 TNFRSF13C CXCR5 GRIN2C NCKAP1L SNX20 DGAT2 IL27RA SPIB FAIM3 MAP1S XRCC1 HIST1H4E PRPF39 MAN2A1 ALG10B ALYREF SMG1 IFT74 CCDC106 FOXD1 ENTPD4 PPP1R10 BTK SRRM2 FBXW11 ZBTB33 TRIM26 AMPD2 RASGRP1 PDE7A ZNF221 SOBP XKRX ZNF610 GNE PRR22 RALGDS IL1RAP BACH2 NR4A1 APBA1 IL1RL1 ADAM19 GRIK5 C1QTNF1 TGFB3 ANKRD34A CD40LG RAB35 SENP3 RIN3 LIPE DOT1L TFEB NFKB2 TGFBRAP1 TP53RK TRIM11 ZNF34 AIG1 ARL8A CLPTM1 SMARCB1 NDE1 ZNF324 NIPA2 ATP8B1 ITFG2 SLC10A7 TMCC1 MEF2D CYB5RL ACAP3 APC2 RABEP2 SYNE2 TAF1C NCOR2 CRTC1 RHOBTB2 JAK3 NFKBID RAPGEF1 BRD9 RHBDF1 FBXO31 DST SLC9A1 NISCH LRRC47 RPS6KA4 TAB1 PLN SLC7A6 PPARA DGKG SLC5A3 PRKCE SREBF2 ZNF674 SRF ECE1 GANC SUFU PLXNA3 KCNH3 ZBTB4 KDM4C SIPA1L3 MAST2 ABCC10 EHMT2 MTAP FAM227B TNPO2 LRBA CYP2D6 ATP2A3 STX17 CRTC2 ADIPOR2 CD79A PLD1 FANCC ZNF175 ZNF284 ZSCAN12 TREML2 MTA1 RBM4 SLC5A6 TGIF1 PPP1R9B TERF2 PATZ1 REPS1 TTC9C ING1 TNFRSF6B MAP3K9 TCL1A DSE PCDHGA9 FBXO2 EIF3L USP42 OSBP EIF4ENIF1 ATXN2L ZNF764 KCTD5 MTMR9 MED26 ZNF335 RUSC2 ZFX KDM2A TMEM55B KIAA0753 ELMSAN1 C18ORF25 ZSWIM4 FAM173B RHOF MYSM1 ZNF395 ARHGEF6 FAM43A ZNF697 CNP CAMSAP2 KAT6A SACS TAF5L RPRD2 ZMIZ2 C2CD3 ZNF84 GPR135 SNAPC3 CPEB3 TGIF2 DENND4A FBXL20 RFX1 MPRIP FAM168A GRAP GDI1 PRRC2A TCF20 GPBP1L1 HIST1H2AK CLASRP HIC2 ZNF721 CIZ1 DUSP14 MESDC1 ZC3H3 AES TBCK PALD1 FAM222B CNNM2 ZDHHC8 SEPT6 ARHGAP39 ZNF717 INVS ZNF124 GNL3L ZNF213 SPPL2B PEX14 POLM DTX1 SH3BP5L UNK SLC35E1 ZNF418 PPP1R12B C16ORF52 INO80E SH3GL1 ZNF358 KLC2 SOGA1 POMGNT1 GPC2 KIAA1967 HAUS3 EML3 ADNP FAM120C SOLH MLL2 SAMD4B TESK1 ABLIM2 KCNA3 ZNF512B EPM2A PRMT7 CMTM1 COG2 SAP25 UBE3D TRMT61A UBE3B TRRAP MRPL49 TTC24 PEX12 PTCD1 ERCC3 BBS1 ZNF823 DPH1 ZNF619 FBXO46 C16ORF70 IQSEC1 ZNF700 BNIPL HOMER3 CNR2 SHISA8 ANKRD23 PCDHGA10 SFI1 GATAD1 ZNF69 PHF17 RCCD1 KAZN AFF3 WNK3 CBFA2T3 TULP3 TMEM25 MORN4 EFR3B CAMK1D CRIP3 PRR3 CSTF2T ZNF577 GOLGA6L9 EVC2 ERI1 KIAA0355 PCDHGA8 C13ORF35 ANGPTL1 KDM2B GKAP1 TBC1D14 ATRIP C12ORF40 MAMU-DOB RBM23 NOP9 PHF15 RLTPR TEAD2 OLIG2 CXORF57 TAS1R3 METTL21B DLGAP1 XRRA1 TRIM68 C9ORF37 KIAA0226 TH1L SEMA5B NEK4 ZFP3 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBB BCL2L1 SARS2 CCL5 WFIKKN1 TRMT1 UBXN6 ICOS DAAM1 SLC26A6 EPB41 MYO1D GOLGA7 GABARAPL2 SLC46A3 PIGO GPX1 PHB2 RAD23A EPB41L5 CLIP4 NARS2 BAG6 ALG8 RARS ZNF575 STOM MOB2 CD244 GGH FBXO9 LYRM5 SLC25A39 AGBL3 FAH ZBTB44 TMEM80 SIAE RWDD3 FECH ZFAND1 MCF2L PPP1R14C ENTPD3 RPS12 ZNF827 GADD45A ACOT13 LCN2 GCNT4 FTL PNPLA2 TRPV2 ALOX5 FKBP8 BSDC1 HK1 DDB1 CLTCL1 TOP2A CCNB2 SLC16A1 E2F2 KCTD3 MCM2 KIF14 DLGAP5 FADS1 GPNMB ORC1 TMEM45A ANLN CEP55 SKA1 HP NKIRAS2 YPEL4 ESRP2 SEMA4C TPM2 RHEBL1 CST7 S1PR5 CCL4 PRSS57 RMND5A CNOT6 DSCC1 PKD1 AXL ELANE B3GNT9 CTSG LTF PPP1R16A GIPC1 SLC7A5 ITPR3 ARHGEF16 TNK1 WDR7 ANKRD6 PORCN RAP1A MAPK11 RGS3 IQCE KLRD1 CDC25C GRAP2 ESCO2 RAD51 GINS2 GIMAP7 C17ORF53 SH2D1A GFI1 SPC24 CRTAM GZMA NUSAP1 CKAP2 CD3D CX3CR1 CD2 KCNN4 GPR171 CHAF1A ALAS2 PAQR9 HBB SNCA CD177 CCDC18 PIM1 MITD1 UBA7 TMCC2 TNS1 BAG1 PPP1CB UNC45B RNF187 KLHL5 NDUFA3 RAPGEF2 PXDC1 GBP3 AGER COX8A CCNI HCFC1R1 PTGR1 NDFIP1 RGCC CA4 S100A16 AQP1 MXD4 PIGQ IGFBP7 WNK1 SELENBP1 C1ORF198 NUCKS1 GLRX5 RAB5A PGRMC1 GPX4 BNIP3L ZNF880 DEFA3 DUSP8 CCM2L BPI FBXO40 OLFM4 TREX2 C6ORF52 IL23A ZNF596 ANO8 SLC14A1 QPCTL FAM161B MECR CMSS1 BABAM1 MND1 PTTG1 SF3A2 PLGRKT BOLA3 SPIN1 WDR83OS SKP1 EPRS AMIGO2 MXI1 TMEM245 FAM117A NCOA4 HIST1H4C COMP DIAPH3 MCM6 NIPSNAP3A EFNA3 ZBTB22 GMDS STK32C PCED1B TRIM21 ROR2 PRG2 TNFAIP8L1 RGS10 INPP1 FAM185A TESC IGLL1 VNN1 C3ORF33 TSTD2 GYPC ORM1 ABAT WDHD1 LRRC45 EOGT NCAPD3 ACN9 KIFC2 C19ORF66 ORC4 WSB2 UCP2 PJA1 MB21D2 CAPN12 OSR2 KLHDC7B DUSP4 FAM210B MDK BPGM MMD FBXO7 TCEB2 XPO1 GZMB SRSF5 GPR56 ARHGEF3 SLC25A42 PDK1 CENPV FHL2 ITLN1 STK17A DPEP2 ADAM12 PLSCR1 FXYD7 PRDX2 GATA1 POP4 PSMD7 UBE2H RIOK3 CLPX BSG TAX1BP1 B4GALNT4 TFR2 TARSL2 NECAP2 PSMC5 PLRG1 PPM1A TPM1 CMAS C9ORF78 BST1 CIRBP TBC1D17 CCS TTC23 RAB3IL1 TRMT2B DHX29 HECTD3 NUDT17 PODXL LSS ASB1 F8A1 ST20 TARP PPDPF ZFAND2B SLC38A5 RSAD1 MAF1 RNF123 ZG16 FXN GDF9 CDC34 EFEMP2 PIWIL1 LIN7C CYTH2 BACE2 MSRB3 PRR5 RAB9B MRPS7 ZBTB25 ZNF17 ALDH1L1 IL17RC PSMF1 FFAR3 SLC22A5 GCSH NIPAL1 CDK8 RCN1 MRS2 RBM38 POC1A IFRD2 WDR4 TOP1MT FBXW2 CCDC134 SLC25A20 JOSD2 VANGL1 MAGED2 DIP2C FOXJ2 SNX19 SH3RF2 CSPG5 C7ORF50 OSBPL7 PIF1 CARHSP1 STOML1 NFIX DSC3 MAN1A2 PUS10 VWA8 GPSM2 ZNF277 RAB39B C1QTNF6 LIMS1 PHLPP2 HIPK1 MAP4K5 TMEM187 NLE1 CIB2 CLPB PIP4K2A UBE2O FRS3 FAM53A PHKA1 TTC28 TTC39C SUOX ACAD11 HDAC11 HIST1H3C RNF10 VPS33A FBXL15 ST6GALNAC4 PLCL2 DCAF12 PITHD1 KCNK1 UBALD1 DMWD NECAB3 VWA5B2 ADAMTS7 RNF126 ELOF1 SSBP3 IL17RE PLA2G16 WDR60 TSPAN2 ZMYM6NB MARCH3 C11ORF49 NBAS SORBS1 ASCC2 FAM213B PDS5B ALKBH2 GPR146 HSD11B1L PUS1 SMAP1 PSME4 ISCA1 FAM46C ARIH2 NAT6 CHCHD7 UBE4B RNF217 STRADB ZC4H2 C7ORF73 IQCD KIAA1984 MEIS3 WDYHV1 BSN AKAP6 RAB42 TSSK3 CNTNAP1 DOK6 ODF2L PEX11G OGFOD2 GALT TMEM8B PRSS56 DLGAP3 KIAA1841 ARV1 DDX46 XRCC6BP1 PGA4 DCAF8 FAM200B PHF14 XK PBX4 MFSD4 LRRC6 ARMC9 CYB5D2 KBTBD12 ADAMTSL5 ANKS3 ZER1 PHYHD1 CCHCR1 C11ORF1 VWA3A PLAC4 SLA2 EFCAB4B C10ORF35 FAM196A ZSCAN5A ZSWIM7 SEC61A2 TMIGD2 TRIM58 C9ORF174 HYAL3 EPB49 PRG3 ICAM4 FAM104A C10ORF116 FGFBP2 IDI2 MEF2BNB-MEF2B ARIH2OS GNB5 C14ORF79 GAREML C9ORF89 FAM211B NMUR1 RNF214 C1ORF227 CXORF65 KEL PUS7L SIAH3 KIAA1919 BPIFC CCKBR XG GAPDHS Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in PBMCs at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 AMACR CANT1 GDF15 SEC14L1 VPREB3 HSPA4 LYN GTF2F2 RNF41 XIAP TLE3 RYBP TREM2 UHRF2 MPZL3 QSOX2 CRK HGS HERPUD1 YWHAH MTCH1 HSPA8 RNLS GRB2 NR3C1 SCRN3 TM7SF3 RPS6KA5 C1ORF63 ZNF253 HES1 MCTP2 OMG MYO5B PAWR MBNL2 MDM2 TNFAIP2 TOR1B C15ORF39 HBEGF MBD1 MAP3K11 NDST1 SLC15A3 APH1A LTBR RHOB SYNGR2 SCAMP2 SLC38A7 GAS2L3 RNASE2 MAPK6 DDIT4 LHFPL2 OPN3 IRF5 CTSZ PDSS1 C1QB ADORA3 SCIMP CLTA SLFN11 PADI2 TBL2 CDC45 MAP3K6 GNPDA1 MSC CGREF1 TUFT1 KLF15 ZFP36L2 ABCD2 CRB3 CCNE1 ZBTB42 AGRN WIF1 SP6 PRICKLE1 PYGO2 FGF9 ATF3 IRF8 UMPS PSRC1 RNF26 CLCN5 TMEM164 SDK2 KDM4B TBL1X NUAK2 RBM47 HCLS1 IL10RA GATM GPR15 CD86 SIGLEC1 TREX1 C5ORF28 JPH3 NFKBIE TIFA SOCS1 TLR3 ZNF711 FOS PLTP GRASP DUSP1 ELOVL5 TXNIP NFKBIA SMAGP JUN DCN AMMECR1L ZNF780A HIPK3 CD74 TSC22D3 ITPRIPL2 SLC39A1 HSPH1 JDP2 DNAJB1 MYLIP ARL1 MFHAS1 STARD9 TAGAP KIAA1551 DNAH1 RIMS3 ZSCAN9 KBTBD8 MRC2 HDAC9 ZFP37 NAPSA FAM129C PCBD2 KLHL15 CSRNP1 ZSWIM6 NFKBIZ SH2B3 MSL2 DEPDC7 ALAS1 GMPR2 SDC2 C1ORF74 PCBD1 HOXB7 CXXC5 HSPA1A FAM122B CCDC117 GPR89A NUDT9 USP10 FAM13A PDE4B PARD6A PPM1H YIPF6 RND1 REL MAP3K14 HIST1H3B GRAMD4 EBI3 LAT2 HIST1H1T CELF3 TLR2 ZCCHC2 ETV6 MARS2 TRIM5 RIPK2 MORC3 CXCR5 NCKAP1L BCL11A SNX20 WDFY4 PIKFYVE CCNB1IP1 HIST1H4E CASS4 PRPF39 RP2 PIGL PER1 VPS41 LPGAT1 BBS2 RNF19B LRIF1 BCL10 TRANK1 ARMC2 PKIB CHUK FNIP1 FAM110C LENG9 TAF15 ETS2 FBXW11 ZNF426 GTPBP2 SNN MBD2 NAV1 HEXIM2 SOBP XKRX BANP GAS1 PRKAG2 IL1RAP BCAR3 OSGIN1 UPB1 HIST2H2BF FADS2 ADAM19 TUBB3 FCER1A VPREB1 CD68 C1ORF127 CCSER1 PDE1B IRAK1 PRKCD OLA1 SLC31A1 NAGK AQP9 CARS DOT1L EGLN1 CXCR4 TFEB SYK RYR1 ERP29 CPPED1 RBM22 MCFD2 BHLHE41 ALDH3A2 ABHD5 ZC3H11A MID1IP1 GAB2 NDE1 XPNPEP3 KIAA0247 NIPA2 KIF13A ATP7A SUV39H2 DCAF13 HOXC4 TMCC1 SMS LRRC49 GABRA5 MEF2D TEP1 ULK3 CLTB PLEKHM1 HOXB6 SIRT7 TET3 NFKBID RTN3 PMM2 ATP6V0A2 LUZP1 TTC7A RHBDF1 SLC25A44 VPS37B RPS6KA4 IRAK4 PLN RAB6A IL6R PRCP NFE2L2 SLC7A6 DGKG SLC5A3 ECE1 NAF1 NDUFAF6 CDK19 PDGFB CCNG2 IFT57 ZNF396 LRBA NXPH3 FSD2 FPR3 PAK1 GOLPH3L HK2 CTNS PLD1 RC3H1 ZNF175 UHRF1BP1L ZSCAN25 IL13RA1 GOLGA5 ACSS2 MAP3K2 PPP1R9B PEA15 EYA3 CCDC88A RRM2B KCNIP3 DFFB MET CCNH PRPF38A UBP1 THOC5 TCL1A RCSD1 DSE LIPN PLA2G4B PLCG2 IKBIP SLC39A6 EIF4ENIF1 KLHL18 KCTD5 MTMR9 NEURL4 QKI ZBTB9 ZNF16 RUSC2 ZBTB24 ZFX DNAJB6 ZSWIM4 SKIL FAM173B SYNGR1 KCTD11 MYSM1 FAM43A GXYLT1 ICA1 KIAA0319 CHST11 CABLES2 FAM222A ZMIZ1 CAMSAP2 C3ORF58 SACS OPHN1 TMEM2 GPR135 DTWD2 DENND4A SYT11 KLHL36 DOCK7 FBXL20 ARL10 ERLIN2 C1RL PRLR PLEKHA2 SH3BP5 HIST1H2AK LYSMD3 EAF1 HIC2 SGCB FAN1 LSM14B MED20 KIAA0513 PHAX SH2B2 TTYH2 ADARB1 TUSC1 SESTD1 PWWP2A FAM193A LDLRAD3 SGK223 ARHGAP39 ENOPH1 SSFA2 RNF38 FAM53C GPR180 RPRD1A ZDHHC21 MLL4 PPP2R5E KATNBL1 MKLN1 DDX11 ELFN2 KLHL9 GPD2 ABLIM2 C12ORF44 TCP11L1 AK5 CLASP2 CDKL5 PNMAL2 S100A1 USP46 SNX27 OTOS CMTM1 YRDC FAM175B TRMT61A POLR2D PEX12 ECD FBXO42 FAM131A SLC25A19 ZNF619 TRIM33 BNIPL HOMER3 ZNF709 CNR2 ZNF347 ZNF814 SHISA8 FBXO22 PUS3 LSM11 IGDCC3 BAIAP3 ZCCHC8 TMEM132B LZIC ZNF345 SAYSD1 SAP130 EVC2 C12ORF4 KIAA0226L RNF150 ANGPTL1 TBC1D14 ZMAT1 DFNB31 DNASE2B KCTD21 LDOC1L VPS37A C12ORF61 C12ORF5 GRAMD3 CXORF57 TAS1R3 ZNF429 DLGAP1 LOH12CR1 PCDHGA7 RAB3A SIGLEC6 ZC2HC1C MAMU-DRB5 ATF7IP2 MAMU-DRB1 ZNF813 MAMU-DPA ZNF10 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 IL1B SARS2 CD14 PIGS RIPK1 YIF1A SEPP1 SLC22A18 CUL1 ACSL3 TBX10 ACAA1 FCGR2A ADAM17 VARS TMEM176A CNDP2 TMUB2 TMEM173 PEPD BDKRB1 LILRB1 UBQLN2 MYD88 NEU1 PLEKHA5 MUT NSUN3 TMLHE FAHD1 KLHDC4 UBOX5 ENO1 BCL2L2 FAM114A1 ENTPD3 HES1 NT5E MT1E SMPDL3A CA8 MARCKS ATOX1 NDRG2 S100A2 AGAP1 AIF1 DHRS9 PLA2G15 RELT C1QC ATG16L2 TOR1B HS1BP3 C1QA PNPLA6 TBC1D2B GAA EMILIN2 SPN PROS1 CIC B3GNT7 EIF3B SLC16A3 EHBP1L1 WDR13 HK3 LTBR FBXO6 NCSTN SLC11A1 MYOF C3AR1 SMARCD3 XXYLT1 NOL3 FRRS1 CLCN4 ADAP2 GALNT2 RENBP TMEM150B CTSZ C1QB TNFAIP8L2 GALK1 SLCO4A1 LTA4H G6PC3 CDCA2 CLDN7 FAM20C EPS8 FAM89A HP ALDH4A1 AIMP2 G0S2 CST7 MS4A2 CDKN1C CCL4 BMP2 STK3 IL18RAP VPS9D1 BATF HPGDS CD300C MMP25 OSM SREBF1 MROH1 ZNF687 WDR7 TCF7L1 NFIC FIBP TFCP2 TCF7L2 OSBPL1A TMEM88 CTSC ZCWPW1 MS4A6E SLC16A5 NBEAL2 SBNO2 MAPK13 CDC25C IDO1 NKG7 PLA1A SIRPB1 PYCARD TNFSF14 MS4A7 FAM83D C14ORF80 EMR1 KNTC1 CX3CR1 TRAIP CLEC7A FCER1G CD274 CCR1 IL1RN SUV420H2 OSCAR C5ORF28 PLAC8 CD177 TCIRG1 SOCS3 TIFA LYPD8 SLC7A11 IFI35 TRAFD1 GPR35 HAS1 WARS RTN2 CD59 CAV2 EHD4 PSENEN COASY KLF4 AKR1A1 SGK1 FAM129B ICAM1 ACAT2 NUPR1 TMEM176B CA4 CSF1R SLC39A1 EHD1 FNDC3B FSTL1 MBLAC1 HCK NCF4 FASN FPR2 COL9A2 BEST1 CCM2L PTGER2 RUNDC3B CYTH4 ZNF554 C1ORF233 TOR4A MAFF CDC42EP3 ATRAID CYB561D2 MPV17 HAUS1 ATP6V0D1 PSMB3 DPP3 TSPAN4 CTSO TNFRSF21 NIT2 SNX10 FAM122B AMIGO2 MAD2L2 PLEKHG6 WDR11 GLB1 TRIM72 TRAPPC12 TMEM139 CPNE1 TIFAB FAM129A ATAD2 COL11A1 CENPL DHRS13 TAP2 P2RY14 PRF1 P2RY13 TLR2 ATF6B GSDMD TAPBPL MAP3K8 IL15 DGAT2 PACSIN1 FES ATP6V0D2 GPR137C CASC1 CEACAM8 SFXN3 TESK2 MT1X SUMF1 DMAP1 SCOC ZNF573 GINM1 DBR1 AGBL2 DUSP4 SNX12 RHBDF2 SOD2 FAS MVB12A RNF149 SERPINA1 FCGR3B DYSF PTPN6 RNH1 GZMB COX6C PLEK GPR56 NAV1 P2RY6 HSPA1L GAS1 PTPRE DENND3 IL1RAP ENTPD1 SEMA7A DNM1 ZBTB47 SDC3 CD68 TNFRSF8 IFNAR2 POP4 FUT7 CD300A FGR GK CASP5 TNFRSF1B IFNGR2 NEDD4 ESD STX4 TOM1 PLBD2 EXOC2 PDCD1LG2 CD82 ROBO3 ZNF330 NUDT8 KCNJ15 ALAD CIRBP ALDH3B1 SLC46A2 SLC25A10 TINF2 ZNF701 PDP1 ZNF668 KCNJ2 C2CD4C COMTD1 PAPLN GLI4 PRIMA1 ATP9A MVK FDXR PIM2 ST20 DAPP1 ALPK1 TARP SLC26A8 CC2D1B MDC1 SASH1 GMPPA PSMD2 FDPS TMEM189 UNC45A GPR108 PTPRJ AMPD3 LRP2 LRPAP1 DRD5 DNPEP EWSR1 KDM3A VWA1 TRPM4 DLEC1 TLR5 TEX22 PRR5L ADAMTSL4 LILRA2 SCARF1 DEFB1 TECPR1 ZNF182 CTBS LPCAT2 SLC46A1 TREML2 HRH2 PTGIR ABCA5 TBC1D15 EXOC4 NR1H3 CIAPIN1 SLC29A2 ADRA1D AIFM2 LNX1 TWIST2 H3F3B DUSP12 ACSF2 HDHD3 KRT23 FAM127B USP42 CELSR3 ZC3H4 TTC39B COMMD4 DECR2 N4BP3 PXMP4 MTSS1L ZNF608 LPCAT3 NHLRC3 C9ORF72 GPRIN2 HDDC2 SNX18 EMB LIMK2 MED16 GALE DNAJC25 SLC35F6 ZBTB3 SNX33 C1GALT1C1 ERLIN2 BPHL ATP11C MAMLD1 ADCY9 MPI VPS33A KCNK7 P2RX7 DOCK4 CCNJL JAKMIP2 PIGN CACFD1 PPP2R1B TSPAN17 GABPB2 RABGGTB RFX2 PROSER1 OBFC1 LYSMD4 ZDHHC14 PLLP NSUN2 CCDC51 ATP2B4 BLM PRPF31 CTPS2 INPP5B FTO PGS1 TNFAIP8L3 MFSD8 CCDC97 PVRL2 NUDT22 MED11 GRIN2D IQSEC2 MR1 SPSB2 DIRC2 POLR3F CDC42EP4 SIX5 ZNF777 MPG TARBP1 NAPRT1 MAMDC4 TAZ SYT15 GINS3 CBWD3 TTC30B ZNF416 ZNF689 SLC52A1 SOGA3 RNF141 GDPGP1 PDE8B NAPB ASPRV1 JMJD7 TMEM234 WDR25 SEPN1 TMEM255A ZSCAN5A ROPN1L RSPH3 DAGLB RNF175 C19ORF35 C7ORF29 FAM211B NMUR1 CCBL2 CCDC151 C2ORF62 GPR77 C20ORF197 PCDHGA11 TSKS C7ORF25 CLDN22 HOMEZ EXD3 C6ORF226 CXORF23 ZNF799 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 F2RL1 TM4SF20 HSP90AB1 ZFAND4 WFIKKN1 APC ERGIC1 RCHY1 SAAL1 GOLGA3 NDUFAF2 ATXN3 CENPF HSPB1 BAG3 ERG LARP7 TMEM54 CRISP3 TLE1 CLEC4G USP54 RBM41 PRKAR2A HSPA8 UBFD1 PTK2 LRRC1 CREBL2 ZBTB44 UFC1 RWDD3 CPT1A NXT2 ASB9 ZNF410 OCIAD2 NBEA CEACAM6 CDK2AP1 CCDC30 LSM12 TPT1 COBLL1 RPL38 HIST1H1E HIST2H2AC ZNF460 TCP11L2 RPL24 USP51 GADD45A RPS29 TMIGD3 WDR78 NFIA ZBTB20 FTL PTGER4 ATG4B PLCB2 GIGYF1 BSDC1 LMNA INF2 KIAA1958 DDIT4 RAB13 HADHB PDIA5 CRIP2 TPPP SLC30A4 TFDP2 TRAT1 PHOSPHO1 EBLN2 ABCC5 MMP1 TRAK2 OBSCN TRAK1 AQP10 ELANE CTSG FAM20A HMGA1 LTF JMJD6 SH2D3A NKD2 FGF9 NUCB2 SOX6 MLLT11 PRC1 MGRN1 NUAK2 RAD54L RAD54B APOD NCAPD2 IGJ LANCL3 TNNI3 FABP3 MYL4 PSAT1 PAQR9 SLC4A1 NPRL3 INHBA HSBP1L1 EPHB6 TMCC2 PCBP2 BMPR2 PTGES3 TOX2 SELK HMGN1 BAG1 ADIPOR1 PLVAP TSPAN7 CA2 RPLP0 SPECC1L BTG1 RPL22 KLF9 CETN2 TSC22D3 FHL1 SNRNP48 NDUFA5 CDK16 SEPW1 CHORDC1 CCT3 HSPH1 AQP1 DNAJA1 EIF4A2 CYP2S1 NXF1 FXYD1 AGPAT4 CACYBP ANK1 ARRDC4 DEFA3 C17ORF99 NR4A3 OLFM4 SOCS2 ZNF484 ZNF596 VASN BBC3 YOD1 ZNHIT3 PDLIM1 C11ORF73 BABAM1 TFPT GPR160 STIP1 CCDC58 TMEM230 TOMM34 SPIN1 AHSA1 AMD1 PDCD10 CXXC5 GMNN ST13 HEBP2 GEMIN5 HSPA2 MXI1 CHST6 CCDC117 PLCD4 HSPA4L NUDT9 DNAJA4 FAM13A FKBP4 GRB7 HSPD1 MRPS6 ENC1 PURB MYH7B CLIP2 SLC6A9 GMDS NUP43 EBI3 NAALAD2 CELF3 RASD1 POU2AF1 LY6G6D DERL3 RGS10 HIST1H4E PRPF39 THAP9 OTUD6B C3ORF33 PER1 HIST1H2AM PRTFDC1 LONRF2 TMEM237 ACN9 STARD4 LRIF1 EFHC1 CBX5 TMEM181 NDRG3 RUNDC1 MAP10 RBM34 GMPR ZNF426 CTNNAL1 PMAIP1 NOSTRIN PANX1 CMTM4 SERF2 PRTN3 AKAP11 SLC25A42 ZKSCAN3 ITLN1 SRSF12 NT5DC3 STK17A TUBB3 NR1D1 CGA FAM65C ALPK3 CA1 TEN1 DOT1L RNF11 PSMD5 HAUS8 PPID OTUD1 UBE2F TMEM183A TIGD1 FBLIM1 DENND2A TPM1 ARPC1A C9ORF78 C11ORF80 SMARCB1 TTC23 XRCC2 TRMT2B HOXC4 PTCD2 SETD8 HSD17B1 THBS3 VEZT DDX50 EIF3J TMEM123 TIGD7 CWC15 CCDC17 ADI1 PLK3 PRODH P4HTM CYB561D1 EIF1B NBN NFKBID ARHGEF7 FBXO31 ABLIM3 LRRC32 RBFOX2 KAT2B PDE3B ACSM3 SLC5A3 BFSP2 CRYBA1 ZBTB14 LCORL PIAS4 TMPRSS9 STRC SIPA1L3 HECTD4 FXR1 YAF2 DDX27 ZNF620 SYNJ2 ATG16L1 FAM133B SESN3 BCL2L13 ZNF224 HYPK ITGAE GSTM3 RANBP10 AP3M2 SUCO RANBP1 ALOX12 GCSAM PPP2R3C ERN1 SDCCAG3 SETMAR GEMIN4 CASP10 PRPSAP2 SLC25A20 AHCYL2 BMP8B EIF3L NFRKB RBM33 FOXJ2 GSE1 PXMP2 STXBP6 ISG20L2 CARHSP1 PGAP1 UBN2 SSX2IP FAM43A RSL24D1 ICA1 SLC39A3 DNAAF2 CDR2 ZNF783 GPATCH8 NAA30 SEMA4F SUGP2 NMD3 PDIK1L SNAPC3 PRKAB2 ARL4A SVIP KLHL36 TTLL4 MZT1 PPP2R3A IFT80 SOCS4 RBM12B IKZF5 TYW5 USP37 TRIM45 PCMTD1 PLK4 CCP110 EML6 MMP28 COL8A2 NCDN ZMYND8 FAM109B C2ORF42 KIF24 ZNF215 SPECC1 UBAC1 HEMGN EPB42 TBCEL NUDT4 CR1L ZSWIM1 POU6F1 ARFGAP1 GPR180 PXT1 CAPN3 PPP1R12B C6ORF211 ADCY3 ZNF773 CCDC132 KLHL25 TMED8 CEP41 ZBED3 SLC43A1 CYB5D1 GID4 ACSL6 TUBB2B PRMT7 KIAA1841 LUC7L AZI1 SAG FTSJ2 PTCD1 KLHL7 PGA4 INTS8 METTL12 MED30 NOM1 RRP8 FKRP ZNF343 ZNF174 RIF1 TGFBR3L RUNDC3A SMN2 ARL17A ACVR2B DCLK2 NGRN ZNF490 ZNF329 DNAJC6 C2ORF15 SCMH1 ZNF696 C5ORF4 CDKL1 USP12 GATSL2 CBFA2T3 CDK20 HTRA4 ACTR3B DNASE1L2 PHC1 CEP57L1 CNNM4 PRDM15 NPFF TSTD3 KIAA0391 PRDM5 C5ORF54 ABHD16B ZNF547 MST4 GKAP1 FGFR1OP CCSAP FAM92A1 C10ORF137 CCDC111 HYAL3 SFT2D3 ICAM4 MARCH8 AHSP C11ORF57 C20ORF196 DARC NEK4 C1ORF227 CLEC17A TSPO2 FAM175A PTPDC1 DYRK3 GFOD2 NSUN6 C9ORF153 ZKSCAN4 LRRC24 ZNF114 CA5B ZNF470 CDYL2 ZSCAN16 C11ORF35 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MPHOSPH10 TMPRSS2 CD200R1L NMI KPNB1 CAPN2 DDX58 CXCL10 RIPK1 CACNA1D IFITM1 SEPP1 SLC22A18 CUL1 LAP3 ACSL3 HOOK3 ADA MPZL1 RBCK1 OAS1 MYO7B RDX ST3GAL4 STAT1 TRIM25 IFITM2 EIF2AK2 POR APOBEC3G OASL MOV10 ISG15 LILRB1 NUB1 MX1 CHD1 FAHD1 ACO1 MGAT1 C20ORF27 PSMA2 ENO1 SERPING1 MT2A TNFSF10 IFI27 EXT1 FAM216B S100P MT1E PEAK1 MARCKS APOBEC3A SCIN RGL1 CD300E CCL8 ISG20 AIF1 DHRS9 TMEM109 PLA2G15 UNC93B1 PDIA6 C1QC PARP10 LGALS3BP TOR1B C1QA PTK2B TYMP BST2 B3GNT7 HK1 APOL2 FBXO6 MYOF MILR1 LMO2 TK1 TMEM106A IFI44 CLCN4 ADAP2 LILRB5 MS4A4A IRF5 MAFB CDC6 C1QB SCIMP KPTN EPSTI1 ROGDI GALK1 LTA4H C2 SLFN11 CBR1 EPS8 BATF2 PTPRO SPATS2L LIPA DTL KCNMA1 SLC43A3 MS4A2 S1PR5 STK3 DDX19B SLC2A8 CISH MINPP1 AGRN ATF3 IRF8 FIBP OSBPL1A PSMA3 CTSC MEF2A TNK2 HELZ2 OGFR KLRD1 SLFN13 RSAD2 OAS3 IDO1 IRF7 NKG7 ZBP1 BARD1 SLAMF7 NLRC5 IL18BP PLA1A MS4A7 TAP1 GFI1 GPR84 GZMA CX3CR1 IFIT1 TNFRSF18 CCR5 CLEC7A IFIT3 RTP4 TLR7 OAS2 PHF11 SIGLEC1 XAF1 PSMB8 CD274 APOL6 CXORF21 DHX58 IL1RN TREX1 USP18 CMPK2 IFIT2 IFI16 PLAC8 TIMELESS HERC6 IFIH1 STAT2 PML ADAR GBP2 PARP9 PARP12 GCH1 HSH2D GBP6 IFI35 PARP14 SOCS1 TRIM6 TRAFD1 SAMHD1 PPA1 PARP11 UBE2L6 SP110 TRIL PSME1 DPYSL2 TFG EHD4 PSME2 LY6E IGFBP4 AKR1A1 PSMB10 TMCC3 ICAM1 DTX3L PSMB9 GBP3 FABP5 CST3 MDH2 IFI44L DRAP1 PSMB5 SERPINB9 NUPR1 GIMAP8 SHFM1 DDX3X GIMAP4 SLC39A1 FHAD1 GM2A CD164 ATP5C1 DEK CLEC2B ACTRT3 IL27 CSF1 TRIM22 C21ORF91 PLA2G4C TIPARP PAPD7 ZNFX1 MRPL46 MRPL24 CHMP5 AIFM1 HAUS1 LSM2 DYNLT1 DPP3 UCHL3 PHLDA3 SMARCA5 LYSMD2 TNFRSF21 MCEE PRPF3 MRPL17 PNPT1 SNX10 EBPL NDUFA9 MAD2L2 SDF2L1 RPS6KC1 RUVBL2 PAPD5 APOBEC3C SAMD4A RIPK3 TIFAB GLCE GNB4 ODF3B PCSK1N RDM1 VAMP5 P2RY14 PRF1 SLFN5 TLR2 CASP1 PPM1K IL15RA ZCCHC2 LGALS8 TRIM21 MOCOS GSDMD USP25 FAM46A TRIM5 RBM43 TDRD7 TRIM14 PCGF5 CCRL2 RIPK2 C7ORF49 BATF3 RAB44 VMO1 SFXN3 IFI6 TESK2 DCPS DDX60 SUMF1 APOBEC3B LIG1 RNF19B C19ORF66 TNFSF13B XRN1 MRPS11 SP100 RARRES3 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 SAMD9 GBP1 PAQR8 CORO2A SLC22A4 HES4 OSR2 CDK17 ETV7 MICB BAZ1A PMAIP1 PATL1 NAPA ERAP2 SP140L MDK RHBDF2 WHAMM TMEM62 MOB3C CHSY1 TRIM38 FAS MVB12A FMR1 PIK3AP1 TRIM26 FCGR3B MTX1 RNH1 GZMB PLEK GPR56 ARHGEF3 ARMCX1 P2RY6 PHLDA2 OSGIN1 SDC3 PLSCR1 HRASLS2 CD68 NCOA7 PPM1J CECR1 CCL22 SEMA4D COPS4 POP4 FTSJ1 UBE2J1 TANK IDI1 NAGK SIGLEC14 CARD16 BCL2L14 CASP5 FAM111A ERP29 XPNPEP1 FKBP11 PDCD1LG2 BAK1 PI4K2B RFK NUDT8 LRRK1 CITED2 ALDH3A2 CD33 ALDH3B1 ANXA4 CTNNBL1 RIN2 HIRA PON2 TMEM123 PGPEP1 HAPLN3 PODXL MVK ATP13A1 PIM2 TFEC DAPP1 ALPK1 CACNA1A SLC38A5 CTPS1 SASH1 GMPPA FDPS GLS SNX2 DNPEP KEAP1 GANC SRGAP2 GPC1 KAT2A ADAMTSL4 MKNK1 FPR3 CYP27A1 MRPL40 VCPIP1 SLC46A1 GIMAP1 PTGIR MTHFD1L IL17RC NR1H3 RRBP1 SIAH2 CD2AP H3F3B MSRA TMEM51 HDHD3 CHRNA5 FAM127B USP42 SEC24D DPY19L4 TROVE2 NHLRC3 CNP NOC4L TMEM53 RAD9A PHACTR2 WDR18 RPF2 CPEB3 ARAP2 DOCK7 FUBP3 SNTB1 C1GALT1C1 NT5C3 GIMAP6 P2RX7 DOCK4 RNF138 C4ORF33 MAN1A1 FAM126A EFR3A ZDHHC14 PLLP IDH3A NSUN2 CCDC51 ERO1L MED17 ASPHD2 IQSEC2 MR1 KIAA0368 MICALL2 SLC18B1 FBXO44 GINS3 DHX8 CBWD3 PAK3 RNF170 RSPH9 FTSJD2 C14ORF159 FAM76A HSPA12B IL12RB2 SCLT1 TMEM255A ABHD6 PARP15 APOBEC3H FGFBP2 TMEM110 NMUR1 CCBL2 APTX TIGIT Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UIMC1 GDF15 WFIKKN1 APC ERGIC1 MOGS TOM1L2 MME ZZEF1 RNF41 UHRF2 TMEM39B TUBA4A COL4A4 MEPCE NLRX1 PLB1 SLC16A6 MTCH1 FCGBP DHTKD1 MYNN GNMT CREBL2 ZBTB44 PITPNC1 ARSG DALRD3 SLC25A16 ZNF410 DEDD2 TMEM71 BEND7 HIST1H2BC HOPX COBLL1 RALGPS2 PPL TCP11L2 FAM214A GADD45A TSTD1 FNBP1L ZNF507 TPST1 C2CD2L SLC12A9 PNPLA2 MAPK8IP3 PGD NUMA1 PLCB2 GIGYF1 MYADM BSDC1 PRAM1 ZSWIM8 RHOB STS MGME1 DDIT4 ARHGAP29 TEX2 MICU1 CMTM2 CORO6 NCR3 TPPP SLC25A29 COL18A1 PRDM8 SLC30A4 TGFBR3 PHOSPHO1 EBLN2 CDS2 RMND5A ABCC5 MMP1 TGFBR1 CTSG RARG MYO19 PPP1R37 TPD52L1 ARHGEF16 LAMA5 NKD2 GABARAPL1 DVL1 TECPR2 PHF12 KDM4B TMEM63B RGL2 PLEKHG3 LRCH4 AKT1S1 ERF SOAT2 TNFSF14 HIST1H2AE TKTL1 IGF2BP3 TNNI3 MYL4 COCH CTSK IL1R2 HBB SLC4A1 CLEC4E NPRL3 LRRC4 TMCC2 BTG2 RNF7 GRASP ELOVL5 ADIPOR1 GDPD3 JUN AGER AMMECR1L BTG1 SERPINE2 KLF9 TP53INP1 TSC22D3 FHL1 PEX6 AQP1 FAM134A MKNK2 PSKH1 IVNS1ABP TPRG1L FAM160B2 NXF1 ARRDC4 KDM6B TSPAN18 DEFA3 C17ORF99 PI16 MPZ NR4A3 BPI OLFM4 ZNF484 S100A3 VASN BCORL1 CYP4F3 BBC3 PPP1R15B IRS2 YOD1 MSL2 MMP10 CFL2 GPR160 RAB2B TPRKB CKLF AMD1 ACTR10 MXI1 ADORA2B FAM13A RHPN2 OGT PPM1H LENG8 FOXO4 SRXN1 C7ORF60 HYAL1 PURB DLG4 MCU ITPRIP NUP43 MST1 RASD1 SPNS3 TSPAN33 HIST1H4E LMAN2L CASS4 PRPF39 PELI2 ORM1 C16ORF71 ZNF791 KBTBD7 AMFR SLC35E3 TMEM237 ORC4 MECP2 KPNA6 PIK3R1 FBXO33 ASH1L LPCAT1 B3GALNT1 PXK TM7SF2 CERK AMPD2 PRTN3 SNN ST6GAL1 HEXIM2 RCOR3 ZKSCAN3 SESN2 CHST2 XYLT1 ITLN1 SRSF12 KIAA1549L IL1RL1 ADAM19 FAM101B ADORA2A CGA FAM65C CA1 PLA2G6 ITCH KIT NFATC1 CXCR4 MLLT3 RNF11 ATG9A HAUS8 TMEM43 GALNT1 PPM1A WDPCP DENND2A ABHD12 ABHD5 TPCN1 TTC23 PAQR3 USP36 ATP7A ANKZF1 ZNF8 THBS3 ZCCHC7 GPCPD1 CUL3 TIGD7 TMCC1 CCDC17 PLK3 UNKL P4HTM PRIMA1 MLXIP BTBD9 CYB561D1 FBRSL1 TBC1D7 KLC4 ZFYVE26 HIST2H2BE OLIG1 NFKBID INPP5A ARHGEF7 CHFR SMPD4 SSH1 NISCH VPS37B GUCD1 WBP1L ARAP3 KAT2B HEXIM1 TUBB4A TNFRSF10A CRYBA1 TGFA SUFU USP28 ZBTB18 PNPLA7 CDK19 WNK2 SLC2A12 DPY19L3 CBX7 IFT57 MSRB3 LRSAM1 CYP2D6 SLC19A1 FIS1 RNFT1 ADAMTS13 SESN3 RC3H1 FANCC CD300LB TNFRSF13B S1PR4 BTN2A2 RANBP10 ZBTB17 ZRANB1 MLANA EYA3 ARNT GPSM1 EPOR LPAR2 SDCCAG3 ZNF24 PRPSAP2 AS3MT CYB5R1 KIAA1147 EIF3L SLC4A7 EIF4ENIF1 ATXN2L RBM33 FOXJ2 ZC3H10 ZNF335 IP6K1 ARID3B ABTB2 TMEM55B ZSWIM4 KIF21B FAM173B TUB THSD1 SHB RBFA PGAP1 PTAR1 CPD DCUN1D1 SULF2 FAM43A STK17B MAN1C1 CEP120 KDM5B FAM149B1 CLMP C19ORF47 DSTYK SZT2 PDZD8 ZNF7 ZNF609 SUGP2 HECW2 PRKAB2 KLHL36 FBXL20 NDST2 SLC25A51 PATL2 APPL2 IFT80 PID1 FGGY DDX6 TCF20 ZNF614 KIAA2026 TRIM45 ANO10 EZH1 HIC2 SLC12A4 RELL1 KIF1B EML6 WDR19 COL8A2 COL15A1 PIGM ZMYND8 FAM193A NHLRC2 APBB3 YPEL2 AATK FAM63B SPECC1 NUDT4 ANKRD2 POU6F1 UBE4B PXT1 GPR27 KLC2 MINK1 SNAPC4 KATNBL1 IL8 KLHL22 C3ORF37 HOXA4 MLL2 CNTNAP1 MAP3K15 PQLC2 SLC12A5 GID4 SAP25 DEPDC5 KLHL7 PGA4 METTL12 ZNF236 AGO3 ZNF853 SETD4 MIER2 PLEKHM3 FKRP BNIPL TGFBR3L HOMER3 CNR2 ZNF814 MAPKBP1 PAFAH2 ARL17A ZNF346 AKTIP NGRN ZNF490 ZNF527 PBX4 CPSF4 ZNF696 TMEM231 C5ORF4 ADAMTS18 CDKL1 PION HTRA4 DNASE1L2 ABRA RIC8B ASB14 POMT1 ZER1 NPFF TSTD3 BHLHB9 RIC3 SLC24A1 DEF8 MEGF11 PRDM5 KIAA0226L FGFR1OP C9ORF117 FAM211A SEC61A2 LYSMD1 CCDC111 WDFY2 HYAL3 RBM23 SFT2D3 ICAM4 MARCH8 AHSP CENPBD1 C9ORF106 ZNF10 CLEC17A TSPO2 GFOD2 CA5B ZSCAN2 SLC37A3 ZNF280B C8ORF42 DOCK3 KIAA1107 MTMR7 TSPAN16 SERINC4 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UHRF1 SARS2 PIGS HYOU1 TMPRSS2 ADAMDEC1 SPTAN1 CD200R1L CAPN2 PCK2 DDX58 TUBGCP2 DPEP1 CXCL10 CACNA1D JAKMIP1 IFITM1 SEPP1 SLC22A18 CUL1 ACSL3 ADA F5 ZYG11B OAS1 DNMT1 STAT1 TMEM176A CANX AASS CNDP2 EIF2AK2 POLA2 ITGA4 OASL MOV10 FRMD4B ISG15 CD4 GORASP1 GOLGB1 UBQLN2 REEP6 MX1 UMODL1 NSUN3 TM2D2 KLHDC4 ALDH6A1 ACO1 NAGLU LAS1L SERPING1 CERKL IFI27 EXT1 TTC39A FAM216B SYTL2 MT1E CD180 APOBEC3A OTUD7B RGL1 CD300E ISG20 STIM1 PLA2G15 UNC93B1 PDIA6 C1QC ENPP4 PARP10 LGALS3BP TOR1B RNASEL MICAL1 SLC3A2 CHID1 C1QA SEC24C SPN BST2 ITGAL APOL2 FBXO6 ACLY MYOF PLEKHN1 TUBG1 LPL MYO1E TMEM106A FRRS1 NUF2 IFI44 HMMR CTNND1 RENBP SHROOM1 MAFB CDC6 C1QB KIFC1 SCIMP EPSTI1 SPRY2 GALK1 EIF4G1 SLCO4A1 G6PC3 CDCA2 C2 NAGA EPS8 CDCA3 PTPRO SPATS2L MKI67 SH3PXD2B LIPA S1PR5 CDKN1C MPEG1 CYP4V2 CISH HPGDS TRAPPC9 AGRN CCDC120 WDR7 NFIC ATF3 TCF7L2 CACNA1H CTSC SLC16A5 HELZ2 KLRD1 CYSLTR2 SLFN13 RSAD2 OAS3 KLRC1 IRF7 NKG7 DENND1C ZBP1 BARD1 AGAP2 SLAMF7 IL18BP PLA1A MS4A7 PLD4 C14ORF80 GFI1 GZMA MCM5 CX3CR1 IFIT1 TNFRSF18 CCR5 LAG3 INCENP CCL3L3 RAD51AP1 IFIT3 RTP4 OAS2 C3 SIGLEC1 XAF1 CD274 APOL6 DHX58 TREX1 USP18 CMPK2 IFIT2 IFI16 HERC6 LGMN STAT2 PML GBP2 MCOLN2 PARP12 GBP6 ASAP3 IFI35 PARP14 TRIM6 GPR35 SAMHD1 PARP11 TRIL EHD4 KLF4 LY6E RAMP2 GBP3 GPAM IFI44L IMPAD1 GIMAP8 ARRDC3 GIMAP4 FASN IL27 CSF1 CCND2 RIMS3 KLHL11 E2F6 PLA2G4C BHLHE40 ATRAID CYB561D2 AIFM1 HAUS1 SLC29A1 DPP3 TMEM14A ZW10 SYNCRIP HTATSF1 TNFRSF21 RPS6KA3 NUP93 RPN2 LEO1 MAD2L2 EMC9 PRPF8 WDR11 APOBEC3C SAMD4A HSD17B7 TIFAB HIVEP2 ATAD2 ZBTB2 PIGT P2RY14 NCR1 PRF1 NAGPA SLFN5 IL15RA ZCCHC2 TRIM21 MOCOS TRIM14 RXRG ACAP1 TFRC RAB44 CYP1B1 AARS ZMYND12 SFXN3 IFI6 AFAP1L2 TESK2 MT1X SLC20A1 DDX60 HHAT WDHD1 DMAP1 EIF3A APOBEC3B LIG1 C19ORF66 SCOC MX2 IFIT5 HERC5 DDX60L GBP1 CHD4 ZNF223 RFX7 HES4 OSR2 KLHDC7B RELB ETV7 SEC31A SNX12 RHBDF2 TRIM38 FCGR3B XPO1 PRKCH GZMB GPR56 ARHGEF3 P2RY6 SAMD10 SDC3 KIAA1614 CD68 NCOA7 GZMH PPM1J POLR1A PDE1B IL21R CCL22 DHX36 POP4 EXOSC10 USP33 SIM2 PLBD2 EXOC2 PDCD1LG2 PRKCA PI4K2B ROBO3 ZNF330 SEC23IP NNT IP6K2 EFTUD1 RIN2 HIRA AGPAT3 CCAR1 TMEM123 GABRA5 COMTD1 PGPEP1 SYNE1 SYNM SLC39A13 MVK AMDHD2 ATP13A1 RGL4 TARP HDAC7 CC2D1B MDC1 SASH1 GMPPA PCDH1 TMEM189 UNC45A PELI3 GCLC DNPEP ABI3 CLCN2 GANC PTPN11 VWA1 TRPM4 CTTNBP2 AMOT MIA3 ATG4C TP53BP1 KAT2A PRR5L NRAS ZNF202 ZNF182 WDR41 PTGIR HUWE1 PARP4 NR1H3 CIAPIN1 ABCA6 ADRA1D FAM151A CDK8 FBXO45 NUP205 NUP133 DHDH CCDC134 TMEM51 HDHD3 RFT1 IARS2 MAGED2 RUSC2 C20ORF194 LPIN2 DHCR7 DECR2 LGALSL KIF3C ACVR1 DPY19L4 MTSS1L ANKRD50 NMRK1 HEG1 LPCAT3 SRGAP3 TMX3 IBTK CNP HCFC1 GTF3C1 TMEM53 GPRIN2 HDDC2 TSHZ1 SPATA13 TMEM161A DNAJC25 PFKP SETD1A SLC35F6 RPF2 GOLIM4 VPS13A PALLD ZNF441 TGIF2 FRYL ARAP2 FUBP3 ZSWIM3 PEX13 TM9SF4 PCTP STRIP2 ADCY9 P2RX7 JAKMIP2 CUL5 MAN1A1 PIGN DTWD1 RAD18 ZMYM3 PROSER1 ST7 NSUN2 CTPS2 FTO EXT2 SLC25A53 TNFAIP8L3 HDGFRP2 CCDC97 ADCK4 FAM208A MR1 POLR3F MTMR4 FLYWCH2 MPG C3ORF18 MAMDC4 CHRNB2 EPHX3 UBE3D ARV1 KIAA1429 GINS3 ECD POM121C CBWD3 ZNF416 FUT11 PAK3 AP1G2 SLC52A1 SOGA3 FTSJD2 PDE8B TRIM39 RNF150 SCLT1 SEPN1 TMEM255A ABHD6 PARP15 CDADC1 KLRC3 C1ORF85 C4ORF52 FGFBP2 N6AMT2 SAMD3 EPX NMUR1 L2HGDH CCBL2 C20ORF197 C7ORF25 APTX Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 F2RL1 SPTB UIMC1 PRSS55 ERGIC1 UBXN6 TOM1L2 HIST1H1C MME SAAL1 ESRRA PF4 NDUFAF2 ATXN3 GABARAPL2 TUBA8 FAR2 NLRP6 CLDN15 UHRF2 CRISP3 UBA52 TMEM39B EIF4E2 TST TUBA4A TLE1 SRPK2 CLEC4G MEPCE FAU PLB1 HSPBAP1 MTCH1 HBM PKIG TM7SF3 ZBTB44 SLC25A16 PROZ TMEM186 RWDD3 ALDH8A1 ADK OCIAD2 CDK2AP1 BEND7 SLC15A2 HIST1H2BC HOPX COBLL1 PPL TRIM2 TCP11L2 HIST1H2BK TSTD1 FNBP1L HIST1H2BD SORBS2 PLA2G7 TPST1 CCND1 NEDD4L C2CD2L SLC12A9 PNPLA2 PLCB2 GIGYF1 KCNAB2 PPP1R12C CLTCL1 NET1 DHRS4 RAB20 SHCBP1 STS SPR MGME1 DDIT4 GSTO1 NETO2 SOWAHD TEX2 CMTM2 TPPP SLC25A29 COL18A1 PRDM8 SLC30A4 TFDP2 PHOSPHO1 RMND5A ABCC5 TRAK2 TGFBR1 BMP4 WNT7B LAMA5 WNT5A RAP1A SOX6 KDM4B MGRN1 RGL2 ATG2A AKT1S1 ASF1B APOD HIST1H3D HIST1H2AE TKTL1 TNNI3 MYL4 COCH ALAS2 PAQR9 HBB SLC4A1 TEX40 NPRL3 NAMPT INHBA HSBP1L1 PCBP2 PTGES3 TGM2 ELOVL5 ADIPOR1 TSPAN7 GDPD3 AGER CLDN5 CA2 BTG1 SERPINE2 MYH10 C19ORF43 ISCU CCNI JUND FHL1 FUCA1 TYROBP NDUFV3 S100A16 LIMS2 KLHDC3 AQP1 RBBP4 TNNI2 NXF1 GPX4 BNIP3L DMD ARRDC4 DEFA3 CLIC2 C17ORF99 PI16 MPZ FBXO40 KIAA1551 TNFSF4 UCMA VASN L3MBTL1 BBC3 BRD1 PPP1R15B IRS2 YOD1 TSC22D2 FOXO3 FOSB PDZK1IP1 MMP10 PFDN2 CCDC58 PCBD1 AMD1 SKP1 HEBP2 MXI1 ZNF317 HSPA4L FKBP4 C1ORF226 MNS1 PURB MYH7B FAM46B SMIM1 ZNF211 DNAJB5 ITPRIP GMDS EBI3 MST1 CELF3 BID ZNF296 ZMYND10 TSPAN33 LY6G5B HIST1H4E CASS4 PER1 HIST1H2BG ORM1 ZFP2 AMFR SLC35E3 TMEM237 ACN9 C17ORF67 MECP2 GLIS3 CNNM3 CRIM1 CETP LPCAT1 SRRM2 GMPR NT5DC1 NOSTRIN FAM210B TM7SF2 CERK SERF2 EIF1 SNN HEXIM2 BANP PPTC7 CHST2 XYLT1 CHKA ITLN1 SRSF12 UPB1 DPEP2 ADAM19 TUBB3 FAM101B RASL11B VPREB1 CGA FAM65C ALPK3 CA1 BDKRB2 SUPT4H1 PET100 IFNLR1 DOT1L KIT FAIM CXCR4 RNF11 HAUS8 PPM1A DENND2A ABCB11 CDC42BPB ABHD12 ABHD5 FAM193B TPCN1 PARM1 XRCC2 HOXC4 BCCIP NFYB ARHGAP24 CCNYL1 KCTD7 PRODH P4HTM CYB561D1 FBRSL1 ZFYVE26 HIST2H2BE EIF1B NFKBID DTX4 LRRC32 GUCD1 WBP1L HEXIM1 DGKG ACSM3 CRYBA1 FXN PER2 TDRD6 USP28 LPP ZBTB18 EYA2 CDK19 TNKS1BP1 WNK2 CAMKK2 TRA2A CBX7 IFT57 AK9 MSRB3 ZFAT CYP2D6 SLC19A1 FIS1 EIF2AK3 TAS2R4 IVD STK11 SESN3 BCL2L13 ZCCHC4 USP49 CD300LB TNFRSF13B GPR82 RANBP10 HGD HOXA1 EYA3 PPP2R3C MAPK12 EPOR SDCCAG3 TNFRSF6B RPS4X PRPSAP2 LOXL3 IKBIP KIAA1147 BCL7C EIF3L SLC4A7 RBM33 FOXJ2 ZNF335 LETM2 RHOBTB1 ABTB2 TMEM55B TADA2B GSE1 STXBP6 TUB THSD1 ISG20L2 CSGALNACT1 SHB PGAP1 PTAR1 DCUN1D1 UBN2 SULF2 SSX2IP FAM43A ABHD13 KIAA0319 C19ORF47 VASH2 OSBPL10 RC3H2 KIAA1191 FAM155B CCDC71 HECW2 TTLL7 MED19 ARL4A KLHL36 LMLN PPM1L SLC25A51 MPRIP MZT1 IQCK PATL2 APPL2 PID1 HIST1H3E IKZF5 CLASRP HIC2 PIGX CLEC10A CCNDBP1 DCAF12 RELL1 PCMTD1 COL8A2 COL15A1 ARHGAP42 PODXL2 NHLRC2 STX1A APBB3 RAB11FIP4 GYPA SPECC1 UBAC1 EPB42 NUDT4 ANKRD2 TRIM27 UBE4B STK11IP KAT8 GPR180 PXT1 SLC35E1 MOB1B GATAD2A SLC25A6 PTOV1 MINK1 ARMC10 ADCY3 C3ORF37 POC1B KLHL25 MAP3K15 CD300LD ACSL6 TUBB2B PPAPDC1B SAG SAP25 POLR2D KLHL7 PGA4 ZFP62 PRICKLE4 BNIPL TGFBR3L CNR2 RUNDC3A DCLK2 NGRN TTLL3 C2ORF15 KATNAL1 LBX2 SMTNL1 CDKL1 KAZN HTRA4 DNASE1L2 PRDM15 ZER1 NPFF KRR1 HIST2H2AA4 SLC24A1 MEGF11 PRDM5 EVC2 OR2A7 TMEM66 NFASC ZNF547 GKAP1 FGFR1OP FAM211A PDE6H TTC13 PDE7B WDFY2 MYCL1 C6ORF1 HYAL3 SFT2D3 ICAM4 MARCH8 AHSP ARIH2OS GAREML FLJ44635 C9ORF106 ADGRF3 C9ORF37 C1ORF227 ZNF813 TSPO2 FAM175A PTPDC1 LRRC24 C8ORF42 DOCK3 MTMR7 TMEM86B CXXC11 UTS2D GAS8 ZNF565 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GOT1 SARS2 CCL5 CMA1 TMPRSS2 ADAMDEC1 CISD3 ETFA CXCL10 CACNA1D JAKMIP1 PDZD11 ACAD9 SEPP1 CDHR5 ACSL3 ADA POLA1 CRISP3 PHB2 OAS1 DNMT1 ISYNA1 AASS CD7 PLAT ITGA4 OASL NPM1 MOV10 CD8B FRMD4B STOM CD8A ISG15 PTPN4 EVL REEP6 IL10 MX1 PLEKHA5 NSUN3 KLF12 TASP1 RWDD3 MYO6 ACO1 C20ORF27 MNAT1 LAS1L SERPING1 IFI27 CCDC7 CCL3L1 FAM216B C1ORF21 SYTL2 APOBEC3A CD300E ISG20 HIST1H1D NFIA RPS7 STIM1 ENPP4 LGALS3BP TOR1B SLC3A2 SPN BST2 RGS12 APOL2 FBXO6 MYOF PLEKHN1 CDCA8 TK1 CCNB2 TUBG1 CDKN3 LPL NUF2 IFI44 HMMR ERLIN1 MCM2 KIF2C FADS1 BUB1 CDC6 KIFC1 SPRY2 MCM10 SLCO4A1 CDCA2 TPX2 CEP55 CDCA3 CDC20 HJURP HP LIPA CDC45 DTL TYMS IKZF2 PDGFD CPA3 TMEM182 RUNX3 MS4A2 S1PR5 CDKN1C CRY1 TCN1 CLC PRSS57 CKS1B DDX19B CISH ELANE CTSG SNPH LTF AGRN PLEKHH3 MROH1 WDR7 ATF3 NUCB2 ELP3 FPGS MAPK11 TCF7L2 RGS3 CTSC ARHGAP35 CENPN KLRD1 CYSLTR2 ZAP70 ARHGAP11A RSAD2 E2F8 KLRC1 IRF7 RGS1 NKG7 CD3G ZBP1 KIF22 SLAMF7 GINS2 GIMAP7 SH2D1A MS4A7 CTSW PLD4 GFI1 CXCR6 LCK CRTAM IL2RB GZMA CD3D MCM5 THEMIS CX3CR1 TOX AUNIP SPC25 MELK ZWILCH TNFRSF18 STAT4 CD96 CCR5 TBX21 LAG3 KIAA0101 CCL3L3 UBASH3A RAD51AP1 PTPN7 GPR171 FABP4 MB RTP4 IFIT1B OAS2 SIGLEC1 APOL6 DHX58 PHF19 CHAF1A USP18 CMPK2 IFIT2 IFI16 PAQR9 TRIM10 SLC4A1 DHFR SUCNR1 HERC6 LGMN STAT2 PML GBP2 MCOLN2 PARP12 GBP6 HPSE ASAP3 SAMHD1 PARP11 RTN2 TMCC2 CAV2 LY6E IER3 PLVAP RAMP2 GBP3 FABP5 RBBP7 IFI44L DRAP1 SERPINB9 GIMAP8 GIMAP4 S100A16 AQP1 FHAD1 FSTL1 FASN NDUFA4 NUCKS1 RPS27L DEFA3 NSG1 BPI ADAMTS10 CSF1 OLFM4 CCND2 PLA2G4C SLC14A1 MAGEH1 GIMAP2 GPX3 CYB561D2 MRPL46 HAUS1 SLC29A1 PTTG1 MRPL13 DPP3 IMMP1L CCDC124 TMEM14A TSPAN4 KDELC1 ANKRD39 GTF3C6 SNRPA LEO1 SNRPE MAD2L2 EMC9 FAM117A PAPD5 SKA2 LTC4S HIST1H1A ZNF618 GZMM TIFAB HIVEP2 DIAPH3 GLMN ATAD2 COL11A1 SNAPC2 MRPL47 RPA3 RDM1 SLC6A9 PIGT P2RY14 NCR1 PRF1 PCED1B SLFN5 ZCCHC2 TRIM14 ALG9 RXRG ZCCHC18 PRG2 TFRC RAB44 CDKN2C NUDT1 TXK SFXN3 VNN1 GYPC MCM7 DDX60 WDHD1 APOBEC3B LIG1 PRPS2 NCAPD3 C19ORF66 RARRES3 MX2 IFIT5 HERC5 SEMA3G OSR2 KLHDC7B SIDT1 FCGR3B AZU1 PRTN3 MPO PRKCH GZMB COX6C GPR56 KLRF1 ARHGEF3 GLCCI1 P2RY6 FAM115C SDC3 APOE TMSB15B NCOA7 GZMH LRFN1 CXCL12 CCL22 PRDX2 COPS4 YEATS4 IDI1 BACE1 PDCD1LG2 PRKCA HMBS PI4K2B CCDC115 SLC25A10 RAB3IL1 ZNF430 TMEM123 COMTD1 SYNE1 MVK METRN ATP13A1 RGL4 DNAH7 TARP HDAC7 PLXND1 CC2D1B SLC38A5 ACP2 UROD CTPS1 PDGFRB SASH1 FDPS PCDH1 TMEM189 FDFT1 ABI3 NDUFAF6 CPA6 VWA1 CTTNBP2 MTAP FSIP1 RNF14 PRR5L MRPS22 DEFB1 ZNF182 GIMAP1 PTGIR CLEC2D ABCA5 RANBP10 AP3M2 EXOC4 CYP51A1 NR1H3 MYB AIFM2 MGMT TARBP2 IFRD2 ZNF282 NUP133 DHDH PDHA1 TMEM51 ZNF526 CSPG5 DHCR7 TMEM141 PXMP4 HEG1 ZDHHC12 NOC4L TSHZ1 PHLPP2 HIPK1 PBDC1 OLFM2 DNAJC25 PFKP GOLIM4 PHF13 PALLD ARAP2 SNTB1 GIMAP6 FBXL15 MLLT6 NTPCR JAKMIP2 MAN1A1 RAD18 ADAMTS7 SCUBE1 PPP2R1B TBCK TSPAN2 PDP2 GUF1 PROSER1 HSD11B1L METTL15 XPO7 MRPS28 EPB42 SLC25A53 C11ORF52 FAM208A HAUS3 MR1 CNTROB FBXL14 SSBP4 FLYWCH2 SLC43A1 MYEF2 KIAA1429 GINS3 POM121C TTC30B TTLL11 CHST12 XK PPP2R2B TOMM40L COA1 C14ORF159 RGS9 MORN4 EFCC1 TTLL10 GFRA2 WDR76 IL12RB2 SCLT1 PIFO KLRC3 DEFA1 HYAL3 DCLRE1B PRG3 FGFBP2 SAMD3 OLIG2 EPX FAM211B NMUR1 SIRPG PSMG4 APTX CLNK ANKRD35 CD248 CCDC102A Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FCGRT PRSS55 WFIKKN1 APC VDR ERGIC1 TOM1L2 HIST1H1C ESRRA ZZEF1 GOLGA3 AATF ATXN3 ST14 FURIN ZNF274 FAR2 RNF41 TLE3 NFKB1 UHRF2 SPTBN5 TCN2 TMEM39B KIAA2013 UBTD2 TLE1 CLEC4G SDE2 BRCA1 MEPCE PLB1 HSPBAP1 PI4KB AKAP8L FRMD8 FCGBP PTK2 TM7SF3 RBM39 SLC25A16 ZKSCAN1 CPT1A NXT2 CHMP2B OCIAD2 HIST1H2BC RALGPS2 HIST1H2BK CYBRD1 TSTD1 FNBP1L HIST1H2BD HIST1H4H ZNF507 PLA2G7 TPST1 CCND1 MDM2 RELT C2CD2L SLC12A9 MAN2B1 TMEM127 VPS37C HBEGF H6PD PLCB2 GIGYF1 KHNYN MBD1 ZSWIM8 PPP1R12C DHRS4 C1ORF43 SLC35A5 RAB20 TK2 SHCBP1 STS RNASE2 MGME1 EAF2 ALCAM FKBP5 SERPINB10 CLEC1B HGF PPARGC1B CMTM2 TPPP ZNF830 COL18A1 PRDM8 TUFT1 TRAM1 GADD45G ABCC5 ABCC4 SLC24A4 TGFBR1 CNOT3 FAM20A WNT7B ZNF217 MEF2C SPRY3 FGF9 CEBPB KIAA0556 TRIM8 KDM4B NUAK2 RGL2 HSD11B1 CREG2 APOD FANCD2 SLC29A3 CLEC4A IGF2BP3 CFD CDH26 CD86 COCH IL1R2 TEX40 CLEC4E PTAFR MAB21L3 BMPR2 PLTP RASGRP3 EGFL7 AGER CLDN5 PLIN2 SERPINE2 LAMP2 ISCU LAPTM4A RHOQ EPC2 FUCA1 TYROBP CDIPT RBBP4 TNNI2 CCNL2 NXF1 UPF3A DMD ARRDC4 TSPAN18 NR4A3 FAM167A KIAA1551 SIGLEC9 HDAC9 TLR9 ZNF596 VASN IRS2 IER5L BAMBI TSC22D2 SH2B3 MMP10 NQO1 TAF12 TMEM185B CXXC5 PPP3CA ERO1LB AFTPH HSPA4L ADORA2B FAM13A RHPN2 ZNF322 PPM1H TRAPPC12 C7ORF60 PURB MYH7B HACL1 FAM46B SMIM1 CLIP2 NECAP1 ITPRIP LAT2 BID PDK4 RASD1 ZNF296 WDFY4 DGAT2 ATP6V0D2 HIST1H4E CASS4 SIGLEC10 HIST1H2BG SLC35E3 LRIF1 CCNT1 KCTD12 KIAA1033 MECP2 GLIS3 CNNM3 LIPH CETP LPCAT1 BTK RASL10A CEACAM1 NT5DC1 BLNK CERK SNN RNASET2 HEXIM2 ZNF233 ZNF397 BANP CHST2 IL1RAP ENTPD1 CHKA SEMA7A HIST2H2BF DPEP2 KIAA1549L IL1RL1 ADAM19 FAM65C KLHL14 ACP5 IFNGR1 MTSS1 WDR82 TIRAP HHEX CARS DOT1L NFATC1 SYK NR2C2 PSMD5 TBC1D20 SPG21 HAUS8 SP140 GPN2 NUP153 SEC16A ZDHHC13 GALNT1 FAM192A DENND2A ABCB11 BHLHE41 ATP1B3 ARPC1A ABHD16A CDC42BPB ABHD12 TPCN1 PARM1 NIPA2 USP36 FFAR2 ARHGAP24 USP16 CCNT2 TIGD7 PRIMA1 MLXIP CYB561D1 FBRSL1 ZFYVE26 HIST2H2BE NEXN NFKBID LUZP1 CHFR TCF25 TBC1D9 SUN1 PLEKHM2 SLC25A44 IRAK4 TRIM62 SLC31A2 KPNA4 DGKG CRYBA1 SP1 NFAM1 CLPTM1L PER2 COL4A3BP TDRD6 ZBTB18 CDK19 DPY19L3 CBX7 DDX27 MGAT2 IFT57 ZNF620 RAB32 BANK1 TLR10 RNF130 CTNS RC3H1 ZNF175 SETDB2 USP45 USP49 CD300LB CTBS TNFRSF13B LPCAT2 CLEC9A GPR137B HOXA1 EYA3 PPP2R3C SDCCAG3 USE1 ZNF24 PRPSAP2 TMEM59 LOXL3 CLN5 PLA2G4B AS3MT SLC25A20 CYB5R1 DCBLD2 IKBIP F11R SEL1L3 MFSD1 GBAS ZC3H10 GAPVD1 ZBTB9 GGNBP2 ABTB2 TMEM55B ELMSAN1 GSE1 FAM173B STXBP6 THSD1 ISG20L2 MYSM1 UBN2 SSX2IP TUSC3 FAM43A CEP120 CLMP TMEM104 STAG1 OSBPL10 BTBD3 RC3H2 SNX18 ZNF341 HTRA2 C16ORF72 C11ORF24 INTS12 HECW2 KLHL36 LMLN ATP11A NDST2 HIGD1A TCTN1 SWAP70 PID1 FGGY PECR SIDT2 DGKD SH3BP5 ZNF281 ZNF776 IKZF5 ICOSLG EZH1 TNPO1 PIGX LSM10 RELL1 PCMTD1 WDR19 COL8A2 COL15A1 MESDC1 FAM118B TMEM120A NHSL1 FAM109B SNX30 FAM63B SSFA2 ZNF215 ZNF615 DOLK PCYT1A ANKRD2 UPF3B EBF1 TRIM27 ZSWIM1 POU6F1 CASK STK11IP ZNRF2 MAU2 PHF2 KAT8 SLC35E1 GNG7 UBE2W FCHO2 PTOV1 PAF1 PPP2R5E KATNBL1 SGTB SDCCAG8 DPAGT1 C2CD5 CNTNAP1 PQLC2 CD300LD RAVER2 PPAPDC1B SAG CEPT1 INTS8 STK35 CCDC125 FKRP C6ORF89 TCEA2 ZFP62 NPHP4 IQSEC1 BNIPL CNR2 NGRN ZNF329 NMNAT3 C2ORF15 GJA9 DACH1 CBFA2T3 HTRA4 QTRTD1 ANKRD24 TMEM41A HIST2H2AA4 ZNF860 SCARF2 MEGF11 PRDM5 C10ORF118 TMEM66 KIAA0226L ZNF547 ANGPTL1 FGFR1OP PDE6H WDFY2 MYCL1 CCDC13 RBM23 SFT2D3 CATSPERG C9ORF106 KIAA0146 C9ORF37 PTPDC1 DYRK3 C9ORF153 DOCK3 SERINC4 GLTSCR1L UEVLD NHLRC1 GLT25D1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 TIMM10B RPS27A BCL2L1 SARS2 CMA1 CISD3 CHPF ETFA DPEP1 CXCL10 EPB41 NGDN ACSL3 SPTA1 ADA CRISP3 PHB2 GNGT2 TIMM10 OASL PHB CD8B MOB2 UBFD1 HBM PPIA REEP6 GFER SLC25A39 MRPL35 MDH1 GLO1 NSMCE4A CISD1 RWDD3 MYO6 ENY2 FECH PSMA2 RPS20 PFDN5 RPS17 SDC1 RPL9 IFI27 TTC39A RPL41 RPS15A MT1E PBX1 NDUFB2 RPS3A RPL23 COX6A1 SLC2A1 CKS2 ISG20 RPS29 NFIA RPL11 RPS7 RPL7 RPL27A TOMM40 FKBP8 PDIA4 FBXO6 EXO1 TK1 CCNB2 UBE2C SLC16A1 E2F2 NUF2 HMMR LGALS1 TNFRSF17 MCM2 MRPL15 KIF2C CDK1 KIFC1 SPRY2 MCM10 G6PC3 NME1 TPX2 ANLN CDCA3 CDC20 HJURP TRIP13 OSTC CENPW CDC45 DTL TYMS CPA3 MS4A2 S1PR5 CDKN1C CLC PRSS57 HINT1 CKS1B TRAK2 HINT2 SLC2A8 BATF ELANE CTSG LTF PLEKHH3 SFRP4 ANKRD6 FPGS SOX6 RGS3 PSMA3 KLRD1 CYSLTR2 ZAP70 E2F8 KLRC1 CENPA NKG7 CD3G KIF22 SLAMF7 GINS2 GIMAP7 PLA1A SH2D1A MS4A7 CTSW GFI1 IGJ LCK GZMA ECT2 NUSAP1 CKAP2 CD3D MCM5 CX3CR1 SPC25 CENPM TNFRSF18 CCR5 GZMK LAG3 KIAA0101 RAD51AP1 PTPN7 TNNI3 ALOX15 RTP4 IFIT1B POLE2 CHAF1A CMPK2 PAQR9 SLC4A1 SNCA SUCNR1 SLC39A14 LGALS12 TMCC2 PSME2 TNS1 PSMB10 PLVAP NDUFA3 RPS23 CA2 FABP5 RPL5 H2AFZ SNRPD2 ACAT2 NDUFA13 PSMB6 NDUFS3 ARL6IP4 DNAJC8 DRAP1 ATP5H SHFM1 RGCC SOD1 CRELD2 S100A16 AQP1 MPC2 TUBB2A PSMA6 ANXA1 NDUFA4 POLR2K SUB1 USMG5 GUK1 GLRX5 DBI RPS27L ATP5C1 GPX4 COX14 BNIP3L DEFA3 DUSP8 CSF1 TMEM14B ERMAP CCND2 MAGEH1 DPY30 SNRPG CYB561D2 HAT1 MRPL46 BABAM1 PSMA4 TXNDC17 TMEM208 NDUFAB1 FAM216A MRPL27 MRPS33 EPDR1 HAUS1 SLC29A1 PTTG1 MTX2 DPP3 IMMP1L CCDC124 EBNA1BP2 C11ORF48 LSM7 TMEM14A UQCRQ HRSP12 MRPL32 UQCRH MRPL17 ANKRD39 GTF3C6 C15ORF61 ERH LEO1 HSPE1 SNRPE MAD2L2 EMC9 ETFB MRPL11 RPL34 SDF2L1 MRPL18 C19ORF52 RUVBL2 SKA2 HIST1H4C HIST1H1A ID2 GZMM TIFAB DIAPH3 ATAD2 MCM6 MRPL47 RPA3 PTS SLC6A9 GMDS P2RY14 PRF1 IL15RA RXRG PRG2 TFRC RAB44 CDKN2C NUDT1 GYPC C10ORF32 TMEM56 SNRNP25 MRPS11 RARRES3 TMEM159 UCP2 ZNF223 OSR2 GMPR PMAIP1 NOSTRIN FAM210B BPGM TM7SF2 FBXO7 BLVRB PRTN3 CD52 GZMB COX6C GNLY P2RY6 SLC25A42 FAM115C SDC3 TMSB15B FCER1A KIAA1614 GZMH TAL1 PRDX2 COPS4 PSMD9 PHF5A SAMM50 POLR2H FTSJ1 SNF8 TIMM21 COX11 EXOSC7 IDI1 TIMP3 TFR2 STARD3NL FKBP11 HMBS GDE1 PEX19 C12ORF45 CALCOCO1 COMMD1 CCDC115 SLC25A10 MPST CCS COMMD10 STRA13 RAB3IL1 ZNF668 COMTD1 FAM173A BOLA1 TRAPPC6A SYNM THOC6 SMIM5 RGL4 PPP1R14B KANK2 TIMM13 UROD SIVA1 FDPS PCDH1 TMEM189 PRSS8 PC PLEKHF1 DRD5 FXN CDC34 VWA1 BACE2 FSIP1 ATG4A PRR5L MRPS22 MRPS15 MRPL40 DEFB1 SESN3 PTGIR RANBP10 PSMF1 FFAR3 ALOX12 ADRA1D PIN1 PPP1R1B POC1A IFRD2 CENPO FBXW2 TXNDC9 TMOD1 COX7B HDHD3 JOSD2 VANGL1 CHCHD3 SLC25A38 C20ORF194 DHCR7 DPCD MRPS21 FHDC1 NDUFB8 PDF RAD9A HDDC2 PHLPP2 ALS2 HIPK1 PBDC1 WDR18 SPAG7 CCDC167 DNAJC25 ATPIF1 C14ORF2 PHF13 ZNF585A MRPS14 LSM3 ARL4A HDAC11 MRPL14 MPI PHPT1 ST6GALNAC4 PITHD1 NTPCR TMEM63C LSM6 SSBP3 C9ORF40 C17ORF89 ASCC2 MRPL39 PTPMT1 XPO7 UROS MRPS28 ISCA1 FAM46C EPB42 NUDT4 SDHAF1 STRADB COQ7 C11ORF52 ATP5SL MED11 LSMD1 POC1B KDELR3 MRPL22 TMEM242 FBXL14 FLYWCH2 TSSK3 SLC43A1 LIME1 TUBB2B ARV1 EIF2B3 PGA4 IQCC MALSU1 TIMM8A RUNDC3A XK TOMM40L COA1 SASS6 GFRA2 ZER1 POLR1D ZNF22 AMZ1 KLRC3 TRIM58 PPP2R5B DEFA1 HYAL3 EPB49 PRG3 ICAM4 FGFBP2 C16ORF13 EPX C20ORF196 DARC FAM211B PSMG4 GFOD2 APTX TIGIT CCDC102A NDUFAF5 C5ORF34 ZNF485 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GDF15 CNTRL APC VDR ERGIC1 NEK9 TOM1L2 MPP5 ZZEF1 FURIN TLE3 CEP68 BRD2 SPTBN5 COL4A4 TLE1 MEPCE PLB1 CRTC3 HSPBAP1 MTCH1 ANO6 PLEC RAB11FIP2 ATXN2 SIPA1L1 TM7SF3 SF1 CPT1A ALDH8A1 OCIAD2 SLC15A2 HES1 ECM1 LRRC18 DEPTOR COBLL1 NFAT5 RALGPS2 PPL CDC14B TET2 TSTD1 SETBP1 CEP170 ZBTB20 CCND1 CD24 C2CD2L MBD6 TMEM127 PGD NUMA1 H6PD PLCB2 GAA GIGYF1 CIC PRAM1 ZSWIM8 SLC15A3 APH1A DHRS4 P2RX4 RAB20 TK2 STS RNASE2 MGME1 ALCAM FKBP5 FCRL5 PAPSS1 C16ORF54 TPPP COL18A1 PRDM8 SLC30A4 B4GALT1 TUFT1 ABCC4 OBSCN SLC24A4 TRAK1 ABCD2 WNT7B SEMA4B RARG MEF2C FGF9 MAFK SCAMP4 PACS1 KIAA0556 TRIM8 KDM4B MGRN1 NUAK2 ZNF646 PLEKHG3 SOAT2 SLC29A3 HIST1H2AE TKTL1 IGF2BP3 CDH26 CD86 NOD2 BTG2 FOS SH2B1 SPECC1L AMMECR1L LUC7L3 SERPINE2 MYH10 TM9SF2 HIPK3 EPC2 FUCA1 ZBTB16 CAMTA2 CD36 NXF1 AGPAT4 ARRDC4 KDM6B STARD9 NR4A3 FBXO40 MYCT1 P4HA3 KBTBD8 ZNF484 HDAC9 TLR9 ZNF596 LIMD1 VASN ADRA2A IRF2BPL BAMBI SH2B3 MSL2 MMP10 SDC2 RABL3 CYP20A1 ZNF317 AFTPH PAN2 LENG8 PURB KDM3B MYH7B TP53TG5 FAM46B MTFR1L CTDP1 ITPRIP C20ORF112 CELF3 APOBEC2 PDK4 WDFY4 TSPAN33 DGAT2 LY6G5B CPNE2 SIGLEC10 ZFP2 RBBP5 SMG1 SLC35E3 IFT74 CASC3 SPAG9 MECP2 GLIS3 TNRC6B FBXO33 PAQR8 LPCAT1 RFWD3 SRRM2 CCDC142 ETS2 FBXW11 CPEB2 SLC2A10 CSTB PXK BLNK PHACTR4 CERK CASP8 AKAP11 RCOR3 RAD52 IL1RAP KIAA0040 XYLT1 BACH2 JARID2 SRSF12 ADAM19 GPR3 ALPK3 KLHL14 IFNGR1 SYS1 IFNLR1 ITCH HHEX DPP8 DOT1L MDM4 SOX5 RECK SPEN CXCR4 PSMD5 TBC1D20 HAUS8 SEC16A RNF34 DENND2A CDC42BPB ABHD12 ABHD5 ORAI3 GAB2 TPCN1 ANKRD11 NIPA2 USP36 ATP8B1 XRCC2 HOXC4 RCBTB2 FLCN HELZ THBS3 ARHGAP24 TIGD7 TMCC1 MAP3K3 PRODH MLXIP SMPD3 CYB561D1 TET3 FBRSL1 ZFYVE26 HIST2H2BE NEXN NFKBID INPP5A PRDM2 RHBDF1 SMPD4 DST LRRC32 WBP1L ARAP3 PBRM1 TNFRSF10A GSDMA TRIM62 SLC7A6 DGKG CRYBA1 SP1 NFAM1 SUFU GABPA PIAS4 KMT2C ZBTB18 SIPA1L3 HIP1R CDK19 NF1 ASXL1 CYP3A5 CBX7 DDX27 CYP2D6 ATG16L1 ATG2B FSD2 RNFT1 FBXO32 WWP2 CPQ PGAM5 DNM2 SETDB2 ZNF169 CLEC9A GPR137B NAT1 SLC15A4 POU2F1 SLC23A2 CRAT HOXA1 EYA3 LPAR2 SDCCAG3 MAP3K9 PLA2G4B ARHGEF2 AS3MT SLC25A20 PCDHGA9 F11R KIAA1147 HSD17B12 POGZ ATXN2L SETDB1 RBM33 ZC3H10 PIP5K1A SNX19 MGA TIAM2 EPS15L1 BRPF1 BICD2 ZFX KDM2A ABTB2 TMEM55B GPATCH2L KIAA0753 ELMSAN1 KIF21B FAM173B STXBP6 THSD1 ISG20L2 MYSM1 TMEM135 MANBA LCA5 UBN2 SSX2IP FAM43A PGRMC2 GALC CLMP VASH2 OSBPL10 DSTYK DIDO1 SZT2 ZNF783 BTBD7 ARHGAP12 C16ORF72 TRIO RSPRY1 ZNF609 MON2 C2CD3 CWC25 ZNF75A HECW2 DCLRE1C KLHL36 FBXL20 ZKSCAN2 MPRIP IQCK PATL2 PPP2R3A APPL2 FGGY SIDT2 GDI1 DGKD TCF20 ZFC3H1 SH3BP5 VAV2 RBM12B KIAA2026 IKZF5 EPM2AIP1 ZNF555 ANO10 HIC2 ZNF445 ZMYM1 EML6 COL8A2 COL15A1 PIGM C2ORF88 ZXDC ZMYND8 ZNF652 C8ORF58 FAM109B SERAC1 INVS YPEL2 GNL3L ANKRD2 ZSWIM1 STRN STK11IP SPPL3 GPR180 SLC35E1 ZNF418 PHACTR1 CAPN3 SLC2A13 FCHO2 PPP2R5E ZNF773 MLL2 SAMD4B C2CD5 ABLIM2 TMED8 PQLC2 CYB5D1 SNX27 PPAPDC1B DUSP18 SAP25 ZNF853 MIER2 RRP8 AMY2B FKRP ZFP62 NPHP4 IQSEC1 BNIPL TGFBR3L CNR2 ZNF347 TRIM44 MAPKBP1 ARL17A CDK3 DNAJC14 NGRN PCDHGB6 PBX3 ADAMTS18 MAML3 RCCD1 CBFA2T3 TMEM41A KRR1 TTLL9 ZNF354C SLC24A1 KIAA0226L ABHD16B CLVS1 WWC3 ANGPTL1 WDR55 KIAA0922 FAM92A1 MTCP1 TTC13 WDFY2 C20ORF111 C11ORF30 CCDC36 CCDC13 RBM23 SFT2D3 C9ORF106 KIAA0146 C9ORF37 CLEC17A FAM175A PTPDC1 CA5B KIAA1107 MTMR7 SERINC4 ZNF565 GLTSCR1L NHLRC1 KIAA0825 MARCH1 MTMR8 ZNF235 BBS12 SLC24A6 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 BCL2L1 DPP4 FKBP10 CDK5RAP2 TRIM59 LARP1 SPTAN1 UBXN6 MACF1 EPB41 NDUFAF2 DYNC1H1 NCL SPTA1 POLA1 GPX1 CRISP3 DNMT1 RBM28 TM4SF5 VARS PDE4D MYCBP2 ITGA4 ELK4 STOM CD4 HBM REEP6 TOP2B SPTBN1 FBXO9 LIPT1 NSUN3 DMXL1 SLC25A39 ARHGEF12 CABLES1 UBOX5 FN3K ALDH6A1 RWDD3 MYO6 TRIM37 FECH RCAN3 RPS20 MNAT1 PFDN5 RPS17 LAS1L RPL9 TTC39A RPL41 RPS15A RPS24 SYTL2 PBX1 NDUFB2 RNF152 RPS3A KIAA1324 RPL23 SLC2A1 GADD45A UTRN DYNLRB2 RPS29 WDR78 NFIA RPL11 RPS7 NEDD4L RPS27 RPL27A STIM1 PDCD11 FKBP8 CAD SPN RGS12 ITGAL DDB1 TOP2A GTSE1 SLC16A1 E2F2 FRRS1 MCM2 ASPM DLGAP5 EIF4G1 KIF15 CDCA2 KIF11 TPX2 NCAPH GLDN MKI67 RAPH1 YPEL4 BCL11B LTBP4 SIGIRR IKZF2 CA11 KLRB1 PTGDR2 MS4A2 S1PR5 CDKN1C GATA3 CLC PRSS57 TFDP2 TRAK2 EP400 ELANE CTSG LTF BCL9L CCDC120 IFFO2 SLC7A5 MCCC2 WNT11 CLSTN1 WDR7 SFRP4 BMP2K ANKRD6 FZD4 MAP3K4 HERC2 SOX6 TCF7L2 ZAP70 KLRC1 NKG7 SLAMF7 SH2D1A MS4A7 CTSW PLD4 GFI1 GZMA NUSAP1 CD3D CX3CR1 TNFRSF18 TBX21 LAG3 UBASH3A EOMES TNNI3 ALOX15 MYL4 IFIT1B ALAS2 PAQR9 SLC4A1 SNCA NPRL3 ASAP3 NRIP3 MICALCL PCOLCE2 NAP1L5 AHR TMCC2 ETS1 TNS1 SELK TGM2 PLVAP RAMP2 GATA2 RPS23 CA2 COX7A2 GPAM RPL26 PLEKHG2 S100A16 AQP1 TUBB2A MYEOV2 WNK1 VWF NDUFA4 USMG5 NUCKS1 GLRX5 DBI IGFBP5 PIN4 GPX4 BNIP3L ANK1 DEFA3 CLIC2 CSF1 OLFM4 TMEM14B ERMAP CCND2 RPGRIP1 YOD1 FOXO3 SUPT16H BABAM1 GPR160 ZMAT2 BCOR PDCD10 SNRPE RPL34 MXI1 PRPF8 TMEM245 ZBTB8A WDR11 SKA2 HIST1H4C TTC21B GZMM HIVEP2 ATAD2 ATP5E MRPL47 PTS SLC6A9 GMDS P2RY14 PRF1 PCED1B IKZF3 PRG2 CCDC15 TFRC TESC AARS NUDT1 TSTD2 TTF2 MBNL3 MAN2A1 TMEM56 TPR PET117 EIF3A CBX5 GTF2I UCP2 EIF5B THOC2 PKHD1L1 DUSP4 TMEM57 NOSTRIN FAM210B TRIB2 BPGM TM7SF2 FBXO7 PTGS1 BLVRB TCEB2 PRTN3 R3HDM4 MPO CD52 GZMB COX6C SRSF5 GPR56 CUX2 SLC25A42 CENPV FAM115C ITLN1 TMSB15B SLC16A10 TECTA ADD2 TAL1 PRDX2 ITGA6 GATA1 PSMD9 RIOK3 LARS DICER1 BSG PARP1 SIM2 TIMP3 RNF11 NFATC2 TRAPPC10 ZBTB38 PRKCA HMBS IFT20 TMEM183A PPM1A TPM1 ALAD CALCOCO1 C9ORF78 MPST RAB3IL1 HNRNPUL2 MPHOSPH8 EIF2AK1 MRPL33 HTT WDR81 SYNE1 ENG P4HTM SYNE2 SYNM MVK NCOR2 MADD MDC1 TAF1 PCDH1 PC ACSM3 USP9X SSRP1 WWTR1 ACACA MLLT4 HECTD4 CTTNBP2 BACE2 PCM1 AK9 GPC1 ATG14 PIK3R4 PRR5L CYP27A1 EEF2K PRKDC SESN3 ZNF202 ALDH1L1 MPP2 HUWE1 RANBP10 RRBP1 EPOR NFATC3 RBM38 ANAPC1 IFRD2 DNTT TMOD1 COX7B JOSD2 UBASH3B METAP2 SLC4A7 TNIK USP24 SCAF4 SLC25A38 OSBPL7 MICAL2 ANXA6 MRPS21 FHDC1 NFIX DSC3 DCUN1D1 HEG1 CD109 IBTK PPFIBP1 HCFC1 GTF3C1 ARHGAP21 PHLPP2 HIPK1 PBDC1 DCLRE1A CCDC167 NEK1 SETD1A UBE2O GOLIM4 VPS13A PALLD ZNF585A PAOX ARL4A FRYL CHD3 HDAC11 BAZ1B ESYT1 RNF10 SIN3A FBXL15 RBM19 P2RX7 DCAF12 VPS13C JAKMIP2 MAN1A1 ZNF572 RSBN1 FRMD4A SSBP3 GAB1 PDP2 BRD3 ASCC2 PTPMT1 DBN1 HSD11B1L XPO7 UROS GYPA SPECC1 UBAC1 ISCA1 FAM46C EPB42 TBCEL NUDT4 CR1L EPN2 POLR1E MOB1B RAP2A YLPM1 FAM208A GPR126 WHSC1 ELFN2 CEP164 CNTROB POC1B C5ORF42 ZNF777 TSSK3 AMIGO1 SLC43A1 MYEF2 THBS4 TRRAP PGA4 POM121C KCNAB3 RUNDC3A GCNT2 XK DNAJC6 CCDC136 FBXO18 RGS9 SV2A ZCCHC11 GFRA2 ZER1 ARHGAP22 ZNF423 SLC4A11 FAM196A WDR67 KLRC3 TRIM58 DEFA1 HYAL3 EPB49 PRG3 ICAM4 MARCH8 AHSP FGFBP2 SAMD3 EPX GAREML DARC FAM211B NMUR1 PSMG4 KEL TSPO2 DNAI2 SEPT11 RNF112 SLFN14 RNF212 CRIPAK Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in PBMCs at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves peripheral blood mononuclear cells (PBMCs). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GLA RTN4 IL1B PTEN NMI TBK1 RCHY1 UBC TOR1A ESRRA SLC7A7 GOLGA7 PPT1 ANXA3 ATP6AP2 LYN FURIN ADAM9 ZBTB7B GNG5 UBE2D1 SIRPA ABI1 HMOX1 TREM2 FCGR2A ST3GAL4 ARL6IP6 IFITM2 TLE1 REEP5 HERPUD1 APOBEC3G PEPD PLB1 GNB1 HSPBAP1 AKR7A3 MTCH1 RAB1A PLP2 MYD88 RAB5C MAPK1 NEU1 PGM2 TM7SF3 CRADD FARS2 FBXL3 SCYL1 ELL3 C1ORF63 CEBPD NINJ1 HES1 HIST1H2BC HOPX PAWR HIST1H2BK CYBRD1 SSBP2 PLA2G7 TPST1 MPZL2 ARID5A ARHGEF10L DHRS7 ZDHHC7 MBD1 SLC16A3 EDEM2 UNC50 INF2 RARA HCAR2 LTBR C1ORF43 MILR1 LMO2 C1ORF162 LMNB1 PLBD1 SLC35A5 RAB20 GLRX SCPEP1 MGST1 SPR RNASE2 SEC11A MGME1 DDIT4 TMEM38A MSR1 SERPINB10 MS4A4A MAFG CTSZ LGALS3 FAM89A PRELID1 CD163L1 C16ORF54 CXCR2 PTGS2 KLF10 ZFP36L2 SLC24A4 TGFBR1 BMP4 PGAP2 OSM WNT7B TMEM60 PREB BCL3 CEBPB TNFRSF1A NUAK2 TMEM8A ERF GPR65 IDO1 GNG2 SELPLG CREG2 SIRPB1 TLR1 LILRB4 SLC29A3 CLEC4A TKTL1 HIST4H4 GLIPR1 FCGR2B CCR1 IL1R2 GPR141 IL1RN SOCS3 TREM1 NAMPT TIFA LYPD8 NFIL3 LRRC4 GBP6 NOD2 BASP1 CD59 FTH1 SPTSSA PTGES3 LAMTOR3 SHISA5 FOS SGK1 DUSP1 NFKBIA ATP6V0E1 ITM2B JUNB SH3BGRL DRAM1 GNG10 BTG1 SERPINE2 LAMP2 LITAF PISD TSC22D3 SP3 FUCA1 CHORDC1 IFI30 PIM3 SLC39A1 HSPH1 C19ORF59 JDP2 RAB11A DNAJA1 DNAJB1 ALOX5AP HCK EFHD2 IVNS1ABP GTF2B CD164 FPR2 CACYBP SAMSN1 SLA NR4A3 HSPA6 C16ORF86 KIAA1551 TRIM22 CYTIP ZNF484 S100A3 TP53I11 VASN BBC3 IRF2BPL BAMBI CDC42EP3 PFKFB3 SLC25A33 ZBTB34 SH2B3 UBE2A MOB1A MMP10 TAF12 AMZ2 GMPR2 SDHAF2 TOMM34 RABL3 CKLF SGMS1 TMEM185B AHSA1 PSMA1 AP3S1 HSPA1A RAB1B TSEN34 ARG2 HSPA4L TMEM55A NUDT9 HSD17B11 ADORA2B RHPN2 FKBP4 PARD6A TMEM170B COMP FAM46B CLIP2 CD47 NECAP1 PPP3R1 BEAN1 LAT2 NAALAD2 TNFSF8 TLR2 SELL RIPK2 MORC3 C7ORF49 DGAT2 CNOT8 FPR1 LMAN2L CPNE2 CASS4 PELI2 MNDA C22ORF39 LPGAT1 RFC2 LRIF1 CD58 TMEM140 SAMD9 CASP7 KCTD12 TM6SF1 RCAN1 NT5DC1 RRAGD CSTB B3GALNT1 SOD2 RNF149 SERPINA1 C20ORF24 SRGN MSRB1 SNN RNASET2 CSF2RB SERPINB1 CD53 CALM2 HEXIM2 EVI2B PTPRE IL1RAP TUBB3 CDH13 ALPK3 FCAR IL10RB IFNGR1 CCL22 IRAK1 PLA2G6 SYS1 SUPT4H1 RIT1 TANK FUT7 PILRA SIGLEC5 CD300A STX11 SIGLEC14 RGS19 OSTF1 AQP9 IGF1 HHEX CARS EGLN1 CXCR4 PIAS1 IFNGR2 PELI1 NUDT5 PRKAB1 TXNL1 ADPGK YIPF1 UGP2 SEC22B APMAP PPID PDCD1LG2 CD82 ARPC5 ATG12 RNF13 AKIRIN1 RAB21 STX12 TM9SF1 YIPF4 KCNJ15 ARL8B ATG3 ATP1B3 ARPC1A ASAH1 ARF4 ABHD12 CDC42SE1 ABHD5 C5ORF15 DEGS1 PIGH KCNJ2 ARHGAP24 MARCH7 PRODH PRIMA1 TFEC DAPP1 PROK2 NFKBID PSEN1 FLOT1 HBP1 DTX4 RAF1 LRRC32 TUBB4A TNFRSF10A GSDMA IRAK4 EMC7 SNX2 LRPAP1 CRYGS CLPTM1L TGFA CMBL TDRD6 CYP3A5 MGAT2 CYB5R2 RAB32 RNFT1 RNF130 FPR3 LILRA2 CXCR1 NOTCH4 ZSCAN25 CD300LB CTBS NRBF2 IL13RA1 LPCAT2 PPP2CA GIT2 GPR137B SLC23A2 SLC2A14 RECQL4 PRPSAP2 TMEM59 SDCBP MSRA SPSB1 TPD52L2 DNASE1L1 CLN5 CYB5R4 SLBP SDHC GBAS RNF146 TMEM55B DNAJB6 CHMP7 UBE2E3 FAM49A SULF2 FAM43A QPCT CHST11 VASH2 SNX18 EMB C16ORF72 TMED7 PPM1L ATP11A PDCD5 TBPL1 MED21 PECR SH3BP5 ATP5F1 CHIC2 ZNF281 SMNDC1 ICOSLG MSL1 CCNJL FAM118B CCL15 ANKRD37 AATK SSFA2 PRKCDBP DOLK CADM1 ZNRF2 GPR180 UBE2W SLC2A13 ZNF775 IQSEC2 SC5DL KATNBL1 LMBRD1 HIAT1 JAGN1 KLHL25 RCBTB1 CECR5 PQLC2 ZNF768 CEPT1 MRPL49 ZNF853 MLX DNTTIP1 KBTBD11 AKTIP NGRN NMNAT3 AGK TMEM41A TMEM66 KIAA0226L ABHD16B ZNF547 SEZ6 WDR55 FGFR1OP C12ORF76 C20ORF111 DAGLB C16ORF80 C9ORF106 KIAA0146 C11ORF35 GLTSCR1L MARCH1 ZNF83 FAM200A CCDC149 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FOXRED2 UBQLN3 DCAKD CANT1 IL6 TM6SF2 SLC2A7 ERGIC1 CAPN2 TRIB3 THY1 PKP2 DDX58 CXCL10 ANXA3 TMBIM1 PFKL CUL1 ADAM9 KCNQ1 ACSL3 ZNF274 CLCN6 ABI1 CTNNB1 NFKB1 HMOX1 SERPINE1 TCN2 OAS1 MARK3 ST3GAL4 UBQLNL STAT1 EPB41L3 EIF2AK2 TMEM173 CLCA1 PCSK6 MOV10 ISG15 SRC LILRB1 UBQLN2 SCARB1 MX1 MYD88 SIPA1L1 PCMTD2 MTMR14 METTL7A CDK5RAP1 FECH TMEM86A NAGLU MT2A AK4 ASS1 EXT1 SLC40A1 RPS15A APOBEC3A SCIN CYBRD1 CLCA2 RGL1 SSBP2 DHRS9 SLC25A23 TMEM184B UNC93B1 PRNP PARP10 LGALS3BP TOR1B TMEM127 THBS1 ARHGEF10L TOR3A GSN MYADM TGFBI SH3BP2 APOL2 ITGA5 GRN NCSTN FLVCR2 CYFIP1 SLC16A1 MYO1E IFI44 FLT3 MAPK6 LHFPL2 FH MAFB CD163 EPSTI1 EPHB2 DPYD ARNTL2 RNASE3 UPK3B SLC2A6 CDKN1A ZFP36L1 MARS STK3 SERHL2 MPEG1 HMGA1 SREBF1 TSKU RHOU EDNRB WNT5A SHISA2 ELP3 GOLPH3 RNF26 UBE2Q2 FCN1 SCAMP4 DHX34 TNFRSF1A NUAK2 MEFV SLFN13 RSAD2 OAS3 IRF7 FANCI TLR1 IFIT1 TRAIP FCGR2B BPIFA1 PSAT1 IFIT3 IFIT1B OAS2 CD86 C3 CH25H COCH DHX58 KYNU GPR141 IL1RN USP18 CMPK2 IFIT2 COL3A1 PCDH20 PREP HERC6 IFIH1 STAT2 PML TINAGL1 PARP9 HSH2D HPSE C11ORF85 TRIM6 SAMHD1 C5AR1 GFPT2 WARS BMPR2 THBD ZFP36 IGFBP4 TGM2 EGFL7 DRAM1 MAT2A IFI44L TAPBP HIPK3 DDX3X CD97 TEX261 TNS3 GNS THEMIS2 MARCKSL1 CYP2S1 SLC25A25 FBXO40 NCKIPSD TRIM22 FNDC5 COL20A1 PLA2G4C RADIL FOXK1 ADRA2A TMEM213 DUSP6 NQO1 SEC61A1 EPDR1 PGAM1 TMEM185B TNFRSF21 PNPT1 SEC24B CHTF8 ATP2C1 SOAT1 NCOA4 CADPS2 TRIM72 LRRC3 MN1 SAMD4A SRXN1 RIPK3 DENND5A PCNXL3 GNB4 CDH6 NEDD1 GDAP1 AVIL SLFN5 CSF3R MB21D1 TRIM5 TDRD7 F13A1 AZI2 ANKFY1 SLC16A12 SLC6A4 COL9A3 SLC43A2 RP2 GPR63 DDX60 TFPI2 STARD4 RNF19B MX2 IFIT5 HERC5 SLC47A1 PAQR8 GJB2 YTHDF3 CCDC142 OSR2 CDK17 ZNF426 TICAM1 VAT1 TMEM62 MSRB1 DYSF CSF2RB ARHGEF3 ARMCX1 RALGDS CDC42EP2 LONRF1 IL1RAP OSGIN1 TRIM16L SLC25A32 ITLN1 OLFM1 CXCL14 C6ORF10 NR2E1 SEMA3B MAST1 GNA12 IRAK1 PRKCD TRAF6 RAB35 UBE2J1 RIN3 NADK SIGLEC14 AQP9 UCHL1 NPC1 TNFRSF1B TXNDC5 ARCN1 UBAP1 ADPGK COPA BAK1 OTUD1 SLC35F5 SEC23IP SYN3 SCD5 CITED2 CNPPD1 AHNAK B3GNT2 CLPTM1 CDC42SE1 SLC46A2 NIPA2 RIN2 HIRA REC8 STT3B TMEM123 SLC39A8 HECTD3 SLC39A13 BAIAP2 MYEOV FBXO10 ATP13A1 MFSD12 RNF185 G6PD HIST2H2BE LILRA1 PSEN1 TRPC4AP TTC7A CTPS1 PELO VSIG2 SGPL1 TNFRSF11A NLRP3 CPM NFAM1 MUC2 KEAP1 MEGF9 GANC TXNRD1 MGAT2 NSUN4 SRGAP2 PIK3R4 LRRC59 OR1K1 WDFY1 FPR3 SPHK2 TRPC6 TTI1 ZSCAN32 VCPIP1 SEMA4A IL13RA1 NCAM1 ALDH1L1 HAVCR2 PTGIR SMU1 GJB1 SLC15A4 ACSS2 LIMK1 WSB1 CREB3L1 ALDH1A2 TWIST2 UTP15 MCMBP GEMIN4 TOP3B RFWD2 SLC11A2 HSD3B7 SP2 SLC39A6 GPC4 MFSD1 ARMC8 SEC24D ABTB2 C6ORF223 ACVR1 ENDOD1 MBOAT1 KLHL13 FAM198B LPCAT3 NHLRC3 GPRIN2 PHLPP2 LIMK2 CDK18 A4GALT PPFIBP2 LMF2 PCDHGB5 SNTB1 TMEM117 DR1 ICOSLG ZNF107 HEATR5A MSTO1 DCAF12 GAN GFRA3 TIE1 DES BLOC1S3 NDNF NHSL1 LDLRAD3 SLC17A5 TBC1D24 PSME4 QRICH1 CLEC16A MED17 TOP3A KLHL26 KCNG1 TNFAIP8L3 PVRL2 HIAT1 MAPK1IP1L LMBR1 SGK196 MTMR4 PARK2 KCNA3 CWF19L1 PNMAL2 DUSP3 SNX27 MTPAP SLC5A7 ELMO2 KDM8 TMEM116 MVB12B CBLN3 CLUL1 PCDHGA3 MTM1 ZNF846 ZNF586 FTSJD2 CHRNA3 ADARB2 PDE8B PTPN9 ZKSCAN7 ZNF354C LRCH3 C5ORF22 MEGF11 KCNJ1 SLA2 ASB4 C16ORF89 TMEM255A ABHD6 C22ORF28 EXD2 ZBTB46 PPAPDC2 ZNF429 HIATL1 GPR77 CDYL2 SLC24A6 NPIPL3 KCNMB2 C15ORF55 STARD8 GENE-ORF10 GENE-S GABRR3 C16ORF3 ZNF417 PAGE2B RLBP1 NKX2-8 GENE-N GENE-ORF1AB C10ORF76 GENE-M C16ORF96 TAS1R1 UPRT SS18 HDHD1 LRRC33 DYM C14ORF182 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B TMEM82 GCC2 WFIKKN1 VPREB3 TPRN CENPF VIPR1 BAIAP2L2 ATM TMPRSS11A NT5C IL12RB1 USH1C RBM41 AKAP9 CD8B CD244 H2AFJ VAMP8 SAT2 LRRC61 XPA ARL4D RPL37A TMC5 TSHZ2 UQCR10 KRT4 MAL THRB KIF21A SPRR1A CRCT1 HIST1H4H INPP4B FAM183A TFF1 TMPRSS11B FMO2 RPS7 STMN1 C1QA DDRGK1 TBC1D10C ITPKB EXO1 MYBL2 TOP2A CCNA2 CLSPN TK1 TROAP GTSE1 HMMR CORO2B MZB1 ASPM FADS1 BIRC5 FCRL5 MCM10 KIF11 TPX2 MRPL51 NCAPG BCL11B LTBP4 CD247 CPA3 TPM2 ZNF831 CST7 PRDM8 ZFYVE28 NTRK1 PRSS57 FCRL6 TRAT1 PLCXD1 BAD AVP HINT2 ABCD2 HPGDS FOXM1 SLC26A4 MAF SLC5A8 TCF7 CBLN4 FZD8 F2R PNN SAFB OR2A5 NBEAL2 ZNF865 SMC2 PTPN22 KLRD1 ZAP70 CXCR3 LAT CD6 SIT1 PSTPIP1 CD3G LAX1 SEPT1 AGAP2 CAMK4 CTSW CD5 GFI1 HELLS HCST CXCR6 DEF6 ULBP1 LCK CKAP2 CD3D CCDC88B SPC25 ZWILCH CENPM SGOL1 DEPDC1 TNFRSF18 STAT4 CD96 HMGB2 CD2 LY9 NDC80 TBX21 POLE INCENP DNASE1L3 UBASH3A PTPN7 PON1 FABP4 COX7A1 BEX1 TXLNB PGAM2 DNPH1 CD19 AKNAD1 APOC2 ETS1 TOX2 ID3 GATA2 AGER WBP5 SFTPC ITM2C LUC7L3 RPL22 ARL6IP4 TMEM160 ATP5H FAM189A2 MXD4 NDUFA6 CFDP1 CETN3 TNNI2 MYLPF USMG5 USHBP1 UPF3A CHCHD1 PIN4 TMEM256 ANK1 ESF1 LTA PNLDC1 FAM187B SERPINI1 TET1 C6ORF52 NTNG2 TESPA1 ZNF292 PROC TAF1D ANP32A DPM3 HMGB3 ACIN1 C7ORF55 NKAP PTTG1 TPRKB LSM7 UQCRQ CMC1 HOXB7 C15ORF61 MRPL1 CBX1 HEBP2 BEX2 MORC4 CNFN WFDC3 MNS1 PIK3C2B SPATC1L MMP9 REEP1 SMAD9 CTDP1 TCTEX1D2 BCL2L12 TOMM20L TATDN2 SUSD3 PCED1B CELF3 TNNT3 POU2AF1 PIGZ CCR6 GCHFR SNX20 SSNA1 TRAF3IP3 GPR18 TPGS1 SPIB TNN FCAMR TESC PVRIG CELF6 MCM7 ARID4A SEC62 IFT74 TRHDE CDCA7L ZNF302 ZRANB2 PILRB USP44 CHD4 ZBED6 YY1 CCDC173 XRCC4 CAPN12 RSF1 CTNNAL1 ERAP2 BRI3BP SERF2 PTGS1 COX6C LTB LAIR2 MS4A1 LPIN1 DAPK2 SSTR2 OLFML3 IL1RL1 FAM101B C4ORF26 TCEAL2 PIWIL2 ABCA12 FCRL2 SCUBE3 CR2 CATSPERB CCDC34 CD40LG TNFRSF25 RNF113A GTF2H5 PAX5 NDUFB1 FKBP14 ANKRD18A TBXA2R C19ORF53 GGCT CA6 MPHOSPH8 REV1 CEP63 TEX9 MRPL33 MEGF6 FAM173A PLCXD2 HOXB6 TRAPPC6A FAM174B PIM2 GAPT TARP PPP1R16B SREK1 HEXIM1 PHLDB3 SOD3 GNB3 BFSP2 MMP7 OXT ACTN3 BMX DUOX1 DPEP3 SPINK7 PRSS21 MUC4 ZBTB4 KRT78 CHD6 SMC4 AK9 FAM9C PPAN PGP CPT1B FAM133B BLK FBXO32 CD79A FUT1 TNFRSF13B FLT3LG GPR82 CLEC2D DNAH9 ABCA10 ACSM5 SCGB1D4 HOXB4 BIRC7 RWDD1 LTK TCL1A PLCG1 JOSD2 SLC4A7 GCSAML ZBTB48 C20ORF194 BICD1 MOK KIF21B PAGR1 DNLZ PIF1 ARHGEF19 MPV17L2 MRPS21 S100A7 NCCRP1 LRMP TMEM99 RNPC3 FAT2 FAM171B CCBE1 PAXBP1 RAB27B NAA38 MAGIX NME3 CCDC167 RPL39L TP53I13 SNRPF ATPIF1 LSM5 LPAR5 NAA16 IDNK GRIP2 CHD3 APBB1 SEMA3D MGST2 FCRL1 GRAP MAPK8IP2 C1ORF35 RSBN1 PGM5 CENPB AES WDR60 FAM177A1 MINOS1 ANKRD26 MIR205HG PABPC1L FAM213B METTL13 APOLD1 UPF3B RORA GAR1 DTX1 SDHAF1 CCDC39 ATP5I SREK1IP1 DDX11 LSMD1 CEP164 KIAA1377 TRAF3IP1 C17ORF59 ABHD15 LUC7L CGB AMER1 TAF4 PPP1R35 SCGB2A1 ALDH3B2 GRIP1 ST8SIA1 CTU1 SCML4 CNR2 CCDC122 SMIM4 CCDC181 LRRIQ1 S100A7A C14ORF37 CCDC154 LRRC6 CCDC136 MYADML2 UPF2 RGS9 DNASE1L2 DDX55 ZC3H8 EFCC1 CHCHD5 AMZ1 MORN3 MTG2 PGBD1 EMR3 TMIGD2 C12ORF40 MNF1 RLTPR ICAM4 CHRNA10 C20ORF201 EPX SIRPG C11ORF83 ANKRD35 CRIPAK CCDC149 SSPO PLEKHG4B GUCY2D EFHA2 KIAA1731 RGS13 RHBDL2 C11ORF88 CD1E DYX1C1 PTPN20B C4ORF27 SEPT8 SPINK8 CHRNE C1ORF100 FAM25A PRSS41 DFNB59 TRIM51 ZNF683 C9ORF129 HTR4 FCRL4 CCDC11 LEPREL1 ACER1 MYBPH Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MAOA SLC36A1 F2RL1 ADAMTS1 CANT1 UHRF1 IL6 TCF12 SEC14L1 EGR1 DNAJC11 CAPN2 TRIB3 DDX58 CXCL10 CYP2J2 IFITM1 NDRG1 ACSL3 UBE2D1 MPZL1 OAS1 TUBA1C MYO7B ST3GAL4 UBQLNL CRK STAT1 TRIM25 TRAF3 IFITM2 SFN EIF2AK2 IL22RA1 OASL MOV10 ISG15 SRC UBQLN2 FRMD8 MX1 MYD88 KDR METTL7A SERPING1 CEACAM6 KRT5 TNFSF10 KRT7 ASS1 TM4SF1 IFI27 KRT17 EXT1 RPS15A AQP5 UPK1B METTL7B OSMR APOBEC3A HIST1H2BK SCIN SLC2A1 CYBRD1 RGL1 CD300E GPRC5A CEACAM5 CCL8 ISG20 SLC25A23 GABRP MDM2 TMEM184B UNC93B1 PARP10 LGALS3BP TOR1B THBS1 SHC1 GSN MYADM TYMP APOL2 LTBR SLC38A7 TIMP1 VSIG10L SLC16A1 LDLR TMEM106A IFI44 TDRD9 MS4A4A BUB1 SLC1A3 SCIMP EPSTI1 H1F0 ALOX15B SPATS2L DTL SPTLC2 UPK3B AKAP12 IGFBP3 B4GALT1 CDKN1A TUFT1 ZFP36L1 MARS HMGA1 LAD1 SREBF1 ANXA8 JUP KRT14 SLC7A5 SLC7A1 RHOU COL1A2 EREG CLSTN1 WNT5A ATF3 SHISA2 UBE2Q2 BCL3 FCN1 HELZ2 TAB3 NUAK2 ARHGAP27 SLFN13 RSAD2 OAS3 SLC37A2 IRF7 ZBP1 PLA1A IFIT1 CCR5 PSAT1 IFIT3 RTP4 IFIT1B LRP8 OAS2 C3 PHF11 SIGLEC1 XAF1 APOL6 DHX58 C1R USP18 CMPK2 IFIT2 IFI16 TGM1 PCDH20 HERC6 IFIH1 MLKL STAT2 PML TINAGL1 SOCS3 ADAR NAMPT RASA4 PARP9 PARP12 SAMD9L GCH1 HSH2D NFIL3 PTGES HPSE LIPG IFI35 PARP14 FOSL1 TRIM6 TRAFD1 SAMHD1 PPA1 UBE2L6 ANGPTL4 TLR3 FST WARS EPHA1 PCOLCE2 TTYH3 EHD4 BMPR2 THBD ZFP36 TNS1 SHISA5 LY6E FOS HMGCS1 DTX3L CDC42EP1 IRF9 JUNB DRAM1 VEGFA IFI44L TAPBP ARRDC3 DDX3X GIMAP4 PDPN IGFBP7 NRP1 MARCKSL1 FSCN1 SLC38A2 CLEC2B PLCL1 TRIM22 NACAD PLA2G4C FOXK1 MUC1 DUSP6 CCRN4L FEM1B CSRNP1 MAFF ZNFX1 SEC61A1 PGAM1 AMD1 TNFRSF21 PRPF3 ELOVL7 PNPT1 LRP11 MXD1 ODC1 ADORA2B KHDRBS3 TMEM47 SAMD4A INSIG1 RIPK3 MCU HMGCR KLF3 LRRN4 BTBD11 GNB4 NEDD1 SHROOM4 GRAMD4 FAM57A SLFN5 ETV6 SMOX TOR1AIP2 TRIM21 FAM46A ZC3HAV1 SELL TRIM5 TDRD7 TRIM14 PCGF5 RASD1 AZI2 ANKFY1 SLC16A12 GIMAP1-GIMAP5 CXCL11 SLC43A2 IFI6 CRISPLD2 SLC20A1 DDX60 APOBEC3B TFPI2 SLC25A28 STARD4 RNF19B C19ORF66 MX2 IFIT5 HERC5 TMEM140 SAMD9 GBP1 PPP1R3D CKAP4 GJB2 KRT16 EMP1 HES4 PLK2 KLHDC7B CDK17 ETV7 CHST15 NFE2L3 ZNF426 PMAIP1 TICAM1 NAPA TMEM62 C1S FUT4 TRIM26 MSRB1 DYSF AZU1 R3HDM4 SERPINB1 ADAM10 ARMCX1 KRT6B TRIB1 CDC42EP2 OSGIN1 FAM115C ITLN1 NR4A1 OLFM1 IL1RL1 SDC3 CXCL14 KRT6C CRLF1 KRT6A HRASLS2 C6ORF10 NCOA7 PPM1J CXCL12 MAST1 GNA12 IRAK1 RAB35 IDI1 SIGLEC5 SIGLEC14 BCL2L14 TXNDC5 UBAP1 BAK1 TNFAIP1 PI4K2B SEC23IP MCFD2 KIRREL RAB3IL1 CHST10 RIN2 PTCD2 HIRA REC8 TMEM123 SLC39A8 PPP2R2A P2RY2 MYEOV ATP13A1 MFSD12 TLE4 LILRA1 SYN1 CCDC71L ELK3 SLC38A5 KANK2 PELO SLC25A44 VPS37B SPHK1 SGPL1 TNFRSF11A PLIN3 GCLC DNPEP KEAP1 GANC LIG4 MGAT2 IL6ST SRGAP2 GPC1 KAT2A CMKLR1 FPR3 ATP13A2 UBIAD1 VCPIP1 ULBP2 PTGIR SMU1 OR52H1 ACSS2 SLC23A2 SLC16A2 NHEJ1 TRPM6 ALDH1A2 NUP205 SHMT2 GEMIN4 MAP2K4 TOP3B SLC11A2 HSPA9 TMED3 HSD3B7 KRT23 FLNB KANSL3 KCTD5 NOL6 SEC24D ZBTB39 FGD6 AEN ADM2 LIG3 TMEM135 ENDOD1 RAB15 LY6D UST IFRD1 CNP SLC27A3 PHACTR2 PDE12 FBXO34 USP38 ALOXE3 PPFIBP2 DESI1 ZSCAN20 ATL3 OAF PCTP ZDHHC9 NT5C3 DR1 DCAF12 SCN1B GAN RAB3D NGFR FBXL7 BLOC1S3 SLC35G1 FOXE1 ESYT2 TBC1D24 AATK CADM1 ERO1L SRPR MED17 FAM53C KCNG1 CABP5 ASPHD2 C1GALT1 PVRL2 ATAD1 DIS3 SEMA5A CWF19L1 DUSP3 TRMT61A PTPRG SMUG1 ENHO KIAA1199 FTSJD2 ZNF354C TMEM255A ABHD6 PARP15 C22ORF28 GGT5 OR52B6 GENE-ORF10 C16ORF3 ZNF417 NKX2-8 GENE-N GENE-ORF1AB SS18 KIAA1467 UPK3BL Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 NAALADL1 IGSF8 GCC2 CNTRL NINL WFIKKN1 PRAP1 PFAS CISD3 JAKMIP1 ANKUB1 CLIP4 FBN1 HSPBAP1 AKAP9 SIL1 EVL GPHN ABHD14A VAMP8 INTU SAT2 CACNB4 ASB9 TPSAB1 PFDN5 NBEA TMC5 FAM229B C20ORF85 TSGA10 CGNL1 ALMS1 DEPTOR C9ORF116 SPAG16 USP51 C9ORF24 DYNLRB2 MAPK10 FAM183A MORN5 ACOT13 C2ORF73 AIF1 ACER3 ALOX5 PROS1 GPD1 MARCO TBC1D10C MRC1 CD101 MT1F RAB13 CES1 TNFAIP8L2 PPARG GSTO1 LTA4H SLFN11 SCD LRRC43 CPA3 CHI3L1 TMEM182 STAC AVP PIK3IP1 ABCG1 HPGDS AR HORMAD2 CBLN4 DIXDC1 ERVW-1 SORCS1 MAB21L1 OR2A5 ZNF862 COLEC12 GPR162 LAT QPRT ATP8B4 SEPT1 CLEC5A PPM1N CHIT1 FSBP CCDC88B ARHGDIB RAC2 CENPM SLAMF9 CD96 CD2 LY86 GEN1 PON1 FABP4 COX7A1 ADIPOQ RETN CFD PLIN4 TXLNB CCL17 MB CD19 CLEC4E MMP12 CD177 NMRAL1 CLEC4D RAMP1 INHBA PTPRT NINJ2 APOC2 GPR34 ZNF704 CNGA1 GPR116 TOX2 SEPT4 PLTP CYYR1 NGFRAP1 WBP5 SFTPC S100A4 CRIP1 GPAM CCNI CETN2 FHL1 HADH NDUFA2 SOD1 MPC2 C19ORF59 MXD4 MYEOV2 RTKN2 ALOX5AP FEZ2 VWF TNNI2 MEGF8 USHBP1 UPF3A PIN4 BEX4 SCAND1 TMEM256 GPX4 HIGD2A LST1 LCA5L STARD9 SELM PNLDC1 TAGLN3 TCF23 ALOX12B ADORA1 DNAH1 B3GNT5 GPR111 C6ORF52 SAMD15 TLCD2 PABPC3 SLC25A27 DPM3 C7ORF55 NKAP SLC29A1 C12ORF57 HOXB7 AMIGO2 MORC4 PLEKHH2 CLHC1 WFDC3 MNS1 C15ORF65 VEGFB LHB MAP2 RND1 SMAD9 MEIG1 HSD17B14 FUOM TCTEX1D2 SUSD3 TMEM121 ANKRD55 PCED1B LRRC26 CCDC153 FAM161A GCHFR SNX20 PTGDS TPGS1 ATP6V0D2 LENG1 NID1 VMO1 FCAMR GOLGA6A CLGN GYPC CD1B PSIP1 GMCL1 ARL13B ARID4A LONRF2 IFT74 TRHDE CDCA7L TMEM107 SMIM10 PPP1R9A CCDC173 CEP290 CAPN12 C9ORF43 RRAGD GPR115 SERF2 MMD ALDH2 PTGS1 CDA CD52 COX6C LTB CCDC178 IL17D PPFIA4 CENPV TCEAL2 TMEM95 FCER1A PIWIL2 FCRL2 HPD CCDC34 FFAR4 GTF2H5 IFNLR1 IGF1 BACE1 SIM2 CTSF RYR1 GSTK1 ABCB11 ANKRD18A APOC1 BHLHE41 CCL18 C9ORF16 ATP7A ECHDC2 DYNC2H1 STAU2 FILIP1 HSPB11 TEX9 OBSL1 ATXN1 TMEM91 MATN2 HOXB6 TRAPPC6A KCTD15 METRN POPDC3 GMFG AMOTL1 PPP1R13B MICAL3 HIPK2 NLRC4 SLC14A2 ACSM3 BFSP2 PLEKHF1 OXT ACTN3 PIH1D3 STMND1 BMX LIN7B SERPINI2 PRSS12 ARHGEF37 CHD6 UNC5C AK9 FAM9C ABCA9 FIS1 ADAMTS13 TFPI ATG9B ENPP1 GPR82 CLEC2D DNAH5 DNAH9 ABCA10 TTC36 ABCA6 HAAO MAT1A F12 FAM151A SCGB1D4 HOXB4 BIRC7 LTK ACSF2 MRPL23 TOMM7 GCSAML BICD1 MOK ARHGEF28 PXMP2 DNLZ MAOB RIBC2 CHCHD6 TMEM99 RNPC3 MCOLN3 FAM228B APBB2 TECR SVIL MAGIX NME3 TP53I13 ATPIF1 SCAI NAA16 GRIP2 CCDC171 RASAL1 SSPN BTNL9 SPA17 FGGY NUDT7 GOLGA7B C7ORF57 CCDC146 FRMD4A PGM5 IL17RE DNAH12 WDR60 CCL15 OVOL2 ANKRD26 ANKRD37 YPEL2 UPF3B CSPP1 CCDC39 CROCC GPR124 PROCA1 GPRC5B KIAA1377 NPHP1 EFCAB2 CRYBG3 HAGHL LEPREL2 C1ORF173 CCR10 FAM154B ACRBP PCED1A AZI1 KIAA1598 LRRC71 CGB CAPN9 DNAH2 SEC14L3 IFT27 XRCC6BP1 SCGB2A1 PPP5D1 CCDC125 AMY2B ALDH3B2 TCEA2 TGFBR3L SGSM1 LRRD1 MORN1 CCDC122 D2HGDH CCDC181 LEKR1 C9ORF135 LRRIQ1 SPEF2 C7ORF41 PFN4 CCDC154 LRRC6 TCTEX1D4 UPF2 PPP1R36 DNASE1L2 TTLL10 FAM184A FAM184A CAMK1D YIPF7 GFRA2 FAM212A SLC6A16 VIPR2 IQCA1 C4ORF17 C8ORF47 FER1L6 SNX29 MORN3 C7ORF63 ZMAT1 NME9 DNAH11 FAM211A EMR3 C12ORF40 MNF1 C11ORF75 SYNDIG1 CHRNA10 C20ORF201 C19ORF60 CHRNA9 RTN1 ZNF688 CCDC151 C2ORF62 CLEC17A KIAA0825 SEPT11 CRIPAK SSPO C11ORF88 CD1E DYX1C1 SEPT8 SPINK8 C1ORF100 ZNF683 HTR4 CCDC11 CAPN11 DYDC1 PRR24 C1ORF177 CFAP99 C1ORF168 CCDC37 RIMBP2 AWAT2 SCG3 SH2D4B C2ORF71 CCDC19 CIB3 OR6V1 DNAH6 CD164L2 CCDC67 HSF5 SPINK2 CBY3 MC3R WDR64 DPRX NTN5 OR2A12 LRRC36 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 FOXRED2 SPTB UHRF1 TMEM37 CD34 MALL VDR TRIB3 DDX58 PTCRA PLA2G2D HMOX1 TREM2 TCN2 OAS1 SLC27A4 CTSD FN1 UBQLNL CRK STAT1 TRIM25 EIF2AK2 PLD3 CD7 OASL TAS2R38 ISG15 SRC VSIG4 LNPEP FRMD8 MX1 MYD88 METTL7A CPT1A CDK5RAP1 TMEM86A MGAT1 ISLR ASS1 TM4SF1 IFI27 KRT17 ECM1 ZC3H12D RPS15A AQP5 METTL7B FOPNL CCNO CD180 APOBEC3A CYBRD1 CLCA2 RGL1 CD300E HTRA1 CEACAM5 CCL8 PLA2G7 CEP170 MDM2 TMEM184B ARID5A LSP1 PARP10 LGALS3BP TOR1B TMEM127 GSN MYADM APOL2 ITGA5 GRN SLC38A7 ZNF100 MILR1 SCARB2 NREP SHCBP1 TMEM106A FRRS1 IFI44 FLT3 ADAP2 LHFPL2 MZB1 OPN3 SERPINB10 MS4A4A BUB1 SLC1A3 MAFB SCIMP EPSTI1 HGF CCR2 IGLL5 PADI2 ANLN EPS8 TEX2 CDC20 RNASE3 GNPDA1 CCR3 UPK3B CCR9 MGAT4A DRAXIN PTPRS EPHB1 RUNX2 SLC2A5 MPEG1 TGFBR1 KRT14 CDH3 MEF2C COL1A2 CXCL13 EDNRB LAMP1 WNT5A TBC1D8 MAP2K6 UBE2Q2 SLC24A3 FCN1 HELZ2 NUAK2 RSAD2 OAS3 SLC37A2 CLEC4C IL10RA IRF7 SELPLG FANCI ZBP1 TCF19 CD28 TAP1 PLD4 MS4A6A IGJ PIK3R5 GZMA IFIT1 ITGB7 CCR5 BVES PSAT1 IFIT3 CD84 IFIT1B TLR7 LRP8 SLC7A8 OAS2 CD86 C3 SIGLEC1 XAF1 APOL6 CCR1 CXORF21 DHX58 GPR141 USP18 CMPK2 IFIT2 COL3A1 PREP HERC6 IFIH1 STAT2 SFTPB PML TINAGL1 ADAR RASA4 PARP9 HSH2D KCTD19 HPSE LIPG TRIM6 TRAFD1 SAMHD1 CCL19 GAL3ST4 SLC35F3 THBD LY6E FOS IGFBP4 VEGFA IFI44L TAPBP GIMAP8 HIPK3 ARRDC3 CSF1R GIMAP4 IGFBP7 TCF4 GNS THEMIS2 NRP1 MARCKSL1 CYP2S1 PLCL1 NR4A3 RIMS3 CYTIP TLR9 COL20A1 NAPSA FAM129C PLA2G4C FOXK1 GPR157 ADRA2A SEC61A1 TSPAN4 TNFRSF21 ELOVL7 GNA13 NCOA4 ZMAT3 KHDRBS3 SRPK3 SAMD4A RIPK3 LRRN4 GRAMD4 ADRB3 AVIL SLFN5 SELL TRIM5 F13A1 GRIN2C SLC16A12 FCRLA NCKAP1L DERL3 PIK3CG PACSIN1 FES GIMAP1-GIMAP5 COL9A3 SLC43A2 IFI6 PAQR6 CRISPLD2 FAM171A1 DRD1 SLC20A1 LAMP3 DDX60 LPGAT1 C9ORF91 MX2 IFIT5 HERC5 TMEM140 SAMD9 SLC47A1 GJB2 KLHDC7B CDK17 RELB CHST15 RABGAP1L BTN3A2 IL18R1 RAB8B DYSF AZU1 PRTN3 SNN CSF2RB CCR7 GZMB GNLY ADAM10 CUX2 P2RY6 PDE7A CYP26A1 KRT6B GRAMD1B FADS2 SDC3 ENPP2 KRT6A CDC20B RDH12 CARD11 P2RY8 C6ORF10 NR2E1 PPM1J CXCL12 RHBDL3 CECR1 IL21R GNA12 IRAK1 RAB35 UBE2J1 SIGLEC5 SIGLEC14 AQP9 NPC1 TNFRSF1B ADPGK PLBD2 IFITM10 ADAM22 SLC35A4 SEC23IP MCFD2 CDC42SE1 SLC46A2 GAB2 TPCN1 RAB3IL1 CHST10 POLH PHC3 HIRA REC8 TMEM123 SLC39A8 ATP13A1 MFSD12 RNF185 TLE4 LILRA1 TPP1 SLC38A5 ACP2 CTPS1 RAF1 SLC25A44 NLRP2 SGPL1 RPS6KA4 TNFRSF11A NLRP3 PLIN3 NPR1 CPM CDH15 ABI3 NUP160 KDM6A TDRD6 ENOX1 RNF14 SRGAP2 TPBGL BCL2L11 SLC9A9 SLC19A1 CMKLR1 FPR3 ATP13A2 UBIAD1 SCN9A KCNA5 RC3H1 VCPIP1 ULBP2 TREML2 HAVCR2 PTGIR GIT2 ZDHHC17 SMU1 SLC15A4 ACSS2 SLC23A2 SLC2A14 RRM2B KCNIP3 NUP205 ST8SIA4 TOP3B SH2D3C HSD3B7 MMP17 DSE ANTXR2 SEL1L3 KCTD5 ARHGAP17 SEC24D FGD6 CENPT HES6 CSGALNACT1 HHIPL1 GNA15 VANGL2 SULF2 RAB15 LY6D FAM198B HSPA13 CNP USP38 SNX18 SNTA1 PPFIBP2 SLC35F6 CREB3L2 C11ORF24 PANK3 LPAR5 NDST2 SLC25A51 SLC41A2 GIMAP6 PRKCB FCHSD2 MSTO1 SCN1B PLK4 NGFR DES BLOC1S3 SLC35G1 PALD1 SUSD1 TBC1D24 TANGO2 ADCK1 MPP1 CLEC16A FAM53C KLHL26 CCDC87 KIRREL2 JHDM1D ZNF559 SEMA5A TMEM206 FOXN4 MTPAP GPR114 SLC5A7 TTC24 PLEKHD1 AVL9 CNR2 SHISA8 DLEU7 ZNF586 FTSJD2 CHRNA1 MOXD1 ZNF354C LRCH3 C5ORF22 ARHGAP22 SLA2 MTL5 KIAA0226L HSDL1 TMEM255A PARP15 GGT5 AIRE CYBASC3 OR52B6 GPR77 CDYL2 TIGIT CLNK MARCH1 SLC24A6 C16ORF3 ZNF417 PAGE2B C10ORF76 SS18 ZNF829 NLRP12 MCIN BAI3 ZNF708 KLRF2 PRDM14 IL17REL Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 RPS27A TBCA GCC2 NINL WFIKKN1 PFAS ACE2 TPRN LARP7 SULT1B1 PABPC4 ATP1B1 TST CLIP4 ITM2A AKAP9 GOLGB1 USP7 NOL7 PKIG H2AFJ VAMP8 SAT2 KLF12 UFC1 CABLES1 PFDN5 NBEA ENKUR TMC5 TFF3 TSHZ2 FAM229B C20ORF85 CCDC30 ARL3 ALMS1 TPT1 MUC15 SCGB3A1 RPL6 KIF21A C9ORF116 MAP3K19 PBX1 TOX3 NFIB SPAG16 RPS3A SPRR1A BCAS1 USP51 C9ORF24 CRCT1 DYNLRB2 MAPK10 FAM183A MORN5 ACOT13 C2ORF73 ANK3 RPL7A FMO2 WDR78 RPLP1 RPS7 GPD1 MT1F RAB13 CORO2B UACA CES1 RGS16 LTA4H SLFN11 IFI27L2 LRRC43 CA11 CPA3 NCALD DZANK1 BAD AVP HINT2 HPGDS AR MYH14 CLDN3 NR2F2 CBLN4 SORCS1 CCDC170 CMTM8 FZD7 PWWP2B QPRT APOD CENPM HMGB2 DNASE1L3 PON1 FABP4 RETN BEX1 TXLNB MB EFCAB11 CLEC4E MMP12 RAMP1 INHBA PTPRT APOC2 NDP HSBP1L1 SEPT4 TPPP3 GDPD3 RPS23 NGFRAP1 FBXO16 CRIP1 LIMCH1 RPL22 GSTA3 CCNI CETN2 EID1 FAM189A2 SEPW1 SOD1 DSTN MYLK LBH MBLAC1 NDUFA4 CETN3 MYLPF USHBP1 UPF3A NDUFC2 CHCHD1 SCAND1 TMEM256 HIGD2A S100A13 GJB7 RSPH10B LCA5L SELM PNLDC1 ALOX12B IL13RA2 GPR111 C6ORF52 RSPH4A EDNRA SAMD15 CYP2A13 C1ORF204 PROC BAMBI FAM161B ANP32A PDLIM1 CIB1 C7ORF55 MRPS33 NKAP DLG2 HMGB1 C12ORF57 PTMA CMC1 HMGN3 SCG5 MRPL1 BEX2 HSPE1 AMIGO2 NUDC MRPS6 CNFN CLHC1 WFDC3 MNS1 C15ORF65 MT1H MEIG1 MRPL47 RPA3 TCTEX1D2 TMEM121 GCA RIIAD1 CCDC153 FAM161A GCHFR SPNS3 PTGDS TPGS1 C2ORF40 TNN RASL11A BFSP1 VMO1 FCAMR VNN1 TEX14 SLC51A CLGN AGR3 PSIP1 CCDC68 ARL13B SEC62 IFT74 TRHDE CDCA7L RPL22L1 CHD4 TMEM107 CCDC42B SMIM10 CCDC173 CEP290 CCDC160 LIMA1 CTNNAL1 GRAMD1C GPR115 CBR3 SERF2 ALDH2 PTGS1 RPS6 GRAMD2 IL17D TMEM255B TCEAL2 TMEM95 PIWIL2 RSPH1 HPD CCDC34 FFAR4 FCN3 GTF2H5 IGF1 NDUFB1 COX19 SPDYC GSTK1 ABCB11 ANKRD18A AIG1 CSRP2 TSPAN1 DYNC2H1 KTN1 FILIP1 HSPB11 TEX9 MRPL33 TMEM91 HOXB6 MARCH4 NOXO1 KCTD15 METRN PIM2 CDR1 AMOTL1 PPP1R13B MICAL3 PDGFA CST6 GRK5 OXT PIH1D3 STMND1 BMX CMBL TMC1 RNF183 SPINK7 ZBBX SERPINI2 ZBTB4 PRSS12 MLLT4 FXYD3 FANK1 AK9 FAM9C ARHGEF38 FIS1 CPT1B HYPK ENPP1 GPR82 DNAH5 ABCA5 LTBP1 DNAH9 TTC36 SCGB1D4 BIRC7 PIH1D2 PRDX6 ACSF2 DYNLRB1 TOMM7 GCSAML MOK PACSIN3 DNLZ MAOB RIBC2 MRPS21 TLL2 NFIX LCA5 TMEM99 ZBTB7C HEG1 FAM228B IGF2BP2 CCBE1 TECR CCDC96 SVIL MACROD1 MAGIX NME3 ATPIF1 BTNL9 ZC3H13 SPA17 SEMA3D ACADL ECI2 HIST3H2A MAPK8IP2 C7ORF57 SPAG17 CCDC146 VWA5B2 PGM5 C21ORF59 AES DNAH12 WDR60 FAM177A1 CCL15 MINOS1 ANKRD26 ANKRD37 MIR205HG HSD11B1L UPF3B TNXB CSPP1 FAM47E COA5 C11ORF52 MAP9 CCDC39 C16ORF55 POLR2I LSMD1 GPR124 CCDC103 TTC25 KIAA1377 NPHP1 TRAF3IP1 EFCAB2 CCDC176 CRYBG3 HAGHL C1ORF173 CLIC6 FAM154B FAM204A ODF2L PCDP1 RAB17 LUC7L CGB CAPN9 SEC14L3 IFT27 SCGB2A1 WDR66 AMY2B ALDH3B2 CXXC4 MORN1 CCDC122 FBXO15 CDK3 CCDC181 AK7 RSPH9 CALML4 C9ORF135 LRRIQ1 SPEF2 S100A7A C7ORF41 PFN4 FBP2 C14ORF37 PACRG CCDC154 LRRC6 ATP5S TCTEX1D4 FAM184A FAM184A TNR NPFF ALS2CR12 SLC6A16 CHCHD5 IQCA1 DYDC2 C8ORF47 C5ORF38 MORN3 C7ORF63 ZMAT1 CCDC148 CCDC33 C1ORF192 NME9 C5ORF49 WDR16 WDR96 DNAH11 IQCG FAM81B HDGFRP3 MS4A8B C12ORF40 MNF1 C9ORF174 IRX3 C20ORF201 CC2D2A C2ORF62 CCDC149 SSPO PLEKHG4B RGS13 RHBDL2 C11ORF88 CD1E DYX1C1 PTPN20B C4ORF27 SPINK8 C1ORF100 ZNF683 HTR4 CCDC11 DYDC1 C1ORF168 AWAT2 SCG3 CCDC19 CIB3 OR6V1 CD164L2 SPINK2 CBY3 MC3R DPRX LRRC36 CCDC113 WBSCR28 MAK CAPS2 KIAA1407 TTC16 C9ORF9 MORN2 GAS2L2 SMKR1 CA10 EFHB TTC40 SPATS1 C1ORF228 CCDC164 SAPCD1 WDR52 ACYP1 DNAJB13 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MAOA CANT1 UHRF1 CAPN5 TM6SF2 TMPRSS2 MALL SPINK1 CHPF ICOS NPC1L1 ADAM9 ACSL3 SNX31 CALM3 TCN2 OAS1 SLC27A4 DMBT1 TLE1 SFN MFGE8 PLD3 CLCA1 PTGER1 CD7 PGLYRP3 AKR7A3 VSIG4 FRMD8 MXRA8 PCMTD2 TM7SF3 METTL7A CD55 CAV1 CEACAM6 KRT5 CP SDC1 CXCL6 ITGA2 TGFB2 AK4 NT5DC2 KRT7 HIST1H2AL ASS1 MSMB TM4SF1 KRT4 KRT17 IL33 RPS15A AQP5 RAI14 UPK1B KLK11 FOPNL CCNO TNS4 DSG2 TP63 HIST1H2BK SCIN CYBRD1 SEMA3A CLCA2 GPRC5A HTRA1 CEACAM5 GABRP TMEM184B MPZL2 GSN PLK1 TIMP1 PYCR1 TOP2A CDCA8 CCNA2 CCNB2 UBE2C NREP NEK2 SHCBP1 NUF2 DEPDC1B CDCA5 IGFBP2 KNSTRN AURKA DLGAP5 BUB1 RRM2 CDK1 BIRC5 ORC1 KIFC1 SAPCD2 H1F0 HGF SPRY2 KIF15 SMTN KIF11 BRCA2 TPX2 ALOX15B CCNB1 PADI2 ANLN NCAPH CDC20 KIF23 SKA1 TTK MKI67 KIF20A DTL RNASE3 UPK3B MYH11 PTPRS YPEL1 S1PR5 IGFBP3 BMP7 SERPINH1 ELANE B3GNT9 HMGA1 FOXM1 LTF LAD1 LYPD3 GJB3 FGFBP1 GPR87 CBLC ANXA8 ENTPD2 KRT14 C1ORF106 SULT2B1 SERINC2 CDH3 WNT4 COL1A2 WNT8B ALPL WNT2B WNT5A SHISA2 MAPK11 KRT13 TBC1D8 RNF26 FZD9 UBE2Q2 DACT2 TRPV6 SCAMP4 MBOAT7 C11ORF82 RSAD2 UBE2T GSG2 ESCO2 FANCI PLA1A C17ORF53 CHAF1B PARPBP FAM83D IGJ GZMA ECT2 LANCL3 NUSAP1 PBK IFIT1 RACGAP1 MELK CCNF RAD51AP1 BPIFA1 GSTA5 ALOX15 PSAT1 CDT1 OAS2 C3 GINS1 CHAF1A CMPK2 KIF18A ALAS2 MDFI COL3A1 DHFR PREP HERC6 CCDC129 TINAGL1 PTGES HPSE LIPG ANGPTL4 ITGA8 EPHA1 CALML3 SLC3A1 SLC6A15 CAV2 FOS SPARC CDC42EP1 SMAGP NPNT VEGFA IFI44L TAPBP IHH ARRDC3 S100A16 PDPN IGFBP7 KIAA1462 MARCKSL1 PI16 SLC22A14 SPOCK3 NSG1 FUT2 AKR1E2 SPDYA NAPSA RADIL NPDC1 MUC1 GPR157 ADRA2A TMEM213 C1ORF233 PGAM1 GALNT7 SMIM6 TNFRSF21 EPHA7 HSPA2 SOAT1 ADORA2B E2F7 DQX1 ID1 MN1 COL7A1 MCU IP6K3 PRRX2 DOK4 DIAPH3 OTX2 LRRN4 ZCCHC12 PCYOX1L ELOVL4 ARHGDIG GMDS GRAMD4 ANXA10 FAM57A AVIL SLFN5 RASD1 SLC16A12 DERL3 GIMAP1-GIMAP5 SLC6A4 COL9A3 CYS1 RNF182 PCSK9 SLC43A2 IFI6 FAM171A1 FAM111B DDX60 IDH2 MX2 GJB2 ACOT7 LPCAT1 IGFBP1 KRT16 OSR2 NFE2L3 TMEM62 C1S DYSF AZU1 PRTN3 GZMB GNLY ADD3 KRT6B FHL2 FADS2 RTN4RL2 ITGB3 CD70 CXCL14 DSC2 LAMA3 KRT6C ITGB6 CSTL1 CRLF1 KRT6A CDC20B RDH12 KRT24 NR2E1 B3GNT6 SLC6A14 CGA CXCL12 RHBDL3 MAST1 LPO TYRO3 SIGLEC14 TXNDC5 LDHC WIPI1 TBCCD1 VSIG1 C5ORF15 SLC46A2 SLC25A10 CHST4 SUV39H1 CHST10 POLH REC8 SLC39A8 CDH4 DLL4 P2RY2 GAL NECAB2 SYN1 SLC38A5 DKK3 VSIG2 SPHK1 SLC52A3 PRSS8 TNFRSF11A PLIN3 MPDZ SLC22A3 ENOX1 FBXO43 NOTCH3 GPC1 EVA1A FPR3 BHMT NDUFA4L2 SCARA3 ULBP2 PTGIR SMU1 GJB1 SLC16A2 CREB3L1 TRPM6 PPP1R1B POC1A TMED3 HSD3B7 NIPSNAP1 SEC24D SFXN2 CENPT HES6 ZP3 LOXL4 VANGL2 FAT2 SULF2 CPE PADI3 LY6D LPCAT3 CLDN12 IGFBPL1 GPRIN2 MELTF VGLL1 PPFIBP2 PADI1 GPR161 OAF PCTP EHD3 PCDH19 DCAF12 GAN RAB3D PLK4 DNAJC10 HYLS1 MATN1 LOXL1 RBP1 BLOC1S3 SLC35G1 ALDH18A1 YBX2 FOXE1 C16ORF95 TBC1D24 ADCK1 RDH10 GNG4 TIGD3 ASPHD2 LEFTY2 CCDC87 PVRL2 MEIS3 GPR126 SYNC SGK196 SLC22A31 SEMA5A SLC43A1 FOXN4 EPHX3 MTPAP SLC5A7 MUC12 BNIPL DACT3 SHISA8 DLEU7 RNF39 BAIAP3 FIBCD1 MFAP2 IL20RA ENHO CHRNA3 CLDN9 TMEM200C MOXD1 HENMT1 SYT5 IL12RB2 ZNF354C LAMB4 MTL5 ATP2B3 ABHD6 C7ORF10 GRAMD3 CCKBR CDYL2 C16ORF3 PAGE2B NKX2-8 C10ORF76 SS18 LEPREL1 KIAA1467 UPK3BL MCIN CALY GAST CNIH2 TMEM190 GRID2IP CRTAC1 OR6B2 SMIM18 MYO3B ZNF391 ALPP CRABP1 C8ORF48 ZNF879 TEX33 NXF3 FAM178B SLC38A8 GRIN3B RTP1 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B RSRC2 IGSF8 GCC2 CNTRL WFIKKN1 VCAM1 PFAS CISD3 KPNB1 VPREB3 ACE2 GPT ING5 TPRN SLFNL1 LRRC66 TTN SULT1B1 PABPC4 CLIP4 CSNK2A2 MEPCE AKAP9 NOL7 INTU SAT2 CACNB4 ELL3 TPSAB1 PFDN5 ARL4D CYP2F1 TMC5 TFF3 FRK CGNL1 ALMS1 NEK10 KIF21A FMN1 MAPK10 ANK3 AIF1 FMO2 ATP10A ENPP4 STEAP3 C1QA HBEGF DDRGK1 GPD1 ITPKB MRC1 MT1F RAB13 PDGFC TNFAIP8L2 FCRL5 GSTO1 LTA4H SLFN11 B4GALNT3 LRRC43 CPA3 KLRG1 PER3 KLRB1 PDZD4 STAC HPGDS AR JAG2 CLDN3 CBLN4 DIXDC1 JAG1 PNN TCF7L2 SORCS1 SAFB MAB21L1 OR2A5 PTPRU FZD7 PWWP2B KIF13B CYHR1 TNK2 ZNF862 COLEC12 GPR162 CLEC5A ULBP1 PPM1N CHIT1 CCDC88B CLEC4A LY86 GEN1 PON1 FABP4 ADIPOQ RETN TNNI3 KCNA1 TXLNB CCL17 CLEC6A CD19 CLEC4E MMP12 CLEC4D DCDC5 RAMP1 JPH3 INHBA PTPRT NINJ2 APOC2 ATP13A4 ZNF704 TOX2 CYYR1 GATA2 NGFRAP1 WBP5 GPAM LUC7L3 LIMCH1 ARL6IP4 NUPR1 FHL1 RGCC FAM189A2 BMS1 MPC2 C19ORF59 MBLAC1 CDK11A YTHDC1 MEGF8 USHBP1 UPF3A SCAND1 LTA LCA5L STARD9 PNLDC1 SLC5A10 EGR2 MBP TCF23 DNAH1 C6ORF52 EDNRA ZNF292 C17ORF96 IRS2 TAF1D ANP32A DPM3 MMP10 ACIN1 PFDN2 NKAP HOXB7 HSPE1 AMIGO2 PLEKHH2 ARGLU1 MNS1 SMAD9 SFSWAP F10 TMEM121 ANKRD55 TNNT3 GCA DLL1 CCDC153 CCDC78 PIGZ CCR6 GCHFR SNX20 PTGDS TCAP BATF3 TPGS1 NID1 FCAMR GPRASP1 PRPF38B GYPC PNKP ARL13B SEC62 IFT74 TRHDE CDCA7L PILRB CHD4 KIF1A SMIM10 EIF5B ATRX CCDC173 CEP290 PNISR RSF1 TRPV1 SRRM2 RBM34 RRAGD ERAP2 CBR3 FMR1 ENO2 SERF2 ALDH2 PTGS1 FOLR3 LAIR2 SON MS4A1 HRH1 IL17D FJX1 CLK1 TCEAL2 FCER1A CADPS LPPR4 HPD PRUNE2 FFAR4 C4A RANBP2 IFNLR1 ZDHHC11 IGF1 PAX5 IPO8 MAPKAPK2 AIG1 CDC42BPB C6ORF62 CCL18 ANKRD11 USP36 MPHOSPH8 TSPAN1 ETAA1 HSD17B1 DYNC2H1 REV1 RBP4 RBBP6 ARHGAP24 FILIP1 ZFP28 WBP4 TEX9 ATXN1 TEP1 TMEM91 MATN2 HOXB6 MARCH4 METRN SMIM5 PIM2 RTN3 CDR1 RNMT EPC1 LUZP1 AMOTL1 PPP1R13B TSPYL2 MICAL3 SASH1 ITPR1 SREK1 HIPK2 PDGFA ADRB1 BFSP2 OXT ZBED5 PLXNB1 LIN7B SERPINI2 PRSS21 ZBTB4 PRSS12 MLLT4 ARHGEF37 CHD6 INHBB ASXL1 DLEC1 TRA2A AK9 FAM9C ARHGEF38 SYNJ2 FIS1 WDFY3 CPT1B FAM133B BLK ADAMTS13 CD22 RSBN1L ENPP1 GPR82 EXOC3L4 DNAH9 ABCA10 TTC36 ABCA6 MAT1A FAM151A SCGB1D4 BIRC7 TEF TCL1A TOMM7 GCSAML SRFBP1 MOK ARHGEF28 DNLZ TBC1D5 RNPC3 ADAM23 HEG1 PHIP FAM228B IGF2BP2 ZC3H6 ZDBF2 ZBTB40 PAXBP1 SVIL MAGIX NME3 BAZ2B PCF11 TP53I13 NAA16 GRIP2 CPEB4 JOSD1 BTNL9 ZC3H13 SEMA3D RUFY4 MGST2 ACADL FCRL1 RBM25 PRPF4B GOLGA7B MSL1 MLLT6 C1ORF35 VPS13C JAKMIP2 SMC6 RSBN1 TRH PGM5 WDR60 CCL15 RABGGTB OVOL2 ANKRD26 NKTR PODXL2 ANKRD2 UPF3B CSPP1 CAPN3 CCDC39 KLC2 MED11 SNAPC4 AP1S2 SPSB2 GPR124 CEP164 GPRC5B CCDC12 KIAA1377 CRYBG3 ZC3H12B HAGHL LEPREL2 C1ORF173 ZNF276 LUC7L AZI1 KIAA1598 LRRC71 CGB CAPN9 DNAH2 INPP5J SEC14L3 SCGB2A1 WDR66 AMY2B ALDH3B2 BEX5 MORN1 BCO2 CCDC122 PAK3 TRIM44 SOGA3 CDK3 ADGB SCN8A C9ORF135 LRRIQ1 SPEF2 CCDC154 LRRC6 MAML3 KAZN GPATCH2 CDH23 UPF2 DNASE1L2 ABRA FAM184A FAM184A NPFF SLC6A16 IQCA1 C4ORF17 DYDC2 C8ORF47 SNX29 MORN3 ZMAT1 CCDC148 TTC18 DNAH11 EMR3 C12ORF40 C9ORF174 SYNDIG1 CHRNA10 C20ORF201 C19ORF60 KCNK12 KEL SIGLEC6 CCDC151 CLEC17A CRIPAK SSPO PLEKHG4B RGS13 C11ORF88 DYX1C1 SEPT8 ZNF683 FCRL4 MYBPH CAPN11 CFAP99 C1ORF168 CCDC37 RIMBP2 AWAT2 SH2D4B C2ORF71 CIB3 OR6V1 CD164L2 MC3R WDR64 TTC16 GAS2L2 TTC40 C1ORF228 MLL CCDC108 RGAG4 CEACAM4 RHOXF2B CACNA1F NRG2 LRRC14B C17ORF66 EBF3 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MAOA SLC36A1 DCAKD CANT1 UHRF1 IDE TM6SF2 EGR1 TMPRSS2 MALL SPINK1 ERGIC1 DNAJC11 DPY19L1 NBR1 ADAM9 ACSL3 ADA ZYG11B TCN2 COPB2 GGCX CRK TLE1 UBAP2L PLD3 CD7 SRC PRKAR2A VSIG4 UBQLN2 MXRA8 PCMTD2 CREBL2 TM7SF3 METTL7A CDK5RAP1 CEACAM6 CP SDC1 ITGA2 PPP1R14C FAM114A1 ASS1 TM4SF1 KRT17 SLC40A1 ECM1 RPS15A AQP5 RAI14 KLK11 FOPNL SCIN CYBRD1 RGL1 GPRC5A HTRA1 CEACAM5 SLC25A23 GABRP TMEM184B OGDH TOR3A GSN MYADM EFTUD2 TOP2A CCNB2 CYFIP1 FKBP9 NREP SLC16A1 ERI2 NEK2 KCNK13 SHCBP1 MYO1E PSEN2 KCTD3 FLT3 DEPDC1B IGFBP2 AURKA DLGAP5 BUB1 RRM2 CDK1 KIFC1 SAPCD2 H1F0 LAMC1 SPRY2 SMTN GLDC CALCRL BRCA2 IGLL5 PADI2 ANLN NCAPH ACO2 CDC20 KIF23 KIF20A DTL KCNMA1 RNASE3 UPK3B HEATR4 YPEL1 IGFBP3 BMP7 ZFP36L1 APLP1 COL1A1 SERHL2 MPEG1 ELANE B3GNT9 FGFBP1 LAMB3 ANXA8 ENTPD2 C1ORF106 CDH3 RHOU COL1A2 CLSTN1 WNT2B WNT5A CTNNBIP1 SHISA2 TBC1D8 RNF26 UBE2Q2 SCAMP4 RSAD2 GSG2 FANCI C17ORF53 CHAF1B CCL1 GATM PARPBP FAM83D KNTC1 GZMA ECT2 PBK RACGAP1 MELK RAD51AP1 BVES CDT1 OAS2 C3 COCH GINS1 KIF18A SEPT3 COL3A1 DHFR PREP TINAGL1 KCTD19 HPSE LIPG ANGPTL4 EPHA1 PPP2R2C PCOLCE2 TTYH3 CAV2 FOS TEK SPARC CDC42EP1 BGN KLHL5 NPNT VEGFA TMEM176B TAPBP DDX3X CHST1 PDPN IGFBP7 MARCKSL1 CYP2S1 MXRA5 NACAD MUC1 TMEM213 FEM1B EPDR1 PGAM1 GALNT7 TNFRSF21 LRP11 HSPA2 ATP2C1 SOAT1 SLCO2A1 SGMS2 ZMAT3 WDR11 E2F7 TMEM47 YTHDF1 MN1 MCU DOK4 DIAPH3 PCNXL3 LRRN4 ZCCHC12 NEDD1 FAM134C GRAMD4 MFAP4 ANXA10 FAM57A AVIL F13A1 RASD1 SLC16A12 DERL3 SLC6A4 SLC27A1 COL9A3 CYS1 CXCL11 RGN RP2 IDH2 CAB39 PAQR8 GJB2 ACOT7 KRT16 RFWD3 OSR2 ZNF426 TMEM62 C1S DYSF AZU1 PRTN3 MPO GZMB GNLY ADAM10 ADD3 EGLN3 ITLN1 FADS2 NR4A1 OLFM1 APBA1 LAMA3 ITGB6 KRT6A CDC20B NR2E1 ADAM21 CGA CXCL12 C10ORF25 MAST1 LPO GNA12 IRAK1 GLE1 SIGLEC14 NPC1 TIMP3 TXNDC5 UBAP1 API5 RAB5B PLBD2 EXOC2 COPA SEC23IP NNT TBCCD1 VSIG1 BTBD1 B3GNT2 CAPRIN1 CLPTM1 SLC46A2 SLC25A10 TMEM209 TPCN1 SUV39H1 CHST10 POLH TRMT2B PDP1 FAM118A VEZT REC8 EIF2AK1 STT3B SOCS6 SUSD2 SLC39A8 AACS CYB5RL P2RY2 IPO13 BAIAP2 SLC37A4 EPHB3 SYN1 KANK2 CTPS1 DKK3 VPS54 PLXNA2 VSIG2 EDC3 VPS37B NLRP2 SGPL1 TNFRSF11A PLIN3 CPM ECEL1 KDM6A MGAT2 TMEM144 TTPA GPC1 WDFY1 CMKLR1 FPR3 IVD ATP13A2 TRPC6 LUM SCARA3 TTI1 VCPIP1 NCAM1 ALDH1L1 ULBP2 HAVCR2 PTGIR UBR7 SMU1 CYP39A1 CYP2U1 GJB1 ACSS2 APBA2 ALDH1A2 TFDP1 GEMIN4 POC1A AKR7A2 MAP2K4 TOP3B DNTT SLC11A2 TMED3 HSD3B7 AHCYL1 EHD2 SEC24D FGD6 SFXN2 CENPT HES6 RPA1 ZP3 C15ORF62 TRIM47 ACVR1 MAP7D2 VANGL2 SULF2 KLHL13 LY6D UST FAM198B LPCAT3 CLDN12 IGFBPL1 WDR62 ANKRD13C NCK2 USP38 CDR2 PPFIBP2 DLG1 ZBTB3 PANK3 NIPAL3 FUBP3 SLC25A51 TMEM117 RBBP9 ODF2 SLC41A2 EHD3 RNF10 CIZ1 SLC12A4 DCAF12 GAN RAB3D PLK4 ANKRD29 DNAJC10 HYLS1 MATN1 REM1 GFRA3 LOXL1 FBXL7 TTYH2 BPIFB2 DES RBP1 BLOC1S3 SLC35G1 PDXP ALDH18A1 C16ORF95 SLC17A5 TCFL5 TBC1D24 FBXO28 FTO KLHL26 CASC4 PXT1 NAP1L3 SMYD1 PVRL2 GPR126 SLC44A1 SYNC UBAC2 PHTF1 SGK196 SLC22A31 GUCY1A2 SEMA5A SLC43A1 PCDHAC2 FOXN4 SH3RF3 EPHX3 SNX27 MTPAP MUC12 DLEU7 RNF39 BAIAP3 SCLY MAN2B2 MFAP2 CHRNA3 FREM1 TMTC4 ADAMTS18 PHF17 MOXD1 CNNM4 TRIM3 ZER1 ZKSCAN7 HENMT1 BHLHB9 ZBTB26 ZNF354C C17ORF51 KCNJ1 MTL5 ABHD6 EXD2 PTPLAD2 HIATL1 SLC24A6 NPIPL3 PAGE2B C10ORF76 SS18 LEPREL1 KIAA1467 UPK3BL GAST CNIH2 ZNF391 ZNF879 PATE2 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B UBL5 RPS27A RSRC2 GCC2 CNTRL WFIKKN1 CISD3 KPNB1 VPREB3 ACE2 CACNA1D FCER2 TPRN LARP7 CSNK2A2 AKAP9 EXOSC5 PPIG USP7 CHD1 NOL7 INTU GADD45GIP1 CACNB4 ELL3 PFDN5 RPS17 RPL37A TMC5 UQCR10 CGNL1 ALMS1 TPT1 RPL6 KIF21A C9ORF116 RPS15 MAPK10 BDP1 FAM183A RPL19 FMO2 RPLP1 RPS7 HBEGF DDRGK1 GPD1 ITPKB MT1F RAB13 TNFAIP8L2 LTA4H IFI27L2 MRPL51 CMTM2 NCR3 CPA3 KLRG1 IL7R KLRB1 AKT3 FCRL6 STAC TRAT1 PLCXD1 CISH HPGDS EDN1 AR CLDN3 CBLN4 FZD8 PNN TCF7L2 MAB21L1 OR2A5 TNK2 ZNF862 SETD1B GPR162 ULBP1 PPM1N CCDC88B CLEC4A LY86 GEN1 FABP4 COX7A1 RETN CCL17 CLEC6A CD19 CLEC4E CLEC4D PLEKHA4 JPH3 INHBA PTPRT APOC2 SP110 NDP CD200 SEPT4 COX17 CYYR1 DTX3L GATA2 RPS23 CHCHD2 NGFRAP1 WBP5 GPAM LUC7L3 SNRPD2 RPL22 PRDX5 ARL6IP4 C19ORF43 ATP5H RPL35 FHL1 FAM189A2 SEPW1 NDUFA2 CHORDC1 BMS1 TRMT112 NDUFC1 MPC2 C19ORF59 MYEOV2 ALOX5AP MBLAC1 TNNI2 USMG5 CDK11A YTHDC1 USHBP1 UPF3A NDUFC2 CHCHD1 C8ORF59 PIN4 NDUFA7 SCAND1 HIGD2A ANK1 ESF1 LST1 DDIT3 LTA SELM PNLDC1 TCF23 B3GNT5 C6ORF52 SOCS2 ZNF292 HMGN5 CMIP C17ORF96 IRS2 TAF1D CDC42EP3 ANP32A DPM3 MMP10 ACIN1 PFDN2 NKAP SLC29A1 LSM7 UQCRQ PTMA ATP5L HOXB7 MRPL1 BEX2 HSPE1 RPL29 AMIGO2 PLEKHH2 ARGLU1 MNS1 CREBRF ATP5E RPA3 TCTEX1D2 TMEM121 NAALAD2 ANKRD55 CELF3 GCA RIIAD1 CCDC153 CCR6 GCHFR SNX20 SSNA1 PTGDS TCAP BATF3 TPGS1 SPIB TNN LENG1 VMO1 FCAMR FNBP4 CELF6 PRPF38B GYPC CD1B MCM7 PNKP ARL13B SEC62 IFT74 TRHDE CDCA7L PILRB TOP1 PDCD7 KIF1A EIF5B CCDC173 CEP290 BOD1L1 PNISR CAPN12 RSF1 SRRM2 RBM34 ERAP2 FMR1 ENO2 SERF2 PTGS1 FOLR3 LTB LAIR2 SON MS4A1 IGIP SWT1 IL17D PPFIA4 CENPV CLK1 AIM2 TCEAL2 FCER1A LPPR4 B4GALNT1 FCRL2 HPD FFAR4 TNFRSF25 RNF113A GTF2H5 PET100 TRAPPC5 CLECL1 CARD16 IGF1 SIM2 RYR1 NDUFB1 MAPKAPK2 ZNRD1 SPDYC SNRNP27 ANKRD18A AIG1 C6ORF62 C19ORF53 LTB4R MRPL52 ANKRD11 MPHOSPH8 FFAR2 ETAA1 KCNJ2 NSRP1 RBP4 RBBP6 ALDOC FILIP1 TEX9 ATXN1 FAM173A TEP1 TMEM91 HOXB6 ITPA FAM174B PIM2 GMFG TARP RTN3 CDR1 RNMT EPC1 AMOTL1 MICAL3 SASH1 SREK1 CCDC130 PDGFA GNB3 BFSP2 OXT ACTN3 STMND1 ZBED5 LIN7B TMC1 SERPINI2 PRSS21 ZBTB4 PRSS12 JMJD1C MLLT4 CHD6 TRA2A AK9 THUMPD2 FAM9C ARHGEF38 FIS1 CPT1B FAM133B POLR2F BLK CD22 RSBN1L HYPK TNFRSF13B ENPP1 MTHFS GPR82 EXOC3L4 ABCA5 DNAH9 MCF2L2 FAM151A SCGB1D4 HOXB4 BIRC7 WDR3 TRMT6 CDK12 USE1 TCL1A DYNLRB1 RNASEH2C RTF1 TOMM7 GCSAML ARHGEF28 DNLZ MRPS21 RNPC3 UBN2 ADAM23 PHIP ZC3H6 HORMAD1 PAXBP1 C1ORF131 SVIL MAGIX NME3 BAZ2B TP53I13 SNRPF ATPIF1 SLC25A30 NAA16 GRIP2 BTNL9 ZC3H13 SEMA3D C1RL PEX16 FCRL1 RBM25 PRPF4B ZFC3H1 MAPK8IP2 EAF1 GOLGA7B C1ORF35 VPS13C SMC6 TRH FRMD4A PGM5 LSM6 AES TMEM120A WDR60 CCL15 MINOS1 ANKRD26 UPF3B CHD7 SDHAF1 CCDC39 NUDT22 SYCP2 SREK1IP1 SPSB2 GPR124 CEP164 CCDC12 KIAA1377 CCDC59 CRYBG3 LEPREL2 C1ORF173 OXER1 RPP25L UBE2QL1 LUC7L KIAA1598 CGB SAG INO80C TAF4 XRCC6BP1 SCGB2A1 CCDC125 ALDH3B2 SRCIN1 CTU1 CCDC122 PAK3 TRIM44 CDK3 ZGLP1 C9ORF135 LRRIQ1 ZNF354B CCDC154 GPATCH2 ZNF605 UPF2 DNASE1L2 POLR1D KRR1 HEXDC CHCHD5 IQCA1 C4ORF17 C12ORF65 MORN3 MTG2 ZMAT1 DNAH11 EMR3 C12ORF40 MNF1 C22ORF32 CHRNA10 C20ORF201 C19ORF60 C11ORF83 C1ORF227 CLEC17A CRIPAK SSPO PLEKHG4B RGS13 CD1E DYX1C1 PTPN20B SEPT8 CHRNE ZNF683 HTR4 MYBPH CAPN11 PRR24 CFAP99 C1ORF168 RIMBP2 AWAT2 C2ORF71 CIB3 CD164L2 HSF5 MC3R WDR64 RHOXF2B C17ORF66 C9ORF142 PSD RAB41 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 NUP210 FKBP10 TM6SF2 ABCC1 TGM4 SLC2A7 SPINK1 AADAC NPC1L1 FABP2 CLCN6 TREM2 SLC28A1 TCN2 SLC27A4 GIPC2 PDE4D TMEM176A PLD3 PTGER1 CD7 VSIG4 KALRN FRMD8 MXRA8 ERC1 METTL7A CDK5RAP1 CAV1 SDC1 ITGA2 TGFB2 NT5DC2 HIST1H2AL ASS1 OLFML2B TM4SF1 KRT17 RPS15A AQP5 UPK1B KLK11 CCDC80 FAM214A SCIN CYBRD1 SEMA3A CLCA2 GPRC5A HTRA1 CEACAM5 TMEM246 GABRP STIM1 TMEM184B NREP SLC16A1 ERI2 KCNK13 FLT3 TNFRSF17 MZB1 OPN3 TDRD9 SLC1A3 SAPCD2 HGF LAMC1 ALOX15B NRG1 PADI2 OLFML2A GLDN RNASE3 CORO6 SEMA4C PLEKHA1 UPK3B HEATR4 YPEL1 S1PR5 IGFBP3 ATR ZFP36L1 RUNX2 ABCC5 SERPINH1 COL1A1 ABCD4 MMP11 B3GNT9 COL14A1 C1ORF106 TSKU CDH3 HR COL1A2 CLSTN1 SFRP4 WNT2B WNT5A FGF9 SHISA2 TBC1D8 BMP1 UBE2Q2 DACT2 SLC24A3 CUX1 PLEKHG3 FANCI IGJ KNTC1 CD160 GZMA GP2 TRAIP NLRC3 BVES BPIFA1 PSAT1 LRP8 C3 SIGLEC1 COCH SEPT3 COL3A1 CCDC129 TINAGL1 RASA4 LIPG ANGPTL4 MAMDC2 ITGA8 LGALS12 TTYH3 TNS1 TEK SPARC KLHL5 CLDN5 VEGFA PRX TMEM176B ARRDC3 CHST1 EVA1B PDPN IGFBP7 ZNF692 MARCKSL1 MYO18A COL6A3 ACTL7B AGO4 PDZRN3 GLI3 DGKQ PLCL1 FBXO40 FUT2 WSCD1 JAKMIP3 HMCN1 COL20A1 NAPSA RADIL GPR157 PLA2R1 NAT8 AQP4 GALNT7 SMIM6 GJA1 LRP11 SOAT1 E2F7 DQX1 PPM1H ACRC MN1 COL7A1 DLG4 PRRX2 PCNXL3 LRRN4 ELMOD1 TMEM169 ARHGDIG GRAMD4 MFAP4 ANXA10 AVIL SLC16A12 DERL3 PACSIN1 GIMAP1-GIMAP5 COL9A3 SLC43A2 FAM171A1 GPR63 LAMB2 NCAPD3 NPR2 GJB2 LPCAT1 ZNF624 IGFBP1 AZU1 MPO GNLY ITGAD PDE7A ATF7IP FLRT2 HEYL PRR22 DENND3 JARID2 DNM1 SV2B APBA1 RCAN2 LAMA3 COL12A1 LPPR3 CDC20B KRT24 C6ORF10 NR2E1 ITGA9 FANCA CGA STAB1 LAMC3 SEMA3B CXCL12 SP5 CDC14A SH2D6 MAST1 CACNA1E LPO MTSS1 KRBOX1 SIGLEC14 UCHL1 BCR CDK6 GNAQ TIMP3 FBLN1 SYN3 SLC46A2 TPCN1 MPP3 CHST10 VEZT REC8 SOCS6 GREM1 CAMKK1 IGSF9B PRSS53 COL27A1 BTBD9 SMPD3 TLE4 SLC38A5 VPS13D KANK2 CHFR DKK3 PLXNA2 VSIG2 LZTR1 ARAP3 NLRP2 ELF5 SGPL1 DTX2 TNFRSF11A GCLC NPR1 CDH15 MPDZ EFEMP2 TDRD6 SLC22A3 PLXNA3 TMIE KDM4C ABCC10 PDGFB FER1L5 PITPNM2 DISC1 BCL2L11 NOTCH3 ABCA3 CYP2D6 HSF4 CMKLR1 FPR3 EEF2K PRKCG TRPC6 LUM TECPR1 FANCC USP49 ITGAE NCAM1 ALDH1L1 ULBP2 UBR3 CYP2U1 GJB1 HSD17B13 SLC23A2 ERN1 TRPM6 PODN SLC11A2 TMED3 LIPN DUOXA1 SYNJ1 KANSL3 ZNF407 FGD6 KDM5C FSTL3 NRCAM CHST7 CENPT GALNT10 HHIPL1 ZP3 C15ORF62 LOXL4 TMEM135 MAP7D2 VANGL2 PADI3 UST FAM198B SRGAP3 SBF2 ZFP90 SLC27A3 ATRN OPHN1 ALOXE3 PPFIBP2 DLG1 YIF1B PADI1 DOCK5 GPR161 PHKA1 SLC25A51 TMEM117 EMILIN1 HEATR5A DNAJC1 GAN CAGE1 ANKRD29 DNAJC10 CENPJ LAYN SEMA6C LOXL1 NGFR MAMSTR COL15A1 TTYH2 RBP1 BLOC1S3 SLC35G1 ERP27 DFNA5 NHSL1 ARHGEF40 TCFL5 TBC1D24 CPOX P2RX1 DTX1 NAP1L3 KLHL3 CCDC87 SMYD1 SOGA1 POMGNT1 GPR126 JHDM1D SOGA2 ZNF559 C9ORF163 SLC22A31 GUCY1A2 PARK2 PLXNC1 TARBP1 SEMA5A SLC43A1 HTRA3 PNMAL2 FBXO41 FOXN4 RPRML SH3RF3 LARGE DEPDC5 RNF215 MUC12 ZNF500 ZNF20 TRIM33 PKP1 ZNF700 DACT3 MAPKBP1 ZNF334 PCDHGA3 CDH24 EGFL8 KIF7 C11ORF45 BAIAP3 MFAP2 C20ORF118 CHRNA3 ADARB2 FREM1 SLC9A5 RCCD1 MOXD1 PYROXD2 TMEM74B CNNM4 GPR33 ZKSCAN7 SYT5 ZNF354C LRCH3 MEGF11 EVC2 LAMB4 MTL5 LRRC16A TMEM255A ZBTB46 PPT2 OR52B6 GRAMD3 PTPLAD2 CCKBR ZNF10 CDYL2 SLC24A6 RNF112 NPIPL3 C16ORF3 PAGE2B NKX2-8 TAS1R1 C14ORF182 LEPREL1 KIAA1467 UPK3BL MCIN BAI3 IL17REL GAST CNIH2 TMEM190 OR6B2 MYO3B ZNF391 ZNF879 TEX33 GRIN3B PATE2 ZNF384 C20ORF195 PDIA2 SYT3 CACNB1 PPP1R3G TMEM26 SLC7A4 TMOD4 IRGC C7 CNGA4 ACSM4 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 1 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 NKX3-1 GLA UBB CD79B DCTPP1 IL1B IGSF8 VCAM1 SUMO2 PRAP1 PRIM2 PFAS CISD3 NMI SLC6A20 TSPO IL1A VPREB3 DDX21 CCND3 ACE2 CACNA1D SWI5 ARRB2 CYB5B ECSIT GRPEL1 PLOD2 CLIP4 OASL EXOSC5 AGPAT2 GPHN ABHD11 GADD45GIP1 CACNB4 ASB9 ELL3 BCL2A1 PFDN5 ARL4D FRK CGNL1 ACOT13 RPL19 AIF1 FMO2 RPS7 ATP10A ACER3 ENPP4 HBEGF ALOX5 GPD1 DOK2 MARCO RHBDD2 MRC1 CD101 PNP TK1 SAP30 LPL MT1F HCCS RAB13 SHMT1 BLVRA TNFAIP8L2 CD163 SCIMP RGS16 PPARG GSTO1 LTA4H RPL26L1 SLFN11 SCD NCAPG CMTM2 IL7R CHI3L1 PDZD4 EGR3 CGREF1 STAC TRAT1 HINT1 CKS1B BMP4 ABCG1 CISH CD300C PLAUR EHHADH AR COL17A1 CBLN4 OR2A5 CEBPB COLEC12 GPR162 CD69 QPRT CFB PYCARD CLEC5A ULBP1 EMR1 FSBP CLEC4A RAC2 SLAMF9 TNIP3 LY86 VAV1 FCER1G FABP4 ADIPOQ RETN CFD CCL17 CLEC6A PSMB8 IL1RN IFIT2 CD19 CLEC4E PLAC8 CLEC4D MLKL PLEKHA4 TREM1 RNASE10 TIFA GBP2 GLIPR2 SAMD9L INHBA PTPRT UBE2L6 NINJ2 APOC2 NDP RTN2 PSME2 PFN1 TOX2 SEPT4 AKR1A1 PSMB10 DUSP1 CYYR1 TMCC3 MYL12A NFKBIA PSMB9 JUN CHCHD2 SH3BGRL COX7A2L NGFRAP1 EIF3E WBP5 SFTPC GNG10 S100A4 GPAM SNRPD2 LIMCH1 ACAT2 RPL4 PRDX5 NUPR1 ABRACL FHL1 RPS9 RGCC TRMT112 MPC2 C19ORF59 PSMA6 ALOX5AP RBM3 MBLAC1 VPS35 POLR2K TNNI2 USHBP1 BEX4 COX14 ANK1 SAMSN1 LST1 DDIT3 LTA SLA PNLDC1 EGR2 TCF23 HSPA6 ALOX12B SERPINI1 B3GNT5 C6ORF52 SOCS2 KIAA0408 PROC C17ORF96 IER5 FAM161B CDC42EP3 PDLIM1 MMP10 LAMTOR2 EMC4 ATP6V1E1 POLD2 PFDN2 SARNP SLC29A1 TAF12 COPRS TTC1 IMMP1L CCDC124 TMEM126A NHP2 FLOT2 CDC26 TPRKB LSM7 C19ORF10 PHLDA3 EMG1 PSMC1 POLR2E LYSMD2 ETHE1 HMGN4 CMC1 SNX10 BEX2 HSPE1 AMIGO2 TMEM170B HNRNPA0 MSMO1 MED10 RND1 MT1H MVD MKKS MRPL47 RPA3 TATDN2 TMEM121 ANKRD55 PCED1B S100A8 GCA MOCOS GSDMD GCHFR SNX20 PTGDS BATF3 DGAT2 TPGS1 SPIB OLR1 FPR1 TNN FCAMR NUDT1 GYPC MNDA CD1B MCM7 ALYREF DMAP1 TRHDE CDCA7L PILRB GBP1 SMIM10 CCIN CD83 ETS2 ETV7 GMPR NT5DC1 GRAMD1C ERAP2 CBR3 FCGR3B ALDH2 PTGS1 EIF1 FOLR3 CD52 RPS6 LTB PLEK LAIR2 MS4A1 HRH1 IL17D PPFIA4 CENPV CDC42EP2 AIM2 HIST2H2BF NCF1 ABCA12 HPD PDE1B FFAR4 C4A PFDN1 PSMD9 SUPT4H1 PPIE IDI1 FGR CARD16 IGF1 RYR1 HMOX2 TNFAIP8 NECAP2 TP53RK APIP FUNDC2 AIG1 KCNJ15 COPS6 CCL18 C11ORF58 LTB4R GGCT FFAR2 RBP4 RPF1 DNTTIP2 ALDOC PMF1 TMEM91 HOXB6 ITPA PIM2 GMFG EIF1B RTN3 CDR1 KCTD10 AMOTL1 RBFOX2 APEX2 BFSP2 OXT STMND1 SRA1 TMC1 SPINK7 PRSS12 TRIQK FAM9C MSRB3 FIS1 MRPS15 ENPP1 MTHFS SLC46A1 GPR82 EXOC3L4 MTHFD1L SPTLC3 MCF2L2 FAM151A SCGB1D4 DGUOK BIRC7 LSM4 HNRNPAB ENO3 NDUFS5 MGST3 PALMD DYNLRB1 ANAPC16 SSBP1 EIF3H SRFBP1 ARHGEF28 PACSIN3 DNLZ MAOB MPV17L2 S100A7 TMEM99 ADAM23 MCOLN3 RSL24D1 TMEM53 HDDC2 SVIL TMED1 MRPL55 CCDC167 ECH1 TP53I13 PHF13 SLC25A30 NOP16 SSPN BTNL9 ECHDC1 SEMA3D GCDH C1RL BPHL PNRC2 SH3BP5 EAF1 PDLIM7 ST6GALNAC4 BRSK1 LSM10 SMC6 PGM5 LSM6 SNRNP35 TMEM120A CCL15 LYAR METTL13 TNXB GAR1 CRCP NOB1 TMEM163 NUDT22 MED11 IQSEC2 AP1S2 GPR124 LRRFIP2 RCN3 MRPS17 HABP4 FAT3 SBDS GPR85 CLIC6 UTP11L RPP25L KIAA1598 SAG SEC14L3 FAM122A SS18L2 XRCC6BP1 SCGB2A1 ARL16 ALDH3B2 SOGA3 PUS3 S100A7A CXCR7 CCDC154 SLC6A16 C4ORF17 FER1L6 H3F3C C12ORF40 C11ORF75 C20ORF201 RTN1 SEPT11 CCDC149 SSPO RGS13 C11ORF88 CD1E SEPT8 CHRNE ZNF683 CAPN11 AWAT2 SH2D4B HSF5 MC3R WDR64 IGSF21 PROSC C2ORF70 PSG3 TATDN1 LHX8 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FOXRED2 DCAKD EMC1 CANT1 ERMP1 FAM8A1 SLC5A2 SYVN1 IDE ANPEP ERGIC1 SUN2 PPP2R1A MOGS HEATR3 TMBIM1 PFKL PVR COL4A1 ADAM9 KCNQ1 ACSL3 GPAA1 PIGO PITRM1 ZYG11B SERPINE1 GGCX MID2 COL4A2 NUCB1 VARS TLE1 UBAP2L RETSAT CLCA1 WFS1 VPS11 STOM VSIG4 APP UBQLN2 SCARB1 FRMD8 FCGBP TMEM236 MAPK1 SIPA1L1 PCMTD2 HSD3B2 TM7SF3 EI24 METTL7A ALDH6A1 FZD5 ACO1 CDK5RAP1 FECH TMEM86A NAGLU AK4 PIGR ASS1 SLC40A1 RPS15A AQP5 HIST1H1E PTGFR SCIN CLCA2 HTRA1 CEACAM5 SLC25A23 GABRP TMEM184B SYMPK OGDH PNPLA2 SEL1L SLCO2B1 SIK2 GSK3A TOR1B ACSS1 H6PD GAA SUMF2 ZDHHC7 MYADM PLOD1 KCNAB2 GANAB HK1 ABCC3 SLC1A5 ACLY NCSTN DHCR24 ZNF100 CYFIP1 FKBP9 SLC16A1 MARVELD1 LDLR CLCN4 ADPRH FKBP5 PDGFC SLC1A3 C2 PADI2 ACO2 SORT1 SCD FGFRL1 AKAP12 TGFBR3 SERHL2 MPEG1 CYP4V2 TRAPPC9 ASB7 SPINT1 MLPH FAM84B TSKU IRF6 TPD52L1 SPDEF MCCC2 LMX1A SHISA2 ELP3 RNF26 STK40 SCAMP4 DHX34 DGCR2 SLC12A7 RSAD2 OAS3 FANCI GP2 IFIT1 BVES SLC7A8 OAS2 C3 COCH GINS1 CA7 PREP BMPR2 EPAS1 TGM2 MED18 SFTPA1 ADAMTS15 CCKAR HIPK3 TEX261 CYP2B6 GNS FAM102B SLC25A25 AOC3 NOS2 NCKIPSD CPT1C COL20A1 MRI1 RADIL FOXK1 MUC1 ADRA2A C1ORF233 FEM1B GTF2E1 RRM1 GYS1 SEC61A1 BFAR DPP3 GNG12 SGMS1 SEC24B CHTF8 HSPA2 PRPF8 SLC25A46 TTC7B SLCO2A1 NCOA4 ZMAT3 WDR11 PPM1H KRBA2 C19ORF54 PGM1 IP6K3 CDH6 ZNF671 PIGW PNPLA3 MOCOS ANKFY1 SLC16A12 KLHL6 SLC27A1 BTBD2 FAM171A1 PLAGL1 VPS41 CAB39 SLC47A1 PPP1R3D CRKL PAQR8 XPOT DBR1 RFWD3 ZNF426 FAM210B COPG1 SEC31A NCEH1 CHP1 EIF4G2 ST6GAL1 ZNF546 FLRT2 LONRF1 TRIM16L ITLN1 OLFM1 APBA1 NPTX2 SF3B3 GNA12 IRAK1 NPC1 STARD7 TXNDC5 ARCN1 GRSF1 RAB5B PLBD2 EXOC2 COPA LARS2 SLC30A5 SLC35A4 SEC23IP WDPCP NNT MCFD2 PNPO CITED2 CLTC BTBD1 CLPTM1 SLC46A2 SLC25A10 XPNPEP3 CHST4 POLH TRMT2B MTA2 RIN2 HIRA C16ORF62 AGPAT3 CLDN1 EIF2AK1 STT3B CAMKK1 AACS PEX10 HECTD3 BAIAP2 POLR2A MFSD12 TMEM129 STK24 TRPC4AP PXDN TTC7A KCTD10 VPS54 SLC9A1 RAF1 VSIG2 SLC25A44 EDC3 RPS6KA4 TNFRSF11A RAB6A GHR SREBF2 CHDH MUC2 NUP160 ELAC2 RDH11 TMEM168 HLCS IL6ST MAP3K5 GSR SLCO1A2 PIK3R4 OR1K1 WDFY1 ATP13A2 SPHK2 UBIAD1 RABGAP1 PGAM5 PLD1 FANCC TTI1 ZNF627 SNX13 SLC46A1 ABCA2 LMF1 TRIM35 SMU1 CYP2U1 SLC5A6 GJB1 HSD17B13 SLC15A4 NCOA1 ACSS2 CRAT CREB3L1 NUP205 GEMIN4 AKR7A2 TOP3B SLC11A2 CRTAP AHCYL1 TUBGCP4 SLC39A6 TMEM248 SPATA2 SNX19 SEC24D EPS15L1 ELMSAN1 ARHGEF28 IL17RB SFXN2 DHCR7 RERG TMEM135 TFCP2L1 PADI3 MAN1C1 DENND4C FAM198B LPCAT3 CLDN12 GPD1L HGSNAT LGR4 PDPR USP38 INTS7 A4GALT KIAA1191 MED16 PPFIBP2 LMF2 FBXO38 SMYD5 ZBTB3 TBC1D16 ATL3 ARL10 SNTB1 SLC25A51 RBBP9 ERLIN2 TM9SF4 ZDHHC9 GPBP1L1 RNF10 HSPA12A SND1 HEATR5A CIZ1 SLC12A4 MSTO1 DCAF12 MFAP3L GAN KLHL8 GFRA3 MGAT3 FBXW8 TMEM63A SLC35G1 PDXP ALDH18A1 ERP27 KIAA0196 PDP2 LDLRAD3 SLC17A5 CHAMP1 TBC1D24 ALDH5A1 CDIP1 ADCK1 POLR1B IPO11 EXT2 TOP3A SLC39A9 SMYD1 SOGA1 SLC44A1 LRP12 SOGA2 GPR124 FTSJD1 TMEM184C LMBR1 MTMR4 GHDC PARK2 RCBTB1 KCNA3 CWF19L1 EVI5L DUSP3 SNX27 MTPAP SLC5A7 FAM189B ELMO2 LARGE DCTN5 BET1L DCAF6 CBLN3 RNF141 DCAF16 GYG2 ZNF846 MAN2B2 IL20RA TMTC4 ADAMTS18 PHF17 ANKRD36 EVC PTPN9 ST6GALNAC3 ST6GALNAC3 OSBPL2 EARS2 ZER1 GTF3C2 GCN1L1 GUCY1B3 ZNF354C EVC2 ANGEL1 FER1L6 SLC4A11 C16ORF89 CDC23 COG1 EXD2 LDOC1L ZNF429 C9ORF106 KIAA1737 HIATL1 GPR77 CA5B CDYL2 ZNF417 GENE-N C10ORF76 C16ORF96 SS18 UPK3BL SH2D4B ZNF879 CNGA4 PSG3 CT62 ZDHHC3 TENC1 PRR4 CAPN13 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B UBL5 BIRC3 GCC2 CCL5 COL6A1 WFIKKN1 VCAM1 CD200R1L KPNB1 VPREB3 JAKMIP1 CEP135 TPRN CD200R1 RYBP LARP7 TREM2 ITM2A PPIG CD244 CDK2 NOL7 ASB9 ELL3 XPA UQCR10 ARL3 GATAD2B SPAG16 ZEB1 CKS2 OTUD7B FMN1 MAPK10 BDP1 FAM183A C2ORF73 TMIGD3 DCDC1 LSP1 C1QC C1QA TBC1D10C TMED9 CLSPN HMMR MT1F MZB1 RNASE1 BIRC5 FCRL5 RGS16 SLFN11 IFI27L2 BCL11B LRRC43 CD247 ARL4C IL7R CST7 MATK ZFYVE28 NTRK1 SPON1 EGR3 PRSS57 FCRL6 TRAT1 GADD45B BATF FGFR1 HPGDS EDN1 MEF2C NKD1 PNN ERVW-1 MAB21L1 TNK2 FBRS SETD1B SMC2 LAT CD6 GPR65 CD69 SIT1 GNG2 RGS1 PSTPIP1 CREG2 CD3G SKAP1 SEPT1 CAMK4 SLAMF7 GIMAP7 LCP2 SH2D1A TNFRSF9 CTSW CD27 HELLS HCST LCK CD3D PTPRCAP CORO1A CENPM TNFRSF18 CD96 HMGB2 FYB CD2 LY9 TBX21 GZMK LAG3 DNASE1L3 PON1 BEX1 PGAM2 CLEC6A FOLR2 EVI2A CD19 MMP12 NAV3 RAMP1 VCAN CLDN2 RASA4 SAMD9L INHBA ETS1 TOX2 CD200 PLTP CHMP4B TXN ID3 SYF2 GATA2 U2AF2 PSMB9 GDPD3 CHCHD2 LUC7L3 C19ORF43 GIMAP8 SHFM1 FAM189A2 LIMD2 RTKN2 NDUFA6 MBLAC1 CETN3 USMG5 CDK11A YTHDC1 ATP2B1 CHCHD1 C8ORF59 PIN4 SCAND1 CELF4 RRAD CLEC2B DDIT3 LTA PI16 PNLDC1 SERPINI1 ADORA1 CCND2 C6ORF52 MRC2 EDNRA TENM2 NTNG2 SAMD15 TMEM52 ZNF292 C1ORF204 HMGN5 CMIP C17ORF96 ANP32A DPM3 SNRPG HMGB3 EMC4 ACIN1 C7ORF55 PTTG1 UQCRQ SSB HOXB7 ERH CBX1 HSPE1 ARGLU1 TTC32 WFDC3 HNRNPA0 MNS1 C15ORF65 PURB TIFAB C17ORF50 MMP9 ATP5E TCTEX1D2 PSD3 SLIRP P2RY14 SUSD3 LAT2 FAM105A S100A8 AMICA1 RIIAD1 CCDC153 POU2AF1 CCR6 GCHFR GPR183 SSNA1 TRAF3IP3 TCAP TSPAN33 GPR18 SPIB RGS10 TMEM40 TESC PVRIG FNBP4 CNGA3 CD1B PGBD3 ALYREF SEC62 IFT74 ZRANB2 USP44 CCDC173 XRCC4 CEP290 PNISR FMNL2 RSF1 DUSP4 ERAP2 FAM65B ENO2 U2AF1 SERF2 TCEB2 SRSF11 CDKN1B LTB LAIR2 MS4A1 KLRF1 LPAR6 CCDC178 P2RY10 SWT1 PTPRE CLK1 DAPK2 ENTPD1 OLFML3 CD70 ADAM19 FAM101B TCEAL2 FCER1A B4GALNT1 FCRL2 SCUBE3 SLC6A13 GFI1B CD40LG TNFRSF25 GTF2H5 PET100 CLECL1 FUT7 C19ORF38 CARD16 PAX5 NDUFB1 FKBP2 ZNRD1 COX20 COX19 ANKRD18A KCNJ2 RBBP6 USP16 TEX9 MRPL33 CWC15 IFT81 ATXN1 TRAPPC6A MSI2 PIM2 GAPT TARP RNMT EPC1 SNAI1 SREK1 HEXIM1 TMPRSS6 USF2 BFSP2 OXT ACTN3 SPINK7 SYCE3 MLLT4 CHD6 CTTNBP2 SMC4 PDGFB AK9 ARHGEF38 STX17 CPT1B FAM133B BLK IGFLR1 SCN9A CD79A SESN3 RSBN1L HYPK SNAI3 TNFRSF13B FLT3LG S1PR4 CLEC2D LTBP1 DNAH9 ABCA13 DRD2 TTC36 ABCA6 MAT1A BIRC7 CDK12 TCL1A RCSD1 PLCG1 JOSD2 DYNLRB1 SLC4A7 TOMM7 TNIK DNLZ MRPS21 LRMP RNPC3 UBN2 CMYA5 FAM171B FAM228B MYRF C11ORF95 PAXBP1 CCDC167 PHF21A SETD1A ATPIF1 LSM5 ARID4B GRIP2 CCDC171 RASAL1 LRRCC1 SPA17 PRPF4B MAPK8IP2 SFMBT2 TVP23A CLEC10A C1ORF35 TYW3 ADAMTS7 CENPB AES DNAH12 WDR60 MINOS1 ANKRD26 FAM213B UPF3B DTX1 INA MAP9 CCDC39 SPSB2 DDX11 LSMD1 CEP164 KIAA1377 NPHP1 KIAA1009 C1ORF173 CCR10 FAM154B LUC7L SAG PPP1R35 WDR66 ALDH3B2 OFD1 SRCIN1 LRRD1 SCML4 MORN1 CCDC122 PAK3 SMIM4 PHF14 CCDC181 ZGLP1 CALML4 C9ORF135 LRRIQ1 CIR1 PFN4 LRRC6 GPATCH2 CDH23 UPF2 RGS9 DNASE1L2 ABRA ZC3H8 GFRA2 KRR1 CHCHD5 IQCA1 PLAC4 MST4 C2ORF54 MORN3 HMGXB4 ZMAT1 CCDC148 GPR97 C12ORF40 PNOC MNF1 ICAM4 CHRNA10 C20ORF201 SIRPG CXORF65 CLEC17A DOCK3 SSPO EFHA2 RGS13 C11ORF88 CD1E DYX1C1 C1ORF100 PRSS41 FCRL4 CCDC11 MYBPH CFAP99 C1ORF168 SCG3 CD164L2 DPRX NTN5 KIAA1407 TTC40 ACYP1 RGAG4 CEACAM4 CEP89 PPP1R42 ARRDC5 C19ORF18 MAMU-DQB1 C1ORF141 UNC13A REM2 C17ORF85 PTTG2 CDKL4 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 SYVN1 IFNA1 CD34 VDR SUN2 DDX58 CXCL10 PLA2G2D CUL1 NDRG1 LAP3 JAK2 ADA MPZL1 NFKB1 HMOX1 SERPINE1 OAS1 MYO7B FN1 STAT1 TRIM25 EPB41L3 EIF2AK2 PLD3 CLCA1 APOBEC3G OASL CRTC3 MOV10 IFNB1 ISG15 SRC TMED5 LILRB1 CXCL9 LNPEP FRMD8 EDEM1 IL10 MX1 MYD88 TMEM86A PLEKHO1 SERPING1 CEACAM6 TNFSF10 ASS1 IFI27 KRT17 ZC3H12D CD180 CCDC80 APOBEC3A RGL1 CD300E HTRA1 CCL8 ISG20 PLA2G7 CEP170 TMEM184B UNC93B1 PARP10 LGALS3BP TOR1B SHC1 ARHGEF10L H6PD MYADM TYMP BST2 APOL2 ITGA5 SLC38A7 FLVCR2 ZNF100 ARHGAP31 VSIG10L SCARB2 NREP TMEM106A FRRS1 IFI44 FLT3 ADAP2 LHFPL2 FKBP5 STARD13 MCM2 BUB1 IRF5 SLC1A3 MAFB SCIMP EPSTI1 BATF2 GNPDA1 RUNX3 SLC2A6 SLC2A5 ZFP36L2 MPEG1 APPBP2 RHOU CXCL13 LAMP1 ELF4 TBC1D8 UBE2Q2 STK40 FCN1 HELZ2 SLFN13 RSAD2 OAS3 SLC37A2 IL10RA IRF7 ZBP1 NLRC5 PLA1A TAP1 LILRB4 MS4A6A PIK3R5 GZMA IFIT1 FAM26F CCR5 IFIT3 RTP4 IFIT1B TLR7 OAS2 CD86 C3 PHF11 SIGLEC1 XAF1 CH25H APOL6 CCR1 CXORF21 DHX58 IL1RN USP18 CMPK2 IFIT2 IFI16 HERC6 IFIH1 MLKL STAT2 PML PLEKHA4 ADAR NAMPT GBP2 PARP9 PARP12 SAMD9L GCH1 HSH2D IFNA4 GBP6 HPSE LIPG PARP14 SOCS1 TRIM6 TRAFD1 SAMHD1 PPA1 PARP11 GFPT2 UBE2L6 AIDA TLR3 WARS GAL3ST4 PCOLCE2 TTYH3 EHD4 BMPR2 THBD LY6E IGFBP4 RASGRP3 DTX3L DRAM1 CTSH IFI44L PRX SERPINB9 GIMAP8 HIPK3 DDX3X ITPRIPL2 GIMAP4 TEX261 IGFBP7 GNS THEMIS2 NRP1 MARCKSL1 FSCN1 IFNA10 SLC25A25 PLCL1 IFNL1 IL27 TRIM22 C21ORF91 PLA2G4C CLN8 GIMAP2 ADRA2A ZNFX1 SH2B3 MAGT1 SEC61A1 TNFRSF21 PRPF3 PNPT1 GNA13 APOBEC3C SAMD4A RIPK3 FAM129A BTBD11 GNB4 NEDD1 GRAMD4 TAP2 PRF1 ADRB3 SLFN5 IL15RA MB21D1 TRIM21 MOCOS USP25 FAM46A ZC3HAV1 SPPL2A TRIM5 TDRD7 TRIM14 PCGF5 ANKFY1 NCKAP1L PIK3CG GIMAP1-GIMAP5 STAP1 CD38 RAB44 CXCL11 SLC43A2 IFI6 DRD1 PLAGL1 DDX60 C9ORF91 TFPI2 STARD4 C19ORF66 TNFSF13B XRN1 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 SAMD9 GBP1 SLC47A1 CKAP4 PSTPIP2 PAQR8 GJB2 KLHDC7B CDK17 RELB ETV7 NFE2L3 TICAM1 NAPA SP140L RHBDF2 SMCHD1 TMEM62 C1S PANX1 RABGAP1L IFNA2 BLZF1 IFNA14 PIK3AP1 GTPBP2 TRIM26 RAB8B DYSF AZU1 PRTN3 CSF2RB CCR7 XPO1 GZMB ADAM10 ARHGEF3 P2RY6 PDE7A GRAMD1B ITLN1 IFNA6 SDC3 ENPP2 C6ORF10 CD80 NCOA7 PPM1J CXCL12 RHBDL3 PDE1B MAST1 IFNA8 IFNA17 IRAK1 RAB35 IFNA21 SIGLEC5 NADK SIGLEC14 AQP9 CAMK2D NPC1 MRAS TNFRSF1B HARS GBA PLBD2 BAK1 PI4K2B SEC23IP MCFD2 CITED2 B3GNT2 SLC46A2 ST3GAL5 MTA2 RIN2 HIRA ERAP1 STT3B TMEM123 SLC39A8 FBXO10 ATP13A1 MFSD12 TLE4 TFEC LILRA1 JAK3 C9ORF66 TRPC4AP ELK3 SLC38A5 SGPL1 RPS6KA4 GLS TNFRSF11A NLRP3 PLIN3 CDH15 DNPEP ABI3 SRGAP2 KAT2A CMKLR1 FPR3 LILRA2 ATP13A2 SPHK2 UBIAD1 KCNA5 SMCR8 VCPIP1 LPCAT2 TREML2 HRH2 HAVCR2 PTGIR IL17RC PSMF1 SMU1 NR1H3 SLC15A4 SLC23A2 LIMK1 WSB1 ALDH1A2 KCNIP3 NUP205 MCMBP ST8SIA4 CASP10 UBP1 DOCK8 MMP17 DSE TMEM51 MFSD1 ARMC8 QKI SNX19 ARHGAP17 SEC24D AEN TTPAL HHIPL1 GNA15 LIG3 FAM49A SULF2 NHLRC3 SLC9A7 CNP PHLPP2 PPFIBP2 SLC35F6 ATL3 SNTB1 NT5C3 GIMAP6 DR1 SCN1B NGFR DES LDLRAD3 SCAPER AATK POLR1B MPP1 ERO1L MED17 FAM53C ASPHD2 C1GALT1 RAP2A SOGA1 KIRREL2 TMEM184C RNF144B MTMR4 HTR7 CWF19L1 SNX27 MTPAP TBC1D1 DLEU7 KIAA1199 FTSJD2 CHRNA1 ARHGAP22 EVC2 HSDL1 POLK KDM2B TMEM255A ABHD6 PARP15 APOBEC3H GGT5 OR52B6 KIAA0226 CDYL2 TIGIT CLNK MARCH1 SLC24A6 STARD8 GENE-ORF10 GENE-S GENE-N GENE-ORF1AB C10ORF76 GENE-M SS18 LRRC33 PRDM14 PSG3 PRR4 GENE-ORF7AB GENE-E GENE-ORF8 GENE-ORF3A GENE-5PUTR Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 FAM3B GCC2 CNTRL SH3BGR WFIKKN1 MAP1LC3A ACE2 TPRN TST ITM2A AKAP9 FBP1 ABHD14A PKIG H2AFJ ARHGEF12 VAMP8 SAT2 KLF12 CISD1 PTTG1IP NDUFB6 ASB9 XPA PFDN5 NBEA ENKUR TMC5 TFF3 TSHZ2 FAM229B C20ORF85 UQCR10 CCDC30 TSGA10 ARL3 BMPR1B DEPTOR NEK10 KIF21A C9ORF116 NME5 MAP3K19 PBX1 NFIB SPAG16 SOX2 SCEL KLHDC9 PLCB4 BCAS1 EPCAM TSTD1 C9ORF24 OTUD7B CRCT1 DYNLRB2 FMN1 MAPK10 NDRG2 FAM183A MORN5 C2ORF73 PIP PTPRZ1 ANK3 CHST9 FMO2 WDR78 AKAP14 PLEKHS1 HBEGF RNASE2 UACA CES1 ADAMTS2 SLFN11 IFI27L2 ANG LRRC43 CPA3 NCALD FCRL6 BAD AVP SDR16C5 HINT2 BMP4 CDH1 HPGDS SNPH CLDN3 NR2F2 NUCB2 SORCS1 MAB21L1 CYHR1 QPRT CENPM PON1 FABP4 RYR2 MB EFCAB11 CLEC4E RAMP1 RHCG BTBD16 INHBA PTPRT HSBP1L1 EPHB6 DBP CNGA1 CYP4B1 COX6A2 PLTP CYYR1 TPPP3 GSTP1 GDPD3 CA2 FBXO16 CYB5A CRIP1 LUC7L3 ARL6IP4 TMEM160 GSTA3 CETN2 C6ORF57 FAM189A2 SOD1 MXD4 MYLK NDUFA6 CETN3 MYLPF UPF3A NDUFC2 PIN4 NDUFA7 SCAND1 TMEM256 HIGD2A S100A13 RSPH10B CELF4 CAPSL LCA5L SELM ZSCAN1 IL13RA2 ABCA4 C6ORF52 RSPH4A EDNRA SAMD15 TMEM52 HMGN5 PABPC3 PROC DPY30 ANP32A DPM3 PDLIM1 EMC4 MSRB2 C7ORF55 MRPS33 RNASEH2A NKAP C12ORF57 IMMP1L WDR54 SCG5 SPSB3 MORC4 GP1BB CNFN CLHC1 WFDC3 MNS1 C15ORF65 PIR MEIG1 TCTEX1D2 RIIAD1 CCDC153 FAM161A CLDN8 GCHFR SPNS3 WDR86 TPGS1 C2ORF40 TMEM40 RASL11A BFSP1 CDKN2C VMO1 RP1 FCAMR SLC51A CLGN AGR3 CD1B PSIP1 CCDC68 ARL13B CEACAM7 SEC62 IFT74 TMEM107 LIPH MEIS2 PPP1R9A CCDC173 CEP290 PNISR CCDC160 CAPN12 CTNNAL1 SERF2 PTGS1 TCEB2 CCDC178 GRAMD2 DISP1 PIK3R3 CACNA2D3 ERBB4 TMEM255B TCEAL2 FCER1A PIWIL2 RSPH1 SCUBE3 CCDC34 PRDX2 BDKRB2 GTF2H5 ZDHHC11 MLLT3 CTSF GSTK1 ABCB11 AIG1 CMTM7 CSRP2 MPST ISL1 DYNC2H1 FILIP1 HSPB11 TEX9 MRPL33 HLTF IFT81 LRRC49 MEGF6 TMEM91 MATN2 HOXB6 TRAPPC6A KCTD15 METRN MSI2 YPEL3 DNAH7 TSPYL2 CST6 OXT ACTN3 PIH1D3 STMND1 BMX SLC9A4 DUOX1 CABYR LIN7B MAGI1 ZBBX PRSS21 MLLT4 ARHGEF37 CHD6 FXYD3 UNC5C FANK1 AK9 FIS1 BIK SESN3 ZNF749 DNAH5 ABCA5 LTBP1 DNAH9 ABCA10 TTC36 SCGB1D4 MGMT PIH1D2 COL16A1 ANTXR1 ACSF2 TOMM7 MOK PXMP2 DPCD DNLZ RIBC2 MRPS21 TLL2 DZIP3 LCA5 TMEM99 RNPC3 UBN2 FAM228B CCBE1 MACROD1 ECI1 MAGIX NSMCE1 NME3 NEK1 ATPIF1 GRIP2 CCDC171 SPA17 SEMA3D ARHGEF9 ACADL ECI2 RASSF9 C1ORF35 SPAG17 CCDC146 IL17RE AES DNAH12 WDR60 FAM177A1 CCL15 MINOS1 OVOL2 ANKRD26 ANKRD37 C17ORF89 MIR205HG HSD11B1L CMC4 UPF3B FAM134B CSPP1 COA5 PDE6B GNG7 MAP9 CCDC39 C16ORF55 TCEAL4 SPSB2 POLR2I LSMD1 KIAA1377 NPHP1 EFCAB2 CDKL2 HAGHL C1ORF173 CLIC6 FAM154B ODF2L PCDP1 RAB17 LUC7L AZI1 LRRC71 CGB CAPN9 SEC14L3 IFT27 SCGB2A1 WDR66 AMY2B FBXW10 ALDH3B2 CXXC4 HSD17B8 TCEA2 OFD1 BEX5 MRPL36 MORN1 BCO2 CCDC122 FBXO15 ZNF229 FAM200B CCDC181 AK7 ZGLP1 CALML4 LEKR1 C9ORF135 LRRIQ1 KLHL32 SPEF2 C7ORF41 C14ORF37 PACRG LRRC6 KAZN MYADML2 ELMOD3 TCTEX1D4 DNAH10 FAM184A FAM184A ALS2CR12 SLC6A16 CHCHD5 IQCA1 DYDC2 C8ORF47 PAPPA2 GMNC ZC2HC1A MORN3 C7ORF63 ZMAT1 CCDC148 CCDC33 C5ORF49 WDR16 WDR96 DNAH11 WDR93 PLAG1 FAM81B FAM92A1 PGBD1 EMR3 MS4A8B C12ORF40 MNF1 C9ORF174 AHI1 C20ORF201 COPZ2 ZNF688 CCKBR C2ORF62 ANKRD35 SSPO RGS13 C11ORF88 CD1E DYX1C1 SPINK8 C1ORF100 PRSS41 CCDC11 DYDC1 C1ORF168 CCDC37 SCG3 CCDC19 CIB3 DNAH6 CD164L2 CCDC67 DPRX LRRC36 KIAA1407 MORN2 EFHB TTC40 SPATS1 C1ORF228 WDR52 ACYP1 DNAJB13 CALY TMEM190 CEP89 PPP1R42 C1ORF141 SPATA17 C10ORF67 C1ORF146 C3ORF70 C1ORF101 CXORF58 AGBL4 SERP2 FAM194A Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 SPTB UHRF1 TMEM37 CD34 VDR DDX58 PTCRA CXCL10 HEATR3 PLA2G2D IFITM1 COL4A1 NDRG1 JAK2 ADA TREM2 OAS1 TUBA1C COL4A2 FN1 UBQLNL STAT1 TRIM25 SFN EIF2AK2 IL22RA1 PLD3 CLCA1 OASL CRTC3 MOV10 ISG15 SRC VSIG4 CXCL9 FRMD8 MX1 MXRA8 METTL7A CDK5RAP1 TMEM86A PLEKHO1 SERPING1 BPIFB1 KRT5 NT5DC2 ASS1 OLFML2B TM4SF1 IFI27 KRT17 ZC3H12D RPS15A AQP5 FOPNL HIST1H1E CCNO TNS4 CD180 APOBEC3A HIST1H2BK ZEB1 CLCA2 RGL1 CD300E GPRC5A HTRA1 CCL8 ISG20 PLA2G7 HIST1H1D CEP170 GABRP TMEM184B PARP10 LGALS3BP TOR1B APOL1 MYADM TYMP BST2 APOL2 ITGA5 TOP2A ZNF100 VSIG10L CCNB2 NREP TMEM106A IFI44 FLT3 LHFPL2 FKBP5 STARD13 TNFRSF17 MZB1 OPN3 SERPINB10 MS4A4A AURKA DLGAP5 BUB1 RRM2 SLC1A3 MAFB KIFC1 SCIMP EPSTI1 HGF EPHB2 BRCA2 IGLL5 CDC20 PKMYT1 ANKLE1 MKI67 DTL CCR9 RUNX3 PTPRS EPHB1 RUNX2 SLC2A5 SLC24A4 MMP11 TGFBR1 HMGA1 KRT14 MEF2C CXCL13 TCF7 IRF4 TBC1D8 MAP2K6 SLC24A3 FCN1 HELZ2 KLRD1 RSAD2 OAS3 CLEC4C KLRC1 IRF7 NKG7 FANCI ZBP1 CCL1 CD28 FAM83D PLD4 MS4A6A CD27 IGJ KNTC1 PIK3R5 GZMA TACC3 PBK IFIT1 FAM26F RACGAP1 GPR31 CCR5 GPR171 BVES IFIT3 IFIT1B CDT1 TLR7 SLC7A8 OAS2 CD86 C3 PHF11 SIGLEC1 XAF1 APOL6 CXORF21 DHX58 USP18 CMPK2 IFIT2 IFI16 SEPT3 COL3A1 DHFR HERC6 IFIH1 STAT2 PML ADAR RASA4 PARP9 SAMD9L HSH2D LIPG SLC39A14 PARP14 TRIM6 SAMHD1 PARP11 UBE2L6 GAL3ST4 SLC35F3 TTYH3 THBD LY6E IGFBP4 RASGRP3 DTX3L CDC42EP1 CTSH IFI44L GIMAP8 NSMF C10ORF10 GIMAP4 LIMD2 PDPN IGFBP7 TCF4 THEMIS2 NRP1 MARCKSL1 POU2F2 PLCL1 CYTIP AURKC TLR6 TLR9 NAPSA FAM129C PLA2G4C FOXK1 CLN8 GPR157 ADRA2A GALNT7 ADSL HSPA2 ODC1 KHDRBS3 TMEM194A SRPK3 MN1 SAMD4A GZMM LRRN4 GNB4 PCSK1N MAP3K14 GRAMD4 PRF1 ADRB3 PNPLA3 SLFN5 MB21D1 SELL TRIM5 ANKFY1 SLC16A12 FCRLA BTLA BCL11A DERL3 SLAMF6 PACSIN1 GIMAP1-GIMAP5 FAIM3 CD38 CXCL11 SLC43A2 PVRIG IFI6 PAQR6 FAM171A1 SLC20A1 DDX60 IDH2 C9ORF91 APOBEC3B TNFSF13B MX2 IFIT5 HERC5 SAMD9 SLC47A1 LPCAT1 KLHDC7B RELB CHST15 SMCHD1 BTN3A1 C1S BLNK IL18R1 RAB8B DYSF AZU1 PRTN3 SNN GZMB GNLY CUX2 P2RY10 PDE7A FLRT2 CYP26A1 GRAMD1B BACH2 FADS2 OLFM1 SDC3 ENPP2 KRT6C ADAM19 KRT6A CDC20B RDH12 CARD11 P2RY8 C6ORF10 PPM1J SLCO5A1 NPTX2 SH2D6 MAST1 IL21R IRAK1 SIGLEC5 SIGLEC14 AQP9 NPC1 HIST1H1B PAX5 PLBD2 SP140 PI4K2B VTN SEC23IP MCFD2 SLC46A2 KIRREL ST3GAL5 HIRA TMEM123 TIGD7 TRIP6 HAPLN3 GAL MFSD12 TLE4 TFEC JAK3 C9ORF66 SLC38A5 CTPS1 PELO RPS6KA4 TNFRSF11A PLIN3 NPR1 CDH15 DNPEP MUC2 ABI3 PTP4A3 FER1L5 SRGAP2 GPC1 SLC9A9 KAT2A BLK CMKLR1 FPR3 CD79A KCNA5 ULBP2 TREML2 HAVCR2 PTGIR SLC15A4 ERN1 MAPK12 ALDH1A2 KCNIP3 TTC9C NUP205 PKN3 ST8SIA4 RCSD1 SH2D3C MMP17 SEL1L3 ARHGAP17 SEC24D FGD6 AEN CHST7 CENPT HES6 SYNGR1 HHIPL1 ZP3 GNA15 VANGL2 SULF2 RAB15 PADI3 LY6D CCDC50 GFRA1 TMEM156 CNP GPRIN2 PHACTR2 SNTA1 PPFIBP2 YIF1B CREB3L2 LPAR5 FBXL18 ARL10 SLC25A51 GIMAP6 GRAP FCHSD2 CEP85L SFMBT2 GAN MAN1A1 PLK4 NGFR COL15A1 ERP27 PALD1 ARHGEF40 SUSD1 PROSER1 SEPT6 ADCK1 MPP1 TOP3A ASPHD2 KIRREL2 SOGA2 TMEM184C MTMR4 TCP11L1 SEMA5A SLC43A1 FBXO41 MTPAP GPR114 TTC24 PLEKHD1 MUC12 PKP1 CNR2 C11ORF45 DLEU7 RNF39 ZNF101 ENHO C20ORF118 CHRNA1 ANKRD36 MOXD1 CBFA2T3 ST6GALNAC5 PIP5KL1 ARHGAP22 SLA2 MTL5 KIAA0226L POLK KDM2B TMEM255A PARP15 APOBEC3H GGT5 KLRC3 AIRE ZBTB46 PYHIN1 OR52B6 SIAH3 CDYL2 TIGIT CLNK MARCH1 SLC24A6 NPIPL3 GENE-N LEPREL1 KIAA1467 KLRF2 PSG3 NEURL Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 NINL BAIAP2L1 ACE2 MIPOL1 TPRN SIGLEC15 IQUB USP2 TST AGT CLIP4 FBP1 GPHN PKIG ADHFE1 UNC119B ASB9 TPSAB1 NBEA ENKUR TMC5 TFF3 FAM229B KCTD1 CCDC30 FRK TSGA10 DNALI1 CEBPD IL5RA ARL3 BMPR1B MUC15 NEK10 C9ORF116 NME5 MAP3K19 TOX3 FOXP2 NFIB SPAG16 TMEM232 KLHDC9 BCAS1 MAP6 USP51 WDR63 C9ORF24 CRCT1 DYNLRB2 MAPK10 FAM183A MORN5 C2ORF73 DCDC1 MAP7 FMO2 WDR78 AKAP14 ENPP4 HBEGF ALOX5 RNASE2 UACA CES1 SLFN11 LRRC43 CPA3 CRIP2 PTCH1 MLF1 PDZD4 NCALD DZANK1 BAD AVP BMP4 CDH1 LRP2BP AR CLDN3 WLS FGF12 CBLN4 WNT5B SORCS1 CCDC170 CMTM8 ST6GALNAC2 QPRT CLEC5A TMEM45B CCL24 MB EFCAB11 CLEC4E MMP12 CLEC4D RAMP1 BTBD16 INHBA PTPRT EPHX1 CYP4B1 PLTP CYYR1 TPPP3 GSTP1 GATA2 FBXO16 EFEMP1 SERPINE2 GSTA3 CETN2 FAM189A2 MYLK CETN3 GJB7 RSPH10B CELF4 CAPSL LCA5L SELM TAGLN3 ALOX12B ADORA1 IL13RA2 ESRRG C6ORF52 RSPH4A EDNRA SAMD15 FAM166B GLB1L2 C20ORF96 BAMBI FAM161B EMC4 CIB1 DLG2 WDR54 FAM60A SCG5 IRX5 NUDC CLHC1 WFDC3 MNS1 C15ORF65 PIR TMEM139 MEIG1 IFT46 TCTEX1D2 PSD3 PAQR5 UNC13C GCA PDK4 RIIAD1 CCDC153 RTDR1 FAM161A CLDN8 TMEM212 LRRC23 GCHFR FAM92B SPNS3 SNX20 TPGS1 C2ORF40 ISOC2 TNN VMO1 RP1 FCAMR APOBEC4 VNN1 SLC51A GOLGA6A CLGN AGR3 GYPC CD1B MT1X ARL13B IFT74 TRHDE CCDC42B KIF1A MEIS2 CRIM1 CCDC173 CCDC160 CTNNAL1 PLSCR4 CBR3 PTGS1 LAIR2 CCDC178 GRAMD2 CACNA2D3 TMEM255B TCEAL2 FCER1A PIWIL2 KRT74 RSPH1 C4BPB C1ORF87 BEST2 HPD SLC6A13 CCDC34 FCN3 ZDHHC11 HLX FAIM ABCB11 AIG1 CSRP2 MPST ISL1 RPGR TSPAN1 C14ORF132 DYNC2H1 KCNJ2 FILIP1 TEX9 HLTF IFT81 LRRC49 TMEM91 MATN2 HOXB6 MARCH4 P4HTM TRAPPC6A METRN PIM2 MDH1B PPDPF SH3YL1 CST6 OXT ACTN3 PIH1D3 STMND1 BMX CMBL RNF183 ZBBX ARHGEF37 FXYD3 INHBB SRD5A3 CSMD1 FANK1 FSIP1 AK9 TTC26 FAM227B MAP1A DNAH5 ABCA5 LTBP1 DNAH9 ABCA10 KIF6 TTC36 SCGB1D4 BIRC7 PIH1D2 SPAG8 KIF9 AK1 ACSF2 GCSAML MOK CAPS PACSIN3 DPCD MAOB RIBC2 STRBP TLL2 LCA5 ZBTB7C TUSC3 FAM228B IGF2BP2 PDE3A CLEC11A MACROD1 ECI1 MAGIX MYCBP SPA17 SEMA3D ARHGEF9 ACADL ECI2 FGGY C7ORF57 SPAG17 CCDC146 C21ORF59 DNAH12 FAM177A1 OVOL2 ANKRD37 DNAL1 HSD11B1L UPF3B TNXB FAM47E ULK4 TSNAXIP1 C11ORF52 MAP9 CCDC39 IQCD C16ORF55 MED11 SPSB2 CCDC103 TTC25 NPHP1 EFCAB2 CCDC176 HAGHL LEPREL2 C1ORF173 SPEF1 CLIC6 FAM154B TTLL6 ODF2L UBXN10 PCDP1 CEP41 TMEM175 RAB17 CDS1 TENM4 AZI1 CGB CAPN9 SLC25A18 SEC14L3 SCGB2A1 WDR66 ALDH3B2 BEX5 C1ORF158 MORN1 BCO2 LY6K CCDC122 DAW1 ICA1L FBXO15 ZNF229 CCDC74B CCDC181 KIF27 AK7 RSPH9 NSUN7 LRRC46 CALML4 LEKR1 C9ORF135 LRRIQ1 KLHL32 SPEF2 C7ORF41 PFN4 FBP2 C14ORF37 PACRG CCDC154 LRRC6 ARMC9 C10ORF107 KAZN MYADML2 TCTEX1D4 TTLL10 TTLL9 ALS2CR12 SLC6A16 CHCHD5 IQCA1 C22ORF15 DYDC2 C2ORF50 C8ORF47 PAPPA2 GMNC ZC2HC1A C5ORF38 MORN3 NEK11 C7ORF63 FAM221A TEKT1 CCDC148 CCDC33 EFCAB1 C1ORF192 PIFO TEKT2 NME9 C5ORF49 WDR16 WDR96 DNAH11 IQCG WDR93 C9ORF117 NEK5 FAM81B CDADC1 EMR3 MS4A8B C12ORF40 CCDC13 C9ORF174 IRX3 C20ORF201 CHRNA9 CXORF57 CCDC151 C2ORF62 KIAA0825 SSPO C11ORF88 CD1E C1ORF100 HTR4 CCDC11 CAPN11 DYDC1 C1ORF177 C1ORF168 AWAT2 SCG3 CCDC19 CIB3 DNAH6 CD164L2 CCDC67 MC3R DPRX NTN5 LRRC36 MAK KIAA1407 TTC16 C9ORF9 MORN2 GAS2L2 SMKR1 EFHB SPATS1 C1ORF228 CCDC164 SAPCD1 WDR52 NRG2 PROSC C2ORF70 PPP1R42 C1ORF141 UNC13A REM2 SPATA17 C10ORF67 AGBL4 FAM194A CCDC65 PCDHB4 C15ORF26 ARMC3 SLC25A14 PLIN5 C1ORF189 PRSS54 RABL2B SEPT5 CDK15 TSPAN19 C8ORF34 C11ORF16 LRRC34 DNAI1 LRRC48 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 UHRF1 BIRC3 DPP4 CCL5 CMA1 TMEM37 MALL VDR ICOS DDX58 CXCL10 TLR4 CTLA4 PLA2G2D NDRG1 TREM2 OAS1 FN1 FASLG STAT1 PDE4D TMEM176A EIF2AK2 PLD3 CD7 FYN APOBEC3G OASL CRTC3 MOV10 ISG15 SRC VSIG4 CXCL9 FRMD8 EDEM1 IL10 MX1 MYD88 CEACAM6 ASS1 OLFML2B TM4SF1 IFI27 SLC40A1 ECM1 ZC3H12D RPS15A AQP5 RAI14 FOPNL HIST1H1E CD180 APOBEC3A ZEB1 CYBRD1 RGL1 GPRC5A HTRA1 CEACAM5 CCL8 PLA2G7 HIST1H1D MDM2 TMEM184B LSP1 GSK3A PARP10 TOR1B MYADM EFTUD2 APOL2 SLAMF8 ITGA5 SLC38A7 MYBL2 TOP2A ZNF100 CDCA8 CCNA2 EZH2 CCNB2 NREP KCNK13 SHCBP1 TMEM106A KIF18B NUF2 IFI44 FLT3 CDCA5 ADAP2 LHFPL2 FKBP5 STARD13 TNFRSF17 KIF2C MZB1 AURKA DLGAP5 BUB1 ZBTB32 RRM2 SLC1A3 MAFB BIRC5 EPSTI1 HGF MCM10 CCR2 BRCA2 IGLL5 PADI2 ANLN NCAPH EPS8 CEP55 CDC20 KIF23 TTK MKI67 CDC45 DTL GNPDA1 CD247 CCR9 SH2D2A RUNX3 A2M IGFBP3 SLC2A6 NOTCH1 ZFP36L1 SLC2A5 ZFP36L2 MPEG1 FOXM1 LAD1 SLC7A5 COL1A2 CXCL13 LMX1A LAMP1 TCF7 F2R RNF26 UBE2Q2 DHX34 HELZ2 CENPN KLRD1 CXCR3 RSAD2 OAS3 GSG2 IL10RA IRF7 GNG2 FBXO5 SELPLG NKG7 ESCO2 DENND1C FANCI ZBP1 AOAH SEPT1 TCF19 SH2D1A CHAF1B CD28 TAP1 FAM83D GFI1 NCAPD2 MS4A6A SLC29A3 CD27 IGJ LCK IL2RB KNTC1 CD160 PIK3R5 GZMA TACC3 IFIT1 FAM26F RACGAP1 MELK CORO1A TRAIP CCNF NCAPG2 CCR5 CD2 GZMK UBASH3A PTPN7 GPR171 PSAT1 IFIT3 CD84 IFIT1B CDT1 LRP8 SLC7A8 OAS2 CD86 C3 XAF1 APOL6 COCH GINS1 DHX58 USP18 CMPK2 IFI16 SEPT3 COL3A1 PREP HERC6 IFIH1 SFTPB PML ADAR RASA4 PARP9 GBP6 HPSE LIPG SLC39A14 TRAFD1 SAMHD1 PCOLCE2 TTYH3 THBD SGK1 CDC42EP1 CTSH MGP IFI44L SERPINB9 TMEM176B DDR2 GIMAP8 GIMAP4 PDPN IGFBP7 GNS NRP1 MARCKSL1 CYP2S1 FSCN1 CCND2 CYTIP TLR6 PLA2G4C MUC1 GPR157 C1ORF233 SH2B3 MAGT1 SEC61A1 GALNT7 ZW10 TNFRSF21 SEC23A GNA13 ODC1 NCOA4 ZMAT3 APOBEC3C SAMD4A GZMM LRRN4 MCM6 GRAMD4 PRF1 SLFN5 IL15RA MB21D1 SMOX SELL TRIM5 F13A1 RASD1 NCKAP1L PIK3CG SLAMF6 GIMAP1-GIMAP5 FAIM3 CXCL11 SLC43A2 PVRIG IFI6 MCM4 SLC20A1 LAMP3 DDX60 IDH2 C9ORF91 PRPS2 MX2 IFIT5 HERC5 TMEM140 SAMD9 SLC47A1 CKAP4 GJB2 ACOT7 LPCAT1 KLHDC7B CDK17 RELB CHST15 NFE2L3 TMEM62 C1S IL18R1 RAB8B NMU AZU1 PRTN3 SNN CSF2RB CCR7 PRKCH GZMB GNLY ITK P2RY10 PDE7A FLRT2 PTPRE GRAMD1B OLFML3 SDC3 ENPP2 SLC16A10 RDH12 CARD11 P2RY8 APBB1IP RHBDL3 IL21R GNA12 IRAK1 RAB35 APOBEC3F SIGLEC14 AQP9 NPC1 MRAS TNFRSF1B TIMP3 TXNDC5 PLBD2 PDCD1LG2 ARAF WIPI1 SLC35A4 SEC23IP NNT MCFD2 CDC42SE1 SLC46A2 TPCN1 ST3GAL5 RAB3IL1 MTA2 HIRA FAM118A ERAP1 SLC39A8 GAL MFSD12 RNF185 WIPF1 LILRA1 TPP1 JAK3 SYN1 PARVB SLC38A5 CTPS1 PPP1R16B SGPL1 TNFRSF11A CPM ABI3 PITPNM2 BCL2L11 GPC1 SLC9A9 CMKLR1 FPR3 FOXP3 UBIAD1 VCPIP1 TREML2 HRH2 HAVCR2 PTGIR GIT2 SMU1 IMPDH1 SLC15A4 SLC23A2 CBLB SGPP1 ALDH1A2 KCNIP3 NUP205 MCMBP ST8SIA4 UBP1 SH2D3C DSE SNX19 ARHGAP17 SEC24D EPS15L1 FGD6 CENPT HHIPL1 ZP3 GNA15 ARHGEF6 VANGL2 SULF2 LPCAT3 LRRC8C CHST11 CNP LIN54 USP38 INTS7 PPFIBP2 SLC35F6 PANK3 LPAR5 TTC39C PCTP HIST1H3F GIMAP6 GRAP SCN1B PLK4 TTYH2 ALDH18A1 ERP27 SUSD1 PROSER1 MPP1 HELB ERO1L PRKCQ ASPHD2 RAP2A GPR126 TMEM184C FBXO30 MTMR4 C2CD4B SLC22A31 TCP11L1 PLXNC1 TMEM206 SLC43A1 MTPAP MUC12 CHST12 ZNF695 DLEU7 ZNF101 ZNF586 KIAA1199 IL12RB2 SLA2 KIAA0226L HSDL1 TMEM255A PARP15 APOBEC3H GGT5 KLRC3 PYHIN1 SIRPG CDYL2 TIGIT MARCH1 SLC24A6 STARD8 ZNF417 C10ORF76 LEPREL1 KIAA1467 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CEP112 GCC2 NINL WFIKKN1 BAIAP2L1 TPRN LRRC66 USP2 TM4SF5 AGT CLIP4 CSNK2A2 AKAP9 PKIG SAT2 PTTG1IP ENKUR CYP2F1 TMC5 TFF3 OSBPL6 KCTD1 ARL3 BMPR1B ALMS1 MUC15 MT1E NEK10 KIF21A C9ORF116 PKP4 MAP3K19 TOX3 NFIB SPAG16 PAWR SOX2 USP51 C9ORF24 OTUD7B CRCT1 DYNLRB2 FMN1 MAPK10 FAM183A MORN5 GSTA1 C2ORF73 PTPRZ1 ANK3 MAP7 FMO2 WDR78 AQP3 ENPP4 DDRGK1 GPD1 RNASE2 MT1F CES1 SLFN11 B4GALNT3 LRRC43 CA11 CPA3 CRIP2 SLC25A29 PDZD4 DZANK1 BAD AVP HINT2 CDH1 BDNF AR KIAA1522 JAG2 CLDN3 ARHGEF16 WLS FGF12 CBLN4 WNT5B SOX6 SORCS1 CCDC170 CMTM8 MAB21L1 PTPRU ST6GALNAC2 QPRT CLEC5A PPM1N FABP4 COX7A1 RETN TNNI3 KCNA1 CDH26 EFCAB11 DCDC5 RAMP1 APOC2 SHANK3 CYP4B1 CYYR1 TPPP3 GSTP1 GATA2 GDPD3 NGFRAP1 FBXO16 WBP5 FIGF CRIP1 LIMCH1 PRDX5 S100A6 GSTA3 CETN2 FAM189A2 SOD1 C19ORF59 FHAD1 MYLK UPF3A IGFBP5 SCAND1 S100A13 GJB7 CELF4 LCA5L SELM PNLDC1 DNAH1 C6ORF52 RSPH4A EDNRA ANO3 TMEM52 FAM166B PABPC3 PROC C20ORF96 FAM161B ANP32A EMC4 CIB1 NKAP DLG2 WDR54 SCG5 AMIGO2 IRX5 KIAA1683 GP1BB TTC32 CNFN MNS1 C15ORF65 PIR TMEM139 MT1H TCTEX1D2 PAQR5 TMEM121 S100A8 RIIAD1 CCDC153 FAM161A GCHFR SPNS3 PTGDS TPGS1 C2ORF40 ISOC2 TNN BFSP1 VMO1 RP1 VNN1 GPRASP1 SLC51A AGR3 CD1B KIAA1211 ARL13B CEACAM7 SEMA3E IFT74 TRHDE TMEM107 CCDC42B KIF1A ARMC2 CCDC173 DEGS2 CCDC160 CTNNAL1 CBR3 BTC SERF2 PTGS1 CCDC178 PIK3R3 NAPEPLD IL17D FJX1 CACNA2D3 ERBB4 TMEM255B PAMR1 TCEAL2 RSPH1 C4BPB BEST2 HPD CCSER1 CCDC34 FFAR4 BDKRB2 FCN3 ZDHHC11 HLX IGF1 FAIM COX19 ANKRD18A AIG1 CSRP2 MPST TSPAN1 DYNC2H1 THBS3 FILIP1 TEX9 HLTF IFT81 TMEM91 MATN2 HOXB6 MARCH4 KCTD15 METRN SMIM5 MSI2 DNAH7 PPDPF TSPYL2 RBFOX2 PDGFA ZFYVE9 CST6 SLC14A2 GRK5 OXT STMND1 ZBED5 BMX PLXNB1 LIN7B TMC1 SPINK7 SERPINI2 PRSS12 MLLT4 CHD6 FXYD3 INHBB FANK1 TRIQK FSIP1 AK9 FAM227B FAM9C ARHGEF38 SLC47A2 ZNF749 ENPP1 DNAH5 ABCA5 LTBP1 PCYT1B DNAH9 TTC36 MCF2L2 GLTPD2 SCGB1D4 BIRC7 KIF9 ANTXR1 ARHGEF26 ACSF2 TOMM7 USP31 MOK CAPS DNLZ MRPS21 TLL2 LCA5 TMEM99 RNPC3 UBN2 ZNF607 CMYA5 FAM171B FAM228B IGF2BP2 ZC3H6 TECR SVIL STX2 MACROD1 MAGIX BAZ2B TCHP PPP4R4 ZNF428 SPA17 ARHGEF9 ACADL RASSF9 CAP2 SGCB C19ORF44 C7ORF57 SPAG17 CCDC146 C21ORF59 AES DNAH12 WDR60 FAM177A1 CCL15 OVOL2 PDE4C ANKRD26 ANKRD37 DNAL1 HSD11B1L UPF3B FAM134B TNXB CSPP1 FAM47E TSNAXIP1 C11ORF52 CCDC39 MED11 SPSB2 POLR2I LSMD1 GPR124 CCDC103 TTC25 CEP164 KIAA1377 NPHP1 TRAF3IP1 EFCAB2 CDKL2 CRYBG3 HAGHL C1ORF173 CLIC6 SPATA6L TMEM175 RAB17 USP46 TENM4 KIAA1841 AZI1 LRRC71 CGB CAPN9 DNAH2 SEC14L3 SCGB2A1 WDR66 CCDC125 ALDH3B2 CXXC4 SDK1 OFD1 BEX5 MORN1 BCO2 CCDC122 FBXO15 ZNF229 ACVR2B CCDC181 AK7 RSPH9 NSUN7 C9ORF135 LRRIQ1 SPEF2 C7ORF41 LRRC6 KAZN TCTEX1D4 FAM184A FAM184A NPFF TTLL9 ALS2CR12 SLC6A16 PEX11A CHCHD5 IQCA1 C4ORF17 DYDC2 C8ORF47 FER1L6 OPRL1 PAPPA2 GMNC ZC2HC1A MORN3 NEK11 C10ORF35 C7ORF63 ZMAT1 CCDC148 TTC18 CCDC33 CCDC147 WDR96 DNAH11 WDR93 C9ORF117 FAM81B CDADC1 HDGFRP3 MS4A8B C12ORF40 MNF1 C9ORF174 IRX3 AHSP CHRNA10 C20ORF201 ZNF688 CCDC151 C2ORF62 LRRC24 KIAA0825 SSPO PLEKHG4B RGS13 C11ORF88 CD1E DYX1C1 PTPN20B C1ORF100 CCDC11 DYDC1 CFAP99 C1ORF168 CCDC37 AWAT2 C2ORF71 CCDC19 CIB3 CD164L2 CBY3 DPRX CCDC113 MAK KIAA1407 TTC16 MORN2 GAS2L2 EFHB TTC40 C1ORF228 CCDC164 SAPCD1 WDR52 ACYP1 DNAJB13 CCDC108 C17ORF66 PPP1R42 REM2 SPATA17 C3ORF70 C1ORF101 FAM194A C8ORF34 DNAI1 GSDMC C2ORF66 CCDC41 PPAP2C C11ORF93 EFCAB6 CATSPER3 BEST4 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MAOA CANT1 UHRF1 SYVN1 DPP4 TMEM37 TMPRSS2 MALL SPINK1 PDCD1 CHPF THY1 ICOS TMPRSS4 SLC5A1 ACSL3 PIGO TCN2 SLC27A4 TP53 TMPRSS11A PDE4D TMEM176A TLE1 SFN RETSAT PLD3 CLCA1 CD7 SRC VSIG4 CXCL9 FRMD8 MXRA8 PCMTD2 PCSK7 METTL7A ISLR BPIFB1 CEACAM6 SERPINB11 KRT5 CP SDC1 ITGA2 FAM114A1 KRT7 PIGR ASS1 OLFML2B MSMB TM4SF1 KRT4 KRT17 TTC39A RPS15A AQP5 RAI14 UPK1B DUOX2 KLK11 FOPNL HIST1H1E CCNO TNS4 CYBRD1 KRT15 CLCA2 RGL1 GPRC5A HTRA1 CEACAM5 GABRP MDM2 TMEM184B MPZL2 PARP10 TOR3A GSN ABCC3 PLK1 SLC38A7 TOP2A CCNB2 FKBP9 GTSE1 UBE2C FZD2 NREP SLC16A1 NEK2 SHCBP1 MGST1 NUF2 FLT3 IGFBP2 MZB1 DLGAP5 BUB1 RRM2 SLC1A3 CDK1 PAQR4 POLQ KIFC1 SAPCD2 HGF SPRY2 KIF15 BRCA2 PADI2 ANLN OLFML2A NAGA CDC20 PKMYT1 TTK MKI67 ARL4C UPK3B YPEL1 GATA3 IGFBP3 BMP7 SLC2A6 NOTCH1 ZFP36L1 COL1A1 LAD1 MLPH GPR87 CBLC ENTPD2 KRT14 SEMA3F C1ORF106 SERINC2 TSKU CDH3 PROM2 DSG3 EPHB4 COL1A2 LMX1A SLC5A8 TCF7 SHISA2 KRT13 PRC1 RNF26 UBE2Q2 SLC24A3 SCAMP4 DHX34 CBX4 ZNF385A CXCR3 ARHGAP11A OAS3 KLRC1 NKG7 FANCI TCF19 C17ORF53 CHAF1B FAM83D NCAPD2 SLC29A3 CD27 IGJ IL2RB PIK3R5 GZMA PBK RACGAP1 MELK CCNF NCAPG2 GZMK GPR171 GSTA5 PSAT1 CDT1 C3 COCH GINS1 KIF18A SEPT3 COL3A1 DHFR PREP SFTPB IGFBP6 PML TINAGL1 PTGES HPSE SLC39A14 ANGPTL4 EPHA1 TTYH3 SPARC CDC42EP1 NPNT SFTPA1 IFI44L PLSCR3 SERPINB9 TMEM176B ARRDC3 C10ORF10 S100A16 LIMD2 CYP2B6 MARCKSL1 CYP2S1 FSCN1 PDZRN3 PRSS36 NOS2 KCNE4 FUT2 LYPD2 PGLYRP1 COL20A1 NAPSA SNCG RTN4R RADIL FOXK1 MUC1 ADRA2A C1ORF233 GALNT7 STK39 SLC25A15 SMIM6 TNFRSF21 DHRS2 LRP11 HSPA2 SOAT1 ADORA2B E2F7 CNN1 ID1 MN1 COL7A1 SAMD4A IP6K3 GZMM PRRX2 DOK4 OTX2 LRRN4 ZCCHC12 PCYOX1L GMDS APBA3 GRAMD4 PRF1 FAM57A STRA6 AVIL SLFN5 MMP13 SMOX SELL NRARP SLC16A12 SLAMF6 FAIM3 SLC27A1 SLC43A2 IFI6 FAM171A1 IDH2 CKAP4 GJB2 PAPSS2 ACOT7 LPCAT1 REEP4 KRT16 MAP10 NFE2L3 MDK TMEM62 C1S NMU GZMB GNLY ADD3 ST6GAL1 PDE7A FLRT2 KRT6B GRAMD1B FHL2 ITLN1 FADS2 APBA1 SDC3 CXCL14 DSC2 LAMA3 ENPP2 KRT6C ITGB6 KRT6A CDC20B KRT24 ABO CGA PTPRR NPTX2 COL25A1 SH2D6 MAST1 LPO KRBOX1 APOBEC3F SIGLEC14 LIPE TIMP3 TXNDC5 PLBD2 FBLN1 NNT SLC46A2 SLC25A10 ORAI3 XPNPEP3 TPCN1 CHST4 CHST10 POLH MTA2 HIRA CLDN1 SOCS6 SLC39A8 CDH4 TRIP6 HAPLN3 HECTD3 GAL MFSD12 JAK3 KLK10 SLC38A5 VSIG2 UCK2 SGPL1 RPS6KA4 PRSS8 TNFRSF11A MUC2 ELAC2 ABCC10 CYP3A5 BHLHA15 FER1L5 GSR SLCO1A2 NOTCH3 GPC1 SLC19A1 PCDH17 CMKLR1 ATP13A2 LUM SCARA3 PLD1 FANCC ULBP2 IMPDH1 GJB1 HSD17B13 SLC15A4 ACSS2 CBLB CREB3L1 KCNIP3 DFFB GEMIN4 POC1A TMED3 SP2 DUOXA1 SEC24D CENPT HES6 HHIPL1 ZP3 DSC3 MTSS1L FAT2 SULF2 RAB15 PADI3 LY6D UST FAM198B LPCAT3 ZNF672 IGFBPL1 GPRIN2 ATRN CDR2 PPFIBP2 ZNF598 PADI1 GPR161 NIPAL3 FBXL18 NDST2 SLC25A51 APBB1 OAF EHD3 GRAP DGKA GAN RAB3D PLK4 TTYH2 BPIFB2 RBP1 SLC35G1 PDXP ALDH18A1 ERP27 DFNA5 FAM109B TBC1D24 DBN1 RDH10 ASPHD2 PMEL CCDC87 PVRL2 SOGA1 SOGA2 TMEM184C LMBR1 SLC22A31 SEMA5A SLC43A1 FOXN4 SH3RF3 EPHX3 MTPAP RBM44 CERS3 MUC12 PRICKLE4 SHISA8 SLC35F2 DLEU7 RNF39 BAIAP3 PTPRG ZNF586 NRSN1 MFAP2 NPFFR1 HMSD EVC MOXD1 ZER1 IL12RB2 LGALS7 ZNF354C EVC2 SLA2 MTL5 CACNA2D4 SLC4A11 C16ORF89 TMEM255A CCDC36 PPT2 PYHIN1 C14ORF169 CCKBR TIGIT C8ORF42 NPIPL3 STARD8 C10ORF76 LEPREL1 KIAA1467 UPK3BL ZNF829 MCIN MYO3B CT62 LEPREL4 KDELC2 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 RSRC2 PFAS CISD3 KPNB1 TSPO DDX21 ACE2 IL17RD UBXN1 ECSIT TBX10 KLF6 MRPS5 RYBP BAIAP2L2 AGT FAU AKAP9 PPIG DCAF7 USP7 RAB5C AGBL3 NOL7 VAMP8 SAT2 GADD45GIP1 CABLES1 FGFR4 ARHGAP18 PTTG1IP CACNB4 EXOSC4 RPS6KA5 XPA PFDN5 ARL4D UQCR10 THRB MT1E KIF21A C9ORF116 GATAD2B MAP3K19 COX6A1 CRCT1 MAPK10 FAM183A MORN5 ACOT13 CRNN AIF1 RPS7 BANF1 ENPP4 INPPL1 HBEGF EMILIN2 PRAM1 APH1A ITPKB TMED9 MRC1 SAP30 RNASE2 RAB13 NUDT16 MAFG CD163 FCRL5 LTA4H SLFN11 PTPRO IFI27L2 LRRC43 NCR3 NCALD CAMP STAC AVP CISH HPGDS EDN1 PLAUR AR CBLN4 JAG1 SAFB CCDC170 OR2A5 ZNF865 CYHR1 TBL1X GPR162 QPRT PYCARD TNFRSF9 CLEC5A EMR1 PPM1N CLEC4A LY86 FCER1G PON1 FABP4 COX7A1 CCL24 RETN CCL17 CLEC6A CLEC4E PLAC8 CLEC4D RAMP1 PLEKHA4 GLIPR2 INHBA PTPRT APOC2 TRIL CHMP4B COX17 CYYR1 TXN DTX3L SYF2 U2AF2 JUN CHCHD2 CA2 NGFRAP1 FBXO16 WBP5 S100A4 COX7A2 GPAM SNRPD2 RPL22 PRDX5 ARL6IP4 C19ORF43 NUPR1 CETN2 NDUFB7 RGCC SEPW1 NDUFA2 SOD1 TRMT112 NDUFC1 C19ORF59 MYEOV2 ALOX5AP NDUFA6 MBLAC1 TNNI2 USMG5 ATP2B1 USHBP1 UPF3A C8ORF59 SCAND1 TMEM256 LST1 DDIT3 STARD9 TBX3 PNLDC1 EGR2 BEST1 IL27 HSPA6 ALOX12B SERPINI1 ADORA1 B3GNT5 C6ORF52 RSPH4A SOCS2 EDNRA ZNF292 PROC C17ORF96 IER5 FAM161B TMEM258 ANP32A DPM3 LAMTOR2 EMC4 ACIN1 CIB1 C7ORF55 PFDN2 COPRS TTC1 LSM7 UQCRQ TOMM34 EMG1 C2ORF74 RPAP3 HMGN3 FAM60A ERH CBX1 STAG2 HSPE1 CNFN CLHC1 TMEM170B WFDC3 HNRNPA0 MNS1 C15ORF65 ATP5E TCTEX1D2 TMEM121 ANKRD55 S100A8 GCA RIIAD1 CCDC153 PIGZ GCHFR SNX20 PTGDS BATF3 DGAT2 TNN NUDT1 GYPC CD1B PIRT ARL13B SEC62 IFT74 TRHDE TMEM107 KIF1A SMIM10 CCDC173 CCIN ETS2 RBM34 SNX12 MOB3C SERF2 MYL6 CNPY3 PTGS1 TCEB2 FOLR3 LAIR2 CCDC178 IGIP HRH1 IL17D PPFIA4 CLK1 AIM2 TMEM255B TRPM3 C4BPB BEST2 HPD AKAP7 FFAR4 PTPN1 ANAPC11 GTF2H5 PET100 TRAPPC5 FGR C19ORF38 CARD16 FAIM ERP29 NDUFB1 ZIK1 ZNRD1 GSTK1 IRAK3 CDC42 CGGBP1 CCL18 C19ORF53 BLOC1S1 LTB4R CSRP2 MPHOSPH8 FFAR2 TSPAN1 EML4 NSRP1 RBBP6 U2SURP RPF1 FILIP1 CEBPZ WBP4 TEX9 MRPL33 CWC15 ATXN1 TMEM91 MATN2 HOXB6 ITPA TRAPPC6A GMFG EIF1B RTN3 PPDPF RNMT EPC1 SNAI1 AMOTL1 GRK5 OXT PIH1D3 STMND1 ZBED5 LIN7B TMC1 SPINK7 SYCE3 OTOA MPHOSPH6 PRSS12 INHBB AK9 FAM9C USH2A MSRB3 CD1D FIS1 CPT1B POLR2F ADIPOR2 FGD4 ZNF197 HYPK ENPP1 MTHFS GPR82 LTBP1 DNAH9 SHOC2 TTC36 ABCA6 IGFALS FAM151A SCGB1D4 BIRC7 USE1 TCL1A RNASEK MGST3 MRPL23 DYNLRB1 TOMM7 GCSAML DLC1 DNLZ MAOB ANXA6 MRPS21 S100A7 CMYA5 FAM171B KCNH1 SVIL PBDC1 ECI1 CCDC174 TP53I13 MAK16 FOXN2 ATPIF1 SLC25A30 NAA16 SSPN JOSD1 ZC3H13 FRG1 PDCD5 SPA17 MGST2 C1RL ACADL HAL CARD9 RASSF9 ZRSR2 CNTLN CDC5L PGM5 LSM6 PLA2G16 AES TMEM120A FAM177A1 CCL15 MINOS1 ANKRD37 NKTR C17ORF89 PODXL2 FAM213B UPF3B CCDC39 MED11 AP1S2 KIAA1430 POLR2I LSMD1 NPHP1 CRYBG3 ZNF658 LEPREL2 C1ORF173 KCNN3 TMEM175 KIAA1598 POP1 KRT40 CGB YRDC SEC14L3 MRPL53 SCGB2A1 MALSU1 ZNF823 SLC25A19 CCDC125 ALDH3B2 OFD1 MORN1 CCDC122 PAK3 TRIM44 NUDT18 CDK3 FAM200B CCDC181 ZGLP1 GSG1 ZNF589 C9ORF135 KAZN CDH23 UPF2 FAM212B WIPF3 SLC6A16 SLC24A1 CHCHD5 IQCA1 C4ORF17 DYDC2 C8ORF47 PAPPA2 MORN3 CCDC148 MTCP1 PGBD1 EMR3 C12ORF40 MNF1 C20ORF201 CHRNA9 ZNF688 C11ORF83 MAMU-DRB1 CCDC151 KIAA0825 SSPO RGS13 C11ORF88 CD1E C4ORF27 C1ORF100 C1ORF168 RIMBP2 AWAT2 SCG3 CIB3 CD164L2 MC3R DPRX ACYP1 CEACAM4 EBF3 PROSC CATSPER3 C1ORF123 ZNF583 FAM165B Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FOXRED2 DCAKD SLC5A2 DPP4 CMA1 TM6SF2 AADAC ICOS PLA2G2D COL4A1 SLC5A1 ACSL3 PIGO ZYG11B TREM2 TCN2 SLC27A4 DMBT1 COL4A2 TLE1 RETSAT PLD3 CLCA1 CD7 CRTC3 TTC38 VSIG4 SCARB1 KALRN FRMD8 ERC1 DHTKD1 NFS1 PCMTD2 KDR METTL7A ALDH6A1 CPT1A CDK5RAP1 TMEM86A BPIFB1 SERPINB11 PIGR SPATA5 ASS1 TM4SF1 KRT17 SLC40A1 TTC39A RPS15A AQP5 RAI14 UPK1B KLK11 FOPNL HIST1H1E CCNO CD180 TP63 CYBRD1 CLCA2 GPRC5A HTRA1 CEACAM5 PLA2G7 SLC25A23 TMEM246 GABRP MDM2 TMEM184B SYMPK OGDH PNPLA2 ADCY7 TOR1B H6PD MYADM INF2 ABCC3 SLC38A7 ZNF100 FKBP9 NREP ADAM15 KCNK13 MARVELD1 FRRS1 FLT3 STARD13 OLAH FGD2 DLGAP5 BUB1 RRM2 SLC1A3 HGF SPRY2 CCR2 BRCA2 ALOX15B MYO7A PADI2 OLFML2A NAGA CDC20 UPK3B MYH11 IGFBP3 BMP7 SLC2A6 ZFP36L1 CDYL WDR72 B3GNT9 MTOR MLPH ENTPD2 C1ORF106 CDH3 PROM2 SPDEF MCCC2 FRAT1 ALPL WNT2B LMX1A SLC5A8 TBC1D8 FOCAD BMP1 RNF26 SLC24A3 SCAMP4 DHX34 AP5B1 OAS3 FANCI FAM83D IGJ PIK3R5 GZMA GP2 RACGAP1 TRAIP CIDEC GSTA5 SLC7A8 OAS2 C3 COCH GINS1 GDPD2 SEPT3 COL3A1 CD177 PREP CCDC129 PML EPHA1 PCOLCE2 SEPT4 EPAS1 SPARC CDC42EP1 NPNT ADAMTS15 MGP IFI44L ARRDC3 PDPN CYP2B6 NRP1 MARCKSL1 CYP2S1 PDZRN3 NOS2 CPT1C FUT2 MXRA5 RADIL MUC1 CLN8 GPR157 ADRA2A C1ORF233 TOR4A GALNT7 SMIM6 TNFRSF21 LRP11 HSPA2 ATP2C1 SOAT1 PLEKHH2 ZMAT3 E2F7 DQX1 SAMD4A KRBA2 C19ORF54 DLG4 IP6K3 GZMM CLIP2 PCNXL3 LRRN4 ZCCHC12 PCYOX1L SNX15 GRAMD4 PRF1 FAM57A PNPLA3 AVIL SLFN5 PP2D1 RASD1 SLC16A12 NCKAP1L FAIM3 SLC6A4 SLC27A1 GABRE IFI6 SGK494 FAM171A1 IDH2 EOGT HYAL4 ZNF573 SLC47A1 PAQR8 GJB2 PAPSS2 P2RY1 DGKH CCDC142 SLC2A10 AZU1 PRTN3 MPO GZMB ZNF546 FLRT2 KRT6B TRIM16L APBA1 SDC3 CXCL14 ENPP2 ITGB6 CDC20B C6ORF10 CHRND ABO RHBDL3 CECR1 MAST1 LPO IRAK1 SIGLEC14 AQP9 TERT TIMP3 TXNDC5 PLBD2 LARS2 WDPCP SLC46A2 TMEM209 CCS XPNPEP3 TPCN1 CHST4 CHST10 POLH PHC3 TRMT2B MTA2 HIRA EIF2AK1 CAMKK1 TRIP6 ACAP3 HECTD3 FBXO10 MFSD12 TMEM129 C9ORF66 SLC38A5 CTPS1 SLC9A1 PLXNA2 VSIG2 RPS6KA4 PRSS8 TNFRSF11A PRKD1 CPM CHDH MUC2 MPDZ SLC22A3 ABCC10 A1BG FER1L5 SLCO1A2 PCDH17 OR1K1 CMKLR1 FPR3 PRKCG ATP13A2 LUM SCARA3 TECPR1 FANCC ZNF621 ZNF227 NCAM1 ULBP2 ABTB1 LMF1 CYP2U1 GJB1 HSD17B13 SLC15A4 ACSS2 CRAT NHEJ1 CBLB SGPP1 CREB3L1 TRPM6 ALDH1A2 DFFB XPO5 NUP205 GEMIN4 TOP3B CRTAP PLAC9 KANSL3 SEC24D FGD6 TTPAL SFXN2 CHST7 CENPT HES6 GALNT10 HHIPL1 ZP3 VANGL2 FAT2 PADI3 UST LPCAT3 LRRC8C IGFBPL1 GPRIN2 ATRN TBC1D4 PDPR USP38 CDR2 OPHN1 C8ORF82 PPFIBP2 TRIO LMF2 PADI1 TBC1D16 NIPAL3 PHKA1 NDST2 TMEM117 RBBP9 DNAH14 APBB1 RANBP3L MBTPS2 DNAJC1 P2RX7 MSTO1 GAN GFRA3 MAMSTR TTYH2 RBP1 FBXW8 SLC35G1 ATP11B PDXP ALDH18A1 ERP27 FOXE1 SLC17A5 FAM109B XPO4 TBC1D24 ALDH5A1 EXOC6B ADCK1 POLR1B CLEC16A TOP3A RDH10 HHATL CCDC87 SOGA1 POMGNT1 GPR126 SOGA2 TMEM184C ZNF559 GHDC GUCY1A2 PARK2 TCP11L1 KCNA3 SEMA5A PNMAL2 FOXN4 SH3RF3 EPHX3 SNX27 MTPAP SLC5A7 LARGE MUC12 ZNF619 MVB12B PRICKLE4 SHISA8 SLC52A1 PCDHGA3 C11ORF45 DLEU7 BAIAP3 PTPRG ZNF586 FIBCD1 IL20RA CHRNA3 AJAP1 DIS3L2 ANKRD36 EVC PYROXD2 ADAMTSL5 ZKSCAN7 SYT5 IL12RB2 ZNF354C AMZ1 EVC2 LAMB4 MTL5 SLC4A11 ASB4 C16ORF89 POLK TMEM255A DNASE2B EXD2 ZNF836 CCDC36 ZNF792 SYNDIG1 PPT2 C7ORF10 ZNF429 HIATL1 C9ORF37 KIAA0226 NEK4 CCKBR GPR77 CA5B CDYL2 SLC24A6 NPIPL3 ZNF417 C10ORF76 C16ORF96 TAS1R1 SS18 KIAA1467 UPK3BL ZNF829 MCIN CNIH2 GRID2IP ZNF879 IRGC PSG3 ARHGAP40 CATSPER4 TGM7 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 2 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SRP19 UBL5 RPS27A RSRC2 CCL2 WFIKKN1 SUMO2 CISD3 NMI KPNB1 HNF4G ACE2 IL17RD RBX1 ZCRB1 FCER2 GNG5 MRPS5 RYBP LARP7 UBA52 FAU ITM2A PPIG DCAF7 CHMP2A NOL7 PKIG VAMP8 SAT2 GADD45GIP1 NDUFB6 EXOSC4 ASB9 XPA PFDN5 RPS17 RPL37A ENKUR TFF3 MT2A KCTD1 UQCR10 ARL3 RPL27 RPL41 TPT1 MT1E C9ORF116 NME5 GATAD2B RPL38 MYRIP NDUFB2 COX6A1 RPS15 C9ORF24 CRCT1 DYNLRB2 ATOX1 FAM183A RPL19 AIF1 RPLP1 RPS7 HBEGF SNRPB APH1A ITPKB TMED9 SAP30 MT1F MCM10 RGS16 RPL26L1 SLFN11 IFI27L2 MRPL51 LRRC43 CPA3 PER3 PDZD4 ZFYVE28 EGR3 FCRL6 HINT1 BAD HINT2 HPGDS EDN1 FGF12 CAMTA1 CBLN4 SORCS1 FCN1 CD69 RGS1 CLEC4A CENPM COX7A1 TXLNB CCL17 DNPH1 CLEC6A CLEC4E PLAC8 RAMP1 JPH3 INHBA PSME1 TOX2 TNNC1 CHMP4B COX17 TXN SYF2 ATP5J GSTP1 CLIC3 NDUFA3 U2AF2 PSMB9 RPS23 CHCHD2 FBXO16 SFTPC COX7A2 SNRPD2 RPL22 PRDX5 C19ORF43 S100A6 NDUFS6 TMEM160 CETN2 ATP5H SHFM1 RPL35 NDUFB7 RGCC FAM189A2 SEPW1 NDUFA2 SOD1 ROMO1 TRMT112 NDUFC1 COX6B1 MYEOV2 NDUFA6 MBLAC1 EDF1 CFDP1 NDUFA4 CETN3 TNNI2 SUB1 USMG5 NDUFC2 CHCHD1 C8ORF59 MRPS18C PIN4 ATP5J2 GLOD4 NDUFB10 NDUFA7 SCAND1 TMEM256 COX14 MIEN1 DEK ANK1 LST1 DDIT3 SELM IL27 SERPINI1 ESRRG C6ORF52 RSPH4A HMGN5 FUS PROC C17ORF96 SERTAD1 ANP32A DPM3 SNRPG MMP10 LAMTOR2 EMC4 ACIN1 MSRB2 CIB1 C7ORF55 MRPL27 PFDN2 LSM2 DDX18 PSMB3 TTC1 IMMP1L NHP2 CDC26 LSM7 UQCRQ EMG1 ZNF593 ATP5L SSB CMC1 HMGN3 FAM60A ERH CBX1 HSPE1 SF3B5 TTC32 CNFN HNRNPA0 MNS1 C15ORF65 MCC ATAD2 ATP5E MT1H DNAJB5 RPA3 TCTEX1D2 SLIRP TCEB1 S100A8 GCA RIIAD1 CCDC153 PIGZ GCHFR SNX20 SSNA1 BATF3 TPGS1 SPIB TNN VMO1 NUDT1 CD1B MCM7 ARL13B ALYREF SEC62 IFT74 TMEM107 KIF1A EIF5B CCDC173 XRCC4 RBM34 CSTB ERAP2 MOB3C BTC U2AF1 SERF2 SEC61B MYL6 NDUFB4 TAF10 COX5B UQCR11 TCEB2 CDKN1B COX6C LTB LAIR2 CCDC178 CACNA2D3 TMEM255B TCEAL2 FCER1A PIWIL2 BEST2 CCDC34 PTPN1 ANAPC11 TXNL4A PFDN4 GTF2H5 PET100 TRAPPC5 UBE2B C19ORF38 SOX5 ERP29 NDUFB1 FKBP2 TRAPPC10 UBALD2 MAPKAPK2 ZNRD1 TP53RK COX19 GSTK1 CDC42 AURKAIP1 CMTM7 BUD31 CCL18 C19ORF53 BLOC1S1 MRPL52 C19ORF24 TSPAN1 NSRP1 CEP63 RPF1 FILIP1 WBP4 TEX9 MRPL33 CWC15 PMF1 TMEM91 HOXB6 TRAPPC6A SMIM5 CMC2 PIM2 GMFG EIF1B RTN3 PPDPF SNAI1 C19ORF48 GRK5 OXT STMND1 BMX CDC34 TMC1 SPINK7 SYCE3 MPHOSPH6 FXYD3 MSRB3 PGP FIS1 FAM133B POLR2F SCN9A EMC6 HYPK LTBP1 SHOC2 DRD2 TTC36 RPP38 IGFALS SCGB1D4 DGUOK BIRC7 SUDS3 TEF CDK12 USE1 COX7B NDUFS5 AK1 MRPL23 DYNLRB1 RNASEH2C POLR2L SSBP1 OCIAD1 TOMM7 SRFBP1 MOK MRPL41 DNLZ MRPS21 LCA5 NCR3LG1 IGF2BP2 PBDC1 MACROD1 ALKBH7 NAA38 ECI1 MRPL55 CCDC167 MRPL21 CCDC174 SNRPF ATPIF1 C17ORF49 TOMM6 SLC25A30 ZNF585A TMEM134 FRG1 COA6 C1RL MAPK8IP2 RASSF9 PHPT1 CLEC10A CCDC146 RSBN1 BARX2 COL5A3 PLA2G16 SNRNP35 AES TMEM120A WDR60 FAM177A1 CCL15 MINOS1 ANKRD37 C17ORF89 FAM213B UPF3B SDHAF1 EAPP GNG7 CCDC39 ATP5I POLR2I LSMD1 SF3B14 MRPS17 C1ORF173 CLIC6 KCNN3 TCEANC RAB17 RPP25L YRDC SEC14L3 MRPL53 SCGB2A1 ALDH3B2 OFD1 BEX5 MORN1 PAK3 ADAMTSL3 TRIM44 ACVR2B SMIM4 FAM200B CCDC181 ZGLP1 C9ORF135 LRRIQ1 CIR1 LRRC6 KAZN CDH23 UPF2 ABRA KRR1 CHCHD5 IQCA1 C12ORF65 DYDC2 C8ORF47 CCDC148 FAM81B C12ORF40 MNF1 PM20D1 C22ORF32 CHRNA10 C20ORF201 C19ORF60 KCNK12 C11ORF83 SSPO RGS13 C11ORF88 CD1E C4ORF27 C1ORF100 CCDC11 MYBPH C1ORF168 CIB3 CD164L2 MC3R DPRX SAPCD1 CEACAM4 C9ORF142 PSD PROSC PPP1R42 MRP63 C11ORF91 LYRM1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FOXRED2 DCAKD EMC1 CANT1 ERMP1 FAM8A1 SYVN1 ANPEP ERGIC1 SUN2 TRIB3 TMBIM1 PFKL ADAM9 KCNQ1 ACSL3 ZNF274 FAR2 CLCN6 SERPINE1 GGCX MID2 SLC27A4 CTSD NUCB1 FN1 ACE TSPAN8 CLCA1 MSN CRTC3 STOM TTC38 VSIG4 UBQLN2 LNPEP SCARB1 FRMD8 SIPA1L1 PCMTD2 HSD3B2 TM7SF3 RILP METTL7A FZD5 ACO1 CDK5RAP1 FECH TMEM86A NAGLU MKRN2 BPIFB1 PIGR ENTPD3 SLC40A1 RPS15A FMO3 HEY1 PTGFR SCIN CLCA2 RGL1 SLC25A23 GABRP TMEM184B POLG OGDH PNPLA2 MAN2B1 SEL1L SLCO2B1 RMDN3 ACSS1 H6PD GAA SUMF2 ZDHHC7 MYADM SH3BP2 PROS1 PLOD1 KCNAB2 GANAB EFTUD2 HK1 ITGA5 ABCC3 SLC1A5 MRC1 SLC38A7 FLVCR2 CYFIP1 FKBP9 SLC16A1 LPL ADAM15 CLCN4 TMEM38A CLEC1B CD163 SPRY2 C2 CCR2 DPYD CLEC12B SORT1 SCD UPK3B ARVCF A2M SLC2A6 MYC TGFBR2 SERHL2 ZFP36L2 PIK3IP1 MPEG1 SLC2A8 ABCG1 CTSG MLPH TSKU TPD52L1 SLC7A1 ARHGAP1 RNF26 STK40 TFE3 DGCR2 OAS3 FANCI TLR1 SLC29A3 PIK3R5 CHIT1 GP2 TRAIP ZRANB3 SLC7A8 C3 COCH GINS1 CA7 PREP PIM1 SLC39A14 C5AR1 MAMDC2 HCN1 SLC6A15 BMPR2 SEPT4 IGFBP4 TGM2 TMCC3 PTPRM NPNT SFTPA1 ADAMTS15 SCGB1A1 CCKAR HIPK3 FHL1 CYP2B6 TNS3 GNS THEMIS2 COL9A2 SLC25A25 NOS2 NCKIPSD GPRIN3 FUT2 KCNN2 COL20A1 HERC3 VASN ADRA2A TOR4A DUSP6 GYS1 SEC61A1 EPDR1 GNG12 TNFRSF21 SEC24B CHTF8 LRP11 PRPF8 ATP2C1 TTC7B SLCO2A1 PLEKHH2 NCOA4 ZMAT3 WDR11 CADPS2 C15ORF52 ZCCHC24 IP6K3 PCNXL3 CDH6 ITPRIP PIGT AVIL CSF3R ANKFY1 SLC16A12 CHAD NCKAP1L PIK3CG DGAT2 FAIM3 SLC6A4 SLC27A1 AARS IARS FAM171A1 VPS41 DDHD2 C9ORF91 NCAPD3 CAB39 SLC47A1 PPP1R3D PAQR8 GJB2 IGFBP1 P2RY1 ST6GALNAC6 DGKH CCDC142 VAT1 SEC31A NCEH1 PANX1 ACTN1 EIF4G2 ADAM10 ST6GAL1 FLRT2 CHST2 ITLN1 MMP2 SLC16A10 C6ORF10 NR2E1 ABO NPTX2 CECR1 SF3B3 GNA12 IRAK1 TYRO3 IFNLR1 NPC1 RYR1 TGFBRAP1 TXNDC5 ADPGK RAB5B PLBD2 EXOC2 STK10 TMEM43 SLC35A4 SEC23IP CITED2 BTBD1 CLCN7 CLPTM1 SLC46A2 SLC25A10 TPCN1 CHST4 LY75 MTA2 C16ORF62 REC8 STT3B SUSD2 SLC39A8 PLA2G4A PPAT CAMKK1 CYB5RL MATN2 HECTD3 BTBD9 POLR2A FBXO10 MFSD12 STK24 TPP1 PXDN MAP4 TTC7A CTPS1 SLC9A1 RAF1 EDC3 FAM214B SGPL1 RPS6KA4 TNFRSF11A PDE3B ZNF699 CPM KLF8 NFAM1 CHDH MUC2 NUP160 MEGF9 GANC KDM3A AZGP1 SLC22A3 PIWIL1 ABCC10 RDH11 HLCS IL6ST TTPA SLCO1A2 CD1D NOTCH3 SLC19A1 OR1K1 VAC14 ADAMTSL4 FPR3 ATP13A2 SPHK2 UBIAD1 PLD1 FANCC TTI1 ZNF227 ZNF45 SLC46A1 ABCA2 LMF1 TRIM35 WDR48 CYP2U1 GJB1 SLC15A4 SGPP1 CREB3L1 ALDH1A2 ANAPC1 NUP205 MCMBP NUP188 GEMIN4 TOP3B VPS8 UBP1 NUP133 GRK6 CS TUBGCP4 KANSL3 SNX19 GAPVD1 SEC24D HMG20A ELMSAN1 ARHGEF28 SFXN2 AGFG2 AFAP1 MANBA SLC44A5 MAN1C1 DENND4C FAM198B LPCAT3 MCOLN3 NHLRC3 SBF2 HSPA13 GPD1L TMEM104 GPRIN2 HGSNAT ZMIZ1 ATRN INTS7 A4GALT MED16 PPFIBP2 LMF2 PPIL2 SLC35F6 ZSCAN20 DOCK5 TBC1D16 ATL3 NDST2 SNTB1 SLC25A51 TMEM117 RBBP9 TTC39C TM9SF4 HSPA12A SND1 HEATR5A DNAJC1 CIZ1 SLC12A4 MSTO1 MFAP3L OSBPL11 GFRA3 MGAT3 BLOC1S3 TMEM63A SLC35G1 PDXP ALDH18A1 ERP27 KIAA0196 NHSL1 LDLRAD3 SLC17A5 CHAMP1 ALDH5A1 EXOC6B POLR1B FTO TOP3A SOGA1 SLC44A1 LRP12 SOGA2 GPR124 GPRC5B FTSJD1 LMBR1 SPIN3 MTMR4 CCDC132 ELMO1 THSD4 KCNA3 EVI5L FBXO41 DUSP3 SH3RF3 SNX27 MTPAP SLC5A7 ELMO2 MVB12B PRICKLE4 DLEU7 GYG2 ZNF846 MAN2B2 CHRNA3 PHF17 EVC MEST PTPN9 ADAMTSL5 ST6GALNAC3 ST6GALNAC3 GCN1L1 ZKSCAN7 EVC2 C16ORF89 SEPN1 FAM211A DNASE2B EXD2 ZNF836 AHSP PRR18 C9ORF106 HIATL1 XG CA5B SLC24A6 STARD8 C16ORF3 C10ORF76 TAS1R1 SS18 DYM UPK3BL SH2D4B PSG3 ERV3-1 EMID1 GPR149 TBC1D13 TANGO6 C6ORF15 Top 500 downregulated genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SRP19 UBL5 BIRC3 GCC2 WFIKKN1 RPL12 SWI5 SLC16A8 IFITM1 RYBP LARP7 TREH USH1C FAU ITM2A USP7 NOL7 H2AFJ GADD45GIP1 MNAT1 XPA OCIAD2 PFDN5 NMB RPL37A ENKUR TNFSF10 UQCR10 IFI27 ARL3 RPS11 RPL27 MAL RPL41 HOPX C9ORF116 GATAD2B SPAG16 COX6A1 RPS15 C9ORF24 CRCT1 DYNLRB2 ATOX1 FAM183A TFF1 MORN5 CRNN AIF1 RPLP1 RPS7 C1QC STMN1 C1QA HMMR MT1F UACA RGS16 ADAMTS2 SLFN11 IFI27L2 SKA1 MRPL51 CCR3 LRRC43 CST7 NTRK1 CLC PRSS57 FCRL6 TRAT1 PLCXD1 HINT1 BAD HINT2 HPGDS BDNF EDN1 FZD8 HIST1H4G SETD1B CD69 RGS1 BARD1 GIMAP7 IL18BP TNFRSF9 CTSW HELLS HCST IGJ CD3D CENPM TNFRSF18 LY86 DNASE1L3 PON1 COX7A1 BEX1 S100A9 PSMB8 APOL6 EFCAB11 RAMP1 JPH3 INHBA ANGPTL4 SP110 HSBP1L1 GDF1 PSME1 PSENEN PSME2 TOX2 CD200 COX17 CYYR1 ATP5J GSTP1 GATA2 NDUFA3 PSMB9 GDPD3 COX7A2 CRIP1 SNRPD2 NDUFA13 C19ORF43 MRPL20 S100A6 NDUFS6 TMEM160 CETN2 C6ORF57 ATP5H NDUFB11 SHFM1 RPL35 NDUFB7 PSMB4 NDUFA2 KRTCAP2 ROMO1 NDUFC1 LIMD2 COX6B1 MYEOV2 NDUFA6 MBLAC1 EDF1 NDUFA4 CETN3 SUB1 MYLPF USMG5 CDK11A YTHDC1 CHCHD1 C8ORF59 MRPS18C PIN4 ATP5J2 GLOD4 NDUFB10 NDUFA7 SCAND1 TMEM256 COX14 S100A13 MIEN1 CLEC2B ALOX12B C6ORF52 ZNF292 CYP2A13 HMGN5 PROC SERTAD1 TMEM258 ANP32A DPM3 APOM SNRPG LAMTOR2 EMC4 MSRB2 CIB1 C19ORF70 C7ORF55 MRPL27 MRPS33 PFDN2 RNASEH2A PTTG1 ZNHIT1 IMMP1L LSM7 UQCRQ SSR4 SSB RPAP3 CMC1 UQCRH HOXB7 FAM60A ERH CBX1 HEBP2 HSPE1 RPL29 RPL34 MORC4 ARGLU1 TTC32 CNFN CLHC1 WFDC3 HNRNPA0 MNS1 C15ORF65 C17ORF50 MMP9 ATP5E MEIG1 CTDP1 RPA3 TCTEX1D2 SLIRP STAP2 SUSD3 S100A8 RIIAD1 CCDC153 FAM161A GCHFR SNX20 SSNA1 TMEM40 VMO1 TESC NUDT1 FNBP4 CD1B PSIP1 SEC62 IFT74 ZRANB2 TMEM107 FAM103A1 CCDC173 XRCC4 PNISR RSF1 CEACAM1 DUSP4 FMR1 ENO2 U2AF1 SERF2 MYL6 NDUFB4 TAF10 UQCR11 TCEB2 CDKN1B COX6C GNLY LTB LAIR2 LPAR6 DAPK2 HIST2H2BF FAM101B TCEAL2 GZMH PMFBP1 CCDC34 GFI1B ANAPC11 PFDN4 GTF2H5 PET100 TRAPPC5 CLECL1 CARD16 NDUFB1 FKBP2 ZIK1 ZNRD1 COX20 COX19 AURKAIP1 CMTM7 BUD31 C19ORF53 C11ORF58 CSRP2 MRPL52 TSPAN1 RBBP6 USP16 WBP4 TEX9 MRPL33 CWC15 NOXO1 SMIM5 PIM2 EPC1 SREK1 CST6 BFSP2 PLEKHF1 OXT PIH1D3 BMX SPINK7 SYCE3 PRSS21 ZBTB18 FXYD3 KRAS SMC4 PDGFB AK9 ARHGEF38 FIS1 FAM133B POLR2F SESN3 EMC6 RSBN1L HYPK EXOC3L4 CLEC2D LTBP1 DNAH9 FFAR3 TTC36 PON3 SCGB1D4 DGUOK HOXB4 GPX7 MT1G COX7B NDUFS5 PNKD MRPL23 JOSD2 PALMD DYNLRB1 POLR2L BCL7C RTF1 SSBP1 TOMM7 TNIK C6ORF222 MRPL41 DPCD DNLZ H2AFV MRPS21 LY6D CLEC11A MYRF ZCCHC14 C1ORF131 NAA38 ECI1 MAGIX CCDC167 RPL39L MRPL21 CCDC174 PAFAH1B3 SNRPF ATPIF1 LSM5 PRRG4 NAA16 MED19 CCDC171 PDCD5 COA6 SYNJ2BP-COX16 LRRCC1 SPA17 C1RL SLC7A2 DDX6 EAF1 PHPT1 C1ORF35 C7ORF57 CCDC146 ADAMTS7 AES WDR60 FAM177A1 MINOS1 ANKRD26 DNAL1 MIR205HG COIL C14ORF142 UPF3B C7ORF73 CCDC39 ATP5I SREK1IP1 SPSB2 POLR2I LSMD1 KIAA1377 NPHP1 TRAF3IP1 AGL C1ORF173 CCR10 FAM204A RPP25L CAPN9 IFT27 MRPL53 SS18L2 PPP1R35 SCGB2A1 PPP5D1 ALDH3B2 OFD1 SERF1A BEX5 MRPL36 MORN1 CCDC122 ACVR2B SMIM4 FAM200B CCDC181 ZGLP1 CALML4 ALPK2 C9ORF135 LRRIQ1 S100A7A PFN4 C14ORF37 CCDC154 LRRC6 GPATCH2 CDH23 UPF2 RGS9 KRR1 CHCHD5 IQCA1 C12ORF65 DYDC2 MORN3 CCDC148 ZSWIM7 C9ORF123 CEBPE C12ORF40 MNF1 ICAM4 C22ORF32 CHRNA10 C20ORF201 CHRNA9 EPX ZNF688 C11ORF83 SSPO KIAA1731 RGS13 C11ORF88 CD1E DYX1C1 PTPN20B ZNF683 HTR4 CCDC11 PRR24 C1ORF168 SCG3 CD164L2 CCDC67 DPRX MAK KIAA1407 MORN2 CALY CEACAM4 C1ORF146 MRP63 C11ORF91 METTL10 Top 500 downregulated genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 1 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SRP19 UBL5 BIRC3 GCC2 WFIKKN1 RPL12 SWI5 SLC16A8 IFITM1 RYBP LARP7 TREH USH1C FAU ITM2A USP7 NOL7 H2AFJ GADD45GIP1 MNAT1 XPA OCIAD2 PFDN5 NMB RPL37A ENKUR TNFSF10 UQCR10 IFI27 ARL3 RPS11 RPL27 MAL RPL41 HOPX C9ORF116 GATAD2B SPAG16 COX6A1 RPS15 C9ORF24 CRCT1 DYNLRB2 ATOX1 FAM183A TFF1 MORN5 CRNN AIF1 RPLP1 RPS7 C1QC STMN1 C1QA HMMR MT1F UACA RGS16 ADAMTS2 SLFN11 IFI27L2 SKA1 MRPL51 CCR3 LRRC43 CST7 NTRK1 CLC PRSS57 FCRL6 TRAT1 PLCXD1 HINT1 BAD HINT2 HPGDS BDNF EDN1 FZD8 HIST1H4G SETD1B CD69 RGS1 BARD1 GIMAP7 IL18BP TNFRSF9 CTSW HELLS HCST IGJ CD3D CENPM TNFRSF18 LY86 DNASE1L3 PON1 COX7A1 BEX1 S100A9 PSMB8 APOL6 EFCAB11 RAMP1 JPH3 INHBA ANGPTL4 SP110 HSBP1L1 GDF1 PSME1 PSENEN PSME2 TOX2 CD200 COX17 CYYR1 ATP5J GSTP1 GATA2 NDUFA3 PSMB9 GDPD3 COX7A2 CRIP1 SNRPD2 NDUFA13 C19ORF43 MRPL20 S100A6 NDUFS6 TMEM160 CETN2 C6ORF57 ATP5H NDUFB11 SHFM1 RPL35 NDUFB7 PSMB4 NDUFA2 KRTCAP2 ROMO1 NDUFC1 LIMD2 COX6B1 MYEOV2 NDUFA6 MBLAC1 EDF1 NDUFA4 CETN3 SUB1 MYLPF USMG5 CDK11A YTHDC1 CHCHD1 C8ORF59 MRPS18C PIN4 ATP5J2 GLOD4 NDUFB10 NDUFA7 SCAND1 TMEM256 COX14 S100A13 MIEN1 CLEC2B ALOX12B C6ORF52 ZNF292 CYP2A13 HMGN5 PROC SERTAD1 TMEM258 ANP32A DPM3 APOM SNRPG LAMTOR2 EMC4 MSRB2 CIB1 C19ORF70 C7ORF55 MRPL27 MRPS33 PFDN2 RNASEH2A PTTG1 ZNHIT1 IMMP1L LSM7 UQCRQ SSR4 SSB RPAP3 CMC1 UQCRH HOXB7 FAM60A ERH CBX1 HEBP2 HSPE1 RPL29 RPL34 MORC4 ARGLU1 TTC32 CNFN CLHC1 WFDC3 HNRNPA0 MNS1 C15ORF65 C17ORF50 MMP9 ATP5E MEIG1 CTDP1 RPA3 TCTEX1D2 SLIRP STAP2 SUSD3 S100A8 RIIAD1 CCDC153 FAM161A GCHFR SNX20 SSNA1 TMEM40 VMO1 TESC NUDT1 FNBP4 CD1B PSIP1 SEC62 IFT74 ZRANB2 TMEM107 FAM103A1 CCDC173 XRCC4 PNISR RSF1 CEACAM1 DUSP4 FMR1 ENO2 U2AF1 SERF2 MYL6 NDUFB4 TAF10 UQCR11 TCEB2 CDKN1B COX6C GNLY LTB LAIR2 LPAR6 DAPK2 HIST2H2BF FAM101B TCEAL2 GZMH PMFBP1 CCDC34 GFI1B ANAPC11 PFDN4 GTF2H5 PET100 TRAPPC5 CLECL1 CARD16 NDUFB1 FKBP2 ZIK1 ZNRD1 COX20 COX19 AURKAIP1 CMTM7 BUD31 C19ORF53 C11ORF58 CSRP2 MRPL52 TSPAN1 RBBP6 USP16 WBP4 TEX9 MRPL33 CWC15 NOXO1 SMIM5 PIM2 EPC1 SREK1 CST6 BFSP2 PLEKHF1 OXT PIH1D3 BMX SPINK7 SYCE3 PRSS21 ZBTB18 FXYD3 KRAS SMC4 PDGFB AK9 ARHGEF38 FIS1 FAM133B POLR2F SESN3 EMC6 RSBN1L HYPK EXOC3L4 CLEC2D LTBP1 DNAH9 FFAR3 TTC36 PON3 SCGB1D4 DGUOK HOXB4 GPX7 MT1G COX7B NDUFS5 PNKD MRPL23 JOSD2 PALMD DYNLRB1 POLR2L BCL7C RTF1 SSBP1 TOMM7 TNIK C6ORF222 MRPL41 DPCD DNLZ H2AFV MRPS21 LY6D CLEC11A MYRF ZCCHC14 C1ORF131 NAA38 ECI1 MAGIX CCDC167 RPL39L MRPL21 CCDC174 PAFAH1B3 SNRPF ATPIF1 LSM5 PRRG4 NAA16 MED19 CCDC171 PDCD5 COA6 SYNJ2BP-COX16 LRRCC1 SPA17 C1RL SLC7A2 DDX6 EAF1 PHPT1 C1ORF35 C7ORF57 CCDC146 ADAMTS7 AES WDR60 FAM177A1 MINOS1 ANKRD26 DNAL1 MIR205HG COIL C14ORF142 UPF3B C7ORF73 CCDC39 ATP5I SREK1IP1 SPSB2 POLR2I LSMD1 KIAA1377 NPHP1 TRAF3IP1 AGL C1ORF173 CCR10 FAM204A RPP25L CAPN9 IFT27 MRPL53 SS18L2 PPP1R35 SCGB2A1 PPP5D1 ALDH3B2 OFD1 SERF1A BEX5 MRPL36 MORN1 CCDC122 ACVR2B SMIM4 FAM200B CCDC181 ZGLP1 CALML4 ALPK2 C9ORF135 LRRIQ1 S100A7A PFN4 C14ORF37 CCDC154 LRRC6 GPATCH2 CDH23 UPF2 RGS9 KRR1 CHCHD5 IQCA1 C12ORF65 DYDC2 MORN3 CCDC148 ZSWIM7 C9ORF123 CEBPE C12ORF40 MNF1 ICAM4 C22ORF32 CHRNA10 C20ORF201 CHRNA9 EPX ZNF688 C11ORF83 SSPO KIAA1731 RGS13 C11ORF88 CD1E DYX1C1 PTPN20B ZNF683 HTR4 CCDC11 PRR24 C1ORF168 SCG3 CD164L2 CCDC67 DPRX MAK KIAA1407 MORN2 CALY CEACAM4 C1ORF146 MRP63 C11ORF91 METTL10 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 F2RL1 FOXRED2 EMC1 UHRF1 IDE LOX ERGIC1 CAPN2 CDH17 DDX58 COPB1 RIPK1 CYP2J2 CUL1 ADAM9 ACSL3 FAR2 PIGO OAS1 GGCX STAT1 TRIM25 TSPAN8 SFN EIF2AK2 IL22RA1 CLCA1 OASL STOM ISG15 VSIG4 THTPA UBQLN2 MX1 SIPA1L1 PCMTD2 KDR METTL7A SLC33A1 FZD5 ACO1 CDK5RAP1 SERPING1 BPIFB1 CEACAM6 KRT5 CP KRT7 PIGR ASS1 TM4SF1 KRT4 KRT17 SLC40A1 TTC39A RPS15A AQP5 UPK1B FMO3 ZNF564 FREM2 TNS4 PLCE1 APOBEC3A SCIN SEMA3A CLCA2 RGL1 CD300E GPRC5A CEACAM5 CCL8 AGR2 SLC25A23 GABRP TMEM184B OGDH UNC93B1 PARP10 TOR1B APOL2 ABCC3 ZNF100 VSIG10L ME1 CYFIP1 FKBP9 SLC16A1 KCTD3 FRRS1 IFI44 TMTC1 TDRD9 BUB1 CLEC1B EPSTI1 SAPCD2 SPRY2 TMEM45A C2 DPYD CDC20 CLEC12B ARNTL2 SCD UPK3B NAP1L2 BMPR1A SLC2A6 WDR72 SERHL2 MPEG1 CTSG RHOV EPN3 FGFBP1 MLPH FAM84B ANXA8 KRT14 TSKU SPDEF MCCC2 RHOU PRICKLE1 ALPL WNT5A MAP2K6 FZD9 HELZ2 SLFN13 RSAD2 OAS3 IRF7 FANCI PLA1A TLR1 FAM83D KNTC1 CHIT1 ECT2 GP2 IFIT1 TRAIP CCNF IRG1 GSTA5 IFIT3 OAS2 C3 XAF1 COCH GINS1 DHX58 USP18 CMPK2 IFIT2 IFI16 PCDH20 PREP HERC6 IFIH1 STAT2 PML TINAGL1 ADAR PARP9 HSH2D MUC5B PTGES SERPINA3 LIPG TRIM6 SAMHD1 TLR3 HCN1 SLC6A15 ACER2 BMPR2 EPAS1 TEK TGM2 CDC42EP1 CTGF NPNT SFTPA1 ADAMTS15 SCGB1A1 IFI44L CCKAR HIPK3 FAM107A CYP2B6 SERPINB6 GNS NRP1 SLC25A25 NOS2 NCKIPSD TRIM22 FUT2 COL20A1 PLA2G4C RADIL MUC1 STC1 ADRA2A MAGT1 SEC61A1 EPDR1 DNER SLC25A15 UGT8 GNG12 PNPT1 SEC24B LRP11 ATP2C1 SLCO2A1 NCOA4 ZMAT3 XPR1 CADPS2 TNFRSF19 TMEM47 ANKRD45 SAMD4A SRXN1 MCU IP6K3 CSE1L PCNXL3 LRRN4 FAM189A1 ATP10B AVIL SLFN5 ZC3HAV1 SPPL2A TRIM5 TDRD7 TRIM14 ANKFY1 SLC16A12 FAIM3 SLC6A4 ZNF28 IFI6 FAM171A1 DDX60 C9ORF91 STARD4 CAB39 MX2 IFIT5 HERC5 SLC47A1 PAQR8 GJB2 PAPSS2 DIS3L KRT16 GFPT1 HES4 CDK17 ZNF426 COPG1 SEC31A NCEH1 TMEM62 C1S IFNA14 DYSF ARMCX1 KRT6B OSGIN1 ITLN1 FADS2 OLFM1 LAMA3 KRT6C SPOCD1 KRT6A ANO1 KRT24 C6ORF10 NR2E1 ABO SLC6A14 RHBDL3 TYRO3 GLE1 SIGLEC14 NPC1 TXNDC5 EXOC2 PI4K2B SEC23IP WDPCP TBCCD1 CITED2 SLC46A2 CHST4 POLH ATP8B1 HIRA SLC10A7 REC8 NT5C2 STT3B SUSD2 SLC39A8 PLA2G4A GREM1 GAL BTBD9 ATP13A1 MAP4 SLC38A5 CTPS1 VPS54 SGPL1 PRSS8 TNFRSF11A GCLC ZNF699 CHDH MUC2 NUP160 GANC KDM3A AZGP1 CALN1 USP28 C9ORF152 TXNRD1 RDH11 GSR SLCO1A2 SLC19A1 LRRC59 TEX29 OR1K1 FPR3 RABGAP1 PLD1 FANCC TTI1 VCPIP1 ZNF227 ULBP2 IL17RC TRIM35 CYP2U1 GJB1 SLC15A4 OR52H1 ACSS2 NHEJ1 APBA2 CREB3L1 ALDH1A2 NUP205 GEMIN4 TOP3B SLC11A2 GPC4 SEC24D MID1 SFXN2 MFSD2A TMEM135 ACVR1 VANGL2 KLHL13 PADI3 FAM198B LPCAT3 HSPA13 GPD1L CNP ATRN PHLPP2 USP38 OPHN1 INTS7 PPFIBP2 DLG1 PPIL2 FBXO38 ZSCAN20 GPR161 TBC1D16 ATL3 SNTB1 SLC25A51 TMEM117 RBBP9 SLC41A2 ZDHHC9 SND1 MBTPS2 HEATR5A DNAJC1 GAN GFRA3 SLIT3 BPIFB2 RBP1 FBXW8 BLOC1S3 SLC35G1 ALDH18A1 KIAA0196 PDP2 SLC17A5 LYPD6B POLR1B IPO11 CLEC16A MED17 GPR180 CCDC87 GPR126 SLC44A1 LRP12 FTSJD1 LMBR1 FUT10 MTMR4 C2CD5 SERTM1 PARK2 THSD4 RCBTB1 GABBR2 ACSS3 SNX27 MTPAP SLC5A7 ELMO2 KIAA1429 MUC12 PLEKHM3 ZNF619 SLC52A1 PCDHGB4 GYG2 PTPRG ZNF846 ZNF586 IL20RA FTSJD2 CHRNA3 TMEM231 FREM1 SCNN1G ANKRD36 EVC ST6GALNAC3 ST6GALNAC3 ZKSCAN7 PLA2G3 ZBTB26 ZNF354C C17ORF51 EVC2 SLC4A11 C16ORF89 LRRC16A TMEM255A ABHD6 PARP15 EXD2 PPAPDC2 MARCH6 PRR18 OR52B6 HIATL1 CA5B C8ORF42 UEVLD C16ORF3 ZNF417 GENE-N GENE-ORF1AB C10ORF76 TAS1R1 SS18 LEPREL1 UPK3BL CT62 CAPN13 ERV3-1 EMID1 TANGO6 C6ORF15 SYT14 DBC1 FAM177B ZNF541 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 2 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 CD79B UBL5 RPS27A GCC2 WFIKKN1 RPL12 VPREB3 UBXN1 TPRN PMEPA1 RYBP H3F3A UBA52 TREH CSNK2A2 NT5C FAU CD8B PPIG CD8A ICAM3 USP7 NAP1L1 H2AFJ SAT2 GADD45GIP1 NDUFB6 RPS20 PFDN5 RPS17 RPL37A RPL21 UQCR10 RPS11 RPL14 RPL27 RPL41 TPT1 METTL23 RPL6 RPL37 HOPX C9ORF116 RPL38 RPS3A RPL30 RPL23 RPL13A COX6A1 RPL24 RPS25 C9ORF24 CRCT1 ATOX1 MORN5 RPL19 CRNN RPS29 RPL7A AIF1 RPLP1 RPL11 RPS14 RPS7 C1QC C1QA HBEGF TBC1D10C ITPKB SULT1A1 MT1F MZB1 RNASE1 CAPNS1 RGS16 SLFN11 IGLL5 IFI27L2 MRPL51 CD247 CST7 MATK NTRK1 CLC KLF2 PRSS57 FCRL6 HINT1 KLF13 HINT2 HPGDS EDN1 MAF JAG1 HIST1H4G FBRS LFNG SETD1B LAT GPR65 CD69 PSTPIP1 CD3G SEPT1 RAB37 GIMAP7 CTSW CD27 HCST LCK CD3D PTPRCAP CORO1A CENPM TNFRSF18 CD2 LY86 DNASE1L3 UBASH3A FABP4 COX7A1 CCL24 BEX1 FOLR2 CD19 RAMP1 INHBA APOC2 GDF1 DBP PCBP2 PSENEN TOX2 PLTP COX17 GATA2 NDUFA3 GDPD3 AGER RPS23 RPS19 SFTPC S100A4 COX7A2 CRIP1 RPL10A SNRPD2 RPL22 C19ORF43 MRPL20 S100A6 NDUFS6 TMEM160 CCNI CETN2 ATP5H NDUFB11 SHFM1 RPL35 NDUFB7 RPL18A FAM189A2 NDUFA2 SOD1 KRTCAP2 ROMO1 TRMT112 NDUFC1 LIMD2 MXD4 COX6B1 MYEOV2 FEZ2 NDUFA6 MBLAC1 EDF1 NDUFA4 MYLPF USMG5 YTHDC1 USHBP1 CHCHD1 FXYD1 C8ORF59 PIN4 ATP5J2 GLOD4 NDUFA7 SCAND1 TMEM256 COX14 HIGD2A S100A13 MIEN1 CCDC85B C1ORF54 LST1 LTA PI16 SELM PNLDC1 ALOX12B C6ORF52 TESPA1 CYP2A13 PROC TMEM258 ANP32A DPM3 APOM SNRPG LAMTOR2 EMC4 MSRB2 C7ORF55 PFDN2 NKAP DDX18 ZNHIT1 LSM7 PPP1R18 UQCRQ SSR4 ATP5L HOXB7 C15ORF61 HEBP2 RPL32 RPL29 SF3B5 RPL34 MORC4 CNFN WFDC3 HNRNPA0 MNS1 MMP9 ATP5E RWDD4 MEIG1 CTDP1 RPA3 TCTEX1D2 BCL2L12 SLIRP SUSD3 CELF3 S100A8 TNNT3 PIGZ TSPAN32 GCHFR FCRLA SNX20 SSNA1 GPR18 TPGS1 SPIB TMEM40 TNN FCAMR TESC PVRIG CD1B ALKBH6 SEC62 KCTD12 TMEM107 YY1 FAM103A1 CCDC173 XRCC4 BOD1L1 RSF1 C9ORF43 CEACAM1 RBM34 SNX12 ENO2 SERF2 MYL6 NDUFB4 TAF10 UQCR11 TCEB2 COX6C SNRPB2 LTB LAIR2 MS4A1 FAM101B MMP24 GZMH SFTA2 CCDC34 TNFRSF25 BDKRB2 ANAPC11 GTF2H5 PET100 TRAPPC5 RGS19 NDUFB1 FKBP2 MAPKAPK2 ZNRD1 COX19 SNRNP27 DENND2A AURKAIP1 CMTM7 C19ORF53 GGCT CA6 MRPL52 C19ORF24 CEP63 RBBP6 WBP4 TEX9 MRPL33 CWC15 THOC7 HOXB6 METRN PIM2 YPEL3 RTN3 PPDPF NDUFA11 SIVA1 USF2 PLEKHF1 OXT ACTN3 BMX SPINK7 PDGFB THUMPD2 FIS1 BIK POLR2F BLK IGFLR1 SCN9A NOTCH4 CD79A EMC6 RSBN1L HYPK CD300LB TNFRSF13B FLT3LG GPR82 S1PR4 CLEC2D LTBP1 TTC36 PON3 SCGB1D4 GCSAM DGUOK BIRC7 CDK12 TCL1A PLCG1 MT1G NDUFS5 AK1 MRPL23 JOSD2 PALMD DYNLRB1 RNASEH2C POLR2L BCL7C RTF1 TOMM7 PXMP2 PAGR1 MRPL41 DNLZ H2AFV MRPS21 TMEM99 CLEC11A ZCCHC14 ALKBH7 NAA38 ECI1 MAGIX NSMCE1 NME3 CCDC167 TIMM17B MRPL21 ATPIF1 C17ORF49 LSM5 LPAR5 ZNF585A TMEM134 MED19 FRG1 COA6 C1RL FCRL1 ZNF92 TCTE3 EAF1 PDLIM7 PHPT1 C1ORF35 LSM10 C7ORF57 RSBN1 COL5A3 AES FAM177A1 MINOS1 ANKRD26 MARCH9 FAM213B PTPMT1 UPF3B SDHAF1 PSMG3 C7ORF73 FAM89B ATP5I SREK1IP1 SPSB2 POLR2I LSMD1 CCDC12 MRPS17 CCR10 RPP25L CAPN9 NENF MRPL53 PPP1R35 SCGB2A1 PPP5D1 ALDH3B2 OFD1 SCML4 MORN1 CCDC122 PAK3 SMIM4 FAM200B ZGLP1 CALML4 ALPK2 C9ORF135 CIR1 PFN4 C14ORF37 CCDC154 LRRC6 CDH23 POLR1D KRR1 SLC24A1 CHCHD5 IQCA1 C12ORF65 SLC4A10 ZSWIM7 C9ORF123 TMIGD2 C6ORF1 C12ORF40 MNF1 ICAM4 C22ORF32 C20ORF201 C19ORF60 EPX SIRPG ZNF688 C11ORF83 SIGLEC6 MAMU-DRB1 CLEC17A SSPO RGS13 C11ORF88 DYX1C1 ZNF683 CD164L2 CALY CEACAM4 RHOXF2B C9ORF142 MAMU-DQB1 MRP63 FAM184B CALHM3 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 FOXRED2 UHRF1 SARS2 RBL1 DPP4 MALL DNAJC11 DDX58 PTCRA CACNA1D CYP2J2 NPC1L1 JAK2 SERPINE1 OAS1 PKLR GGCX SLC27A4 CTSD UBQLNL STAT1 TRIM25 EIF2AK2 IL22RA1 CLCA1 APOBEC3G OASL NUP88 CRTC3 MOV10 ISG15 VSIG4 LNPEP FRMD8 MX1 ERC1 TM7SF3 CDK5RAP1 TMEM86A BPIFB1 ITGA2 KRT7 ASS1 TM4SF1 IFI27 KRT4 KRT17 RPS15A AQP5 UPK1B FOPNL CCNO APOBEC3A CLCA2 RGL1 GPRC5A CEACAM5 CCL8 GABRP TMEM109 TMEM184B IFFO1 UNC93B1 ARID5A RMDN3 PARP10 LGALS3BP TOR1B APOL1 MYADM TYMP APOL2 ITGA5 GRN ABCC3 FLVCR2 PYCR1 TOP2A ZNF100 PLEKHN1 ZWINT CCNB2 SHCBP1 TMEM106A IFI44 RNASE2 FLT3 DEPDC1B CDCA5 LHFPL2 TMTC1 BUB1B OPN3 DLGAP5 BUB1 RRM2 CDK1 CLEC1B POLQ KIFC1 EPSTI1 SAPCD2 H1F0 UAP1L1 SPRY2 C2 CCR2 BRCA2 ANLN NCAPH DPYD CDC20 PKMYT1 ANKLE1 TRIP13 CLEC12B TTK MKI67 DTL SCD RNASE3 UPK3B PTPRS EPHB1 SLC2A6 MARS SLC24A4 MPEG1 SLC2A8 CTSG FGFBP1 MLPH WNT5A ELP3 IPO9 MAP2K6 FCN1 HELZ2 C11ORF82 ARHGAP11A RSAD2 OAS3 IRF7 EME1 FANCI ZBP1 TCF19 PLA1A C17ORF53 TLR1 HIST1H3D KNTC1 PIK3R5 GZMA CHIT1 ECT2 TACC3 MCM5 PBK IFIT1 RACGAP1 MELK TRAIP CCNF NCAPG2 FCHO1 CCR5 NEIL3 RAD51AP1 GSTA5 IFIT3 CDT1 ZRANB3 OAS2 C3 SIGLEC1 XAF1 COCH CA7 DHX58 CHAF1A USP18 CMPK2 IFIT2 IFI16 XRCC3 DHFR HERC6 IFIH1 STAT2 PML TINAGL1 MCOLN2 PARP9 PARP12 HPSE SLC39A14 TRIM6 TRAFD1 SAMHD1 HCN1 SLC35F3 ACER2 BMPR2 SEPT4 LY6E IGFBP4 ADAMTS15 IFI44L PRX PLXDC2 GIMAP4 ZNF692 THEMIS2 NRP1 SLC25A25 PLCL1 PRSS36 RAB30 NCKIPSD TRIM22 GPRIN3 KCNN2 COL20A1 PLA2G4C MUC1 ADRA2A DUSP6 SEC61A1 PRPF3 DHRS2 CDC25B SLCO2A1 E2F7 C15ORF52 SAMD4A RIPK3 IP6K3 PCNXL3 LRRN4 FAM189A1 ADRB3 SLFN5 MB21D1 MARS2 SPPL2A TRIM5 TRIM14 ANKFY1 SLC16A12 PACSIN1 FAIM3 SLC6A4 CCDC15 AARS IFI6 C17ORF47 FAM171A1 DRD1 FAM111B DDX60 WDHD1 C9ORF91 APOBEC3B TTC31 C19ORF66 MX2 IFIT5 HERC5 METTL4 ZNF573 SLC47A1 PAQR8 GJB2 KLHDC7B SMCHD1 TMEM62 BTN3A1 MOB3C PANX1 AZU1 PRKCH ADAM10 FLRT2 KRT6B ITLN1 FADS2 DNM1 SDC3 CXCL14 KRT6C KRT6A CDC20B C6ORF10 SCN5A FANCA PPM1J IRAK1 KRBOX1 SIGLEC14 NPC1 ADPGK EXOC2 IFITM10 LDHC PI4K2B WIPI1 SEC23IP ZNF34 CITED2 CNPPD1 CLN6 SLC46A2 EFTUD1 SUV39H1 MCM9 REC8 NT5C2 TMEM123 SLC39A8 PLA2G4A HECTD3 MYEOV BTBD9 ATP13A1 MFSD12 TRPC4AP MAP4 SLC38A5 CTPS1 PELO PDGFRB VSIG2 TNFRSF11A PDE3B KLF8 CDH15 CHDH MUC2 NUP160 GANC ZNF3 FER1L5 HLCS SLCO1A2 DISC1 FPR3 ATP13A2 UBIAD1 FANCC ZSCAN32 HPS3 ULBP2 PTGIR AP3M2 CYP2U1 GJB1 ACSS2 LIMK1 CREB3L1 MCM3 ALDH1A2 NUP205 POLD1 POC1A TOP3B SEC24D HMG20A CENPT HES6 HHIPL1 TMEM135 SLC44A5 VANGL2 RAB15 VGLL3 LY6D LPCAT3 GFRA1 GPD1L CNP RFC3 MYO5A SNX18 PPFIBP2 LMF2 PPIL2 CLPB PANK3 PADI1 DCLRE1C ATP11A TTC39C SLC41A2 HIST1H3F DOCK10 GIMAP6 DNAJC1 GAN PLK4 MGAT5 CENPJ HYLS1 MATN1 NGFR COL15A1 BPIFB2 RBP1 BLOC1S3 SLC35G1 PDXP ALDH18A1 ERP27 ZXDC ITPR2 LDLRAD3 SUSD1 C16ORF95 FTSJ3 SEPT6 ADCK1 PUS1 POLR1B TOP3A SOGA2 FTSJD1 SPIN3 FANCB ELMO1 MIIP C1QL3 KCNA3 ARSJ OXNAD1 FOXN4 GABRB1 SNX27 RUSC1 MTPAP SLC5A7 RBM44 UBE3D VPS33B TTC24 PLEKHD1 MUC12 MVB12B PCDHGA6 DACT3 SHISA8 LSM11 DCLK2 CHST12 DLEU7 GYG2 ZNF846 FTSJD2 C20ORF118 CHRNA1 PHF17 ANKRD36 EVC C14ORF159 TM4SF19 PTPN9 ADAMTSL5 ST6GALNAC3 ST6GALNAC3 JAM3 CCHCR1 CSTF2T KIAA0391 AMZ1 SAP130 EVC2 MTL5 C16ORF89 CDC23 TMEM255A PARP15 APOBEC3H DNASE2B EXD2 CCDC36 OR52B6 CDYL2 SLC24A6 C16ORF3 GENE-N C10ORF76 TAS1R1 C14ORF182 UPK3BL MCIN ALPP PSG3 PRR4 CATSPER4 ERV3-1 C6ORF15 ZNF541 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 4 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 RPS27A GCC2 NINL UBD MAP1LC3A RPL12 SLC6A20 UBXN6 BAIAP2L1 ACE2 IL17RD PRR15L TPRN HSPB1 USP2 CALM1 SULT1B1 TST TREH AGT BAG6 FAU ITM2A NAT14 PKIG CNTD1 CISD1 OCIAD2 PFDN5 NBEA ENKUR TMC5 RPL21 TFF3 OSBPL6 STOX1 FAM229B C20ORF85 CEBPD ARL3 ALMS1 MUC15 PPIL6 MT1E C9ORF116 MAP3K19 PBX1 TOX3 NFIB SPAG16 RPS3A HUNK RPL23 COX6A1 RPL24 USP51 WDR38 C9ORF24 CRCT1 DYNLRB2 MAPK10 FAM183A MORN5 FOXQ1 ACOT13 ANK3 TMIGD3 RPL7A MAP7 WDR78 RPLP1 ZNF462 AKAP14 RPS7 ENPP4 RHOB SRD5A1 SULT1A1 MT1F UACA TIMP4 CES1 SLFN11 IFI27L2 C5ORF30 LRRC43 CRIP2 MLF1 TMEM182 PDZD4 NCALD PRSS57 HINT1 BAD BMP4 CLDN3 ANKRD6 FGF12 CBLN4 WNT5B SORCS1 CCDC170 PTPRU ST6GALNAC2 CASZ1 QPRT CFB TNFRSF9 LY86 DNASE1L3 PON1 COX7A1 CCL24 S100A9 TXLNB CYP2E1 FOLR2 EFCAB11 RAMP1 RHCG GDF1 SVOPL PSENEN SHANK3 PLTP CYYR1 TPPP3 GSTP1 NDUFA3 FBXO16 S100A4 CRIP1 S100A6 GSTA3 CCNI CETN2 RPL35 FAM189A2 SOD1 NDUFC1 MYEOV2 DSTN MYLK MBLAC1 CETN3 MYLPF USMG5 GLOD4 NDUFA7 SCAND1 TMEM256 HIGD2A S100A13 MIEN1 GJB7 RSPH10B CAPSL LCA5L SELM SLC5A10 TAGLN3 ALOX12B GPR111 C6ORF52 RSPH4A CYP2A13 PROC BAMBI ZSWIM6 TMEM258 DPY30 DPM3 EMC4 MSRB2 CIB1 MIF IMMP1L RPAP3 CMC1 FAM60A SCG5 RPL34 CHST6 CNFN CLHC1 WFDC3 MNS1 C15ORF65 PIR MMP9 ATP5E MEIG1 ODF3B MRPL47 ATP5G2 TCTEX1D2 PSD3 S100A8 GCA RIIAD1 CCDC153 FAM161A CLDN8 PIGZ TMEM212 LRRC23 GCHFR SPNS3 TNFAIP8L1 TPGS1 TMEM40 VMO1 FCAMR VNN1 SLC51A CLGN AGR3 CD1B PSIP1 ARL13B SEC62 IFT74 KIF3B TMEM107 CCDC42B CCDC173 CCDC160 TMEM238 FOXC1 CBR3 CMTM4 SERF2 UQCR11 TCEB2 LAIR2 CACNA2D3 TMEM255B TCEAL2 TMEM95 PIWIL2 MMP24 RSPH1 ECT2L C1ORF87 BEST2 C4A BDKRB2 FCN3 GTF2H5 HLX GNAS NDUFB1 COX19 SYAP1 AIG1 CMTM7 C19ORF53 CSRP2 MPST FFAR2 TSPAN1 DYNC2H1 CEP63 FILIP1 TEX9 MRPL33 NOXO1 METRN FAM174B C10ORF95 PIM2 YPEL3 IFT43 PDGFA CST6 SLC14A2 ADRB1 OXT PIH1D3 STMND1 BMX TGFA CMBL RNF183 SPINK7 ZBBX ZBTB4 FXYD3 FANK1 AK9 TTC26 MSRB3 MBOAT2 FIS1 SESN3 ZNF749 HYPK ABCA5 LTBP1 DNAH9 CYP4X1 TTC36 PON3 IGFALS SCGB1D4 BIRC7 PIH1D2 MT1A PRDX6 KIF9 MT1G NDUFS5 AK1 ACSF2 MRPL23 PALMD DYNLRB1 POLR2L TOMM7 MOK DLC1 CAPS PXMP2 DPCD DNLZ RIBC2 MRPS21 TLL2 KIAA1211L NFIX LCA5 IGF2BP2 CLEC11A EMB MACROD1 ECI1 MAGIX ATPIF1 MYCBP GRIP2 IQCK SPA17 SEMA3D C1RL ACADL SLC7A2 MAPK8IP2 TCTE3 EAF1 C7ORF57 SPAG17 CCDC146 C21ORF59 ELOF1 WDR60 FAM177A1 SNAP23 ANKRD37 DNAL1 MIR205HG UPF3B TNXB FAM47E C11ORF52 CCDC39 C16ORF55 LZTFL1 POLR2I LSMD1 CCDC103 TTC25 KIAA1377 NPHP1 TRAF3IP1 EFCAB2 CCDC176 MED31 HAGHL C1ORF173 FAM154B PCDP1 CGB CAPN9 IFT27 MRPL53 SCGB2A1 WDR66 PPP5D1 ARL16 CCDC125 ALDH3B2 CXXC4 MORN1 CCDC122 FBXO15 SMIM4 FAM200B CCDC181 AK7 RSPH9 LRRC46 ADGB CALML4 NWD1 C9ORF135 LRRIQ1 C7ORF41 PFN4 FBP2 C14ORF37 PACRG CCDC154 LRRC6 CCDC136 ATP5S TCTEX1D4 PPP1R36 KNDC1 ABRA TTLL9 ALS2CR12 SLC6A16 CHCHD5 IQCA1 DYDC2 C8ORF47 CHST5 PAPPA2 ZC2HC1A C5ORF38 IRX2 C2ORF54 MORN3 C7ORF63 FAM221A CCDC148 CCDC33 EFCAB1 C1ORF192 PIFO NME9 C5ORF49 WDR16 WDR96 IQCG FAM81B ZSWIM7 FAM92A1 HDGFRP3 MS4A8B C12ORF40 MNF1 IRX3 C22ORF32 C20ORF201 B9D1 ZNF688 C11ORF83 C2ORF62 SSPO RGS13 C11ORF88 CD1E DYX1C1 C1ORF100 CCDC11 DYDC1 SCG3 CCDC19 CIB3 OR6V1 CD164L2 CCDC67 DPRX LRRC36 MAK CAPS2 KIAA1407 C9ORF9 MORN2 GAS2L2 SMKR1 CA10 SPATS1 CCDC164 SAPCD1 WDR52 ACYP1 DNAJB13 NRG2 C2ORF70 C1ORF141 SPATA17 C10ORF67 CCDC65 C1ORF189 CATSPER3 FAM165B ENKD1 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 MAOA CCL5 TM6SF2 TCF12 TMEM37 CD34 TMPRSS2 ADAMDEC1 MALL KPNA2 AADAC THY1 ICOS DDX58 RBP2 CXCL10 TUBGCP3 PLA2G2D NPC1L1 ACSL3 FAR2 TREM2 OAS1 DMBT1 CYP2C18 TSPAN8 EIF2AK2 PLD3 CLCA1 FYN APOBEC3G ISG15 VSIG4 VSTM2B KALRN MX1 HSD3B2 KDR CDK5RAP1 PARP16 ALDH1A3 CAV1 BPIFB1 CP CXCL1 CXCL6 ITGA2 PPP1R14C KRT7 LMO3 ASS1 TM4SF1 IFI27 KRT4 KRT17 HES1 TTC39A IL33 RPS15A AQP5 UPK1B FMO3 KLK11 FOPNL CCNO ITGA10 APOBEC3A HIST1H2BK SCIN SYTL5 SEMA3A HIST1H2AC CLCA2 RGL1 GPRC5A CEACAM5 CCL8 GSTA1 PLA2G7 AGR2 TPST1 GABRP MPZL2 TOP2A ZNF100 MILR1 NREP SLC16A1 ERI2 NEK2 MGST1 NUF2 IFI44 FLT3 IGFBP2 LHFPL2 TNFRSF17 FH TDRD9 AURKA DLGAP5 BUB1 RRM2 SLC1A3 CDK1 CLEC1B EPSTI1 SAPCD2 HGF ALOX15B CCNB1 IGLL5 ANLN CDC20 TTK ARNTL2 RNASE3 MPP6 UPK3B YPEL1 S1PR5 IGFBP3 SLC2A9 SERPINH1 STAR WDR72 MINPP1 ELANE CTSG LYPD3 FGFBP1 GPR87 ANXA8 KRT14 C1ORF106 CDH3 TPD52L1 SPDEF SFRP4 ALPL WNT2B FRZB WNT5A KRT13 TBC1D8 MAP2K6 UGT2A2 UBE2Q2 SLC24A3 TRPV6 KLRD1 RSAD2 UBE2T OAS3 NKG7 ESCO2 PLA1A C17ORF53 MS4A6A IGJ KNTC1 PIK3R5 GZMA LANCL3 GP2 PBK IFIT1 RACGAP1 MELK TRAIP CCR5 GZMK RAD51AP1 EOMES GPR171 KCNA6 GSTA5 IFIT3 CDT1 ZRANB3 LRP8 OAS2 CD86 C3 SIGLEC1 XAF1 COCH CHAF1A USP18 CMPK2 IFIT2 NTRK2 SEPT3 DHFR HERC6 IFIH1 SFTPB TINAGL1 KCTD19 HPSE C11ORF85 TRIM6 ANGPTL4 MAMDC2 HCN1 EPHA1 SLC35F3 FOS RASGRP3 UNC45B SPARC SMAGP NPNT SFTPA1 SCGB1A1 IFI44L TMEM176B ARRDC3 CHST1 GIMAP4 S100A16 IGFBP7 SERPINB6 NRP1 MARCKSL1 PLCL1 NOS2 LGI4 KCNE4 FUT2 AKR1E2 KCNN2 CYTIP SPDYA COL20A1 RADIL MUC1 ADRA2A GPX3 GALNT7 ALKBH3 UGT8 SMIM6 CDC7 PNPT1 DHRS2 EPHA7 LRP11 HSPA2 SOAT1 ADORA2B E2F7 SLC38A6 ID1 COMP IP6K3 PRRX2 OTX2 SLC35G2 DHRS13 ZCCHC12 SERPINB7 FAM189A1 GMDS PRF1 FAM57A ADRB3 STRA6 AVIL SLFN5 SPPL2A SELL F13A1 SLC16A12 GPR183 DERL3 GIMAP1-GIMAP5 FAIM3 CCDC15 PVRIG IFI6 FAM171A1 C2ORF76 SLC20A1 DDX60 IDH2 CHAC2 MX2 IFIT5 HERC5 SLC47A1 GJB2 PAPSS2 ENTPD4 FLG2 IGFBP1 MDK TMEM62 NMU AZU1 GZMB GNLY FLRT2 HPDL KRT6B FHL2 ITLN1 SV2B SDC3 CXCL14 ITGB6 CDC20B ADAMTS9 C6ORF10 NR2E1 ABO APBB1IP B3GNT6 SLC6A14 RHBDL3 SH2D6 LPO SIGLEC14 LIPE BCR LDHC FBLN1 WIPI1 FBLIM1 SCD5 SLC46A2 CHST4 REC8 PTER ZNF558 SUSD2 SLC39A8 PLA2G4A KLK10 VSIG2 ELF5 ATP6V1G2 FAM3D TNFRSF11A CPM MUC2 ECEL1 STEAP2 USP28 SLC22A3 TMEM254 RNF32 SLCO1A2 SLC9A9 CMKLR1 FPR3 IVD FANCC HPS3 ZBTB25 ZNF225 ZNF45 ULBP2 DIO1 GJB1 BAAT HSD17B13 SLC15A4 CREB3L1 ALDH1A2 ANAPC1 POC1A ST8SIA4 TOP3B TMED3 SFXN2 CENPT HES6 GALNT10 ZP3 DSC3 CPE PADI3 LY6D LPCAT3 LRRC8C UFSP2 CLDND1 TMEM156 CPAMD8 IGFBPL1 SERTAD4 ANKRD13C OPHN1 SNTA1 PPFIBP2 DLG1 ZNF239 PANK3 PADI1 LIN52 SLC25A51 TMEM117 DNAH14 HIGD1A TCTN1 SLC41A2 KIAA1586 DNAJC1 GAN RAB3D PDK3 PLK4 ANKRD29 CENPJ HYLS1 OPA1 NGFR COL15A1 RBP1 BLOC1S3 SLC35G1 DFNA5 MOB3B XPO4 LYPD6B P2RX1 HHATL CCDC87 MKLN1 GPR126 SOGA2 DIRC2 FUT10 PARK2 OXNAD1 FOXN4 MTPAP SLC5A7 RBM44 CERS3 MUC12 SHISA8 DLEU7 RNF39 BAIAP3 PTPRG ZNF846 IL20RA C20ORF118 CHRNA3 HMSD ADARB2 SCNN1G PHF17 TLE6 TM4SF19 ST6GALNAC3 ST6GALNAC3 JAM3 PHYHD1 CDKAL1 SYT5 C17ORF51 KIAA0391 EVC2 SLA2 LAMB4 MTL5 C16ORF89 PLA2G1B C21ORF33 TMEM255A APOBEC3H DNASE2B WDR67 KLRC3 CCDC36 SAMD3 PYHIN1 PTPLAD2 CCKBR CA5B C8ORF42 ZNF485 TAS1R1 SS18 UPK3BL MCIN GAST CNIH2 CRABP1 C8ORF48 TEX33 IRGC C7 CNGA4 CT62 PRR4 ERV3-1 C6ORF15 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 7 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 RPS27A IGSF8 WFIKKN1 HYOU1 UBD RPL12 PFAS KPNB1 SLC6A20 UBXN6 IL1A VPREB3 EPB41L1 ACE2 YWHAG ARRB2 PRRC2B TPRN RYBP FYCO1 FBL BAIAP2L2 GIGYF2 TREH AGT CLIP4 BAG6 ARHGEF11 FAU PABPC1 CD4 DIAPH1 NAT14 ICAM3 USP7 PLEC TLN1 CABLES1 TPSAB1 PFDN5 RPS17 ARL4D RPL21 FRK CGNL1 TPT1 RPS8 RPS3A HUNK RPL23 RPL24 RPSA CRCT1 MAPK10 RPL7A AIF1 RPLP1 SRRT ATP10A ARHGAP30 TNFAIP2 MYO1G C1QC PRKCSH ATG4B HBEGF FLNA DDRGK1 TGFBI QSOX1 GPD1 ARAP1 ITPKB RHOB MRC1 OCRL MT1F TMTC2 PDGFC CAPNS1 MPND ADAMTS2 SLFN11 MMP19 C5ORF30 SH3PXD2B LRRC43 CPA3 TNRC6C MATK PDZD4 COL18A1 ANGPTL6 STAC AVP VPS9D1 CISH FAM83E HPGDS AR CELSR1 TONSL MYH14 ARHGEF16 TCF7L1 CBLN4 FZD8 JAG1 RAP1A SORCS1 SAFB HIST1H4G OR2A5 FZD7 PWWP2B CEBPB SDK2 KDM4B RXRA SETD1B COLEC12 TNRC18 GPR162 QPRT CREG2 IL18BP TNFRSF9 CLEC5A CCDC88B CLEC4A TNFRSF18 LY86 VAV1 FABP4 CCL24 RETN CCL17 CLEC6A CD19 CLEC4E RAMP1 JPH3 INHBA PTPRT HAS1 ARG1 APOC2 ZNF704 GDF1 TOX2 RPL8 YBX1 GATA2 RPS23 RPL3 RPLP0 NGFRAP1 S100A4 CRIP1 GPAM NR1D2 S100A6 CCNI RPL35 BMS1 ATF4 FEZ2 MBLAC1 RPS3 MYLPF USHBP1 GLOD4 NDUFA7 C1ORF54 MFHAS1 LST1 PNLDC1 SLC5A10 TCF23 BEST1 HSPA6 PPP1R15A B3GNT5 C6ORF52 SOCS2 CYP2A13 TLCD2 PABPC3 PROC BCORL1 TMEM213 IRS2 IER5 SERTAD1 CLCF1 ZBTB34 MMP10 SLC29A1 C19ORF10 PHLDA3 PTMA HOXB7 STAG2 RPL32 AMIGO2 NKRF IRX5 MFAP1 KIAA1683 CNFN HIST1H1A CLHC1 WFDC3 HNRNPA0 PURB SPATC1L MMP9 RND1 MVD TMEM121 ANKRD55 CELF3 GCA PIGZ GCHFR SNX20 SSNA1 PTGDS TCAP BATF3 WDR86 TPGS1 SPIB TNN VNN1 GPRASP1 GYPC CNGA3 CD1B MCM7 MBNL3 TRHDE KIF3B KCTD12 ZBED6 CRIM1 ETS2 CEACAM1 RRAGD PTGS1 FOLR3 HNRNPA1 COX6C LAIR2 HRH1 IL17D PPFIA4 CENPV CDC42EP2 PIWIL2 CADPS HPD SLC6A13 PRUNE2 FFAR4 C4A BDKRB2 GTF2H5 APOBR DOK3 IGF1 SIM2 GNAS UBALD2 MAPKAPK2 LDHAL6A DENND2A AIG1 CDC42BPB C6ORF62 C9ORF16 LTB4R USP36 FFAR2 HSD17B1 ALDOC ATXN1 TMEM91 PRSS53 HOXB6 MARCH4 ITPA HDAC5 NOXO1 CHST3 KIRREL3 METRN MBD3 FAM174B C10ORF95 PIM2 CACNA1A RTN3 PPDPF CDR1 KCTD10 AMOTL1 FBXO31 MICAL3 DTX4 GNL1 C6ORF106 TSSC4 ITPR1 HIPK2 PDGFA KPNA4 USF2 OXT ACTN3 STMND1 SYDE2 ZNF81 BMX RREB1 LPP LIN7B ADCY10 TMC1 SPINK7 PRSS21 ZBTB18 ZBTB4 PRSS12 CTTNBP2 FOXP4 TRA2A MSRB3 ADAMTS13 IDO2 CD22 SESN3 FGD4 ZNF75D ENPP1 GPR82 EXOC3L4 MTHFD1L LTBP1 DNAH9 DRD2 TTC36 PON3 MCF2L2 IGFALS FAM151A HOXB4 BIRC7 TEF RPS4X TCL1A MT1G KIAA1161 FOXJ2 GCSAML ZBTB48 ZNF319 CAPS PAGR1 DNLZ MAOB C1ORF159 ZCCHC14 TSHZ1 SVIL SACS ECI1 MAGIX PCF11 TP53I13 SETD1A MIA PPP4R4 GRIP2 ARSD CBX6 JOSD1 SEMA3D RUFY4 PALM3 C1RL SLC7A2 BAZ2A FAM120A CARD9 MAPK8IP2 EAF1 PDLIM7 GOLGA7B MLLT6 AGPAT1 CENPB AES GABPB2 RGL3 FAM213B HMBOX1 PHF1 ANKRD2 GLTSCR2 FBXW4 TNXB CRCP NOB1 TMEM185A POFUT2 SART1 SPSB2 GPR124 LEPREL2 GPR85 C12ORF44 FAM69B KCNN3 ZNF582 TCEANC RAB17 TMEM59L MYBPC2 AZI1 CGB CAPN9 YRDC AMER1 SCGB2A1 ARL16 ALDH3B2 TGFBR3L MORN1 UTP14C LHFPL4 SOGA3 CDK3 ZGLP1 CSAD DCAF4L1 GSG1 ALPK2 HIP1 CCDC154 MAML3 CDH23 ABRA LDLRAP1 SLC6A16 TSSK6 FER1L6 OPRL1 PAPPA2 C2ORF54 FAM211A FUK MNF1 TRIM58 MAMU-DOA C20ORF201 C19ORF60 KCNK12 MAMU-DRB1 SSPO PLEKHG4B RGS13 CD1E PTPN20B SEPT8 HTR4 FCRL4 MYBPH CAPN11 PRR24 AWAT2 C2ORF71 OR6V1 MC3R GAS2L2 RGAG4 CEACAM4 RHOXF2B PROSC CATSPER3 CCNJ ZNF784 LHX4 MOV10L1 VSX1 C11ORF94 TRMT2A ZNF653 FAM69C NRN1L Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UHRF1 CMA1 ADAMDEC1 ERGIC1 EPB41L2 KPNA2 ICOS PTCRA CXCL10 SLC7A7 PLA2G2D PPT1 SEPP1 CUL1 ADAM9 ACSL3 JAK2 IL12B HMOX1 TREM2 OAS1 CTSD GIPC2 TMEM176A PLD3 CD7 FYN APOBEC3G OASL NUP88 SIRPB2 ISG15 VSIG4 CXCL9 MX1 MXRA8 TM7SF3 LRRC61 CDK5RAP1 TMEM86A MGAT1 SERPING1 ASS1 TM4SF1 SLC40A1 RPS15A AQP5 UPK1B KLK11 FOPNL CCNO CD180 APOBEC3A CYBRD1 CLCA2 RGL1 CEACAM5 CCL8 GABRP TOR3A SUMF2 MYADM APOL2 SLAMF8 ITGA5 GRN CPVL PLK1 SLC38A7 TOP2A ZNF100 ZWINT CDCA8 CCNA2 EZH2 CCNB2 SCARB2 CTSB UBE2C CREG1 NREP SLC16A1 NEK2 KCNK13 SHCBP1 ZNF366 TMEM106A NUF2 IFI44 RNASE2 FLT3 DEPDC1B CDCA5 SPAG5 LHFPL2 OPN3 KNSTRN FH AURKA DLGAP5 BUB1 RRM2 CDK1 CLEC1B MAFB ORC1 KIFC1 SAPCD2 HGF UAP1L1 SPRY2 C2 CALCRL CCR2 BRCA2 TPX2 ANLN NCAPH CEP55 CDC20 PKMYT1 ANKLE1 CLEC12B TTK MKI67 KIF20A DTL RNASE3 UPK3B A2M EPHB1 BMP7 SLC2A6 SLC2A9 MYC APLP1 SLC2A5 MPEG1 SLC2A8 B3GNT9 FGFBP1 CDH3 COL1A2 WNT2B LMX1A WNT5A IRF8 ELP3 TNFRSF11B MLLT11 PRC1 RNF26 UBE2Q2 ARHGAP11A GSG2 IL10RA SELPLG NKG7 ESCO2 DENND1C FANCI AOAH TCF19 SLAMF7 PLA1A CCL1 FAM64A CD28 TLR1 CTSW FAM83D PLD4 GFI1 MS4A6A SLC29A3 CD27 LCK IL2RB KNTC1 GZMA TACC3 NUSAP1 MCM5 LPXN PBK IFIT1 BORA FAM26F RACGAP1 ITGB7 MELK TRAIP GPR31 CCR5 GZMK COTL1 NEIL3 EOMES GPR171 GSTA5 CDT1 OAS2 CD86 C3 SIGLEC1 COCH GINS1 GPR141 COL3A1 PREP SNX22 RASA4 MCOLN2 HPSE SLC39A14 TRAFD1 SAMHD1 C5AR1 MAMDC2 SEPT4 IGFBP4 RASGRP3 CTSH IFI44L SERPINB9 TMEM176B GIMAP8 ARRDC3 FUCA1 CSF1R GIMAP4 PDPN IGFBP7 THEMIS2 NRP1 MARCKSL1 CYP2S1 PLCL1 IL16 RAB30 NCKIPSD FUT2 KCNN2 CYTIP DUSP6 RRM1 PGAM1 SMIM6 MFSD5 TNFRSF21 LRP11 ATP2C1 SOAT1 NCOA4 ZMAT3 E2F7 SLC38A6 APOBEC3C MN1 RIPK3 IP6K3 OTX2 LRRN4 ZNF671 APBA3 PRF1 NAGPA ADRB3 DNASE2 AVIL SLFN5 MB21D1 F13A1 RASD1 SLC16A12 GPR183 NCKAP1L DERL3 FES GIMAP1-GIMAP5 FAIM3 SLC6A4 CCDC15 BIN2 CXCL11 IFI6 FAM111B IDH2 EOGT C9ORF91 PRPS2 MX2 IFIT5 HERC5 SLC47A1 PAQR8 GJB2 ACOT7 IGFBP1 REEP4 GLUD1 RAB8B AZU1 RAP2B CCR7 PRKCH GZMB GNLY ADAM10 P2RY6 KLHDC8B OLFML3 CD70 SDC3 CXCL14 KRT6C KRT6A CDC20B C6ORF10 NR2E1 CGA PPM1J SH2D6 CECR1 IL21R UBE2J1 KRBOX1 APOBEC3F SIGLEC14 NAAA TNFRSF1B ARRB1 TXNDC5 ADPGK EXOC2 LDHC WIPI1 SLC35A4 SEC23IP NNT TBCCD1 CMTM3 CLN6 SLC46A2 SLC25A10 CHST4 ST3GAL5 REC8 STT3B SLC39A8 HAPLN3 MFSD12 LILRA1 TPP1 SYN1 SLC38A5 ACP2 CTPS1 PELO NLRP2 SGPL1 GSDMA TNFRSF11A NLRP3 ZNF699 CPM KLF8 ABI3 MEGF9 FBXO43 TPBGL CMKLR1 FPR3 UBIAD1 KCNA5 ULBP2 GIMAP1 HAVCR2 PTGIR GIT2 NR1H3 ABCA6 SLC15A4 SGPP1 MCM3 KCNIP3 POC1A AKR7A2 CRTAP DSE HIBADH TMEM51 MFSD1 DDX20 KCTD5 SEC24D SFXN2 CENPT HES6 RPA1 ZP3 GNA15 VANGL2 PADI3 LY6D FAM198B LPCAT3 NHLRC3 CNP CDR2 SNX18 CDC42SE2 PPFIBP2 APEH YIF1B CREB3L2 PANK3 TMEM117 TTC39C PCTP GIMAP6 GRAP MPI DNAJC1 P2RX7 GAN PLK4 HYLS1 COL15A1 RBP1 BLOC1S3 ALDH18A1 ERP27 MOB3B PALD1 LDLRAD3 GPR146 TPCN2 ADCK1 CPOX MPP1 P2RX1 PRKCQ TNFAIP8L3 CCDC87 SLC44A1 SOGA2 RNF144B UBAC2 FBXO30 ELMO1 HTR7 TMEM206 SLC43A1 FOXN4 SNX27 MTPAP SLC5A7 TTC24 MUC12 CHST12 DLEU7 TOMM40L FIBCD1 CHRNA3 MOXD1 TM4SF19 JAM3 IL12RB2 KIAA0391 KCNJ1 ARHGAP22 EVC2 SLA2 MTL5 C16ORF89 CDC23 C21ORF33 TMEM255A APOBEC3H DNASE2B C1ORF85 CCDC36 CYBASC3 HIATL1 SIRPG CCKBR CA5B CDYL2 TIGIT MARCH1 SLC24A6 STARD8 SS18 LRRC33 UPK3BL MCIN GAST ERV3-1 C6ORF15 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 10 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 GCC2 NINL WFIKKN1 BAIAP2L1 ACE2 IL17RD MIPOL1 TPRN ST14 USP2 QSOX2 TREH AGT ERBB2 BAG6 ANKRD66 AKAP9 FBP1 NAT14 PKIG NEO1 ELL3 XPA RASEF NBEA ENKUR TMC5 OSBPL6 MCF2L STOX1 SRGAP1 FAM229B IL5RA ARL3 ALMS1 MUC15 SCGB3A1 MT1E NEK10 KIF21A C9ORF116 NME5 PTPN13 MAP3K19 LMO7 C6ORF132 PBX1 TOX3 NFIB SPAG16 RASSF6 HUNK USP51 C9ORF24 MUC16 CRCT1 DYNLRB2 MAPK10 TJP1 FAM183A TFF1 MORN5 TMPRSS11B SORBS2 C2ORF73 ANK3 TACC2 DCDC1 CHST9 FMO2 WDR78 ENPP4 RHOB MACC1 MT1F UACA CES1 IFI27L2 B4GALNT3 LRRC43 CA11 ITGB8 PDZD4 FAM83H DZANK1 FAM83E EDN1 CELSR1 KIAA1522 JAG2 CAMSAP3 MYH14 CLDN3 MST1R ARHGEF16 EPS8L1 NAV2 BMP3 FGF12 JAG1 SORCS1 CCDC170 MAB21L1 HIST1H4G PTPRU PWWP2B TNK2 CASZ1 CCL24 TXLNB EFCAB11 CLEC4E DCDC5 RAMP1 SLC4A5 GDF1 SHANK3 TPPP3 FBXO16 GSTA3 CETN2 RBMS3 FAM189A2 PLEKHG2 FHAD1 MYLK MBLAC1 USHBP1 GLOD4 SCAND1 S100A13 EDAR GJB7 RBM11 RGS22 RSPH10B LCA5L SELM PNLDC1 SLC5A10 TAGLN3 ALOX12B DNAH1 GPR111 ESRRG C6ORF52 RSPH4A EDNRA COL21A1 TMEM52 CYP2A13 HMGN5 PROC CIB1 DLG2 RPAP3 FAM60A IRX5 GP1BB CNFN CLHC1 WFDC3 MNS1 C15ORF65 PIR LHB MT1H MEIG1 CTDP1 ODF3B TCTEX1D2 PSD3 STAP2 CELF3 RIIAD1 CCDC153 CCDC78 FAM161A WDR90 LRRC23 GCHFR SPNS3 PTGDS WDR86 TPGS1 TMEM40 TNN MSI1 RP1 GPRASP1 SLC51A GOLGA6A AGR3 CD1B KIAA1211 ARL13B PLEKHA6 SEC62 IFT74 KIF3B GLIS3 CCDC42B KIF1A PPP1R9A IGF1R LAMC2 CCDC173 CEP290 FOXC1 CEACAM1 CTNNAL1 GRAMD1C CBR3 BTC ENO2 CMTM4 LAIR2 CACNA2D3 TCEAL2 PIWIL2 RSPH1 C1ORF87 MEGF10 CCDC34 C4A BDKRB2 ZDHHC11 HLX COX19 ANKRD18A AIG1 TSPAN1 DYNC2H1 FILIP1 TEX9 IFT81 SCNN1D HOXB6 MARCH4 NOXO1 SYNE2 KIRREL3 KCTD15 METRN SMIM5 FAM174B C10ORF95 PIM2 DNAH7 MICAL3 PDGFA CST6 SLC14A2 ADRB1 OXT PIH1D3 STMND1 PLXNB1 SPINK7 ZBBX SERPINI2 ZBTB4 MLLT4 FXYD3 INHBB TRA2A FANK1 AK9 TTC26 FAM227B MBOAT2 ARHGEF38 GNRH2 ADAMTS13 ZNF749 GPR82 ABCA5 LTBP1 DNAH9 CYP4X1 TTC36 PON3 MAT1A IGFALS SCGB1D4 BIRC7 PIH1D2 KIF9 PALMD TOMM7 MOK CAPS DNLZ RIBC2 MRPS21 TLL2 KIAA1211L LCA5 ZBTB7C HEG1 PCDH7 IGF2BP2 APBB2 ZCCHC14 RAB27B MACROD1 ECI1 MAGIX ZNF516 PPP4R4 IQCK SPA17 SEMA3D ARHGEF9 C1RL SLC7A2 VAV2 RASSF9 EAF1 C7ORF57 SPAG17 CCDC146 DNAH12 WDR60 FAM177A1 ARHGAP42 SPAG1 OVOL2 ANKRD26 ANKRD37 DNAL1 ARHGAP39 HSD11B1L UPF3B TNXB CSPP1 PDE6B C11ORF52 CCDC39 KLC2 SNAPC4 SPSB2 POLR2I GPR124 TTC25 KIAA1377 NPHP1 TRAF3IP1 EFCAB2 CCDC176 CRYBG3 HAGHL C6ORF170 AGL C1ORF173 CLIC6 FAM154B SPATA6L ODF2L PCDP1 NEIL1 RAB17 AZI1 LRRC71 KRT40 CGB CAPN9 DNAH2 MKX TBX1 IFT27 FAM227A SCGB2A1 WDR66 CCDC125 AMY2B ALDH3B2 OFD1 BEX5 MORN1 CCDC122 FAM200B CCDC181 TTLL3 AK7 ZGLP1 NSUN7 ADGB CALML4 NWD1 C9ORF135 LRRIQ1 SPEF2 C7ORF41 FBP2 C14ORF37 PACRG CCDC154 LRRC6 ATP5S DNAH10 PPP1R36 KNDC1 TTLL10 FAM184A FAM184A SYTL4 TTLL9 ALS2CR12 SLC6A16 CHCHD5 IQCA1 DTHD1 DYDC2 C8ORF47 OPRL1 PAPPA2 ZC2HC1A C5ORF38 IRX2 C2ORF54 MORN3 NEK11 C7ORF63 ZMAT1 FAM221A CCDC148 CCDC33 C1ORF192 KIAA1456 DNAH3 WDR16 CCDC147 WDR96 DNAH11 IQCG WDR93 PLAG1 TTC23L C9ORF117 NEK5 FAM81B ZSWIM7 PCNXL4 HDGFRP3 C12ORF40 MNF1 CCDC13 C9ORF174 IRX3 C20ORF201 CHRNA9 CC2D2A CCDC151 C2ORF62 SSPO PLEKHG4B RGS13 C11ORF88 DYX1C1 PTPN20B FAM25A CCDC11 DYDC1 CFAP99 C1ORF168 CCDC37 C2ORF71 CCDC19 CIB3 DNAH6 CD164L2 MC3R DPRX MAK CAPS2 KIAA1407 MORN2 GAS2L2 EFHB TTC40 C1ORF228 CCDC164 SAPCD1 WDR52 DNAJB13 CCDC108 CEACAM4 RHOXF2B NRG2 C17ORF66 C2ORF70 PPP1R42 C1ORF141 CDKL4 SPATA17 CDK15 DNAI1 CCDC41 ENKD1 DPP6 Top 500 up genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 SLC36A1 FOXRED2 DPP4 CCL5 CMA1 TMEM37 TGM4 ADAMDEC1 AADAC ICOS JAKMIP1 PLA2G2D GALR2 NPC1L1 ADAM9 CLCN6 PIGO TREM2 TCN2 GGCX SLC27A4 CTSD FASLG GIPC2 TSPAN8 PLD3 CD7 FYN APOBEC3G SIRPB2 CD8A VSIG4 UBQLN2 SCARB1 FRMD8 PCMTD2 TM7SF3 METTL7A LRRC61 CPT1A CDK5RAP1 TMEM86A NAGLU ITGA2 ASS1 SLC40A1 TTC39A ECM1 RPS15A AQP5 UPK1B CCNO CD180 CYBRD1 CLCA2 RGL1 CEACAM5 PLA2G7 GABRP TMEM184B OGDH TOR3A GAA MYADM APOL2 ITGA5 GRN ABCC3 SLC38A7 ZNF100 SCARB2 CTSB CYFIP1 NREP SLC16A1 KCNK13 FLT3 CDCA5 LHFPL2 STARD13 TDRD9 DLGAP5 BUB1 GPNMB RRM2 SLC1A3 CLEC1B MAFB HGF SPRY2 C2 CALCRL CCR2 IGLL5 PADI2 CDC20 CLEC12B MKI67 DTL RNASE3 CD247 UPK3B CCR9 A2M S1PR5 SLC2A9 WDR72 TGFBR2 SLC2A5 MPEG1 B3GNT9 C1ORF106 CDH3 ALPL WNT2B LAMP1 ELP3 RNF26 UBE2Q2 SLC24A3 CXCR3 SLC37A2 KLRC1 IL10RA SELPLG NKG7 DENND1C FANCI CAMK4 CD28 TLR1 FAM83D SLC29A3 CD27 IGJ CXCR6 LCK IL2RB KNTC1 PIK3R5 GZMA LANCL3 TACC3 GP2 RACGAP1 ITGB7 TRAIP GPR31 CCNF CCR5 GZMK EOMES GPR171 GSTA5 PSAT1 SLC7A8 OAS2 C3 SIGLEC1 COCH GINS1 SEPT3 PREP MCOLN2 HPSE SLC39A14 C5AR1 MAMDC2 HCN1 EPHA1 ACER2 SEPT4 RASGRP3 SPARC CLDN18 IFI44L CCKAR GIMAP8 ARRDC3 CHST1 FUCA1 CSF1R GIMAP4 PDPN GNS THEMIS2 NRP1 MARCKSL1 CYP2S1 PDZRN3 PLCL1 IL16 NOS2 NCKIPSD P2RY12 GPRIN3 FUT2 AKR1E2 CYTIP ASB2 RTN4R RADIL ADRA2A DEPDC7 GALNT7 TSPAN4 SMIM6 TNFRSF21 SEC24B LRP11 ATP2C1 SOAT1 NCOA4 ZMAT3 TMEM47 SAMD4A DLG4 IP6K3 DIAPH3 PCNXL3 LRRN4 PCYOX1L SERPINB7 FAM189A1 GRAMD4 PRF1 ADRB3 DNASE2 AVIL SLFN5 MARS2 F13A1 SLC16A12 NCKAP1L DERL3 PIK3CG SLAMF6 FES GIMAP1-GIMAP5 FAIM3 SLC6A4 FAM171A1 KBTBD7 IDH2 PRPS2 TTC31 MX2 HYAL4 SLC47A1 PAQR8 GJB2 P2RY1 ZNF426 TMEM62 AZU1 PRTN3 MPO PRKCH GZMB GNLY ADAM10 ST6GAL1 ITGAD KLHDC8B GRAMD1B FADS2 DNM1 APBA1 OLFML3 SDC3 ENPP2 CDC20B C6ORF10 NR2E1 ABO CGA NPTX2 CECR1 MAST1 LPO TYRO3 GLE1 KRBOX1 APOBEC3F SIGLEC14 NPC1 BCR TXNDC5 ADPGK PLBD2 ARAF LDHC WIPI1 SLC35A4 SEC23IP RDH16 NNT ABHD12 SLC46A2 SLC25A10 TPCN1 CHST4 CHST10 REC8 STT3B ZNF558 SMS HECTD3 MFSD12 LILRA1 TENM1 TPP1 JAK3 SLC38A5 CTPS1 VPS54 UCK2 SGPL1 TNFRSF11A NLRP3 CPM KLF8 NFAM1 MPDZ NUP160 MEGF9 GANC ABCC10 FER1L5 PITPNM2 TPBGL SLCO1A2 SLC9A9 SLC19A1 PRR5 VAC14 CMKLR1 FPR3 ATP13A2 FOXP3 UBIAD1 FANCC TTI1 HPS3 ZNF225 ZNF45 ERCC2 NCAM1 ULBP2 HAVCR2 PTGIR GIT2 CYP2U1 GJB1 SLC15A4 SGPP1 APBA2 CREB3L1 ANAPC1 NUP205 AKR7A2 ST8SIA4 TOP3B CRTAP PLOD3 TMED3 DSE SEC24D SFXN2 CENPT HES6 ZP3 TRIM47 TMEM135 VANGL2 PADI3 FAM198B LPCAT3 LRRC8C ATRN USP38 MED16 PPFIBP2 APEH LMF2 YIF1B PPIL2 SLC35F6 LPAR5 FBXL18 NDST2 TMEM117 GIMAP6 GRAP NRSN2 DNAJC1 COL15A1 TTYH2 RBP1 BLOC1S3 SLC35G1 ALDH18A1 ERP27 KIAA0196 DFNA5 PALD1 LDLRAD3 SUSD1 GPR146 TPCN2 ADCK1 POLR1B P2RX1 PRKCQ PMEL CCDC87 SLC44A1 SOGA2 SYNC UBAC2 SPIN3 FBXO30 GHDC C2CD5 ELMO1 SLC43A1 FBXO41 FOXN4 SH3RF3 EPHX3 MTPAP SLC5A7 MUC12 PLEKHM3 PRICKLE4 PCDHGA6 DACT3 KIF7 C11ORF45 CHST12 DLEU7 LRRC8D BAIAP3 IGSF1 ZNF846 IL20RA CHRNA3 CHRNA1 USP30 UNC5D PHF17 ANKRD36 EVC JAM3 ZKSCAN7 SYT5 ZNF354C KCNJ1 ARHGAP22 LAMB4 MTL5 C16ORF89 EDIL3 TMEM255A APOBEC3H DNASE2B EXD2 CCDC36 C1ORF216 PPT2 LEPRE1 PYHIN1 PRR18 HIATL1 SIRPG CCKBR CA5B CDYL2 TIGIT SLC24A6 STARD8 ZNF417 NKX2-8 TAS1R1 SS18 LEPREL1 KIAA1467 UPK3BL MCIN CNIH2 OR6B2 TEX33 RTP1 TMEM26 IRGC CNGA4 CT62 ERV3-1 TANGO6 C6ORF15 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 CEP112 GCC2 NINL WFIKKN1 SLC6A20 ACE2 GPT TPRN RYBP SULT1B1 QSOX2 TREH AGT CSNK2A2 FAU AKAP9 PPIG BDKRB1 FBP1 CHD1 PLEKHA5 NOL7 PKIG GADD45GIP1 XPA PFDN5 NBEA ENKUR TMC5 TFF3 OSBPL6 FAM229B ARL3 ALMS1 MUC15 NEK10 KIF21A C9ORF116 MAP3K19 NFIB SPAG16 HUNK FNBP1L C9ORF24 SETBP1 CRCT1 FMN1 MAPK10 FAM183A TFF1 C2ORF73 ANK3 DCDC1 MAP7 RPS7 ENPP4 HBEGF RHOB MACC1 MT1F UACA ADAMTS2 SLFN11 IFI27L2 C5ORF30 B4GALNT3 LRRC43 CPA3 PER3 TNRC6C PDZD4 BAD HINT2 BMP4 CDH1 HPGDS EDN1 CLDN3 NAV2 FGF12 CBLN4 FZD8 JAG1 HNRNPH1 SORCS1 MAB21L1 PWWP2B TNK2 RXRA SETD1B LY86 PON1 CCL24 CLEC6A EFCAB11 CLEC4E RAMP1 INHBA PTPRT APOC2 GDF1 TSPAN13 CD200 TNNC1 COX17 CLIC3 GATA2 NDUFA3 FBXO16 PRDX5 C19ORF43 S100A6 NDUFS6 CETN2 C6ORF57 EID1 SHFM1 RPL35 FAM189A2 SOD1 NDUFC1 MYEOV2 MBLAC1 CETN3 USMG5 CDK11A YTHDC1 USHBP1 C8ORF59 PIN4 GLOD4 NDUFA7 SCAND1 TMEM256 S100A13 DEK LCA5L SELM PNLDC1 SLC5A10 ALOX12B GPR111 C6ORF52 EDNRA TMEM52 CYP2A13 FUS CMIP PROC C17ORF96 SERTAD1 TMEM258 DPM3 MMP10 EMC4 MSRB2 PFDN2 NKAP DLG2 IMMP1L LSM7 PTMA RPAP3 CMC1 FAM60A HSPE1 CNFN WFDC3 MNS1 C15ORF65 RRAGC ATP5E MT1H MEIG1 CTDP1 RPA3 TCTEX1D2 PSD3 SLIRP RIIAD1 CCDC153 FAM161A PIGZ GCHFR SNX20 PTGDS WDR86 TPGS1 TMEM40 TNN VMO1 GPRASP1 PRPF38B CD1B KIAA1211 CCDC68 ARL13B SEC62 IFT74 TOP1 TMEM107 EIF5B PPP1R9A IGF1R YY1 CCDC173 XRCC4 CEP290 RSF1 CEACAM1 RBM34 CTNNAL1 FMR1 BTC ENO2 U2AF1 SERF2 TCEB2 LAIR2 SON PIK3R3 IL17D CACNA2D3 TMEM255B TCEAL2 TRPM3 CCDC34 C4A BDKRB2 GTF2H5 PET100 UBE2B HLX NDUFB1 FKBP2 UBALD2 MAPKAPK2 COX19 SYAP1 ANKRD18A AIG1 AURKAIP1 CDC42BPB C19ORF53 C11ORF58 HEPHL1 MRPL52 KTN1 KCNJ2 CEP63 RBBP6 EIF3J FILIP1 USP16 WBP4 TEX9 IFT81 ATXN1 TMEM91 HOXB6 MARCH4 ITPA NOXO1 CHST3 KIRREL3 KCTD15 METRN SMIM5 FAM174B PIM2 RTN3 SREK1 PDGFA CST6 PURA ADRB1 OXT STMND1 SPINK7 ZBBX ZBTB4 MLLT4 CHD6 FXYD3 INHBB RRAS2 TRA2A FANK1 ZCWPW2 AK9 MSRB3 ARHGEF38 SYNJ2 FIS1 FAM133B IDO2 RSBN1L HYPK CYP3A7 GPR82 ABCA5 LTBP1 DNAH9 TRIP11 TTC36 PON3 MAT1A LAMA4 SLC18A2 SCGB1D4 HOXB4 BIRC7 TRMT6 TEF LATS2 CDK12 USE1 MT1G AK1 MRPL23 PALMD DYNLRB1 ANAPC16 TOMM7 GCSAML MOK DLC1 DNLZ MAOB MRPS21 UBN2 IGF2BP2 ZC3H6 ZDBF2 ZCCHC14 RAB27B MACROD1 ECI1 MAGIX PCF11 SNRPF TTLL7 HNRNPA3 LRRCC1 SPA17 SEMA3D ARHGEF9 C1RL SLC7A2 RBM25 ZNF92 RASSF9 TCTE3 EAF1 PIGX PCMTD1 C7ORF57 CCDC146 RSBN1 PLA2G16 AES DNAH12 WDR60 FAM177A1 ARHGAP42 ANKRD26 ANKRD37 DNAL1 ANKRD2 UPF3B CCDC39 KLC2 C16ORF55 SPSB2 POLR2I LSMD1 GPR124 CEP164 KIAA1377 TRAF3IP1 EFCAB2 AGL C1ORF173 CCR10 CLIC6 SPATA6L ODF2L RAB17 CAPN9 MKX YRDC IFT27 SCGB2A1 WDR66 CCDC125 AMY2B ALDH3B2 OFD1 SRCIN1 BEX5 MORN1 CCDC122 TRIM44 SMIM4 FAM200B CCDC181 AK7 ZGLP1 NSUN7 ADGB CALML4 ALPK2 C9ORF135 LRRIQ1 CIR1 SPEF2 C7ORF41 PFN4 C14ORF37 CCDC154 LRRC6 KAZN GPATCH2 ATP5S CDH23 UPF2 ABRA FAM184A FAM184A SLC6A16 CCDC66 CHCHD5 IQCA1 C12ORF65 DYDC2 C8ORF47 C10ORF118 PAPPA2 GMNC VGLL4 ZC2HC1A IRX2 C2ORF54 MORN3 C7ORF63 ZMAT1 CCDC148 DNAH11 FAM81B ZSWIM7 HDGFRP3 C12ORF40 MNF1 C9ORF174 C22ORF32 C20ORF201 CHRNA9 CC2D2A C11ORF83 KIAA0825 SSPO PLEKHG4B RGS13 C11ORF88 CD1E DYX1C1 PTPN20B CCDC11 ACER1 DYDC1 PRR24 C1ORF168 CCDC19 CIB3 OR6V1 CD164L2 MC3R DPRX MAK CAPS2 KIAA1407 EFHB TTC40 C1ORF228 WDR52 ACYP1 DNAJB13 CEACAM4 NRG2 LRRC14B C17ORF66 C9ORF142 PSD C2ORF70 PPP1R42 CDKL4 PRSS54 CCDC41 C11ORF91 KRTAP3-2 Top 500 down genes for SARS-CoV-2 infection in Rhesus macaques at Group 3 dose in Bronchoalveolar Lavage at 14 DPI from GSE156701 In this experiment, 9 adult rhesus macaques (6 to 12 years of age) were exposed to 3 different levels of SARS-CoV-2 doses at 6 timepoints, and data was collected from 2 tissues; this entry involves bronchoalveolar lavage (BAL). Refer to provided metadata for the parameters of this specific set of samples. Associated with this publication: Aid M et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Cell 2020 Nov 25;183(5):1354-1366.e13. PMID: 33065030 UBL5 CEP112 GCC2 NINL WFIKKN1 SLC6A20 ACE2 GPT TPRN RYBP SULT1B1 QSOX2 TREH AGT CSNK2A2 FAU AKAP9 PPIG BDKRB1 FBP1 CHD1 PLEKHA5 NOL7 PKIG GADD45GIP1 XPA PFDN5 NBEA ENKUR TMC5 TFF3 OSBPL6 FAM229B ARL3 ALMS1 MUC15 NEK10 KIF21A C9ORF116 MAP3K19 NFIB SPAG16 HUNK FNBP1L C9ORF24 SETBP1 CRCT1 FMN1 MAPK10 FAM183A TFF1 C2ORF73 ANK3 DCDC1 MAP7 RPS7 ENPP4 HBEGF RHOB MACC1 MT1F UACA ADAMTS2 SLFN11 IFI27L2 C5ORF30 B4GALNT3 LRRC43 CPA3 PER3 TNRC6C PDZD4 BAD HINT2 BMP4 CDH1 HPGDS EDN1 CLDN3 NAV2 FGF12 CBLN4 FZD8 JAG1 HNRNPH1 SORCS1 MAB21L1 PWWP2B TNK2 RXRA SETD1B LY86 PON1 CCL24 CLEC6A EFCAB11 CLEC4E RAMP1 INHBA PTPRT APOC2 GDF1 TSPAN13 CD200 TNNC1 COX17 CLIC3 GATA2 NDUFA3 FBXO16 PRDX5 C19ORF43 S100A6 NDUFS6 CETN2 C6ORF57 EID1 SHFM1 RPL35 FAM189A2 SOD1 NDUFC1 MYEOV2 MBLAC1 CETN3 USMG5 CDK11A YTHDC1 USHBP1 C8ORF59 PIN4 GLOD4 NDUFA7 SCAND1 TMEM256 S100A13 DEK LCA5L SELM PNLDC1 SLC5A10 ALOX12B GPR111 C6ORF52 EDNRA TMEM52 CYP2A13 FUS CMIP PROC C17ORF96 SERTAD1 TMEM258 DPM3 MMP10 EMC4 MSRB2 PFDN2 NKAP DLG2 IMMP1L LSM7 PTMA RPAP3 CMC1 FAM60A HSPE1 CNFN WFDC3 MNS1 C15ORF65 RRAGC ATP5E MT1H MEIG1 CTDP1 RPA3 TCTEX1D2 PSD3 SLIRP RIIAD1 CCDC153 FAM161A PIGZ GCHFR SNX20 PTGDS WDR86 TPGS1 TMEM40 TNN VMO1 GPRASP1 PRPF38B CD1B KIAA1211 CCDC68 ARL13B SEC62 IFT74 TOP1 TMEM107 EIF5B PPP1R9A IGF1R YY1 CCDC173 XRCC4 CEP290 RSF1 CEACAM1 RBM34 CTNNAL1 FMR1 BTC ENO2 U2AF1 SERF2 TCEB2 LAIR2 SON PIK3R3 IL17D CACNA2D3 TMEM255B TCEAL2 TRPM3 CCDC34 C4A BDKRB2 GTF2H5 PET100 UBE2B HLX NDUFB1 FKBP2 UBALD2 MAPKAPK2 COX19 SYAP1 ANKRD18A AIG1 AURKAIP1 CDC42BPB C19ORF53 C11ORF58 HEPHL1 MRPL52 KTN1 KCNJ2 CEP63 RBBP6 EIF3J FILIP1 USP16 WBP4 TEX9 IFT81 ATXN1 TMEM91 HOXB6 MARCH4 ITPA NOXO1 CHST3 KIRREL3 KCTD15 METRN SMIM5 FAM174B PIM2 RTN3 SREK1 PDGFA CST6 PURA ADRB1 OXT STMND1 SPINK7 ZBBX ZBTB4 MLLT4 CHD6 FXYD3 INHBB RRAS2 TRA2A FANK1 ZCWPW2 AK9 MSRB3 ARHGEF38 SYNJ2 FIS1 FAM133B IDO2 RSBN1L HYPK CYP3A7 GPR82 ABCA5 LTBP1 DNAH9 TRIP11 TTC36 PON3 MAT1A LAMA4 SLC18A2 SCGB1D4 HOXB4 BIRC7 TRMT6 TEF LATS2 CDK12 USE1 MT1G AK1 MRPL23 PALMD DYNLRB1 ANAPC16 TOMM7 GCSAML MOK DLC1 DNLZ MAOB MRPS21 UBN2 IGF2BP2 ZC3H6 ZDBF2 ZCCHC14 RAB27B MACROD1 ECI1 MAGIX PCF11 SNRPF TTLL7 HNRNPA3 LRRCC1 SPA17 SEMA3D ARHGEF9 C1RL SLC7A2 RBM25 ZNF92 RASSF9 TCTE3 EAF1 PIGX PCMTD1 C7ORF57 CCDC146 RSBN1 PLA2G16 AES DNAH12 WDR60 FAM177A1 ARHGAP42 ANKRD26 ANKRD37 DNAL1 ANKRD2 UPF3B CCDC39 KLC2 C16ORF55 SPSB2 POLR2I LSMD1 GPR124 CEP164 KIAA1377 TRAF3IP1 EFCAB2 AGL C1ORF173 CCR10 CLIC6 SPATA6L ODF2L RAB17 CAPN9 MKX YRDC IFT27 SCGB2A1 WDR66 CCDC125 AMY2B ALDH3B2 OFD1 SRCIN1 BEX5 MORN1 CCDC122 TRIM44 SMIM4 FAM200B CCDC181 AK7 ZGLP1 NSUN7 ADGB CALML4 ALPK2 C9ORF135 LRRIQ1 CIR1 SPEF2 C7ORF41 PFN4 C14ORF37 CCDC154 LRRC6 KAZN GPATCH2 ATP5S CDH23 UPF2 ABRA FAM184A FAM184A SLC6A16 CCDC66 CHCHD5 IQCA1 C12ORF65 DYDC2 C8ORF47 C10ORF118 PAPPA2 GMNC VGLL4 ZC2HC1A IRX2 C2ORF54 MORN3 C7ORF63 ZMAT1 CCDC148 DNAH11 FAM81B ZSWIM7 HDGFRP3 C12ORF40 MNF1 C9ORF174 C22ORF32 C20ORF201 CHRNA9 CC2D2A C11ORF83 KIAA0825 SSPO PLEKHG4B RGS13 C11ORF88 CD1E DYX1C1 PTPN20B CCDC11 ACER1 DYDC1 PRR24 C1ORF168 CCDC19 CIB3 OR6V1 CD164L2 MC3R DPRX MAK CAPS2 KIAA1407 EFHB TTC40 C1ORF228 WDR52 ACYP1 DNAJB13 CEACAM4 NRG2 LRRC14B C17ORF66 C9ORF142 PSD C2ORF70 PPP1R42 CDKL4 PRSS54 CCDC41 C11ORF91 KRTAP3-2 Top 500 up genes for SARS-CoV-2 infection 48 hpi in human alveolar organoids for GSE152586 Bulk RNA-seq was performed using human alveolar type II cell organoids at 48 hours after SARS-CoV-2 infection. Associated with this publication: Katsura et al. (2020) Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell, 27(6):890-904.e8. PMID: 33128895 RSRC2 CAPN5 STAT3 NMI UBXN2A DDX58 TBK1 RIPK1 MYO1D CCND3 BAIAP2L1 IFITM3 CYP2J2 IFITM1 NDRG1 VILL LAP3 RUNX1 JAK2 BAG3 SMAD3 BRD2 RBCK1 OAS1 GRIPAP1 BIRC2 PLOD2 STAT1 TRIM25 EIF2AK2 TMEM173 FOXA1 OASL MOV10 MAT2B IFNB1 TTC38 ISG15 MARK2 AKAP8L NUB1 MX1 MYD88 SIPA1L1 NR3C1 PLEKHA7 LIFR FZD5 N4BP2L2 SERPING1 MT2A SDC1 TNFSF10 KLF5 IFI27 RBPMS ERBB3 NT5E SLC4A4 RAI14 CXCL17 LRIG3 ELF3 PPL LMO7 TOX3 OSMR KIAA1217 PNRC1 COLCA1 CFH GALNT3 HIST1H2BK HIST1H2BD HIST1H2AC ISG20 NEDD4L TAB2 ATP10A CMTR1 UNC93B1 USF1 PARP10 LGALS3BP TOR1B C15ORF39 MICAL1 RFX5 GRINA PTK2B APOL1 LRP10 TYMP BST2 SLC16A3 SLC15A3 APOL2 HLA-E FBXO6 SCARB2 C5 SLC16A1 LDLR STS IFI44 EPSTI1 SPRY2 C2 BATF2 SPATS2L LDHA LIPA YES1 TJP3 BMPR1A B4GALT5 GADD45G GADD45B FAM20A ZBTB42 AGRN FAM84B KIAA1522 SCNN1A GRHL2 SEMA4B JAG1 MAP2K6 CTSC MED25 TPBG AP5B1 TMEM63B HELZ2 NUAK2 OGFR MIDN RSAD2 OAS3 IDO1 IRF7 ZBP1 NLRC5 TAP1 IFIT1 SECTM1 CLEC7A CTSS IFIT3 RTP4 PRSS22 SLC7A8 HLA-F OAS2 C3 PHF11 XAF1 PSMB8 CD274 APOL6 GBP4 DHX58 C1R TREX1 USP18 CMPK2 CA13 IFIT2 IFI16 HERC6 IFIH1 MLKL STAT2 PML PLEKHA4 TCIRG1 SOCS3 ADAR GBP2 NT5C3A PARP9 PARP12 SAMD9L HSH2D CASP4 RNF213 IFI35 PARP14 SOCS1 TRAFD1 SAMHD1 UBE2L6 AIDA TLR3 UBA7 WARS SP110 ATP13A4 TSC22D1 IRF2 EHD4 SHISA5 LY6E IRF1 PSMB10 RASGRP3 TGM2 TXNIP DTX3L NFKBIA ST5 IRF9 ITM2B JUNB PSMB9 SH3BGRL DRAM1 VEGFA IFI44L RNF114 TAPBP GLUL BNIP3 ARRDC3 CCNL1 DNAJA1 FEZ2 NRP1 GTF2B RASSF5 MYO18A RAB3GAP1 NXF1 TRIM22 TNFAIP3 MUC1 STC1 AQP4 AMOTL2 DUSP5 IER5L IRF2BPL CSRNP1 BHLHE40 NFKBIZ ZNFX1 PDLIM1 CHMP5 TMX1 DYNLT1 LYSMD2 PNPT1 STAU1 GPBP1 CUL4B MKRN1 ID1 INSIG1 RRAGC RNF19A DENND5A NECAP1 ODF3B STXBP1 SLC6A9 SLFN5 TLR2 CASP1 PPM1K CSF3R ETV6 LGALS8 TRIM21 RNF31 USP25 TRIM56 ZC3HAV1 TRIM5 RBM43 TDRD7 TRIM14 PCGF5 AZI2 ANKFY1 CD38 PRKD2 PCSK9 GABRE IFI6 FNBP4 APCDD1 CFI DDX60 C9ORF91 SLC25A28 TIA1 STARD4 RNF19B C19ORF66 LGALS9 TNFSF13B XRN1 SP100 RARRES3 MX2 IFIT5 HERC5 TRANK1 DDX60L TMEM140 SAMD9 GBP1 CASP7 ST3GAL1 TOP1 KIAA1033 CEACAM1 CDK17 SIDT1 ETV7 BTN3A3 GMPR BAZ1A CLUHP3 ARL5B PATL1 NAPA SP140L C5ORF56 N4BP1 RBMS2 WHAMM TMEM62 BTN3A1 C1S MOB3C IRS1 TRIM38 JADE2 RABGAP1L PARP8 TRIB2 BLZF1 FMR1 SCAMP1-AS1 BLNK BTC PARP3 PHACTR4 OPTN GTPBP2 RNF149 SERPINA1 ERBB2IP CAST PIK3R3 PRKAG2 PTPRE KIAA0040 CLK1 DAPK2 PLSCR1 NR1D1 HRASLS2 CD68 LOC100419583 B3GNT6 PGK1 TWF1 CARD16 BCL2L14 DPP9 IFNGR2 SNX6 UBALD2 SQRDL PI4K2B CYTH1 SMURF1 UBA6 KCNJ15 C4ORF3 C6ORF62 SLC46A2 CTNNBL1 ST3GAL5 ERAP1 RBBP6 ALDOC TMEM123 P4HA1 PPP2R2A ZFYVE26 TLE4 PIM2 ACSL1 BCL6 DAPP1 NBN GBP1P1 FLOT1 SERTAD3 EPC1 KAT2B ITGA3 ACBD3 SP1 CHD8 KDM3A KDM4A GOLM1 USP28 ZBTB18 DAB2IP CHD2 ARHGEF38 IL6ST MAP3K5 STX17 AMBRA1 ZFAND5 WDFY1 TNFSF13 TFPI CPQ RABGAP1 BCL2L13 IL13RA1 GTPBP1 PARP4 TNC WSB1 STARD5 SUSD6 TMEM219 CLDN23 FLNB TNKS2 FNDC3A SMG7 C6ORF223 TTC39B ENDOD1 CCDC6 NHLRC3 KDM5B CNP KCNK5 RNF43 OSBPL10 ELF1 USP6NL FBXO34 SPATA13 RAB27B CDK18 ANKRD10 KMT2E PHF21A INTS12 RGMB RAI1 ARID4B TLK2 C1RL PNRC2 BAZ2A CHD9 ZRSR2 BTN2A1 PHYKPL C4ORF33 ANKIB1 ZMYND8 CCSER2 FYTTD1 SMIM14 TSC22D4 ORF7A ORF1AB ORF3A DCBLD1 HIAT1 SLC18B1 ELMO2 LARGE YEATS2 AP1G2 SPG20 TMEM125 ORF6 ORF8 ORF7B ORF10 TMEM110 GRAMD3 MBL1P C8ORF34-AS1 ARHGAP44 LINC01000 Top 500 down genes for SARS-CoV-2 infection 48 hpi in human alveolar organoids for GSE152586 Bulk RNA-seq was performed using human alveolar type II cell organoids at 48 hours after SARS-CoV-2 infection. Associated with this publication: Katsura et al. (2020) Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell, 27(6):890-904.e8. PMID: 33128895 FOXRED2 DCTPP1 IMPDH2 TIMM8B GDF15 CTSL GHITM YWHAQ ETFA SLC6A20 PUSL1 ARRB2 ACAD9 YIF1A NDUFAF2 ACSL5 MRPS2 STOML2 ASPSCR1 SIGMAR1 GPX1 FBL PMPCA SLC27A4 TUBA1C PABPC4 TUBA4A NUTF2 MGAT4B NDUFB9 PEPD PHB RCC1 NPM1 HSPA8 THOP1 PTGES2 HKDC1 SCARB1 DPH5 GGH PLP2 NAP1L1 SLC25A39 MDH1 ATAD3A RABEPK FAH HIBCH GADD45GIP1 CISD1 WDR34 SLC25A16 NDUFV1 NDUFB6 GSTZ1 ACO1 MCAT SAC3D1 C20ORF27 TBCB RPS26 DANCR NT5DC2 NDUFB2 CKS2 SNHG16 CHCHD10 AADAT FTL BAX TOMM40 STMN1 THBS1 SNRPB EIF3B INF2 ARHGDIA PYCR1 TOP2A MRPL37 ZWINT MRPL12 CCNB2 TUBG1 CDKN3 AREG SPR NDUFS7 MTCH2 AP2S1 RENBP MRPL15 KNSTRN FH AURKA SHMT1 CDK1 CDC6 BIRC5 PRDX1 SAPCD2 HSD17B10 G6PC3 NME1 CCNB1 CEP55 GRHPR CDC20 PRDX3 PRELID1 MRPL51 AIMP2 GNPDA1 AKR1C3 CYCS HMGA1 TRIM16 SLC2A4RG MCCC2 PRC1 UBE2T GINS2 H2AFX CENPM DNPH1 DHFR ALDH1B1 TNFRSF12A FTH1 YBX1 TUBA1B ATP5G3 PEBP1 TXN TPPP3 ATP5J TSPAN7 CHCHD2 H2AFZ PLIN2 EIF3I CCT2 MDH2 ACAT2 EIF3K PSMB6 COX8A EIF5A ATP5D MRPL20 PSMB5 NDUFS6 TMEM160 ABRACL QDPR HADH NDUFB7 H2AFY STUB1 LAMTOR1 RAN CCT3 TALDO1 ROMO1 TRMT112 KLHDC3 HN1 MYEOV2 LBH VDAC3 EFHD2 NOP10 USMG5 TRUB2 GLRX5 CHCHD1 RPS27L ATP5J2 NDUFB10 GPX4 TMEM147 CACYBP QPCTL NDUFS2 UBE2S MRPL34 UBE2M NQO1 MRPL24 BABAM1 RRM1 C19ORF70 SRM POLD2 DCXR RNASEH2A AP1S1 PTTG1 HMGB1 WRB SLC25A11 APOA1BP PARK7 MRPL13 PSMB3 PSME3 COPRS AHCY CCDC124 NHP2 EBNA1BP2 NPM3 MRPS35 BOLA3 ACTL6A UQCRQ TSPAN4 PIH1D1 RCN2 MRPS23 POLR2E NDUFA12 PTDSS1 FAM107B PSMD14 POP5 NAA50 PSMA7 UQCRH CCT7 RUVBL1 ADSL AKR1B1 NAA10 TUFM IPO5 PFN2 NAA20 HSPE1 SNRPE SF3B5 ETFB TOMM5 CDK4 TCP1 ODC1 RUVBL2 ADORA2B GOT2 HSPD1 MLH1 SRXN1 SURF2 ORAI1 CINP CSRP1 CDCA7 DHRS13 TRIAP1 PTS BCL2L12 POLR3H RASD1 GCAT TFRC ALDH3A1 NUDT1 IARS SNRNP25 RFC2 LRRC45 PPIL1 MRPS11 RPL22L1 MLEC BOP1 TCTA REEP4 VAT1 TM7SF2 CMTM4 RSU1 CTSA UQCRFS1 BLVRB COX6C OSGIN1 TRIM16L NR4A1 PLA2G4F SP5 PRDX2 IRAK1 TRAPPC1 SAMM50 SNRPD3 TRAPPC4 UBL4A TXNL4A UCHL1 CLPP MRPS12 GNPNAT1 NUDT5 TXN2 USP5 PPP5C HMOX2 CARS2 FARSB SEPHS1 HTATIP2 SAE1 SUCLG1 ESYT3 NUDT8 AURKAIP1 COPS6 COA4 APRT ACAT1 CCT6A GGCT PLEKHJ1 STK25 SLC25A10 ARMC6 MRPL52 NUBP2 STRA13 DCAF13 KLHL21 COMTD1 PRKAR1B FAM173A BCAT2 ASNA1 ABCB6 ITPA TTLL12 AMDHD2 PRADC1 RPS19BP1 TBC1D7 ALDH16A1 KATNB1 CMC2 PYCR2 PPP1R14B CYC1 ILVBL TIMM13 UROD SIVA1 PC DUOX1 SSRP1 RAB40C DTYMK DDX27 GSR PGP RAB32 EIF4EBP1 MRPS7 ATP13A2 PGAM5 RPS6KB2 IMPDH1 GCSH GCLM AKR1C2 MRPS26 LIMK1 MTFP1 CHD1L GLS2 PIN1 NUDT15 ZMYND19 TIMM50 TARBP2 MRPL4 HN1L LSM4 HNRNPAB SHMT2 FAM207A RRS1 IFRD2 IPO4 MRPS34 AKR7A2 ENDOG SNRPC PLOD3 TUSC2 TPD52L2 NDUFS5 TIMM17A PDHA1 CDKN2AIPNL FITM2 ATP5B MFSD3 COMMD4 GPS1 C7ORF50 PXMP2 LAGE3 MRPL41 MAPKAPK3 PMVK HES6 TMEM141 TRAPPC2L NTHL1 MRPL3 EBP POLR3K H2AFV NDUFB8 FAM43A LOC100506548 ZDHHC12 HSPBP1 HDDC2 GPATCH4 ABHD14B STX10 NAA38 RITA1 NDUFS8 MLST8 MRPL55 LONP1 APEH ATP5G1 YIF1B C11ORF24 SNRPF SNRPD1 ATPIF1 C14ORF2 PHYH LSM3 UQCC2 SDHAF4 CBX6 DOHH PDCD5 OXCT1 PCCB PKN1 MRPS16 LSM10 PITHD1 CNIH1 DENR C21ORF59 NABP2 TMEM120A FAM177A1 ITGB1BP1 STRAP MINOS1 TSFM C17ORF89 MMP24-AS1 ALKBH2 MRPS28 ISCA1 UQCC3 FDX1L PSPH TMEM106C DUS1L TSR3 FAM195A SPSB2 POLR2I WBSCR22 MRPS17 PTRH1 C11ORF31 RPP25L B3GAT3 SMIM4 HDDC3 FAAP100 SNU13 C6ORF1 C19ORF60 TFB2M C8ORF33 GYLTL1B TMEM191A BCYRN1 SNORA25 Top 500 up genes in human lung AT2 cells organoids from GSE160435 Organoids generated from primary lung AT2 cells were either transfected with SARS-CoV2 virus or mock and isolated for mRNAseq. SRP19 CASP6 MISP UHRF1 HYOU1 NMI STX3 IRF3 CAPN2 MAP7D1 SLC1A1 DDX58 MPP5 CXCL10 CCND3 BAIAP2L1 CXCL16 EZR TPM4 ANXA3 ST14 FURIN LAP3 UBE2D1 PMEPA1 CTNNB1 ANXA11 SERPINE1 NFATC2IP OAS1 PSMC6 TUBA4A STAT1 TRIM25 EIF2AK2 MGAM OASL NUP88 NPLOC4 RCC1 PLS3 TTC38 YWHAH ISG15 DIAPH1 NUB1 CSF2 MX1 MYD88 PLEKHA7 VAMP8 ABHD3 MYO6 STXBP2 ALDH1A3 UCA1 CEACAM6 KRT18 TGFB2 KRT7 IFI27 GCNT3 SH3RF1 LURAP1L LMO7 CNN3 GALNT3 SERPINB2 GALNT5 APOBEC3A CYP2B7P C4ORF19 TJP1 GPRC5A ISG20 SLC25A23 GABRP ITPK1 TMEM184B CMTR1 PNPLA2 GPAT4 RIC8A DAZAP1 TOR1B C15ORF39 TYMP CORO1B BST2 TYK2 MYBL2 TK1 TWF2 MACC1 GTSE1 IFI44 FGD2 ITSN1 CDC6 EPSTI1 SH2D4A TP53I3 NECTIN2 CLDN7 BATF2 SPATS2L ARNTL2 NRIP1 ZNF365 PTGS2 ARVCF LLGL2 CDS2 TRAM1 CTNNA1 PIK3CA CRB3 ACTB EDN1 PLAUR TMOD3 RNF223 PROSER2 SH2D3A CNKSR1 LSR SERINC2 GIPC1 SLC52A2 SLC4A2 DKK1 HNRNPH1 UPP1 PREB DVL1 PSMA3 TRPV6 ZMYND15 PICK1 OGFR RAB43 RSAD2 OAS3 IDO1 IRF7 ZBP1 TCF19 NLRC5 TAP1 SLC29A3 MCM5 IFIT1 CORO1A GLIPR1 CYP1A1 IL36G IFIT3 RTP4 OAS2 CD86 PHF11 XAF1 CD274 APOL6 IL1R2 USP18 CMPK2 IFIT2 TIMELESS HERC6 IFIH1 MLKL PML TINAGL1 ADAR TNFRSF12A PARP9 PARP12 ARC SAMD9L HSH2D IFI35 PARP14 TRAFD1 SP110 EHD4 PSME2 CYTH3 ACTG1 MYL12A DTX3L IRF9 RHEB PXDC1 GBP3 TJP2 RBMS1 ACAT2 IFI44L TUBB ABRACL DHX15 TALDO1 PQBP1 DNAJA1 RTKN2 FNDC3B THEMIS2 PICALM S100A10 KIFC3 DUSP8 HDAC9 IL23A RTN4R SERTAD1 CLCF1 ZNFX1 HMGB3 MMP10 ATP6V1D NRBP1 ORMDL2 ZDHHC6 SLC44A3 TMPO ELOVL7 PNPT1 KCTD9 TMEM50A AMIGO2 SDF2L1 ARG2 ARHGEF18 MALT1 PTBP3 DUSP10 SRI RIPK3 MCU MMP9 C15ORF48 USP43 RND1 C3ORF52 CSRP1 SLC6A9 TAP2 SUSD3 MMP13 TRIM21 SPPL2A TRIM5 TDRD7 IL15 CD38 CYP1B1 LRRC42 CXCL11 IFI6 FAM111B DDX60 PHACTR3 PNKP PLEKHA6 APOBEC3B LGALS9 SP100 MX2 IFIT5 HERC5 DDX60L SAMD9 GBP1 SPAG9 WSB2 DNAJC3 LIPH SMURF2 LAMC2 TPRA1 TP53BP2 PIP4K2C HDX MICB TICAM1 SP140L RBMS2 TMEM62 SH3KBP1 BLZF1 MYL6 ILK PDXK CDA PTPRE TRIM16L SEMA7A HS3ST2 IL1RL1 SPOCD1 PLSCR1 CARD11 CDH2 TNFSF9 RUBCN POP4 PFDN1 UBE2J1 IFNLR1 UBE2B TNIP1 AGO2 CREB1 DPP9 FAIM UBAP1 PDCD1LG2 TMEM199 CYLD SMURF1 RNF34 PPP4R1 CREB3 AUP1 HAUS2 REC8 DNAJB11 CCNYL1 SMS NDOR1 PINK1 RALY HECTD3 FLII RNPEPL1 MFSD12 DDX39A OR7E14P HDAC7 ELK3 NCAPH2 RBFOX2 PPARD CST6 ACOT9 AGFG1 SPCS3 WDR1 SLC7A6 SPOCK2 SRF CDC34 LRRN1 FAM3C GOLM1 HIP1R RRAS2 PGP RAB32 RNFT1 RMC1 SLC8B1 NRAS CYP2A6 WWP2 ATP13A2 CD79A CTNS ANKLE2 SAP30BP CYP51A1 TRAF4 MET LPAR2 ILKAP CENPO GATA6 CCNC SLC35B1 PI4K2A CYB5R4 NANS CLDN23 ADGRF1 FGD6 BICD1 ABTB2 SKIL FSTL3 OSBPL7 EBP GMPPB CDRT1 TRIM47 TES CNP TMEM53 NR2F6 DNAJC9 IDS SENP2 KRT7-AS USP38 PPFIA1 HTRA2 VGLL1 NKILA PAFAH1B3 SHFL WARS1 AL161431.1 MPRIP DERL2 C1GALT1C1 CCDC107 ILRUN DDX23 RNF10 CCNDBP1 TSPAN17 ATAD3B TMEM63A ADPRHL2 SNAP23 DSN1 RAB3IP PROSER1 BCL7B DDX47 CACNB3 GPS2 DNAJB12 CLOCK SMG5 ZDHHC16 GPR180 ZGPAT CHMP6 SPATA2L KATNBL1 SCYL2 GPRIN1 MIIP DUSP3 ACTR5 ISY1-RAB43 DDX52 CXORF49 CXORF49B OVCA2 MFSD9 ALG13 TMC7 DMAC2 GPR37L1 KPNA7 CARD8-AS1 H2AX WDR55 PPP2R5B NAA60 SLC35D2 MON1B ALPP CAPN13 KRT87P AP000944.5 VIRUS_M MAB21L4 TTLL11-IT1 LINC01510 CYTOR NSUN5 VIRUS_ORF10 AC114488.1 FAM3C2 VIRUS_ORF1AB VIRUS_ORF3A AC022509.1 SLC49A3 VIRUS_ORF8 EIF1AD VIRUS_E VIRUS_ORF7A TLL1 AP003068.2 LINC00857 AL035461.4 AC013268.4 AC011511.5 AL662797.2 VIRUS_N VIRUS_1_261 RAB5IF VIRUS_ORF6 AC008764.4 VIRUS_S EXO5 TRBC2 Top 500 down genes in human lung AT2 cells organoids from GSE160435 Organoids generated from primary lung AT2 cells were either transfected with SARS-CoV2 virus or mock and isolated for mRNAseq. DCAKD CEP250 CES2 EEF1A1 EIF3F FKBP10 COL6A1 VCAM1 UGT1A7 LOX RPL12 THY1 COL4A5 HSD11B2 TYSND1 SLC22A18 CRYL1 FAM162A TCN2 HEPH ATM CYP2C18 FBN1 PLD3 PLAT ITGA4 POGLUT3 CD4 EPHX2 REEP6 GPHN PCMTD2 SIAE GPR155 PFDN5 NPHP3 SLITRK6 PCP4L1 TPRG1 RPL21 LINC01133 RPS12 FGF14 IL33 MT-ND1 MT-ND5 SLC4A4 MTRNR2L8 MT-ND6 LRIG3 RPS3A RPL21P16 H19 MT-ND2 RPL13A PTGFR MT-CO3 RPS25 ZEB1 PTN CLCA2 SSBP2 SPINK5 MT-CYB RPS18 ZNF467 MT-ND4 CRNN RPL31 ARID5B RPL7 H6PD GAA CD81 LRP1 CREG1 FZD2 ACCS MAFB PPARGC1B GSTM2 CXCR2 MMP23A ADGRB2 LAMA2 COL18A1 PTGDR2 A2M PTPRS COL6A2 TCN1 TGFBR3 ABCC9 NOTCH1 COL5A2 COL1A1 SERPINF1 COL14A1 SREBF1 SEMA4B FZD1 COL1A2 BNC2 LEF1 NKD2 FOXN1 DIXDC1 PODNL1 CRMP1 STMN3 VAT1L COL3A1 MAB21L3 CPXM1 ZNF711 ITGA8 CTHRC1 IGDCC4 ANGPTL2 INMT SCN7A TSC22D1 BTG2 FOS PLTP TMEM100 THRA EEF2 R3HDM2 SPARC BGN RPS19 PDE5A DDR2 LTBP3 PLXDC2 TCF4 PCOLCE EEF1G MEGF8 RGS5 COL6A3 PMP22 ZNF667 THBS2 PDZRN3 RRAD GLI3 STARD9 RGS14 COL13A1 ADAMTS10 CPT1C KCNE4 VAMP1 MXRA5 BMP5 EDNRA ZFP37 USH1G EGFEM1P SEZ6L2 FBXL16 CIDEB FAM216A CUTA L3HYPDH CTSO RPL34 SNHG8 FOXF2 ZP1 VAV3 ZMAT3 TNFRSF19 CLHC1 ZCCHC24 MAP1B RRAGB COL11A1 NTF3 GXYLT2 TMEM200A ELMOD1 PCDH9 PCYOX1L F10 PRRT2 EFNA3 LTB4R2 MFAP4 TMEM121 ROR2 MCHR1 PTGDS FETUB CYP4F22 FGFR3 NID1 RTN4RL1 TMEM68 PTGR2 CLGN TMEFF2 MT1X C8ORF88 LOXL1-AS1 BBS2 LAMB2 SMAD5 C10ORF99 TTC3 TMEM107 PIK3R1 CEP290 MRGPRF CA9 RNASET2 RPL36A SESN1 SLURP1 ZNF404 GAS1 ACTA2 LMOD1 RTN4RL2 DNM1 SLITRK5 LOXL2 PAMR1 COL12A1 ENPP2 ACTG2 RDH12 PIK3C2G TP73 ADH6 LAMC3 CXCL12 UPK1A KIAA1257 MASP1 KIT CYP2C9 PPARGC1A CA12 CTSF DENND2A GSTO2 CIRBP ATP5MC2 LTB4R BOC ORAI3 POLH XYLT2 TTLL1 DYNC2H1 KCNJ2 KCNJ6 HLTF PAPLN TRAPPC6A STX1B FDXR TMEM129 HSPB6 SMAP2 DST PDGFRB XPC NISCH LRRC32 GLT8D1 BAALC NPL PRCP SLC13A3 GNB3 IGF2R EFEMP2 STEAP2 PRSS21 INHBB RUNX1T1 GPM6B PCM1 TMEM254 TMEM119 SLC9A9 CACNA1C MAP1A CPQ LUM CTBS ABCA2 MPP2 ADH1B AEBP1 ALOX12 COL5A1 SULT1C4 HOXB4 PODN NOP53 CRTAP COL16A1 LOXL3 SELENOM GAS5 ALDH7A1 HMG20A TUBE1 LRRN3 GAMT TUB ZP3 MANBA MAP7D2 PGAP1 FAT2 RBM20 CPE FAM43A ZNF608 MAN1C1 CEP44 CEP120 ANK2 C9ORF72 CLEC11A VASH2 TTC17 ABHD14B NME3 ASMTL OLFM2 EML2 FAM155B GABPB1-AS1 TMEM134 ARL4A ZSCAN16-AS1 CUL9 SLIT2 TCTN1 EMILIN1 LDHD ACAD11 IQGAP2 HSPA12A NID2 SFMBT2 SVEP1 KCNK7 SPAG17 LRP4 ACAP2 P3H3 FMOD LOXL1 BARX2 NGFR OSR1 GARNL3 MRVI1 FRMD4A RASL12 COL15A1 CASTOR1 COL23A1 HOXB5 MIR205HG SMIM19 ZNF717 HSD11B1L RIN1 AP003396.5 LDB2 EFNB3 TBX5 AC098595.1 LYRM7 BIVM FAM171A2 MEIS3 MR1 REEP2 RCN3 PALM CNTNAP1 PIEZO2 JCAD RNF157 ACAD10 BBS1 PCDHGA12 CHN1 TCEA2 MAGED4B BNIPL ANKRD16 PTCHD4 FAM131C HOXB3 DZIP1 SCG2 DLK2 CACHD1 CLDN11 NPTXR ZNF589 TMEM42 NT5M IL20RA RHBDL1 AGBL5 CPEB1 RBM26-AS1 ZNF333 FBXO17 BDNF-AS CUL7 RCCD1 PDE8B TMEM200C MOXD1 RSPO2 CYB5D2 GPRASP2 CARMN DACH1 ADGRA2 TMEM200B NTM ANKRD24 TCAF2 ADAM33 LINC02568 POLR3GL MIR200CHG AMY1A ANGEL1 NFASC RNF150 PRELP AMZ2P1 KLHDC1 PAAF1 KATNAL2 C12ORF76 PDE7B CD164L2 C7 EMID1 RPLP0P2 GUCY1B1 AL671762.1 FAM162B AL359504.2 AC073111.4 MAFTRR PLPPR4 MTND2P28 TMEM35A AC006504.5 PPIEL AC084036.1 BACE1-AS AC092535.5 CLBA1 AC012158.1 TCAF2C CAPNS2 AP001267.1 AC090004.2 CERNA2 MT-TS1 AL356599.1 P3H4 HOXB2 MT-TY EEF1AKMT2 SNHG29 ZNF331 AZIN1-AS1 AL354718.1 AC010442.1 FAM86JP CNTN3 CCN5 LEXM AC103702.1 AC025470.2 AC005944.1 TARID EEF1AKMT3 TMEM266 AC010997.4 AL590560.2 Top 500 up genes from control vs. Ad5-hACE2 for SARS-CoV-2 infection in mouse lung from GSE158069 Mice were inoculated with Ad5-hACE2 or Ad5-empty and infected with SARS-CoV2. Associated with publication Han et al. Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection. Am J Respir Cell Mol Biol 2021 Jan;64(1):79-88. PMID: 32991819 GLA MISP BIRC3 RBL1 CCL2 CCL5 ANPEP UBD PDCD1 NMI TNF THY1 ICOS CXCL10 JAKMIP1 CXCL16 CTLA4 SARS IFNG RAB8A HMOX1 TREM2 TUBA1C CTSD STAT1 B2M PRIM1 BRCA1 CNDP2 EIF2AK2 TMEM173 CD7 RCC1 UNC5CL PLB1 CD8A YWHAH FERMT3 ISG15 CXCL9 GFER ENO1 LCP1 HIST1H4B KRT18 HIST1H2AG HIST1H2BK CKS2 HIST1H2AC CCL8 TACSTD2 ISG20 PLA2G7 KRT8 TPD52 AIF1 ITGB2 NACC1 LAIR1 C1QC PARVG C1QA LRRC25 TGFBI SH3BP2 BST2 SLAMF8 GRN HK3 GALNS SLC11A1 EXO1 GAS2L3 MILR1 CDCA8 GBGT1 TROAP C3AR1 CAPG LMNB1 TUBG1 PLBD1 CTSB GTSE1 UBE2C AREG GLRX SHCBP1 TMEM106A KIF18B NUF2 MSR1 LHFPL2 BUB1B KIF2C AURKA GPNMB IRF5 RRM2 CDK1 CTSZ BIRC5 SCIMP EPSTI1 RGS16 PRR11 CDCA2 LGALS3 TPX2 HEXB PADI2 ANLN CDCA3 BATF2 SKA1 TTK MKI67 SH3PXD2B MTHFD2 CLEC12A CD163L1 NCAPG CD247 GPR68 IL7R SH2D2A CST7 MATK RUNX3 A2M CCL4 PLCXD1 SERPINH1 MPEG1 BATF MMP25 FAM83F INPP5D IRF8 UPP1 CTSC ZMYND15 MAPK13 CENPK HCLS1 MEFV PTPN22 ZAP70 RSAD2 CD6 E2F8 GPR65 OAS3 SLC37A2 KLRC1 IDO1 IRF7 CFB PSTPIP1 CREG2 NKG7 CD3G LAX1 PGLYRP2 ZBP1 RINL AOAH RAD51 SLAMF7 IL18BP LCP2 SH2D1A GBP5 TNFRSF9 CCL1 GATM MS4A7 CTSW FAM83D PLD4 CD5 LILRB4 ACSBG1 HIST1H3D CCL20 SLC29A3 CD27 CLEC5A LCK CRTAM IL2RB CKAP2 CD3D LPXN GPR176 ARHGDIB FAM26F SPC25 HIST1H2AE MELK RAC2 CD72 CENPM TNFRSF18 TNIP3 CD3E CCR5 FYB LY9 LY86 VAV1 PREX1 GLIPR1 FCGR2B IRG1 CRMP1 TBX21 COTL1 DNASE1L3 MYO1F UBASH3A CTSS GPR171 GEN1 APOBEC1 FCER1G SYT12 PSAT1 LACC1 IFIT3 CD84 RTP4 SLC7A8 XAF1 PSMB8 CD274 GBP4 CYBB IL1RN IFIT2 IL2RA CD300LF PTAFR TNFRSF12A TIFA GBP2 GLIPR2 GBP6 TARM1 BASP1 AIM1 PARP14 SOCS1 GPR35 SAMHD1 PPA1 PARP11 UBE2L6 PLAU GBP7 WARS SP110 PSME1 PSME2 LY6E RHOG ICAM1 DTX3L IRF9 GBP3 FABP5 LITAF SH3BGRL3 IFI30 GIMAP4 TALDO1 FXYD5 CFL1 HEXA IL2RG GNS NCF4 EFHD2 MARCKSL1 RFTN1 CREB5 LST1 CCR8 NOS2 TLR9 MUC1 ZNFX1 UBE2S PRR13 S100A11 MIF CORO1C AHSA1 SNX10 SDF2L1 MALT1 HIST1H3G ANKRD1 HSD17B7 MAP2 MCM6 HIST1H3B PRF1 P2RY13 CD40 MB21D1 TRIM21 ZC3HAV1 AMICA1 WAS TNFRSF4 PACSIN1 FES BIN2 CPNE2 CXCL11 HIST1H2BL MNDA HIST1H2BG WDHD1 RHNO1 LGALS9 ACOT7 ARPC1B CSTB PROCR SH3KBP1 PIK3AP1 RNF149 CTSA ACTN1 ARPC4 PTPN6 CSF2RB CD52 GZMB ITK ACTR3 HIST1H2BF P2RY6 PPFIA4 FOLR4 SDC3 MMP2 ADAM8 CARD11 NCF1 CD68 TNFSF9 CCL12 CCL3 PRKCD CCL7 FUT7 TBXAS1 LILRB3 CD300A TNIP1 FGR FGD3 DPP9 TNFRSF1B B4GALNT4 HAUS8 BAK1 MOB3A NECAP2 OAS1A RNF181 CLCN7 CMTM7 BST1 SETD8 PDIA3 E2F4 ATP6V0A2 ACP2 NCAPH2 ABR NASP FDPS MUC4 EYA2 GALNT6 IIGP1 HIST1H2BJ FOXP3 SEMA4A ITGAE HAVCR2 TGIF1 TNC PLCG2 CYB5R4 H2-D1 UBASH3B AEN ANAPC15 PIF1 RHOF GNA15 NOL12 RFC3 LY6C2 IGTP H2-AB1 SERPINA3F GM4951 FCGR4 HIST1H2AB APOL9A HIST1H2BB GBP10 TGTP1 IFI204 TGTP2 IRGM1 OASL2 APOL9B SLFN2 SERPINA3G MS4A6C OAS1G GBP8 FCGR1 IFI205 MS4A6D HIST1H2BM FCGR3 PHF11D PHF11B SLFN8 9930111J21RIK1 SLFN1 HIST1H3I H2-DMB1 GIMAP3 HIST1H2BN HIST1H4K HIST2H2BB HIST1H2AF HIST1H2AK APOBEC3 TVP23A HIVEP3 RAB11FIP4 AI607873 CD8B1 BCL2A1A CCDC25 SPSB4 METTL21D HTR7 MINA F830016B08RIK GM12185 LY6I GBP11 SLFN10-PS G530011O06RIK GM5431 MRPS18B 1600014C10RIK SLFN9 GM4841 OLFR56 GM12250 AB124611 AW112010 2010016I18RIK BCL2A1D IL12RB2 DARC TIGIT GM11648 AF251705 A530088E08RIK D730005E14RIK PIRA7 GP49A A930024E05RIK 1300002K09RIK BCL2A1B PIRA6 PIRA2 APOL7E I830012O16RIK NLRP1B H2-Q8 1600016N20RIK AA467197 IL21 CSF2RB2 KNG2 A630089N07RIK Top 500 down genes from control vs. Ad5-hACE2 for SARS-CoV-2 infection in mouse lung from GSE158069 Mice were inoculated with Ad5-hACE2 or Ad5-empty and infected with SARS-CoV2. Associated with publication Han et al. Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection. Am J Respir Cell Mol Biol 2021 Jan;64(1):79-88. PMID: 32991819 CYP3A13 NOX4 APLNR PTBP2 OTC COL4A6 GPT FABP1 XPNPEP2 ETV1 EHBP1 F5 UGGT2 HEPH NR3C2 TLE1 ABCG2 POR F2 HERPUD1 STOM MOB2 HS6ST2 ESM1 ARHGEF12 SLC9A6 CRADD NEO1 2700046G09RIK FGFR4 ZRSR1 ALDH6A1 MYO6 FBXL3 RPS6KA5 ARL4D NBEA SLC16A9 AK4 RBPMS HS3ST1 HES1 ADCY2 SLC4A4 HLF UPK1B FMO3 LURAP1L MYRIP SNORD17 RHOBTB3 PNRC1 TRIM2 HEY1 GALNT5 TCP11L2 NDRG2 SIX4 MEIS1 TMEM109 ACSS1 STEAP3 GSN ALOX5 SULT1A1 LPL TMTC1 TMTC2 OLFML2A DPYD LTBP4 SGCD PER3 CHIC1 TPPP KANK3 ARVCF CDKN1C COLGALT2 AKAP12 IGFBP3 TGFBR3 CDS2 KLF15 PLCXD3 PKD2 KLF11 MAPT FAM84B SOX17 CLSTN1 PRICKLE1 SOX7 EDNRB NKD2 BMP3 FGF10 SLC5A8 WNT10B DIXDC1 WNT2 GABARAPL1 SOX11 SHISA2 RYK EFNB2 GPM6A PTPRU FZD7 SLC24A3 CASQ2 FABP3 CYP26B1 GRIA1 HEPACAM2 CHRDL1 AMBP HMGCS2 SLC4A5 SCUBE2 GLT8D2 EPHX1 GDF10 ANGPTL2 MYH7 TRIL LRRC17 LRAT DBP THBD TNS1 TNNC1 BMP6 UNC45B CDC42EP1 GATA2 TMEM204 CLEC14A JUN SOX18 CLDN5 RPL5 RPS19 FIGF DCN EFEMP1 NR1D2 KLF9 DDR2 GSTA3 PLXDC2 ESAM FDX1 SOD1 PIM3 AQP1 SELENBP1 CDO1 GNG11 NRP1 NOVA1 ADAMTS17 TBX3 TRPC3 CNKSR2 SLC38A4 WSCD1 ESRRG ADRA1A SNCG GLB1L2 INSR PLA2R1 SMCO4 EPDR1 L3HYPDH CTSO LDHB PPAP2A SLCO2A1 ADCY8 TOB1 TMEM47 ID1 SNORD104 FOXO4 TAF7 HOXA5 MCC BCHE TNNT1 PPM1K SLC16A12 MEDAG FGFR3 CDKN2C SNHG11 CRISPLD2 PER1 GABRA3 TMEFF2 ABAT SPIN4 NPR2 ADRB2 MECP2 TMEM159 MEIS2 CRIM1 IGF1R SEMA3G TCEAL3 ETS2 HDX CHST15 PLSCR4 IRS1 COG3 MS4A1 GPRC6A SESN1 ADAMTS5 FLRT2 CBS WFDC8 IGF2 KANK4 ENPP2 A1CF GPR21 SLC38A3 NR1D1 NKAIN4 FAM198A JPH2 ECT2L LAMC3 PRKG1 CD300LG ADAMTS8 SNORA78 CD209A RMDN1 UCHL1 TBX2 GNAQ CTSF FAIM2 LARS2 OTUD1 VTN WDSUB1 ABCB11 CSRP2 ZFP30 ZBTB10 CLDN1 RBP4 DMPK MEGF6 CHST3 SYNE2 SYNM RGS18 ARHGEF15 SPHK1 RPS6KA2 FXYD6 TUBB4A MCCC1 TRF GHR PRKCE NPR1 VAMP2 GLP1R MPDZ FAM13C AZGP1 KDM6A SLC22A3 FABP12 IMMP2L RUNX1T1 RRAS2 CBX7 TBC1D12 ABCA9 NOTCH3 CCDC85A FBXO32 CYP27A1 AQP8 LTBP1 KCNK2 SLC22A5 IMPDH1 HRG ABCA6 GJB1 C9 EDA SLC16A2 SIAH1A MAPK12 RGS6 RRM2B POLDIP2 GATA6 TEF TPD52L2 SERPINA1B CTDSPL SPIRE1 LRRN3 CNKSR3 MTSS1L ANKRD50 KLHL13 PPP1R3C VGLL3 PCDH7 ECM2 TRPC1 NTN4 GFRA1 ZC3H6 CCBE1 JMY HYAL2 PDE3A ZCCHC14 RNF103 SNORA74A PRRX1 ARL4A ARAP2 SSPN PHKA1 TTC28 SEMA3D CYP2C70 UGT2B34 C4BP CYP2D22 HDAC11 PCCB ACAA1B HBA-A2 ABCA8A CYP2C29 FGGY HOXA3 NID2 ADCY9 DPYSL5 SNORD22 PCDH19 LRP4 GALNT15 COL8A2 RASL12 ADARB1 TIE1 DES RBP1 TMEM220 IYD HOXB5 PDE4C ANKRD37 PLLP 1190002N15RIK EPN2 1110001J03RIK SNORA16A NXPE2 PTGIS ATP1A2 TECRL ANKRD63 PKIA COLQ TWSG1 PGM2L1 TMEM64 SGTB LMBRD1 PAQR7 FAM120C FUT10 FANCB OPCML RAPGEF4 GALNT13 RAPGEF5 SEMA5A AMIGO1 1810026B05RIK ARHGAP20 AAED1 CD209F KCNA2 C130074G19RIK ACSS3 PCDHAC2 RAVER2 CNTFR PCDHGB7 MYLK3 MMP16 KCNQ5 NNAT GATAD1 PTPRG PCDHGB6 NOV PHF17 FBXO17 LRCH2 MGL2 ZFP503 RAB6B ZFP704 RGS9 ZFP383 BBS9 CYP2C44 ABCA8B UGT8A UGT8A 1110020A21RIK CYP2J9 9930014A18RIK ZFP931 JAM3 LRTM2 ZFP641 FCRLS FIBIN PLAG1 TMEM255A HDGFRP3 L2HGDH RTN1 NHLRC1 KCNMB2 CAPS2 AGBL4 TLL1 GM13152 9330159F19RIK ZFP882 PRKG2 ZFP846 CNRIP1 ZFP869 EMR4 E130311K13RIK LOC106740 ZFP68 GM20594 D230025D16RIK GM872 CCRL1 6720489N17RIK PEG13 GM4788 IFLTD1 2810025M15RIK ZFP521 MUP14 GM4285 CES1G CES3A D830026I12RIK RDH7 RIAN ZFP964 1700096K18RIK CYP2F2 CCL27A GM1078 B230219D22RIK VAULTRC5 KLHL38 2810410L24RIK MUP20 GM2083 C630043F03RIK E030013I19RIK E030003E18RIK 5031426D15RIK OLFR920 KCTD12B 2410066E13RIK SNORD15B CML2 1810010H24RIK 1810014B01RIK 2010002M12RIK Top 500 up genes from SARS-CoV-2 infection in human lung from GSE150316 Autopsy samples from patients deceased due to SARS-Cov2 infection, and from negative controls, were collected for total RNA-seq analysis to assess viral load and immune response. Associated with the publication Desai et al. Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection. Nat Commun 2020 Dec 9;11(1):6319. PMID: 33298930 PF4 HIST1H4A PRIM1 ICAM3 TPSB2 RPL24P4 PALM2-AKAP2 PIP IGKV2D-28 IGHV2-5 IGHV3-7 IGHV6-1 IGHJ2 IGLV3-10 IGKV1-12 CHRFAM7A IGHV4-59 IGHV3-64 IGKV1-33 IGHV3-74 IGLV3-25 IGKV2-28 IGLV3-1 IGHJ3 CPA3 RNU1-3 RNU1-27P RN7SL262P CBLC SKAP1 FAM26F CCL17 GPR141 CCM2L CAMK1 KLRC2 PLGRKT TMEM14A C2ORF74 HIST1H2BE KRBA2 DEXI ARHGDIG CYTL1 STAP1 GRP HIST1H4D C2ORF76 HIST1H2AM APOBEC3B SCT BTC HIST1H2BF NCF1B WDSUB1 GLUD1P3 FAM3D GOLGA2P7 RHEBP2 TXNRD3 AS3MT HORMAD1 PDF RPS15AP10 NEDD8-MDP1 CD24P4 TMSB4XP8 SRP9P1 C1GALT1C1 SYNJ2BP-COX16 GSTT2 HIST1H4J GRAP HIST1H4K ZMYM6NB LINC01057 PLA2G10 SCARNA20 RTCA-AS1 ZFY C4ORF48 POLR2I GOLGA8O POMZP3 CHKB-CPT1B ZNF625-ZNF20 AL592183.1 BEX5 CTAGE4 ZNF781 SPIN2B HIATL2 GATSL2 IGKJ5 TSTD3 PEX7 HIST2H2AA4 HIST1H4L SNHG21 PLA2G1B MEF2BNB-MEF2B MORN2 CEACAM4 MT-TS1 RNU6-107P RP11-297C4.2 RP11-851M3.1 CTD-2313J17.1 RPL37P6 RP11-504P24.2 AC016644.1 RP11-69L16.4 RP11-262H14.11 RP11-638I2.9 RNU6-560P RP11-470B22.1 RP11-14I17.2 RN7SL850P C8ORF44-SGK3 LINC00891 RP11-685M7.5 CTD-2363C16.2 RP4-591B8.2 LINC00278 RP1-228H13.2 RP11-326C3.7 AC011513.3 RWDD4P2 LINC01031 IGLVI-70 PSMA6P1 AC004967.7 AC004381.7 AC025918.2 RP11-793H13.8 RP11-204M4.2 RP11-619I22.1 RP11-124N14.3 RP4-669L17.8 RP11-661A12.9 TBC1D3L RP11-111J6.2 CYCSP23 RP11-428C19.5 AC002066.1 RNU4ATAC16P RNU6-576P RNU6ATAC38P CCNB1IP1P3 RP11-370B11.3 MIR1254-1 RP11-253A20.1 CTB-83J4.1 RP11-261C10.4 RP11-43P8.2 RP11-384C4.7 TMEM5-AS1 RP11-632C17__A.1 RP11-27M5.1 RP11-93O14.3 RPS20P15 AC012487.2 CTA-276F8.2 RP11-930O11.2 TMSB4XP1 RP11-631M6.2 RPS26P3 RP11-449H3.3 SNORD114-14 RNU11-2P PMS2L2 RP11-403P17.5 SVILP1 RNY4P25 AL449212.1 RNU4ATAC11P ZNF839P1 PIK3IP1-AS1 SNORD14A RP11-537A6.9 FERP1 RP11-144G6.12 RP11-21L19.1 CH17-360D5.2 CTB-193M12.3 RP11-474P2.4 TYMSOS AC009299.5 TMEM92-AS1 RP11-75C10.7 RP11-14D22.2 MROH7-TTC4 RP11-710F7.2 U5 TRGV10 AC090587.4 RP11-727F15.11 C1DP1 RP11-632F7.3 RP11-110G21.2 IGHV1OR15-1 RP11-613C6.2 ULK4P2 RP11-114N19.3 RNA5SP508 RP11-208G20.3 RP11-89N17.1 RP11-463D19.1 SNORD116-14 GUSBP11 RP11-549L6.3 RP11-245J9.6 RNU6-608P RP11-760H22.2 RNU4-47P STARD13-IT1 RP11-212P7.1 RP5-1021I20.4 GUSBP9 CTD-2647L4.1 AC005614.5 RP11-182J1.12 SNORD11 LL22NC03-80A10.6 CYCSP10 RNU6-767P RP11-522L3.6 TVP23CP2 RP3-468K18.6 RNU6-638P AC132812.1 CTD-2313J17.6 RP11-112J3.16 ZFY-AS1 RP1-30M3.6 RP11-666A8.7 RP11-301A5.2 CTC-453G23.8 RP11-473O4.4 EIF4E2P1 CTD-2370N5.3 SNORA2A RP11-295I5.4 RP11-128N14.5 CTD-3116E22.6 RP11-632K20.2 RP11-164H5.1 RP11-508N12.4 ABHD11-AS1 AF111168.2 RP11-166N17.3 RP11-187C18.3 RP11-848G14.2 RP11-1123I8.1 RP11-160E2.6 RP11-347C12.1 RP11-48G14.3 RP11-452I5.2 AC097382.1 RNU6-1188P RNU6-842P RP11-346M5.1 RPS20P4 RP11-843A23.1 AC006160.5 AC093732.1 ITGB1P1 RP11-52B19.1 MIR548AA1 CTA-384D8.34 RNU6-5P RP11-278J6.5 RP11-13J12.2 RP11-157P1.4 RNU2-25P RP5-1042K10.14 CTD-2593A12.2 RP11-133N21.10 CTD-2235C13.1 RP5-875H18.10 RP11-266K22.2 SNORD116-29 RNU6-199P MIR650 CTD-3195I5.3 XXBAC-BPG248L24.12 LLNLR-307A6.1 RP4-613B23.1 RP11-394B2.6 RP11-488L18.8 AC007283.4 DDX3P2 SNX29P1 RP11-235E17.5 RP11-530C5.2 RP11-700F16.3 ERCC6-PGBD3 TRAV24 RP11-146D12.2 RP11-357G3.1 RP11-73M18.7 RP11-603B24.2 CBX5P1 SNORA50 CH17-472G23.1 RNU4-75P SNOU2_19 RP11-49I11.4 LA16C-306A4.1 RP11-420A21.1 RP11-779O18.1 AC007969.5 RNA5SP179 CTD-2574D22.6 AC007875.2 HSPE1P13 RP11-188P20.3 RP11-110H1.4 CTD-2595P9.2 RP11-530C5.1 RP11-147L13.12 AC141272.1 RP13-395E19.3 AC004593.3 C8ORF87 AF224669.3 RP11-169K17.3 RP11-275I14.4 AC025442.3 RP11-57H14.2 SNRPGP4 CTD-2583A14.10 AC093388.3 MPRIPP1 AC114730.2 RP11-562A8.1 AC006946.12 RP11-146F11.5 RP11-132A1.4 RP11-98J23.2 YWHAZP3 RP11-216M21.1 RP11-40C11.2 RNU1-72P RP11-667M19.4 RP11-438N5.4 HMGB1P19 RN7SKP36 RP11-1348G14.8 RP11-663N22.1 BANF1P4 RP11-395B7.4 RP11-1252D15.1 RP11-203I2.1 CTD-3157E16.1 RP13-131K19.6 GNA14-AS1 RP11-244H3.4 RP11-599J14.2 CTD-2024I7.1 RNU4-45P RP11-731D1.1 UBE2V1P1 RP11-1060J15.3 IGHV1-3 RP11-411B6.6 CTB-5E10.3 RP11-544M22.13 RP11-155G14.6 AC108479.3 RP1-69D17.4 RP11-690I21.1 MTX1P1 RP11-585F1.2 NPIPP1 CTC-273B12.5 RP11-800A3.7 RP11-626H12.1 RP1-30M3.5 RP11-325K4.3 RN7SL589P UBXN7-AS1 RP11-459F6.3 AC004754.3 SNORD62B RP11-578F21.2 AC018693.6 PMS2P1 RP5-827C21.1 SNORA76 AC097635.4 AC015688.3 BX842568.4 RP11-208G20.2 RP11-163E9.2 RPS12P5 SNORD116-4 CTD-2544H17.1 RP11-561C5.4 CH17-431G21.1 CTD-2349P21.12 SNORD14E RP11-73M18.10 AC006042.6 RNA5SP518 AP000223.42 AC011530.4 AC061992.1 AC018738.2 RP11-864I4.3 RP11-1212A22.4 CSNK2A3 RP11-770J1.5 RPS26P47 RP5-855D21.2 PRH2 MTAPP1 FAM92A1P1 RP11-56B16.5 RP11-152C15.1 RP11-462G2.1 MIR4441 CTD-2207P18.1 CTD-2287O16.1 SNORD114-3 AF011889.2 AC099850.1 RP11-71E19.1 RP11-358D17.1 RP11-529F4.1 RP4-575N6.4 CTB-40H15.4 IGLJ2 RN7SL275P RNU6-33P RNU4-9P NSFP1 RP11-327L3.3 RP11-22B23.1 RP5-973N23.4 CTD-2538G9.5 RP11-488C13.6 RP11-702L15.4 RNU6-60P SNORD127 XCL2 RP11-506M13.3 RP11-3P17.5 RP1-134O19.3 ZMYM4-AS1 BP-2189O9.2 FAM133DP RP11-30L3.2 CTD-2081C10.5 RP11-654A16.3 RNU6-884P RP1-41C23.4 RNU6-942P SNORD115-32 CTB-58E17.9 RP11-298I3.3 RN7SL622P CTB-129O4.1 RP11-298E2.2 RN7SKP150 CTC-471J1.8 FAHD2CP CTC-338M12.5 AL627171.2 SNORA70G RP11-111F5.5 CTC-518P12.6 ZNF849P AC005546.2 RP11-535M15.1 RP11-49K24.9 HIST2H2BC AC002398.12 RP11-174N3.4 HLA-U RP11-822E23.8 RP11-379B18.1 RP11-574K11.5 AC006077.3 RN7SL78P CTC-490G23.2 AF178030.2 TBC1D3E RP4-539M6.21 RP3-415N12.1 RP11-87N3.6 RPS23P6 RNU6-1338P RP11-413E1.4 RP11-499O7.7 RP11-671M22.4 RP11-575A19.2 RP4-751H13.5 STEAP2-AS1 RP11-333J10.2 Top 500 down genes from SARS-CoV-2 infection in human lung from GSE150316 Autopsy samples from patients deceased due to SARS-Cov2 infection, and from negative controls, were collected for total RNA-seq analysis to assess viral load and immune response. Associated with the publication Desai et al. Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection. Nat Commun 2020 Dec 9;11(1):6319. PMID: 33298930 UHRF1 CYP4F12 SH3BGR KPNA2 HSD11B2 FBXL12 LRRC66 POLA1 IL4 BTNL8 NAGS ACTRT1 BTNL2 MUC17 NUP85 GFER CYP2F1 ATP12A RPL13AP5 SRD5A1 OCRL FAM72A TBC1D2 KLF3-AS1 NCALD PHOSPHO1 PTK6 GJB5 NKD2 WDR37 ACTR3P2 OR2G2 FAM9A OOSP2 MCM5 KCNJ3 VAT1L MICALCL CELF5 TMEM260 FXYD1 ART4 KIRREL3-AS3 ALX4 HILS1 ZNF841 HOXB8 TXNDC17 RABAC1 COPRS RNF151 TRMT11 TMEM50A ZP1 ID1 DLG4 ELMOD1 LINGO1 WT1 MYOZ1 ZSWIM2 XRCC1 LBR DDX25 OTUD6B GOLGA6A TSPY26P LRRC4C FAM111B REEP4 LINGO2 GRIN3A SLC26A7 OR52A1 WFIKKN2 AMPD1 VPREB1 OR8D1 TACR1 HPD CEP85 PRR21 CR2 REXO1 IKBKE SNRPD3 MYCN ARF5 STX4 SYN3 IL37 SUV39H2 SCNN1D ZNF324B DGCR9 C20ORF203 UTP6 RPS6KA4 ZFYVE9 SLC17A1 GABPA RFX6 G6PC2 ZBTB18 OACYLP GALNTL5 ZNF396 OR4C45 LILRA2 NPAS4 ZNF720 KCNK10 KCNK2 ZRANB1 UGT1A4 GPLD1 SLC27A5 OR4K17 MIR34A ILKAP RCSD1 HNMT SLC39A6 AC141586.5 SRFBP1 GNA15 PARD6G KIF5C FAM149B1 CXXC1 MTMR12 SETD1A MTX3 PCDHGB5 HNRNPA1P33 ATPAF2 CAMK2B ZNF561 C17ORF104 HOXA4 NPAT HAPLN1 SYNDIG1L S100A1 GTPBP8 MOSPD2 DHX8 ARHGAP11B KLC3 FBXO15 CCDC27 TOMM40L HMSD GPATCH2 TLE6 FAM76A BBS9 TRPM1 TRPM1 CRIP3 APCDD1L PAAF1 ABHD6 CLPSL1 SLC35D2 CXORF23 C20ORF195 AC009299.4 ELMO1-AS1 RP11-14J7.6 OR7E25P CTAGE16P RP11-552M6.1 RP11-687F6.5 PPCDC TDH RP11-153F1.2 RP11-94H18.1 ZDHHC20P1 CHRM4 TOX4P1 MTIF3 AC007106.1 THRB-AS1 RP11-529G21.3 LINC01572 ST6GAL2 RP5-1046G13.2 MTND1P11 RP11-293B7.1 RP11-131K5.2 CTD-2588J6.1 NDUFA5P4 RP11-96J19.4 RP11-253D19.2 RP5-827C21.4 RP11-583F24.3 RP11-474J18.1 GVINP1 HYMAI LINC00505 PKMP5 RP11-96C21.2 RP11-81A1.8 RP11-312A15.1 RP11-106J23.1 DUSP8P3 CTC-339O9.1 RP1-137K2.2 CCT6P4 PIWIL4 MEOX2-AS1 LINC01165 LINC01451 ATP6V0E1P2 AC017081.2 RP11-143M1.3 SUMO2P4 AC007405.4 RP4-806M20.4 TMEM196 RP11-451F14.1 PIGFP3 TUBB8P5 HAUS6P3 RP11-579O24.3 RP5-821D11.7 OR5AQ1P RP11-213G2.5 SALL4P2 RP11-1258F18.1 KRT37 RP11-467P9.1 RPL3P3 RP11-157F20.3 LINC01372 RP11-553L6.5 PHACTR2P1 MRPL57P6 RP11-177B4.2 AC092570.1 RP11-716O23.1 RP11-298I3.4 XXYAC-YM21GA2.7 RPL5P19 RP11-284A20.2 ALS2CR11 RP11-497G19.7 RP11-264E20.1 RP11-546B8.6 AP001464.4 AC068492.1 AC010731.4 PIGQP1 OR8A1 CTD-2061E19.1 VN1R51P RP4-620E11.5 SLC25A5P2 MIR3180-4 TET1P1 PHOX2A GLDCP1 FP325317.1 RP11-343J3.5 ZC3H11B RP11-763E3.1 GPR119 AC005336.5 RP11-524O1.4 AC016907.3 AC104809.4 RP11-386D6.1 CEACAMP6 BOK-AS1 RP11-805F19.3 RP11-749H20.2 CTD-3187F8.12 AC106869.2 DAND5 RP11-356K23.1 AC012358.8 AC096574.5 HNRNPA1P73 CCAT2 AC009303.3 CTB-99A3.1 KRTAP13-5P RP11-401P9.6 RP11-360A18.1 KRT8P34 AC007126.1 RP11-129H15.3 AC005614.3 AC002064.5 RP11-26O3.1 RP11-202A13.1 RP11-354O24.1 TRBV7-6 NHLH1 RP11-567C20.2 AC006538.1 RP11-583F24.6 RP11-442N1.1 RP11-78O7.2 RP11-574K11.26 GOLGA2P11 ZNF90P2 LINC01221 LL22NC03-27C5.1 LINC01541 RPL7L1P3 MESTP4 HNRNPCL2 WASF3-AS1 PIN1P1 KRTDAP RP11-1O7.1 MIR7515HG FAM159B API5P2 LL22NC03-23C6.12 BECN1P1 WWP1P1 RP3-412A9.17 MARK2P10 PTPRD-AS2 CTD-3162L10.5 RP11-184D12.1 RP11-172C16.4 HOXD-AS2 RP11-218M11.7 RBBP4P1 RP11-427E4.1 AC009960.3 RP11-164C12.1 SATB2-AS1 RP11-488I20.4 RP11-753A21.1 RP11-304C12.4 RP11-146G7.2 CYB5AP5 AC020983.5 RP5-915N17.3 SETP20 CCT8L1P OR4C5 SEC13P1 NPM1P29 LAMP5-AS1 RP11-559N14.6 RP11-109G23.3 SPIDR RP11-480G7.2 PA2G4P2 DPP10-AS3 MFRP ADARB2-AS1 MTRNR2L11 RP11-287F9.1 ZNF192P1 PDX1-AS1 RP11-604N13.1 LINC01474 OPCML-IT1 RP11-475J5.4 RP11-446F3.2 RP11-617J18.1 RP11-61L19.1 ACTN1-AS1 RP11-334N17.1 CTD-2323K18.2 AC004069.1 AF230666.2 CTC-493L21.1 RP1-65P5.5 ACTR3P3 RP11-504P24.3 CTD-2619J13.14 RP11-923I11.4 RP11-76N22.1 LINC01338 DDX11L16 C8ORF86 RP11-466L17.1 KB-176G8.1 AC006427.2 RCC2P4 RP13-463N16.6 CCDC70 PCDH8P1 OR7E108P RP11-248G5.9 RP11-1348G14.4 ASZ1 RP11-432J24.3 KRT18P14 RP11-173L6.1 CYP26C1 AC004988.1 LL22NC03-121E8.4 CTD-2619J13.9 OR6C7P AC026202.5 RP11-297P16.3 SDCCAG3P1 RP11-104H15.10 RP11-8J23.1 RP5-1024C24.1 LINC00460 RFPL4AP1 CBWD7 RP11-963H4.6 OR7E12P MAPT-IT1 RP11-28P17.3 CTC-327F10.1 RP1-272E8.2 RP11-554L12.1 CTC-573N18.1 RP11-173P15.10 AC097374.2 RP11-402J6.1 RP11-719L21.1 OR2T27 RP11-439H8.4 RP11-318A15.2 RP11-388G22.1 FBXO47 RP3-461F17.2 RP11-697E23.1 KRT18P41 AC012314.20 RP11-258O13.1 AC091801.1 LRRC37A5P XX-CR54.1 RP11-182J1.5 METTL21EP HNRNPA3P15 RP11-388C12.1 RP11-81A1.7 RP11-528N21.1 RP11-332H21.2 RP5-1185I7.1 RP1-80N2.4 RP11-359E19.2 RP11-109A6.2 RP11-876N24.1 NEBL-AS1 RP11-365D9.1 KB-1000E4.2 SNORA66 PASD1 ZNF790-AS1 RP5-1041C10.3 ENPP7P2 MAPRE1P3 RP11-257P3.3 PRSS46 RPL29P24 EIF2B5-IT1 CEP164P1 AC007740.1 UHRF2P1 LINC01400 AC007682.1 KRT16P6 RP4-814D15.2 AC072062.3 CTD-2006C1.2 RPSAP4 ACTN4P1 RP11-263G22.1 RP11-694D5.1 ETNPPL AC012175.1 RP11-302I18.1 RPL12P8 RP5-1177M21.1 AC007750.5 METTL2A RP11-380D23.1 AP000477.3 ADIPOQ-AS1 RP11-106M3.1 GOLGA6L7P OR1AB1P RPL7P29 RP11-867G23.13 RP11-27K13.3 RP11-305P22.9 SDHCP3 TACC1P1 PAPPA-AS2 RNY4P10 OR5J2 RP11-288E14.2 RN7SKP186 RP11-266O15.4 AC010468.2 Top 500 up genes for COVID-19 ARDs vs. non-COVID-19 ARDs for human trachea from GSE163426 RNASeq from tracheal aspirates in COVID-19 ARDS patients compared with non-COVID-19 ARDS. TICAM2 SLC10A2 CMA1 FRMD7 PRAP1 IL17A TAAR1 SAXO1 ICOS CKM SSX7 VPREB3 IFNG SPTBN5 PLCB3 AOC1 BTNL2 TMPRSS11D GRK7 UTS2 KCNJ13 ZNF503 FAM72B CXCL9 KDR MUC21 C1ORF21 FAM117B FDCSP CD180 SHOC1 SPRR1A TMPRSS11B SPATA20 KCNK13 HCCS RGS16 CLEC12B SH2D1B ZFPM1 PTGDR2 ANGPTL6 SPON1 ZNF184 ELANE CTSG GPR87 FZD1 SFRP4 GSDME DKK2 IPO9 CCN4 OR10V1 FAM236A OR56B4 UGT2A2 OR1L6 CLCN5 KRT86 CENPA CXCR6 ULBP1 TKTL1 SLAMF9 CCL24 MYBPC3 NPPA PGAM2 CLEC6A CALML5 CNGB3 SYT10 XRCC3 HCRT PDYN LYPD8 CCL19 LGALS12 CTHRC1 NAP1L5 VSTM2A ACTC1 COX6A2 CLIC3 C16ORF90 PSKH1 MYLPF C1ORF54 SSX2 IL17F CGB1 CCL27 PIK3R6 SLC12A1 ASCL2 COL13A1 EDN2 FAM209B MAGEB10 SLC22A14 CCM2L ODF3 OLFM4 SULT1E1 LYPD4 KBTBD8 MRC2 HTR2B CDKN2AIP VASN OR2T5 TEX38 SLC25A27 APOM CYB561D2 PTTG1 C1ORF74 RNF151 NKRF TLDC2 DUSP21 LRRC3 KCND1 AOC2 RRAGB RNF25 TIFAB RPIA CEMIP CLEC3B TOMM20L P2RY14 HLA-G SLC10A1 ADRB3 APOBEC2 MARS2 C4ORF45 C19ORF71 FCRLA ZCCHC18 TSPAN33 GIMAP1-GIMAP5 INSL5 PLET1 RAB44 HSPB9 NID1 SYPL2 PTGR2 TMEM132D GOLGA8H TESK2 ISL2 CD1B HIGD1B PET117 TFPI2 C10ORF99 REC114 DCST2 CCIN HDX FUT4 ZBTB33 PTGS1 DEFA4 AZU1 LAIR2 KLRF1 TAS2R60 RIMBP3 CHST2 SERPIND1 LIMS3 ITLN1 SEMA7A AANAT SSTR3 LSMEM2 OLFML3 DNAJC5G PAMR1 TNFRSF10D GPR21 FCER1A CDH19 CRLF2 CHRND GPRC5D OR52K2 MMP24 LMAN1L GPR3 TMEM72 NPBWR2 GPR52 PCDHGC5 DDN KCNH4 ELFN1 CSNK1A1L GATA1 RANGRF SHBG TBP TNFSF11 HSFX3 PDCD1LG2 IL26 COQ2 MTRNR2L3 C17ORF113 RPL17-C18ORF32 TGM3 SLC46A2 TIGD6 ZNF41 LIN37 CAMKK1 CEMP1 GGN P2RY2 NLGN3 SH2D5 MBIP HLA-DOB MCCD1 OCLN TNNI3K SLC5A3 ZBED4 CELA2A PRAC1 SLC2A12 GABRR2 DRICH1 TMEM144 TAS2R43 CIP2A GRPR BNIP1 ATG4C ZFYVE1 SPATC1 FAM71A OR10P1 SPDYE6 RHD NANP CD1C ASIC3 CCL21 ZNF449 ZNF182 RSC1A1 TMPPE TAS2R30 TNFSF18 CLEC9A ACMSD PLA2G12B B3GAT2 SERPINA11 SAA4 NODAL SLC18A2 SLC23A2 CCN1 NHEJ1 GCSAM MTFP1 ZBTB5 UCN ARSH GPC4 TBC1D22B IZUMO4 HHIPL1 GJB4 FAHD2A LOXL4 ANKRD50 CD109 KIAA0319 SACS AGAP6 ZNF275 EIF3CL TENT4B H2AC12 NDUFC2-KCTD14 H2AC7 PPP4R4 SYT11 H2AC15 FAM168A ZNF555 GOLGA7B B3GALT2 AVPR2 PDXP HIVEP3 TAF9B LYSMD4 DOLK TIMM22 PRKCQ BNIP5 ASPHD2 NPIPB9 MSS51 GPR22 ALG10 HTR7 TSSK3 WASF3 PRPH2 MS4A14 XKR7 KCNS1 PGAM4 ARPC4-TTLL3 SEBOX F8A3 LIPK TOE1 SPDYE2B ISY1-RAB43 PPIAL4E NUTM2F BTBD18 MAP1LC3B2 TNFSF12-TNFSF13 NME1-NME2 CHURC1-FNTB HSPE1-MOB4 NBPF12 TMEM81 MIP FAM156B OXGR1 ANKHD1-EIF4EBP3 ZNF844 GOLGA8T UTP14C PPAN-P2RY11 SOGA3 CDK3 PTGES3L-AARSD1 CKLF-CMTM1 NNAT CCDC169-SOHLH2 TMEM249 DCAF4L1 SPDYE5 ERVFRD-1 LY75-CD302 IPPK SPDYE11 FOXD4 ANKRD61 STUM GDF7 DCSTAMP INSC INSC LDHAL6B ASB14 TRERF1 AMY1C TMEM102 LRRC55 SIK1B KCTD4 GRIK1 KLRC3 DEFA1 DCLRE1B KTI12 TSPO2 LRRC24 SERINC4 MTMR8 RLBP1 CIB3 DPRX PDIA2 ARRDC5 FAM184B CAPNS2 CNRIP1 ST6GAL2 PIWIL4 G6PC1 OR5B21 TMEM210 FMC1-LUC7L2 OVOL3 RIOX1 TMEM272 H3-5 OR4E1 OR52M1 CTXND2 C12ORF71 MAGEA10 GPR42 SMR3A SEC14L6 GET1-SH3BGR PIGY OR2B2 RHCE GPHA2 P2RY4 B3GLCT GCNA SMIM38 KCNE5 PCDHB15 LLCFC1 IL22 ABCF2-H2BE1 RTL5 C6ORF163 OR2T35 ARMH2 POLR1H STARD6 DEFA1B ATP6V1FNB C22ORF31 MSANTD5 TBC1D3G CFC1B PEDS1-UBE2V1 ATP1B4 NUDT11 DDX53 CORO7-PAM16 URGCP-MRPS24 IL3 TMEM89 RPA4 OR2AE1 H3C3 OR52N5 H2AB2 SLC36A3 ANKRD34B SHLD3 MPC1L C17ORF64 HPCA BEND2 PPIAL4H LIMS4 IQCF2 C11ORF42 TAS2R19 PPIAL4F HSFY1 CDY2A C3ORF84 C4ORF50 NT5C1B-RDH14 LOC102723996 CT45A7 LRRC74A ZNF878 RD3L DUS4L-BCAP29 FSCN3 TCL1B ARPIN-AP3S2 SETSIP FAM243A SPDYE4 ZPBP2 LY6G6C SLC5A4 NUPR2 CLPS MCF2 PGA5 TIAF1 USP17L15 VSTM1 TOMT H1-6 TPTEP2-CSNK1E DPPA5 OR5K2 MSMP SPDYE8 OR4C46 OR2T4 TEX55 R3HDML Top 500 down genes for COVID-19 ARDs vs. non-COVID-19 ARDs for human trachea from GSE163426 RNASeq from tracheal aspirates in COVID-19 ARDS patients compared with non-COVID-19 ARDS. AMACR MISP SLC25A21 MOGS COL4A5 SLC26A6 SMIM24 ACAD9 SLC22A9 YIF1A SCN2B SLC30A9 GPA33 ADA FAM162A HNF4A AGPS PMPCA SFN EPS8L2 INTS4 PHB FAM221B ZNF318 ANO6 THOP1 SLC25A39 TMED4 PITPNC1 AFAP1L1 NDUFV1 EXOSC4 ZNF253 OLFML2B FBXO36 COBL KIF21A CRYM GATAD2B CA8 MAP6 C4ORF19 EXPH5 GPRC5A ZC3HAV1L DDOST ZNF316 PLCB2 SRPRA EMILIN2 APOL2 GAS2L3 C14ORF119 NEK2 NOL3 JPH4 WFDC1 UACA NIBAN2 CARD6 SMTN ADAMTS2 PRR11 EPHB2 TEX2 TRIP13 NRIP1 NCAPG ZNF574 SIGIRR FGFRL1 MGAT4A ADGRB2 CRYBG2 MSC COL6A2 LIM2 ZNF540 RUNX2 ABCF3 CKS1B EHHADH ZBTB42 SULT2B1 APPBP2 MROH1 IL20RB MRO FZD3 CLSTN1 DLX2 DIXDC1 ELP3 HLA-DRB5 EFNB2 KRT13 CBFB CATSPER1 WDR5 SOX12 TPP2 MS4A6E CCDC85C ZNF862 SAA1 CD226 CCNA1 RAD54B RINL RASAL3 BRIP1 CKAP2 FSBP MELK GLIPR1 CENPE RYR2 DOC2B DHX58 KIF18A LGMN GNAL PARP9 IL4I1 PARP11 IL24 GSTM5 FGD5 BGN POLDIP3 PDE5A PFDN6 LAPTM4A DHX15 PSMB4 FUCA1 MXD4 TCP11 RNASE6 ZNF692 CD36 HPS4 PPIC SCAND1 ARRDC4 DCD GSTA2 CELF2 GPR61 KIAA0408 PPFIA3 PCBD2 CALB2 RRM1 SRM MTX2 WDR12 SDHAF2 APEX1 PDHB SUCLG2 ZFAND2A WBP11 ADORA2B VGF TNFSF15 KRBA2 PLCH2 MSMO1 BLOC1S4 REEP1 SIK1 PRRT2 CTF1 SUPV3L1 GDAP1 NNMT POLR3H MYO15A PCED1B CYTL1 CELF3 IL15 C10ORF53 CCR6 ADPRHL1 BATF3 CCNB1IP1 TXK THAP9 PSG7 VPS41 LONRF2 ASRGL1 TIA1 C12ORF60 PCYOX1 EIF5B CRIM1 SIKE1 ACOT7 CHUK FAM110C COA7 TCEAL3 GPT2 PMM1 ERAP2 MVB12A U2AF1 UQCRFS1 ILK CDA ZSCAN31 BMF PDK1 LONRF1 TRIM16L ANAPC2 FRG2 DPYSL3 ZNF676 CADPS ECT2L MEIOB TGFB3 CCDC62 HS3ST3B1 RARRES1 GFI1B DHX36 CCL7 STN1 POLR2H ZNF655 UBE2J1 ARL2 PAX1 SF3B6 ELL COX20 PEX19 RYR3 NTAN1 NNT COPS6 ACAA2 DEGS1 HRNR TBC1D17 TINF2 CCS NIP7 C9ORF64 RPF1 AKAP10 MEF2D KCNC4 FAT1 APC2 TAF1C METRN MPC1 DAPP1 ARHGEF7 SLC38A5 DKK3 VPS54 SUN1 KAT5 LZTR1 SIVA1 UCK2 TNIP2 ABHD17C RAET1G TRIP4 SH3YL1 TMPRSS6 OTUD5 CYP11A1 ADRB1 MTHFR SLC1A6 GDNF PIAS4 ADCY10 TBPL2 CRISPLD1 SLC44A4 SLC37A1 GCNT1 DNMT3A FSIP1 EIF5A2 DYRK2 ARSA MRPS15 MRPL40 ZNF169 ZNF26 HACD4 GIT2 GCSH GPLD1 ACSM5 SLC22A10 SGPP1 PARP2 ILKAP FZR1 CDK7 ZNF282 TMEM14C OGFRL1 HIBADH PALMD TIMMDC1 DARS2 F11R CNOT4 PSG4 KDM5C LPIN2 GPATCH2L RBM14 MPV17L MRPS21 S100A7 B4GALNT2 ACVR1 UBN2 PCDH7 DENND4C LPCAT3 SBF2 PYROXD1 TMX3 HCFC1 NOC4L TMEM53 WDR62 NR2F6 DDIAS ZNF148 PDE10A MRFAP1L1 PM20D2 PDPR RAB27B WAPL SLC26A9 IDH3G ZNF778 GPATCH8 ZMIZ2 LMF2 PHYH KLHL28 PIAS2 H4C2 ARL4A ZNF428 DYNC2I2 KLHL36 C1GALT1C1 BCAP29 TTC28 RANBP3L PSMD12 HDAC11 CROT PRXL2C DOCK10 ESYT1 HNRNPH3 PHKB SGCB TVP23A NAXE MSTO1 AGPAT1 MTERF1 LRP4 WDR19 SLC4A3 TMEM63C ATAD3B DPH3 MCM8 MRPL10 SLC25A12 CLOCK UTP14A RHAG EIF1AX RNF38 TMEM222 CARS1 PSMG3 NOB1 JPT2 LIX1L EFNB3 FITM1 SMTNL2 MED7 ZNF71 ZFPL1 CHGB SLC44A1 KLHL22 DNAJC30 DZIP1L EIF2S2 FBXL14 GPR85 DPP10 CEP41 EVI5L HTRA3 SLC17A7 RNF157 RUFY3 VPS33B B3GAT3 MEAF6 GTPBP8 NELFCD KIFBP ZNF786 SRCIN1 NPHP4 RIF1 SERF1A SCRG1 DUSP19 SNTB2 SETD6 MIEF2 DCLK2 RNF103-CHMP3 TTLL3 NOL4L NPTXR SCN4B USP30 FBXO17 MRE11 TLE6 MARF1 HTRA4 CUZD1 WRAP73 CCHCR1 KHDC4 PEX11A KANK1 SEZ6 ATRIP ZNF684 EFHC2 NME9 WDR93 PLA2G1B LYSMD1 INTS9 FBXO48 AHI1 ZNF311 MON1B TRIM68 C9ORF153 ANKRD35 NHLRC1 RHBDL2 C10ORF67 ARHGAP40 DPP6 TPRX1 IGFL3 FAM240A ERCC8 TMEM244 GJD4 GAGE10 POTEC C8ORF89 GRIA2 STPG4 NPIPA3 LOC730098 OR2B11 CNPY4 TEX45 SPAAR CEP162 FAM124A ENTR1 H2AB1 Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 2 from GSE162208 Bulk RNA-sequencing was performed on blood of SARS-CoV-2-infected hamsters at 2 days post-infection with SARS-CoV-2. MAPK3 CCL2 TRIM59 NMI DDX58 TBK1 UBE2D3 TRIM15 NGDN PGLYRP4 TOR1AIP1 RAB8A GRIPAP1 STAT1 BTNL2 TRIM25 B2M EIF2AK2 TMEM173 ISG15 SRC LNPEP MX1 MYD88 LRRC1 SFXN5 ZC3H12C VLDLR MCL1 TNFSF10 CEBPD STEAP4 CCL8 ESRP1 ISG20 TMIGD3 DHRS9 ARID5B UNC93B1 LSP1 ACER3 PARP10 TOR1B RNASEL GRINA ALOX5 BSDC1 SLC15A3 HK3 MYOF PLEKHN1 SAP30 LMNB1 SLC35A5 RAB20 GLRX NEK2 IFI44 ADAP2 METTL9 EPSTI1 TRPM2 LTA4H RASGEF1B CXCR2 ANGPTL6 CCL4 SLC2A6 PHOSPHO1 B4GALT5 CDKN1A SLC2A3 MMP25 AGRN CARD14 IBSP DCK FOCAD OSBPL1A MAFK PWWP2B ACPP HELZ2 OGFR MAPK13 RSAD2 IL10RA IRF7 ZBP1 NLRC5 LCP2 GBP5 TAP1 TLR1 HCST TACC3 FAM26F SLAMF9 CCR5 HMGB2 FYB CLEC7A NDC80 LAG3 APOBEC1 FCER1G OAS2 SIGLEC1 PSMB8 CD274 APOL6 CCR1 DHX58 FBXO39 IL1RN TREX1 CMPK2 IFIT2 EVI2A CLEC4E CD177 HERC6 NPRL3 MLKL STAT2 PML TCIRG1 SOCS3 ADAR NAMPT GBP2 NT5C3A PARP9 PARP12 HSH2D NFIL3 XDH NOD2 IFI35 SOCS1 ARG1 C5AR1 BTBD17 MITD1 UBE2L6 UBA7 GBP7 IRF2 PSME1 TMCC2 ATP6V0C DTX3L IRF9 PSMB9 GNG10 LAMP2 CTSH GABARAP RNF114 TAPBP ARRDC3 TP53INP1 TYROBP ATF4 ACTA1 IL2RG UBE2V1 RNASE6 LRG1 THEMIS2 SAT1 FPR2 SAMSN1 LST1 TLR6 TNFAIP3 AICDA TNFRSF14 TIPARP CSRNP1 ZNFX1 PFKFB3 PRR13 WBP2 CHMP5 BFAR STK39 VMP1 MICU2 EMC9 GNA13 MXD1 PTBP3 TLDC2 PURB CREBRF HMGCR ANKRD13A CD46 ZCCHC12 MVD ZBTB22 SLC6A9 TAP2 PAQR5 EBI3 P2RY13 S100A8 CASP1 IL15RA ZCCHC2 LGALS8 TRIM21 RNF31 MOCOS GSDMD USP25 TRIM56 ZC3HAV1 SPPL2A SELL RBM43 TDRD7 PCGF5 CCRL2 MORC3 AZI2 ANKFY1 FPR1 ATP6V0D2 TFRC NFE2 INPP1 DDX60 CCDC77 NPR2 RNF19B LGALS9 TNFSF13B ORC4 MX2 TMEM140 CASP7 TOP1 COA7 DGKH SLC28A3 CSTB RHBDF2 N4BP1 NCEH1 SMCHD1 SOD2 FAS PARP3 PIK3AP1 GTPBP2 TRIM26 HMGN2 CDA MBD2 APBA1 ACTG2 ADAM8 NEU2 RNF125 PGK1 SEMA4D RIT1 UBE2B NCF2 DOK3 HLX PIAS1 CTSF F2RL2 UBAP1 PRKAB1 ACOD1 BAK1 ARPC5 WIPI1 BST1 GAB2 FFAR2 RIN2 FILIP1 ING2 G6PD PMM2 ABR AP1S3 SLC31A2 CPNE3 OTUD5 NLRC4 GDA KEAP1 PRKAA1 FIG4 DRAM2 ZFAND5 DAP NOD1 VCPIP1 RANBP10 AP3M2 CYP39A1 ABCB1B WSB1 UGCG FZR1 PFKFB4 MAX GMEB2 LPIN2 ABTB2 TTC39B MRPL3 CSGALNACT1 STOML1 MIER3 TMEM156 PHRF1 UNC5A H2BC18 C1GALT1C1 CRIPT PATL2 RUFY4 IGTP IFI47 IFI209 IQGAP2 H2-T24 SLFN1 ETNK1 SIGLECG GRHL1 PRR14 BTBD10 BMT2 CHRDL2 TTYH2 CACFD1 FAM177A1 XPO7 UROS EPB42 SLC35E1 MKLN1 FBXO30 TSSK3 KCNN3 TTC21A TMEM8B I830077J02RIK CDS1 OSBPL9 CEPT1 SLX1A MIEF1 CHST12 DCDC2B GYG SPG20 UNC119 CLEC4N FAM212A TMEM234 KIF19 TRIM58 AIRE WDR35 KCTD12B ENSMAUG00000004249 ENSMAUG00000021526 ENSMAUG00000013430 CUNH9ORF72 ENSMAUG00000008373 ENSMAUG00000016439 ENSMAUG00000020799 ENSMAUG00000021711 ENSMAUG00000002714 ENSMAUG00000019383 ENSMAUG00000004543 ENSMAUG00000021045 ENSMAUG00000016573 ENSMAUG00000008425 ENSMAUG00000009569 ENSMAUG00000015928 GBP2B MINDY2 ENSMAUG00000012640 ENSMAUG00000020551 ENSMAUG00000011822 CUNH21ORF2 CCDC162 ENSMAUG00000008633 ENSMAUG00000009298 ENSMAUG00000018272 ENSMAUG00000015164 ENSMAUG00000002024 CUNHXORF21 ENSMAUG00000008353 ENSMAUG00000004831 ENSMAUG00000014350 ENSMAUG00000021593 ENSMAUG00000010143 ENSMAUG00000001228 ENSMAUG00000008914 ENSMAUG00000001018 ENSMAUG00000012460 ENSMAUG00000009739 ENSMAUG00000010500 ENSMAUG00000015998 ENSMAUG00000004389 ENSMAUG00000001345 ENSMAUG00000004852 ENSMAUG00000005493 ENSMAUG00000000565 ENSMAUG00000018779 ENSMAUG00000015135 ENSMAUG00000000936 ENSMAUG00000014385 ENSMAUG00000018375 ENSMAUG00000017934 D16ERTD472E PGGHG ENSMAUG00000016905 ENSMAUG00000017813 ENSMAUG00000017510 8-MAR ENSMAUG00000006781 ENSMAUG00000000926 ENSMAUG00000000846 ENSMAUG00000000248 ENSMAUG00000009872 GM12248 ENSMAUG00000006930 ZP3R ENSMAUG00000016638 ENSMAUG00000020193 ENSMAUG00000016348 ENSMAUG00000017554 ENSMAUG00000009831 ENSMAUG00000009985 CUNH19ORF66 CUNH11ORF68 ENSMAUG00000017957 ENSMAUG00000007782 ENSMAUG00000017275 SIGLECE ENSMAUG00000019942 ENSMAUG00000019318 ENSMAUG00000014013 ENSMAUG00000012506 ENSMAUG00000019840 ENSMAUG00000005007 ENSMAUG00000010948 CUNH10ORF105 CUNH7ORF49 ENSMAUG00000014318 ENSMAUG00000019682 ENSMAUG00000021205 ENSMAUG00000012726 GRAMD2A ENSMAUG00000007175 ENSMAUG00000004294 4930539E08RIK ENSMAUG00000012403 ENSMAUG00000018493 ENSMAUG00000019177 CUNH15ORF48 ENSMAUG00000018991 ENSMAUG00000012224 ENSMAUG00000017395 ENSMAUG00000009900 ENSMAUG00000018309 FAM241A ENSMAUG00000008483 ENSMAUG00000014158 CUNH19ORF12 CEACAM18 ENSMAUG00000009126 ENSMAUG00000017592 CLDN13 ENSMAUG00000004308 ENSMAUG00000021919 ENSMAUG00000009998 ENSMAUG00000011807 ENSMAUG00000003507 ENSMAUG00000020114 ENSMAUG00000017689 ENSMAUG00000010003 MIR147 ENSMAUG00000015948 ENSMAUG00000017465 ENSMAUG00000005814 ENSMAUG00000018005 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 2 from GSE162208 Bulk RNA-sequencing was performed on blood of SARS-CoV-2-infected hamsters at 2 days post-infection with SARS-CoV-2. MAOA CEP250 PIK3R2 ERMP1 SARS2 NEK9 CDH17 PKP2 ASAP2 NOL10 FCER2 NF2 KCNQ1 EHBP1 MRPS27 FRMD6 PABPC4 VARS MFGE8 G3BP1 PES1 PRKAR2A ASAH2 GFER TMEM236 PLEKHA5 RPS6KA5 NAGLU EIF4B MIF4GD CGNL1 ZC3H12D LZTS3 PEAK1 CD180 PLCE1 FAM214A KRT19 RND3 FMN1 PLEKHG1 TMEM109 PYGB TMC6 TOMM40 TAOK2 RMDN3 KSR1 PDCD11 ZNF316 SH3TC1 PRKCSH EMC10 SUMF2 VKORC1L1 B3GNT7 EIF3B NDST1 TRIM65 CLUH PPP1R12C MRC1 ARHGAP31 ME1 CEBPA LPL MARVELD1 MYO1E FLT3 ALCAM CTNND1 FADS1 EIF4G1 SLCO4A1 MYO7A PTPRO SNX8 LTBP4 SIGIRR MIB2 KLRG1 SH2D2A SOX13 LLGL2 SLC2A8 PKP3 PPP1R16A RARG SLC7A1 WLS CLSTN1 PYGO2 GMPS NFIC IRF4 FCN1 WDTC1 TNK2 SLC12A7 NPEPL1 DDR1 SGSH TCF19 CTSW IL2RB CX3CR1 TBX21 EOMES CHL1 CA7 RASA4 MAMDC2 SPAG4 ID3 RAPGEF2 SPECC1L GPAM CPNE7 IMPAD1 CETN2 PRPF19 AGO1 PHLDA1 NUCKS1 FAM160B2 RFTN1 MEGF8 TMEM147 MFHAS1 KIFC3 ISM1 SYNGAP1 GPR157 GPX3 SYNCRIP PIGP KDELC1 APEX1 GEMIN5 NUDC FKBP4 POLR1C ANAPC7 MN1 MNS1 PIK3C2B CLIP2 KDSR TXNDC16 PLCB1 ADAMTS14 NCR1 EXTL3 CCR6 ALG9 SLC27A1 FAM185A IARS MAD1L1 IMPACT DNAJC3 GALNT11 ENTPD4 LPCAT1 EMP1 RCAN1 VAT1 NOSTRIN CBR3 AMPD2 KLRK1 CDON SLC6A7 MEX3B SPRYD4 ZAN HEPACAM OLFM1 CSPG4 SLC17A9 GPRC5D TNFRSF25 CD209B CD209A NUBP1 EXOSC7 MTR PRMT1 SPRY1 PPP5C FKBP14 CRLS1 DHX35 RYR3 DDX54 USP36 KIF13A OPA3 THBS3 GNL3 CEBPZ P4HA1 TBL3 GAL MAZ KCTD15 BAIAP2 ZNF219 METRN MBD3 TET3 FASTK CCDC114 PLXND1 LUZP1 SLC39A7 TIMM13 FBXO31 TSPYL2 DTX4 SUN1 PDGFRB GLT8D1 NAP1L4 FDPS RPS6KA2 COG6 PDGFA GSPT1 PTK7 YIPF2 LIG4 PLXNA1 ELAC2 SUFU TMPRSS9 ZBTB4 HIP1R MAST2 PTPRF CAMKK2 MRTFB IFT57 ABCA9 TMEM119 ABCA3 H2-OA CAMK2G IVD UGT1A1 TMPPE TNFRSF13B GSTM3 PSMG1 SLCO3A1 CYP2U1 ABCB8 IMPDH1 COL5A1 AIFM2 GPSM1 ALDH1A2 TIAM1 MET XPO5 RCC2 NUP188 SHMT2 WDR4 VPS8 HSPA9 PLOD3 EHD2 KIAA1147 NEURL4 RHOBTB1 BICD2 TMEM55B BAHCC1 GSE1 LRRN3 PGAP3 IZUMO4 AFAP1 ESPN KLHL13 ZNF608 MAN1C1 CD109 IGF2BP2 TRPC1 ZNF146 ANKRD28 FBXL19 AARS2 HGSNAT USP6NL STX2 NME3 ANKRD10 ZSCAN26 SETD1A SUGP2 POLR3D GOLIM4 AHDC1 IRGQ SMYD2 TBC1D16 PPM1L BTNL9 PYURF PLPP5 TTC28 MBTPS1 HNRNPR PRKD3 SH3BP5 VAV2 RBM12B DAG1 THAP3 RBM19 TVP23A TBRG4 FMNL3 ACACB TUSC1 SMARCC1 PDXP PDP2 CCNY ARHGEF40 SNX30 ARMC5 NSUN2 PHLPP1 PPP1R3E NAT10 RAB12 PUS1 IMMT EXT2 ZFP385A TFAP4 RTL6 POFUT2 ULK4 SLC2A13 MFSD8 BIVM LZTS2 SOGA1 POMGNT1 HCN2 WDR6 EML3 SDCCAG8 GABBR2 ENDOV AMIGO1 NKAPL DAGLA KLHL17 PNMAL2 DUSP3 ATL1 TRMT44 MTO1 RPUSD4 KLHL7 NOM1 RCL1 PLEKHG5 FUT11 SHISA8 TRIM44 MIEF2 INTS3 POMT2 SFI1 ERCC6 CALHM2 GNPTAB NOL4L FAM151B NT5M CFAP73 GRB14 ST3GAL3 RIOX2 CBFA2T3 DDX55 ZFP296 TTC7 ZFP9 C130050O18RIK ZFP512B GTF2IRD2 ZNF22 VIPR2 NSMAF KDM2B GGT5 SAMD3 DNAJB13 TRMT2A NAT8F5 ENSMAUG00000017789 ENSMAUG00000014380 ENSMAUG00000000732 ENSMAUG00000006329 ENSMAUG00000019086 ENSMAUG00000018864 VWA7 ENSMAUG00000008961 ENSMAUG00000002614 ENSMAUG00000009145 ENSMAUG00000015223 ENSMAUG00000003633 ENSMAUG00000019334 ENSMAUG00000002629 ENSMAUG00000020499 ENSMAUG00000012274 ENSMAUG00000011843 ENSMAUG00000008621 DUSP22 SNORD110 ENSMAUG00000018843 ENSMAUG00000016341 ENSMAUG00000020746 CUNH12ORF73 ENSMAUG00000011939 ENSMAUG00000001483 ENSMAUG00000005244 ENSMAUG00000012848 ENSMAUG00000019639 DELE1 ENSMAUG00000000459 ENSMAUG00000013706 ENSMAUG00000018211 CD209C ENSMAUG00000009986 ENSMAUG00000016501 CUNH3ORF70 ENSMAUG00000012655 ENSMAUG00000004849 ENSMAUG00000002685 ENSMAUG00000016231 ENSMAUG00000013338 TMEM17 CCNQ ENSMAUG00000015100 ENSMAUG00000022219 ENSMAUG00000006032 CD276 ENSMAUG00000021069 ENSMAUG00000017772 SNORD21 ENSMAUG00000019339 ENSMAUG00000009884 ENSMAUG00000003958 ENSMAUG00000009219 CUNH1ORF54 ENSMAUG00000010270 CASTOR2 ENSMAUG00000019905 ENSMAUG00000005174 KIF16B ENSMAUG00000008307 TWNK ENSMAUG00000008684 MFSD7A ENSMAUG00000016295 KCNC1 ENSMAUG00000005765 CD209E ENSMAUG00000000395 ENSMAUG00000020948 ENSMAUG00000009089 ENSMAUG00000014369 CPED1 ENSMAUG00000012535 ENSMAUG00000016958 ENSMAUG00000021089 ENSMAUG00000016575 ENSMAUG00000019923 ENSMAUG00000014007 KDF1 ENSMAUG00000008298 ENSMAUG00000004046 LIPT2 ACTR8 ENSMAUG00000001480 ENSMAUG00000021154 ENSMAUG00000005190 ENSMAUG00000008416 LRMDA CARMIL3 ENSMAUG00000001962 Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 3 from GSE162208 Bulk RNA-sequencing was performed from blood of SARS-CoV-2-infected hamsters at 3 days post-infection. UBB MISP CCL2 CCL5 MVP VDR TMPRSS3 NMI DDX58 TBK1 NPC2 CXCL10 TRIM15 TOR1AIP1 TMBIM1 TUBA8 LAP3 GGT1 RBCK1 FASLG TUBA4A STAT1 TRIM25 B2M CNDP2 EIF2AK2 RARS MOV10 FRMD4B YWHAH FERMT3 ISG15 SRC KALRN MX1 G3BP2 TMBIM4 UBE2E1 CNTD1 VLDLR PTTG1IP TMEM86A DDAH2 TBCB TNFSF10 PTGFR MAP6 CCL8 ESRP1 ISG20 AIF1 UNC93B1 LAIR1 ENPP4 PARP10 LGALS3BP TOR1B RNASEL TOR3A LEPROT CYBA CORO1B DOK2 BST2 SLAMF8 HK3 MYOF SAP30 CDKN3 RAB20 GLRX NEK2 TMEM106A POMP IFI44 KNSTRN AURKA DLGAP5 EPSTI1 SMTN LTA4H VPS25 RASGEF1B GNPDA1 TPM2 ANGPTL6 SLC2A6 ITGA2B AGRN CARD14 FAM83G CLU IBSP WNT5B CD63 PSMA3 SLC24A3 PWWP2B HELZ2 OGFR PLPPR2 KLRD1 RSAD2 GPR65 KLRC1 IDO1 IRF7 NKG7 ZBP1 AOAH NLRC5 PYCARD GBP5 CKAP2L TAP1 GZMA FAM26F ZWILCH XCL1 SLAMF9 CCR5 CLEC7A NDC80 LAG3 APOBEC1 FCER1G CD84 OAS2 SIGLEC1 PSMB8 CD274 APOL6 DHX58 FBXO39 TREX1 CMPK2 IFIT2 EVI2A CLEC4E HERC6 NPRL3 MLKL STAT2 PML ADAR NAMPT GBP2 NT5C3A PARP9 PARP12 HSH2D XDH LIPG IFI35 SOCS1 MITD1 UBE2L6 UBA7 GBP7 IRF2 PSME1 TMCC2 CLIC4 PSME2 HPCAL1 HMGCS1 DTX3L ATP6V0E1 IRF9 PSMB9 FABP5 BCAP31 VPS28 RNF114 NUPR1 TAPBP BRK1 TMEM50B FHL1 TYROBP ACTA1 COX6B1 RAB11A UBE2V1 RNASE6 THEMIS2 FPR2 NDUFA7 S100A13 SAMSN1 LST1 MYCT1 SERPINI1 AICDA TNFRSF14 MAPRE3 CSRNP1 ZNFX1 UBE2L3 PDLIM1 PDZK1IP1 MRPL27 SMIM20 PSMD10 VMP1 PAM PSMD14 CMC1 TMEM50A SNX10 AMIGO2 EMC9 TACR2 VGF LTC4S TLDC2 GP1BB TTC32 SRXN1 MSMO1 SQLE TIFAB MVD ZBTB22 TAP2 PRF1 CASP1 IL15RA ZCCHC2 SMOX TRIM21 GSDMD USP25 RBM43 TDRD7 PCGF5 MORC3 ANKFY1 SPNS3 SLC6A4 TMEM40 INPP1 TESC DDX60 RNF19B LGALS9 TNFSF13B MX2 TMEM140 CASP7 P2RY1 COA7 CSTB SMCHD1 FAS GTPBP2 TRIM26 RSU1 HMGN2 CDA GZMB MBD2 PLEK RASSF4 SEMA7A TUBB3 CALD1 ACTG2 B3GNT6 NEU2 GFI1B PRDX2 TWF1 TRAPPC1 UBE2B IDI1 HFE CTSF MFSD2B STX8 XPNPEP1 STARD3NL ACOD1 BAK1 WDSUB1 NXN CMTM3 ANXA4 NACC2 FFAR2 THOC7 PRKAR1B ITPA LSS MPC1 G6PD DAPP1 RGS18 PARVB PMM2 AP1S3 ZFYVE9 FDFT1 SNX2 CPNE3 ACTN3 LPP DCLK1 ATG7 FIG4 PRR5L DAP TRPC6 NOD1 VCPIP1 ADGRG5 CYP39A1 ABCB1B SLC27A6 ALOX12 MAPK12 PSMA5 RHOC NDUFS5 CYB5R4 HNMT CTDSPL FAM213A DYNLRB1 SLC41A3 F11R KCNMB4 MRPL3 PIF1 STOML1 NTN4 CNP PHRF1 OPHN1 UNC5A TMEM134 FRG1 CRIPT PATL2 IGTP IFI47 2310039H08RIK IFI209 H2-T24 SLFN1 MFAP3L RAB3D BDH2 MRVI1 CHRDL2 TTYH2 TSPAN9 INAFM2 TBCEL HTR7 KCNN3 KCNA3 TCTEX1D1 CDS1 GP5 CEPT1 CHST12 NMNAT3 MAN2B2 5-SEP CLEC4N HSPA12B FAM212A SYTL4 DEF8 MTG2 CCDC28B TRIM58 AIRE ICAM4 WDR35 CCDC102A SLFN14 ENSMAUG00000004249 ENSMAUG00000013430 ENSMAUG00000008373 ENSMAUG00000016439 ENSMAUG00000021711 ENSMAUG00000002714 ENSMAUG00000021045 ENSMAUG00000016573 ENSMAUG00000008425 ENSMAUG00000009569 GBP2B ENSMAUG00000020551 CCDC162 ENSMAUG00000008633 ENSMAUG00000018272 ENSMAUG00000015164 CUNHXORF21 ENSMAUG00000014350 ENSMAUG00000010143 ENSMAUG00000001228 ENSMAUG00000008914 ENSMAUG00000001018 ENSMAUG00000012460 ENSMAUG00000009739 ENSMAUG00000010500 ENSMAUG00000015998 ENSMAUG00000004389 ENSMAUG00000001345 ENSMAUG00000005493 ENSMAUG00000000936 ENSMAUG00000014385 ENSMAUG00000018375 ENSMAUG00000016905 ENSMAUG00000017510 ENSMAUG00000000846 ENSMAUG00000000248 ENSMAUG00000009872 GM12248 ENSMAUG00000006930 ZP3R ENSMAUG00000016638 ENSMAUG00000016348 ENSMAUG00000017554 ENSMAUG00000009985 CUNH19ORF66 CUNH11ORF68 ENSMAUG00000007782 ENSMAUG00000019318 ENSMAUG00000014013 ENSMAUG00000010948 CUNH7ORF49 ENSMAUG00000014318 ENSMAUG00000019682 ENSMAUG00000007175 ENSMAUG00000004294 4930539E08RIK ENSMAUG00000018493 ENSMAUG00000019177 ENSMAUG00000018991 ENSMAUG00000012224 ENSMAUG00000017395 ENSMAUG00000009900 FAM241A ENSMAUG00000008483 ENSMAUG00000014158 ENSMAUG00000009126 ENSMAUG00000017592 CLDN13 ENSMAUG00000021919 ENSMAUG00000009998 ENSMAUG00000018005 ENSMAUG00000019339 ENSMAUG00000004046 ENSMAUG00000001962 ENSMAUG00000009393 ENSMAUG00000013905 ENSMAUG00000020394 ENSMAUG00000017412 ENSMAUG00000011577 ENSMAUG00000014976 ENSMAUG00000007111 ENSMAUG00000008538 ENSMAUG00000014127 TRPT1 ENSMAUG00000007943 ENSMAUG00000020841 ENSMAUG00000001414 ENSMAUG00000006010 ENSMAUG00000016015 ENSMAUG00000006550 ENSMAUG00000018359 ENSMAUG00000010592 ENSMAUG00000013725 KLRE1 ABCA14 ENSMAUG00000008734 ENSMAUG00000015635 ENSMAUG00000014085 CUNH20ORF27 SECTM1A ENSMAUG00000001395 ENSMAUG00000015721 ENSMAUG00000019784 CUNH10ORF99 4930438A08RIK MILL2 ENSMAUG00000009345 ENSMAUG00000018978 ENSMAUG00000019262 ENSMAUG00000020752 ENSMAUG00000016894 ENSMAUG00000007454 ENSMAUG00000016004 ENSMAUG00000014351 ENSMAUG00000006511 ENSMAUG00000011951 ENSMAUG00000018352 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 3 from GSE162208 Bulk RNA-sequencing was performed from blood of SARS-CoV-2-infected hamsters at 3 days post-infection. MAOA SPTB SARS2 XPO6 ABCC1 ANPEP PFAS FCER2 ING5 PRRC2B BRAF CLCN6 UBAP2 CEP68 FRMD6 DNMT1 RSPH6A ATM MGAM WFS1 ELK4 CRTC3 TTC38 ASAH2 ERC1 VPS13B CPT1A GPR155 BCL2 DDAH1 SH3RF1 GATAD2B RALGPS2 MYRIP PEAK1 CD180 GALNT3 FNIP2 GADD45A FMN1 PLEKHG1 TTC22 ANKRD52 KSR1 MAPK8IP3 STEAP3 NUMA1 MYADM CAD KHNYN CIC CLUH MRC1 CD101 E2F2 MYO1E FLT3 ALCAM CTNND1 ADORA3 MPP6 PTGS2 RAB11FIP5 EFNA5 CDS2 ZFP36L1 SLC2A8 MMP25 BCL9L ITPR3 PYGO2 NAV2 TFCP2 IRF4 MLLT11 SOX12 RGP1 KMT2B RERE RNF44 TNK2 CSNK1D KDM4B NPEPL1 MNT ULK1 SBNO2 ATG2A SGSH PRR12 PGLYRP2 CHL1 SLC4A1 SLC25A22 GRASP RAPGEF2 SPECC1L GPAM CPNE7 KLF9 LITAF ITPRIPL2 AGO1 FNDC3B LRG1 NUCKS1 ZDHHC18 KDM6B CREB5 ISM1 PADI4 WSCD1 CCND2 KLHL11 FOXK1 SLC14A1 GPR157 SKI IRF2BPL CHAC1 SERTAD2 KANSL1 ZBTB34 PPRC1 FLOT2 SGMS1 NOC3L ABCB10 SERINC5 KLF7 PIK3C2B BLCAP KDSR CEP192 TXNDC16 DHRS13 ABL2 EXTL3 CSF3R TNFRSF13C CCR6 TSPAN33 DGAT2 SLC27A1 PELI2 PVRIG CRISPLD2 TTF2 DCPS KBTBD7 SMAD5 IMPACT PDPK1 TULP4 PAQR8 IGF1R SEMA3G GFPT1 ETS2 SLC28A3 VAT1 IL12A MS4A3 MAST3 RGS17 ITPRIPL1 GNE DENND3 LONRF1 IL1RAP XYLT1 OLFM1 SLC30A3 DCST1 CCDC184 ADAM19 GPRC5D RNF144A ETV3 SH3TC2 AMDHD1 HS3ST3B1 TNFRSF25 CD209B RUBCN CD209A THAP12 FGD3 MTR AGO2 NFATC1 TNKS MAP4K4 CDK6 WIPI2 NFATC2 CPPED1 STK10 CALCOCO1 ALDH3A2 ERCC4 GNL3 CEBPZ ARID1B MAP3K3 ATXN1 SYNE1 SLC16A13 AKAP13 MAZ COL27A1 NCOR2 METTL22 MFNG NME8 BCL6 CCDC114 PROK2 SSH2 PLXND1 PRDM2 DCAF5 VPS13D FBXO31 TSPYL2 SSH1 SUN1 NISCH RPS6KA2 DHX33 PTK7 IGF2R ADCY1 LMTK2 MAGI3 ZBTB4 DNAH8 HIP1R RALGAPA2 WNK2 CAMKK2 TXNRD1 DNMT3A TBC1D12 DYRK2 EIF2AK3 CAMK2G ULK2 ATG14 FBXO32 SLC26A11 STK11 SESN3 TMPPE TNFRSF13B IMPDH1 NCOA1 SLC23A2 UGCG RRM2B XPO5 RCC2 CDK12 AKNA SH2D3C PLOD3 SPSB1 PDHA1 AHCYL2 DENND6A KLHL18 SCAF4 RBM33 NEURL4 SIK3 RHOBTB1 ITSN2 INO80 BICD2 MED13L SKIL BAHCC1 KIF21B GSE1 SLC25A37 SFXN2 NRM GALNT10 DIP2B ESPN CPD CASD1 ZNF608 ANKRD28 PDK2 KCNK5 EFCAB12 FRS2 ATRN USP6NL PHLPP2 SVIL LRRC8B CDR2 CLIP1 ANKRD10 ZSCAN26 DNMBP DOCK5 PAOX ATL3 FBXL20 ATP11A TTC28 ANKS6 PAIP2B ACAD11 PRKCB CCDC88C SH3BP5 VAV2 SOCS4 CEP85L RBM12B OTUD3 HEATR5A FMNL3 KLHL2 SPRTN ACAP2 RSBN1 SSBP3 SMARCC1 RALGPS1 PDXP SPAG1 PDE4C BRD3 SNX30 MRM2 YPEL2 FOXN3 NAT10 RAB12 CPOX RAD50 PTDSS2 FYTTD1 1300017J02RIK EBF1 CHD7 NAT6 DDX51 RTL6 UNK REEP3 OSBPL8 ATN1 MINK1 SNAPC4 TMEM64 CPNE8 TRAF3IP1 PALM ZNF777 RAPGEF4 RCBTB1 GABBR2 TMED8 SLC22A17 ENDOV ABHD15 PNMAL2 ACTR5 AMER1 TAF4 KLHL7 MTMR10 RNF169 ARHGAP33 IQSEC1 CRACR2A SHISA8 TRIM44 MIEF2 KCNQ5 ERCC6 THADA SLC35F2 NOL4L CLASP1 ANKRD44 NT5M AJAP1 NEURL2 MAML3 IFT172 ZCCHC8 ST3GAL3 TTC7 DOC2G DOC2G ZFP592 ZFP9 KRBA1 ZFP512B MAP3K12 ZFP827 GTF2IRD2 VIPR2 LRCH3 NSMAF EVC2 NFASC RIMS2 CCSAP GGT5 HYAL3 PRR18 DNAJB13 ENSMAUG00000000732 ENSMAUG00000018864 ENSMAUG00000008961 ENSMAUG00000002614 ENSMAUG00000015223 ENSMAUG00000011843 ENSMAUG00000016341 ENSMAUG00000000459 ENSMAUG00000013706 CD209C ENSMAUG00000009986 ENSMAUG00000022219 ENSMAUG00000017772 ENSMAUG00000009884 ENSMAUG00000003958 CASTOR2 ENSMAUG00000005174 ENSMAUG00000003094 ENSMAUG00000000482 ENSMAUG00000009836 ENSMAUG00000011929 ENSMAUG00000019956 ENSMAUG00000021442 ENSMAUG00000007322 ENSMAUG00000003727 ENSMAUG00000020573 ENSMAUG00000005441 ENSMAUG00000002343 4931406P16RIK CUNH5ORF24 ENSMAUG00000001636 ENSMAUG00000018765 ENSMAUG00000012428 ENSMAUG00000007599 ENSMAUG00000014781 AFG3L1 ENSMAUG00000010385 ENSMAUG00000018348 ENSMAUG00000006044 ENSMAUG00000008880 ENSMAUG00000019742 ENSMAUG00000006659 ENSMAUG00000007022 ENSMAUG00000013625 ENSMAUG00000014548 ENSMAUG00000002812 ENSMAUG00000005295 ENSMAUG00000012054 ENSMAUG00000006120 ENSMAUG00000015247 ENSMAUG00000004373 1810055G02RIK ENSMAUG00000014090 ENSMAUG00000001026 ENSMAUG00000013003 ENSMAUG00000012134 ENSMAUG00000006590 ENSMAUG00000002581 ENSMAUG00000012350 D5ERTD579E ENSMAUG00000002757 ENSMAUG00000007378 ENSMAUG00000019138 ENSMAUG00000005712 ENSMAUG00000020379 ENSMAUG00000018705 ENSMAUG00000014080 ENSMAUG00000014169 MIR455 ENSMAUG00000011729 ENSMAUG00000008611 ZFP831 ENSMAUG00000012542 ENSMAUG00000014008 ENSMAUG00000003040 ENSMAUG00000011672 ZFP799 ENSMAUG00000010998 ENSMAUG00000009360 ENSMAUG00000021055 FAM120B Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 5 from GSE162208 Bulk RNA-sequencing was performed for blood of SARS-CoV-2-infected hamsters at 5 days post-infection. MAOA CSNK2B TBCA NUDT2 ERGIC1 PKP2 PCK2 DDX58 BCKDK UBE2D3 YIF1A UBXN1 ZCRB1 SRP54 PSMC6 ERP44 NUTF2 STAT1 IFITM2 NDUFB9 EIF2AK2 FAU RARS NEDD8 ISG15 UBE2I MX1 MTFR1 VAMP8 NDUFB6 PSMA2 BTF3 RPL9 HES1 RPL27 RPL37 SLC25A4 RPL24 CKS2 KRT19 WDR38 ESRP1 CCND1 RPS27 STMN1 CCT5 MYOF IFI44 MAPK6 MTCH2 METTL9 BUB1 PRDX1 CCT8 CLDN7 COX5A KIF23 PSMB2 MTHFD2 PSMB7 METAZOA_SRP HINT1 CKS1B AP1M2 LAMA5 GMPS TMEM88 PSMA3 HELZ2 IRF7 NLRC5 TAP1 ACSBG1 IL2RB GZMA LAG3 APOBEC1 TNNT2 SIGLEC1 PSMB8 APOL6 IFIT2 ADAR NAMPT TNFRSF12A GBP2 UBA7 GBP7 TMA7 ATP6V0C HMGN1 CLIC3 IRF9 RHEB NDUFA3 PSMB9 EIF3I MDH2 SNRPD2 PSMC2 S100A6 NUPR1 HCFC1R1 RPL35 SRP14 PSMB4 KRTCAP2 ATF4 PIM3 ROMO1 MRPL28 CFL1 COX6B1 RPL36AL EDF1 RPS27L ATP5J2 ATP5C1 NDUFA7 GPX4 TMEM147 RBM8A CAMK1 CHAC1 TMEM258 DPY30 MECR HMGB3 MRPL24 CDC123 S100A11 MIF SRM MRPS33 AIFM1 CFL2 SARNP TIPIN TFPT IMMP1L MAGOH COPS5 MRPL2 STK39 VMP1 PCNA BCAS2 NDUFA12 ATP5L RFC4 PSMA1 PSMA7 CMC1 CCT7 RUVBL1 UXT SNRPA NAA10 ERH NAA20 TMSB10 RPL32 TMEM55A RUVBL2 FKBP4 ANKRD1 NOP14 DOK4 YTHDF2 MED10 CDCA7 MRPL47 NCR1 PRF1 ASNS SSNA1 GCAT ACP6 SNRPA1 PPIL1 MX2 GARS PMM1 NDUFB4 GZMB KLRK1 GLRX3 PSMD7 RER1 SEC13 OLA1 COPS3 UBE2V2 PFDN4 SEM1 TSG101 ESD TMEM11 SF3B6 STARD3NL PPID PHGDH HM13 SNRNP27 SCNM1 DTNB CCT6A NIP7 BTG3 BRIX1 CWC15 PMF1 BAIAP2 MCTS1 CYSTM1 ITGA3 EMC7 CCN2 EIF4EBP1 MRPS22 NOD1 RANBP1 HAX1 POLB PSMA5 BABAM2 TIMM50 MRTO4 H3F3B TXN1 ENO3 NSFL1C TIMM17A FAM96B BRCC3 DYNLRB1 SSBP1 CHCHD3 TOMM7 MRPS21 NAA38 MRPL21 NMD3 BEX3 EIF6 IFI47 PSMD12 DNAJA2 H2-T24 SLFN1 ATP5F1 RLIM SERBP1 NAXE CNIH1 DENR CXADR GTF2A2 MINOS1 CFAP36 MRPS24 IMMT MRPL45 PSPH COPS2 DTD1 EIF2S2 SBDS MRPL38 PRMT7 CEPT1 EIF2B3 MRPS18B MALSU1 E2F5 PRICKLE4 SNU13 KLRB1F RAB28 POLR1D ENSMAUG00000016439 ENSMAUG00000008425 ENSMAUG00000020551 ENSMAUG00000018272 ENSMAUG00000010143 ENSMAUG00000005493 ENSMAUG00000018779 ENSMAUG00000000936 ENSMAUG00000014385 ENSMAUG00000009985 ENSMAUG00000010948 ENSMAUG00000004294 ENSMAUG00000018493 ENSMAUG00000019177 ENSMAUG00000009998 ENSMAUG00000006329 ENSMAUG00000019334 SNORD110 CCNQ ENSMAUG00000001480 ENSMAUG00000011577 ENSMAUG00000007111 ENSMAUG00000007943 ENSMAUG00000016015 ENSMAUG00000008734 ENSMAUG00000001395 ENSMAUG00000015721 ENSMAUG00000020752 ENSMAUG00000013742 ENSMAUG00000008420 ENSMAUG00000013383 ENSMAUG00000011765 ENSMAUG00000001647 ENSMAUG00000001796 ENSMAUG00000018350 U2 ENSMAUG00000017822 ENSMAUG00000014400 ENSMAUG00000009168 ENSMAUG00000011772 ENSMAUG00000006910 ENSMAUG00000006005 ENSMAUG00000002128 ENSMAUG00000010388 ENSMAUG00000006430 ENSMAUG00000009701 ENSMAUG00000012078 ENSMAUG00000015974 ENSMAUG00000013985 ENSMAUG00000002746 ENSMAUG00000008646 ENSMAUG00000010877 ENSMAUG00000002061 ENSMAUG00000015302 ENSMAUG00000014402 ENSMAUG00000016592 ENSMAUG00000008105 ENSMAUG00000015943 ENSMAUG00000009054 ENSMAUG00000017899 PDCD6 ENSMAUG00000015060 ENSMAUG00000010617 ENSMAUG00000017282 ENSMAUG00000013340 ENSMAUG00000004630 ENSMAUG00000018123 ENSMAUG00000008768 ENSMAUG00000003832 ENSMAUG00000003536 ENSMAUG00000014028 ENSMAUG00000014537 SNORD39 ENSMAUG00000009250 ENSMAUG00000018723 ENSMAUG00000010487 ENSMAUG00000018500 ENSMAUG00000020100 ENSMAUG00000012558 ENSMAUG00000010884 ENSMAUG00000010674 ENSMAUG00000002244 ENSMAUG00000015429 ENSMAUG00000014867 ENSMAUG00000004168 ENSMAUG00000018246 ENSMAUG00000000693 ENSMAUG00000001440 ENSMAUG00000012949 ENSMAUG00000010991 ENSMAUG00000011886 ENSMAUG00000021740 ENSMAUG00000016085 ENSMAUG00000007163 ENSMAUG00000004000 ENSMAUG00000019155 ENSMAUG00000009893 ENSMAUG00000018874 ENSMAUG00000002325 ENSMAUG00000005036 ENSMAUG00000007102 GM20390 ENSMAUG00000012830 ENSMAUG00000018374 ENSMAUG00000013568 ENSMAUG00000009883 ENSMAUG00000013225 ENSMAUG00000008077 ENSMAUG00000001485 ENSMAUG00000001457 ENSMAUG00000005143 H2AJ ENSMAUG00000021775 ENSMAUG00000017818 ENSMAUG00000010470 ENSMAUG00000008637 ENSMAUG00000012324 ENSMAUG00000017204 ENSMAUG00000008911 ENSMAUG00000007515 ENSMAUG00000008132 ENSMAUG00000017650 ENSMAUG00000001312 ENSMAUG00000017035 ENSMAUG00000001091 ENSMAUG00000009590 ENSMAUG00000019525 ENSMAUG00000003166 ENSMAUG00000007368 U6 ENSMAUG00000005696 ENSMAUG00000016933 CUNH14ORF1 ENSMAUG00000009344 ENSMAUG00000010614 ENSMAUG00000014784 ENSMAUG00000013200 ENSMAUG00000017070 ENSMAUG00000008123 ENSMAUG00000018223 ENSMAUG00000009635 ENSMAUG00000007867 GM4356 ENSMAUG00000001413 ENSMAUG00000015885 ENSMAUG00000016675 ENSMAUG00000000086 ENSMAUG00000015824 ENSMAUG00000020260 ENSMAUG00000017798 ENSMAUG00000003838 ENSMAUG00000018199 ENSMAUG00000018967 ENSMAUG00000006972 ENSMAUG00000010445 CUNH19ORF33 ENSMAUG00000020351 ENSMAUG00000007042 ENSMAUG00000018263 ENSMAUG00000016733 ENSMAUG00000021746 ENSMAUG00000018281 ENSMAUG00000008765 ENSMAUG00000010401 ENSMAUG00000006829 ENSMAUG00000017662 ENSMAUG00000006601 ENSMAUG00000009240 ENSMAUG00000017267 ENSMAUG00000021727 ENSMAUG00000012459 ENSMAUG00000008169 ENSMAUG00000015912 ENSMAUG00000000797 ENSMAUG00000011696 ENSMAUG00000006717 ENSMAUG00000008421 ENSMAUG00000019493 ENSMAUG00000009151 ENSMAUG00000002274 ENSMAUG00000001063 ENSMAUG00000015986 ENSMAUG00000020230 ENSMAUG00000001590 ENSMAUG00000008917 ENSMAUG00000019982 ENSMAUG00000002793 ENSMAUG00000017587 ENSMAUG00000015658 ENSMAUG00000008969 ENSMAUG00000017646 ENSMAUG00000011625 ENSMAUG00000017719 ENSMAUG00000000208 ENSMAUG00000022188 ENSMAUG00000018744 SNORD42 ENSMAUG00000021330 ENSMAUG00000021441 ENSMAUG00000015523 ENSMAUG00000006397 ENSMAUG00000020495 CUNH8ORF59 ENSMAUG00000021474 ENSMAUG00000015589 ENSMAUG00000010124 ENSMAUG00000016326 ENSMAUG00000016659 ENSMAUG00000002387 ENSMAUG00000010882 ENSMAUG00000021779 ENSMAUG00000017696 ENSMAUG00000014509 ENSMAUG00000002028 ENSMAUG00000003833 ENSMAUG00000000779 ENSMAUG00000017536 ENSMAUG00000016909 ENSMAUG00000001924 ENSMAUG00000011604 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 5 from GSE162208 Bulk RNA-sequencing was performed for blood of SARS-CoV-2-infected hamsters at 5 days post-infection. CD79B CYP4F14 RB1 NEK9 DAAM1 DPY19L1 CRYL1 ZBTB7B VIPR1 SPTA1 RNF41 FAM109A NGLY1 SLC27A4 QSOX2 PCNT DHRS11 CRTC3 STOM TTC38 CAT GORASP1 ASAH2 GOLGB1 PLEC TMEM236 CDAN1 COX15 TGDS LRRC61 GPR155 FECH RPS6KA5 ELL3 ND4L ZEB2 RALGPS2 TCP11L2 TET2 C2CD2L INPPL1 STEAP3 EMC10 CD37 EMILIN2 MYADM RETREG2 CIC NCLN MRC1 CD101 CEBPA LPL E2F2 ADAM15 LHFPL2 ADORA3 CALCRL DUSP7 PADI2 PTPRO CENPU PRDX3 LIPA NRIP1 ZNF365 CCR3 B4GALNT3 IKZF2 KLF2 TFDP2 TRAK2 ABCC6 APLP2 MPEG1 SERPINF1 MAPT HNF1A MITF MTOR PROSER2 SEMA4B RARG PYGO2 FRZB WNT5B ELP3 SOX6 CTR9 KIF13B EPN1 LCP2 TLR1 PLD4 CX3CR1 CD72 HSF2BP CCR1 ALAS2 SLC4A1 OSCAR SNCA PLEKHA4 RASA4 IL4I1 ACKR4 EHD4 FAM129B TPPP3 KLHL5 RAPGEF2 CA2 IMPAD1 AQP1 MYLIP TCF4 GNS SLC38A2 BNIP3L SLC6A12 POU2F2 PIK3R6 RAB30 TAGAP WSCD1 ERMAP TCERG1 LIMD1 ZFP14 SLC14A1 SKI SLC25A27 GRK1 ZSWIM6 SH2B3 MSRB2 ARFIP1 FLOT2 PAN3 COMMD8 DONSON GEMIN5 FAM117A MALT1 SERINC5 NCOA4 RSRP1 MKRN1 LENG8 GOLT1A RIPK3 KLF3 CLIP2 NR1I3 CD40 ZUFSP RASD1 TNFRSF13C CXCR5 NCKAP1L SLAMF6 ND6 PET117 EFHC1 ADRB2 KCTD12 TM6SF1 NT5DC1 NOSTRIN RHBDF2 BPGM IL12A BLNK S1PR1 MS4A1 RAB29 ADD3 MAST3 XKRX NAPEPLD PPFIA4 SERPINB8 MBLAC2 ZAN SLC30A3 DCST1 IGHM SLC16A10 NCOA7 SH3TC2 AMDHD1 KLHL14 ACP5 CA1 IRAK1 RUBCN CD209A TBCE GK PIK3CD HHEX EIF2AK4 DOT1L SOX5 SPEN UGP2 COPG2 ATG9A TM9SF1 CALCOCO1 ARL5A RAB3IL1 RCBTB2 OPA3 EIF2AK1 PINK1 FIZ1 PGPEP1 SYNE1 PTCH2 VPS18 HDAC5 MAZ ZNF219 ATP13A1 RHOBTB2 MFNG TFEC RGS18 MADD PLXND1 KCTD10 NISCH LRRC47 FAM214B PEX5 RPS6KA4 DEAF1 GAS7 CLCN2 KDM3A NCOR1 KMT2A TRPM4 HIP1R WNK2 PDGFB MYO1C RAB32 EIF2AK3 FIG4 ATG4C RPTOR SLC8B1 RORC UBR5 UBR1 GOLGA1 TNFRSF13B HACD4 EXOC4 SUCO POGLUT1 SLCO3A1 SLC15A4 LIMK1 IRS3 CCDC88A RANBP6 ALDH1A2 WDR3 UTP15 UBP1 AKNA NRROS TMOD1 PLCG2 HNMT KIAA1161 DENND6A MTMR9 SPATA2 ARID2 GAPVD1 SPIRE1 TUBE1 SLC25A37 GNA15 PRELID2 DIP2B LRMP KLHL13 FRMD5 EIF4EBP2 NHLRC3 TMEM67 TRIM36 CAPRIN2 USP6NL DIDO1 SZT2 CDR2 STX2 MTMR12 UBE2O EVI5 FAM104B SIPA1L2 SVIP PLPP5 TCTN1 PRKD3 PRKCB SBF1 VAV2 RNF10 LUC7L2 SOCS4 LYSMD3 HIC2 UBXN2B SPRTN RSBN1 RALGPS1 TRUB1 RFX2 SAV1 FAM213B NIFK GPR146 XPO7 TBCEL STK11IP RILPL1 RIN1 SLC36A4 IPMK FCHO2 CROCC FAT3 NPAT TESK1 C1QL3 ENDOV GNAO1 KDM8 SAP25 MTO1 NRDE2 DDX46 KLHL7 KLHL12 FAM131A INPP5F NPHP4 INTS6L CTU1 RUNDC3A MEF2B IFT52 KIF27 TMEM42 FAAP100 SNAP91 CDKL1 CCDC136 GPATCH2 2-MAR ISOC2A MARF1 ANKS3 PRRG1 ENOX2 IGSF10 ZNF22 VIPR2 WDR55 TBC1D14 CCSAP NOP9 PEX11B PPT2 OSGEP TFB2M TEAD2 OLIG2 KEL CDYL2 ACSM4 CNRIP1 B3GLCT ENSMAUG00000012640 ENSMAUG00000014013 ENSMAUG00000016341 CD209C ENSMAUG00000009219 ENSMAUG00000007322 ENSMAUG00000002343 ENSMAUG00000002812 ENSMAUG00000001026 ENSMAUG00000011672 ENSMAUG00000008735 ENSMAUG00000005720 ENSMAUG00000000364 ENSMAUG00000012320 UBE2D2B ENSMAUG00000000670 ENSMAUG00000020482 ENSMAUG00000001247 DGAT2L6 ENSMAUG00000008028 RNF227 ENSMAUG00000013820 ZFP382 ENSMAUG00000021341 ENSMAUG00000016443 ENSMAUG00000005659 GM4881 ENSMAUG00000006593 ENSMAUG00000001124 ENSMAUG00000012310 ENSMAUG00000019940 ENSMAUG00000009934 ENSMAUG00000021296 ENSMAUG00000019314 ENSMAUG00000017162 ENSMAUG00000011644 ENSMAUG00000019278 ENSMAUG00000016966 ENSMAUG00000005669 ENSMAUG00000015267 CUNH15ORF39 ENSMAUG00000017089 WASHC1 ENSMAUG00000013061 ENSMAUG00000007659 SNORD27 ENSMAUG00000014706 CUNH2ORF49 ENSMAUG00000008703 ENSMAUG00000005690 ENSMAUG00000008801 ENSMAUG00000015736 ENSMAUG00000007689 ENSMAUG00000021898 ND5 ENSMAUG00000017736 ENSMAUG00000021871 MIR29B-2 PFPL ENSMAUG00000017806 ENSMAUG00000000030 ENSMAUG00000000031 PHYHIP ENSMAUG00000007215 ENSMAUG00000000026 ENSMAUG00000020614 ENSMAUG00000014083 ENSMAUG00000003819 CALR3 USP50 ENSMAUG00000005702 ENSMAUG00000004576 ENSMAUG00000000029 D10WSU102E ENSMAUG00000011648 ENSMAUG00000021492 ENSMAUG00000000034 HBB-BH1 ENSMAUG00000010861 ENSMAUG00000015656 ENSMAUG00000020091 ENSMAUG00000000037 ENSMAUG00000017174 ENSMAUG00000020000 ENSMAUG00000008083 ZFP280D ENSMAUG00000003369 HBA-X ENSMAUG00000017003 ENSMAUG00000000508 ENSMAUG00000015305 ENSMAUG00000003891 ENSMAUG00000002023 ENSMAUG00000020620 OLFR646 ENSMAUG00000021786 ENSMAUG00000007251 HDGFL3 ND4 ENSMAUG00000002788 APOL8 ENSMAUG00000019331 ENSMAUG00000002219 ENSMAUG00000006536 ENSMAUG00000005916 ENSMAUG00000013210 ENSMAUG00000007535 ENSMAUG00000010437 ENSMAUG00000016980 Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 14 from GSE162208 Bulk RNA-sequencing was performed for blood of SARS-CoV-2-infected hamsters at 14 days post-infection. RPS27A TBCA MPHOSPH10 RPL12 RPL36 NMI RRP9 ESRRA UBXN1 TMEM97 FBL EIF4E2 NT5C FAU GLOD5 NEDD8 NPM1 PPIH TSR2 RBKS TIMM44 NSMCE4A VAMP8 UFC1 NDUFB6 TLCD1 BTF3 PFDN5 RPL37A RPS26 RPS16 RPL21 RPL9 RPLP2 RPS12 RPS11 RPL14 RPL27 CCDC84 RPS15A TPT1 RPL37 RPS8 NDUFB2 RPL30 SLC25A4 RPL23 RPL13A RPL24 RPS25 RPS15 WDR38 RPS13 RPS18 COX7C RPL7A AIF1 COPS9 RPS27 RPL27A BANF1 STMN1 DDRGK1 DOK2 POMP SEC11A MRPL15 PRELID1 MRPL51 METAZOA_SRP U1 KANK3 HINT1 HINT2 DNAJA3 GZMA TNNT2 PSMB8 RAMP1 PLEKHA4 TNNC2 PSME1 PSENEN RPS28 TMA7 SMDT1 EIF3G PSMB9 RPS23 RPL5 RPS19 COX7A2 EIF3I EEF1B2 RPL10A SNRPD2 RPL26 RPL22 RPS10 NDUFA13 COX8A ATP5D NDUFS6 ABRACL COX4I1 ATP5H NDUFB3 NDUFB11 RPL18 RPL35 SRP14 RPS9 RGCC PSMB4 JTB RP9 ROMO1 TRMT112 COX6B1 DNAJA1 RPL36AL EDF1 RNASE6 RPS3 NDUFA4 POLR2K CETN3 SUB1 USMG5 NDUFC2 PIN4 ATP5J2 NDUFB10 NDUFA7 SCAND1 HIGD2A MIEN1 TMEM258 DPY30 SNRPG CDC123 LAMTOR2 MRPL27 SARNP MRPS9 LSM2 SSSCA1 SRP9 VPS72 LSM7 PIH1D1 PCNA BCAS2 POLR2J ATP5L SPCS1 MRPL32 GLRX2 TMSB10 RPL32 EMC9 RPL34 NUDC SCARNA2 RPA3 SSNA1 FBLN2 CCDC38 MTIF2 MED22 CCDC91 TWISTNB ANP32B RPL23A UQCR11 SNRPB2 SNRPD3 SUGT1 SEM1 PET100 TEN1 PRMT1 TMEM11 STX8 IFT20 TOMM22 NXN BOLA2B AURKAIP1 MRPL52 NIP7 LTV1 ZC3H15 DNAJC2 CWC15 LLPH TRAPPC6A NUDT14 METRN MBD3 EIF1B RRP1 TIMM13 SIVA1 SELENOK TMPRSS9 PDE9A PTP4A3 POLR2F HYPK GSTM3 RANBP1 PDAP1 PIN1 RWDD1 RRS1 USE1 NOP53 CEBPZOS DYNLRB1 TIMMDC1 SSBP1 CHCHD3 EIF3H CTXN1 ANAPC15 MRPS21 NDUFB8 POP7 SPAG7 LONP1 PRKRIP1 LSM5 EEF1E1 ZCCHC17 MRPL43 HIGD1A D8ERTD738E EIF3M PHPT1 FBXL15 U3 SNORD15 RNASEP_NUC 5S_RRNA 7SK RNASE_MRP SNORA73 DENR LSM6 DPH3 MRM2 MZT2 SNORA62 PLAAT3 MED11 HCN2 CCDC12 TMEM242 PTRH2 EIF2S2 ZNF706 GM22009 RPRML YBEY PPP1R35 ISY1 MED30 FBXO22 INO80B OSGEP SNORA66 ENSMAUG00000010143 FAM241A ENSMAUG00000009998 ENSMAUG00000006329 ENSMAUG00000019334 ENSMAUG00000002629 ENSMAUG00000020499 ENSMAUG00000001483 ENSMAUG00000016231 SNORD21 CUNH1ORF54 ENSMAUG00000008307 ENSMAUG00000009393 ENSMAUG00000020394 ENSMAUG00000020841 ENSMAUG00000016015 ENSMAUG00000015721 ENSMAUG00000019784 ENSMAUG00000001647 U2 ENSMAUG00000017822 ENSMAUG00000006910 ENSMAUG00000006005 ENSMAUG00000002128 ENSMAUG00000010388 ENSMAUG00000009701 ENSMAUG00000010877 ENSMAUG00000017899 ENSMAUG00000015060 ENSMAUG00000018123 ENSMAUG00000003536 SNORD39 ENSMAUG00000018723 ENSMAUG00000010487 ENSMAUG00000012558 ENSMAUG00000012949 ENSMAUG00000010991 ENSMAUG00000011886 ENSMAUG00000019155 ENSMAUG00000018874 ENSMAUG00000005036 GM20390 ENSMAUG00000013225 ENSMAUG00000008077 ENSMAUG00000001485 ENSMAUG00000005143 ENSMAUG00000010470 ENSMAUG00000008637 ENSMAUG00000007515 ENSMAUG00000001091 ENSMAUG00000009590 ENSMAUG00000007368 ENSMAUG00000016933 ENSMAUG00000009635 ENSMAUG00000016675 ENSMAUG00000015824 ENSMAUG00000020260 ENSMAUG00000018199 ENSMAUG00000018967 ENSMAUG00000020351 ENSMAUG00000008765 ENSMAUG00000006829 ENSMAUG00000017662 ENSMAUG00000012459 ENSMAUG00000008421 ENSMAUG00000019982 ENSMAUG00000002793 ENSMAUG00000000208 ENSMAUG00000022188 SNORD42 ENSMAUG00000006397 ENSMAUG00000020495 ENSMAUG00000021474 ENSMAUG00000015589 ENSMAUG00000016326 ENSMAUG00000016659 ENSMAUG00000003833 ENSMAUG00000016909 ENSMAUG00000011604 HBB-BH1 ENSMAUG00000007527 ENSMAUG00000006096 ENSMAUG00000006349 ENSMAUG00000008674 ENSMAUG00000015494 ENSMAUG00000016802 SNORD73 ENSMAUG00000006758 ENSMAUG00000010575 ENSMAUG00000007459 ENSMAUG00000008499 ENSMAUG00000001910 ENSMAUG00000020552 ENSMAUG00000016494 ENSMAUG00000013093 ENSMAUG00000016545 ENSMAUG00000019451 ENSMAUG00000000899 CUNH1ORF52 ENSMAUG00000016918 ENSMAUG00000009068 ENSMAUG00000015225 ENSMAUG00000011147 CUNH19ORF43 ENSMAUG00000015675 ENSMAUG00000005639 ENSMAUG00000005911 ENSMAUG00000019145 ENSMAUG00000006390 ENSMAUG00000020656 ENSMAUG00000009679 ENSMAUG00000020543 ENSMAUG00000002516 ENSMAUG00000002388 ENSMAUG00000003793 VAULT ENSMAUG00000001917 ENSMAUG00000005216 ENSMAUG00000009392 ENSMAUG00000012178 SNORD58 ENSMAUG00000010107 ENSMAUG00000016082 U4 ENSMAUG00000017234 ENSMAUG00000010952 ENSMAUG00000009852 ENSMAUG00000017722 ENSMAUG00000013818 ENSMAUG00000005419 ENSMAUG00000013138 ENSMAUG00000008831 ENSMAUG00000006198 ENSMAUG00000017530 PCP2 ENSMAUG00000002402 ENSMAUG00000016559 SNORD34 ENSMAUG00000021183 ENSMAUG00000009790 ENSMAUG00000009545 ENSMAUG00000005900 ENSMAUG00000007708 ENSMAUG00000017341 CUNH19ORF70 ENSMAUG00000013070 ENSMAUG00000013287 ENSMAUG00000000783 ENSMAUG00000004371 ENSMAUG00000000966 ENSMAUG00000003371 ENSMAUG00000014284 ENSMAUG00000018531 ENSMAUG00000006935 GM26457 ENSMAUG00000006839 ENSMAUG00000015670 ENSMAUG00000015008 ENSMAUG00000008100 ENSMAUG00000018492 ENSMAUG00000002305 ENSMAUG00000015543 ENSMAUG00000021147 ENSMAUG00000009463 ENSMAUG00000007504 ENSMAUG00000015634 ENSMAUG00000007960 ENSMAUG00000014352 ENSMAUG00000019737 ENSMAUG00000000601 ENSMAUG00000004004 ENSMAUG00000002112 ENSMAUG00000009633 SNORD72 ENSMAUG00000015927 ENSMAUG00000018151 ENSMAUG00000006403 ENSMAUG00000009518 ENSMAUG00000007063 ENSMAUG00000001167 ENSMAUG00000000730 ENSMAUG00000020466 ENSMAUG00000022129 ENSMAUG00000018753 SNOZ196 ENSMAUG00000004883 ENSMAUG00000017959 ENSMAUG00000017838 ENSMAUG00000005925 SNORD36 ENSMAUG00000008751 ENSMAUG00000005209 ENSMAUG00000008827 ENSMAUG00000008889 ENSMAUG00000006804 ENSMAUG00000004707 ENSMAUG00000003723 ENSMAUG00000001826 ENSMAUG00000004854 ENSMAUG00000004961 ENSMAUG00000006315 ENSMAUG00000018936 SNORA72 ENSMAUG00000007359 ENSMAUG00000008205 ENSMAUG00000007497 ENSMAUG00000007482 ENSMAUG00000004880 ENSMAUG00000020049 ENSMAUG00000008811 ENSMAUG00000010065 ENSMAUG00000009750 ENSMAUG00000010957 ENSMAUG00000010373 SNORD33 ENSMAUG00000002815 ENSMAUG00000004738 ENSMAUG00000015528 ENSMAUG00000015524 ENSMAUG00000010907 CUNH9ORF172 ENSMAUG00000008799 ENSMAUG00000005110 ENSMAUG00000011402 1600002K03RIK CUNH12ORF10 ENSMAUG00000004156 ENSMAUG00000010933 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster blood Day 14 from GSE162208 Bulk RNA-sequencing was performed for blood of SARS-CoV-2-infected hamsters at 14 days post-infection. MYH9 XPO6 ABCC1 ANPEP SEC14L1 STAT3 GMIP SPTAN1 WASHC4 TNF LARP4B DAAM1 MIB1 SLC26A6 EP300 FURIN XIAP WRN CIT FYCO1 RAB14 HNF4A GPR142 ZDHHC5 RETSAT NUP214 MGAM PXN PGLYRP3 LNPEP PLEC SPTBN1 ERC1 ZC3H12C KLF12 TLN1 4932438A13RIK CPT1A MED14 ZEB2 GATAD2B STEAP4 TET2 FMN1 ABCA1 DHRS9 ARID5B SEL1L ACER3 SIK2 MBD6 DENND4B ARHGEF10L PLCB2 LRRC25 GAA USP19 MYADM PIP5K1C GGA1 CIC ZSWIM8 RARA ITGA5 LTBR ABHD2 NCSTN CD101 MYOF ARHGAP31 CYFIP1 CTNND1 KIAA0895L KIF23 PTGS2 SLC2A6 NOTCH1 ZFP36L1 RUNX2 TRAK1 ASB7 MMP25 CSNK1G1 USP32 NCOA3 BMP2K NAV2 INPP5D F2R CCDC170 SORL1 NOTCH2 SLC45A4 MED25 NBEAL2 KIF13B RNF44 CREBBP TMEM63B TBL1X FBRS MNT ULK1 MIDN TNRC18 KNTC1 PIK3R5 CHL1 NOD2 BMPR2 ZFP36 FOS SGK1 RAPGEF2 RBMS1 AMMECR1L SERPINE2 HIPK3 ARRDC3 TP53INP1 ITPRIPL2 FNDC3B WASF2 VCL KDM6B CREB5 VAMP1 SYNGAP1 TLR6 LRRK2 TLR9 FOXK1 TP53INP2 DUSP6 PPP1R15B IRS2 ZSWIM6 CHAC1 NFKBIZ ZNFX1 SH2B3 GYS1 SPRED3 PAN3 PRIMPOL RPS6KA3 SEC24B SOAT1 PTBP3 SERINC5 KLF7 NUFIP2 MGEA5 TMEM170B KDM3B KLHL24 DENND5A GLCE CD46 UHMK1 CSF3R TRIM56 ASCC3 IKZF3 WDFY4 NEB PDPK1 SECISBP2L PPP1R3D BBX CORO2A FNIP1 HERC1 DGKH SRRM2 ETS2 CPEB2 CHST15 PMAIP1 SLC28A3 PMM1 RHBDF2 N4BP1 ATP10D CDA NAV1 ATF7IP GRAMD1B LONRF1 XYLT1 PAG1 BACH1 ZAN MCAM APBB1IP LRRC63 ASPG PLAGL2 RUBCN CD93 GK MTR ITCH RET NFATC1 TNKS EEA1 GNAQ SPEN PIAS1 F2RL2 SEC16A CLTC GAB2 ASAP1 RIN2 HELZ AHCTF1 KCNJ2 ARID1B ACAP3 PLEKHM1 NLGN3 COL27A1 MLXIP TET3 IQGAP1 BCL6 ALPK1 SSH2 PLXND1 PRDM2 ATP6V0A1 DCAF5 ACP2 NISCH ARAP3 ANKRD17 ZFHX3 RNF216 PTPRJ NLRC4 IGF2R SP1 COL4A3BP LMTK2 USP9X SETD7 NCOR1 PIK3C2A MAPK7 DAPK1 WDFY3 SPG11 EPG5 ADAMTSL4 MAP1A PDCD6IP SMCR8 RC3H1 HPS3 USP45 SNX13 NUMB UGGT1 STAM2 AP1G1 SUCO TTBK2 RALGAPB NR1H3 NCOA1 MAP3K2 WSB1 UGCG BIRC6 TIAM1 ST8SIA4 CDK12 AKNA NRROS SYNJ1 KLHL18 FOXJ2 LYST SIK3 ARID2 MGA ZNF407 RNF111 ZBTB39 ZNF319 MED13L ZFX ELMSAN1 ZSWIM4 GSE1 TTC39B HIVEP1 CSNK1E DIP2B CPD MFAP3 YTHDC2 LMBRD2 GALC HSPA13 JMY HCFC1 ATRN ADNP2 DSTYK USP6NL PDE10A MED13 ALS2 RASA2 MYO5A RC3H2 SVIL HIPK1 CLIP1 LNX2 BTBD7 KMT5B 7-MAR GPATCH8 RPRD2 ZNF609 KMT2E AP3D1 PADI1 DOCK5 BICRA SOS2 ZNF516 CDK14 CPEB4 DENND4A SIPA1L2 FBXL20 TTLL4 ATP11A CELF1 PRKD3 6-MAR SIDT2 BAZ2A TMEM131L ZNF281 CEP85L AP2B1 TNPO1 HEATR5A DOCK4 VPS13C OSBPL11 ACAP2 KIF1B ANKS1A ZC3H3 CACFD1 SESTD1 ZMYND8 RFX2 HIVEP3 KDM7A EXOC6B TPCN2 PSME4 RNF38 NAT6 UBE4B AFF1 ARID3A SLC36A4 CSPP1 MAP9 FCHO2 REEP3 FAM160B1 DNAJC13 CLASP2 PLXNC1 TMED8 PCNX ABHD15 DAGLA SNX27 GP5 TRRAP PPP6R3 SYNRG PLEKHM3 FAM160A2 ARHGAP33 IQSEC1 INTS3 NNAT INPP4A NOL4L MAN2B2 BAHD1 HIP1 ZFYVE16 CBFA2T3 ZFP280C MIR5125 MORN3 TBC1D14 GGT5 NHSL2 STARD8 ENSMAUG00000021593 ENSMAUG00000015998 ENSMAUG00000017934 ENSMAUG00000006781 CUNH10ORF105 CEACAM18 ENSMAUG00000003633 ENSMAUG00000010270 ENSMAUG00000005765 ENSMAUG00000000395 ENSMAUG00000019956 ENSMAUG00000007322 ENSMAUG00000003727 ENSMAUG00000020573 ENSMAUG00000018348 ENSMAUG00000006044 ENSMAUG00000005295 ENSMAUG00000004373 ENSMAUG00000014090 ENSMAUG00000001026 ENSMAUG00000006590 D5ERTD579E ENSMAUG00000014169 ENSMAUG00000011729 ENSMAUG00000008611 ENSMAUG00000014008 ENSMAUG00000011672 ENSMAUG00000021055 ENSMAUG00000012310 ENSMAUG00000019278 ENSMAUG00000021898 ENSMAUG00000004576 ENSMAUG00000017174 ENSMAUG00000013210 ENSMAUG00000004402 ENSMAUG00000008963 ENSMAUG00000020343 ENSMAUG00000020956 ENSMAUG00000019359 ENSMAUG00000015217 ENSMAUG00000017088 ENSMAUG00000012867 ENSMAUG00000002202 ENSMAUG00000000214 ENSMAUG00000014837 ENSMAUG00000001956 ENSMAUG00000007208 ENSMAUG00000012286 ENSMAUG00000001805 SLC49A4 ENSMAUG00000000321 ENSMAUG00000015835 ENSMAUG00000001449 ENSMAUG00000013778 ENSMAUG00000013826 ENSMAUG00000012339 ENSMAUG00000000377 ENSMAUG00000013628 QK ENSMAUG00000011046 ENSMAUG00000014663 ENSMAUG00000002201 ENSMAUG00000006974 ENSMAUG00000014000 ENSMAUG00000019796 ENSMAUG00000018134 ENSMAUG00000000256 ENSMAUG00000009538 CUNH5ORF51 ENSMAUG00000020422 ZFP300 BICRAL ENSMAUG00000018328 ENSMAUG00000004758 ENSMAUG00000009384 ENSMAUG00000014493 ENSMAUG00000000688 ENSMAUG00000014930 ENSMAUG00000002454 ENSMAUG00000009856 ENSMAUG00000020019 ENSMAUG00000014365 ENSMAUG00000022099 ENSMAUG00000013774 GM24608 ENSMAUG00000002626 ENSMAUG00000016542 Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 2 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 2 days post-infection. UHRF1 RB1 CCL5 EGR1 NMI DDX58 TBK1 CXCL10 RIPK1 TOR1AIP1 LAP3 COL4A3 KLF6 XIAP F5 POLA1 GNGT2 STAT1 TRIM25 IFITM2 B2M EIF2AK2 TDP2 ITGA4 ALG11 EDEM3 ISG15 MX1 MYD88 PLEKHA7 NUDT12 MPP7 MED14 MCL1 SERPING1 CERKL TNFSF10 ZEB2 HLF FMO3 COBLL1 RICTOR SCEL OTUD7B PRSS23 ABCA1 PLEKHG1 ARID5B UNC93B1 PARP10 LGALS3BP RNASEL BST2 SLAMF8 NRP2 PLEKHN1 CLSPN SCARB2 LPL NEK2 TMEM106A IFI44 DDIT4 MSR1 FKBP5 BUB1B FGD2 MS4A4A MAFB C1QB EPSTI1 TRPM2 CCR2 MERTK SPATS2L CLEC12A ANGPTL6 MYBL1 ABCC9 SLC2A6 SLC2A3 ITGA2B AGRN USP32 ATF3 FZD4 CBFB FOSL2 HELZ2 RSAD2 IDO1 IL10RA IRF7 ZBP1 NLRC5 GBP5 TAP1 TLR1 PIK3R5 GZMA LPXN FAM26F SLAMF9 CCR5 PTPRC FYB APOBEC1 CYP2E1 LACC1 OAS2 SIGLEC1 CH25H PSMB8 CD274 APOL6 DHX58 CTSK FBXO39 CMPK2 IFIT2 SNCA CHRDL1 HERC6 MLKL STAT2 PML ADAR NAMPT GBP2 NT5C3A PARP9 PARP12 ARC HSH2D XDH NOD2 SLC39A14 SOCS1 GPR35 ARG1 PPA1 MITD1 UBE2L6 TLR3 UBA7 GBP7 ACKR4 NAP1L5 LRAT IRF2 CLIC4 ZFP36 FOS PPP1CB DUSP1 DTX3L HPGD IRF9 PSMB9 PDGFRA LAMP2 RNF114 TAPBP ARRDC3 DDX3X TP53INP1 NPR3 RNASE6 THEMIS2 PICALM DEK SAMSN1 SLC12A1 OLFM4 WSCD1 TLR6 AICDA CMIP PLA2R1 TNFRSF14 PPP1R15B IRS2 CSRNP1 ZNFX1 PFKFB3 HAUS1 CTSO SIRT1 SOAT1 PTBP3 SGMS2 KHDRBS3 PDE4B TLDC2 ENC1 INSIG1 KLHL24 TIFAB ATAD2 SIK1 ZBTB22 TAP2 TNFSF8 S100A8 CASP1 IL15RA ZCCHC2 LGALS8 TRIM21 RNF31 USP25 TRIM56 ZC3HAV1 SPPL2A SELL RBM43 TDRD7 PCGF5 CCRL2 DLL1 MORC3 AZI2 ANKFY1 PER1 MCM4 SLC20A1 DDX60 ZBTB6 LGALS9 MX2 CASP7 SECISBP2L CRIM1 XPOT PRKACB RFWD3 COA7 FMNL2 CHST15 PATL1 SMCHD1 FAS PXK PARP3 PIK3AP1 GTPBP2 RAB8B CDA S1PR1 IL1RAP GPR17 APBA1 ISLR2 FANCA PRKG1 COL25A1 C4B RNF125 ITGA6 SEMA4D CCL7 USP33 KIT PIAS1 TIMP3 F2RL2 NEDD4 ACOD1 ZBTB38 BAK1 CGGBP1 MPP3 RIN2 EML4 ZBTB10 KCNJ2 GPCPD1 ERAP1 HERC4 TBC1D9 RAB6A CPNE3 PTPRJ NLRC4 CCN2 CPM GDA PER2 ECE1 SETD7 NCOA2 ID4 SENP7 LIN7C CHD6 GCNT1 SUZ12 PIK3C2A TTPA LEPR HK2 UBR1 SLC30A1 VCPIP1 ADGRG5 RANBP10 EXOC4 ZDHHC17 ABCB1B ABCA6 CBLB LATS1 CD2AP SYNJ1 BRCC3 PFKFB4 MED13L FNDC3A HIVEP1 RPGRIP1L STOML1 MIER3 KLHL4 TFCP2L1 SSX2IP VGLL3 CEP120 IFRD1 PHRF1 GFOD1 IDS MED13 KLHL23 TMEM2 TUT4 CPEB4 IGTP FCGR4 IFI47 PBLD2 AKR1C14 PBLD1 IFI209 H2-T24 SLFN1 ETNK1 TCF20 PLEKHA2 MBTPS2 DOCK4 MFAP3L TTYH2 SLC35G1 EXOC6B HELB AFF1 FCHO2 MOB1B FAM160B1 PPP2R5E EXOC6 ATAD1 MAPK1IP1L SPATA18 PRPF40A RAPGEF4 TMF1 S100PBP I830077J02RIK COL6A5 ACSS3 SNX27 PAK2 OPRD1 MTM1 PPP4R3B ADGRE4 FAM212A LRCH3 ANGPTL1 MTCP1 PAFAH1B2 AIRE KCTD12B ENSMAUG00000004249 ENSMAUG00000013430 ENSMAUG00000008373 ENSMAUG00000016439 ENSMAUG00000021711 ENSMAUG00000002714 ENSMAUG00000004543 ENSMAUG00000021045 ENSMAUG00000016573 ENSMAUG00000008425 ENSMAUG00000009569 GBP2B ENSMAUG00000020551 ENSMAUG00000011822 ENSMAUG00000009298 ENSMAUG00000014350 ENSMAUG00000010143 ENSMAUG00000001228 ENSMAUG00000008914 ENSMAUG00000012460 ENSMAUG00000009739 ENSMAUG00000010500 ENSMAUG00000004389 ENSMAUG00000001345 ENSMAUG00000004852 ENSMAUG00000005493 ENSMAUG00000000936 ENSMAUG00000014385 PGGHG ENSMAUG00000016905 ENSMAUG00000009872 ENSMAUG00000016348 ENSMAUG00000009831 CUNH19ORF66 ENSMAUG00000007782 ENSMAUG00000019942 ENSMAUG00000014013 ENSMAUG00000010948 ENSMAUG00000019682 ENSMAUG00000007175 ENSMAUG00000004294 ENSMAUG00000018493 ENSMAUG00000019177 ENSMAUG00000018991 ENSMAUG00000009900 ENSMAUG00000014158 CUNH19ORF12 ENSMAUG00000009126 ENSMAUG00000017592 ENSMAUG00000021919 ENSMAUG00000009998 ENSMAUG00000005814 ENSMAUG00000018005 SECTM1A ENSMAUG00000009345 ENSMAUG00000016894 ENSMAUG00000018352 CUNH5ORF24 ENSMAUG00000012428 ENSMAUG00000010998 ENSMAUG00000000364 ENSMAUG00000014837 ENSMAUG00000012286 ENSMAUG00000002626 ENSMAUG00000015914 ENSMAUG00000013702 ENSMAUG00000006063 ENSMAUG00000015933 ENSMAUG00000002564 ENSMAUG00000015154 ENSMAUG00000011408 ZFP654 ENSMAUG00000017499 ENSMAUG00000014004 ENSMAUG00000019502 ENSMAUG00000021371 D930020B18RIK ENSMAUG00000020409 CUNHXORF36 ENSMAUG00000005083 ENSMAUG00000004595 ENSMAUG00000010070 CUNH5ORF30 ENSMAUG00000019108 ENSMAUG00000020084 ENSMAUG00000016984 ENSMAUG00000016165 ZFP760 ENSMAUG00000007939 ENSMAUG00000000336 ENSMAUG00000014777 ENSMAUG00000000323 ENSMAUG00000010572 CUNH18ORF25 ENSMAUG00000009981 1110002E22RIK ENSMAUG00000013867 CUNH11ORF87 DNAJC16 ENSMAUG00000009645 ENSMAUG00000001298 ENSMAUG00000021694 ENSMAUG00000008075 ENSMAUG00000005359 ENSMAUG00000002119 ENSMAUG00000011188 CUNH10ORF10 GM28038 ENSMAUG00000003476 ENSMAUG00000017794 ENSMAUG00000012238 ENSMAUG00000010249 ENSMAUG00000009775 ENSMAUG00000001119 ENSMAUG00000009695 ENSMAUG00000015073 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 2 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 2 days post-infection. NBL1 PRKCZ SH3BGR CD34 APLNR TMPRSS2 MAP1LC3A CXCL5 HRAS THY1 NPC2 HSD11B2 FCER2 SIGMAR1 ADA CES2E SLC27A4 PABPC4 PRSS50 ACADVL CHP2 MGAT4B PTGER1 TIMM10 MOB2 ACADS PPIA PLP2 RHBDD3 ACBD4 LRRC61 DHRS1 ATF5 DDAH2 NT5DC2 KRT7 HES1 MAL MXRA7 FBXO36 SCGB3A1 RALGPS2 ATOX1 GPRC5A TACSTD2 KRT8 STARD10 ZBTB20 CHCHD10 TMEM246 TMEM109 TAGLN2 AQP3 TOMM40 UQCRC1 PRKCSH EMC10 LMNA EMP3 DHRS4 SMARCD3 CEBPA NREP NOL3 TMEM38A LGALS1 WFDC1 NDUFAF3 MPND ROGDI GALK1 MYDGF CLDN7 FAM20C MMP19 CDC20 SEMA6B SIGIRR GSTM1 CRIP2 G0S2 NCALD COL6A2 IGFBP3 KLF16 BAD HINT2 PKP3 CRB3 ELANE SPINT2 ADAP1 PLCD1 GJB3 EPN3 ANXA8 TMEM184A PAK4 LSR JAG2 SERINC2 RARG CLDN3 RHOD ARHGEF16 RSPO1 MAP2K3 SLC9A3R2 DHH TMEM88 BIN1 PWWP2B TRPV6 SCAMP4 NPEPL1 GLIS2 PHC2 LFNG ERF MXD3 CD3D FSBP CRMP1 CCL24 BPIFA1 FABP3 MB DNPH1 CDH16 TMEM143 TINAGL1 RASA4 TNNI1 CDH22 UCP3 LRFN4 GRASP TPPP3 RAMP2 CLIC3 SMAGP AGER SOX18 SFTPC S100A4 CRIP1 RPL10A SLC16A11 COX8A NDUFS3 ATP5D SH3BGRL3 JUND COX4I1 NDUFB11 EFNB1 ESAM FAM189A2 CA4 KRTCAP2 EVA1B ROMO1 NDUFV3 S100A16 SMIM22 TMEM259 LXN ELOVL1 TPRG1L NUDT16L1 GUK1 GLRX5 DBI NDUFB10 ECSCR CCDC85B DAD1 TSPAN18 TGFB1I1 SLC35E4 GJA4 TP53I11 NPDC1 FOXO6 IER5L BAMBI ATRAID UBE2M NQO1 BABAM1 SRM CKB SLC29A1 TUBB6 SCG5 HEBP2 ETFB TSEN34 LDHB SPSB3 LTC4S ID1 TMEM179 GAS2L1 TMEM139 SMIM1 ATP5E BTBD6 ANKRD9 VAMP5 MYLK2 FAM110A CSK SSNA1 CRACR2B PTMS RARRES2 CPNE2 FXYD2 SFXN3 BBOX1 IDH2 CKAP4 UCP2 BOP1 SEMA3G RASL10A MRGPRF VAT1 MYL6 NRGN TAF10 UQCR11 R3HDM4 CDC42EP2 SCTR IL1RL1 APOE CRLF1 NKAIN4 CXCL12 PRDX2 TNFRSF25 ZDHHC1 TYRO3 TRAPPC1 EXOSC7 MYCN RNF5 GDF5 UXS1 SPRYD3 FKBP2 PHGDH SMPD2 HM13 NUDT8 SCNM1 DENND2A AIG1 ACAA2 AVPI1 GSTA4 TPCN1 MRPL52 TSPAN1 OPA3 THBS3 CDK10 SPNS1 TBL3 COMTD1 NOXO1 LRP3 MAZ STX1B METRN FHL3 DAPK3 SLC39A7 TIMM13 VSIG2 ARHGEF15 SGSM2 FXYD6 PDGFA PRICKLE3 RPS6KA4 TMEM79 CRYBA4 SLC51B TMPRSS9 VWA1 HID1 SRD5A3 PTP4A3 TMEM254 ATP2A3 CPT1B GSTM3 S1PR4 SLCO3A1 IMPDH1 MAT1A HSPB2 BIRC7 MRPL4 MMP15 TXNRD3 CRTAP RNASEK HSD3B7 SELENOW MGST3 TIMM17A AK1 MRPL23 SDSL JOSD2 TOMM7 DNLZ SLC25A1 NTHL1 GAMT MYL6B RHOF ANXA6 CPE PPP1R3C SPRN DGCR6 CLEC11A RAD9A MACROD1 NAA38 ECI1 PRR7 MOSPD3 RFNG FAM166A MRPL43 CBX6 PRAG1 PYURF APBB1 KIF1C GSTM6 SCRN2 GRCC10 MED9 MRPS16 GIT1 FBXL15 FMNL3 DUSP14 MMP28 REM1 FAM110D LOXL1 SHISA4 RASL12 TSPAN9 TIE1 ELOF1 AES YBX2 GPR153 PODXL2 OCEL1 PLLP SDHAF1 SH3BP5L MPPED2 CHMP6 SPATA2L POMGNT1 PTOV1 SPSB2 POLR2I GPRC5B RCN3 TESK1 ENDOV EVI5L ZNF768 TMEM59L MYO1H SULT5A1 SH3D21 NENF POLR2D MRPS18B SMIM11A HSD17B8 PLEKHG5 BSCL2 SMIM4 CHST12 TMEM42 MFAP2 METTL24 C1QTNF9 ZFP296 TTC7 WRAP73 ADSSL1 TMEM198B SCARF2 CHCHD5 TMEM250 TEDC1 TMEM102 NXPH4 FAM221A GRIK1 COPZ2 TMEM190 CRTAC1 GRIN3B SLC7A4 EMID1 P3H4 METTL2A OVOL3 CNPY4 ENSMAUG00000014380 ENSMAUG00000016341 ENSMAUG00000002685 ENSMAUG00000021069 ENSMAUG00000005174 MFSD7A CD209E ENSMAUG00000016958 ENSMAUG00000016015 ENSMAUG00000002343 ENSMAUG00000011729 ENSMAUG00000008077 ENSMAUG00000017818 ENSMAUG00000017070 ENSMAUG00000001063 ENSMAUG00000001910 ENSMAUG00000019145 ENSMAUG00000021183 ENSMAUG00000018753 ENSMAUG00000006567 ENSMAUG00000009532 SCX ENSMAUG00000001932 DPYSL4 CYP21A1 GKN3 CUNH9ORF142 ENSMAUG00000013812 ENSMAUG00000000403 ENSMAUG00000003216 ENSMAUG00000013078 ENSMAUG00000004637 TRP53I13 REG3GAMMA ENSMAUG00000007948 ENSMAUG00000017366 ZNF48 ENSMAUG00000009110 ENSMAUG00000015180 4-SEP ENSMAUG00000017078 ENSMAUG00000020207 ENSMAUG00000009260 ENSMAUG00000022119 ENSMAUG00000015288 PCDHB18 1700020L24RIK CUNH4ORF19 RFLNB ENSMAUG00000000146 ENSMAUG00000005884 CUNH19ORF60 ENSMAUG00000003456 ENSMAUG00000019004 SNORD23 CUNH11ORF91 ENSMAUG00000011346 ENSMAUG00000021094 ENSMAUG00000003420 ENSMAUG00000007040 ENSMAUG00000015724 ENSMAUG00000015088 H1F10 ENSMAUG00000017210 FICD ENSMAUG00000021748 ENSMAUG00000006843 ENSMAUG00000016756 ENSMAUG00000000038 CUNH6ORF89 ENSMAUG00000000509 ENSMAUG00000018177 LBHD2 ENSMAUG00000016907 ENSMAUG00000013096 Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 3 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 3 days post-infection. PPBP UHRF1 FGL2 CCL2 CCL5 CMA1 EGR1 NMI ICOS DDX58 CXCL10 RNF2 CTLA4 TOR1AIP1 LAP3 XIAP F5 POLA1 CUL2 FASLG STAT1 IFITM2 B2M EIF2AK2 TDP2 RARS ITGA4 ISG15 SCN3B MX1 G3BP2 PLEKHA7 PLSCR2 CERKL TNFSF10 HLF RICTOR PRDM1 PRSS23 CCL8 ABCA1 UNC93B1 ENPP4 PARP10 LGALS3BP RNASEL TOR3A BST2 SLAMF8 CCNA2 LMO2 CLSPN LMNB1 NEK2 TMEM106A IFI44 SPAG5 MSR1 BUB1B MS4A4A DLGAP5 MAFB C1QB EPSTI1 TRPM2 CCR2 MERTK PTPRO SPATS2L MKI67 CLEC12A ANGPTL6 SLC2A6 MPEG1 ITGA2B ATF3 IRF8 FZD4 RAP1A CBFB HELZ2 MEFV KLRD1 CD48 ARHGAP11A RSAD2 GPR65 IDO1 IL10RA MIS18BP1 IRF7 NKG7 ZBP1 AOAH NLRC5 GBP5 TAP1 TLR1 HELLS IL2RB PIK3R5 GZMA LPXN FAM26F DEPDC1 NCAPG2 SLAMF9 CCR5 PTPRC FYB INCENP RAD51AP1 APOBEC1 ACKR1 LACC1 OAS2 SIGLEC1 PSMB8 CD274 APOL6 DHX58 CTSK FBXO39 GPR141 CMPK2 IFIT2 MMP12 HERC6 MLKL STAT2 PML ADAR NAMPT TIFA GBP2 NT5C3A PARP9 PARP12 ARC HSH2D XDH SOCS1 PPA1 MITD1 UBE2L6 TLR3 DRD4 UBA7 GBP7 IRF2 PSME1 HMGCS1 DTX3L HPGD IRF9 PSMB9 LAMP2 RNF114 TAPBP ARRDC3 DDX3X TP53INP1 GIMAP4 RNASE6 THEMIS2 IVNS1ABP VPS26A DEK SAMSN1 SLC12A1 P2RY12 OLFM4 GP6 TNFAIP3 AICDA PLA2R1 TNFRSF14 BHLHE40 ZNFX1 PFKFB3 RRM1 BFAR CTSO FAM107B USP1 KPNA3 SNX10 GNA13 SOAT1 VAV3 PTBP3 KHDRBS3 TMEM47 CKAP5 TLDC2 KRCC1 TIFAB ATAD2 CDCA7 NEDD1 RAP1GAP2 TAP2 CIITA NCR1 PRF1 TNFSF8 CASP1 IL15RA ZCCHC2 TRIM21 RNF31 GSDMD USP25 ZC3HAV1 SPPL2A SELL RBM43 TDRD7 PCGF5 CCRL2 DLL1 MORC3 NRARP PIK3CG PIKFYVE CD38 LBR CXCL11 GPR101 MCM4 DDX60 TIA1 ZBTB6 LGALS9 MX2 CASP7 SECISBP2L PSTPIP2 FNIP1 RFWD3 COA7 RFX7 HOMER1 CHST15 BAZ1A SMCHD1 FAS PARP8 PXK PIK3AP1 RAB8B XPO1 GZMB LPAR6 IL1RAP AIM2 ITGB3 ISLR2 CD80 FANCA COL25A1 HS3ST3B1 C4B TLR8 RNF125 ITGA6 CCL7 IDI1 LILRA5 KIT ROS1 F2RL2 FAM111A SC5D ACOD1 BAK1 CYLD RNF13 FUNDC2 ARL8B CAPZA1 CGGBP1 SUV39H2 EML4 GPCPD1 ERAP1 HERC4 MIER1 DAPP1 TBC1D9 CPNE3 NLRC4 APLN ZBED4 LRRN1 CACUL1 PLD5 CDC27 SUZ12 SMC4 PIK3C2A ABCA9 TARDBP VCPIP1 SNX13 IL13RA1 RFC1 ADGRG5 CLEC9A GOSR1 CYP39A1 TUBB1 ABCB1B ABCA6 SLC17A2 SLC23A2 UGCG WWP1 CD2AP TEF TOPBP1 CSGALNACT2 SYNJ1 BRCC3 FNDC3A RPGRIP1L MFSD2A STOML1 MIER3 KLHL4 STK17B PHRF1 H2BC18 RESF1 PATL2 IGTP FCGR4 IFI47 PBLD2 AKR1C14 PBLD1 IFI209 H2-T24 DOCK10 SLFN1 XRN2 SCD1 PLEKHA2 PRPF4B EDA2R HNRNPH3 SNX16 MBTPS2 RAD18 TTYH2 ANKIB1 SNAP23 PDP2 FKTN KIF4 HELB SCD2 JPT2 FAR1 PPP2R5E EXOC6 ATAD1 MTMR6 MAPK1IP1L DNAJC13 PRPF40A KDM1B RAPGEF4 COL6A5 FAM98B SNX27 PAK2 MTM1 PPP4R3B PTPRG DACH1 KITL ADGRE4 KLRB1F 6-SEP FAM212A POT1B MTCP1 PAFAH1B2 AIRE RHBDL2 KCTD12B ENSMAUG00000004249 ENSMAUG00000013430 ENSMAUG00000008373 ENSMAUG00000016439 ENSMAUG00000021711 ENSMAUG00000002714 ENSMAUG00000004543 ENSMAUG00000021045 ENSMAUG00000016573 ENSMAUG00000008425 ENSMAUG00000009569 GBP2B ENSMAUG00000020551 ENSMAUG00000011822 ENSMAUG00000014350 ENSMAUG00000010143 ENSMAUG00000001228 ENSMAUG00000008914 ENSMAUG00000012460 ENSMAUG00000009739 ENSMAUG00000010500 ENSMAUG00000004389 ENSMAUG00000001345 ENSMAUG00000004852 ENSMAUG00000005493 ENSMAUG00000000936 ENSMAUG00000014385 PGGHG ENSMAUG00000016905 ENSMAUG00000009872 ENSMAUG00000016348 CUNH19ORF66 ENSMAUG00000007782 ENSMAUG00000014013 ENSMAUG00000010948 ENSMAUG00000019682 ENSMAUG00000007175 ENSMAUG00000004294 ENSMAUG00000018493 ENSMAUG00000019177 ENSMAUG00000018991 ENSMAUG00000009900 ENSMAUG00000014158 CUNH19ORF12 ENSMAUG00000009126 ENSMAUG00000017592 ENSMAUG00000021919 ENSMAUG00000009998 ENSMAUG00000018005 ENSMAUG00000012848 CUNH1ORF54 ENSMAUG00000001962 ENSMAUG00000006550 ENSMAUG00000010592 KLRE1 SECTM1A ENSMAUG00000009345 ENSMAUG00000016894 ENSMAUG00000018352 ENSMAUG00000002746 ENSMAUG00000000364 ENSMAUG00000008083 ENSMAUG00000021786 ENSMAUG00000012286 ENSMAUG00000020019 ENSMAUG00000013702 ENSMAUG00000015933 ENSMAUG00000002564 ENSMAUG00000015154 ENSMAUG00000017499 ENSMAUG00000014004 CUNHXORF36 ENSMAUG00000004595 CUNH5ORF30 ENSMAUG00000019108 ENSMAUG00000020084 ENSMAUG00000007939 ENSMAUG00000014777 ENSMAUG00000000323 ENSMAUG00000010572 CUNH18ORF25 ENSMAUG00000013867 ENSMAUG00000008075 ENSMAUG00000005359 ENSMAUG00000002119 ENSMAUG00000003476 ENSMAUG00000010249 ENSMAUG00000009775 ENSMAUG00000001119 ENSMAUG00000009695 ENSMAUG00000015073 ENSMAUG00000011148 ENSMAUG00000016154 ENSMAUG00000018172 CLCA3B ENSMAUG00000016687 ENSMAUG00000018475 ENSMAUG00000015313 ENSMAUG00000000162 ENSMAUG00000018775 ENSMAUG00000001856 ENSMAUG00000000443 ENSMAUG00000011704 ENSMAUG00000009451 ENSMAUG00000001991 ENSMAUG00000016595 ENSMAUG00000002837 ENSMAUG00000000191 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 3 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 3 days post-infection. STMN4 PIK3R2 NBL1 GIF PRKCZ APLNR MAP1LC3A UBXN6 PPP2R1A CKM NPC2 ST14 KCNQ1 HSPB1 ADA TCN2 KIAA2013 COL4A2 ACADVL HGS CYB5R3 MFGE8 MGAT4B EPS8L2 POR PEPD ETV5 ACADS SCARB1 FCGBP PLP2 FAH PCSK7 LRRC61 ATF5 DDAH2 PLEKHO1 SDC1 KRT18 NT5DC2 KRT7 MAL MXRA7 AQP5 FBXO36 SCGB3A1 ITGA10 SLC25A4 KRT19 NDRG2 GPRC5A TACSTD2 LCN2 KRT8 STARD10 TMEM246 TMEM109 ATP1A1 AQP3 TOMM40 PRKCSH GSN AP1M1 LRP10 GPD1 ITGB5 LMNA SLC16A3 RHBDD2 PPP1R12C GBGT1 CEBPA HADHA MARVELD1 TMEM38A ACVRL1 WFDC1 GALK1 ADAMTS2 CLDN7 MMP19 SEMA6B CRIP2 COL18A1 PBXIP1 IGFBP3 SLC2A4 BAD SERPINF1 SPINT2 ITGB4 TMC4 CYB561 LAMB3 ANXA8 LSR JAG2 SERINC2 KRT80 MYH14 CLDN3 IRF6 SLC52A2 EPHB4 HR RHOD ARHGEF16 PYGO1 NKD2 EGFL6 FGF1 PORCN SLC9A3R2 MESP1 NPEPL1 TMEM63B PHC2 DDR1 AKT1S1 ERF DHRS7C TNNT2 CASQ2 BPIFA1 MYH6 TNNI3 FABP3 MYBPHL MYH8 MYBPC3 CSRP3 MB CKMT2 MYL4 NTRK2 SFTPB LGI3 HMGCS2 IGFBP6 TINAGL1 TNFRSF12A TNNI1 ANGPTL4 UCP3 ACTC1 PSENEN COX6A2 TNNC1 BMP6 GRASP CRYAB FAM129B THRA TPPP3 RAMP2 AGER SFTPC SLC16A11 SERPINE2 TAGLN ATP5D S100A6 JUND HCFC1R1 HADH OAZ1 EFNB1 ESAM FAM189A2 CA4 KRTCAP2 EVA1B S100A16 KLHDC3 TMEM259 VWF ELOVL1 TPRG1L TNNI2 GUK1 USHBP1 GLRX5 FXYD1 HIGD2A CCDC85B DAD1 ANK1 TSPAN18 TGFB1I1 COL13A1 PADI4 SLC35E4 PGLYRP1 SPON2 GJA4 NPDC1 UNC5B DMTN GPX3 FOXO6 UBE2M SLC29A1 SSSCA1 MANBAL YIPF3 SCG5 HEBP2 PFKM DECR1 ETFB TSEN34 SPSB3 BTD LTC4S CNN1 LRRC3 TMEM179 GAS2L1 TMEM139 SMIM1 REEP1 ODF3B VAMP5 MYLK2 ZMYND10 ADPRHL1 TCAP CRACR2B IRX1 PTMS RARRES2 CPNE2 TRNP1 NPW MTCL1 CRISPLD2 NRTN PNKP LAMB2 SCGB1C1 UCP2 SEMA3G TAC4 MLF2 SH3BP4 RASL10A ALDH2 MYL9 R3HDM4 ITGAD ACTA2 SCTR APOE CCDC184 CRLF1 NKAIN4 C1QTNF1 CXCL12 ZDHHC1 TYRO3 RNF5 UXS1 SPRYD3 CD82 EEF1A2 PHGDH HM13 VTN NUDT8 CCDC92 AUP1 ACAA2 GSTA4 ABHD8 TPCN1 DDX54 IRF2BP1 TSPAN1 LIN37 THBS3 ALDOC SUSD2 SPNS1 TBL3 PINK1 TRIP6 HDAC5 NOXO1 LRP3 P4HTM ATP9A KLHDC7A MFNG PROK2 HSPB6 PARVB CYC1 DAPK3 SLC39A7 TIMM13 GAS6 FXYD6 PRICKLE3 RPS6KA4 UNC45A SLC51B SCNN1B TMPRSS9 VWA1 HID1 TMEM254 SLC19A1 CPT1B POLR2F ASIC3 FUT1 SMPD5 S1PR4 SLCO3A1 IMPDH1 ACSM5 CAV3 HSPB2 IL11RA POLDIP2 MMP15 HSPB7 PRDX6 TXNRD3 CRTAP PLOD3 RNASEK SELENOW TEAD3 AK1 CLDN23 ADM2 HS6ST1 CTXN1 PGAP3 RHOF ANXA6 FADS3 PDK2 CLEC11A MACROD1 EEFSEC BOK RFNG SNTA1 TMEM161A ECH1 HPS6 LMF2 CAVIN3 USP20 PYURF KIF1C GSTM6 SUOX HDAC11 GRCC10 FCMR DNAJC1 SCN1B RAB3D REM1 FAM110D SHISA4 RASL12 TSPAN9 TIE1 DES ELOF1 FBXW8 AES TMEM120A PODXL2 OCEL1 FAM234A PLLP IGKV7-33 SH3BP5L PGS1 HHATL DCTN1 POMGNT1 PTOV1 LYNX1 FAM89B POLR2I GPRC5B PALM TESK1 SLC22A17 ENDOV FBXO44 OGFOD2 EVI5L TMEM59L SULT5A1 PPP1R35 NSMCE2 C1QTNF4 SMIM11A HSD17B8 PLEKHG5 MORN1 MYLK3 SMIM4 KCNK3 P3H2 CHST12 KAT14 CLDN11 MFAP2 CFAP73 PACRG IFT172 C1QTNF9 MFSD4A TTC7 PCBP4 COQ8A ADSSL1 SYNE4 TMEM250 TEDC1 ANKRD65 TMEM102 RANBP3 GRIK1 SYNDIG1 CD248 CCDC102A TMEM190 SLC7A4 EMID1 OVOL3 ENSMAUG00000014380 ENSMAUG00000016341 ENSMAUG00000002685 ENSMAUG00000005174 CD209E ENSMAUG00000021154 ENSMAUG00000006120 ENSMAUG00000011729 H2AJ ENSMAUG00000001063 ENSMAUG00000021779 WASHC1 ENSMAUG00000007215 ENSMAUG00000001932 ENSMAUG00000013812 ENSMAUG00000004637 ENSMAUG00000007948 ENSMAUG00000017366 ENSMAUG00000009110 CUNH19ORF60 ENSMAUG00000019004 ENSMAUG00000015724 ENSMAUG00000017210 ENSMAUG00000018177 LBHD2 NMRK2 ENSMAUG00000014686 ENSMAUG00000014877 ENSMAUG00000014450 CUNH9ORF24 ENSMAUG00000014861 GM266 ENSMAUG00000016459 ENSMAUG00000020594 ENSMAUG00000000685 C030006K11RIK ENSMAUG00000008691 ENSMAUG00000021197 ENSMAUG00000020834 CUNH10ORF53 ENSMAUG00000016726 ENSMAUG00000014689 ENSMAUG00000005989 ENSMAUG00000016543 ENSMAUG00000016990 ENSMAUG00000018955 MISP3 MTLN RAPSN ENSMAUG00000010125 SLN ENSMAUG00000020615 MIR208B CUNH20ORF85 CUNH9ORF16 ENSMAUG00000020514 MIR208A SNORD37 CFAP126 MUSTN1 FADS2B Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 5 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 5 days post-infection. UHRF1 IL6 GDF15 CCL2 CCL5 UBD PDCD1 NMI DDX58 CXCL10 CTLA4 GTF2F2 LAP3 PGC GGT1 IFNG NLRP6 HMOX1 BZW2 SELENOS SPATA19 PSMC6 FASLG STAT1 IFITM2 B2M SFN EIF2AK2 TMEM173 RARS ISG15 PAICS IL10 MX1 UBE2E1 ATP6V1B2 PLSCR2 TMEM86A PSMA2 MT2A KRT18 KRT17 IGSF6 CKS2 CCL8 ISG20 LCN2 AIF1 UNC93B1 LAIR1 C1QC LGALS3BP THBS1 PARVG TOR3A C1QA EMILIN2 CYBA DOK2 BST2 SLAMF8 TIMP1 TOP2A TK1 C3AR1 LMNB1 NEK2 SHCBP1 TMEM106A NUF2 SEC11A SPAG5 MSR1 FKBP5 KIF2C MS4A4A DLGAP5 GPNMB MAFB BIRC5 C1QB CD163 SCIMP EPSTI1 KIF15 LGALS3 CCR2 SNX8 HP NTSR1 MTHFD2 CLEC12A CST7 CCL4 SLC2A6 PIK3IP1 BATF CCNE1 OSM CLDN4 CARD14 SLC7A5 B3GNT3 IBSP ATF3 IRF8 UPP1 PSMA3 ZAP70 CXCR3 CD48 RSAD2 GPR65 GRAP2 SLC37A2 CD69 IDO1 IL10RA IRF7 RGS1 NKG7 ZBP1 AOAH RAD51 IL18BP LCP2 DUSP2 PYCARD SH2D1A GBP5 TAP1 TLR1 CTSW MS4A6A HELLS HCST GPR84 CLEC5A LCK GZMA TACC3 CD3D LPXN FAM26F XCL1 TNFRSF18 SLAMF9 STAT4 CD3E CCR5 PTPRC FYB CD2 CLEC7A VAV1 KCNN4 TBX21 GZMK LAG3 COTL1 CTSS RAD51AP1 GPR171 APOBEC1 FCER1G CD84 TLR7 LRP8 SIGLEC1 PSMB8 CD274 APOL6 KCNJ10 CCR1 DHX58 CTSK IL1RN CMPK2 IFIT2 EVI2A CLEC4E PTAFR FGL1 HERC6 MLKL LGMN SOCS3 TREM1 NAMPT TIFA GBP2 MCOLN2 NT5C3A GLIPR2 PARP9 HSH2D XDH SOCS1 GPR35 ARG1 MITD1 UBE2L6 GBP7 PSME1 PSME2 DTX3L IRF9 PSMB9 GNG10 CTSH RNF114 NUPR1 ABRACL RGCC TYROBP IFI30 CRELD2 MPC2 RNASE6 THEMIS2 SAT1 RPS27L PIN4 DEK SAMSN1 LST1 SLA TLR6 TNFAIP3 AICDA TNFRSF14 DUSP5 CSRNP1 MAGT1 ZBTB8OS PSMA4 RRM1 PTTG1 RPA2 VMP1 NOP58 PCNA UCHL5 VRK1 NUP37 SSR4 FAM96A PSMA1 NELFE PSMD14 SNX10 EMC9 SDF2L1 SOAT1 NUDT9 TLDC2 RIPK3 TIFAB CDCA7 RPA3 TAP2 NCR1 P2RY13 NAGPA CLEC4F TLR2 CASP1 IL15RA CD40 TRIM21 CREM GSDMD RBM43 CCRL2 TNFRSF4 RHOH CD38 CXCL11 CTSV TMA16 MCM4 DDX60 METRNL TFPI2 GBX2 RNF19B TNFSF13B MX2 PSTPIP2 COA7 CSTB B3GALNT1 SOD2 FAS PIK3AP1 BLVRB SERPINB1 CDA CD53 GZMB SNRPB2 KLRK1 PLEK KCNE3 ADAM8 CD68 CCL12 CCL3 CD209A CCL7 RTCA FUT7 CD300A FGR NCF2 F2RL2 NUDT5 PITPNA TNFAIP8 ACOD1 BAK1 HMBS SPP1 UBE2F B3GNT2 RAB3IL1 FFAR2 PLA2G4A FGA PMF1 MCTS1 TFEC DAPP1 NASP SPHK1 NPL SMC4 GALNT6 PCLAF CISD2 UGCG MCM3 PSMA5 STARD5 DUSP12 H2-AA SLBP RMI2 TXNL4B MRPL3 STK17B SNX24 CNP PHRF1 RFC3 SLC35F6 LSM5 TMEM134 IGTP H2-AB1 FCGR4 SAA3 PBLD2 IFI209 IQGAP2 TTYH2 GTF2A1 PTPMT1 FAM46C H2-EA-PS PRKCQ RNF217 RDH10 PLAAT3 RBMX2 PTRH2 EIF2S2 HTR7 I830077J02RIK TCTEX1D1 CEPT1 NKAIN1 RAB19 TCTEX1D4 TM4SF19 PHYHD1 CHIL1 H2AX CCDC28B WDFY2 AIRE TIGIT RHBDL2 ENSMAUG00000004249 ENSMAUG00000013430 ENSMAUG00000016439 ENSMAUG00000021711 ENSMAUG00000002714 ENSMAUG00000004543 ENSMAUG00000021045 ENSMAUG00000008425 GBP2B ENSMAUG00000020551 ENSMAUG00000008633 CUNHXORF21 ENSMAUG00000010143 ENSMAUG00000012460 ENSMAUG00000009739 ENSMAUG00000010500 ENSMAUG00000001345 ENSMAUG00000004852 ENSMAUG00000005493 ENSMAUG00000000565 ENSMAUG00000018779 ENSMAUG00000000936 ENSMAUG00000014385 D16ERTD472E PGGHG ENSMAUG00000016905 ENSMAUG00000000846 ENSMAUG00000009872 ENSMAUG00000007782 ENSMAUG00000019942 ENSMAUG00000010948 ENSMAUG00000021205 ENSMAUG00000007175 ENSMAUG00000004294 ENSMAUG00000018493 CUNH15ORF48 FAM241A ENSMAUG00000014158 CUNH19ORF12 ENSMAUG00000009126 ENSMAUG00000017592 ENSMAUG00000021919 ENSMAUG00000009998 ENSMAUG00000010003 MIR147 ENSMAUG00000018005 ENSMAUG00000012848 CD209C CD209E ENSMAUG00000001962 ENSMAUG00000007111 ENSMAUG00000006550 ENSMAUG00000010592 KLRE1 SECTM1A ENSMAUG00000009345 ENSMAUG00000016894 ENSMAUG00000018352 ENSMAUG00000020100 ENSMAUG00000010614 ENSMAUG00000000797 ENSMAUG00000020091 ENSMAUG00000021786 ENSMAUG00000000966 ENSMAUG00000008799 ENSMAUG00000005083 ENSMAUG00000004595 ENSMAUG00000010572 ENSMAUG00000002119 ENSMAUG00000003476 ENSMAUG00000015073 ENSMAUG00000016154 ENSMAUG00000018475 ENSMAUG00000020943 ENSMAUG00000020137 ENSMAUG00000014530 ENSMAUG00000008923 ENSMAUG00000005737 ENSMAUG00000012467 ENSMAUG00000020122 ENSMAUG00000004376 ENSMAUG00000007045 CFAP161 ENSMAUG00000011094 ENSMAUG00000009213 ENSMAUG00000020771 ENSMAUG00000017054 ENSMAUG00000018483 ENSMAUG00000000784 ENSMAUG00000007408 ENSMAUG00000000153 ENSMAUG00000015711 ENSMAUG00000009903 ENSMAUG00000016149 ENSMAUG00000019488 ENSMAUG00000001668 ENSMAUG00000015991 ENSMAUG00000021387 ENSMAUG00000008940 ENSMAUG00000015397 MCUB ENSMAUG00000013218 ENSMAUG00000007808 ENSMAUG00000010231 ENSMAUG00000018261 ENSMAUG00000004648 ENSMAUG00000021252 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 5 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 5 days post-infection. GNA11 ADAMTS1 SPTB SLC5A2 APLNR CKM MACF1 MYO1D ABL1 COL4A1 XPNPEP2 PRRC2B COL4A3 MPZL1 COL4A2 VSTM4 NCKAP5 CYB5R3 FBN1 AKAP8L ZNF503 CREBL2 NEO1 KDR PARP16 NBEA OLFML2B ADCY2 MAP6 ADGRL2 FZD6 TJP1 ANK3 TMEM94 RIPOR1 SH3TC1 PIP5K1C RGS12 NDST1 ADGRE5 ITPKB ARHGAP31 NREP STARD13 WFDC1 UACA SMTN PRRT4 CDC42BPA ARHGAP23 LTBP4 MYH11 LAMA2 COL18A1 PTPRS COL6A2 IGFBP3 TUFT1 COL1A1 MMP11 PKD1 MAPT ABCG1 FGFR1 NECTIN1 AGRN SREBF1 BCL9L LAMB3 JUP CEP170B RARG EPHB4 HR ITPR3 FZD1 CLSTN1 PRICKLE1 EDNRB NAV2 NKD2 NR2F2 ARHGAP1 HERC2 BMP1 PTPRU TMEM63B MGRN1 ARHGAP35 ULK1 PRR12 DHRS7C RYR2 MYH6 TNNI3 MYBPHL MB CKMT2 ALAS2 STON1 RASA4 ITGA8 EPHA1 ACTC1 DPYSL2 SHANK3 TNS1 CDH5 CYTH3 TNNC1 BMP6 THRA CYYR1 BGN ST5 PTPRB SOX18 TJP2 NPNT VEGFA SPECC1L MYH10 LTBP3 FHL1 SH3PXD2A EFNB1 CHST1 RTKN2 MYLIP VWF KIF26A MEGF8 RGS5 COL6A3 MFHAS1 TSPAN18 NTRK3 ADAMTS17 AOC3 LDB3 PLD2 ADAMTS10 ARHGEF25 EGFLAM MRC2 EDNRA SPON2 UNC5B BCORL1 DMTN ADRA2A SKI SUSD5 MGLL KCTD9 PFKM FOXF2 SLCO2A1 RXFP1 SYT13 LTC4S KCND1 AOC2 MN1 NEURL1B PHYHIPL ROR2 TCAP CDC42BPG BTBD2 CASS4 MTCL1 AFAP1L2 FAM171A1 LAMB2 PLEKHA6 TULP4 SEMA3G TPRA1 SH3BP4 SLC2A10 IRS1 GALM SERPINA1 DYSF EFS SLC25A42 HEYL ACTA2 DOK7 LMOD1 DENND3 CHST2 LMCD1 CDC42EP2 PDLIM3 XYLT1 FADS2 SCTR PAMR1 LAMA3 KANK4 COL12A1 ADAM12 MMP2 CDH13 ANO1 ATP1B2 RNF144A LRRC4B WSCD2 ITGA9 C1QTNF1 PYGM ALPK3 AMDHD1 CXCL12 SCUBE3 RHBDL3 NRXN2 ANGPT2 MASP1 TYRO3 CD93 TBX2 RECK POSTN ARRB1 VTN DENND2A TPCN1 KIRREL MPP3 KIF13A FLT4 THBS3 SUSD2 PDE1A OBSL1 MEGF6 FAT1 HDAC5 PHLDB1 NCOR2 DSCAML1 ADCY5 EPHB3 PXDN NFATC4 PCDH12 KANK2 AMOTL1 PDGFRB XPC ABLIM3 CTTN ARHGEF15 DOCK6 PCDH1 RPS6KA2 DCHS1 ARAP3 PLN PTK7 FAM13C PLXNB1 SEMA6A PLXNA1 MAGI1 MAGI3 ZBTB4 SIPA1L3 HID1 PTPRF CDH11 RUNX1T1 TSC2 PDGFB TMEM119 LRSAM1 NOTCH3 MYO1C SLC19A1 CACNA1C CAMK2G ATG13 PEG3 PCDH17 FBXO32 MAP1A CARD10 SCARF1 ADAMTS13 TRPC6 SCARA3 ZNF641 CAMK2A MPP2 SLCO3A1 LAMA4 COL5A1 SLC16A2 SLC22A15 MMP15 PLCG1 ANTXR1 NYNRIN TCAF1 PDZD2 DLC1 BAHCC1 CNKSR3 HS6ST1 CSNK1E KIF3C AFAP1 LTBP2 FNDC4 ENDOD1 VANGL2 FAT4 PPP1R3C ZNF608 RASGRF2 APBB2 CCBE1 TSHZ1 SVIL MAP4K2 SPNS2 PLPP3 HSPG2 PALLD ZNF516 GRIP2 SIPA1L2 TBC1D16 USP20 ATP11A TTC28 SLIT2 ST3GAL2 SARDH FRAS1 ADCY9 DAG1 SVEP1 SLC12A4 LRP4 MMP28 FMOD CDR2L REM1 SLIT3 NGFR MRVI1 RASL12 COL5A3 SPEG SLC4A3 TIE1 IL17RE ARHGAP42 PRR36 RGL3 ARHGEF40 ADGRL1 AATK PHLPP1 ATP2B4 P2RX1 EPN2 CADM1 TNXB RTL6 MTSS2 TBX5 ATN1 KCNC3 CROCC PPP1R26 SOGA1 MINK1 ADCY3 NEK8 CARNS1 PALM PIEZO2 SLC22A17 ENDOV MMRN2 EVI5L TMEM8B KLHL17 COL6A5 SULT5A1 SH3RF3 GNAO1 CHN1 SDK1 PITPNM3 IQSEC1 PLEKHG5 VWA5B1 ARHGAP28 FRRS1L ARMCX4 NRBP2 KCNK3 TBX4 PHEX NMNAT2 FREM1 SNED1 MAML3 CUL7 DUSP27 MARF1 CBFA2T3 D630003M21RIK SV2A FAM212B PKNOX2 ADGRA2 EFCC1 ADAMTSL5 GFRA2 TRIM3 KRBA1 MAP3K12 GUCY1B3 IGSF10 SCARF2 PAPPA2 PRELP DAAM2 PCDHGA8 CNTN2 SYNDIG1 CD248 STARD8 SSPO CNTN3 ENSMAUG00000000459 ENSMAUG00000017772 ENSMAUG00000009219 ENSMAUG00000020573 ENSMAUG00000002343 ENSMAUG00000015247 ENSMAUG00000008611 ENSMAUG00000020614 ENSMAUG00000017174 ENSMAUG00000016984 CYP21A1 ENSMAUG00000018177 ENSMAUG00000013096 MIR208B MIR208A ENSMAUG00000005623 ENSMAUG00000015320 ENSMAUG00000022058 ENSMAUG00000010804 ENSMAUG00000018984 ENSMAUG00000000871 ENSMAUG00000011612 GATA5 ENSMAUG00000017829 GALNT16 ENSMAUG00000006434 ARHGEF10 ENSMAUG00000017408 FIGNL2 ENSMAUG00000007530 ENSMAUG00000012588 ENSMAUG00000002079 ENSMAUG00000013283 ENSMAUG00000004145 DMRTC2 ENSMAUG00000014937 ENSMAUG00000010226 ENSMAUG00000015366 ENSMAUG00000005508 ENSMAUG00000003052 ENSMAUG00000007460 SSU2 CUNH16ORF58 ENSMAUG00000019672 LARGE1 ENSMAUG00000015384 ENSMAUG00000000456 ENSMAUG00000019908 KBTBD13 TMEM136 ENSMAUG00000002831 ENSMAUG00000021702 SHE ENSMAUG00000016988 CDCP3 ENSMAUG00000009225 ENSMAUG00000013880 Top 500 up genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 14 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 14 days post-infection. FOXRED2 CYP4F14 UIMC1 EPS8L3 NINL EGR1 SLC7A7 VIL1 SCN2B HOOK1 FBLN5 GNGT2 FN1 TM4SF5 CLEC4G RETSAT EPS8L2 NUP214 TTC38 FBP1 ESM1 CDAN1 IPP HES1 HLF NR4A2 UPK1B GALNT5 PTGFR TSTD1 INPP4B ABCA1 MEIS1 AADAT ARHGAP4 TMEM273 ACSS1 ITGAX SH3BP2 NRP2 HK3 FUCA2 ESPL1 GPNMB MYO7A IGLL5 JCHAIN TRIM71 KCNMA1 ESRP2 TOPORS EGR3 KLF2 BMP7 APLP1 KLF10 MMP11 CDH1 FAM20A CELSR1 SREBF1 SULT2B1 BNC2 NLK WNT6 FGF9 ATF3 SP7 SLC24A5 TCF7L2 BMP1 SLC45A4 FOSL2 CD226 LCP2 MS4A7 PPM1N CHIT1 TOX CCR5 CTSS MASTL SLC7A8 CYP26B1 CTSK C1R HEPACAM2 MAB21L3 NAV3 CPXM1 CCDC18 S100G TCIRG1 ARC HAS1 KLF4 CYR61 IER3 FOS IGFBP4 DUSP1 FABP5 EFEMP1 BCL6B ARRDC3 RBMS3 ERRFI1 CCNL1 IVNS1ABP NXF1 SLC12A1 CASP14 NR4A3 ASXL3 SYNGAP1 FNDC5 OLFM4 FLRT1 PCDHA9 MRC2 ADAMTS3 TENM2 ROBO4 GDPD1 GNA14 ANO7 PLA2R1 TBC1D30 FLRT3 DUSP5 ZIC2 CSRNP1 BHLHE40 FOSB ZBTB8OS HAUS1 GALNT7 CTSO NOL11 HMX1 FAM122B PLCD4 CDC25B TOB1 PDE4B HAMP PRR15 SALL1 CEMIP LRRN4 COL11A1 CDCA7 SIK1 MRAP2 CIITA WT1 BNC1 NDST3 NRARP PLK5 WDR86 CRB2 CD38 L3MBTL4 ALDH3A1 TRPM5 NID1 NTNG1 TMEM68 STX19 TRIML1 LRRC4C GPR101 MROH2A CFI ABAT CCDC77 LIPH PKHD1L1 CD83 PLK2 GRAMD1C CA9 KLRK1 GRIN3A ZFP82 TRIB1 LPIN1 CLK1 ZAN FOXB1 NR4A1 PLA2G4F APOE SCGN SCN2A SPRY4 KLHL33 TECTA SLC6A14 FANCA PRTG COL25A1 CLCNKB ACP5 SH2D6 C4B CACNA1E ITGA6 HPS1 HLX SIM2 CELSR2 SULF1 SEC16A SPP1 STXBP5L KCNJ15 ASAH1 ACKR3 XCR1 ZFHX2 KCNJ6 AACS PLK3 NLGN3 SMPD3 DSCAML1 SLC26A8 RSAD1 ITGA3 MCCC1 LRP2 SPOCK2 NPHS2 SEMA4G LRRN1 TMPRSS15 PLXNB1 GREB1 SALL4 PLD5 DCLK1 SMC4 SATB2 RAB33A DAPK1 SPG11 SPHK2 CPQ UBR4 ATG9B TLR11 TNFRSF13B LTBP1 ELAVL4 PON3 SULT1C2 MLANA TNC WSB1 UGCG LNX1 IRS3 TRPM6 ALDH1A2 SOX4 RASSF2 NEIL2 TEF PODN PRPSAP2 SHC3 HNMT H2-AA FLNB NEMP1 ATXN2L SRFBP1 CSPG5 MFSD2A LTBP2 KLHL4 DZIP3 ESPN DCAF17 ZBTB7C SSX2IP STK17B NHLRC3 ZNF703 UNC5A POLR3D TMEM265 ZNF248 RAI1 KLHL29 GABBR1 H2-AB1 KIF5B SCD1 EDA2R ARMCX3 SVEP1 SAMD5 5S_RRNA 7SK IDUA JAKMIP2 CENPJ NGFR IYD PDP2 RGL3 FAM222B XKR6 C1QL1 FAM46C ANKRD2 H2-EA-PS ZFP385A SCD2 LEFTY2 KCNC3 YLPM1 CORO7 PRPF40A RAB42 RAPGEF4 WASF3 S100PBP USP29 GABRB1 CPSF7 TRRAP MIP RFX4 OPRD1 SFI1 PLEKHG4 TCEAL9 NOL4L ANKRD61 SNAP91 SLC9A5 NEURL2 PHF8 EPOP TCTEX1D4 RMDN2 ABRA ATP2A1 CLEC4N TMEM108 MIR5125 WIPF3 KCNE2 ADAM33 SLC4A11 EDIL3 VRK3 SAMD3 L2HGDH KCNK12 CLDN22 DPP6 CYP26C1 ZPBP2 ENSMAUG00000001018 ENSMAUG00000007175 ENSMAUG00000016341 ENSMAUG00000005174 ENSMAUG00000010385 ENSMAUG00000006044 ENSMAUG00000005295 ENSMAUG00000002244 ENSMAUG00000005036 ENSMAUG00000007102 ENSMAUG00000007368 ENSMAUG00000009344 ENSMAUG00000019314 ENSMAUG00000016966 ENSMAUG00000008703 ENSMAUG00000017174 ENSMAUG00000019451 ENSMAUG00000000966 ENSMAUG00000020343 ENSMAUG00000002202 ENSMAUG00000012339 ENSMAUG00000015914 ENSMAUG00000005083 GM28038 ENSMAUG00000019004 ENSMAUG00000018775 ENSMAUG00000000443 ENSMAUG00000014450 ENSMAUG00000015397 ENSMAUG00000021252 ENSMAUG00000002831 ENSMAUG00000016988 MIR1839 CPZ ENSMAUG00000001525 ENSMAUG00000018113 ENSMAUG00000009467 ENSMAUG00000012976 ENSMAUG00000002731 ENSMAUG00000016481 ENSMAUG00000006987 ENSMAUG00000013284 ENSMAUG00000009211 GRM3 ENSMAUG00000017130 SH2D7 ENSMAUG00000015213 FNDC1 ENSMAUG00000000696 4933430I17RIK ENSMAUG00000003358 EPHA5 ENSMAUG00000003338 ALOX12E ENSMAUG00000017851 NEUROD2 PRELID3A ENSMAUG00000009140 ENSMAUG00000003389 ENSMAUG00000007272 FAM24B ENSMAUG00000010198 ENSMAUG00000001140 ENSMAUG00000015456 ENSMAUG00000002526 ENSMAUG00000005146 ENSMAUG00000009406 ENSMAUG00000000957 GM19426 ENSMAUG00000002852 ENSMAUG00000015730 MIR34B CUNH10ORF90 ENSMAUG00000003869 ENSMAUG00000004111 ENSMAUG00000018624 ENSMAUG00000019045 ENSMAUG00000001601 ENSMAUG00000008223 ENSMAUG00000002453 ENSMAUG00000007813 ENSMAUG00000014337 ENSMAUG00000017634 ENSMAUG00000002631 ENSMAUG00000009955 ENSMAUG00000021947 ENSMAUG00000017589 ENSMAUG00000009504 ZFP536 ENSMAUG00000005993 ENSMAUG00000021737 ENSMAUG00000016284 SEL1L2 ENSMAUG00000015289 OLFR464 ENSMAUG00000006564 ENSMAUG00000010484 ENSMAUG00000005890 SCD3 ENSMAUG00000010250 ENSMAUG00000001486 ENSMAUG00000020913 SNORD29 ENSMAUG00000020454 ENSMAUG00000005726 ENSMAUG00000006500 CACNA1I ENSMAUG00000016694 ENSMAUG00000009833 ENSMAUG00000007179 ENSMAUG00000012028 ENSMAUG00000008014 3-SEP ENSMAUG00000013965 ENSMAUG00000003376 ENSMAUG00000017113 ENSMAUG00000013841 ENSMAUG00000001606 ENSMAUG00000019447 ENSMAUG00000001258 IQCA1L NOL4 ZFP811 ENSMAUG00000007014 ENSMAUG00000005966 ENSMAUG00000017105 ENSMAUG00000019193 ENSMAUG00000021196 CLRN2 ENSMAUG00000004226 ENSMAUG00000001592 ENSMAUG00000004374 Top 500 down genes for SARS-CoV-2 infection in Mesocricetus auratus hamster lung Day 14 from GSE162208 Bulk RNA-sequencing was performed for lung of SARS-CoV-2-infected hamsters at 14 days post-infection. GNA11 ADAMTS1 STMN4 IL1B CHPF CXCL5 CKM YIF1A ANXA2 TUBA8 HSPB1 VIPR1 COQ8B CES2E GPX1 SERPINE1 UBA52 PTX3 RSPH6A ACADVL MGAT4B RAE1 TIMM10 PHB ISG15 ACADS PLP2 RFESD ZC3H12C POLRMT CPT1A DHRS1 RCAN3 TGFB2 RGS2 SCGB3A1 USF3 PEAK1 STEAP4 ANKRD33B ISG20 LCN2 TMEM246 TMEM109 TAGLN2 SEL1L AQP3 SIK2 LRRC25 GPD1 LMNA SLC16A3 EMP3 PPP1R12C HADHA ADAM15 MARVELD1 WFDC1 HADHB RRAS PRRT4 DUSP7 OLFML2A HP NKIRAS2 FAM160A1 LRFN3 CRIP2 CCN3 CXCR2 G0S2 IGFBP3 PHOSPHO1 IL18RAP GADD45B SERPINF1 AMTN ADAP1 MMP25 LTF CYB561 JAG2 LRP6 PRICKLE1 SOX7 SLC9A3R2 UPP1 PTH1R ZFAND3 PHC2 HSD11B1 IRF7 TCF19 CORO1A APOBEC1 BVES DHRS7C TNNT2 CASQ2 BPIFA1 MYH6 TNNI3 FABP3 MYBPHL MYBPC3 CSRP3 MB CKMT2 MYL4 APOL6 NTRK2 HMGCS2 GLIPR2 ARG1 UBE2L6 ANGPTL4 CDH22 EPHA1 UCP3 ACTC1 TMCC2 PSENEN GNAI2 COX6A2 TNNC1 MYOZ2 TMEM100 TMCC3 TPPP3 RAMP2 SMAD6 ANAPC13 GATA2 IRF9 TMEM204 CLEC14A SOX18 SEMA3C SPECC1L COX7A2 CRIP1 PLIN2 SLC16A11 SERPINE2 LYVE1 PSMB6 COX8A S100A6 BRK1 HADH EFNB1 ICAM2 IFI30 LAMTOR1 EVA1B PIM3 S100A16 KLHDC3 FAM107A TUBB2A TMEM259 CDO1 VTI1B TNNI2 KIF26A GUK1 RGS5 FXYD1 CD151 FPR2 NDUFB10 NDUFA7 PGLS MFHAS1 TSPAN18 GABRA1 PADI4 PGLYRP1 SPON2 GJA4 NPDC1 UNC5B IER5 BAMBI MRPL46 S100A11 SSSCA1 CCDC124 MANBAL NDUFA8 SCG5 PFKM RPS6KC1 LTC4S LRRC3 SRPK3 GAS2L1 B3GALT4 ORAI1 NEURL1B VEGFC TMEM115 SNX15 ABL2 MYLK2 S100A8 ANKFY1 TCAP HSCB RARRES2 TESC NPW SCGB1C1 MX2 PDPK1 UCP2 IGF1R SERPINA1 COPE R3HDM4 SERPINB1 LTB RAB29 ITGAD CHST2 CENPV CDC42EP2 SEMA7A CCDC184 ACTG2 NKAIN4 CXCL12 CD300LG NRXN2 TAL1 PGK1 CCL12 LIPE AGO2 TBX2 NR2C2 MOB3A EEF1A2 ACAA2 ORAI3 ABHD8 NUBP2 LIN37 ALDOC PEX10 NOXO1 LRP3 AKAP13 THOC6 METRN MBD3 PROK2 CYSTM1 HSPB6 SNAI1 NCAPH2 PCDH1 ERCC1 FXYD6 PRICKLE3 ZFYVE9 TRF HDAC4 CDK19 RALGAPA2 BACE2 PDGFB DYRK2 AKT2 EIF4EBP1 CPT1B CCL21 SMCR8 MTHFD1 GSTM3 GIMAP1 S1PR4 ACSM5 ALOX12 HSPB2 IL11RA ANAPC1 TIMM50 BYSL NOP53 HSPB7 PECAM1 TXNRD3 RNASEK MGST3 ETFDH AK1 JOSD2 SDHC TXNL4B TANC2 USP31 FEM1A PKDCC NTHL1 THAP11 N4BP3 PPP1R3C HYAL2 PDE3A DGCR6 ATRN PTPRK HIPK1 CCDC93 MACROD1 WDR18 NDUFS8 CARD19 ECH1 TIMM17B PFKP CAVIN3 ATPAF2 DOHH MED4 EIF6 GSTM6 OAF H2-T24 DGKA KIF1B REM1 FAM110D RASL12 ITIH5 DES CENPB ELOF1 AES LRRC28 NHLRC2 CD3EAP ATP2B4 SDHAF1 GPR180 LMOD2 TRABD ZNF775 FAM89B POLR2I FER PALM JADE1 PIEZO2 TOR2A EVI5L I830077J02RIK SH3D21 COG7 CECR2 EIF2B3 NSMCE2 CHN1 TTC9B KCNK3 CHST12 BORCS6 CALHM2 EVC LMO1 BBS9 PDZRN4 PDZRN4 PCBP4 FAM212A TEDC1 TSSK6 NXPH4 FIBIN CNTN2 CCDC102A CNIH2 OVOL3 ENSMAUG00000015164 ENSMAUG00000009739 ENSMAUG00000000936 CUNH11ORF68 ENSMAUG00000007782 ENSMAUG00000018493 ENSMAUG00000019177 SNORD110 ENSMAUG00000009219 ENSMAUG00000001480 ENSMAUG00000020394 ENSMAUG00000016015 ENSMAUG00000008734 ENSMAUG00000015635 MILL2 ENSMAUG00000016894 ENSMAUG00000002343 ENSMAUG00000014781 ENSMAUG00000006005 ENSMAUG00000019155 ENSMAUG00000008077 ENSMAUG00000017204 ENSMAUG00000008911 ENSMAUG00000007867 ENSMAUG00000019493 ENSMAUG00000021330 ENSMAUG00000007215 ENSMAUG00000009068 ENSMAUG00000005911 ENSMAUG00000001917 ENSMAUG00000018531 ENSMAUG00000000601 ENSMAUG00000008751 ENSMAUG00000008889 ENSMAUG00000017088 ENSMAUG00000012867 ENSMAUG00000014000 ENSMAUG00000014493 ENSMAUG00000000688 ENSMAUG00000009695 REG3GAMMA ENSMAUG00000007948 4-SEP ENSMAUG00000003456 ENSMAUG00000015724 ENSMAUG00000015088 ENSMAUG00000016756 ENSMAUG00000018177 NMRK2 ENSMAUG00000020594 C030006K11RIK ENSMAUG00000008691 ENSMAUG00000020834 ENSMAUG00000005989 MISP3 SLN MIR208B CUNH9ORF16 MIR208A ENSMAUG00000009903 ENSMAUG00000022058 ENSMAUG00000021832 GM24067 FMO6 ENSMAUG00000006470 ENSMAUG00000017254 ENSMAUG00000021876 ENSMAUG00000018054 PNPLA1 ENSMAUG00000011029 GM26602 ENSMAUG00000013343 ENSMAUG00000014101 ENSMAUG00000014857 ENSMAUG00000013593 ENSMAUG00000020479 ENSMAUG00000017563 ENSMAUG00000019971 ENSMAUG00000011668 ENSMAUG00000007327 GPIHBP1 ENSMAUG00000014727 ENSMAUG00000019133 ENSMAUG00000019852 ENSMAUG00000013723 SNURF ENSMAUG00000017644 ENSMAUG00000009896 ENSMAUG00000016448 ENSMAUG00000010057 ENSMAUG00000005476 ENSMAUG00000018508 ENSMAUG00000018377 ENSMAUG00000007417 ENSMAUG00000002860 ENSMAUG00000000680 ENSMAUG00000014278 ENSMAUG00000014635 MIR210 ENSMAUG00000002749 ENSMAUG00000004121 ENSMAUG00000006018 ENSMAUG00000016526 ENSMAUG00000020424 ENSMAUG00000011363 ENSMAUG00000002884 ENSMAUG00000016593 ENSMAUG00000014449 ENSMAUG00000013802 ENSMAUG00000005541 ENSMAUG00000005350 ENSMAUG00000015084 ENSMAUG00000009570 VEGFD ENSMAUG00000016140 ENSMAUG00000006745 GM13889 Top 500 up genes for SARS-CoV-2 early infection in human male blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 CEP250 MAPK3 CD14 FKBP1A PSMD8 SQSTM1 PRKACA PPP2R1A LMAN2 SLC9A3R1 PTCRA TMUB1 CCND3 IFITM3 YIF1A UBXN1 AATF PKM ANXA2 ST14 TUBB4B AP2M1 RAB8A CALM3 PSMD4 KIAA2013 TUBA1C CTSD NUCB1 TUBA4A RELA HLA-A IFITM2 CYB5R3 NDUFB9 PLD3 PEPD PES1 SIL1 TGFB1 YWHAH FERMT3 AGPAT2 FBP1 SPI1 CHMP2A PLP2 NEU1 BRI3 EXOSC4 MGAT1 SGTA DEDD2 ENO1 DCTN2 BAP1 NINJ1 IFI27 FTL ITPK1 CD2BP2 SMARCD2 BAX ARHGAP30 BANF1 LSP1 PTPA NACC1 STMN1 RIC8A DDX41 UQCRC1 SLC3A2 PGD HS1BP3 VASP XAB2 PNPLA6 SRPRA SF3B4 SNRPB DDRGK1 TBC1D10B SRSF9 CORO1B DOK2 BST2 SDF4 PLOD1 PLEKHO2 MAP3K11 NDST1 KCNAB2 SMARCD1 EMP3 ARHGDIA GRN TOLLIP SYNGR2 ZYX SCAMP2 CCT5 TIMP1 MYBL2 TWF2 C1ORF162 CAPG CCNB2 TUBG1 CTSB RAB20 E2F2 CDK5 KIAA0930 NDUFS7 AP2S1 RENBP MZB1 NDUFAF3 CAPNS1 RRM2 PAQR4 CTSZ CES1 KIFC1 MPND HSD17B10 MYDGF GAPDH CLTA HDLBP ATP5F1B ABCD1 TPX2 PKMYT1 PSMB2 TPI1 TBC1D2 CDKN1A CAPN1 CLU TFIP11 FIBP CD63 PREB RNF26 TRIOBP CCDC9 ZNF628 SCAMP4 OGFR EPN1 ARMC7 SASH3 PYCARD DEF6 ARHGDIB RAC2 COTL1 FCER1G CHAF1A OSCAR CPNE5 GLIPR2 DAXX PSME1 FTH1 RPL28 GNAI2 PFN1 SHISA5 LY6E TUBA1B PSMB10 CHMP4B HPCAL1 RHOG CAPZB GSTP1 EGFL7 NDUFA3 CLDN5 P4HB S100A4 BCAP31 CST3 MDH2 PPIB EIF5A PPP1CA PSMD3 NDUFS6 SH3BGRL3 NDUFB11 KDELR1 HCFC1R1 VIM ESAM PEX6 LYPLA2 ADRM1 CALR MRPL28 FXYD5 CFL1 ARF1 JDP2 EHD1 ALOX5AP EDF1 S100A10 CD151 NDUFB10 SCAND1 CCDC85B PGLS TOR4A SERTAD1 UBE2L3 UBE2S ALAS1 PDLIM1 UBE2M CIDEB WBP2 S100A11 RBM42 GPKOW MIF SRM PGAM1 RNASEH2A NRBP1 ATP6V0D1 SLC25A11 SF3A2 PSMB3 TFPT CCDC124 ORMDL2 PPP1R7 VPS72 PPP1R18 MFSD5 MGLL NELFE SLC10A3 SPCS1 CCT7 RUVBL1 CUEDC2 RAB1B SDF2L1 RUVBL2 NUDC SURF2 IK PGM1 HDGF GAS2L1 CSRP1 EMD TMEM115 CTDP1 B3GNT8 MUL1 C6ORF47 PIGT STYXL1 CSK SMOX SNX20 GP9 BTBD2 LENG1 MAP1S DCPS RFC2 BOP1 KLHDC7B VAT1 ARPC1B COPG1 CSTB ALDOA CTSA CNPY3 COPE NRGN GPSM3 PTPN6 ILK HMGN2 CDA KLHDC8B OSGIN1 TMEM214 GFI1B PSMC4 NUBP1 PEF1 SDHA STX5 PSMD7 TRAPPC1 TADA3 RAB35 RNF113A SEC13 UBL4A ACTR1A FUT7 APOBR TNIP1 RIN3 TFEB CLPP TNFRSF1B GNAS ERP29 GBA SPRYD3 TOM1 PPP4C FKBP2 NR1H2 AIP BAK1 UBALD2 PSMC5 MAPKAPK2 PHGDH PSMC3 FADD TRIM11 SLC35A4 SZRD1 CREB3 CCDC92 CHMP1A ALDH3B1 MPST ABHD8 SMARCB1 IRF2BP1 RALY CLTB DDA1 VPS18 HDAC5 LRP3 TTLL12 RNPEPL1 PTPN18 RNF185 KATNB1 PPDPF PARVB CYC1 SLC38A5 DAPK3 SLC39A7 PLEKHM2 KAT5 VPS37B TSSC4 PSMD2 FDPS MAF1 FXYD6 XRCC6 PRICKLE3 APEX2 UNC45A FDFT1 GPATCH3 PLIN3 WDR1 USF2 KEAP1 SIRT6 PIAS4 HSF1 ATG101 ATG13 LRRC59 DAP CPTP SNAI3 CD300LB ALOX12 LIMK1 VPS4A BRMS1 PDAP1 PPM1G BABAM2 THAP4 PRCC POLDIP2 HNRNPAB MRPS34 SNRPC ZNF282 NFKBIB MAP2K2 ECHS1 PNKD TMEM219 JOSD2 DYNLRB1 POLR2L MAGED2 PMVK NRM GNA15 ZNF672 RNF40 POP7 ZNF787 RTL8C PPP1R11 ZMAT5 JPT1 ECH1 YIF1B PAFAH1B3 RFXANK FARSA SLC35F6 CCDC71 RBM10 C11ORF68 CCDC69 HIRIP3 H2BC12 KIF1C EIF6 SPCS2 ILRUN PKN1 SF3B2 MICALL1 MRPS18A HDGFL2 AGPAT1 SH2B2 CENPB TAF6 SNRNP35 BLOC1S3 NAT8B MED8 OCEL1 RUFY1 ZNF213 EIF4A3 GTF2F1 DOK1 SH3BP5L SUGP1 TACO1 CCDC97 SART1 CHMP6 DCTN1 SH3GL1 PUF60 PAF1 EXOC7 CTDNEP1 CCDC12 ACRBP TOR2A RPP25L GET3 GARS1 BORCS6 DMAC2 NELFB TMEM250 OPRL1 H2AX MTG2 VRK3 CMTM5 NAA60 PCIF1 ZNRD2 YARS1 SLX9 FAM174C SGF29 H1-10 YJU2 SLC66A2 MMP24OS RTF2 SEPTIN5 SARS1 Top 500 down genes for SARS-CoV-2 early infection in human male blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 PPIL3 RPS27A CEP112 EEF1A1 CEP350 BIRC3 GCC2 WASHC4 DDX5 MACF1 PLEKHF2 BRAF ATM PSMC6 BIRC2 MYCBP2 ITGA4 ELK4 AKAP9 PPIG SBNO1 USP15 LNPEP CASP3 SLC30A6 CHD1 FBXO3 MYNN DMXL1 PCMTD2 NR3C1 USP34 RBM39 TMEM30A ABHD3 CACNB4 POLI RPS6KA5 N4BP2L2 NAE1 PFDN5 POLR2B RPS17 SH3D19 RPL21 RPL35A RPL9 POU5F2 ZEB2 RPL27 RPS15A RPS24 TPT1 NFAT5 ZNF91 RALGPS2 USF3 RPS3A RICTOR RPL30 RPL23 FAM214A TET2 UTRN RPL39 BDP1 RPS18 RPS29 RPL31 RPL11 TC2N RPS7 RPL7 RPS27 TTC14 SEL1L TM9SF3 MTERF2 KLRB1 TOPORS MGAT4A HINT1 ZNF195 ABCC5 ABCD3 B4GALT6 CYP4V2 ABCE1 MAPK8 MED23 SRSF1 DDHD1 HNRNPH1 PNN SH2D1A EVI2A UQCRB TMA7 PPP1CB RPL5 EIF3E EEF1B2 LUC7L3 RPL26 RPS21 ZNF780A NR1D2 RAP1B HIPK3 RHOQ DDX3X MBNL1 SP3 PCNP TOMM20 NDUFA5 CCNL1 CAPZA2 EIF4A2 POLR2K CETN3 DDX39B ATP2B1 DYNC1LI2 RPS27L SLC38A2 BNIP3L DEK CBX3 CLEC2B LRRK2 ZNF267 ZNF292 GIMAP2 FEM1B TAF1D BTAF1 ZBTB34 TMEM243 HMGB1 PAN3 NOP58 GNAI1 RPS6KA3 PDCD10 USP1 PAPOLA UBA3 RPL34 RB1CC1 ATP2C1 GPBP1 RSRP1 OGT ARGLU1 SRSF2 NUFIP2 SRSF7 TBL1XR1 CEP192 CD46 CD47 PIKFYVE GOLGA8B PRPF39 FNBP4 TMEM126B RECQL MAN2A1 LPGAT1 ARID4A SMG1 TIA1 XRN1 STX16 METTL4 ANKRD49 ZRANB2 PRRC2C NIPBL BBX CCDC186 PIK3R1 TNRC6B ATRX ASH1L ANKRD12 HERC1 BOD1L1 PNISR THOC2 RSF1 AFF4 SMCHD1 FMR1 SF3B1 XPO1 SRSF11 COX6C AKAP11 ROCK1 SON MS4A1 PUM2 RCOR3 ZNF404 PDE7A PPTC7 FRY CLK1 CDC14A DHX36 VPS29 ZNF655 VPS36 PEX2 PFDN4 SACM1L RANBP2 TANK IDI1 THAP12 USP33 CREB1 DPP8 MDM4 DICER1 FAM111A RNF11 STX7 TMEM167A TSNAX TBRG1 COX20 ATG12 CYLD CMPK1 AHNAK CGGBP1 BLOC1S2 CIAO2A COMMD6 CARD8 PHC3 ATP7A DIP2A EML4 KTN1 NEMF REV1 VEZT GPCPD1 BBIP1 NFYB U2SURP GNL3 USP16 WDR75 CCAR1 HERC4 GOLGA4 ZMYM2 SYNE1 UNKL SYNE2 RGS18 TAF1 SUN1 PPP1R12A SREK1 ZNF451 KAT2B PBRM1 PDE3B SLC7A6 ZBED5 TRPM7 NUP160 USP9X KDM3A NCOA2 KMT2A KMT2C ZBTB18 JMJD1C SMC4 TRA2A IL6ST PRKAA1 ORMDL1 ATG2B ERBIN SENP6 FBXW7 UBR5 MFN1 PRKDC SESN3 VCPIP1 RSBN1L ZMYM6 RBAK ZNF224 ZNF26 SNX13 CLEC2D ABCA5 UBXN4 SHOC2 TRIP11 ZDHHC17 RABEP1 FBXO11 ANGPT1 SLC23A2 MAP3K2 NAA15 CCDC88A BCLAF1 RRM2B BIRC6 TACC1 PPWD1 ANAPC4 ZNF24 TXNDC9 OGFRL1 COX7B HECA TOMM7 USP24 LYST MGA ITSN2 MED13L ZFX ZNF140 CLK4 HIVEP1 MYSM1 MAN1A2 RNPC3 PTAR1 SLK DCUN1D1 UBN2 PHIP DOCK11 RSL24D1 CLDND1 AGTPBP1 ZC3H6 C9ORF72 BTF3L4 LGR4 PHF20L1 TBC1D4 DMXL2 PAXBP1 ASXL2 MED13 MRFAP1L1 TRAPPC8 ZBTB1 CREBZF MAP4K5 PPP4R3A CDC42SE2 WAPL C1ORF52 ANKRD10 CNST MON2 BAZ2B PCF11 SUGP2 GOPC TUT4 MICU3 BRWD1 PRKAB2 NAA16 H1-3 H4C3 ARID4B FRYL DENND4A ZC3H13 ZNF85 ERGIC2 ECHDC1 KIF5B RBM25 FGFR1OP2 EIF5 PRPF4B ZFC3H1 ZNF281 ZNF776 CEP95 KIAA2026 EPM2AIP1 INO80D RELL1 VPS13C SMC6 ANGEL2 CCDC146 DNAJC10 EFR3A PPIP5K2 OPA1 UVSSA RABGGTB ITPR2 BPTF GSAP NKTR PDS5A BRWD3 CFAP36 KIAA1109 CEP295 CNOT6L RAD50 LSM8 FYTTD1 EIF1AX SLMAP RORA AFF1 EXOC5 MAP9 PNPLA8 FAR1 PGGT1B MOB1B SPOPL OSBPL8 CEP57 HAUS3 SNX14 AP1S2 COPS2 UBE3A KATNBL1 TMEM161B ATL2 NR2C1 HEATR5B KLHL9 ZNF638 TARBP1 FAM204A ODF2L PKN2 SRSF10 SCGB2B2 AGO3 ZNF33A CRBN AMY2B PCGF3 TRIM33 INTS6L RIF1 C2ORF49 ZNF493 ARL14EP CSAD PPP4R3B ALG13 ANKRD44 USP12 N4BP2L1 EDRF1 KRR1 CCDC66 SCLT1 TASOR RELCH TTC13 ZBTB37 PHF20 NSUN6 ZNF83 ZNF708 MINDY2 GOLM2 BPNT2 GPATCH11 TAS2R20 DYNLT2 RBIS ODR4 NKAPD1 CERT1 MARCHF6 KLRC4 ABRAXAS1 Top 500 up genes for SARS-CoV-2 early infection in human female blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 DCAKD CEP250 UHRF1 HSPA5 HYOU1 PDCD1 CHPF CAPN2 TRIB3 TOM1L2 GCC1 CCND3 RASA3 NDRG1 FBLN5 LAP3 GGT1 SRP54 SIGMAR1 OAS1 DNMT1 SELENOS TUBA1C ACE ERBB2 RETSAT APOBEC3G OASL WFS1 PXN CRTC3 MOV10 TTC38 TBKBP1 CCDC86 THOP1 GORASP1 NUB1 EVL PLEC CDK2 MYD88 NEU1 LRRC8A SBK1 FGFR4 MYO6 CPT1A ALDH8A1 NT5DC2 IFI27 MXRA7 MT1E EVA1C OTUD7B RGL1 ADGRG1 SLC25A23 TTC22 ATP10A TMEM184B CMTR1 ANKRD52 CYBC1 PDIA6 GLYR1 RMDN3 STMN1 SLC3A2 HS1BP3 ZC3H7B TUBGCP6 PCNX3 PDIA4 SLC38A10 PLK1 GLMP MYBL2 TOP2A CCNA2 TK1 NAIP CCNB2 TUBG1 GTSE1 AURKB CDCA5 OTOF MCM2 CDC25A MZB1 DLGAP5 BUB1 RRM2 E2F1 KIF4A EPSTI1 MYDGF EPHB2 TPX2 CCNB1 NCAPH CDC20 PKMYT1 HJURP SPATS2L MKI67 ARNTL2 GNPDA1 TYMS CD247 LRFN3 SH2D1B ARL4C LGR6 FGFRL1 SH2D2A G0S2 RUNX3 TSPOAP1 PRDM8 YPEL1 COLGALT2 RAB11FIP5 CACNA2D2 LLGL2 TUFT1 GADD45B ZNF707 CISH B3GNT9 PGAP2 SNPH FOXM1 ZBTB42 JUP FAM83G SLC7A5 ITPR3 SLC7A1 BNC2 SLC4A2 RSPO4 AXIN1 DVL2 CTRC RGS3 TRIOBP FOSL2 SLC16A5 RAB11FIP3 CYHR1 HELZ2 C10ORF105 ZNF646 SBNO2 MIDN SGSH SASH3 IL10RA CCNA1 LAX1 FANCI ZBP1 TCF19 RAD51 SLAMF7 CKAP2L SPC24 IL2RB NUSAP1 CX3CR1 RACGAP1 SPC25 MELK TKTL1 CCNF TBX21 LAG3 PTPN7 CDH26 OAS2 PHF19 CHAF1A USP18 NKPD1 HERC6 GNAL SOCS3 SHISA5 LY6E JUN ITM2C PIM3 CALR MYO18A KIFC3 PI16 TRAF1 DGKQ QRICH2 PTGER2 CCND2 CLSTN3 FBXL16 TMEM120B DUSP5 CSRNP1 PTTG1 PCNA PIGP DDB2 SDF2L1 CDC25B MFAP1 PARD6A SORCS3 TPST2 FANCG DHRS13 CTDP1 ADAMTS14 TNNT1 NCR1 PRF1 FEN1 POLR3H TNNT3 DNASE2 TRIM14 CCRL2 IKZF3 SNX20 ELOVL6 TMEM229B SLAMF6 C19ORF25 SLC1A4 CD38 CPA5 ATP1A3 SFXN3 PAQR6 GSDMB APOBEC3B LIG1 TMEM140 PILRB PEBP4 ACOT7 TPRA1 PIP4K2C ST6GALNAC6 KLHDC7B SIDT1 BTN3A3 DUSP4 BTN3A1 JADE2 TRIM26 GALM ENO2 HMGN2 FOLR3 GZMB LYG1 KLHDC8B ITPRIPL1 HEYL ACTA2 RALGDS SSTR3 LSMEM2 CD70 CERCAM TP73 RUBCN ALG1 FTSJ1 USB1 TXLNA APOBEC3F CD300A IGF1 DPP9 XBP1 TXNDC5 LARS2 BAK1 GPN2 TMX2 ARF4 TSPAN14 ANKRD11 XYLT2 SUV39H2 HIRA SLC35C1 ECHDC2 HMGXB3 JRK KCNC4 TRIP6 PLEKHM1 SLC39A13 FBXL8 LSS FDXR MROH8 PIM2 CCDC71L FOXK2 RXRB KCTD10 CTPS1 NISCH EDC3 GAS6 LZTR1 TXNDC11 PCDH1 PRICKLE3 TCTN3 PRSS27 TMCO4 SREBF2 CLPTM1L KEAP1 SRF CDKN2A BHLHA15 KRT72 CBX7 SPRED2 ABCA3 LRRC59 PRR5L FPR3 SLC26A11 TRPC6 DNM2 ZNF133 ABCA2 TRIM35 GTPBP1 ABCB8 ICMT EDA SLC2A14 EYA3 GPSM1 DFFB DHX37 GRWD1 MLLT1 SLC35B1 ZNF142 SLC25A20 HDHD3 RFT1 BMP8B SRPRB RAD51D ARID3B AEN ZNF319 ZNF526 KDM5C ZSWIM4 APOBEC3D KIF21B SYTL3 CAPS GALNT10 GMPPB PIF1 ANKRD54 STOML1 NMRK1 CNP C1QTNF6 GTF3C1 MYRF AARS2 RNF43 SZT2 TMED1 PRR7 C2CD3 PFKP CCDC71 C11ORF24 ZSCAN20 CAPN15 CBX6 H2BC5 H2BC12 H1-0 ST3GAL2 TM9SF4 KYAT1 GIMAP6 CCDC88C DDX23 SBF1 AP2B1 PTPRN2 FAN1 MLLT6 USP35 COPS7B DAB2 GPR153 DENND2D PROSER1 STX1A APBB3 CACNB3 ZNF213 SMG5 COPS7A PRKCQ SH3BP5L TLNRD1 PGS1 ASPHD2 PHACTR1 COLQ ZC4H2 CCDC97 SNAPC4 MR1 EXOC7 ADCY3 ZNF251 C3ORF18 LIME1 RNF157 GNAO1 SLX4 TMEM191C IFT27 MRPL53 LRRC41 CCNK STK35 EDARADD DDX31 BET1L KCNAB3 FBXO46 P2RY11 L3MBTL2 MYH3 CHST12 SLC35F2 SCN8A NPTXR SCMH1 BAHD1 KCTD14 EVC EPOP TMEM25 ADAMTSL5 CNNM4 MLC1 PRR29 WDR76 IQCN OPRL1 PAAF1 H2AX SPINDOC APOBEC3H TTC12 KCTD21 PYHIN1 NMUR1 HOMEZ TIGIT DOCK3 CHRNE VWA7 CARMIL3 CACNA1I YARS1 FBH1 FHIP2B ZNF691 GPR25 PPIAL4C EOLA2 B3GALT9 KRT73 EZHIP CPLANE2 RUSF1 MEAK7 VPS37D Top 500 down genes for SARS-CoV-2 early infection in human female blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 UBB SPTB PPIL3 RPS27A PPBP EEF1A1 TBCA FGL2 IGSF23 ATP5MG UBXN6 ASAP2 SLC7A7 SMIM24 RALA NGDN ARHGEF4 RBX1 SCCPDH FCER2 FAR2 RAB18 HBQ1 PSMC6 ABCG2 FAU HSBP1 PMPCB PPIG GHRL FKBP1B DPH5 TMEM253 FBXO9 NAP1L1 LIPT1 SLC25A39 AGBL3 PKIG TMLHE CHPT1 VLDLR WDR89 MPP7 KMO ASB9 CAMLG BCL2A1 ATP6V1G1 RPS20 BTF3 PFDN5 RPS17 RPL21 RPL35A RPL9 IL5RA RPS12 RPS11 RPL27 PARD6B RPL41 RPS15A RPS24 TPT1 SH3BGRL2 RPL6 RPL37 RPS8 RALGPS2 RPS3A CD180 TP63 GALNT5 RPL30 RPL23 RPL13A RPL24 RPS25 RPSA CYBRD1 ADAM28 RPL39 RPS13 RPS18 BBOF1 COX7C RPS29 AIF1 RPL31 RPL11 RPS14 RPS7 RPL7 RPS27 RPL27A TGFBI SPATA20 CPVL CLTCL1 HVCN1 SEC11A ALCAM ARPIN OPN3 CBWD1 NDUFS4 ROGDI LTA4H LGALS3 RPL26L1 ECHDC3 SOWAHD GPER1 CDC42BPA ATP5F1C CROCC2 KLRB1 CLC HINT1 SERHL2 IGBP1 ABCD3 RAB4A SFRP2 NUCB2 TMEM164 CYSLTR2 KLRC1 MS4A6A LY86 GLIPR1 MYOM2 TXLNB ALOX15 MYL4 IFIT1B CD86 ALAS2 HBB TRIM10 SLC4A1 SNCA CD19 SNX22 IGFBP6 CSTA TNNC2 RBP7 SLC35F3 KLF4 UQCRB TNS1 YBX1 TMA7 YBX3 BAG1 ADIPOR1 PLVAP TPPP3 RPS23 COX7A2L RPL3 RPLP0 RPL5 EIF3E CCT2 EEF1B2 RPL26 RPS5 RPS21 GDI2 RPL4 ARPC3 NDUFB3 RPL35 SRP14 RPL15 TOMM20 NDUFA5 EMC3 AQP1 CAPZA2 NAB1 ANXA1 SELENBP1 GNG11 NDUFA4 POLR2K NRP1 MYLPF VBP1 GUK1 GLRX5 DBI MRPS18C BNIP3L CBX3 PIK3R6 LST1 SLC5A5 LGI4 ERMAP LYPD2 NAPSA PROC DMTN LGALS2 YOD1 FOXO3 DEPDC7 SNRPG PDZK1IP1 HAT1 PSMA4 ASNSD1 TXNDC17 SLC29A1 HMGB1 UQCRQ GSKIP MRPS23 GNAI1 SYPL1 PDCD10 VAMP7 SNX4 MRPL32 SNRPE RPL29 TAX1BP3 RPL34 MXI1 GFM2 MKRN1 PPM1H CNFN ZNF32 PCDH9 PRRT2 MKKS SLIRP P2RY14 SPATA7 S100A8 PCGF5 TNFRSF13C BTLA BCL11A SPNS3 CTSE RGS10 HLA-DMB TESC DDX43 SEC14L5 C3ORF33 TMEM126B GYPC ORM1 MBNL3 KBTBD7 SEC62 CD302 CDCA7L SLC35A1 RPL22L1 FBXO33 ZNF713 MAP10 SLC28A3 HLA-DRA FAM210B OPTN ALDH2 FBXO7 BLVRB MAP3K7CL CD52 RPS6 COX6C CALM2 LPAR6 ADAMTS5 LMOD1 KHDRBS2 SERPINB8 GRPEL2 ITLN1 RTN4RL2 IGF2 HBA2 FCRL2 KIF5A TAL1 CA1 CORIN ZDHHC1 GATA1 PHF5A VPS29 OLA1 ANAPC10 SEM1 SLC31A1 RIOK3 CARD16 HBA1 MRAS GNAQ FAAH RNF11 NEDD4 MFSD2B PAX5 TAF9 HAGH FUNDC2 TMEM183A CALHM6 PPM1A ATG3 ATP5F1E BLOC1S2 CIAO2A CLNS1A COMMD3 COMMD6 RPGR DCAF13 TSPAN5 NFYB GNL3 DPM1 CBWD2 HSPB11 POLE4 GAPT SPRED1 FAM214B METTL21A GSPT1 SNX2 PTK7 ACSM3 CPM ATP1A4 CMBL JAZF1 FXR1 IFT57 TMEM168 ZNF578 CD1D ATG10 ATG4C BANK1 STKLD1 CD1C SESN3 ZMYM6 MTHFS CLEC9A ABCB4 FLVCR1 SEC14L4 RFX3 SIAH2 BIRC7 SDHAF3 CRTAP TXNDC9 TMOD1 COX7B HIBADH STMP1 HNMT TPGS2 MFSD1 EIF3H TOMM7 TBC1D22B NFXL1 PDZD2 SLC25A37 NRCAM MPV17L MICAL2 NFIX ZBTB7C DCUN1D1 CNTNAP3 RSL24D1 IGF2BP2 SLC9A7 ZNF277 BTF3L4 ZNF703 DLG1 SNRPD1 NSA2 TBC1D32 FRA10AC1 LSM3 TMCO1 DENND4A NUDT3 ECHDC1 PRG4 ZNF770 UBXN11 CLEC10A DCAF12 THAP5 TMEM132E FRMD4A KCNMB1 MTURN TSPAN2 RABGGTB BORCS7 RFX2 FAXDC2 CFAP36 FAM174A GPR146 APOLD1 GYPA SPECC1 HEMGN EPB42 NUDT4 STRADB LYRM7 MOB1B ZDHHC2 HECTD2 AP1S2 RNF144B CCDC59 LSM1 CRYBG3 SYCE1L FAM204A ZBED3 VENTX ZNF480 HELQ CECR2 SS18L2 TTC24 NSMCE2 TRIM33 ZNF814 ARL14EP P3H2 ADARB2 AJAP1 DNAJC28 USP12 AFF3 ERVH48-1 ADGRD1 CUTC POLR1D SAYSD1 NEURL1 DAAM2 NEK11 FAM221A DPY19L2 WDFY2 TRIM58 RTN1 DYRK3 CD248 SLFN14 PAGE2B C16ORF96 SMKR1 GRIN3B PPP1R3G TATDN1 PTTG2 EMID1 MTIF3 KCNE5 SHLD3 VSTM1 GPATCH11 PHF24 HTR3A SMIM27 MIX23 DHX57 ATP5MJ OR2W3 SHISA7 ODAD4 MARCHF8 Top 500 up genes for SARS-CoV-2 middle-stage infection in human male blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 DCTPP1 CES2 MAPK3 FKBP1A PSMD8 CTDSP1 SQSTM1 FBXW5 PRKACA PPP2R1A MAP7D1 LMAN2 SLC9A3R1 TSPO PTCRA RHOA UBXN1 TPM3 PF4 AATF PKM HLA-B TUBB4B KCNQ1 HSPB1 GRPEL1 SIGMAR1 AP2M1 RAB8A ANXA11 UBTD1 GPX1 CALM3 PSMD4 KIAA2013 EIF4E2 TUBA1C NUCB1 TST RAD23A TUBA4A NUTF2 HLA-A CYB5R3 MGAT4B NDUFB9 PES1 TGFB1 YWHAH FERMT3 MOB2 AGPAT2 CHMP2A MTMR14 EXOSC4 SCYL1 MGAT1 SGTA DEDD2 ENO1 DCTN2 BAP1 NINJ1 FTL TAGLN2 ITPK1 CD2BP2 BAX PNPLA2 ARHGAP30 BANF1 LSP1 PTPA NACC1 RIC8A GSK3A DDX41 UQCRC1 HS1BP3 CHID1 VASP RPS6KA1 PNPLA6 FKBP8 SNRPB GNB2 DDRGK1 TBC1D10B RETREG2 ITGB5 LMNA SDF4 PLOD1 URM1 MAP3K11 APH1A TKT EMP3 ARHGDIA TOLLIP WDR13 RHBDD2 SYNGR2 TIMP1 MRPL37 TWF2 C1ORF162 INKA1 HADHA KIAA0930 AP2S1 ATP6V1F FH NDUFAF3 CAPNS1 CTSZ MPND HSD17B10 GAPDH CLTA HDLBP ATP5F1B PSMB2 TPI1 KLF16 PHOSPHO1 CDKN1A BAD AQP10 ACTB HMGA1 IMPA2 CAPN1 CLU TFIP11 CTNNBIP1 MAP2K3 TRIOBP STK40 CCDC9 ZNF865 WDTC1 RXRA AKT1S1 EPN1 HCLS1 ARMC7 SASH3 SELPLG ASF1B PYCARD DEF6 ARHGDIB RAC2 CORO1A CCNF COTL1 CPNE5 DAXX PSME1 FTH1 RPL28 GNAI2 PFN1 TUBA1B ACTG1 CHMP4B HPCAL1 RHOG CAPZB EGFL7 CLDN5 P4HB S100A4 BCAP31 SNX17 MDH2 PPIB RPN1 GABARAP PRDX5 EIF5A PPP1CA SH3BGRL3 JUND NDUFB11 KDELR1 VIM OAZ1 ESAM LYPLA2 ADRM1 LAMTOR1 TALDO1 KLHDC3 MRPL28 FXYD5 CFL1 ARF1 LAPTM5 CDIPT EHD1 ALOX5AP EDF1 ELOVL1 EFHD2 TPRG1L MARCKSL1 S100A10 NDUFB10 SCAND1 GPX4 PGLS SAMD14 UBE2L3 PDLIM1 UBE2M WBP2 S100A11 RBM42 PGAM1 ATP6V0D1 SLC25A11 PSMB3 TFPT TTC1 AHCY CCDC124 PPP1R7 PPP1R18 PSMC1 YIPF3 POLR2E MGLL NELFE SLC10A3 CCT7 RUVBL1 DYNLL2 TUFM CUEDC2 RAB1B CHTF8 RUVBL2 NUDC IK MEA1 HDGF GAS2L1 B3GALT4 CSRP1 SNAPC2 EMD TMEM115 CTDP1 B3GNT8 MUL1 C6ORF47 CSK SMOX TREML1 SSNA1 TSPAN33 GP9 NFE2 PTMS BTBD2 RAB11B DCPS ALYREF METRNL RFC2 MLF2 VAT1 ARPC1B ANP32B CSTB ALDOA CNPY3 COPE NDUFB4 NRGN GPSM3 EIF1 MYL9 PTPN6 R3HDM4 ILK HMGN2 CDA GFI1B PRDX2 IRAK1 NUBP1 PEF1 STX5 PSMD7 TRAPPC1 TADA3 RAB35 RNF113A SEC13 SURF4 UBL4A ACTR1A SSU72 LYL1 RNF5 FUT7 TNIP1 RIN3 OSTF1 TRADD ARF5 BSG WIPI2 TFEB TNFRSF1B GNAS HMOX2 ANXA7 PPP4C FKBP2 NR1H2 UBALD2 ARAF PSMC5 GID8 HM13 FADD SLC35A4 SZRD1 CREB3 CCDC92 CHMP1A AURKAIP1 CLPTM1 CD99 ALDH3B1 ALKBH5 MPST ABHD8 SMARCB1 PINK1 ZNF524 ADI1 RALY CLTB HDAC5 LRP3 MAZ ZNF219 RNPEPL1 PTPN18 G6PD PPDPF PARVB SLC38A5 DAPK3 INPP5K KAT5 VPS37B TSSC4 CTTN PSMD2 FDPS GUCD1 MAF1 XRCC6 FDFT1 UBE2Q1 WDR1 USF2 LRPAP1 KEAP1 PTP4A3 VSIR AKT2 MCOLN1 PHF23 ATG101 ATG13 LRRC59 DAP FOXP3 CPTP SNAI3 PSMF1 ALOX12 CRAT PPP1R9B BRMS1 PDAP1 PPM1G PRCC POLDIP2 LSM4 RPUSD1 SHMT2 MRPS34 ZNF282 GRK6 PRDX6 NFKBIB MAP2K2 RHOC MSRA SLC48A1 ECHS1 TEX264 CYB5R1 CTDSPL DYNLRB1 POLR2L MAGED2 PMVK NRM SLC25A1 CARHSP1 RNF122 GNA15 SLC39A3 ZBTB45 RNF40 POP7 ZNF787 GPATCH4 DNAJC4 PRR7 MOSPD3 LHPP PPP1R11 UBL7 JPT1 ECH1 APEH YIF1B CCDC71 C11ORF68 DOHH CCDC69 HIRIP3 CD99L2 EIF6 DBNL ILRUN PKN1 ATP5F1D ST6GALNAC4 AGPAT1 UBALD1 CENPB SNRNP35 NABP2 ZNF622 DNAJB12 TANGO2 EIF2B2 ZNF213 EIF4A3 GTF2F1 TIMM22 DOK1 GAR1 TSC22D4 TRAF7 SART1 CHMP6 TSR3 SH3GL1 PAF1 CTDNEP1 CCDC12 ACRBP RNF208 EVI5L ZNF768 GET3 BORCS6 NT5M CERS4 NELFB TMEM250 R3HCC1 H2AX VRK3 CMTM5 NAA60 PCIF1 ZDHHC3 H2AJ MMP24OS RTF2 SEPTIN5 SARS1 KCTD2 MARCHF2 NAIF1 FNDC10 MPIG6B Top 500 down genes for SARS-CoV-2 middle-stage infection in human male blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 PPIL3 CEP350 BIRC3 GCC2 CNTRL HECTD1 MDN1 WASHC4 PTBP2 DDX5 MACF1 EP300 DDI2 SLC30A9 SEPSECS JAK2 TTN UHRF2 ATM PSMC6 BIRC2 MYCBP2 RBM41 ITGA4 ELK4 AKAP9 SBNO1 EDEM3 USP15 LNPEP CHD1 FBXO3 USP34 VPS13B RBM39 TMEM30A SLC25A16 ZKSCAN1 RPS6KA5 N4BP2L2 PFDN5 RPS17 SH3D19 RPL35A RPL9 SLC15A2 RPL27 RPS15A RPS24 TPT1 NFAT5 USF3 RPS3A RICTOR RPL23 FAM214A TET2 UTRN RPL39 BDP1 RPL31 RPL11 RPS7 RPL7 TTC14 GLRX ALCAM MGAT4A MYBL1 ATR ZNF195 EP400 MAPK8 MED23 SRSF1 ZNF217 DDHD1 STIM2 HNRNPH1 PNN SORL1 GPR65 MIS18BP1 NLRC5 SH2D1A MS4A7 PTPRC APOL6 GBP4 EVI2A CCDC18 GCH1 RNF213 MITD1 SP110 TMA7 IRF9 EEF1B2 LUC7L3 RPL26 TRAPPC6B HIPK3 DDX3X ZMYND11 MBNL1 NDUFA5 CCNL1 EIF4A2 CCNL2 ATP2B1 DYNC1LI2 RPS27L SLC38A2 DEK TAF11 CLEC2B LRRK2 ZNF292 GIMAP2 FEM1B TAF1D BTAF1 CHMP5 SRP9 PAN3 SMARCA5 ATG5 PDCD10 HMGN3 RPL34 GPBP1 RSRP1 OGT ARGLU1 KRCC1 NUFIP2 SRSF7 CREBRF HIVEP2 SRSF6 CEP192 CD46 UHMK1 CD47 REL TAP2 SLFN5 USP25 ZC3HAV1 DCP2 ANKFY1 PIKFYVE GOLGA8B PRPF39 FNBP4 LY96 GOLGA8A PIGL TMEM126B RECQL SLC20A1 FAM13B ZNF431 ARID4A SMG1 TIA1 XRN1 STX16 ZNF302 ANKRD49 DDX60L ZRANB2 UFM1 CCNT1 PRRC2C NIPBL BBX CCDC186 ZBED6 TNRC6B TMEM181 SMC5 SMURF2 ATRX ASH1L SIKE1 PRKACB ANKRD12 CEP290 HERC1 BOD1L1 PNISR THOC2 RSF1 ESCO1 AFF4 CPEB2 SMCHD1 FMR1 COG3 SF3B1 XPO1 SRSF11 COX6C ROCK1 KLRK1 SON PUM2 DYRK1A ATF7IP FRY CLK1 PUM1 DHX36 PHF5A VPS29 ZNF655 VPS36 PFDN4 SACM1L TENT5A RANBP2 IDI1 THAP12 MTR DICER1 TNKS CDK6 FAM111A STARD3NL IFT20 ATG12 CYLD UBA6 CMPK1 AHNAK BLOC1S2 C6ORF62 CLNS1A COMMD6 POLR3G ZC3H11A MTRF1 DNAJB14 CARD8 PHC3 HELZ DIP2A KTN1 NEMF REV1 VEZT RBBP6 ZNF430 CEBPZ USP16 WDR75 CCAR1 CCNT2 HERC4 GOLGA4 ZMYM2 TEP1 SYNE1 UNKL SYNE2 MIER1 RGS18 TAF1 METTL3 VPS13D ZNF160 ITPR1 PPP1R12A ZNF451 PBRM1 IRAK4 PDE3B SFT2D2 FAM91A1 ZBTB14 ZBED5 TRPM7 RREB1 NCOA2 KMT2A LPP KMT2C JMJD1C NF1 TRA2A A1BG PCM1 CHD2 ORMDL1 SPG11 ATG2B EPG5 ERBIN UBR5 MFN1 UBR1 VCPIP1 ZNF136 ZMYM6 ZNF224 CLEC2D UBXN4 SCAF11 SUCO POGLUT1 SETX RABEP1 FBXO11 DMTF1 CCDC88A BCLAF1 BIRC6 ZCCHC10 PPWD1 ANAPC4 LATS1 ZNF24 SLC11A2 IREB2 OGFRL1 COX7B TIAL1 TOMM7 POGZ USP24 LYST ARID2 MGA ITSN2 MLLT10 ZFX LRIG2 C18ORF25 CLK4 REV3L MAN1A2 RNPC3 PTAR1 SLK UBN2 PHIP DENND4C CMYA5 YTHDC2 CCDC14 NHLRC3 DOCK11 RSL24D1 CLDND1 ZC3H6 ARFGEF2 ZNF131 PHF20L1 SLF2 DMXL2 PAXBP1 ASXL2 MED13 MRFAP1L1 RC3H2 SPATA13 CCDC82 CREBZF SACS STX2 ARHGAP12 MON2 BAZ2B LCOR PCF11 VPS13A GOPC TUT4 OTUD4 BRWD1 PRKAB2 NAA16 H1-3 H4C3 ARID4B FRYL ARAP2 IFTAP PATL2 FCRL1 DOCK10 KIF5B PNRC2 ETNK1 RBM25 OGA PRPF4B ZFC3H1 CEP85L ZNF776 CEP95 KIAA2026 EPM2AIP1 ZNF770 INO80D SFMBT2 SHLD2 PCMTD1 VPS13C CUL5 ANGEL2 EFR3A TENT2 UVSSA RABGGTB ITPR2 BPTF GSAP NKTR NHLRC2 PDS5A XPO4 KIAA1109 HMBOX1 DDX3Y CNOT6L LSM8 SLMAP RORA AFF1 KIDINS220 EXOC5 UBE2W MFSD8 TRMT13 SNX14 AP1S2 CTDSPL2 UBE3A ATAD1 TAOK1 NR2C1 HEATR5B KLHL9 C2CD5 ZNF638 ATXN7 ODF2L TMF1 OXNAD1 PKN2 SRSF10 RBM26 CEPT1 TRRAP PPP6R3 AGO3 CEMIP2 AMY2B PCGF3 TRIM33 ZFP62 NEPRO ARFGEF1 INTS6L ZNF700 ANKRD44 ZNF333 ZFYVE16 MRE11 N4BP2L1 KRR1 ZNF22 CCDC66 SCLT1 HSDL1 POLK TASOR BCLAF3 ZNF644 RELCH ZNF226 MAPKAPK5 ZNF736 RAB3GAP2 NSUN6 ZNF83 PRR4 DNAJC16 RBIS MARCHF6 POLG2 ZNF514 SLF1 ATP5MGL SS18L1 CASP8AP2 PABIR2 ERMARD Top 500 up genes for SARS-CoV-2 middle-stage infection in human female blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 CEP250 CANT1 RAD23B HSPA5 HYOU1 VCP PDCD1 CHPF CAPN2 TRIB3 MOGS MYO1D UBQLN4 CCND3 YIF1A ABL1 ZC3H18 RASA3 NF2 NDRG1 TPRN FURIN COQ8B NLRP6 HMOX1 SERPINE1 SLC27A4 TUBA1C ZDHHC5 RELA ACE ERBB2 HERPUD1 PCNT WFS1 NPLOC4 SMARCA4 TLN2 THOP1 PLEC LRRC8A SBK1 FGFR4 MGAT1 NCOA5 BAP1 SDC1 KRT18 IFI27 EFHD1 ADGRG1 KHSRP ATP10A TMEM184B POLG ANKRD52 NACC1 TMC6 RMDN3 RIC8A DAZAP1 SHC1 HS1BP3 STEAP3 NUMA1 TUBGCP6 PCNX3 PPP6R1 RETREG2 GGA1 LMNA EIF3B NDST1 PPP6R2 SLC38A10 NCLN SLC38A7 GLMP DHCR24 MYBL2 CCNA2 TK1 KNL1 SPAG5 VDAC1 MCM2 SHMT1 PAQR4 CDC6 BIRC5 EIF4G1 HDLBP TPX2 TBL2 CDC20 PKMYT1 MKI67 DTL NKIRAS2 TYMS MMP23B KIR2DL1 B4GALNT3 CD247 LRFN3 FGFRL1 RUNX3 FAM131B KIR3DL1 LLGL2 B4GALT2 CDKN1A CHTF18 ABCF1 FGFR1 CISH SNPH FAM20A FOXM1 TONSL PPP1R16A PAK4 JUP MROH6 FAM83F SLC7A5 BNC2 SLC4A2 LRP5 SLC34A1 MAFK DGCR8 RNF26 TCF3 EDC4 RAB11FIP3 CYHR1 SBNO2 ZAP70 SASH3 IL10RA CCNA1 ASF1B TCF19 CHEK1 AGAP2 CKAP2L CHAF1B NCAPD2 SLC29A3 IL2RB MCM5 TKTL1 ARHGEF39 CCNF NCAPG2 TBX21 PTPN7 CDT1 PHF19 XRCC3 NRIP3 TUBA1B IGFBP4 HPCAL1 JUN POLDIP3 PEX6 CDK16 CALR ARF1 PSKH1 FASN FSCN1 KIFC3 DGKQ CCR4 CCND2 RIMS3 SPON2 CLSTN3 NPDC1 FBXL16 CSRNP1 CYB561D2 WBP2 GYS1 GPKOW RNASEH2A DPP3 RPN2 DDB2 CDC25B MFAP1 RANGAP1 NOP14 MN1 HYAL1 TPST2 ARRDC2 SMIM1 DPH2 FANCG DHRS13 CTDP1 ADAMTS14 NUDCD3 NCR1 PRF1 LRRC14 POLR3H ANKRD55 DNASE2 RASD1 PACSIN1 SLC1A4 GRIK4 GSDMB CRABP2 PER1 MCM7 DCPS IDH2 LMNB2 LIG1 PILRB KPNA6 TPRA1 ST6GALNAC6 RASL10A KLHDC7B DUSP4 NAPA TRIM26 ENO2 LYG1 KLHDC8B RALGDS CHST2 TRIB1 PNMA3 TECTA GNA12 FSD1 IRAK1 PLA2G6 SARM1 SDHA FTSJ1 IKBKG IGF1 WIPI2 PARP1 TBC1D20 USP5 PARS2 NR1H2 BAK1 MAPKAPK2 PHGDH FADD ROBO3 SPP1 SLC35A4 CHMP1A CITED2 CLCN7 ABHD12 STK25 ARMC6 ABHD4 DDX54 TSPAN14 EHMT1 TRMU C14ORF132 SLC35C1 RASSF1 ECHDC2 AGPAT3 HTT WDR81 ULK3 DDA1 PLK3 IPO13 GLI4 PACS2 MLXIP LSS TTLL12 MVK FDXR ASB1 CAPN10 PIM2 CCDC71L PPDPF FOXK2 E2F4 RAPGEF1 RXRB LETM1 MFN2 NISCH URB1 EDC3 GAS6 LZTR1 TXNDC11 SGSM2 PCDH1 PRICKLE3 RPS6KA4 TAB1 PPARD PC ADD1 MTHFR SREBF2 CLPTM1L KEAP1 SRF CDKN2A CABYR ARHGEF37 KRT72 GALNT6 SPRED2 AKT2 HSF1 GPC1 ABCA3 RPTOR MEOX1 LRRC59 PRR5L VAC14 DAP ATP13A2 FOXP3 SPHK2 DNM2 CPTP ABCA2 PTBP1 GTPBP1 ABCB8 GALNT14 FZR1 RRP36 MRPL4 DHX37 HNRNPAB GEMIN4 CCDC137 GCN1 IFRD2 GRWD1 MLLT1 NOLC1 SLC35B1 MAP2K7 SP2 HDHD3 IP6K1 ZNF526 KDM5C FEM1A SYTL3 MFSD3 HS6ST1 PAGR1 GALNT10 GMPPB PIF1 PWP2 CSGALNACT1 ZP3 STOML1 ZNF579 FBXL19 ZNF672 CACTIN GTF3C1 RNF40 AARS2 RITA1 ECH1 HPS6 PFKP AP3D1 CCDC71 SMYD5 ZNF598 UBE2O RPAP1 ZBTB7A RECQL5 GPR161 CAPN15 CBX6 H2BC5 H1-0 ST3GAL2 KIF1C ILRUN DDX23 SBF1 GIT1 RBM19 USP35 SPEG SLC4A3 TAF6 SSBP3 C9ORF40 FAM222B DENND2D IFT140 ZNF213 NMT1 EIF4A3 SMG5 DDX51 COPS7A CLEC16A ASB6 SH3BP5L PTPRN VSTM2L ZC4H2 CCDC97 GATAD2A ZGPAT GDPD5 SH3GL1 KLC2 PTPN23 DHX38 MINK1 SNAPC4 EXOC7 WDR6 GPRIN1 ZNF777 SLC22A17 MON1A ABHD15 DENND1A CYB5D1 RNF157 KCTD17 SLX4 ZNF74 NUTM2B GINS3 CCNK ALKBH4 SLC25A19 BET1L FBXO46 POU5F1B MIEF1 DTX3 L3MBTL2 CALHM2 FAAP100 CTIF GPR19 KNDC1 MLC1 MAN2A2 SYT5 C20ORF204 CERS4 TMEM250 TEDC1 OPRL1 PAAF1 H2AX SPINDOC VRK3 PANK4 NMUR1 STARD8 MYBPH CARMIL3 CACNA1I YARS1 FBH1 KRT73 RUSF1 TUBB8B DGKK M1AP FAM50B H2BC9 PSMB11 WDR97 Top 500 down genes for SARS-CoV-2 middle-stage infection in human female blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 PPIL3 SUMO1 RPS27A PPBP EEF1A1 TBCA MPHOSPH10 RAB2A BIRC3 FGL2 NMI ATP5MG CXCL10 SLU7 NGDN GTF2F2 LARP7 RAB18 ING4 PSMC6 B2M REEP5 UTS2 FAU HSBP1 PMPCB NPM1 PPIG GHRL DNAJC19 DPH5 NAP1L1 FBXO3 MYNN PSMB1 NSMCE4A RIOK2 WDR89 ADH5 MPP7 ENY2 ASB9 ZFAND1 N4BP2L2 CAMLG NAE1 BCL2A1 ATP6V1G1 RPS20 XPA PFDN5 RPS17 SH3D19 RPL21 RPL35A ZNF253 RPL9 ARL3 RPL27 RPL41 RPS15A RPS24 TPT1 RPL6 RALGPS2 NDUFB2 RPS3A RICTOR RPL30 RPL23 RPL24 RPS25 RPSA RPL39 RPS13 ACOT13 RPS18 COX7C RPS29 AIF1 RPL31 RPL11 RPS14 RPS7 RPL7 RPS27 RPL27A NDUFB5 GLRX SEC11A ALCAM OPN3 CBWD1 NDUFS4 ADAMTS2 ATP5PB RPL26L1 ATP5F1C KLRG1 KLRB1 CLC LINS1 HINT1 IGBP1 ABCD3 RAB4A NUCB2 HERC2 MAP2K6 PSMA3 CYSLTR2 CD48 KLRC1 GIMAP7 SH2D1A MS4A6A CRTAM GZMA CD3D IFIT1 CLEC4A HMGB2 GLIPR1 GPR171 MYOM2 TXLNB EVI2A CLEC4D TNFAIP6 CASP4 CSTA PPA1 MITD1 RBP7 UQCRB TMA7 MYL12B SYF2 RPS23 COX7A2L RPL3 RPLP0 RPL5 EIF3E COX7A2 EEF1B2 SNRPD2 RPL26 RPS21 GDI2 RPL4 ARPC3 ARPC2 DNAJC8 PAIP2 NDUFB3 FNTA RPL35 SRP14 DYNLT3 RPL15 TOMM20 NDUFA5 RAB11A CAPZA2 ANXA1 TVP23B EIF4A2 NDUFA4 RBM7 SAT1 POLR2K CETN3 SUB1 VBP1 GTF2B EMC2 DBI SAR1B MRPS18C TMEM256 CBX3 LGI4 VCPKMT ZNF267 ZFP14 GIMAP2 LGALS2 TAF1D DPY30 SNRPG HAT1 ZBTB8OS PSMA4 ASNSD1 TXNDC17 CHMP5 NDUFAB1 MRPS33 TCEAL8 HMGB1 L3HYPDH SMIM20 MRPL13 SRP9 MAGOH COPS5 NIF3L1 RCN2 MRPS23 LYSMD2 EIF2A PCMT1 SSB ACTR10 PDCD10 RPAP3 SNX4 MRPL32 CMC1 HMGN3 ERH UBA3 HEBP2 NAA20 BEX2 SNRPE RPL34 CWC22 GPBP1 ZMAT3 SKA2 KRCC1 ZNF32 TNFSF15 TAF7 CENPC MAGOHB MKKS TRIAP1 P2RY14 S100A8 AVIL CASP1 ADAMTS6 BID DCP2 GPR18 HLA-DMB COL9A3 C3ORF33 TMEM126B C2ORF76 IFT74 CD302 BET1 TNFSF13B ZNF302 SLC35A1 RPL22L1 SMC5 CCDC91 DBR1 ESCO1 HLA-DRA FAS RABGAP1L SRGN MAP3K7CL SERP1 CD52 RPS6 COX6C CALM2 LPAR6 ZNF280D KBTBD3 KHDRBS2 ENTPD1 SERPINB8 DSC2 AIMP1 POT1 HIKESHI PHF5A VPS29 OLA1 PFDN4 SEM1 IDI1 CARD16 TAX1BP1 TSNAX STXBP3 TSN SF3B6 STARD3NL RARS2 TAF9 ACTR6 IFT20 FAM32A HPF1 TMEM167B CALHM6 ATG3 BLOC1S2 CIAO2A ATP5PF CLNS1A COMMD6 C11ORF58 GGCT ZNF230 RPGR DCAF13 ZNF14 CEP63 KIN NFYB ZC3H15 GNL3 DPM1 WDR75 CBWD2 BRIX1 PTPN2 CWC15 MDGA1 CMC2 MCTS1 MIER1 GMFG DAPP1 NBN ANKRD22 GAPT UTP6 HLA-DOB COP1 PUM3 SNX2 KDM3A NF1 FXR1 IFT57 R3HCC1L FAM227B DYRK2 PRKAA1 BNIP1 BANK1 DRAM2 RNFT1 FBXW7 CD1C MRPL40 VCPIP1 ZNF613 VPS50 RBAK ZNF227 ZNF383 ITGAE TBC1D15 TRIP11 TAF2 FLVCR1 HSPA14 SLC22A15 POLB CCNH ZCCHC10 RAG1 WDR70 TMEM59 TXNDC9 COX7B NDUFS5 HNMT TIMMDC1 NUDT21 TOMM7 C18ORF25 PDZD2 TTC39B CLK4 MRPL3 MPV17L MIER3 SLK CCDC50 RSL24D1 PYROXD1 ZNF277 GALC BTF3L4 HDDC2 MRFAP1L1 CCDC82 DMAC1 RPL39L NMD3 SNRPD1 NSA2 PIAS2 FRA10AC1 LSM3 SMIM26 TMCO1 SVIP CNIH4 ZNF587B SMIM30 ERGIC2 PYURF RETREG1 TCTN1 MED21 GRHL1 ZNF770 BTBD10 PCMTD1 MTERF1 EML6 TSPAN2 CRYZL1 DUSP11 RABGGTB NUP35 NIFK CFAP36 LSM8 WDR61 CASK MRPL45 POLR1E WASHC3 EAPP COA5 LYRM7 ZDHHC2 MED7 CEP57 SNX14 AP1S2 MKLN1 ATAD1 RNF144B MRPL22 CCDC59 ELP2 ZNF638 FAM204A CWF19L2 ZNF480 HELQ SS18L2 PARL MRPL48 MRPS31 NSMCE2 PPP6R3 CRBN TRIM33 ZNF781 ARL14EP AKTIP RNF141 OARD1 ZNF586 ANKRD44 ZNF354A UPF2 NAPB CUTC MOCS2 HENMT1 NDUFAF8 RSL1D1 SAYSD1 TASOR CCSAP CDC37L1 ZFP3 ZNF83 CCDC65 LYRM1 MTIF3 VSTM1 GPATCH11 RBIS NKAPD1 MIX23 ATP5MJ POLG2 NUP42 TRMO IRAG2 LRRC7 Top 500 up genes for SARS-CoV-2 late-stage infection in human male blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 UBB CD79B BCL2L1 MAPK3 CAPN5 PRKCZ CTDSP1 SQSTM1 FBXW5 PRKACA UBXN6 PPP2R1A MAP7D1 SLC9A3R1 PTCRA TLE5 UBXN1 AATF PKM FURIN TUBB4B ECSIT KCNQ1 HSPB1 AP2M1 ANXA11 GPX1 CALM3 UBA52 TUBA1C NUCB1 RAD23A TUBA4A NUTF2 CYB5R3 MGAT4B BAG6 NDUFB9 SHARPIN TGFB1 YWHAH FBP1 CHMP2A VWCE SLC25A39 KLF1 RILP SCYL1 MGAT1 C20ORF27 SGTA DEDD2 ENO1 BAP1 RPLP2 FTL TAGLN2 SMARCD2 PNPLA2 ARID5A LSP1 PTPA RIC8A GSK3A UQCRC1 PRKCSH PGD GRINA RPS6KA1 PNPLA6 SF3B4 FKBP8 SNRPB GNB2 DNAJB2 SUMF2 PPP6R1 RETREG2 DOK2 EIF3B TKT EMP3 ARHGDIA TOLLIP WDR13 RHBDD2 TIMP1 MRPL37 C1ORF162 HADHA NDUFS7 NDUFAF3 CAPNS1 MPND GAPDH G6PC3 HDLBP SNX8 TPI1 KLF16 PHOSPHO1 ABCF2 B4GALT3 AQP10 ACTB HMGA1 CAPN1 SLC7A5 TFIP11 CTNNBIP1 MAP2K3 CDK2AP2 BIN1 RNF26 TRIOBP CCDC9 MED25 DYRK1B ZNF628 PACS1 WDTC1 AP2A1 TMEM63B ZNF385A RXRA SCAF1 AKT1S1 EPN1 HCLS1 SASH3 SELPLG HCST MCM5 ARHGDIB RAC2 CORO1A COTL1 ACKR1 HBB SLC4A1 NPRL3 CPNE5 DAXX PIM1 NINJ2 DBP TMCC2 RPL28 GNAI2 RPS28 PFN1 TNS1 CNN2 TUBA1B YBX3 CHMP4B EIF3G ADIPOR1 HPCAL1 RNF187 EEF2 RHOG CAPZB PLVAP GSTP1 NDUFA3 CLDN5 P4HB BCAP31 CST3 SNX17 MDH2 VPS28 PPP1CA SH3BGRL3 HNRNPUL1 JUND NDUFB11 HCFC1R1 VIM CD74 OAZ1 STUB1 ADRM1 TALDO1 MRPL28 FXYD5 AQP1 CFL1 ARF1 CDIPT MXD4 GPI EHD1 PSKH1 SELENBP1 EDF1 EFHD2 TPRG1L MARCKSL1 GUK1 S100A10 CD151 NDUFB10 PGLS ANK1 TSPAN18 MRC2 NATD1 TP53I11 DMTN PDLIM1 PDZK1IP1 UBE2M WBP2 RBM42 CUTA SRM POLD2 ATP6V0D1 SLC25A11 SF3A2 CCDC124 PPP1R7 PPP1R18 YIPF3 POLR2E MGLL NELFE SLC10A3 RUVBL1 DYNLL2 TUFM CUEDC2 RAB1B CHTF8 NUDC APOBEC3C VPS51 FOXO4 SURF2 VEGFB HDGF GAS2L1 B3GALT4 CSRP1 SNAPC2 EMD TMEM115 MUL1 PCSK1N MAP3K14 C6ORF47 PIGT CSK SMOX TSPAN33 GP9 NFE2 PTMS BTBD2 TESC GYPC RAB11B METRNL MED22 ST3GAL1 UCP2 ZBED1 CARM1 MLF2 TAF15 GMPR VAT1 ALDOA NRGN BLVRB GPSM3 EIF1 MYL9 PTPN6 R3HDM4 ILK HLA-DPB1 HBA2 GFI1B GNA12 PRDX2 IRAK1 PSMC4 GATA1 SDHA STX5 TRAPPC1 TADA3 UBL4A ACTR1A LYL1 TNIP1 RIN3 HBA1 ARF5 BSG CLPP GNAS MFSD2B SPRYD3 HMOX2 PPP4C NR1H2 UBALD2 ARAF PRPF6 HAGH SLC35A4 SZRD1 CCDC92 CHMP1A CNPPD1 CMTM7 CLPTM1 APRT CD99 ALDH3B1 ALKBH5 MPST MID1IP1 SUV39H1 IRF2BP1 PLEK2 ALDOC PINK1 ZNF524 RALY VPS18 HDAC5 MAZ RNPEPL1 ARFGAP2 PTPN18 MFNG G6PD PPDPF PARVB E2F4 SLC38A5 DAPK3 INPP5K NCAPH2 VPS37B TSSC4 PSMD2 GUCD1 MAF1 XRCC6 UNC45A RNF123 FDFT1 WDR1 USF2 ADD1 CDC34 JAZF1 YIPF2 PTP4A3 AKT2 MCOLN1 HSF1 ATG101 PRR5 DAP STK11 FOXP3 SIRT2 CPTP SNAI3 RANBP10 PSMF1 OSBP2 CRAT PPP1R9B PPP2R5D BRMS1 PDAP1 PPM1G RBM38 FZR1 THAP4 PRCC POLDIP2 RPUSD1 SHMT2 MRPS34 AKR7A2 GRK6 PRDX6 MAP2K2 SLC48A1 MAP2K7 DYNLRB1 TPGS2 POLR2L YY1AP1 GPS1 JMJD8 SLC25A1 ISG20L2 RHOF MICAL2 CARHSP1 NFIX ZBTB45 RNF40 ZNF787 ABHD14B DNAJC4 EEFSEC LHPP ASMTL PPP1R11 UBL7 JPT1 ECH1 APEH FARSA C11ORF68 SEPTIN9 ZNF428 CCDC69 HIRIP3 CD99L2 EIF6 EHD3 ILRUN PKN1 SF3B2 RNF10 ATP5F1D ST6GALNAC4 HDGFL2 CIZ1 AGPAT1 UBALD1 SHISA4 CENPB ELOF1 SLC6A8 ASCC2 FAXDC2 TANGO2 DPM2 CDIP1 PRPF31 POLL ZNF213 GTF2F1 EPB42 FBXW4 TRAF7 SLC25A6 SART1 CHMP6 DCTN1 SH3GL1 PUF60 PAF1 CTDNEP1 ACD ZNF362 ZNF777 OXER1 ZNF768 GET3 MCRIP1 RUNDC3A TBC1D25 BORCS6 NT5M RNF220 ZER1 CERS4 NELFB TMEM250 RANBP3 CMTM5 NAA60 PCIF1 ZDHHC3 FAM174C SGF29 H1-10 YJU2 SLC66A2 MMP24OS SEPTIN5 SARS1 MARCHF2 MPIG6B BBLN MYG1 Top 500 down genes for SARS-CoV-2 late-stage infection in human male blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 PPIL3 TIMM8B FAM8A1 BIRC3 GCC2 NIN CNTRL WASHC4 DDX5 TBK1 SLU7 SLC30A9 JAK2 LARP7 TTN UHRF2 ATM PSMC6 BIRC2 ADAM17 MYCBP2 RBM41 ITGA4 ELK4 AKAP9 PPIG USP15 TMED5 MAP3K1 LNPEP CASP3 DPH5 CHD1 NR3C1 USP34 VPS13B RBM39 TMEM30A ABHD3 PAIP1 ZFAND1 N4BP2L2 BCL2A1 RPS17 RPL35A RPL9 ZEB2 RPL27 FYB1 RPS15A RPS24 TPT1 NFAT5 ZNF91 RPS3A RICTOR RPL23 TET2 UTRN RPL39 RPL31 RPL11 TC2N RPS7 RPL7 TTC14 SEL1L TM9SF3 CMTM6 GLRX ALCAM HINT1 TGFBR1 PIK3CA SRSF1 APPBP2 USP9Y MEF2A SH2D1A PTPRC CLEC7A APOL6 EVI2A VCAN SAMD9L GCH1 MITD1 SP110 UQCRB LAMTOR3 TMA7 PPP1CB RBMS1 EEF1B2 LUC7L3 RPL26 ZNF780A RAP1B TRAPPC6B RHOQ DDX3X MBNL1 SP3 DHX15 NDUFA5 CHORDC1 CCNL1 CAPZA2 FNDC3B TMEM260 EIF4A2 NDUFA4 VBP1 ATP2B1 RPS27L SAR1B CD164 SLC38A2 DEK CBX3 CLEC2B C21ORF91 LRRK2 VCPKMT ZNF267 ZNF292 GIMAP2 FEM1B TAF1D BTAF1 SNRPG HAT1 PSMA4 ASNSD1 CHMP5 TMX1 SRP9 NOP58 SMARCA5 SERINC1 RPS6KA3 VAMP7 HMGN3 PAPOLA UBA3 STAG2 RPL34 RB1CC1 SLC25A46 USPL1 GPBP1 RSRP1 CUL4B OGT ARGLU1 KRCC1 SRSF2 NUFIP2 SRSF7 TAF7 CREBRF SRSF6 CEP192 CD46 UHMK1 CD47 NECAP1 TAP2 S100A8 SLFN5 DCP2 MORC3 PIKFYVE GOLGA8B PRPF39 TMEM126B RECQL LPGAT1 ARID4A SMG1 TIA1 XRN1 SLC35A1 ANKRD49 DDX60L ZRANB2 UFM1 SAMD9 NIPBL CCDC186 ATRX LTN1 PRKACB ANKRD12 BOD1L1 PNISR NAA25 RSF1 BAZ1A SMCHD1 FAS FMR1 COG3 RAB8B SF3B1 XPO1 SRSF11 COX6C ROCK1 ADAM10 PUM2 LPAR6 ZNF397 PDE7A PPTC7 CLK1 IFNGR1 RHOT1 DHX36 PHF5A VPS29 EXOC1 UBE2V2 SEM1 SACM1L RANBP2 TANK IDI1 THAP12 USP33 CREB1 DPP8 DICER1 FAM111A TAX1BP1 STX7 TMEM167A TSNAX NDUFB1 FKBP3 TAF9 ATG12 CYLD RAP2C UBA6 AMN1 CMPK1 BTBD1 CAPZA1 CGGBP1 C6ORF62 CLNS1A COMMD6 ZC3H11A ZNF230 DNAJB14 CARD8 PHC3 DCAF13 DIP2A KTN1 NEMF RBBP6 BBIP1 U2SURP ZC3H15 ACSL4 GNL3 CEBPZ STT3B USP16 WDR75 CCAR1 TMEM123 AKAP10 PTPN2 CCNT2 HERC4 GOLGA4 MIER1 TFEC DAPP1 NBN RGS18 PPP1R12A ZNF451 IRAK4 FAM91A1 ROCK2 ZBED5 PTPN11 KMT2C JMJD1C SMC4 TMEM168 COPS8 RO60 ORMDL1 ERBIN SENP6 NRAS RC3H1 ZNF12 VCPIP1 VPS50 RBAK ZNF224 ZNF26 SNX13 CLEC2D ABCA5 UBXN4 SHOC2 TBC1D15 TRIP11 SCAF11 ZDHHC17 AP5M1 SETX RABEP1 FBXO11 ELMOD2 MAP3K2 WSB1 UGCG DMTF1 CCDC88A BCLAF1 PPWD1 RWDD1 ANAPC4 ST8SIA4 ZNF24 IREB2 OGFRL1 CSGALNACT2 COX7B NUDT21 MSL3 TOMM7 USP24 LYST ITSN2 GPATCH2L C18ORF25 CLK4 MRPL3 MYSM1 MAN1A2 RNPC3 PTAR1 SLK STK17B PHIP ABHD13 NHLRC3 DOCK11 RSL24D1 PYROXD1 TMX3 C9ORF72 PHF20L1 DMXL2 MED13 RASA2 TRAPPC8 RC3H2 SPATA13 CCDC82 CREBZF STX2 PPP4R3A ZZZ3 MON2 BAZ2B PCF11 OTUD4 BRWD1 PRKAB2 H1-3 MRPL50 ARID4B FRYL ARAP2 SVIP ATL3 RESF1 ERGIC2 ATP11C KIF5B PNRC2 RBM25 OGA EIF5 PRPF4B ZFC3H1 CEP85L ATAD2B CEP95 CHD9 INO80D RLIM PPP4R2 TNPO1 SHLD2 PCMTD1 VPS13C ANGEL2 DNAJC10 ACAP2 TENT2 KLHL8 OPA1 ATP11B TBC1D23 RABGGTB ITPR2 BPTF NKTR PDS5A BRWD3 KIAA1109 RAB12 DDX3Y CNOT6L RAD50 LSM8 EIF1AX SLMAP PPP1R21 AFF1 KIDINS220 COA5 PNPLA8 FAR1 UBE2W PGGT1B C1GALT1 MOB1B FAM76B BLOC1S6 SPOPL CEP57 TRMT13 SNX14 AP1S2 COPS2 ZNF518A SREK1IP1 EXOC6 TAOK1 ZNF761 USP47 KLHL9 C2CD5 ZNF638 PRPF40A TMOD2 ATXN7 FAM204A TMF1 PKN2 SRSF10 RBM44 MED28 PPP6R3 ZNF33A CRBN TRIM33 INTS6L RIF1 ZNF493 ARL14EP LARP1B ZNF585B TCEAL9 PPP4R3B ALG13 ANKRD44 ZNF333 ZFYVE16 MRE11 N4BP2L1 KRR1 ZNF22 SCLT1 TASOR RELCH ZMAT1 CCSAP ZNF226 ZBTB37 RAB3GAP2 ZNF83 SS18 RBIS ODR4 CERT1 MARCHF6 MARCHF1 Top 500 up genes for SARS-CoV-2 late-stage infection in human female blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 MYH9 SPTB CEP250 CANT1 SUN2 CAPN2 MAP7D1 SPATA21 GCC1 UPF1 UBQLN4 RNPEP ABL1 TPM3 TMBIM1 ZC3H18 NDRG1 FURIN TLE3 NLRP6 NFKB1 CLDN15 ZDHHC5 RELA SF3A1 UBAP2L BAG6 ARHGEF11 NPLOC4 PXN BRD4 GNB1 MSN PI4KB CCDC86 DIAPH1 EVL HBM FRMD8 PLEC STAT6 SBK1 SF1 CPT1A PNRC1 SLC2A1 KRT8 NEDD4L TTC22 STIM1 TMEM94 KHSRP TMEM184B SYMPK POLG OGDH ANKRD52 ARHGAP30 TAOK2 GLYR1 PIEZO1 TMEM127 ZNF316 SHC1 INPPL1 NUMA1 TUBGCP6 PCNX3 LDB1 USP19 GIGYF1 LRP10 MYADM CAD KHNYN PPP6R1 RETREG2 PIP5K1C CIC ZSWIM8 PSD4 NDST1 HK1 SELENON ITGA5 CLUH PPP6R2 SLC38A10 NFE2L1 LRFN3 C16ORF54 CXCR2 RUNX3 KLF2 ZNF185 ABCF3 PKD1 STAT5A ZNF707 CNOT3 PLCD1 BCL9L ZNF687 SLC7A5 EPHB4 ITPR3 CLSTN1 SLC4A2 AXIN1 DVL2 ARHGAP1 ELF4 MAFK DGCR8 EDC4 PHF12 SLC16A5 KMT2B WDTC1 RAB11FIP3 RERE RNF44 CBX4 TNK2 TRIM8 CSNK1D ZFAND3 RXRA TBL1X NUAK2 FBRS PITPNM1 BRPF3 MNT ZNF646 ULK1 SBNO2 MIDN ZNF710 ATG2A TNRC18 PRR12 ERF SASH3 IL10RA AGAP2 IL18BP LCP2 IL2RB PIK3R5 PREX1 POLE PTPN7 PHF19 CHAF1A EHD4 SRSF4 ZFP36 LASP1 TNS1 HPCAL1 PCBP1 JUN POLDIP3 SH2B1 LITAF HNRNPUL1 GLUL PEX6 CAMTA2 TEX261 FAM53B MKNK2 PSKH1 FASN RASSF5 MYO18A KDM6B DGKQ CSF1 NATD1 ARHGAP25 CMIP PDE4A DMTN TMEM120B SKI BHLHE40 WBP2 GYS1 PPP1R18 CERS2 CHTF8 WBP11 CDC25B MFAP1 FXR2 LENG8 FOXO4 ARRDC2 TRIM41 SMIM1 CTDP1 ANKRD9 ADAMTS14 NUDCD3 LRRC14 ANKRD55 WDFY4 DHX16 CASC3 LIG1 ST3GAL1 NDRG3 ZBED1 CARM1 ST6GALNAC6 PPP1R10 RASL10A SRRM2 JADE2 SH3KBP1 TRIM26 ENO2 PACSIN2 ACTN1 SNN MAST3 RALGDS ADAM19 CARD11 P2RY8 REXO1 KCNH2 PLA2G6 RAB35 HPS1 GPR132 IKBKG PIK3CD ARHGAP45 BCR WIPI2 TBC1D20 RAB5B ELL MAPKAPK2 STK10 SLC35A4 UBE2R2 ALKBH5 MID1IP1 NDE1 ABHD4 TSPAN14 XYLT2 EHMT1 TRMU SLC35C1 KLHL21 MEF2D WDR81 ULK3 PLEKHM1 DDA1 PLK3 FLII GLI4 PACS2 SLC39A13 LSS TTLL12 TAF1C BTBD9 NCOR2 POLR2A PANX2 FBRSL1 WIPF1 PIM2 PPDPF MADD HDAC7 FOXK2 E2F4 MYO9B CC2D1B RAPGEF1 MAP4 RXRB LETM1 MFN2 SLC9A1 PLEKHM2 PLXNA2 ABR XPC NISCH TBCD LZTR1 SGSM2 PRICKLE3 RNF123 TMPRSS6 WDR1 ADD1 SPOCK2 SREBF2 SRF ELK1 PLXNA3 SMARCC2 ZBTB4 GALNT6 MAPK7 AKT2 MYO1C ABCA3 ATP2A3 AP3B2 RPTOR AMBRA1 LRRC59 PRR5L CRTC2 DAP WWP2 FOXP3 DNM2 TECPR1 HRH2 PTBP1 GTPBP1 RNF4 OSBP2 PPP1R9B KAT7 RBM38 FZR1 MLLT1 CDK12 AKNA ZNF142 SP2 CYB5R1 ATXN2L ZC3H4 DPF2 YY1AP1 FOXJ2 GMEB2 ATF7 SPATA2 ZNF335 GGA3 IP6K1 ARID3B EPS15L1 KDM5C SMG7 MRM1 ZSWIM4 KIF21B SYTL3 RBM14 CAPS OSBPL7 HS6ST1 CHST7 GALNT10 MICAL2 KIF3C LPCAT3 PHRF1 RAVER1 CACTIN GTF3C1 RNF40 INTS1 TMEM104 AARS2 SZT2 ZNF341 KREMEN1 DCAF11 ZNF592 MRNIP ZMIZ2 PFKP SETD1A TJAP1 AP3D1 ZNF598 UBE2O RPAP1 RECQL5 AHDC1 BICRA CAPN15 CBX6 RFX1 JOSD1 CUL9 TM9SF4 ILRUN PRRC2A DDX23 SBF1 AP2B1 GIT1 MLLT6 SLC12A4 TAF6 COPS7B DAB2 C6ORF136 FAM193A STX1A FAXDC2 TANGO2 RAB11FIP4 ZNF213 NMT1 SMG5 DDX51 CLEC16A STK11IP SH3BP5L FAM53C TLNRD1 WIZ KLHL26 ATN1 TRAF7 CCDC97 GATAD2A CROCC DCTN1 MED15 KLC2 PTPN23 DHX38 MINK1 EXOC7 WDR6 ADCY3 PROCA1 DLGAP4 SAMD4B CHERP ZNF777 ELMO1 SLC22A17 MON1A ABHD15 SLC45A1 GALT DENND1A CYB5D1 SH3RF3 FAM229A KCTD17 SLX4 MED12 CCNK POM121C BET1L FBXO46 IQSEC1 DNAJC5 MAPKBP1 TBC1D25 L3MBTL2 MAN2B2 BAHD1 TULP3 DVL3 ADAMTSL5 ZER1 WIPF2 MAN2A2 C20ORF204 TMEM250 IQCN SLA2 VRK3 KCTD21 PANK4 RBM23 NLRP12 ZNF384 PGGHG FBH1 FHIP2B MARCHF8 MINDY1 IRAG1 H2BC21 NPIPB13 ASMT Top 500 down genes for SARS-CoV-2 late-stage infection in human female blood from GSE161731 To define the host peripheral blood transcriptional response in subjects with SARS-CoV-2 infection, RNA-seq was performed on whole blood samples from individuals experiencing 3 different stages of COVID-19 (early, middle, late), and compared with uninfected healthy control subjects. Associated with these 2 publications: McClain et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nat Commun 2021 Feb 17;12(1):1079. PMID: 33597532; and Wang et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Med 2021 May 17;13(1):83. PMID: 34001247 PPIL3 SUMO1 RPS27A TIMM8B EEF1A1 TBCA MPHOSPH10 ERLEC1 ATP5MG EIF2S1 EXOSC8 ACADM SLU7 RALA NGDN RBX1 NDUFAF2 SCCPDH GTF2F2 HSP90AA1 LARP7 RAB18 PSMC6 BIRC2 B2M REEP5 SRP72 HSBP1 PMPCB EIF4E NPM1 PPIG PPIA CASP3 DPH5 OXSM MYNN PSMB1 NSMCE4A RIOK2 WDR89 ADH5 PAIP1 PMS1 ENY2 ZFAND1 CAMLG NAE1 BCL2A1 ATP6V1G1 RPS20 XPA PFDN5 RPS17 RPL21 RPL35A ZNF253 RPL9 RPL27 RPL41 RPS15A RPS24 TPT1 RPL6 RPS8 NDUFB2 RPS3A RICTOR RPL30 RPL23 RPL24 RPS25 RPL39 RPS13 RPS18 COX7C RPS29 AIF1 RPL31 RPL11 RPS7 RPL7 RPS27 RPL27A NDUFB5 SEC11A EAF2 TNFRSF17 CBWD1 NDUFS4 ATP5PB RPL26L1 OSTC JCHAIN ATP5F1C MTERF2 KLRB1 TRAT1 HINT1 IGBP1 ABCD3 NUCB2 PSMA3 SMC2 KLRC1 GIMAP7 SH2D1A MS4A6A GZMA KIF20B CLEC4A HMGB2 GPR171 KYNU EVI2A CLEC4D NT5C3A CSTA PPA1 RNF7 SPTSSA UQCRB TMA7 PPP1CB TXN SYF2 RPS23 COX7A2L RPL5 EIF3E COX7A2 CCT2 EEF1B2 LUC7L3 SNRPD2 RPL26 RPS21 GDI2 RPL4 PSMC2 ARPC3 DNAJC8 PAIP2 EID1 NDUFB3 RPL35 SRP14 DYNLT3 RPL15 TOMM20 NDUFA5 NDUFA1 DNAJA1 CAPZA2 NDUFA6 RBM3 ANXA1 LXN TVP23B NDUFA4 POLR2K CETN3 SUB1 VBP1 GTF2B EMC2 NUCKS1 METTL14 DBI SAR1B MRPS18C PIN4 CBX3 ESF1 ZNF267 GIMAP2 TAF1D DPY30 SNRPG HAT1 ZBTB8OS PSMA4 ASNSD1 TXNDC17 CHMP5 NDUFAB1 PTRHD1 MRPS33 TCEAL8 ATP6V1D HAUS1 HMGB1 TMX1 YPEL5 UBE2N MRPL13 NFU1 SRP9 MAGOH COPS5 TMEM126A PSMD10 TPRKB NOP58 UQCRQ ANP32E NIF3L1 MRPS23 VRK1 ATG5 NOC3L EIF2A PCMT1 SSB ACTR10 PDCD10 VAMP7 RPAP3 SNX4 MRPL32 UQCRH HMGN3 SEC11C ERH MRPL1 UBA3 NAA20 STAG2 BEX2 GNL2 SNRPE RPL34 GPBP1 GFM2 SKA2 KRCC1 ZNF32 TAF7 NIPSNAP3A MKKS MRPL47 TRIAP1 SLIRP S100A8 BTLA GPR18 TMEM126B SMC3 SEC62 IFT74 BET1 SLC35A1 RPL22L1 UFM1 FBXO33 SMC5 CCDC91 ANKRD12 BBS4 ESCO1 HLA-DRA NUDCD1 ZBTB33 SRGN CD52 RPS6 COX6C SNRPB2 CALM2 LPAR6 ZNF280D ENTPD1 GRPEL2 AIMP1 COPS4 POT1 HIKESHI GLRX3 PHF5A VPS29 YEATS4 OLA1 PEX2 SEM1 PPA2 GTF2H5 IDI1 CARD16 TAX1BP1 TSNAX STXBP3 SF3B6 STARD3NL RARS2 FKBP3 TAF9 PLRG1 ACTR6 IFT20 APIP HPF1 CALHM6 ATG3 CAPZA1 ATP5F1E BLOC1S2 ACAT1 CIAO2A ATP5PF CLNS1A COMMD6 ATP5PO C11ORF58 ATP5ME GGCT ZNF230 DCAF13 ZNF14 KTN1 DDX50 KIN NFYB ZC3H15 RPF1 DNTTIP2 GNL3 DPM1 DNAJC21 CEBPZ USP16 WDR75 CBWD2 DNAJC2 BRIX1 HSPB11 PTPN2 MRPL33 CWC15 POLE4 CMC2 MCTS1 GMFG RGS18 UTP6 METTL21A PUM3 SNX2 ZBED5 CDC27 RRAS2 FXR1 IFT57 TMEM168 DRAM2 MRPS22 MRPL40 FBXO4 ZNF613 VPS50 RBAK ZNF227 TBC1D15 ZDHHC17 ELMOD2 ABCB7 CYP2R1 NAA15 DNAJC15 POLB CCDC88A CCNH ZCCHC10 RWDD1 TMEM59 TMEM14C DUSP12 TXNDC9 COX7B NDUFS5 RTRAF TIMM17A TMEM70 HNMT METAP2 MFSD1 TOMM7 SKIL MRPL3 MRPS21 EBAG9 RSL24D1 PYROXD1 ZNF277 GALC CCDC90B BTF3L4 HDDC2 TRMT10C CCDC82 DMAC1 RPL39L DLG1 NMD3 SNRPD1 KYAT3 NSA2 FRA10AC1 MRPS14 LSM3 ZCCHC17 TMCO1 MRPL50 ARID4B SVIP METTL5 SMIM30 ERGIC2 RETREG1 ECHDC1 VMA21 MED21 EIF3M CEP85L ZNF845 PPP4R2 SHLD2 THAP5 MTERF1 MTREX FASTKD1 RABGGTB NUP35 TRAPPC13 NIFK CFAP36 DCUN1D5 VAMP4 LSM8 WDR61 UPF3B MRPL45 ZFAND6 WASHC3 PNPLA8 MED7 CEP57 SNX14 AP1S2 COPS2 MKLN1 MRPL22 POLR3F CCDC59 PTRH2 EIF2S2 LSM1 DLD ZNF181 FAM204A ZUP1 EED CWF19L2 ZNF480 HELQ SS18L2 PARL MRPL48 MRPS31 NSMCE2 CRBN TRIM33 ARL14EP OARD1 MDM1 ZNF354A CUTC MOCS2 HENMT1 NDUFAF8 ZNF22 POLR3GL C12ORF4 TASOR ZNF226 CDC37L1 PUS7L TATDN1 MTIF3 RBIS NKAPD1 MIX23 ATP5MJ NUP42 MARCHF1 NDUFAF7 METTL18 ZNF563 SMIM10L1 OBI1 ATP5MK Top 500 up genes for COVID-19 mild disease in human NK cells from GSE165461 Gene expression patterns of Natural Killer (NK) cells were compared between healthy human subjects and COVID-19 patients. EEF1A1 RSRC2 UBE2D2 CD14 SUMO3 IDE ANPEP CTSL VDR UBXN6 LILRB2 DDX21 SLC7A7 TLR4 SLU7 CXCL16 YWHAE BRAF ADAM9 DYNC1H1 PMEPA1 NCL FAR2 HSP90AA1 SIRPA NFKB1 HMOX1 CSNK2A2 EIF2AK2 SRP72 ITGA4 OASL BRD4 CXCL2 ING3 NAT14 USP7 MX1 CHD1 PTK2 RCOR1 ARHGEF12 MTMR14 MPP7 RBM39 BCL2A1 BTF3 BRF1 MT2A PERP TENT5C NINJ1 RGS2 IFI27 NR4A2 MTRNR2L8 MT1E MTRNR2L12 MARCKS GALNT5 APOBEC3A MT-ND2 RPL23 SLC2A1 ADAM28 CD300E CCL4L2 TAB2 SRRT RELT RMDN3 HBEGF GRINA EMC10 TBC1D2B EMILIN2 CORO1B LRP1 B3GNT7 LMNA SMAD7 RARA SLC11A1 AREG IFI44 ELL2 LHFPL2 LGALS1 MAFG MAFB E2F1 EPSTI1 RGS16 RRAS PPARGC1B ACVR1B RASGEF1B CXCL8 YES1 MLF1 TOPORS G0S2 CDKN1A HINT1 SLC2A3 ABCF1 CDV3 PIK3IP1 SLC2A8 PLAUR OSM MED23 WHRN PAK4 JAG2 SLC7A5 EREG ATF3 GABARAPL1 MAP2K3 HIF1A UBE2Q2 TFE3 BCL3 FCN1 FOSL2 CSNK1D EME2 BRPF3 ULK1 ATG2A DBF4 CKAP2 HMGB2 CLEC7A COTL1 CFD S100A9 KYNU HBB VCAN SOCS3 TREM1 NAMPT C5AR1 NRIP3 AHR SRSF4 THBD SGK1 NFKBIA SPARC DRAM1 BTG1 RPL26 MYH10 IFI44L ARPC2 S100A6 JUND EPC2 ITPRIPL2 DHX15 CSF1R PSAP FAM53B MXD4 JDP2 RBM3 SLC25A3 IVNS1ABP SAT1 WDR45B SUB1 YTHDC1 SUPT5H ATP2B1 NUCKS1 KDM6B SAMSN1 ZC3H12A DDIT3 DUSP8 SLA EGR2 NR4A3 S100A12 B3GNT5 KBTBD8 TNFAIP3 ZNF267 SKI BRD1 DUSP5 BHLHE40 TAF1D ZNFX1 SLC25A33 MSL2 UBE2A SRM CKB YPEL5 CHMP4A AHCY GOLT1B SDC2 TOMM34 PTMA DCTN6 TUBB6 MMADHC ETF1 RPL32 SF3B5 RB1CC1 MXD1 GPBP1 SERINC5 HSPD1 DUSP10 PDE4B SRSF2 IK SCAF8 DENND5A ODF3B REL S100A8 SMOX CREM PCGF5 MAP3K8 FPR1 SLC1A4 CDKN2C SLC43A2 RP2 IFI6 PER1 SLC20A1 FAM111B ZNF791 MED29 GMCL1 SNRPA1 METRNL C17ORF67 GORAB TOP1 PRRC2C SECISBP2L CKAP4 PIK3R1 CCDC173 ANKRD12 ST6GALNAC6 BOD1L1 RSRC1 ESCO1 CDK17 RELB PMAIP1 DUSP4 N4BP1 RAB8B SRGN ACTN1 MMD BLVRB SNN SARAF SRSF11 RPS6 COX6C CALM2 CD44 PTPRE TRIB1 LANCL2 CLK1 CHKA CD70 HBA2 ETV3 CHN2 PDE1B IFNGR1 CGAS RAD21 PSMD7 RANBP2 LILRA5 HBA1 DICER1 RECK CXCR4 TNFRSF1B RNF11 NFKB2 UBAP1 TSN TRAPPC10 CD82 MAPKAPK2 GDE1 PSMC3 WIPI1 AKIRIN1 SNRNP27 TM9SF1 SYAP1 IRAK3 RDH16 ZNF34 ATP1B3 C9ORF78 CLN3 GAB2 XPNPEP3 USP36 HELZ EML4 NEMF NSRP1 GPCPD1 SMIM3 ZC3H15 EIF3J ZNF326 DPM1 USP16 SOCS6 DNAJC2 RIOK1 PMF1 HAPLN3 PPP1R3B CLTB POLR2A SMAP2 TTC7A TSPYL2 GNL1 PLEKHM2 RRP7A SREK1 ZNF451 SPHK1 ACOT9 CHD8 SETD7 JMJD1C THUMPD2 CHD2 MIA3 PCLAF TP53BP1 ATG14 FAM133B RHD RNF168 UBR4 CNOT2 SEC24A SAMD8 TBC1D15 SAP30BP GOLGA5 SLC5A6 MAP3K2 SFPQ RRBP1 DMTF1 PPIF BCLAF1 TFDP1 RBM38 PRPF4 LATS1 PRDX6 HSPA9 SDCBP SELENOH OGFRL1 HNMT METAP2 RTF1 ATXN2L ITSN2 DDX24 SKIL KBTBD2 N4BP3 GNA15 CSNK1E MIER3 NFIX STK17B NCR3LG1 ZDBF2 ICE1 ELF1 WDR20 OTULIN PDZD8 HIPK1 ZNF275 DNAJC4 OLFM2 KMT2E RALGAPA1 GON4L PDIK1L TENT4B IRGQ H2BC4 BEX3 COMMD5 H1-3 H1-4 ARID4B RBBP9 CRIPT PSMD12 MED21 KIF5B XRN2 RBM25 PRPF4B HNRNPH3 ATAD2B RELL1 KIAA0513 G2E3 HYLS1 SESTD1 FAM177A1 SMIM19 EXOSC6 PHF1 CNOT6L PSME4 P2RX1 CHD7 EAPP POFUT2 CFAP45 MTUS2 C5ORF24 STK19 CCDC59 ZNF773 FANCB PAFAH1B1 PKN2 SRSF10 ILF3 KANSL2 FAM122A DDX46 ISY1 LRRC41 DHX8 CBWD3 NCS1 MAP7D3 CIR1 ZFYVE16 ZC3H8 BRD7 POMT1 TCAF2 RSL1D1 ZBTB26 VIPR2 SLA2 R3HCC1 CRYBG1 ZNF644 RPRD1B PHF20 PCIF1 SPATA5L1 CACNB1 CCNJ RAB5IF ZNF331 H1-10 SLF1 IRAG2 KIR2DL4 NCBP2AS2 H4C5 H3-3B ANKDD1A H4C6 TAMALIN NAPG CDC40 Top 500 down genes for COVID-19 mild disease in human NK cells from GSE165461 Gene expression patterns of Natural Killer (NK) cells were compared between healthy human subjects and COVID-19 patients. CASP6 FAM8A1 NAALADL1 CTDSP1 EXOSC3 MOGS ACAD9 PF4 SLC22A18 NBR1 ACSL5 UBE2D1 SIGMAR1 DNASE1 SULT1B1 SLC27A4 NR3C2 IFITM2 CNDP2 RETSAT HSPBAP1 USP21 CD244 RAB10 DHTKD1 ADHFE1 CRADD FARS2 ACBD4 ARSG CISD1 ARHGAP18 ATPAF1 NDUFB6 LRRC61 PARP16 NAGLU NCOA5 LCP1 POU5F2 SSBP2 ATP10A IFFO1 TOMM40 TMEM273 MAPK8IP3 TRPV2 HS1BP3 VASP SPN PSD4 HK1 SLC38A10 NDUFB5 GLRX HVCN1 PSEN2 DERA SLC39A11 TEX2 DYNLL1 ESRP2 IKZF2 NCR3 ZNF600 PTCH1 RNF165 ZNF831 CXCR2 PDZD4 DRAXIN COLGALT2 ZNF266 CLDND2 STAR CYP4V2 BATF MAPT THEM6 BCAS3 SEMA4B CLSTN1 TMEM60 CTNNBIP1 CDK2AP2 DCK USP9Y MAP2K6 BTRC ZCWPW1 SYTL1 PLEKHG3 KLRD1 KLRC1 KNTC1 CD160 LPXN CX3CR1 RAC2 ARHGAP19 CENPH DNPH1 KIZ GNAL SAMD9L SPTSSA ACTG1 THRA CAPZB TXNIP RABL2A RPS4Y1 QDPR GIMAP8 MBNL1 EFNB1 CAMTA2 GIMAP4 TEX261 CDIPT ZNF692 PRPSAP1 VCL SSR3 UTY POU2F2 ASCL2 RGS14 NSG1 VAMP1 PTGER2 HIC1 RUNDC3B TESPA1 ZNF841 ZFP14 MRPL34 MPV17 GYS1 CHMP5 CHCHD4 GPKOW POLD2 GALNT7 COPS5 ARFIP1 PPP1R18 SDHAF2 EMG1 CTSO TBC1D19 ATG5 POP5 MRPL32 GLRX2 GEMIN5 PCSK5 YDJC ZNF512 MSANTD2 ZCCHC24 MAP1B PLCH2 B3GALT4 MTFR1L DPH2 PCYOX1L NIPSNAP3A BTBD6 NCR1 PRF1 TSPAN32 TRAF3IP3 TMEM229B HSCB BTBD2 BIN2 LMAN2L ZNF439 TMA16 N4BP2 SLC26A2 SLC35E3 MIS18A MED22 SPIN4 LRIF1 ZNF461 TMEM159 EIF2B4 BOP1 LIMA1 KLHDC2 NAPA ATP10D MVB12A ENO2 AMPD2 CD53 GNLY LTB PLEK MS4A1 ST6GAL1 HSPA1L RAD52 ITPRIPL1 RASSF4 SEMA7A SLC17A9 APBB1IP RNF144A LRFN1 TGFB3 ANGPT2 ITGA6 CCL3 IFNAR2 VPS45 STN1 OGG1 TUT1 CSTF3 CD300A FGR CLCN3 FAIM XBP1 SIM2 XPNPEP1 TNFAIP8 PPID HACE1 ZDHHC13 HPF1 CCDC92 CFAP298 ALAD AHNAK CMTM7 COMMD1 AARS1 ARMC6 MTG1 NIPA2 PTCD2 ZNF518B HERC4 COMTD1 JRK KCTD7 SYNE1 ZFYVE26 TMEM129 ZNF785 MFNG G6PD F8A1 PYCR2 CCM2 PDGFRB PRKY RSAD1 WBP1L ARAP3 FCRL3 KDM5D RPS6KA4 TRIP4 CPNE3 KLF8 TRMT1L GANC E2F3 CYTH2 MEN1 DTYMK PPAN PRR5 PRR5L SLC38A9 CMKLR1 MKNK1 CD1C DROSHA CPQ CXCR1 PGAM5 TMEM106B ZNF75D PIGB SLC35B3 GIMAP1 S1PR4 ADGRG5 TRIM35 PHKA2 PIGG GCLM S100B RFX3 PIDD1 MGMT CPSF2 RRP36 WDR92 GRK6 MGST3 SLC25A20 AHCYL1 TIMMDC1 RNASEH2C NAXD ZNF319 TTC39B MMAB JMJD8 NRM POLR3K VPS26B PXMP4 PUS10 GPSM2 MANEA C11ORF54 ZNF25 ZNF277 THAP6 GPD1L BTF3L4 CPSF1 SLF2 SNX25 STX2 PCNX4 ZSCAN29 PRR7 MAP4K2 DESI1 GOPC ZNF248 TBC1D32 SNAPC3 PAOX ZNF441 RIPOR2 PRAG1 DUSP23 MZT1 CSKMT STING1 VMA21 REXO2 C1RL SLC25A13 FGGY FCMR GIMAP6 ESYT1 CCDC127 HEATR5A RRNAD1 P2RX7 FMNL3 HDGFL2 LSM10 UBXN2B JAKMIP2 TRIM66 CARNMT1 KIAA0586 CENPB NABP2 BLOC1S3 PDE6D LRRC28 FASTKD1 OGFOD3 ANKRD26 C11ORF49 OCEL1 NHLRC2 SLC35B2 PKNOX1 ADGRL1 GTF2A1 IDH3A RASSF7 CLOCK ATP2B4 DDX3Y VAMP4 MYPOP TRIM27 SMIM14 E4F1 MEMO1 JPT2 LIX1L IPMK GPR22 COA5 ZC4H2 FCHO2 ZFY CROCC DCTN1 KRI1 SKAP2 CNTROB DPAGT1 TUBD1 TRIT1 DENND1A ACAD10 FAM189B FAM229A TOE1 UBE3D IFT27 PTCD1 TMEM216 HEMK1 ARHGAP33 TCEA2 INTS6L MCRIP2 CNR2 ZNF793 CRACR2A SETD6 HOXB3 TBC1D25 ABHD18 IFT52 DTX3 RCC1L CALHM2 LRRC8D PPP2R2B ERCC6L2 TYW1B MAML3 CCDC136 AFF3 ST3GAL3 GATD1 ETFBKMT SV2A LDAH BOD1 LDAH BOD1 ANKS3 RIC8B LRRC27 MOCS2 ENOX2 LDLRAP1 SLC24A1 C5ORF63 TMEM101 CHCHD5 TMEM250 KCNJ1 BCLAF3 MTMR2 SPINDOC STAMBP ABHD6 USP27X TTC13 PANK4 ZNF792 SLFN12 GFOD2 NSUN6 ZNF879 TATDN1 ERV3-1 HOXB2 TMEM266 METTL2A GCNA CARMIL3 GPATCH11 DGKK ASH2L C2ORF92 PWWP3A NLRP7 SERGEF SMIM8 DNAL4 SHISAL2A ZNF808 PRH1 EIPR1 ARL17B FLAD1 AL357556.3 EIF1AY Top 500 up genes for COVID-19 severe disease in human NK cells from GSE165461 Gene expression patterns of Natural Killer (NK) cells were compared between healthy human subjects and COVID-19 patients. RSRC2 UBE2D2 CD14 SUMO3 HSPA5 SEC14L1 STAT3 SQSTM1 NUP54 AKAP8 DDX21 UPF1 SLC7A7 UBXN1 ABL1 ZC3H18 RASA3 ING5 BRAF CENPF DYNC1H1 GRPEL1 NCL SRP54 FAR2 HSP90AA1 NFKB1 HMOX1 HLA-C HLA-A HGS EIF2AK2 FYN MGAM NPM1 BRD4 ELOB CXCL2 NUP98 SBNO1 ING3 NSD2 TGFB1 CSNK2A1 GOLGB1 USP7 MX1 CHD1 RCOR1 RAB5C RBM39 BTF3 BRF1 BAP1 RPS26 TENT5C NINJ1 RGS2 NR4A2 MT1E MTRNR2L12 MT-ND2 SLC2A1 RELT ATP1A1 PTGER4 RMDN3 STMN1 THBS1 HBEGF GRINA EMC10 EMILIN2 ZDHHC7 B3GNT7 LMNA URM1 SMAD7 DDB1 TOP2A P2RX4 EZH2 PLBD1 CTSB GTSE1 AREG SLC16A1 IFI44 ELL2 ASPM MAFG MAFB E2F1 MPDU1 MKI67 DTL RASGEF1B ABCB1 GSTM2 RUNX3 GATA3 KLF16 STAM HINT1 CDV3 PIK3IP1 SLC2A8 ZNF707 FOXO1 MED23 WHRN JAG2 SLC7A5 GMPS ATF3 GABARAPL1 MAP2K3 IRF4 HIF1A SAFB TFE3 BCL3 FCN1 EME2 MNT ULK1 ATG2A OAS3 KRT86 CHEK1 DBF4 CKAP2 HMGB2 CLEC7A COTL1 S100A9 CHAF1A HBB AAK1 VCAN SOCS3 TREM1 ADAR NAMPT NFIL3 C5AR1 TOX2 YBX1 SGK1 FMO1 PEBP1 NFKBIA COX7A2L BTG1 RPL10 ARPC2 LAPTM4A EPC2 SP3 DHX15 CDK16 ATF4 PIM3 FAM53B MXD4 CTU2 RBM3 PHLDA1 SAT1 NDUFV2 ZFP91 SUB1 YTHDC1 SUPT5H ATP2B1 NUCKS1 FAM160B2 METTL14 DYNC1LI2 BEX4 KDM6B DDIT3 SLA NR4A3 RORB S100A12 AURKC TNFAIP3 ZNF267 FUS PDE4A TP53INP2 SKI BRD1 IRS2 TAF1D ZNFX1 PFKFB3 SLC25A33 RRM1 CIB1 SRM SAR1A PTMA DCTN6 SF3B5 LDHB RLF MXD1 WBP11 ODC1 GPBP1 HSPD1 DUSP10 PDE4B SF3A3 SRSF2 NOP14 SETD2 IK HOXA5 SCAF8 DENND5A MCM6 RWDD4 REL S100A8 ZCCHC2 CREM PCGF5 MAP3K8 WDR90 SLC1A4 ERMN CDKN2C SLC43A2 PER1 SLC20A1 ZNF791 GMCL1 SMC3 SNRPA1 SMG1 METRNL RBMX GORAB TOP1 PRRC2C SECISBP2L CKAP4 PIK3R1 ST6GALNAC6 RELB PMAIP1 DUSP4 N4BP1 SMCHD1 RAB8B U2AF1 MMD FBXO7 EIF1 SARAF CASP8 PPTC7 PTPRE LPIN1 CCT6B CLK1 STK17A P2RX5 APOE HBA2 FCHSD1 CHN2 PDE1B IFNGR1 RAD21 POLR2C QRSL1 ACP1 RANBP2 UBE2B HBA1 DPP9 RNF11 TAX1BP1 NFKB2 SH3GLB1 COPA MAPKAPK2 GDE1 PSMC3 FAM32A RNF13 AKIRIN1 SNRNP27 TM9SF1 RNF115 SYAP1 IRAK3 GSTO2 ATG3 ASAH1 C9ORF78 CLCN7 CAPZA1 CLN3 ATP5F1A CIRBP CHMP3 GAB2 USP36 ZNF669 HELZ FAM118A EML4 NEMF ZC3H15 EIF3J PDIA3 ZNF326 DNAJC21 SNAPC1 PTPN2 RIOK1 PPP2R2A P4HTM POLR2A HNRNPC SMAP2 MADD ARHGEF7 RRP12 BRD9 LUZP1 MDC1 TTC7A TSPYL2 CTPS1 PLEKHM2 LRRFIP1 VPS37B SREK1 PHLDB3 WASHC5 AGFG1 SFT2D2 USF2 FAM3C CHD8 MRTFA JMJD1C SMC4 PIK3C2A MIA3 ATG13 ATG14 FAM133B GCNT7 RHD RNF168 UBR4 CNOT2 RFC1 SEC24A SHOC2 TBC1D15 STAM2 SAP30BP ZRANB1 SLC5A6 HSPA14 MAP3K2 SFPQ RRBP1 DMTF1 BCLAF1 TFDP1 RBM38 PNO1 RPP14 MRPL4 LATS1 TOPBP1 RPS4X PRDX6 HSPA9 RILPL2 SELENOH OGFRL1 RTRAF RTF1 ATXN2L WTAP ARID3B FAM168B MOK SKIL SYTL3 N4BP3 NFIX CPD KDM5B JMY ICE1 OTULIN RBM15 PDPR COMMD2 PDZD8 CCDC93 ZNF275 GPATCH8 KMT2E RALGAPA1 PPIL2 GON4L RBM5 GOLIM4 PHYH TENT4B IRGQ ZNF585A H1-2 H2BC4 COMMD5 EXOSC9 H1-4 ARID4B CCDC69 CRIPT MFSD14A PSMD12 XRN2 PRRC2A SAFB2 WDR26 FNBP1 HNRNPH3 ATAD2B PDLIM7 RELL1 C4ORF33 G2E3 CDC5L SESTD1 FAM177A1 SRRM1 EXOSC6 TCFL5 CNOT6L PSME4 CHD7 DDX51 ITPRID2 KLHL26 EAPP POFUT2 SLC35E1 CCDC59 SRSF10 CCZ1 OSBPL9 TEFM LRRC41 CCNK DHX8 NUDT13 KMT5C NMT2 CHST12 BRD7 POMT1 WIPF2 TCAF2 RSL1D1 VIPR2 SLA2 CRYBG1 MTMR1 HMGXB4 CACNB1 ZNF331 MCUB H1-10 SLF1 IRAG2 KIR2DL4 NCBP2AS2 H3-3B TAMALIN CDC40 CIAO3 H3C1 ZNF724 ARHGAP8 CENATAC CNOT9 DHRSX Top 500 down genes for COVID-19 severe disease in human NK cells from GSE165461 Gene expression patterns of Natural Killer (NK) cells were compared between healthy human subjects and COVID-19 patients. DCTPP1 PPBP UHRF1 NAALADL1 DDX58 LARP4B DPY19L1 ACAD9 SLC30A9 GABARAPL2 SIGMAR1 FYCO1 RBCK1 DNASE1 NR3C2 AASS B2M CNDP2 ALG8 RBM41 EXOSC2 AGTRAP LILRB1 DCAF7 DNAJC19 RAB10 CASP3 PCMTD2 FARS2 ARSG CISD1 GBE1 ARHGAP18 METTL7A ATPAF1 NDUFB6 NAGLU NCOA5 DCTN2 LCP1 MT-ND3 TMEM71 CDK2AP1 SPATA5 POU5F2 CCDC7 MT-ND5 SLC4A4 MT-CO1 SSBP2 MT-CYB MT-ATP6 MT-ND4 MT-CO2 NFIA TTC22 ATP10A SLC12A9 LAIR1 TRPV2 RPS6KA1 HDAC6 VASH1 SPN PLEKHO2 EHBP1L1 GLRX HVCN1 MYO1E MTCH2 DERA IL18 GSTO1 HEXB IDH1 DYNLL1 MICU1 ESRP2 IKZF2 KLRG1 CXCR2 PDZD4 COLGALT2 RAB11FIP5 CACNA2D2 ZNF266 MPEG1 CYP4V2 BATF THEM6 BCAS3 DNAJA3 MEF2C CTNNBIP1 CDK2AP2 DCK MAP2K6 TCF3 ZCWPW1 PLEKHG3 KLRD1 GRAP2 AOAH GIMAP7 KNTC1 LPXN CX3CR1 ARHGAP19 FAM78A FCHO1 CENPH LY9 SLFN12L NMRAL1 KIZ GNAL SPTSSA JUN NDUFA13 PSMB5 QDPR GIMAP8 LTBP3 GIMAP4 KLHDC3 TEX261 CDIPT ZNF692 CHCHD1 VCL OAT SSR3 PIN4 UTY KIFC3 ASCL2 RGS14 NSG1 VAMP1 TESPA1 ARHGAP25 ZFP14 SLC14A1 MAGEH1 FEM1B GGPS1 CMSS1 LAMTOR2 MPV17 GYS1 CHMP5 CHCHD4 M6PR GPKOW CRYZ ATP6V1D SLC25A11 LSM2 GALNT7 ARFIP1 PPP1R18 EMG1 SPIN1 ATG5 PNPT1 ABCB10 UBE2G1 GLRX2 DECR1 CCDC117 SLC25A46 MRPS6 MSANTD2 TRAPPC12 B3GALT4 MTFR1L DPH2 ANXA2R NCR1 PRF1 MAP2K1 TRAF3IP3 TMEM229B BIN2 ZNF439 DDX60 SUMF1 DCTD BBS2 SLC35E3 CCDC77 SPIN4 SCOC LRIF1 ADRB2 SYNJ2BP TMEM107 SIKE1 EIF2B4 XPOT METTL2B LIMA1 VAT1 LETMD1 CSTB ATP10D MVB12A CCR7 CD53 GNLY MS4A1 ST6GAL1 HSPA1L RAD52 ITPRIPL1 FLI1 RASSF4 ANGPT2 SIAH1 ITGA6 IFNAR2 STN1 OGG1 UBL4A UBE2V2 TUT1 RNF5 CSTF3 CD300A RGS19 EEA1 SIM2 FAM111A XPNPEP1 STARD3NL PLPBP TNFAIP8 OTUD1 CALCOCO2 HACE1 ZDHHC13 HPF1 WDPCP CFAP298 AHNAK COMMD1 MTG1 ZFP30 NIPA2 PTER NT5C2 HERC4 ZNF680 COMTD1 JRK KCTD7 SYNE1 TMEM129 MFNG RTN3 PSEN1 PYCR2 PPP1R13B PDGFRB PRKY GMPPA RSAD1 FAM214B ARAP3 FCRL3 GPR108 ROCK2 SLC5A3 CD320 TRMT1L GANC MEN1 DTYMK MTAP NME6 DPY19L3 NQO2 CAMK2G FIG4 PRR5 AP3S2 PRR5L SLC38A9 CMKLR1 MKNK1 ARSA DROSHA MT-ATP8 PGAM5 ZNF75D RSBN1L PIGB ZNF182 CD300LB NUMB GIMAP1 S1PR4 ADGRG5 TRIM35 TRIP11 PIGG AP5M1 GCLM RFX3 MRS2 MCM3 PPP2R3C MGMT CPSF2 RRP36 WDR92 RRS1 SH2D3C CRTAP RHOC MGST3 SLC25A20 PNKD PDSS2 KDELR2 CDKN2AIPNL MRPL30 PCNX2 ZNF319 TTC39B MMAB NRM AGFG2 POLR3K FEZ1 PXMP4 PUS10 FAM43A GPSM2 C11ORF54 ZNF25 THAP6 ZFP90 C1ORF159 SLF2 CREBZF KLHL42 ECI1 RFNG ARHGAP12 RSPRY1 DESI1 NOCT BRAP GOPC HIF1AN SOS1 FRA10AC1 PALLD FAM104B ARL4A ZNF441 RIPOR2 PRAG1 HIGD1A STING1 VMA21 FAM168A REXO2 PCCB FCMR GIMAP6 CCDC127 HEATR5A ST6GALNAC4 P2RX7 FMNL3 LSM10 DCAF12 NTPCR JAKMIP2 TRIM66 ZNF445 SLC4A8 CARNMT1 KIAA0586 ATP9B PDE6D MLH3 C11ORF49 MAP2K5 MTRF1L SLC35B2 INIP PKNOX1 ADGRL1 GTF2A1 TCEANC2 IDH3A RUFY2 SPECC1 VAMP4 ANKRD46 MYPOP SMIM14 CASK MEMO1 CLEC16A PPP1R21 RTL6 JPT2 LIX1L IPMK GPR22 C11ORF21 COA5 INKA2 ZDHHC21 CCDC39 SMARCAD1 CNTROB DPAGT1 CARNS1 TUBD1 POC5 GPD2 DTNBP1 DOK6 TRIT1 FAM189B FAM229A ACTR5 POLR2D METAP1 AGO3 LARS1 HEMK1 ARHGAP33 OSBPL3 ABHD18 RCC1L CSAD LRRC8D OARD1 ZNF440 ZNF354B MAML3 CCDC136 PYROXD2 GATD1 LDAH LDAH ANKS3 COQ8A CUTC ENOX2 IL12RB2 SLC24A1 C5ORF63 TMEM101 SAYSD1 CHCHD5 TMEM250 BCAS4 CARF TASOR BCLAF3 MTMR2 ZMAT1 STAMBP INTS9 PANK4 VPS37A USP40 ZNF792 GFOD2 TIGIT TTC16 TATDN1 RABL2B ERV3-1 TMEM266 MTIF3 METTL2A GCNA DGKK ASH2L PWWP3A NLRP7 SMIM8 DNAL4 ZNF808 EIPR1 SCYL3 FCSK MOSMO JRKL MTHFD2L SDR42E2 MTRES1 NPRL2 30 host factors of SARS-CoV-2 in HEK293T-hACE2 cells with MOI 0.01 from CRISPR screen of Grodzki et al. This genome-wide CRISPR screen involved infecting HEK293T-hACE2 cells cells with SARS-CoV-2 at multiplicity of infection (MOI) 0.01. The top-scoring genes across 3 experimental conditions are sourced from Figure 3(D). From Grodzki et al. (2021) Genome-scale CRISPR Screens Identify Host Factors that Promote Human Coronavirus Infection (bioRxiv, 6/04/2021). ALG5 TP53 BAX ARVCF EDC4 NPRL3 RPS4Y1 TMEM251 INTS6 XRN1 KBTBD6 SMCHD1 CDH2 ITFG2 TBC1D7 WASL SLC30A1 DNM2 C16ORF72 INTS12 C18ORF8 RFXAP CCZ1 FBXW10 URAD TMEM39A WDR35 GUCY2D ERICH6B DAZ3 31 host factors of SARS-CoV-2 in HEK293T-hACE2 cells with MOI 0.3 from CRISPR screen of Grodzki et al. This genome-wide CRISPR screen involved infecting HEK293T-hACE2 cells cells with SARS-CoV-2 at multiplicity of infection (MOI) 0.3. The top-scoring genes across 2 experimental conditions are sourced from Figure 3(G). From Grodzki et al. (2021) Genome-scale CRISPR Screens Identify Host Factors that Promote Human Coronavirus Infection (bioRxiv, 6/04/2021). CTSL ACE2 RAB7A PEX1 SLC12A9 GDI2 SLC39A1 VPS35 TMEM251 CTBP2 RNH1 CDH2 CCZ1B WDR81 PEX10 GNPTG F8A1 VAC14 CTNS STRADA MTMR9 MED13 C12ORF49 ARPC5L LUC7L2 EPT1 C18ORF8 SNX27 WDR91 CCZ1 GNPTAB Top 500 up genes for SARS-CoV-2 infection Day 2 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 NUP210 UHRF1 GIF HYOU1 PDCD1 UPF1 RNF24 CCND3 ACE2 PRRC2B FURIN TUBA8 CENPF A4GNT AQP2 QSOX2 TRIM25 NT5C DEDD IL22RA1 POLA2 OASL GNB1 SMARCA4 AGTRAP ISG15 NCAN CXCL9 SCARB1 MX1 STXBP2 KRT18 TSHZ2 PPP1R14C IL5RA TTC9 MUC15 CRYM MAP6 ANKRD33B CEP170 SYMPK TMBIM6 SLCO2B1 AQP3 LGALS3BP ZNF316 PRKCSH CD81 B3GNT7 KCNAB2 GANAB TYK2 CPVL NCSTN SRD5A1 FLVCR2 TICRR VSIG10L CLSPN TK1 GTSE1 AURKB LDLR PSEN2 DDIT4 STARD13 RNASE1 SLC1A3 KIFC1 HDLBP ABCD1 PADI2 BATF2 ANKLE1 MKI67 LIPA B3GAT1 BCL11B CEP126 CHI3L1 GATA3 DSCAM STK4 B4GALT3 AZIN2 CTSG JMJD6 EPN3 AGRN CGN WNT7B WWC1 SLC38A1 SLC7A1 WNT11 CLU SOX9 MMP8 CBLN4 MSX2 DCK SAFB SORL1 TAAR5 SLC45A4 IQCE RAB11FIP3 CBX4 HELZ2 ZNF710 LRCH4 LAT RSAD2 UBE2T IRF7 IL18BP IFIT1 TNIP3 CRMP1 NDC80 CCL17 IFIT3 IFIT1B C3 CH25H GINS1 DHX58 USP18 CMPK2 GDPD2 SNCA FABP7 HERC6 STAT2 PML JPH3 ADAR MUC5B LIPG RNF213 UBA7 GAL3ST4 LGALS12 SVOPL TMCC2 LY6E HMGCS1 IRF9 PSAP ATP6V0B ANK1 COL9A2 SLC25A25 ODF3 FLRT1 JAKMIP3 KBTBD8 RGR MYT1L FAM129C DMBX1 CALB2 TBC1D30 FOXO6 ALAS1 MSRB2 ATP6V0E2 HSP90B1 PSMD13 TTYH1 LAMB1 DYNLL2 KIAA0430 ARG2 ZFAND2A RANGAP1 CKAP5 ENC1 INSIG1 PGM1 HMGCR SQLE SRD5A2 GRAMD4 SUSD3 HS6ST3 ATP10B SOCS7 CELF3 ZCCHC2 PDK4 ZSWIM2 ANKFY1 TMEM229B PACSIN1 SPIB GRIK4 IFI6 BPIFB4 DDX60 TNFSF13B MX2 HERC5 MLEC PDPK1 WSB2 UCP2 LIPH RUNDC1 LPCAT1 FAM110C FAM179A CCDC142 ATP10D PACSIN2 PTGS1 CDA ITPRIPL1 JARID2 FADS2 PAPPA SRRM4 SLC39A12 KANK4 TUBB3 SDR9C7 CWH43 HPD REXO1 MAST1 MMD2 LCN1 ELFN1 CCL22 FSD1 SACM1L TNIP1 BCL2L14 AGO2 PARP1 HAUS8 SMURF1 CES3 ADTRP CSRP2 GAB2 LRRC20 OPA3 AGPAT3 REC8 SLC39A8 APC2 MLXIP LSS KLHDC7A SMPD3 FBXO10 CACNA1A PMM2 CRY2 STARD3 PLEKHM2 FDFT1 SFT2D2 PTPRJ MTHFR HSD17B3 ZBED4 ZNF81 MUC2 HCN4 E2F3 ATP2C2 A1BG CNTNAP2 TMEM211 SRGAP2 HSF1 PRKCG ATP13A2 NR1H3 NEIL2 GLS2 NUP50 GATA6 MAP3K9 DOCK8 MAPK4 PI4K2A NOX5 KIF9 CSRNP2 ADM2 SLC25A37 NRCAM HIVEP1 CSPG5 MPV17L KIF3C CEBPG CHST11 RAVER1 HCFC1 DISP2 VASH2 DIDO1 SLC26A9 PFKP AP3D1 RGMB DOCK5 DENND4A NUDT3 HOOK2 KLHL36 SAFB2 TCF20 EAF1 CDK5R1 LSM14B TVP23A CXADR TMEM120A EPT1 BCL7B STX1A DNAJB12 RAB11FIP4 PRKX ARID3A ASPHD2 MTUS2 GATAD2A PVRL2 DCTN1 DDX11 BSN MTMR4 KLHL25 PSPN CLIC6 TTLL6 TTC21A DENND1A GAP43 DLGAP3 RIMKLA DUSP18 CHADL CCDC157 STK35 BET1L CBLN3 TRIM44 FAM131C GCNT2 ATCAY MOCS1 MFSD9 ALPK2 NPFFR1 RAB3C ATP6V1B1 ADAMTS18 RASGRF1 KAZN CDH23 KNDC1 CUZD1 ELAVL3 SLC39A2 ELAVL3 SLC39A2 EFR3B CACNA1B SLC25A35 CRIP3 PRR29 CRAMP1L KCNE2 MAN2A2 TTBK1 CCDC40 TBC1D14 KIAA1467 PDIA2 UNC13A CAPNS2 LOC101685493 LOC101679667 LOC106006577 LOC101674886 LOC101674184 LOC101675569 LOC101672778 LOC106007463 LOC101683191 TMEM145 ANHX LOC106006594 LOC101680582 LOC101685857 LOC101675824 LOC101677667 LOC101682249 LOC106006068 LOC101692673 LOC101687732 LOC101693895 LOC101670560 LOC101679851 LOC101685684 BPIFB6 LOC101691795 LOC101684327 LOC101682547 LOC101683545 LOC101677928 LOC101677272 LOC106004887 LOC101676799 LOC101680596 LOC101689641 LOC101681639 LOC106005939 LOC101678204 LOC101685658 LOC101670342 LOC101679700 LOC101676466 LOC101679340 LOC101679526 LOC101681318 LOC101674231 LOC101671566 LOC101673985 LOC101672084 LOC101692021 LOC101687592 LOC101679842 LOC106006956 LOC101692249 LOC101690568 LOC106006036 LOC101684595 LOC101671862 LOC106003611 LOC106004119 LOC101691729 LOC101691570 LOC101685913 LOC106005704 LOC101671234 LOC101694619 LOC101692129 LOC106006955 LOC106003679 MYT1 LOC101682412 LOC101676120 LOC101692483 LOC101674695 LOC106006648 LOC106005541 GAREM LOC106003997 LOC101679940 LOC101672018 LOC101670959 LOC101674524 LOC101680342 LOC106003546 LOC101679471 LOC101679780 LOC106005160 LCN15 LOC106005247 LOC101683827 LOC101694624 LOC101684347 LOC101671787 LOC101679826 LOC101676601 LOC106005184 LOC101686300 LOC101673608 LOC101681321 LOC101693745 LOC101678319 LOC106006785 LOC106005523 LOC101674648 LOC101678316 SLC22A20 LOC101679648 LOC106004475 LOC101677113 LOC101677673 LOC101690201 LOC101677263 LOC101679332 Top 500 down genes for SARS-CoV-2 infection Day 2 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 IMPDH2 ENDOU NOX4 TMPRSS2 SLC25A21 EXOSC8 SAAL1 HOOK1 CRYL1 FBLN5 WRN FRMD6 MTMR11 PDILT VSTM4 PDE4D TMPRSS11D ITM2A MAP3K1 TOP2B NR3C1 LRRC40 RBM39 NAE1 NPHP3 SLITRK6 SDC1 KRT4 RPS11 HES1 RPL14 SLC40A1 TTC39A THRB RPL37 RPS8 LRIG3 FOXP2 PAX9 NCKAP1 CCDC80 SERPINB2 ZEB1 SLC16A7 POF1B UTRN INPP4B RPS13 RPL31 ZBTB20 RPS14 CFAP47 TMEM38A ARHGAP29 TMTC2 ITGA1 GRB10 CALCRL LGALS3 NETO2 BRCA2 MERTK JCHAIN RAPH1 NRIP1 ZNF365 PTGS2 LAMA2 ATR PKD2 B4GALT6 COL14A1 TFAP2A DSG3 SPARCL1 MEPE BNC2 KITLG ABI3BP SFRP2 MEF2A ELP4 GRID1 SMARCA1 RETNLB GP2 GEN1 KCNA6 KCNA1 MOGAT1 CNR1 NAV3 CPXM1 STON1 PDE2A ITGA8 DGKB RIMKLB IER2 FOS RASGRP3 DUSP1 JUN PDGFRA DCN RPL10 RPL26 FHL1 CCNL1 CDO1 GNG11 PHLDB2 CD36 VCL BPIFA3 ADAM32 PIK3R6 NTRK3 TBX3 CNKSR2 LIX1 SCARA5 DAPL1 HMCN1 LRRK2 COL21A1 PPAP2B ZFP37 ZNF292 GJA4 CCL28 ZSWIM6 FOSB PAN3 NPM3 TBC1D19 HSD17B2 DHX40 HMGN3 ITGB3BP RPL32 RPL34 PCSK5 PPAP2A MORC4 PLEKHH2 SLC38A6 ARGLU1 METTL25 COMP BLID TBL1XR1 RRAGB TTC21B PTPRD GLMN CEP192 VEGFC TMEM200A PLCB1 RASA1 CLEC3B HFM1 RPAP2 ACOT12 ADAMTS6 WISP2 CCDC15 ANKRD31 RP1 PRPF39 STPG2 PRPF38B THSD7A SYT16 RECQL CCDC28A N4BP2 ORC4 SLC35A1 GORAB ZRANB2 SPAG9 RRH DGKH SLC25A36 HPS5 OSR2 PLK2 KLHDC2 SRSF11 RPS6 KANSL1L CCDC178 SESN1 ADAMTS5 ZNF280D ZNF285 GNE DAPK2 SRSF12 ALX1 COL12A1 ENPP2 MMP2 GPR21 ADAMTS9 SCN2A ABCA12 RNF144A PRTG PRKG1 LPO RHOT1 COPS4 POT1 HBS1L ITIH4 KIT SOX5 TBX2 GNAQ POSTN MMP14 NEDD4 SQRDL ZMYM4 RYR3 SULF1 ZDHHC13 ARHGAP10 ZCCHC7 ZNF326 WDR75 CCAR1 PDE1A CCNT2 MIOS NEXN TENM1 PPP1R12A SREK1 GLS AMPD3 PRKD1 GHR ITIH3 PRKCE ZBED5 MPDZ FAM13C KDM6A TRIM24 GTF2A1L ADGRF2 JMJD1C RUNX1T1 TRIQK USH2A ARHGAP6 COL10A1 ATP2A3 SLC9A9 SENP6 TFPI ZNF449 UHRF1BP1L LTBP1 ZDHHC17 PPP2R5A ACSM5 LAMA4 SLCO1C1 FOLH1B CDK8 SFPQ ALDH1A2 CCNH ORC5 RPP30 RFWD2 ETFDH PXDNL KRT23 PALMD NAALADL2 SLC4A7 ZC3H10 ZNF280C BICD1 DLC1 CLK4 UBE2E3 ZG16B TENM3 ANKRD50 RNPC3 FAT4 VGLL3 CEP44 CD109 ANKRD28 PDE3A STAG1 PHF20L1 SERTAD4 PAXBP1 BICC1 KLHL23 ADGRA3 RAB34 SNTA1 7-MAR PSPC1 EVI5 ZNF248 SOS2 PRRX1 SSPN TTC28 SYNPO2 SLIT2 NCMAP CEP85L COL2A1 HCFC2 NID2 STK32B LOC101686332 PCMTD1 PTPN20 CNTLN DNAJC12 DTWD1 PPIP5K2 RBM46 LGI1 CAMK1G GARNL3 DAB2 SESTD1 YBX2 ARHGAP42 RBM45 MCM8 SLC17A5 ESYT2 MRPL39 PDS5B SLC25A12 CCSER2 RHAG FYTTD1 IPO11 RDH10 LDB2 TNMD FCHO2 FAM76B HECTD2 SYCP2 SMARCAD1 ZNF518A TMEM161B FAM135A C2CD5 ADAMTS20 RAPGEF4 WASF3 MYO9A TARBP1 CDKL5 ANGPTL7 NBEAL1 MINA GPC6 FHL5 RBM26 ICE2 DPH6 MTFMT CRBN RIF1 DACT3 ARHGAP28 CCDC102B RHOJ PHF14 DCHS2 FSD1L NOV PDE8B ZNF521 SNCAIP ASPN C1QTNF7 TMEM25 ST6GALNAC3 ST6GALNAC3 ZCCHC11 FAM212A ISPD IGSF10 RAD51B LRCH3 COQ3 CARF KRIT1 ZNF644 GRIA3 DNASE2B FAM92A1 TTC13 DIAPH2 FNDC1 PNPLA1 LOC101671870 LOC101686598 LOC101690327 MOBP LOC101678849 LOC106005317 LOC101690776 LOC101680224 LOC101684550 SGCG LOC101683871 LOC101679775 LOC106005017 LOC101679005 LOC101679687 LOC106003850 LOC101677582 LOC101692719 LOC106005998 LOC101670239 LOC101675829 LOC101688643 LOC106005567 LOC101684891 LOC106005908 LOC101688609 LOC101683085 LOC106003350 LOC106005084 LOC106004978 LOC101676973 LOC101690049 LOC106006319 LOC101688650 LOC101672959 ERC2 LOC106004226 LOC101680986 LOC101671834 LOC101676573 LOC101693479 LOC101682519 LOC106006149 LOC101694240 KERA LOC101693131 LOC106003800 LOC106005566 LOC106003813 LOC106007462 LOC106005124 LOC101680076 LOC101682202 LOC106004722 LOC106005051 LOC106003306 LOC106006840 LOC101693963 LOC106007139 LOC106004806 LOC106006214 LOC101681618 LOC101680631 LOC106005686 LOC101677064 LOC101689916 LOC101692162 LOC106003319 LOC106005762 LOC101673309 LOC101680057 LOC101686429 LOC101684252 LOC106004811 LOC106006806 LOC106004738 LOC101675717 LOC101673703 LOC101672982 LOC101670684 LOC106006686 LOC101687630 LOC106005832 LOC106004684 LOC101679978 Top 500 up genes for SARS-CoV-2 infection Day 7 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 TICAM2 DCTPP1 UHRF1 HSPA5 VCAM1 UBD PDCD1 NUP62 DPEP1 CXCL10 CCND3 YWHAG TPM3 PFKL LYN RAB8A GPX1 CFP GRIPAP1 NUCB1 STAT1 TRIM25 ITGA4 OASL PHB MSN FERMT3 IL17RA CD244 ICAM3 SPI1 CXCL9 RAB5C GRB2 SEPHS2 MGAT1 ENO1 LCP1 SERPING1 CXCL6 IGSF6 SMPDL3A ISG20 AIF1 FTL SYMPK ARHGAP30 TMBIM6 ITGB2 PDIA6 TMC6 C1QC LGALS3BP SHC1 PRKCSH ACSS1 TOR3A PGD C1QA RPS6KA1 PTK2B LRRC25 EMILIN2 CD81 SPN DOK2 PSD4 SLC16A3 EDEM2 TBC1D10C HK1 ITGAM TKT PDIA4 SYNGR2 SLC11A1 SCAMP2 CCT5 AK2 FLVCR2 LMNB1 CEBPA CHST13 PSEN2 ADPRH FAM72A MSR1 ATP6V1F TMEM150B ZBTB32 SHMT1 CLEC1B CTSZ COMMD9 SCIMP EPSTI1 TRPM2 IL18 MYDGF CLTA HDLBP CEP55 BATF2 PTPRO ALDH4A1 CCR3 SH2D1B CHI3L1 MATK TCN1 SLC2A6 IL18RAP MANF MPEG1 STAT5A BATF CISH CTSG EPN3 WNT7B SCNN1A CAPN1 MYH14 IRF8 MAP2K3 NPEPL1 HELZ2 PHC2 SBNO2 MBOAT7 HCLS1 KLRD1 CD226 CD48 SASH3 IRF7 SELPLG RINL AOAH NLRC5 IL18BP DUSP2 SH2D1A TNFRSF9 TAP1 CD27 GPR84 CLEC5A IL2RB CD3D CX3CR1 CCDC88B ITGB7 SECTM1 CD72 CORO1A FAM78A SLAMF9 TNIP3 CCR5 PTPRC FYB LY86 VAV1 PREX1 TBX21 GZMK COTL1 NLRC3 KIAA0101 MYO1F CFD S100A9 CD86 SIGLEC1 APOL6 CCR1 DHX58 CD5L EVI2A IL2RA TIMELESS STAT2 PML NFKBIE PARP12 PIM1 NOD2 LIPG IL4I1 RNF213 GPR35 PPA1 UBE2L6 UBA7 CNN2 LY6E ACTG1 ICAM1 IRF9 PSMB9 CHCHD2 DRAM1 P4HB MDH2 LYZ PRDX5 ARPC2 C1QBP TAPBP ABRACL CD74 LYPLA2 TYROBP RAN CCT3 TALDO1 CRELD2 CALR HN1 ATP6V0B LIMD2 LAPTM5 IL2RG EHD1 LBH HCK THEMIS2 CSF2RA NCF4 EFHD2 MARCKSL1 RASSF5 SAMSN1 LST1 MAP4K1 RGS14 SLA TAGAP BPI FAM167A TRIM22 AKR1E2 S100A12 GPR182 IKZF1 CYTH4 ARHGAP25 TNFRSF14 NEURL3 DUSP5 UBE2S MRPL34 LAMTOR2 M6PR SEC61A1 HSP90B1 PFDN2 STIP1 DPP3 NHP2 SDHAF2 PCNA ZNF593 DYNLL2 MAD2L2 SDF2L1 NUDC RANGAP1 HNRNPA0 PGM1 TIFAB MUL1 GRAMD4 TAP2 SUSD3 PRF1 MB21D1 TIMD4 SELL FCRLA NCKAP1L WAS SNX20 BATF3 SLAMF6 RHOH KLHL6 CD38 BIN2 CXCL11 IFI6 DCPS ALYREF METRNL ASRGL1 IDH2 RNF19B LGALS9 TNFSF13B MX2 CKAP4 PSTPIP2 WSB2 LPCAT1 MTPN P2RY1 ARPC1B MOB3C FAS BLNK FAM65B ARPC4 PTPN6 CSF2RB SERPINB1 CCR7 CD53 CRLF3 PLEK EVI2B PAG1 P2RY8 ADORA2A NCF1 SLC13A5 IL21R SURF4 CLECL1 PILRA ADGRE1 SH3BP1 FGR STX11 NCF2 TRADD BCL2L14 YARS TNFRSF1B ERP29 GBA HAUS8 PDCD1LG2 BAK1 MOB3A CD82 ARPC5 MAPKAPK2 SAE1 STK10 CYTH1 TRAF2 CAPZA1 BST1 CDC42SE1 LTB4R XCR1 ORAI3 MID1IP1 KIAA1024 PGPEP1 PRADC1 MFSD12 DDX39A GMFG TFEC RGS18 JAK3 PMM2 TTC7A MOAP1 TIMM13 TXNDC11 SNAP29 PLIN3 SPCS3 PTPRJ ZBED4 KEAP1 CDC34 ARSB RAB32 CMKLR1 ATP13A2 HK2 SEMA4A TREML2 S1PR4 ACSS2 PPP1R9B NUP50 HNRNPAB CCDC137 DOCK2 NRROS RNASEK RILPL2 PI4K2A TUSC2 SLBP RMI2 SDHC MANEAL MAPKAPK3 GNA15 CNP NDUFS8 9-SEP PFKP AP3D1 RBM10 ST3GAL2 EMILIN1 PRKCB ARHGAP15 CARD9 LOC101673948 LOC101673770 ELOF1 TSPAN17 GTF2F1 ASPHD2 SSR1 ZGPAT SKAP2 KLHL25 CLIC6 SLC25A19 MOCS1 UBE2G2 2-MAR KNDC1 OSBPL2 CNNM4 B9D2 CCDC40 SLC35C2 POU2F3 PARP15 LOC101675569 LOC101672778 LOC101692673 LOC101693895 LOC101679851 LOC101676601 LOC101677263 LOC101677848 LOC101685033 LOC101670738 LOC101672891 LOC101674675 LOC101675687 LOC101672053 LOC101693321 LOC101688417 LOC101684101 LOC101686215 LOC101675277 LOC101694369 LOC101687773 LOC101676963 LOC101694281 LOC101686197 LOC101669898 LOC101689258 LOC101680253 LOC101669908 LOC101675098 LOC101672345 LOC101670985 1-MAR LOC101688502 LOC101672987 LOC101690736 LOC101681255 LOC101672794 SWSAP1 LOC101693544 LOC101671409 LOC101680223 LOC101692964 LOC101688940 LOC101672824 LOC101682832 LOC101687145 LOC101692293 LOC106003421 LOC101682491 ARL5C LOC101674688 LOC101679372 LOC101682024 LOC101691093 LOC101686692 LOC101678099 LOC101673105 LOC101679441 LOC101679769 LOC101677761 LOC106003381 Top 500 down genes for SARS-CoV-2 infection Day 7 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 CEP112 CUBN RNF133 PTBP2 ASAP2 DAAM1 CACNA1D XPNPEP2 ETV1 UGGT2 TTN MTMR11 NCKAP5 PDE4D CLCA1 MARK1 ADHFE1 VPS13B YARS2 RWDD3 RPS6KA5 NPHP3 NBEA SPATA5 POU5F2 TRPS1 RBPMS COBLL1 NFAT5 FOXP2 RNF152 FREM2 PAWR PLCB4 ZEB1 TET2 ADGRL2 INPP4B SSBP2 SORBS2 EYA4 ZBTB20 CFAP47 TTC14 TMTC2 STAC3 ITGA1 HGF BRCA2 NRG1 ANG PER3 CHIC1 LAMA2 COL14A1 BCAS3 BNC2 DDHD1 STIM2 PTHLH SCP2D1 MEF2A ELP4 SMARCA1 B3GALT5 GEN1 RYR2 NAV3 CCDC129 NEGR1 RIMKLB SLC3A1 PTPRB RAPGEF2 NPNT OGN ADAMTS15 LUC7L3 CCNL1 TCF4 PHLDB2 TNNI2 PTGER3 NTRK3 NLGN1 P4HA3 PRR16 HMCN1 TCERG1 ADAMTS3 IL23A PPAP2B ZNF292 IMPG2 KIAA0408 ADRA2A SEC31B SLC25A27 ZSWIM6 STK39 TBC1D19 MAP4K3 SEC24B PCSK5 PLEKHH2 RSRP1 OGT ARGLU1 MSANTD2 METTL25 BLID TTC21B MAP2 CEP192 TMEM200A FANCG PLCB1 RASA1 PSD3 HFM1 ACOT12 PKD2L1 ADAMTS6 PRPF39 FNBP4 STPG2 THSD7A ARID4A ORC4 GORAB ZRANB2 RRH XRCC4 PNISR THOC2 DGKH SLC25A36 ZNF426 PLSCR4 DYSF SF3B1 SRSF5 KANSL1L CDON ADAMTS5 ZNF280D HUS1B EID3 GREM2 RNF148 SRSF12 ALX1 LSMEM2 GPR21 SCN2A CSMD2 TECTA GPR52 CCSER1 RMDN1 HBS1L MDM4 SOX5 RECK HDAC8 ZMYM4 RYR3 ZNF569 HELZ USP53 ZNF326 FILIP1 CCNT2 ZMYM2 NEXN TENM1 EPC1 SREK1 GLS PRKD1 SYDE2 ZBED5 PER2 MPDZ LCORL KDM6A PARD3 LPP GTF2A1L CRISPLD1 JMJD1C TTC6 CTTNBP2 RUNX1T1 SETD5 TRA2A SLC9A9 EPG5 PRKDC ZCCHC4 ZDHHC17 PARP4 LAMA4 RFX3 SLCO1C1 CDK8 SFPQ DMTF1 ALDH1A2 TIAL1 CNOT4 ZNF407 GGNBP2 MLLT10 BICD1 CLK4 RNPC3 CEP120 TRPC1 CAPRIN2 ANKRD28 JMY PDE3A PAXBP1 KLHL23 7-MAR RALGAPA1 BAZ2B MYOM1 FBXO38 PSPC1 PIAS2 BRWD1 GJC1 CDK14 PRRX1 CFAP54 MGAM2 CCDC171 SSPN PHKA1 SYNPO2 RUFY4 RBM25 PRPF4B ZFC3H1 CEP85L CHD9 TYW5 DOCK4 B3GALT2 LOC101676428 RPS6KA6 PPIP5K2 CAMK1G GARNL3 MRVI1 SESTD1 GAB1 ARHGAP42 RBM45 NKTR SCAPER ESYT2 BRWD3 ST7 CCSER2 MBTD1 CSPP1 LDB2 MSS51 ULK4 RPRD1A FCHO2 FAM76B SCML1 HECTD2 GCFC2 SYCP2 ZNF518A TMEM161B ATL2 FAM135A FER FIGN C2CD5 ZNF385D ADAMTS20 RAPGEF4 RAPGEF5 MYO9A TARBP1 CDKL5 GPC6 GRM2 CPSF6 FHL5 LUC7L YY2 TRMT44 DDX46 DPH6 AGO3 MTFMT RANBP17 TRIM33 RIF1 ZNF300 RHOJ PHF14 LARP1B DCHS2 CACHD1 ALG13 LEKR1 FREM1 LRCH2 WNK3 ZNF521 SNCAIP BBS9 VTI1A CDKAL1 F8 RAD51B LRCH3 COQ3 CARF ADGRG2 POLK DDX26B KRIT1 ZNF644 ZMAT1 PLAG1 AHI1 DIAPH2 ZNF10 NDUFAF5 KIAA0825 DPP6 ZNF331 RPA4 KIF16B FNDC1 LRRC7 LOC101690327 MOBP LOC106005317 LOC101690776 LOC101684550 LOC101679775 LOC106005017 LOC106003850 LOC101677582 LOC101692719 LOC106005567 LOC106003350 LOC106004978 ERC2 LOC101671834 KERA LOC106003800 LOC106005566 LOC106003813 LOC106007462 LOC101682202 LOC106005051 LOC106007139 LOC101680631 LOC101692162 LOC106005762 LOC101680057 LOC101686429 LOC106004738 LOC101675717 LOC101673703 LOC101672982 LOC101670684 LOC106006686 LOC106005832 LOC101689723 LOC101689121 LOC101686871 LOC101679616 LOC106005784 LOC106003712 LOC106006210 LOC106006843 LOC101673108 LOC106007154 LOC106004539 LOC101688938 LOC106004036 LOC101677601 LOC101684740 LOC101691605 LOC101685331 LOC106004647 ARHGEF33 LOC106003548 NMS LOC101687369 LOC106006924 LOC101673336 LOC101693026 LOC101686272 LOC106006227 LOC106003353 LOC106004710 LOC101687626 LOC106005637 LOC106006873 LOC101689141 LOC106003877 LOC106006263 LOC106005549 LOC106003433 LOC106003788 LOC106004155 LOC101678282 LOC101689178 LOC106004537 LOC106005554 LOC101679208 LOC101693690 LOC101683630 LOC101672536 ZNF660 LOC101688539 LOC101672202 LOC101686140 LOC101677211 PURG LOC101674253 LOC101682383 LOC106007196 LOC101674458 LOC101676112 LOC106006120 LOC106005041 LOC101681919 LOC101691401 LOC106003814 LOC106005448 LOC101677642 LOC101692727 ATRNL1 LOC106005132 LOC101686105 RTTN LOC101680791 LOC106004689 LOC106003946 LOC106003721 LOC101677143 LOC106006138 LOC106003730 LOC101681826 LOC101688785 LOC101685008 LOC106004784 LOC101691437 LOC101693739 LOC101676209 LOC101673601 LOC106003597 LOC106006314 LOC101684148 LOC106005591 TFAP2C LOC101676727 CNTNAP4 LOC106006942 LOC101686198 LOC101680184 LOC101670772 LOC101687971 LOC106005312 LOC101681193 LOC101677498 LOC106005545 LOC106005394 LOC101687351 LOC101680623 LOC101684616 LOC106006453 LOC106005583 LOC106007338 TDRD15 LOC101673848 LOC106005647 LOC101690273 LOC101693847 LOC101686003 LOC106005584 LOC101683060 LOC106006347 LOC101673182 LOC101688007 Top 500 up genes for SARS-CoV-2 infection Day 14 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 NUP210 AMACR ERMP1 UHRF1 HSPA5 HYOU1 PTPN3 SLC27A2 SLC1A1 YWHAG VIL1 PRR15L ACSL5 NF2 BAG3 PITRM1 AQP2 CALM1 QSOX2 ATP1B1 ANKRD66 HSPA8 ARF6 NCAN SCN3B ENTPD5 NEU1 UNC119B ELL3 DEDD2 PCLO ARL3 SIX1 STK33 PARD6B HOPX SOX2 MAP6 GCNT4 MAP7 C2CD2L AQP3 GANAB ABHD2 SCAMP2 NEK2 PSEN2 ANXA5 CLTA ACVR1B HDLBP TEX2 DYNLL1 SORT1 B4GALNT3 B3GAT1 CEP126 GDF11 CDHR3 CDHR1 BCAN PTCHD1 DMRT3 EPN3 CGN DSP SCNN1A WWC1 MYH14 ZNF217 DMRTA1 SOX9 WNT16 CNGB1 IRF4 SAFB CCDC170 SORL1 SYNPR SLC24A2 CBX4 CCNA1 CYFIP2 LCK CRMP1 COCH SNCA GNAL JPH3 HCN1 PPP2R2C SCN3A CD59 FAM73B CLIC5 FBXO16 HSPH1 ATP6V0B DNAJA1 CELF4 AMER2 SYP ODF3 SYNGAP1 AKR1E2 FLRT1 KBTBD8 BRINP2 MYT1L NACAD TMEM178B DMBX1 FBXL16 RGS9BP TP53INP2 FOXO6 HSP90B1 CKB PSME3 STIP1 SUSD5 AHSA1 DYNLL2 LDHB MXI1 CHST6 DNAJA4 NUDC FKBP4 RANGAP1 CKAP5 ENC1 PIK3C2B KRBA2 NARF REEP1 UHMK1 DHRS13 LINGO1 MKKS GRAMD4 RNFT2 HS6ST3 CELF3 RIIAD1 LRRC23 ZMYND10 WDR31 TNFAIP8L1 PACSIN1 SLC1A4 TUSC5 RTN4RL1 LRGUK GRIK4 ZMYND12 RP2 SEC14L5 MBNL3 MLEC CHD4 NOL9 PDPK1 KPNA6 PAQR8 CCDC173 FAM110C BBS4 LINGO2 ATP10D SARAF ST6GAL1 THAP2 SEC14L2 APBA1 CADM3 KANK4 NR2E1 HPD NPTX2 KIF5A SV2C S100A5 MAST1 FSD1 TERF2IP TRAPPC4 UCHL1 FOXJ1 COPG2 MOB3A COQ2 STXBP5L ACBD7 ALKBH5 LPCAT4 ERCC4 LRRC20 KCNJ2 KCNC4 CCDC17 FBXO10 RHOBTB2 PIM2 CCDC114 DNAAF1 PMM2 GGA2 MOAP1 HIPK2 FAM219B TMEM30B SNAP29 SFT2D2 STMND1 ZBED4 SOWAHA MUC2 LRRN1 GANC DGKI GOLM1 MAGI1 OTOA HOMER2 SYT7 GCNT1 TIGD4 ULK2 LRRC59 GCNT7 NCAM1 DNAH9 IMPDH1 HSD17B13 APBA2 NEIL2 GLS2 NUP50 GTF3C5 HNRNPAB CCDC137 RAG1 MAP3K9 KIF9 TUSC2 TMOD1 AK1 BICD2 L1CAM ADM2 MANEAL MPV17L KIF3C VSNL1 MAP7D2 ENDOD1 ADAM23 KIF5C CEBPG ANK2 DISP2 ZBTB40 PFKP AP3D1 SUGP2 RGMB TCHP SYT11 KLHL36 CFAP57 ODF2 PDE1C MGST2 HDAC11 EAF1 TDRKH OTUD3 LSM14B PCDH19 KIAA0513 TRIM66 PDE6D WDR60 PKNOX1 TMEM170A KIF24 PRKX SMIM11 PANK2 ARID3A SMYD1 COLQ DCTN1 SGTB GPRIN1 ADCY3 KIAA1644 PEX26 MTMR4 CLIC6 TTLL6 CLSTN2 GABBR2 DCX TMOD2 TTC21A SPATA6L AMIGO1 KCNA2 FOXN4 SHROOM2 TENM4 LRRC74B WDR66 TMEM216 ST8SIA1 CDHR4 CDH7 PAK3 TRIM44 ATCAY CDRT4 ACVR2B SMIM4 NKIRAS1 AK7 NOL4L ZFYVE19 MFSD9 TMC7 SH3GL2 CPEB1 ATP6V1B1 TMTC4 DNAJC28 TMEM200C RAB6B RGS9 KNDC1 TMEM74B ELAVL3 ELAVL3 EFR3B RD3 CNNM4 CACNA1B WIPF3 KCNE2 UBE3C MAN2A2 RIC3 KCNJ1 VWA3A INSM1 CCDC40 PNMA1 TMEM180 CENPBD1 KCNK12 ZC2HC1C CCDC151 PTPDC1 MTMR7 DNAI2 KIAA1467 SCG3 TEX33 RTP1 CCDC108 EBF3 UNC13A RABL2B DNAI1 LRRC48 FAM162B DGKK LOC101674886 LOC106007463 LOC101675824 LOC101677667 LOC101692673 LOC101693895 LOC101682547 LOC101683545 LOC101681639 LOC106005939 LOC101670342 LOC101673985 LOC101679842 LOC101692249 LOC101684595 LOC106004119 MYT1 LOC101682412 LOC101676120 LOC101692483 LOC106006648 LOC101670959 LOC106005247 LOC101683827 LOC106005523 LOC101679648 LOC106003729 LOC106006083 DRC7 DPF3 LOC106004612 LOC101674498 LOC101678571 LOC101685220 LOC101676649 LOC101691334 LOC106007215 LOC101691431 LOC101680002 LOC106007469 LOC101670884 LOC106006957 LOC101677815 LOC101674161 LOC101694623 LOC101675296 LOC101690636 TCTE1 LOC101686969 LOC101690991 TMEM218 LOC101681077 LOC101678057 LOC106004558 LOC101688808 LOC101680276 LOC101689416 LOC101676702 LOC101690749 LOC101685412 LOC101678842 LOC101681359 LOC106005217 LOC101669926 4-MAR LOC101692034 LOC101679887 LOC101683929 LOC101679385 LOC106007425 LOC101692935 LOC101681536 LOC101687828 LOC106006651 LOC101673799 ZSWIM5 LOC106004158 LOC101677887 LOC101691709 LOC101689437 LOC106003956 LOC101676039 LOC101678226 LOC101689691 LOC101692890 LOC101677652 LOC101691116 LOC101680256 TSHR LOC106006512 LOC101671931 LOC106003309 LOC101670515 LOC106007332 LOC101694319 TBATA LOC101693577 LOC101676478 LOC101682808 LOC106005471 LOC101689356 LOC106004167 LOC101692737 LOC101687253 LOC101679170 LOC101678547 LOC101680608 LOC101686861 LOC101689447 LOC106005557 LOC106004205 LOC101686541 LOC101693397 LOC106004619 LOC101692265 LOC101670152 LOC106005536 LOC101685469 SLC1A2 LOC101686093 LOC106006709 LOC101687856 LOC106004541 LOC101691089 Top 500 down genes for SARS-CoV-2 infection Day 14 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 CUBN RNF133 TCF12 CD34 SLC25A21 PTBP2 SAAL1 DAAM1 ENPEP MTMR11 PDE4D FBN1 MYCBP2 FBN2 TLN2 USP15 LRRC40 VPS13B YARS2 PLEKHO1 NPHP3 SPATA5 POU5F2 TRPS1 THRB NFAT5 SMPDL3A PAX9 CCDC80 ZEB1 TET2 UTRN SORBS2 ZBTB20 THBS1 HBEGF GAS2L3 TMTC2 ORC1 RGS16 BRCA2 MERTK DTL ZNF365 CHIC1 PTGS2 LAMA2 ATR RUNX2 KLF10 B4GALT6 COL14A1 TFAP2A BCAS3 MST1R MEF2C BNC2 LEF1 PAX3 WNT9B DDHD1 ASIP WWOX PTHLH MEF2A ELP4 HACD1 RGS1 GEN1 KCNA6 SELE COL24A1 GRIA1 NAV3 STON1 VCAN BTBD16 GFPT2 PLAU RIMKLB SLC3A1 IGFBP4 SNRK GRASP EGFL7 RAPGEF2 SEMA3C RBMS1 S100A4 DCN ADAMTS15 BCL6B ESAM CCNL1 IGFBP7 TCF4 PHLDB2 NRP1 VCL GEM PTGER3 AQP6 PI15 STARD9 TGFB1I1 CNKSR2 NLGN1 SCARA5 PENK LHX6 PRR16 HMCN1 TCERG1 LONRF3 LRRK2 HDAC9 ADAMTS3 EDNRA PPAP2B ZNF292 CPXM2 GJA4 KIAA0408 SLC25A27 AMOTL2 KLHL15 ZSWIM6 ALKBH3 KCTD9 SEC24B PCSK5 VAV3 PLEKHH2 PDE4B SLC38A6 ARGLU1 MSANTD2 METTL25 EFNA1 COMP BLID CREBRF TTC21B MAP2 PTPRD GLMN CEP192 COL11A1 VEGFC CDH6 PLCB1 CHSY3 IL34 RASA1 CLEC3B HFM1 ACOT12 NDST3 ADAMTS6 USP25 RASL11A NID1 PRPF39 FNBP4 STPG2 THSD7A RECQL N4BP2 XRN1 ORC4 TRANK1 ZRANB2 PIK3R1 RRH XRCC4 PNISR THOC2 DGKH SLC25A36 OSR2 PLK2 CDK17 PARP8 DYSF SF3B1 SRSF11 SRSF5 CD44 KANSL1L ADAMTS5 ZNF280D BACH2 HUS1B GREM2 RNF148 SRSF12 ALX1 NR1D1 SCN2A TRPM3 RNF144A GPR52 CCSER1 HBS1L ITIH4 OLFML1 MDM4 SOX5 HDAC8 NEDD4 RYR3 MCM9 RIN2 DCAF4 HELZ THBS3 REV1 ZCCHC7 USP53 ZNF326 PDE1A PTPN2 CCNT2 TENM1 EPC1 ELK3 SREK1 GLS AMPD3 PRKD1 LRP2 SYDE2 ZBED5 MPDZ MAGI2 TDRD6 LPP GTF2A1L CRISPLD1 JMJD1C TTC6 SLC2A12 RUNX1T1 SETD5 ARHGAP6 COL10A1 SLC9A9 EPG5 PRKDC KCNJ8 RC3H1 USP45 ALDH1L1 LTBP1 SAMD8 ZDHHC17 PARP4 LAMA4 CDK8 SFPQ WSB1 CBLB TTI2 GTF2H1 COL16A1 TIAL1 SLC41A3 PEG10 SCAF4 LYST ZNF280C ZNF407 TIAM2 GGNBP2 MLLT10 MED13L DLC1 CLK4 COL8A1 MYSM1 REV3L RNPC3 FAT4 CD109 ECM2 QPCT CAPRIN2 ANKRD28 PDE3A RFC3 STAG1 PAXBP1 KLHL23 RBM15 7-MAR RALGAPA1 BAZ2B PSPC1 ZNF248 PIAS2 RAPGEF6 GJC1 PRRX1 DOCK7 PHKA1 TTC28 SYNPO2 EIF5 ZFC3H1 CHIC2 CEP85L IKZF5 TYW5 NID2 SFMBT2 CNTLN RPS6KA6 PPIP5K2 FMOD GARNL3 MRVI1 SESTD1 ARHGAP42 RBM45 NKTR MCM8 SENP5 BRWD3 SLC25A12 ST7 CCSER2 APOLD1 GNG4 MSS51 FCHO2 FAM76B SCML1 HECTD2 SYCP2 ZNF518A TMEM161B CPNE8 FER C2CD5 ELMO1 RAPGEF4 WASF3 MYO9A TARBP1 PIEZO2 PCNX ANGPTL7 NBEAL1 SYT15 CPSF6 THBS4 RIC1 TRMT44 DPH6 DDX52 CCDC141 RANBP17 RIF1 ARHGAP28 ZNF300 CCDC102B RHOJ PHF14 PCDH18 DCHS2 ALG13 FREM1 SNED1 SNCAIP FAM212B VTI1A RAD51B ADGRV1 LRCH3 COQ3 CARF ADAMTS12 DDX26B KRIT1 ZNF644 ZMAT1 LDLRAD4 TDRD3 PLAG1 PPT2 DIAPH2 NDUFAF5 HSF5 DPP6 RPA4 GJD4 LOC106005317 LOC101690776 LOC101684550 SGCG LOC101679775 LOC106005017 LOC101679005 LOC106003850 LOC101677582 LOC101692719 LOC106005567 LOC106005908 LOC101683085 LOC106004978 ERC2 LOC101680986 LOC101671834 KERA LOC101693131 LOC106003800 LOC106005566 LOC101682202 LOC106003306 LOC106007139 LOC101681618 LOC106003319 LOC106005762 LOC101680057 LOC101686429 LOC106004738 LOC101672982 LOC101670684 LOC101689723 LOC106007154 LOC106004539 LOC106004036 LOC101691605 LOC101693026 LOC101686272 LOC106004710 LOC101687626 LOC101689141 LOC106004537 LOC106005554 LOC101679208 LOC101693690 LOC101672536 LOC101686140 PURG LOC101682383 LOC101674458 LOC101676112 LOC106005041 LOC101681919 LOC101677642 LOC101692727 ATRNL1 LOC106005132 LOC106004689 LOC101677143 LOC101688785 LOC101685008 LOC106003597 LOC101684148 CNTNAP4 LOC106006942 LOC101686198 LOC101680184 LOC106005545 LOC101680623 LOC106006453 LOC106005583 TDRD15 LOC101690273 LOC101683060 LOC101673182 LOC106005015 LOC106006371 LOC101686287 LOC101694604 LOC101672066 LOC101686302 LOC101677709 LOC106006602 LOC106003323 LOC106003553 LOC101673617 OTOGL LOC101679698 LOC106006682 LOC101682876 LOC101689705 LOC101692993 LOC101691312 LOC106005444 LOC101673805 LOC106005050 LOC106004179 LOC106004935 LOC106004536 LOC106006006 LOC101687368 LOC106003583 LOC101673739 Top 500 up genes for SARS-CoV-2 infection Day 21 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 AMACR DCTPP1 SPTB DCAKD ERMP1 UHRF1 HSPA5 ATP6AP1 ERGIC1 CISD3 PTPN3 SLC27A2 SLC9A3R1 BAIAP2L1 PPP1R14D YWHAG GPT SLC22A18 PRR15L SCCPDH YWHAE ACSL5 NF2 GRPEL1 RNF41 MPZL1 CALM1 SPTBN2 ATP1B1 TUBA4A MGAT4B NT5C RETSAT G3BP1 PI4KB SMARCA4 AGTRAP NAT14 HBM PIGU BAG5 ESM1 SEPHS2 SLC25A39 SMYD4 TSR2 COQ10A TMED4 DOLPP1 GAL3ST2 METTL7A FN3K TBCB PCP4L1 KRT18 STOX1 ARL3 SIX1 STK33 AQP5 MAP3K19 NDUFB2 SOX2 MAP6 ATOX1 CFAP53 MAP7 SYMPK ATP1A1 BANF1 PRPS1 AQP3 GLYR1 NUMA1 ZC3H7B SRSF9 GANAB HK1 ABCC3 DDB1 SCAMP2 DHCR24 MRPL37 VSIG10L HSD17B4 NEK2 PSEN2 JPH4 CLCN4 DDIT4 ANXA5 FADS1 ROGDI CLTA ACVR1B HDLBP TEX2 DYNLL1 SCD TSPYL1 RMND5A MARS ABCC4 ABCF2 DMRT1 DMRT3 SPINT2 EHHADH EPN3 CGN AP1M2 SCNN1A WWC1 DNAJA3 FAM83G TPD52L1 DMRTA1 CLU WNT16 SAFB CMTM8 TMEM164 IQCE CCNA1 LCK CX3CR1 PON1 ALAS2 RAMP1 RHCG TSPAN13 FAM73B AKR1A1 HMGN1 HMGCS1 FBXO16 SLC16A11 ACAT2 ZBTB16 HSPH1 NDUFV3 ATP6V0B FAM107A DNAJA1 SELENBP1 GLRX5 GLOD4 BEX4 PGRMC1 AKR1E2 SAMD15 TMEM150C SLC14A1 RGS9BP TP53INP2 FAM161B FOXO3 MSRB2 SEC61A1 CKB PSME3 STIP1 AHCY WDR54 MRPS30 FGF13 ST13 DYNLL2 PFKM BBS5 ZFAND2A KHDRBS3 NUDC FKBP4 GOT2 MKRN1 RANGAP1 HNRNPA0 HSD17B7 KRBA2 TACR3 CCDC64B PGM1 SQLE ZCCHC12 SRD5A2 FAM134C FEN1 STK32C NRAP RIIAD1 CLDN8 FAM92B WDR31 CDC42BPG RNF182 AARS MMACHC C6 DCPS ABAT SUMF1 FAM149A BBS2 CIPC MLEC CEP104 NOL9 KPNA6 CLUAP1 TCTA TTC8 BBS4 FAM210B BRI3BP SARAF FADS2 PRPH SDR9C7 TMEM214 GNA12 TERF2IP TRAPPC1 TRAPPC4 YARS ARRB1 SETD3 SPG21 RAB22A PSMC5 COQ2 GID8 PEX19 RDH16 CCDC92 AIG1 BECN1 ALKBH5 MID1IP1 ERCC4 SPINK4 OPA3 AGPAT3 LRRC49 ACTR1B KIAA1024 PINK1 ATP9A KLHDC7A FBXO10 PMM2 MOAP1 FBXO31 LETM1 TXNDC11 FAM219B ATP6V1G2 TMEM30B SFT2D2 ZBED4 SOWAHA SIRT3 ECE1 GOLM1 STEAP2 LRTOMT ZNF664 FANK1 TIGD4 STPG1 ULK2 LRRC59 IVD KCNA5 FANCF TREML2 PCYT1B AP3M2 FNTB MRS2 MTFP1 VPS4A CCNG1 BIRC7 NUP50 THAP4 GTF3C5 CCDC137 PRDX6 PI4K2A KIF9 TUSC2 ECHS1 MAPK8IP1 TIMM17A AK1 SRPRB TTPAL MANEAL PXMP2 GALNT10 STRBP CCDC121 SSX2IP KLHL13 ZNF579 TECR INTS5 EMB FAM217B ASMTL KIAA1191 ECH1 AP3D1 FAM20B TCHP MRPS14 ARL14EPL NUDT3 ARSD HOOK2 SHANK2 POMK ODF2 PAIP2B MGST2 HDAC11 BPHL PKN1 MED9 OTUD3 DCDC2 EML1 LSM14B DUSP14 MRPL19 ASCC2 RAB3IP IFT140 KIF24 B3GALT6 RAB11FIP4 UROS MRPS28 FAM46C SMIM11 HEMGN SDHAF1 TCTN2 TMEM185A ASPHD2 SMYD1 PPP1R26 DCTN1 CDKL2 PEX26 JAGN1 SPEF1 CLIC6 MRPL38 AMIGO1 CCBL1 SHROOM2 INPP5J DUSP18 SEC14L3 ARV1 LRRC74B COG4 CCDC157 PPP1R32 WDR66 RBM15B E2F5 NPHP4 ZNF689 DNAJC5 LRRC73 SPIRE2 SMIM4 DNAJC14 MOCS1 AK7 ZFYVE19 MFSD9 LRRC46 TMC7 RAB19 AGBL5 SH3GL2 MFSD4 ATP6V1B1 TMTC4 DNAJC28 KAZN CDK20 KNDC1 CNNM4 PRR29 RAB28 ANKRD24 UBE3C TTLL9 CCDC40 MORN3 TBC1D14 VRK3 ABHD6 PNMA1 AHSP NEK4 GAS8 ACYP1 CNIH2 RABL2B LOC106007463 LOC101683191 LOC101692673 LOC101693895 LOC101691795 LOC101683545 LOC101689641 LOC101672084 LOC106004119 LOC106005704 LOC106006648 LOC101686300 LOC101681321 LOC101669898 LOC101679441 LOC101679769 LOC106003729 LOC101674498 LOC101676649 LOC101677815 TCTE1 LOC101688808 LOC101680276 LOC101690749 LOC101673799 LOC106004158 LOC101677887 LOC101676039 LOC106006512 LOC106007332 TBATA LOC101692737 LOC101686861 LOC106006709 LOC101691089 LOC101672711 LOC106004254 LOC101677466 LOC101692227 MEF2BNB LOC106005941 MYCBPAP LOC101692170 LOC106005571 LOC101685103 LOC101671852 MPL LOC101687216 LOC101679966 LOC106006570 LOC101684052 LOC101678900 LOC101693326 OSCP1 LOC101680365 LOC101678705 LOC101671818 LOC101681864 LOC101685067 LOC101683725 LOC106004999 LOC101690118 LOC106006702 LOC101687953 LOC101692996 LOC101692735 LOC101670304 LOC101673656 LOC106004433 LOC101675948 LOC101676905 LOC101671415 LOC101680285 LOC101682710 DMRTA2 LOC106004130 LOC101688387 LOC101681906 LOC106006380 LOC101681454 CCDC83 LOC101688633 LOC106005634 LOC101686882 LOC101682503 Top 500 down genes for SARS-CoV-2 infection Day 21 in ferret nasal turbinates from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 SLC5A2 IL6 CUBN TCF12 SLC25A21 FBLN5 JAK2 HOOK3 SERPINE1 FRMD6 FLT1 MTMR11 TMEM173 FBN2 USP15 MAP3K1 CHD1 LRRC40 VPS13B KDR YARS2 RBM39 TGDS BCL2A1 NPHP3 POU5F2 RGS2 RBPMS MCTP2 THRB FOXP2 PAX9 ZEB1 UTRN INPP4B GPRC5A SORBS2 CCL8 ZBTB20 ARID5A ITGA5 ZYX ARHGAP29 TMTC2 ITGA1 RGS16 BRCA2 MERTK DTL ZNF365 AKAP5 LAMA2 EGR3 ATR SLC2A3 TRAK2 KLF11 B4GALT6 TGFBR1 PLAUR COL14A1 TFAP2A BNC2 LEF1 WNT9B ATF3 PTHLH MEF2A ELP4 HACD1 IL10RA RGS1 MTFR2 CHEK1 LCP2 PIK3R5 GEN1 KCNA1 PLIN4 SELE ACKR1 ADAMTS4 COL24A1 CNR1 NAV3 SOCS3 RIMKLB SLC3A1 BTG2 ZFP36 CYR61 IER2 FOS SNRK GRASP DUSP1 FOXF1 PTPRB JUN RBMS1 ADAMTS15 MGP SNRNP48 ESAM CCNL1 TCF4 PHLDB2 NRP1 CCNL2 VCL GEM NTRK3 PI15 TGFB1I1 EGR2 CNKSR2 KIAA1551 HMCN1 TCERG1 LRRK2 TNFAIP3 ADAMTS3 IL23A ZNF596 ADRA1A ZNF292 HTR2B FLRT3 CSRNP1 ZSWIM6 BHLHE40 MAFF NFKBIZ FOSB VMP1 PAN3 SEC24B PCSK5 VAV3 PLEKHH2 DUSP10 TNFRSF19 SLC38A6 ARGLU1 MSANTD2 METTL25 BLID TBL1XR1 CREBRF TTC21B GLMN CEP192 VEGFC FANCG PLCB1 RASA1 REL HFM1 ACOT12 ADAMTS6 CREM USP25 MAP3K8 RIPK2 RASL11A PRPF39 FNBP4 PRPF38B THSD7A SLC20A1 FAM111B N4BP2 ARID4A XRN1 ORC4 GORAB ZRANB2 RRH FNIP1 THOC2 DGKH SLC25A36 CD83 ETS2 OSR2 PLK2 CDK17 RCAN1 NPY1R MTF2 SF3B1 SRSF11 CD44 KANSL1L PDE7A ADAMTS5 ZNF280D PDLIM3 BACH2 PIGA SRSF12 ALX1 MCAM GPR21 RGS8 ADAMTS9 SCN2A PRTG SBSPON TAL1 RHOT1 HBS1L ITIH4 MDM4 KIT SOX5 MAP4K4 HDAC8 PPARGC1A NFKB2 NEDD4 RYR3 SULF1 RIN2 FLT4 DCAF4 ZCCHC7 ZNF326 CCAR1 PTPN2 CCNT2 CPS1 MIOS NEXN TENM1 EPC1 ELK3 VPS37B PPP1R12A SREK1 GLS AMPD3 PRKD1 LRP2 ITIH3 NPR1 MPDZ FAM13C MAGI2 TDRD6 LPP GTF2A1L JMJD1C SLC2A12 RUNX1T1 SLC9A9 VPS52 PRKDC APAF1 ZNF800 ZSCAN25 SAMD8 ZDHHC17 PARP4 LAMA4 CDK8 SFPQ WSB1 CBLB PXDNL ADGRG6 ZNF280C TIAM2 GGNBP2 FGD6 MLLT10 DLC1 CLK4 MYSM1 REV3L ANKRD50 RNPC3 FAT4 CCDC50 MCTP1 ANKRD28 PDE3A STAG1 PHF20L1 PAXBP1 BICC1 CAMSAP2 CREBZF 7-MAR ZZZ3 RALGAPA1 FBXO38 PSPC1 RAPGEF6 SOS2 PHKA1 LRCH1 TTC28 SYNPO2 SLC7A2 DOCK10 ARHGAP15 PRPF4B CEP85L ATAD2B IKZF5 TYW5 NID2 SFMBT2 DOCK4 RELL1 PTPN20 CNTLN PPIP5K2 CAMK1G SESTD1 RBM45 NKTR MCM8 SENP5 ESYT2 PDS5B CCSER2 LDB2 MSS51 FCHO2 FAM76B SCML1 HECTD2 GCFC2 SYCP2 AP1S2 ZNF518A TMEM161B FER CRYBG3 ELMO1 ADAMTS20 RAPGEF4 RAPGEF5 MYO9A PCNX ANGPTL7 CTNNA3 NBEAL1 SRSF10 FHL5 EED RBM26 RIC1 TRMT44 DDX46 DPH6 GREB1L DDX52 MTFMT RIF1 DACT3 ARHGAP28 ZNF300 RHOJ PHF14 PCDH18 DCHS2 FREM1 SNED1 GPATCH2 ZNF521 SNCAIP C1QTNF7 ZCCHC11 RAD51B LRCH3 COQ3 CARF KRIT1 ZNF644 TDRD3 DIAPH2 NDUFAF5 HSF5 MOBP LOC101690776 LOC101679775 LOC106005017 LOC101679005 LOC106003850 LOC101677582 LOC101692719 LOC106005567 LOC106005908 LOC106004978 ERC2 LOC101671834 LOC101676573 LOC101682519 KERA LOC106003800 LOC106005566 LOC106007462 LOC101682202 LOC106005051 LOC106003306 LOC106006840 LOC101681618 LOC101680631 LOC101692162 LOC106003319 LOC106005762 LOC101673309 LOC101680057 LOC101686429 LOC106004738 LOC101672982 LOC101670684 LOC106005832 LOC101674688 LOC106007154 LOC106004036 LOC106004647 LOC101679208 LOC101693690 LOC101686140 LOC101682383 LOC101674458 LOC106006120 LOC101681919 LOC101692727 LOC101680791 LOC106004689 LOC106003946 LOC101677143 LOC106003730 LOC101688785 LOC101685008 LOC106004784 LOC101676209 LOC101684148 LOC106005591 LOC106006942 LOC101686198 LOC101680623 LOC106005583 LOC106007338 LOC106005647 LOC101690273 LOC101673182 LOC106003323 LOC106006682 LOC101682876 LOC101689705 LOC101692993 LOC106005444 LOC101673805 LOC106004179 LOC106004536 LOC106006006 LOC101673739 LOC101683444 LOC106005814 LOC101680794 LOC101682130 LOC101682453 LOC101677760 LOC101686051 LOC101680813 ST8SIA2 LOC106004099 LOC106005531 LOC106007124 LOC101671551 LOC101683581 LOC101672663 LOC101681735 LOC106006299 LOC101672378 LOC101679735 LOC101692246 LOC101679587 LOC106004316 LOC101676879 LOC101691378 LOC101692158 LOC101691311 LOC106004794 LOC106006212 PAPD4 LOC106003403 LOC101687488 LOC101690609 LOC106007410 LOC101688772 LOC106005652 LOC106004180 LOC101675279 Top 500 up genes for SARS-CoV-2 infection Day 2 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 GHRH FBXW5 RPL36 DGAT1 HRAS BCKDK TSPO RRP9 TMUB1 CCND3 TLR4 CXCL16 UBXN1 PFKL MRPS2 GPAA1 PITRM1 UBTD1 GPX1 RBCK1 ACAA1 PLS1 TMEM61 CTSD ST3GAL4 TRIM25 POR ISG15 SRC AGPAT2 ACADS ICAM3 MYD88 RHBDD3 WDR34 EXOSC4 MCAT NAGLU BCL2A1 NINJ1 IGSF6 CD180 CKS2 STARD10 TAGLN2 ATP10A POLG SLC12A9 UNC93B1 NADSYN1 ITGB2 ARID5A LSP1 MYO1G TMC6 ARHGAP4 C1QC USF1 RIC8A MICAL1 ARHGEF10L CHID1 AKT1 GAA TBC1D10B SPN CORO1B DOK2 EHBP1L1 SLC15A3 TBC1D10C TKT GRN WDR13 PPP1R12C LTBR SLC38A10 GALNS SLC11A1 GLMP CAPG CEBPA RAB20 ADAM15 PSEN2 NDUFS7 OTOF ATP6V1F TMEM150B IRF5 MPND ADORA3 GALK1 ABCD1 MAP3K6 SIGIRR GPR68 CHI3L1 CST7 MATK HRH4 SLC2A6 MARS MMP1 B4GALT7 MMP11 STAT5A GJB3 ZBTB42 TONSL EEF1D ARHGEF16 SLC4A2 AXIN1 IRF8 ZNF628 ZMYND15 CYHR1 PICK1 EME2 RXRA SYTL1 PLEKHG3 OGFR BSPRY LRCH4 CD69 IRF7 PSTPIP1 ZBP1 RINL AOAH TNFSF14 TAP1 PLD4 GZMA ITGB7 SECTM1 CD72 CORO1A CENPM FAM78A LY86 GLIPR1 COTL1 CTSS CFD MYBPC3 PSMB8 FOLR2 DHX58 CD5L IL1R2 TREX1 ARL11 PLAC8 TNFAIP6 TCIRG1 TINAGL1 NFKBIE ADAR GLIPR2 HSH2D IL4I1 IFI35 SOCS1 GPR35 SAMHD1 UBE2L6 UBA7 PSME1 PSME2 RPL8 PSMB10 CTBP1 HPCAL1 GSTP1 PSMB9 CHCHD2 RPS21 PPP1CA ATP5D BNIP3 RPS9 OAZ1 IL3RA NDUFB7 STUB1 ADRM1 TYROBP TALDO1 HN1 LIMD2 LAPTM5 TMEM259 EDF1 HCK EFHD2 PGLS SAMSN1 LST1 RGS14 MBP CYTH4 TNFRSF14 HMHA1 LAMTOR2 CIB1 PFDN2 SLC25A11 DAP3 CCDC124 NHP2 RNF151 ZNF513 SDHAF2 AHSA1 SSR2 TUFM CPN1 SRPK3 SNAPC2 BTBD6 CTDP1 NUDCD3 SUSD3 LAT2 DNASE2 IL15RA MB21D1 BID GSDMD SSNA1 BATF3 TPGS1 CAPN14 IL32 MAD1L1 METRNL IDH2 LRRC45 LMNB2 LGALS9 MRPS11 HERC5 TMEM140 ZBED1 BOP1 ORC6 ARPC1B ERAP2 PARP3 OPTN HOGA1 RNH1 CDA ANAPC2 PLSCR1 ADORA2A NCF1 PPM1J ACP5 SEMA4D TRAPPC5 GPR132 RGS19 FGD3 BSG TFEB CLPP TNFRSF1B SYK MRPS12 GBA PPP4C MOB3A HAGH TRAF2 AP5Z1 AURKAIP1 CHKB APRT ALDH3B1 PLEKHJ1 STK25 SLC25A10 ORAI3 MPST CCS THAP7 DDX54 NUBP2 STRA13 MAN2C1 NARFL SPNS1 ADCK5 HMG20B FAM173A SLC16A13 DUS3L ASNA1 LRP3 RABEP2 GNPTG SIRT7 FBXL8 TTLL12 AMDHD2 CAPN10 MBD3 MFSD12 TMEM129 PYCR2 PQLC1 DAPK3 CCM2 TIMM13 NCAPH2 STARD3 NOC2L UBE2J2 PLEKHM2 TSSC4 FDPS ERCC1 ARFRP1 TNIP2 PHLDB3 EGLN2 PLIN3 DEAF1 LRPAP1 ADCY1 DNPEP KEAP1 CDC34 NT5C3B BHLHA15 EIF4EBP1 PRR5 ATG4D VAC14 DHPS STK11 ZBTB17 HDAC10 REXO4 ZMYND19 RCC2 RECQL4 FAM207A NFKBIB MAP2K2 TMED3 MRPL23 JOSD2 RMI2 BCL7C PDDC1 IGHMBP2 AEN GPS1 HES6 PCYT2 GAMT RBFA GNA15 STOML1 CNP WRAP53 SLC39A3 ZNF771 FBXL19 CACTIN PRR7 NDUFS8 SPAG7 PDLIM4 TMEM161A PFKP GPR161 MRPL57 TMEM134 FAM53A WBP1 DBNL CARD9 THAP3 TBRG4 P3H3 SYNE3 TMEM120A OGFOD3 ABHD17A RASSF7 PUS1 PRPF31 UBAC1 GTF2F1 SMG5 DDX51 TSC22D4 FAM195B ARFGAP1 PGS1 ABT1 TRABD DUS1L SLC25A6 ZGPAT FAM195A CPSF3L STK19 SPSB2 FBXL14 TBC1D22A MICALL2 CSNK1G2 MPG DTNBP1 MON1A LIME1 RTEL1 TRMT61A SURF1 WDR83 D2HGDH NELFB TMEM125 CHCHD5 HS3ST6 ARHGAP22 SLC35C2 TMIGD2 WBSCR16 PPAP2C FLAD1 LOC101674184 LOC101683191 LOC101670560 LOC101691795 LOC101684595 LOC101677848 LOC101672891 LOC101688417 LOC101684101 LOC101687773 LOC101689258 LOC101680253 LOC101670985 LOC101672987 LOC101681255 LOC101672794 LOC101687145 LOC106003421 LOC101679372 LOC101686692 LOC101690749 LOC101684888 LOC101686433 LOC106005467 LOC101685649 LOC101684072 LOC101674608 LOC101692710 LOC101693539 LOC101693436 LOC101694055 LOC101674154 LOC106004464 LOC106004638 LOC101691884 LOC106004313 LOC101690652 LOC101683501 LOC101681179 LOC106007238 LOC101679074 LOC101675755 LOC101679249 LOC101677588 LOC101677139 LOC101674076 LOC106005426 LOC106004560 LOC101689785 LOC101677791 LOC101685995 LOC101692534 LOC101675923 LOC106004259 TSEN54 RPS7_1 LOC106003683 LOC101689877 LOC101675922 LOC106004311 LOC101675409 LOC106004309 Top 500 down genes for SARS-CoV-2 infection Day 2 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 FAM8A1 ATE1 RB1 APLNR EGR1 PTBP2 ASAP2 MACF1 DAAM1 MIB1 IL17RD MAST4 ETV1 BRAF USP13 HOOK3 UGGT2 FLT1 ENPEP ATM NR3C2 COL4A4 PDE4D USP54 PPIG EDEM3 GSK3B LNPEP RAB11FIP2 GPHN NR3C1 ZBTB44 FBXO8 KLF12 ZKSCAN1 MYO6 MED14 NBEA CP ITGA2 SRGAP1 NEBL SLC4A4 SH3RF1 COBLL1 NFAT5 NFIB RNF152 PEAK1 QSER1 TCP11L2 CDC14B FAM214A ZEB1 UTRN SSBP2 TJP1 NFIA ZBTB20 ZNF462 ARID5B AREG ARHGAP29 LHFPL2 CTNND1 ITGA1 HGF LAMC1 CALCRL CDC42BPA RAPH1 MPP6 ABCB1 PDGFD ITGB8 PTCH1 AKT3 PTGS2 TFDP2 TGFBR3 EFNA5 PLCXD3 KLF11 FOXO1 DSP BCAS3 PYGO1 LRP6 BNC2 LEF1 PRICKLE2 ABI3BP NR2F2 STIM2 WNT2 SOX6 SLC8A1 KIF13B PDLIM5 SMARCA1 AAK1 STON1 ANGPTL2 RIMKLB BTG2 DPYSL2 CLIC4 ETS1 BMPR2 THBD FOS RASGRP3 CYYR1 PTPRB TSPAN7 RAPGEF2 CTGF NPNT SPECC1L PDE5A NR1D2 HIPK3 PLXDC2 RBMS3 NRP1 SMAD4 NUCKS1 VCL NOVA1 PTGER3 AOC3 CCND2 SULT1E1 HMCN1 SGIP1 ANO3 ZNF292 TP53INP2 KLHL15 TSC22D2 PJA2 PAN3 UGT8 TIMP2 DHX40 SEC24B SERINC5 TNFRSF19 PDE4B KLF7 MBD5 KDM3B CREBRF KLF3 KLHL24 MAP2 SCAF8 ATXN1L PTPRD KDSR MCC CDH6 TMEM200A PCDH9 PLCB1 RASA1 PSD3 ADAMTS6 THAP9 TEX14 NTNG1 BMPER GPR63 ARID4A SMAD5 SEMA3E NPR2 XRN1 LRIF1 CCNT1 ZNF461 SPAG9 NIPBL ZBED6 MEIS2 PPP1R9A ATRX CRIM1 SCAMP1 DGKH RFX7 CPEB2 TRIB2 AKAP11 CDON IGIP ZNF280D ATF7IP FLRT2 KBTBD3 FRY RBM12 BACH2 HHIP SLC26A7 GPR21 KRT24 SCN5A ABCA12 PRKG1 SV2C KLHL14 CACNA1E ITGA6 UBE2B RIOK3 MDM4 CDK6 GNAQ ROS1 SPRY1 TIMP3 NEDD4 EXOC2 TIGD1 AHNAK NELL2 ZC3H11A FIP1L1 PHC3 ATP7A HELZ ZBTB10 WDR44 ZNF326 PPP2R2A FAT1 PODXL ELK3 DST PPP1R12A WASL SP1 ZBED5 INSIG2 GDA MPDZ ARHGAP5 JAZF1 DGKI FAM13C SETD7 NCOA2 LPP ADGRF2 SENP7 PLD5 ARHGAP32 NF1 GPM6B DPY19L3 TRA2A PIK3C2A PCM1 MBOAT2 EIF5A2 PROX1 PEG3 PCDH17 EPG5 TFPI UBR5 NDUFA4L2 APOA1 LEPR TMEM106B SLC30A1 PLD1 ZNF800 ZMYM6 ZNF449 ZCCHC4 ZFHX4 PCYT1B TRIP11 UBXN7 ZDHHC17 SLC16A2 CBLB WWP1 ABI2 PPIL4 LATS1 ANTXR1 SP4 SMC1A LEPROTL1 TIAL1 GPC4 TCAF1 CNOT4 GAPVD1 FGD6 BICD1 LRIG2 CLK4 TMX4 DSC3 SEMA6D DZIP3 PGAP1 ANKRD50 LANCL1 CPD UBN2 FAT4 PPP1R3C VGLL3 PHIP GXYLT1 EIF4EBP2 TRPC1 KDM5B GFRA1 ZC3H6 JMY LGR4 FRS2 ATRN PTPRK MED13 BICC1 CAMSAP2 KAT6A HIPK1 OPHN1 BTBD7 TMEM2 DENND5B RPRD2 KMT2E RALGAPA1 BAZ2B CREB3L2 EVI5 ZNF248 TBC1D32 PIAS2 HECW2 PALLD SCAI CPEB3 ARID4B FRYL SLIT2 SEMA3D FAM168A PRG4 CROT NADK2 SLC7A2 6-MAR CEP85L SMNDC1 USP37 RASSF9 HCFC2 SVEP1 SGCB PPM1E BDH2 ACACB SESTD1 NDNF GAB1 ARHGAP42 ZNF652 ANKRD26 BPTF NHLRC2 GTF2A1 SAV1 PDS5B FAM63B CLOCK ATP2B4 HMBOX1 CCSER2 RNF38 SPATA6 RORA GABRA2 NAP1L3 CDC73 FCHO2 MOB1B TWSG1 SPOPL YLPM1 SGTB SKAP2 MAPK1IP1L ATL2 TAOK1 FAM135A HOXA4 ADNP NPAT PAFAH1B1 KCNT2 GUCY1A2 CACNA2D1 OPCML WASF3 MYO9A CDKL5 TMOD2 NBEAL1 GPC6 ARHGAP20 USP46 PKN2 CPSF6 DPH6 CHN1 TRIM33 DUSP19 MMP16 ACVR2B CTTNBP2NL PCDH18 DCHS2 STXBP4 CACHD1 PTPRG ERCC6L2 MAML2 CIR1 LRCH2 DACH1 C1QTNF7 FAM124B INSC INSC ZCCHC11 WIPF2 NOVA2 ADGRL4 CARF ZC2HC1A SLAIN2 ZBTB37 TMEM26 DPP6 FNDC1 EPHA5 DHX57 CASP8AP2 LOC106003800 LOC106003319 LOC101672982 LOC106006686 LOC106003548 PURG LOC101691437 LOC101687351 LOC101669926 LOC101677652 LOC101694604 LOC106003323 LOC101679698 LOC101682876 LOC101687368 ST8SIA2 LOC106007124 LOC101679587 LOC101676402 LOC101680703 LOC101679280 LOC106006213 LOC101689246 LOC106006804 LOC106007252 LOC101674563 LOC101678424 RXFP3 LOC101674285 LOC101692572 LOC101670318 ASPA LOC101671028 LOC101671185 LOC106003787 LOC101670871 LOC101688444 LOC101670390 LOC101688667 LOC101676955 LOC101672604 LOC101674734 LOC106003300 Top 500 up genes for SARS-CoV-2 infection Day 7 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 CHPF2 MVP FBXW5 RPL36 DGAT1 BCKDK TSPO RRP9 TMUB1 UBQLN4 PFKL TUBB4B MRPS2 ZBTB7B ASPSCR1 GPAA1 UBTD1 GPX1 ACAA1 CTSD TUBA4A CNDP2 POR PLD3 NPLOC4 SHARPIN FERMT3 SRC IL17RA AGPAT2 FBP1 ICAM3 SPI1 GNMT SEPHS2 RHBDD3 WDR34 WDR24 EXOSC4 SAC3D1 NAGLU ENO1 BRF1 LCP1 NINJ1 S100P TSTD1 CKS2 TACSTD2 RPL7A AIF1 STARD10 FTL RELT POLG ANKRD13D UNC93B1 ARHGAP30 MAN2B1 NADSYN1 ITGB2 ARID5A LSP1 MYO1G TMC6 ARHGAP4 C1QC SH3TC1 MICAL1 ARHGEF10L DPP7 PGD VASP C1QA RPS6KA1 AKT1 PNPLA6 LRRC25 GAA CD37 CORO1B DOK2 UNC13D PSD4 SLC16A3 EHBP1L1 TBC1D10C TKT GRN TOLLIP WDR13 PPP6R2 HK3 PPP1R12C LTBR SYNGR2 SLC38A10 GALNS NCLN CAPG MRPL12 RAB20 ADAM15 PSEN2 NDUFS7 ATP6V1F CTSZ TNFAIP8L2 COMMD9 GALK1 TRPM2 CLTA CLDN7 SIGIRR MATK PLCXD1 SLC2A6 BAD CKS1B STAT5A BATF ZBTB42 CLDN4 ELMO3 TONSL SSH3 ARRDC1 EEF1D MST1R ARHGEF16 SLC4A2 CLU WNT3A ABCA7 DVL1 BIN1 PWWP2B DHX34 CEBPB CYHR1 PICK1 SLC12A7 RXRA SYTL1 PITPNM1 PLEKHG3 OGFR LRCH4 TMEM8A MBOAT7 HCLS1 CD48 SLC37A2 CFB PSTPIP1 RINL CKAP2L PLD4 RASAL3 GZMA TACC3 CCDC88B ITGB7 RAC2 CORO1A FAM78A FCHO1 GLIPR1 COTL1 MYO1F PTPN7 CFD MYBPC3 DNPH1 CCR1 ARL11 TCIRG1 PIM1 NOD2 RPL28 PFN1 CNN2 CTBP1 HPCAL1 GSTP1 RPS21 CTSH ATP5D RPS9 OAZ1 STUB1 ADRM1 TYROBP IFI30 TALDO1 LIMD2 LAPTM5 TMEM259 HCK NCF4 FASN EFHD2 RASSF5 PGLS LST1 RGS14 MBP CYTH4 NPDC1 ZNF205 TNFRSF14 HMHA1 LAMTOR2 CIB1 DPP3 DAP3 NHP2 LSM7 MGLL SSR2 TUFM SRXN1 SURF2 ARRDC2 SMIM1 BTBD6 CTDP1 MVD NUDCD3 GRAMD4 SUSD3 LAT2 GSDMD NOXA1 GCHFR NCKAP1L SPNS3 WAS SNX20 TRAF3IP3 BATF3 DGAT2 FES GCAT NFE2 PAQR6 METRNL LRRC45 LMNB2 ZBED1 BOP1 ARPC1B PARP3 TM7SF2 MTX1 PTPN6 RNH1 CDA CBS ANAPC2 SLC17A9 P2RY8 NCF1 ACP5 SEMA4D SURF4 TRAPPC5 PILRA GPR132 FGR RGS19 DOK3 FGD3 BSG TFEB TNFRSF1B SYK GBA PPP4C BDH1 SPP1 NUDT8 AP5Z1 CHMP1A AURKAIP1 CMTM7 CLN3 APRT ALDH3B1 STK25 ORAI3 MPST DDX54 FAM118A AGPAT3 FGA TBL3 FAM173A SLC16A13 DUS3L P2RY2 TSTA3 LRP3 GLI4 GNPTG SIRT7 TTLL12 AMDHD2 CAPN10 MBD3 MFSD12 PTPN18 TMEM154 PYCR2 PPP1R14B PQLC1 DAPK3 RHBDF1 CCM2 TIMM13 NCAPH2 STARD3 TCF25 UBE2J2 FDPS ARFRP1 TNIP2 RIPK4 EGLN2 DEAF1 IL6R LRPAP1 ADCY1 ADGRE3 BHLHA15 PGP GPC1 PRR5 ATG4D VAC14 ARSA TNFSF13 DHPS STK11 ATP13A2 S1PR4 ZBTB17 FZR1 REXO4 PRCC FAM207A MRPS34 GRK6 DOCK2 NFKBIB MAP2K2 TMED3 ENO3 PLCG2 MAPK8IP1 TEX264 NAPRT MRPL23 IGHMBP2 GPS1 DHCR7 PAGR1 PACSIN3 MAPKAPK3 PKDCC PCYT2 GAMT GNA15 MFSD2A FADS3 CNP SLC39A3 OTULIN NDUFS8 UCKL1 PDLIM4 GALE 9-SEP GPR161 MRPL57 TMEM134 WBP1 HOOK2 DBNL LDHD PKN1 CARD9 THAP3 ST6GALNAC4 TBRG4 LOC101673770 OGFOD3 ADCK3 ADRBK1 PUS1 PRPF31 GTF2F1 SMG5 GLTSCR2 E4F1 TSC22D4 TRABD DUS1L SLC25A6 ZGPAT FAM195A SPSB2 KLHL22 MESDC2 FBXL14 TBC1D22A PTRH1 CSNK1G2 ENGASE MPG OGFOD2 OXER1 RTEL1 TRMT61A TMEM191C B3GAT3 SURF1 ZNF839 UNC119 CDPF1 HEXDC NELFB HS3ST6 BCAS4 SLC35C2 POU2F3 PPAP2C FLAD1 LOC101670738 LOC101674675 LOC101693321 LOC101684101 LOC101694369 LOC101687773 LOC101672987 LOC101672794 LOC101692964 LOC106003421 LOC101682491 LOC101674688 LOC106003381 LOC101691605 LOC101681077 LOC101684888 LOC101685649 LOC101693539 LOC101674154 LOC106007238 LOC101679074 LOC101677139 LOC101674076 LOC101689785 LOC101692534 LOC101675923 LOC106004259 LOC106003683 LOC106004311 LOC101682527 LOC101678746 LOC101692362 LOC101684100 LOC101691890 LOC101693046 LOC101678542 LOC106004248 LOC101686007 LOC101675567 LOC101678474 LOC106003628 LOC101683221 LOC101681506 ENTHD2 LOC101682410 LOC106003339 LOC101692736 LOC101684878 LOC101675320 LOC101693860 LOC101670624 LOC106003865 LOC101688388 LOC101669906 LOC101680639 LOC101675405 LOC106003741 LOC101676319 LOC101680350 LOC106003565 LOC106005943 LOC101671355 Top 500 down genes for SARS-CoV-2 infection Day 7 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 RB1 NOX4 TRIM59 PTBP2 ASAP2 MACF1 LSAMP MIB1 UBE2K CACNA1D MAST4 ETV1 UBE2D1 EHBP1 UGGT2 FRMD6 FLT1 RAB18 NCKAP5 PDE4D PPIG ING3 EDEM3 HS2ST1 FRMD3 NR3C1 LRRC40 FBXO8 SLC25A16 TRIM23 MYO6 MED14 FBXL3 SH3D19 NEBL BEND7 GULP1 THRB NFAT5 RNF152 PAWR NCKAP1 QSER1 TCP11L2 PTGFR ZEB1 UTRN ZBTB20 THBS1 NREP ARHGAP29 LHFPL2 ASPM ITGA1 HGF CALCRL OLFML2A RAPH1 ABCB1 SGCD AKT3 LAMA2 YPEL1 AKAP12 TGFBR3 HINT3 TRAM1 KLF10 PKD2 KLF11 PIK3CA EDN1 FOXO1 IMPA1 BCAS3 PYGO1 LRP6 NKD1 FGF7 PRICKLE2 ABI3BP FGF12 NR2F2 DIXDC1 WNT2 SLC8A1 KCNJ3 CHL1 NTRK2 CHRM2 STON1 MAMDC2 ITGA8 ANGPTL2 RIMKLB CLIC4 THBD PPP1CB TXNIP PTPRB UBL3 NPNT PDGFRA OGN SPECC1L LIMCH1 PDE5A NR1D2 DDR2 PLXDC2 LRRC58 NPR3 CHORDC1 PHLDB2 NRP1 YTHDC1 SMAD4 NUCKS1 BNIP3L NTRK3 STARD9 AOC3 TRPC3 LIX1 SRPX CCND2 SULT1E1 EGFLAM HMCN1 SGIP1 ZNF484 KLHL11 EDNRA ANO3 PPAP2B ZFP37 ZNF292 KLHL15 FLRT3 GOLT1B UGT8 RPS6KA3 TMPO LAMB1 SEC24B NEK7 FOXF2 DNAJB4 ZBTB8A TMEM55A PLEKHH2 CUL4B TNFRSF19 PDE4B TMEM47 KLF7 CREBRF KLF3 KLHL24 MAP2 HIVEP2 PTPRD LGR5 CDH6 TMEM200A PCDH9 PSD3 TCEB1 HFM1 ADAMTS6 PDK4 RAD1 TEX14 BMPER DRD1 ARID4A SMAD5 USP44 CCNT1 KIAA1033 CCDC186 SMURF2 LTN1 SCAMP1 DGKH SLC25A36 CDK17 HDX MARVELD2 ARL5B BPGM MMD LPAR6 KANSL1L ZNF280D CACNB2 KBTBD3 HHIP ENPP2 CALD1 PRTG PRKG1 SV2C SIAH1 DHX36 POT1 UBE2V2 UBE2B RIOK3 CREB1 RECK SPRY1 CA12 RNF11 NEDD4 TSNAX EXOC2 FKBP14 VTN ZNF569 TIGD1 BNIP2 ARL5A DNAJB14 PHC3 RIN2 ZBTB10 CUL3 PTP4A1 ZNF326 MIER1 TENM1 ELK3 DST SPRED1 OCLN ROCK2 MTUS1 ROBO2 SYDE2 GDA ARHGAP5 FAM13C USP9X SEMA6A KDM6A MAGI3 SENP7 PLD5 SLC2A12 KRAS BMI1 TBC1D12 EIF5A2 TTPA PRKAA1 PROX1 CACNA1C PEG3 PCDH17 FAM133B RAB33B FBXO32 NDUFA4L2 LEPR TMEM106B SLC30A1 ZMYM6 ZNF383 HACD4 PCYT1B TBC1D15 UBXN7 ZDHHC17 LAMA4 UGCG PPIL4 UGDH SP4 LEPROTL1 GPC4 TCAF1 THAP1 MTMR9 ZNF280C FGD6 ZFX DLC1 SKIL CLK4 MYSM1 DZIP3 DPY19L4 PGAP1 ANKRD50 DCUN1D1 FAT4 VGLL3 PHIP MANEA TROVE2 AEBP2 SBF2 TRPC1 CLDN12 GFRA1 JMY LGR4 PTPRK BICC1 CAMSAP2 LEMD3 CCDC82 TMTC3 OPHN1 BTBD7 TMEM2 NEK1 FOXN2 EVI5 ZNF248 TBC1D32 MICU3 SLC25A30 HECW2 PALLD TTLL7 SCAI PRKAB2 GJC1 CDK14 CPEB3 ARID4B ZC3H13 MZT1 LRRCC1 SYNPO2 SLIT2 TRPC4 CROT NADK2 SLC7A2 ZNF281 CEP85L RASSF9 SNX16 HOXA3 HCFC2 SVEP1 SGCB DOCK4 PCMTD1 RNF138 G2E3 DTWD1 PPM1E RPS6KA6 BDH2 FAM126A MTURN NDNF ARHGAP42 ANKRD26 NHLRC2 GTF2A1 SAV1 PDS5B DCUN1D5 FAM63B ATP2B4 CCSER2 FYTTD1 EIF1AX ANKRD46 RORA GABRA2 LDB2 CDC73 TWSG1 ZDHHC2 SPOPL HECTD2 SMARCAD1 KATNBL1 LRP12 PLEKHA3 MTMR6 PREPL ATL2 HOXA4 FAT3 CEP97 ZNF706 FBXO30 AKAP6 KCNT2 ZNF385D GUCY1A2 CACNA2D1 OPCML GALNT13 WASF3 PLXNC1 TMOD2 ODF2L DNAJC24 GPC6 PKN2 CPSF6 MYEF2 ICE2 CHN1 TRIM33 RIF1 CCDC169 DUSP19 MMP16 PAPOLG PHF14 PCDH18 DCHS2 FSD1L PHEX KATNAL1 FAM19A2 FREM1 MFSD4 LRCH2 ASPN C1QTNF7 PDZRN4 PDZRN4 ARL6 GUCY1B3 LRCH3 ADGRL4 PRELP ZC2HC1A ZNF644 PABPC5 AHI1 DIAPH2 TMEM26 FAM162B RPA4 EPHA5 CASP8AP2 LOC101671862 LOC106003850 LOC106003306 LOC106003319 LOC101686429 LOC101672982 LOC106006686 LOC101688940 LOC106003548 LOC101687369 LOC101691437 LOC101669926 LOC101694604 LOC106003323 LOC101679698 LOC101682876 LOC101679587 PAPD4 LOC101676402 LOC101678424 LOC101674285 LOC101692572 LOC101670318 ASPA LOC101671028 LOC101670871 LOC101670390 LOC101688667 LOC101676955 LOC101674734 LOC106003300 LOC101686772 LOC101694147 LOC101680580 LOC101683238 LOC106003573 LOC101694275 QRFPR LOC101676723 LOC101693028 LOC106003457 LOC106006044 LOC106004181 LOC101683348 LOC101692986 ZNF568 LOC101673446 LOC101684181 LOC101671813 LOC101680548 TMEM215 LOC106003380 LOC101677578 LOC106003991 Top 500 up genes for SARS-CoV-2 infection Day 14 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 GOT1 TIMM10B TRIM55 TRMT1 FBXW5 RPL12 RPL36 CDH17 RRP9 TMUB1 ARRB2 TMEM97 TUBB4B ASPSCR1 FAM109A UBTD1 GPX1 ACAA1 FBL TMEM61 TUBA4A ACADVL CNDP2 NT5C IL12RB1 FAU TTC38 FERMT3 IL17RA CD244 PTGES2 FKBP1B ICAM3 SEPHS2 WDR34 NPY NDUFV1 MCAT ENO1 BRF1 RPS16 PCP4L1 CRYM SCIN TSTD1 CKS2 RPL7A STARD10 FTL RELT SLC12A9 ANKRD13D ARHGAP30 ITGB2 LSP1 MYO1G ARHGAP4 RIC8A MICAL1 DPP7 PGD RPS6KA1 AKT1 PLCB2 LRRC25 EHBP1L1 TBC1D10C TKT PPP1R12C MRPL12 CEBPA FZD2 RAB20 ADPRH MZB1 FGD2 TMEM150B IRF5 SHMT1 MPND TRPM2 GAPDH PADI2 NAGA ALDH4A1 PRELID1 SIGIRR GPR68 MATK PLCXD1 SLC2A6 CKS1B RPS2 MMP11 STAT5A HPGDS LAD1 EPN3 TONSL EVPL ARHGEF16 SLC4A2 AXIN1 IRF8 DVL1 PWWP2B SYTL1 PITPNM1 OGFR LRCH4 HCLS1 ZAP70 CD48 PSTPIP1 SH2D1A HCST DEF6 GZMA CCDC88B CD72 CORO1A FAM78A SLAMF9 GLIPR1 COTL1 MYBPC3 PSAT1 CD5L KYNU ARL11 TNFAIP6 ACOXL S100G FGG TCIRG1 PIM1 GPR35 CCL19 RPL28 RPL8 CNN2 SMDT1 HMGCS1 GSTP1 RPS19 S100A4 RPS5 RPS21 ACAT2 PPIB NDUFA13 PSMB6 PRDX5 VPS28 ARL6IP4 NDUFS6 RPL18 RPS9 OAZ1 IL3RA RPL18A STUB1 TYROBP CCT3 TALDO1 HN1 MRPL28 LAPTM5 GPI SELENBP1 HCK CSF2RA NCF4 RASSF5 GLRX5 NDUFB10 TMEM256 PGLS SAMSN1 RGS14 SLA CCR8 MBP KCNN2 FAM129C HMHA1 UBE2S MRPL34 SLC25A11 APOA1BP DPP3 DAP3 RNF151 SDHAF2 HSD17B2 TUFM RPL29 PLEKHG6 RUVBL2 ARFIP2 INSIG1 CCDC64B MSMO1 SQLE MVD NUDCD3 VAMP5 SUSD3 LAT2 PPM1K NOXA1 PLK5 FCRLA WAS BATF3 TPGS1 PACSIN1 ACAP1 FES ISOC2 GCAT IL32 ABAT METRNL LRRC45 LMNB2 MRPS11 CYSRT1 MMEL1 ARPC1B TM7SF2 TAF10 BLVRB CUX2 CBS LPIN1 OSGIN1 SEC14L2 SLC17A9 CARD11 CLCNKA NCF1 C4BPB PPM1J CHN2 ADRA1B SEMA4D IKBKE GET4 COQ9 PILRA NAGK NCF2 RGS19 DOK3 FGD3 TRADD GDF5 TFEB SC5D MRPS12 STX4 PPP4C HAGH BDH1 SPP1 AP5Z1 AUP1 BOLA2B AURKAIP1 CMTM7 CHKB CLN3 APRT PLEKHJ1 STK25 ORAI3 CCS DDX54 STRA13 ST3GAL5 FAM118A TBL3 HMG20B FAM173A SLC16A13 RALY ASNA1 TSTA3 GNPTG NUDT14 SIRT7 LSS CAPN10 MBD3 MFSD12 MPC1 DDX39A PTPN18 PYCR2 PPP1R14B CCM2 TIMM13 STARD3 TCF25 UBE2J2 PLEKHM2 FDPS ERCC1 STX6 FCRL3 PHLDB3 EGLN2 FDFT1 MCCC1 DEAF1 LRPAP1 BFSP2 DNPEP NT5C3B TSPAN15 NVL RAB40C ARHGEF38 PGP MCOLN1 VAC14 SLC8B1 DHPS IVD STK11 SCN9A RAB24 ADGRG5 ZBTB17 HSD17B13 MCF2L2 CRAT DAO BRMS1 REXO4 HNRNPAB SHMT2 DOCK2 MAP2K2 NOX5 PLCG2 TEX264 AK1 PNKD NAPRT MRPL23 PDDC1 SLC25A38 SFXN2 DHCR7 PACSIN3 PMVK PCYT2 GNA15 MFSD2A FBXL19 NR2F6 OTULIN GRAMD1A NAA38 MRPL55 UCKL1 PDLIM4 GALE PFKP PAFAH1B3 GPR161 FAM53A PATL2 DBNL GCDH CARD9 ST6GALNAC4 MFAP3L SCN1B SYNE3 ELOF1 TMEM120A OGFOD3 IMP4 PRPF31 TIMM22 SMG5 GLTSCR2 DUS1L SLC25A6 TSR3 FAM195A CPSF3L SPSB2 MESDC2 MICALL2 CSNK1G2 TCEA3 SPATA6L OXER1 MON1A WDR83 METTL12 SLC25A19 BCO2 SURF6 ZNF839 SLC35F2 RASGRF1 UNC119 RIC3 TMEM101 CHCHD5 HS3ST6 SLC35C2 FUK CEBPE WBSCR16 FAM58A PPAP2C FLAD1 LOC101684891 LOC106004811 LOC101677848 LOC101674675 LOC101680253 LOC101672987 LOC101672794 LOC101681193 LOC101691116 LOC101676905 LOC101671415 LOC101684888 LOC101686433 LOC101685649 LOC101684072 LOC101693539 LOC101694055 LOC101674154 LOC106007238 LOC101679074 LOC101679249 LOC101677588 LOC101677139 LOC106005426 LOC101689785 LOC101692534 LOC101675923 LOC106004259 RPS7_1 LOC101692362 LOC101691890 LOC101678542 LOC106004248 LOC101686007 ENTHD2 LOC106003339 LOC101684878 LOC106003865 LOC101669906 LOC101675405 LOC101680350 LOC101689620 LOC101683998 MLNR LOC101684720 LOC101673624 PKD1L3 LOC106006421 LOC101678183 LOC106005645 LOC101682702 LOC101693584 LOC106003335 LOC101692368 LOC101685148 LOC101683217 LOC101694386 LOC101674033 LOC101690425 LOC106003292 LOC106003671 LOC106004696 LOC101675034 LOC106005610 LOC101675111 LOC101685910 LOC101669892 LOC106003448 LOC106004776 LOC101692462 CALML6 LOC101677073 LOC101692463 LOC106005611 LOC101691061 LOC101692051 LOC101680949 Top 500 down genes for SARS-CoV-2 infection Day 14 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 F2RL1 TBCA RB1 FKBP1A APLNR VCAM1 TRIM59 PTBP2 ASAP2 DAAM1 MIB1 UBE2K CACNA1D MAST4 ATXN3 XPNPEP2 ETV1 EPS15 HOOK3 MAPK14 RAB18 FN1 PLOD2 NCKAP5 NR3C2 PDE4D ELK4 PPIG HS2ST1 FRMD3 GSK3B GPHN FBXO3 ZBTB44 FBXO8 KLF12 GAL3ST2 SLC25A16 CPT1A MED14 SH3D19 SRGAP1 NEBL BEND7 TRPS1 GULP1 SLC4A4 SH3BGRL2 COBLL1 NFAT5 NFIB PEAK1 PAWR QSER1 TCP11L2 PRSS23 PLEKHG1 NFIA ZBTB20 ZNF462 THBS1 ITGA5 NRP2 NREP LHFPL2 HGF CALCRL BATF2 RAPH1 SPTLC2 PTCH1 MGAT4A YPEL1 GATA3 CAMK2N1 TGFBR3 NUAK1 B4GALT5 KLF10 PKD2 KLF11 PIK3IP1 B4GALT6 TGFBR1 PIK3CA FGFR1 FOXO1 LRP6 COL1A2 BNC2 AXIN2 ABI3BP NAV2 FGF1 FGF12 NR2F2 STIM2 JAG1 PNN SOX6 TNFRSF11B SLC8A1 TAB3 SMARCA1 PON1 KCNJ3 ENPP6 C3 CCNE2 STON1 ANGPTL4 NRIP3 PABPC4L MAMDC2 ANGPTL2 DPYSL2 CLIC4 BMPR2 CD200 IER3 FOS PPP1CB TXNIP TSPAN7 CTGF PDGFRA EFEMP1 NR1D2 TMEM176B PLXDC2 TP53INP1 ITPRIPL2 RBMS3 LRRC58 NUCKS1 IGFBP5 CREB5 GLI3 TAGLN3 CCND2 SULT1E1 EGFLAM HMCN1 SGIP1 ZFP37 KLHL15 FLRT3 PJA2 SDC2 TIMP2 KDELC1 RPS6KA3 TMPO SEC24B LCLAT1 MXI1 SOSTDC1 CUL4B TNFRSF19 TMEM47 KLF7 METTL25 MBD5 HOXA5 CREBRF KLF3 KLHL24 MAP2 HIVEP2 GNB4 CDH6 GXYLT2 TMEM200A IL1R1 CHSY3 PSD3 TCEB1 HFM1 P2RY13 PCGF5 PDK4 CHAD DYNC1LI1 CD38 CASS4 TEX14 NTNG1 AFAP1L2 BMPER SMAD5 RNF19B LRIF1 CCNT1 TOP1 SPAG9 ZBED6 CRIM1 IGF1R EMP1 PKHD1L1 SCAMP1 DGKH CDK17 HDX RCAN1 MARVELD2 ARL5B RBMS2 FMR1 GRIN2A MMD AKAP11 NAV1 CDON DISP1 IGIP ZNF280D KBTBD3 FLI1 MBLAC2 PAG1 COL12A1 ENPP2 SLC26A7 SCN2A SPRY4 MEGF10 SV2C ELAVL2 ITGA6 RAD21 UBE2V2 UBE2B CTCF CDK6 RECK TIMP3 FAIM2 NEDD4 TSNAX RAB21 DENND2A ADH4 BNIP2 ARL5A DNAJB14 ATP8B1 PHC3 PDP1 RIN2 ZBTB10 WDR44 PTP4A1 ZNF326 PTPN12 PPP2R2A PRIMA1 PROK2 MAP4 ELK3 HBP1 SPRED1 OCLN WASL MTUS1 ROBO2 SP1 GDA PER2 ARHGAP5 NUP160 FAM3C SETD7 SEMA6A KMT2A LPP CRISPLD1 PLD5 NF1 KRAS BMI1 DPY19L3 YAF2 EIF5A2 TTPA PRKAA1 CCDC85A RAB33B FBXO32 LEPR NOTCH4 TMEM106B SLC30A1 LUM PLD1 TBC1D15 SCAF11 UBXN7 TTBK2 FBXO11 AEBP1 TNC UGCG ABI2 PPIL4 LATS1 GATA6 LATS2 UGDH LEPROTL1 GPC4 ADGRG6 MTMR9 QKI CBLL1 CNOT4 ZNF280C FGD6 LRIG2 PDZD2 DLC1 SKIL HIVEP1 MAOB PGAP1 LANCL1 SLK UBN2 FAT4 VGLL3 HEG1 MANEA TROVE2 AEBP2 GXYLT1 TRPC1 CLDN12 KDM5B ZC3H6 JMY CPAMD8 SERTAD4 LIMS1 PDE10A CAMSAP2 KAT6A TMTC3 MTMR12 TMEM2 KMT2E FOXN2 EVI5 PIAS2 OTUD4 CDK14 CPEB3 FBXL20 PPP1R2 SLIT2 PRG4 NADK2 6-MAR ZNF281 FAM126B SMNDC1 RASSF9 FRAS1 FOXJ3 SGCB DOCK4 PCMTD1 RNF138 G2E3 PPM1E BDH2 TTC33 FMOD SLIT3 NDNF GAB1 ARHGAP42 LDLRAD3 BPTF NHLRC2 SLC17A5 GTF2A1 SAV1 PDS5B LYPD6B FAM63B ATP2B4 HMBOX1 RNF38 SPATA6 RORA TNXB GABRA2 PTGIS LDB2 CDC73 SLC2A13 FCHO2 TWSG1 REEP3 ZDHHC2 BIVM SPOPL HECTD2 PPP2R5E SREK1IP1 SLC44A1 LRP12 PLEKHA3 MAPK1IP1L NIPA1 PREPL TAOK1 HOXA4 ADNP FAM120C FBXO30 PAFAH1B1 KIF2A KCNT2 TSHZ3 OPCML WASF3 PIEZO2 TMED8 ATXN7 ODF2L DUSP3 SNX27 FUT11 MMP16 DCHS2 PHEX CACHD1 CLASP1 LEKR1 MAML2 FAM19A2 MFSD4 ZNF333 LRCH2 ASPN C1QTNF7 FAM124B WIPF2 ARL6 RFX8 ADGRL4 KIAA0355 PRELP ZC2HC1A CBFA2T2 TMEM26 DPP6 FAM162B TMEM17 GATA5 FNDC1 EPHA5 LOC101671862 LOC106006686 LOC101687369 LOC101691437 LOC101694623 LOC101677709 LOC106003323 LOC101682876 LOC101687368 LOC101679587 PAPD4 LOC101676402 LOC106006213 LOC101678424 LOC101674285 LOC101692572 LOC101670318 ASPA LOC101670871 LOC101688667 LOC101676955 LOC106003300 LOC101694147 LOC101680580 LOC101683238 QRFPR LOC106003380 LOC101687067 LOC106004477 LOC101674836 LOC106004336 LOC106005009 LOC101677075 LOC101672123 PRUNE LOC101677837 LOC101694602 Top 500 up genes for SARS-CoV-2 infection Day 21 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 GOT1 TIMM10B MVP FBXW5 RPL36 CDH17 TSPO TMUB1 UBXN1 TPM3 PFKL TUBB4B MRPS2 FAM109A PITRM1 GPX1 ACAA1 UBA52 TUBA4A CNDP2 POR FAU TIMM10 CD8A IL17RA AGPAT2 ICAM3 GRB2 GNMT GADD45GIP1 WDR34 MCAT SAC3D1 NAGLU ENO1 BRF1 NINJ1 RGS2 CRYM SLC2A1 TSTD1 SPINK5 RPL7A AIF1 RPS14 RELT POLG ITGB2 LSP1 MYO1G TMC6 USF1 RIC8A PARVG DPP7 RPS6KA1 AKT1 PLCB2 SPN DOK2 EHBP1L1 TBC1D10C ITGAM TKT HK3 PPP1R12C CAPG MRPL12 DDIT4 LGALS1 ATP6V1F MPND TNFAIP8L2 COMMD9 GALK1 TRPM2 MYDGF GAPDH CLTA PADI2 ALDH4A1 SIGIRR GPR68 SLC2A6 KLF15 CKS1B RPS2 AZIN2 EEF1D ARHGEF16 SLC4A2 WNT3A FPGS UPP1 DVL1 ZMYND15 CYHR1 EME2 SYTL1 LFNG OGFR LRCH4 ZAP70 CD48 PSTPIP1 PGLYRP2 TNFSF14 CTSW HCST DEF6 GZMA CHIT1 CCDC88B ITGB7 CORO1A FAM78A SLAMF9 KCNN4 GLIPR1 COTL1 TNNT2 MYBPC3 PGAM2 CCR1 FOLR2 ALAS2 SLC4A1 S100G GLIPR2 IFI35 CCL19 UBE2L6 GSG1L RPL8 CNN2 AKR1A1 CTBP1 HPCAL1 RNF187 GSTP1 MRFAP1 NDUFA3 RPS19 S100A4 RPS5 RPS21 RPS10 NDUFA13 PSMB6 PRDX5 ARL6IP4 PPP1CA ATP5D DRAP1 RPL18 RPS9 OAZ1 IL3RA RPL18A STUB1 ADRM1 TYROBP RAN TALDO1 ROMO1 HN1 LAPTM5 ERRFI1 NDUFA6 EDF1 HCK NCF4 RASSF5 NDUFA7 PGLS ANK1 LST1 RGS14 CCR8 TNFRSF14 HMHA1 UBE2S MRPL24 LAMTOR2 CIB1 PFDN2 CKB TFPT DPP3 DAP3 NHP2 SDHAF2 PHLDA3 RUVBL1 TUBB6 SEC11C TUFM TMSB10 RPL32 RPL29 CPN1 SRXN1 SURF2 INSIG1 MRGBP ARRDC2 SMIM1 CEMIP BTBD6 CTDP1 NUDCD3 SUSD3 AVIL SMOX GSDMD CCDC78 GCHFR FCRLA BATF3 FES GCAT GRIK4 PAQR6 ABAT MED29 METRNL ASRGL1 LRRC45 LMNB2 MRPS11 CYSRT1 LENG9 MMEL1 ARPC1B HOGA1 TM7SF2 PYGL EIF4A1 COPE CLIC1 TAF10 MTX1 BLVRB TCEB2 PTPN6 RNH1 CBS EGLN3 SEC14L2 P2RY8 ADORA2A PSMC4 GET4 SNF8 TIMM21 TRAPPC5 PILRA NADK NCF2 RGS19 DOK3 FGD3 TRADD ARL2 NAAA TFEB CLPP TNFRSF1B CD82 BDH1 ALAD AUP1 BOLA2B AURKAIP1 CMTM7 CHKB APRT CIRBP ALDH3B1 PLEKHJ1 STK25 DDX54 MTG1 NARFL KCNS3 TBL3 ADCK5 FAM173A SLC16A13 RALY ASNA1 RABEP2 GNPTG NUDT14 SIRT7 AMDHD2 FDXR CAPN10 MBD3 MFSD12 DDX39A PTPN18 ZFAND2B PYCR2 PPP1R14B DAPK3 CCM2 TIMM13 CTPS1 NDUFA11 FDPS ARFRP1 EGLN2 DEAF1 IL6R LRPAP1 DNPEP LIN7B BHLHA15 PGP DHPS MRPS7 STK11 TNFRSF13B ADGRG5 ZBTB17 NR1H3 MRPS26 RBM38 HNRNPAB IFRD2 MRPS34 TMED3 RILPL2 ENO3 PLCG2 MAPK8IP1 NAPRT MRPL23 BCL7C SLC25A38 ORAOV1 PACSIN3 MAPKAPK3 PKDCC DNLZ NTHL1 POLR3K GAMT PWP2 RBFA FADS3 CNP TAF6L ALKBH7 ECI1 NDUFS8 SPAG7 UCKL1 PDLIM4 TMEM161A IDH3G TP53I13 GPR161 TMEM134 WBP1 USP20 HIRIP3 GCDH PEX16 THAP3 LSM10 SYNE3 TMEM120A OGFOD3 DPM2 IMP4 PRPF31 UBAC1 TIMM22 HEMGN EPB42 DOK1 GLTSCR2 E4F1 ABT1 TRABD DUS1L SLC25A6 FAM195A CPSF3L NUDT22 STK19 SPSB2 MESDC2 FBXL14 CSNK1G2 ENGASE SPATA6L LIME1 TRMT61A TMEM191C PPP1R35 MRPL49 SLC25A19 RCL1 KLC3 KAZN 2-MAR OSBPL2 ANKS3 CDPF1 TMEM101 CHCHD5 BCAS4 SLC35C2 PPM1M TMIGD2 NOP9 WBSCR16 FAM58A ZNF653 FLAD1 LOC101683191 LOC101691795 LOC101684595 LOC101675829 LOC101677848 LOC101687773 LOC101680253 LOC101672987 LOC101672794 LOC101693544 LOC101672824 LOC101687145 LOC101682491 LOC106003381 LOC101692727 LOC101681077 LOC106004433 LOC101682503 LOC101684888 LOC101686433 LOC101685649 LOC101694055 LOC101674154 LOC106004464 LOC101683501 LOC101679074 LOC101677588 LOC106005426 LOC101689785 LOC101692534 LOC101675923 LOC106004259 RPS7_1 LOC106003683 LOC101689877 LOC101678542 LOC106004248 LOC101678474 LOC101681506 ENTHD2 LOC101682410 LOC101670624 LOC106003865 LOC101688388 LOC101669906 LOC101675405 LOC106003741 LOC101671355 LOC101689620 LOC106005645 LOC101693584 LOC106003335 LOC101683217 LOC106003671 LOC106004696 CALML6 LOC106005611 LOC101692051 LOC106006628 LOC101676720 LOC106005839 LOC106005183 LOC106004787 LOC101686023 LOC101680359 LOC101676309 LOC106005302 MAG LOC106007403 LOC101672667 LOC106004761 LOC101687847 RS1 LOC101675152 LOC101685508 LOC101682893 CFAP58 Top 500 down genes for SARS-CoV-2 infection Day 21 in ferret right caudal lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 PTPN14 ATE1 FKBP1A KPNB1 PTPN21 ASAP2 MYO1D CACNA1D MAST4 XPNPEP2 ETV1 EPS15 BRAF PMEPA1 ENPEP RAB14 FN1 ACE NR3C2 FBN1 ELK4 HS2ST1 FRMD3 DIAPH1 GSK3B DCAF7 UBQLN2 LNPEP ERC1 GPHN ATXN2 NR3C1 FBXO8 KLF12 KDR SF1 CPT1A MED14 NCOA5 SH3D19 SRGAP1 NEBL ZNF532 BEND7 ECM1 PARD6B SH3RF1 COBLL1 TEAD1 PBX1 NFIB RNF152 KIAA1217 PEAK1 PLCE1 QSER1 TJP1 PLEKHG1 NFIA ZBTB20 ZNF462 ARID5B THBS1 LEPROT CYFIP1 NREP ZNF366 ARHGAP29 CTNND1 ITGA1 CARD6 LAMC1 NCAPH OLFML2A CDC42BPA RAPH1 SGCD PTCH1 SPON1 NCALD COLGALT2 AKAP12 TSPYL1 TGFBR3 CDS2 ZFP36L1 TRAK2 KLF11 TGFBR2 APLP2 TRAK1 FGFR1 FOXO1 CSNK1G1 DSP WIF1 LRP6 COL1A2 EREG PRICKLE2 SOX7 ABI3BP NAV2 NR2F2 WNT2 PNN TCF7L2 SLC8A1 BTRC RERE TAB3 HSD11B1 KCNJ3 CHL1 COL3A1 AAK1 ANGPTL4 EPHX1 MAMDC2 ITGA8 ANGPTL2 DPYSL2 CLIC4 THBD PTGES3 EPAS1 RASGRP3 TMCC3 TXNIP SPARC BGN TSPAN7 CTGF NPNT PDGFRA OGN SPECC1L LIMCH1 PDE5A NR1D2 DDR2 PLXDC2 RBMS3 WNK1 FNDC3B FSTL1 NRP1 CTDSP2 IGFBP5 VCL COL6A3 CREB5 GLI3 ADAMTS17 AMER2 AOC3 ISM1 LDB3 MYCT1 CCND2 SULT1E1 SGIP1 CELF2 INSR KLHL15 SERTAD2 SLC29A1 MCUR1 TIMP2 SEC24B KIAA0430 SOSTDC1 SLCO2A1 PLEKHH2 TNFRSF19 KLF7 MN1 SETD2 MBD5 KDM3B KLF3 MAP2 HIVEP2 CDH6 GXYLT2 TMEM200A PCDH9 PLCB1 PSD3 PPP3R1 CD38 NID1 CASS4 TEX14 AFAP1L2 BMPER GPR63 NEB GLG1 CBX5 SPAG9 PRRC2C ZBED6 TNRC6B TULP4 IGF1R RFWD3 DGKH PRRC1 RBMS2 EIF1 EIF4G2 NAV1 CDON CACNB2 FLI1 FRY PAG1 HHIP LAMA3 MMP2 SLC26A7 DPYSL3 SPRY4 ITGA9 PRTG PRKG1 SV2C PUM1 MTSS1 ITGA6 RAD21 UBE2H CTCF TNKS CDK6 RECK SPEN ROS1 SPRY1 TIMP3 NEDD4 ATP2A2 NR2C2 FAF2 PRKCA DENND2A ZC3H11A XPNPEP3 ASAP1 RIN2 PTP4A1 FILIP1 FAT1 PODXL MAP4 ELK3 DKK3 ABLIM3 ARHGEF15 ANKRD17 WASL ZFHX3 MTUS1 ROBO2 SP1 GDA NUP160 GANC FAM13C CHD8 USP9X SETD7 SEMA6A KDM6A NCOA2 KMT2A LPP KMT2C PLD5 RALGAPA2 HECTD4 NF1 ASXL1 DPY19L3 SPRED2 PROX1 EPG5 FBXO32 MAP1A DROSHA LEPR SLC30A1 LUM PDCD6IP LTBP1 HUWE1 TTBK2 RALGAPB LAMA4 NCOA1 EYA3 ABI2 LATS1 GATA6 LATS2 UGDH ANTXR1 SMC1A TPGS2 LEPROTL1 TIAL1 NEMP1 RTF1 GPC4 TCAF1 SCAF4 SETDB1 FOXJ2 TANC2 ATF7 CNOT4 GAPVD1 ARHGAP17 RNF111 USP31 FGD6 MED13L LRIG2 SMG7 PDZD2 DLC1 HIVEP1 REV3L PGAP1 ARHGEF6 UBN2 FAT4 PPP1R3C VGLL3 HEG1 CD109 EIF4EBP2 KDM5B GFRA1 JMY ARHGAP21 HGSNAT FRS2 ATRN MKL2 IDS EPHA3 ASXL2 CAMSAP2 MTMR12 TMEM2 RPRD2 KMT2E CREB3L2 SOS1 PALLD MAPRE2 CPEB3 CPEB4 FBXL20 SYNPO2 SLIT2 FAM168A ERLIN2 6-MAR WDR26 SIN3A SMNDC1 USP37 RASSF9 ADCY9 AP2B1 FOXJ3 SVEP1 SGCB PPM1E FMOD ACACB SLIT3 COL15A1 FBXL7 ITIH5 FAM219A NDNF ARHGAP42 MOB3B ZNF652 LDLRAD3 BPTF CNNM2 PROSER1 PDS5B ATP2B4 HMBOX1 RNF38 HELB SPATA6 UBE4B AFF1 GABRA2 PPP1R12B FCHO2 YLPM1 PPP2R5E MAPK1IP1L TAOK1 FAT3 KIAA2018 ADNP SLC35B4 NPAT FAM120C FBXO30 AKAP6 PAFAH1B1 KCNT2 ZNF385D TSHZ3 IKZF4 GUCY1A2 CACNA2D1 OPCML FAM178A WASF3 PIEZO2 TMOD2 TMED8 ATXN7 GPC6 COL6A5 DUSP3 ICK R3HDM1 MTMR10 MMP16 ACVR2B DCHS2 TBX4 PHEX CACHD1 CLASP1 PTPRG MAML2 FREM1 MFSD4 SNED1 LRCH2 ASPN C1QTNF7 PDZRN4 PDZRN4 SIMC1 WIPF2 ADGRL4 KIAA0355 VGLL4 PRELP ZC2HC1A GRIA3 CBFA2T2 GLTSCR1L TMEM26 C7 FNDC1 EPHA5 LOC101671862 LOC106006686 LOC101687369 LOC101672536 LOC106003323 LOC101679698 LOC101682876 LOC101687368 LOC101679587 LOC101676402 LOC106006213 LOC101674285 LOC101692572 ASPA LOC101688444 LOC101670390 QRFPR LOC101677075 LOC101677359 LOC101677006 ARIH1 LOC101676231 LOC106007030 LOC101679871 LOC101675165 LOC101678603 LOC101694323 LOC106005816 LOC106003903 LOC106003357 Top 500 up genes for SARS-CoV-2 infection Day 2 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 SRP19 TIMM8B CCL5 CISD3 CDH17 RIPK1 CCND3 TLR4 SWI5 UBXN1 TPM3 TUBB4B LAP3 STOML2 IFNG TREM2 ACAA1 UBA52 FBL TUBA4A TRIM25 MRPS25 B2M IL12RB1 CD8A ISG15 SRC ARF6 MBL2 FKBP1B ICAM3 CASP3 GGH MYD88 GRB2 SEPHS2 TMBIM4 DALRD3 NXT2 ENY2 BCL2A1 PSMA2 ATP6V1G1 IGSF6 NDUFB2 RPS25 RPL19 CD2BP2 USF1 RPS6KA1 AKT1 LRRC25 ZDHHC7 QSOX1 SPN SRSF9 EHBP1L1 SLC15A3 TBC1D10C TKT FBXO6 SLITRK4 NDUFB5 CEBPA SLC35A5 GLRX POMP DEPDC1B MSR1 FKBP5 FUCA2 CAPNS1 CTSZ BCAT1 ADORA3 MYDGF SNX3 PADI2 CENPW PRELID1 CLEC12A MRPL51 CCR3 CD247 HRH4 GADD45G MARS CKS1B MMP1 MMP11 BATF JMJD6 SLC7A5 DKK1 IRF8 HNRNPH2 PSMA3 RSAD2 CD69 SIT1 CFB PSTPIP1 RINL SH2D1A TAP1 GZMA IFIT1 FAM78A LY86 CLEC7A COTL1 KIAA0101 CTSS FABP3 DNPH1 SFT2D1 PSMB8 DHX58 CMPK2 ARL11 SNCA PLAC8 TIMELESS UNG NMRAL1 FGG TNFRSF12A PARP12 HSH2D SELP SOCS1 SAMHD1 UBE2L6 CTHRC1 RBP7 PSME1 PSME2 CNN2 PSMB10 CTBP1 SGK1 TXN GLTP PSMB9 RPS19 BCAP31 SNRPD2 RPS5 ACAT2 EIF3K NDUFA13 PSMB6 ARL6IP4 DRAP1 MRPL20 ATP5H NDUFB3 SHFM1 BNIP3 SRP14 IL3RA FDX1 RAN HN1 MPC2 MYEOV2 PSMA6 RPL36AL HCK NOP10 CD36 NDUFC2 CHCHD1 DBI RPS27L OAT TMED2 CD9 TMEM147 CLEC2B SAMSN1 FGB IL27 TMEM258 DPY30 ZBTB8OS UBE2M MRPL46 PSMA4 ASNSD1 CIB1 NDUFAB1 MRPL27 SLC25A11 RPA2 PSMB3 MAGOH MRPL2 RNF151 SDHAF2 GSKIP EMG1 NDUFA12 PTMA DKC1 FAM96A ZNF593 SSB ETHE1 TMEM251 POP5 ELOVL7 PSMA7 PNPT1 GMNN DCTN6 TUBB6 ERH TMEM50A TUFM SNX10 GNL2 SNRPE NARS MAD2L2 IER3IP1 CDK4 AGPAT5 CPN1 SYT13 ANKRD1 SRXN1 PGM1 HDGF ARRDC2 RNF25 CEMIP TRIAP1 SLIRP PIGW SUSD3 MYOZ1 GCA MB21D1 BID GPR18 SPIB HSCB DLST NUDT1 TMEM126B DCTD ALYREF IDH2 SLC25A28 STARD4 LGALS9 CASP7 WSB2 GJB2 ORC6 NFE2L3 PMAIP1 ERAP2 MOB3C CBR3 FAS OPTN SERF2 MSRB1 TAF10 SERP1 CDA SNRPB2 RPL36A SEC14L2 BHLHE22 TUBB3 ADORA2A NCF1 PGK1 PSMC4 TERF2IP NUBP1 PSMD9 SNRPD3 RAB35 SEC13 EXOSC1 LYL1 OSTF1 RET PRMT1 YARS CLPP TNFRSF1B ERP29 STX4 PPP4C GPN3 ZNRD1 TMEM165 IFT20 HAGH TOMM22 PSMC3 CYTH1 SPP1 AURKAIP1 BTBD1 CMTM7 CHKB LTB4R JMJD4 ORAI3 ST3GAL5 AVEN NIP7 NIPA2 FGA ADI1 TRAPPC6A SLC39A13 THOC6 FBXO10 DDX39A MFNG BRD9 UROD WDR74 ERCC1 DHX33 DEAF1 DNPEP CLPTM1L KEAP1 CDC34 OSTM1 NT5C3B MGAT2 GSR ORMDL1 RAB32 PHF23 NXPH3 RNFT1 MRPS7 EMC6 CTBS GPR82 PSMG1 HAX1 AIFM2 PPIF PSMA5 RRP36 RCC2 LSM4 HNRNPAB RRS1 ENDOG MAP2K2 TMED3 RILPL2 DUSP12 TUSC2 ACSF2 MRPL23 RMI2 SDHC MSL3 PDDC1 AEN CSPG5 TRAPPC2L DNLZ GAMT RNF122 CEBPG CNP PBDC1 GPATCH4 NLE1 SPAG7 CIB2 ATP5G1 PFKP RPF2 SNRPD1 HMCES HIGD1A EIF6 DBNL SPCS2 ECI2 EHD3 FBXL15 SHC4 DNAJC12 GALNT15 LSM6 NUS1 MINOS1 SNAP23 FTSJ3 FAM213B METTL1 CD3EAP RHAG MRPS28 WDR61 TIMM22 MRPS24 GLTSCR2 DXO FDX1L EMC8 PSPH ASPHD2 ZGPAT SART1 WBSCR22 PTRH2 CSNK1G2 DTNBP1 YRDC SURF1 XRCC6BP1 MED28 OVCA2 NUGGC ZFYVE19 SASS6 ZNRF1 AP4M1 SNAPC5 SAYSD1 FAM58A RHBDL2 NPRL2 LOC101683191 LOC101691795 LOC101677272 LOC101684595 LOC101684101 LOC101689258 LOC101669908 LOC101670985 LOC101672794 LOC101686692 LOC101679966 LOC101682503 LOC101692710 LOC106004464 LOC106004638 LOC101683501 LOC101675755 LOC101677139 LOC101677791 LOC101692534 LOC101692362 LOC101669892 LOC101672667 LOC101690643 LOC106006622 LOC101685120 LOC101673648 LOC101693790 LOC101676849 LOC101679257 LOC106006399 LOC101681118 LOC101682597 LOC106004724 LOC106003691 LOC101669993 LOC106003851 LOC101672021 LOC101690488 LOC101684235 LOC101684324 LOC101686054 LOC106003630 LOC101682432 LOC101690186 LOC101682694 LOC101691921 LOC101694133 LOC101685657 LOC101681532 LOC101693652 LOC106005408 LOC101688616 LOC101692778 LOC106003364 LOC101680692 LOC101677792 LOC106004898 LOC101677477 LOC101693300 Top 500 down genes for SARS-CoV-2 infection Day 2 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 RNF133 PTBP2 MACF1 DAAM1 EPB41 CACNA1D MAST4 ETV1 BRAF ATM NR3C2 PDE4D ISYNA1 MYCBP2 USP54 GSK3B GOLGB1 PTPN4 AGBL3 ATXN2 KLF12 VPS13B MED14 IFT122 NBEA PCLO POU5F2 FGF14 THRB ALMS1 NFAT5 FOXP2 NFIB HUNK FAM83B TET2 SETBP1 UTRN SORBS2 NFIA ZBTB20 CFAP47 ITGA1 LAMC1 CDC42BPA RAPH1 KCNMA1 SGCD PTCH1 LAMA2 ABCC8 PLCXD3 TRAK1 AR BCAS3 LRP6 LEF1 ABI3BP NAV2 STIM2 WNT2 CCDC170 ATAT1 SCP2D1 BTRC ELP4 GRID1 KIF13B CHRM2 GFPT2 ANGPTL4 GDF10 ANGPTL2 SCN7A PLTP BGN RAPGEF2 SPECC1L PLXDC2 NRP1 RGS5 VCL COL6A3 NOVA1 DMD CREB5 NTRK3 STARD9 ASXL3 DNAH1 SULT1E1 EGFLAM HMCN1 SGIP1 ZNF292 SLC25A27 KANSL1 PAN3 UGT8 LAMB1 SEC24B TNFRSF19 KLF7 BLID SETD2 MBD5 PTPRD CDH6 TMEM200A PCDH9 PLCB1 ZNF671 PSD3 PKD2L1 ITGA11 ADAMTS6 NID1 FNBP4 GPRASP1 THSD7A APCDD1 LONRF2 NEB ORC4 CBX5 SPAG9 NIPBL ZBED6 IGF1R PNISR THOC2 DGKH SON ZNF280D BMF KBTBD3 FRY RBM12 CLK1 RNF148 P2RX5 HHIP CSPG4 COL12A1 MMP2 SLC26A7 GPR21 DPYSL3 TSPAN11 PRTG CXCL12 GPR52 CCSER1 KLHL14 CATSPERB ITGA6 SUPT20H MDM4 SOX5 TNKS ARRB1 NEDD4 NR2C2 FAF2 EXOC2 ZMYM4 DENND2A CALCOCO1 ZC3H11A RPGR PHC3 HELZ ZNF326 FILIP1 CCNT2 PPP2R2A PAPLN SYNE1 FAT1 EML5 SYNE2 BCL6 TENM1 AMOTL1 MICAL3 DST PDGFRB SREK1 ANKRD17 DGKG ROBO2 SP1 ZBED5 LCORL GANC KDM3A SETD7 FOXP1 KDM6A NCOA2 KMT2A LPP KMT2C NRXN1 PLD5 DNAH8 TTC6 RALGAPA2 HECTD4 NF1 UNC5C RUNX1T1 SETD5 PCM1 CHD2 BCL2L11 NOTCH3 PROX1 CACNA1C TP53BP1 PCDH17 EPG5 FBXO32 DROSHA UBR5 PRKDC APOA1 ZNF800 NCAM1 LTBP1 DNAH9 TTBK2 RALGAPB PARP4 FBXO11 RFX3 CBLB ANTXR1 SMC1A TIAL1 GPC4 TANC2 CNOT4 INO80 FGD6 MLLT10 KDM5C LRIG2 CLK4 HIVEP1 RPGRIP1L MYSM1 REV3L DZIP3 UBN2 FAT4 EIF4EBP2 KDM5B ANK2 PDE3A ARHGAP21 PTPRK PHF20L1 ZCCHC14 USP6NL BICC1 TNRC6A 7-MAR RPRD2 KMT2E RALGAPA1 BAZ2B CREB3L2 SOS1 PIAS2 PALLD SCAI BRWD1 IRGQ MED12L CFAP54 FRYL CCDC171 FBXL20 LMLN ZKSCAN2 SLIT2 FAM168A ARHGEF9 RELN SLC7A2 HAL ZFC3H1 CHD9 EPM2AIP1 SVEP1 DOCK4 PPM1E SLC4A8 ADGRL3 LAYN FMOD SLIT3 NGFR HMCN2 SESTD1 NDNF GAB1 ARHGAP42 MOB3B RBM45 NHSL1 ITPR2 SRRM1 BPTF NKTR CNNM2 BRWD3 PDS5B KIAA1109 ATP2B4 HMBOX1 NR6A1 SPATA6 CSPP1 MSS51 ULK4 ATL2 FER CDKL2 ADNP NPAT FAM120C AKAP6 ELMO1 GUCY1A2 CACNA2D1 KAT6B TMOD2 TMED8 GPR158 NBEAL1 ICK THBS4 RBM26 PPP1R32 DPH6 WDR66 BRD8 AGO3 ST8SIA1 MMP16 ACVR2B THADA PHF14 LARP1B PCDH18 DCHS2 STXBP4 CACHD1 KATNAL1 SCN8A CLASP1 ALG13 MAML2 AMHR2 FREM1 SNED1 DIS3L2 ADAMTSL1 BBS9 C1QTNF7 PDZRN4 PDZRN4 ZCCHC11 CATSPER2 WIPF3 RAD51B ADGRV1 LRCH3 PRELP POLK RALYL DNAH3 PCNXL4 HKR1 AHI1 FAM175A KIAA0825 RIMBP2 RPA4 FNDC1 DHX57 ERMARD LOC101691570 LOC106003850 LOC106003350 LOC101671834 LOC106003800 LOC101682202 LOC106003319 LOC106005762 LOC106004738 LOC101672982 LOC101686871 LOC106005784 LOC106004539 LOC101684740 LOC106003548 LOC101687369 LOC101686272 LOC106006873 LOC106003877 LOC106003788 LOC101689178 LOC106004537 LOC101672536 PURG LOC106007196 LOC106005041 LOC101681919 LOC106003946 LOC106003721 LOC106003730 LOC101691437 LOC101676209 LOC101684148 LOC106006942 LOC101670772 LOC106005312 LOC106005394 LOC101687351 LOC101690273 LOC101693847 LOC106006347 LOC101673799 LOC101677652 LOC101694604 LOC106003323 LOC101692993 LOC106005444 LOC106004099 LOC106007124 LOC101681735 LOC101679587 LOC101680703 LOC101689246 LOC101678424 LOC101674285 LOC101670318 ASPA LOC106003787 LOC101688444 LOC101688667 LOC101676955 LOC101674734 LOC101683238 LOC106006044 LOC101677006 LOC106007153 LOC106003975 LOC101670167 LOC106007161 LOC101674053 LOC101681950 GJA10 LOC106005827 LOC106004175 LOC106007155 LOC106004524 LOC101690145 LOC101690546 LOC106003710 LOC101675110 LOC106003969 LOC106006533 LOC106004182 LOC101675761 LOC106007029 LOC106007200 LOC101690486 LOC106003284 LOC101676467 LOC101679172 CCDC168 LOC101671576 LOC106006576 WHSC1L1 KIAA1468 LOC101683901 GRIA4 LOC106006961 LOC101686662 LOC101671345 LOC106004312 LOC101694254 CFAP61 LOC106006514 LOC101687611 LOC106003533 LOC101678468 Top 500 up genes for SARS-CoV-2 infection Day 7 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 NDFIP2 DCTPP1 PDCD1 VHL NPC2 ACE2 TLR4 SWI5 TPM3 TMEM97 CRYL1 LAP3 ACSL3 IFNG GPX1 TREM2 ACAA1 PLS1 TUBA4A STAT1 CNDP2 IL12RB1 TMEM173 PLD3 VSIG4 ARF6 FBP1 MBL2 ICAM3 CSF2 GGH PIGU MYD88 GRB2 SEPHS2 TMBIM4 MGAT1 BCL2A1 MCL1 ATP6V1G1 ENO1 CDK2AP1 PIGR NDUFB2 KLHDC9 TPST1 AIF1 FTL CD2BP2 ITGB2 MYO1G USF1 TRPV2 C1QA RPS6KA1 LRRC25 DDRGK1 SPN DOK2 SLC15A3 TBC1D10C ACLY CAPG SLC35A5 GLRX PSEN2 DEPDC1B BUB1B TNFRSF17 ATP6V1F FUCA2 MZB1 TMEM150B BUB1 BCAT1 TNFAIP8L2 ADORA3 SCIMP TP53I3 GAPDH CLTA PTPRO CENPW JCHAIN PRELID1 CLEC12A CD247 GPR68 MATK HRH4 IL18RAP CKS1B BATF HPGDS SLC7A5 CXCL13 CLU TMEM60 IRF8 NUCB2 CBFB HCLS1 ZAP70 CD48 CD69 CENPA CFB PSTPIP1 ZBP1 RINL CKAP2L TAP1 TLR1 CLEC5A GZMA ERCC6L CD72 CORO1A FAM78A TNIP3 CCR5 LY86 CLEC7A GLIPR1 COTL1 KIAA0101 CTSS PTPN7 ADIPOQ RETN FABP3 MYBPHL MYBPC3 MYL4 PSAT1 CD86 CCR1 FOLR2 IL1RN EVI2A OSCAR TIMELESS FGG TCIRG1 TNFRSF12A GLIPR2 HSH2D IL4I1 SOCS1 CCL19 GPR34 PSME2 CNN2 PSMB10 ELOVL5 TXN ATP6V0E1 GLTP PSMB9 RPS19 SFTPC MDH2 ACAT2 ARL6IP4 SLC12A2 PTP4A2 SRP14 RPS9 IL3RA FDX1 TYROBP NDUFA2 IFI30 HN1 LAPTM5 HCK NCF4 SAT1 CD36 OAT BEX4 CD9 PGLS CLEC2B SAMSN1 FGB IL27 P2RY12 KCNN2 GPR157 MOB1A ZBTB8OS MRPL46 CIB1 M6PR SRM PTTG1 SRP9 TIPIN DPP3 VMP1 SDHAF2 GSKIP PTMA FAM96A ZNF593 ETHE1 TUBB6 SNX10 GNL2 NDUFA9 RPL29 IER3IP1 CPN1 HSD17B11 SGMS2 ADORA2B SYT13 KRCC1 PGM1 MAGOHB TRIAP1 GMDS PIGW CCDC94 TLR2 IL15RA MB21D1 BID TIMD4 POU2AF1 GCHFR FCRLA NCKAP1L WAS BATF3 DGAT2 GPR18 TFRC FCAMR CXCL11 NUDT1 RP2 IFI6 LY96 IL32 SIGLEC10 C6 ALYREF DNA2 STARD4 CKAP4 PSTPIP2 GJB2 HOXA6 ARPC1B MOB3C FAS OPTN RNF149 EIF4A1 PTPN6 SERPINB1 SERP1 CDA KCNE3 PPTC7 IL1RAP SEC14L2 BHLHE22 MLIP SLC17A9 P2RY8 ADORA2A NCF1 CD80 ACP5 PGK1 PSMC4 C4A RTCA CLECL1 PILRA OSTF1 YARS TNFRSF1B PLEKHB2 ADPGK PPP4C FKBP11 LACTB ZNRD1 BDH1 RFK TMEM183A GALNT1 MCFD2 CMPK1 AURKAIP1 CMTM3 CMTM7 CHKB ACAT1 ALDH3B1 GGCT ORAI3 NIP7 TRMT2B FAM49B FGA MZT2B SLC39A13 CAPN10 DDX39A GMFG RGS18 ILVBL RAB27A TSPAN15 BHLHA15 RAB32 NXPH3 CISD2 DHPS MRPS7 SEMA4A CTBS MTHFD1 GPR82 HSD17B13 PPIF PSMA5 RCC2 HNRNPAB ENDOG TUSC2 ENO3 RMI2 PDDC1 SLC25A38 MAPKAPK3 DNLZ PFKFB2 SSX2IP CNP PBDC1 KIAA1191 CIB2 PDLIM4 DCAF11 PFKP GOLIM4 MYCBP SVIP HIGD1A CENPQ SPCS2 VWA5A GCDH ECI2 PRKCB MFAP3L ATP13A5 ALDH18A1 RABGGTB PTPMT1 PLLP CR1L EMC8 ASPHD2 COQ7 SCYL2 DYRK4 FMN2 HTR7 MIIP CCNB3 SURF1 MED28 NSMCE2 GINS3 OVCA2 NUGGC RNF170 TOMM40L TMEM18 SASS6 UNC119 QTRTD1 TMEM101 BPIFC NPRL2 LOC101684595 LOC101679687 LOC101675829 LOC101693479 LOC101693963 LOC106004811 LOC106004684 LOC101677848 LOC101684101 LOC101680253 LOC101672987 LOC101672794 LOC101671409 LOC101687145 LOC101692293 LOC106003421 ARL5C LOC101679372 LOC101686692 LOC101692727 LOC101692737 LOC101686302 LOC101682503 LOC101680794 LOC101685649 LOC101693539 LOC106004464 LOC106004638 LOC101690652 LOC101677139 LOC101692534 LOC101691890 LOC101693046 LOC101686007 LOC106003865 LOC101680639 LOC101676319 LOC101680350 LOC101684720 LOC106003335 LOC101692463 LOC101692051 LOC101672667 LOC101685120 LOC106006399 LOC101681118 LOC101690488 LOC101684324 LOC101685657 LOC101681532 LOC101692778 LOC101677792 LOC101672135 LOC101685623 LOC106003941 LOC101692175 LOC101683447 LOC101691243 LOC101675044 KLHL35 LOC101683420 LOC101684716 LOC106004430 LOC101677807 LOC106005629 AADACL3 LOC106005849 LOC101686497 LOC101680710 LOC106006356 LOC106003500 LOC101676822 LOC101675033 LOC101686012 LOC101676332 LOC101677176 LOC101689267 ARMC12 LOC101681174 LOC106003515 LOC106005466 PTX4 LOC106006940 LOC101687304 LOC106004037 LOC101691518 LOC106003280 LOC106004276 LOC106005095 LOC101686202 LOC106004753 LOC106005231 LOC106004817 LOC106007317 LOC101683484 LOC106007251 STK26 LOC101679324 LOC106007341 LOC106007406 LOC101689439 LOC106005385 LOC101694702 LOC106006093 LOC101679196 LOC106004802 LOC101670046 LOC106004057 Top 500 down genes for SARS-CoV-2 infection Day 7 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 SPTB PTPN14 CAPN5 RNF133 CD34 APLNR FRMD7 ASAP2 DAAM1 EPB41 CACNA1D IL17RD MAST4 XPNPEP2 BRAF SPTA1 EHBP1 RYBP FLT1 TP53 FN1 NCKAP5 NR3C2 ISYNA1 FBN1 USP54 PCSK6 GSK3B UBQLN2 KALRN SPTBN1 GPHN SLC25A39 SMO ATXN2 KLF12 ARL4D PCLO SH3D19 PARVA MCF2L SRGAP1 NEBL ZNF532 BEND7 SLC40A1 HLF RAI14 FOXP2 PEAK1 HUNK FAM83B PLCE1 USP51 SETBP1 UTRN SORBS2 PSCA AGAP1 PLEKHG1 NFIA ZBTB20 THBS1 AREG ACCS LAMC1 ADAMTS2 GRB10 OLFML2A CDC42BPA RAPH1 KCNMA1 LTBP4 SGCD PTCH1 AKT3 LAMA2 PTPRS TGFBR3 NUAK1 ABCC8 ZFP36L1 APLP1 TRAK2 KLF11 PKD1 AXL FGFR1 DSP BCAS3 JUP MYO19 NKD1 COL1A2 LEF1 PRICKLE2 SOX7 ABI3BP NAV2 FGF1 NR2F2 TCF7 STIM2 DIXDC1 WNT2 CACNA1H GLI2 BTRC KIF13B KCNJ3 CHL1 ZRANB3 CHRM2 RAMP1 KL ANGPTL4 ANGPTL2 ZNF704 EPAS1 PLTP THRA TPPP3 RAMP2 CDC42EP1 BGN RAPGEF2 AGER PDGFRA SPECC1L LIMCH1 MYH10 BCL6B DNAJC8 DDR2 PLXDC2 FHL1 ESAM LIMS2 TCF4 VWF PHLDB2 NRP1 USHBP1 VCL CREB5 TSPAN18 NTRK3 GLI3 ADAMTS17 STARD9 AOC3 LHX6 WSCD1 CCND2 SULT1E1 HMCN1 ZSCAN9 PPAP2B ROBO4 KANSL1 TIMP2 LAMB1 SEC24B FOXF2 SLCO2A1 PLEKHH2 TNFRSF19 KLF7 MN1 ZCCHC24 MAP2 HIVEP2 VEGFC TMEM200A PCDH9 PLCB1 ZNF671 STXBP1 PSD3 MFAP4 ROR2 NALCN NEU3 SLC1A4 NID1 FAM171A1 RBBP5 AHNAK2 NPR2 SPAG9 NIPBL SMURF2 IGF1R SEMA3G DGKH IRS1 EIF1 NAV1 CDON BMF SALL2 CACNB2 CDC42EP2 DAPK2 GREM2 RNF148 DNM1 P2RX5 PAMR1 ADAMTS9 ZFP57 TSPAN11 PRTG MEGF10 CXCL12 SV2C KLHL14 CACNA1E PIAS3 BACE1 SPEN TIMP3 CA12 FAIM2 ARRB1 FAF2 TARSL2 VTN DENND2A ZC3H11A ABHD4 TPCN1 MPP3 RAB3IL1 RIN2 HELZ SPINK4 ZNF8 MTA3 DLL4 OBSL1 MEGF6 PAPLN FAT1 ENG EML5 SYNE2 EIF1B MAP4 AMOTL1 MICAL3 DST PDGFRB PLXNA2 ABLIM3 FLNC PCDH1 RBFOX2 ANKRD17 DGKG MTUS1 ROBO2 SP1 GDA DGKI USP9X SETD7 SEMA6A KDM6A NCOA2 PARD3 KMT2A LPP PLD5 ENOX1 NF1 PCM1 NOTCH3 EPG5 FBXO32 MAP1A DROSHA APOA1 PLD1 ZNF630 ZKSCAN8 GPC3 PCYT1B HUWE1 LAMA4 TNC CBLB ABI2 GATA6 ANTXR1 F11R GPC4 TCAF1 PEG10 EIF4ENIF1 CNOT4 INO80 FGD6 LRIG2 PDZD2 DLC1 HIVEP1 MAOB PGAP1 ANKRD50 UBN2 FAT4 HEG1 EIF4EBP2 KDM5B PDE3A KCNK5 ARHGAP21 ICE1 MKL2 PTPRK ZCCHC14 TMEM2 GPATCH8 TRIO RPRD2 KMT2E MYOM1 CREB3L2 PALLD CDK14 MAPRE2 IL1RL2 SIPA1L2 CCDC171 SSPN ZC3H13 TTC28 SLIT2 FAM168A ARHGEF9 HDAC11 SLC7A2 FRAS1 ADCY9 FOXJ3 SVEP1 DOCK4 PPM1E ARHGEF17 SLIT3 TNS2 CAMK1G COL15A1 FBXL7 PRDM6 ADARB1 TIE1 SESTD1 NDNF GAB1 ARHGAP42 BPTF ATP2B4 HMBOX1 HEMGN SPATA6 TNXB GABRA2 LDB2 TBX5 FAT3 ADNP NPAT NR2C1 AKAP6 GUCY1A2 PLXNC1 KAT6B GPR158 GPC6 DUSP3 USP46 RNF157 RIMKLA ICK DEPDC5 CNTFR PLEKHM3 CHN1 KIAA1328 CNR2 GALR1 ACVR2B PCDH18 DCHS2 STXBP4 TBX4 PHEX CLASP1 PTPRG KLHL31 MFSD4 SNED1 WNK3 ZNF521 ADAMTSL1 C1QTNF7 PKNOX2 ADGRA2 EFCC1 INSC INSC ZCCHC11 CATSPER2 SIMC1 LRCH3 PRELP KANK1 HKR1 THAP8 GRAMD3 CCBL2 FAM162B PCDHB15 MUSTN1 FNDC1 GPIHBP1 DHX57 LOC101693895 LOC101671862 LOC106003319 LOC106004738 LOC106004539 LOC106004036 LOC101687369 LOC106003433 LOC106005041 LOC106003721 LOC101691437 LOC101677652 LOC106003323 LOC101682876 LOC106005444 ST8SIA2 LOC106004099 LOC101679587 LOC101680703 LOC101689246 LOC101674285 LOC101670318 LOC101671028 LOC101688444 LOC101688667 LOC101674734 LOC106003300 QRFPR LOC101676723 LOC101692986 LOC101673446 LOC101671813 LOC101687067 LOC101674836 LOC101677075 LOC101694602 LOC101677359 LOC101677006 LOC101670167 LOC101674053 LOC106007155 LOC106003710 LOC101675761 LOC101676467 LOC106006576 LOC101683901 GRIA4 LOC106004312 LOC101678468 LOC101673073 LOC101670731 LOC101691389 LOC101687984 LOC101683527 LOC101688782 LOC101670706 LOC106006839 LOC101678687 LOC101687107 LOC101677197 LOC101693176 LOC106006846 LOC106007374 LOC101688511 LOC101671638 LOC106007424 LOC106007110 LOC106004641 LOC106006935 LOC101677992 LOC106003925 LOC106003978 Top 500 up genes for SARS-CoV-2 infection Day 14 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 GOT1 TEKT3 CDH17 BCKDK ACE2 TLR4 TPM3 TMEM97 PVR LAP3 STOML2 SARS RNF41 TREM2 ACAA1 FBL PSMD4 TUBA4A TSPAN8 CNDP2 ITM2A PHB MEP1A FERMT3 PRKAR2A ARF6 FBP1 FKBP1B UBFD1 PPIA NEU1 GNMT RABEPK BPNT1 NPY PARP16 MGAT1 ENO1 OCIAD2 SNTN BPIFB1 PCP4L1 ARL3 SLC15A2 CRYM LURAP1L CD180 HSPB8 SLC25A4 CKS2 PTN ATOX1 EYA1 ZNF467 RPL19 AIF1 AADAT FTL SRRT MPZL2 PGD LRRC25 DDRGK1 QSOX1 SRSF9 FBXO6 ACLY PYCR1 CEBPA SNX32 GLRX TK2 AURKA TMEM150B CAPNS1 SHMT1 TP53I3 PPARG GAPDH SNX3 CDC20 SYN2 TPI1 PRELID1 PSMB7 NOG NAP1L2 MARS CKS1B RPS2 DMRT2 CISH PLCD1 SLC7A5 SLC45A2 SYNPR GZMA GTSF1 CLEC7A ADIPOQ FABP3 VAT1L PSAT1 CA13 SNCA NMRAL1 S100G FGG TNFRSF12A SOCS1 ARNTL P2RX6 PSME2 CNN2 HMGN1 ELOVL5 HMGCS1 TXN MDH2 ACAT2 PSMB6 ARL6IP4 MRPL20 SLC12A2 NDUFB3 BNIP3 PABPN1 SRP14 STUB1 LAMTOR1 RAN CCT3 ATF4 MRPL28 MYEOV2 RPL36AL SELENBP1 CSF2RA NOP10 DBI OAT CD9 TMEM147 AGPAT4 PGLS GJB7 CLIC2 FGB KCNN2 B3GNT5 AURKC GPR157 SOWAHC MRPL34 UBE2M MRPL46 ASNSD1 CIB1 NDUFAB1 SEC61A1 SRM PGAM1 CKB APOA1BP PSMB3 DPP3 MRPL2 SDHAF2 PIH1D1 DCTN3 HSD17B2 DKC1 ZNF593 ETHE1 POP5 ELOVL7 PSMA7 CCT7 RUVBL1 TUBB6 CBX1 GNL2 NDUFA9 MAD2L2 CDK4 CPN1 NUDT9 HSD17B11 RUVBL2 KHDRBS3 FKBP4 SRXN1 ARFIP2 INSIG1 RRAGC PGM1 MSMO1 FAM46B SQLE CEMIP CDCA7 ELMOD1 HSD17B14 MVD ATP5G2 PPM1K F13A1 GCHFR FCRLA BATF3 GCAT DCPS ABAT ALKBH6 CCDC106 STARD4 CKAP4 WSB2 GJB2 LIPH REEP4 HOXA6 OPTN EIF4A1 CALM2 SLC9C2 CENPV OSGIN1 SEC14L2 BHLHE22 FADS2 KANK4 TMEM95 TACR1 SFTA2 CCDC34 FFAR4 PGK1 PSMC4 SNRPD3 FTSJ1 SEC13 TEN1 CLECL1 NAGK GDF5 YARS IFNGR2 SC5D QARS ADPGK USP5 STX4 COPG2 POLD4 HAGH TOMM22 BDH1 SPP1 AKIRIN1 TMEM183A SMIM12 CMTM7 CHKB ACAT1 ALDH3B1 CNPY2 STK25 ORAI3 ST3GAL5 RPF1 FGA RALY ASNA1 NUDT14 SLC39A13 PRADC1 DDX39A SLC39A7 BAALC FDPS ERCC1 MFSD7 FDFT1 MCCC1 GCLC KEAP1 CMBL NT5C3B MPHOSPH6 ZBTB18 FXYD3 TSPAN15 ARHGEF38 RAB32 PHF23 LRRC59 DHPS IVD MRPS7 SLC19A2 RAB24 MTHFD1 ADGRG5 PSMG1 CIAPIN1 HSD17B13 KLB MTFP1 PPIF PSMA5 RRP36 PRDX6 MSRA TUSC2 MRPL23 DCBLD2 RMI2 ALDH7A1 HSD17B12 SDHC ATP5B PDDC1 SLC25A38 ZBTB24 MRM1 SLC25A37 DHCR7 PXMP2 NSDHL PKDCC MMAB DNLZ MFSD2A KLHL4 PFKFB2 LPCAT3 COL22A1 TBC1D4 PBDC1 RAB27B SLC50A1 KIAA1191 UNC5A DCAF11 ATP5G1 NOCT RPF2 MRPL43 HIGD1A ECHDC1 CENPQ PAIP2B MGST2 SPCS2 GCDH ACADL PCCB ISOC1 CDK5R1 MFAP3L KCNK1 DNAJC12 ATP13A5 RABGGTB FTSJ3 METTL1 IMP4 TIMM22 SMG5 ANKRD2 EMC8 PSPH FAM47E COQ7 FAM195A TTC25 PAQR7 HTR7 TCEA3 SPATA6L GALT ZNF768 SURF1 EDARADD RCL1 TIMM8A NUGGC CCDC27 SPIRE2 SLC35F2 ZFYVE19 TOMM40L GJA9 ZNRF1 QTRTD1 RIC3 PIFO CEBPE PPM1M OSGEP KCNRG SPATS1 FAM177B FLAD1 NPRL2 LOC101682249 LOC101683545 LOC101676573 LOC106004811 LOC101672824 LOC101692727 LOC101677815 LOC101688808 ZSWIM5 LOC101692890 LOC101689447 LOC101679966 LOC101678900 LOC101681864 LOC101676905 LOC101671415 LOC101682503 LOC101693539 LOC101694055 LOC101677588 LOC101677139 LOC101692534 LOC101692362 LOC106003865 LOC101676319 LOC106003335 LOC101683217 LOC101685910 LOC101669892 LOC101692051 LOC106005839 LOC101693790 LOC101676849 LOC101681118 LOC106003851 LOC101672021 LOC101690488 LOC101684324 LOC101691921 LOC101694133 LOC101681532 LOC101692778 LOC101693300 LOC101672135 LOC101685623 LOC101683447 LOC101691243 LOC106004430 LOC106003500 LOC101677176 LOC106003515 LOC101691518 LOC106004276 LOC106007251 LOC106005385 LOC101670046 LOC106004057 LOC106006912 LOC101672478 LOC106004242 LOC101688364 LOC101678894 LOC106007484 LOC101684003 LOC101688357 LOC106007324 LOC101685276 LOC106003558 HYKK LOC101671789 LOC106004808 LOC101679555 LOC101679224 LOC101689455 LOC101690439 LOC101675541 TDRD5 CNTNAP5 LOC106003643 LOC101675684 LOC101688994 LOC101672798 LOC106006808 LOC106004563 LOC101684855 LOC106004249 LOC101688911 LOC106005313 LOC106003624 LOC101688551 LOC101670856 LOC106006871 LOC106006555 LOC101678605 Top 500 down genes for SARS-CoV-2 infection Day 14 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 CUBN COL6A1 CD34 APLNR ASAP2 DAAM1 EPB41 RNF24 CACNA1D MAST4 XPNPEP2 PMEPA1 ENPEP FN1 ACE NR3C2 PDE4D FBN1 EIF2AK2 PCSK6 ELK4 TLN2 FRMD3 GSK3B LNPEP GPHN KLF12 CPT1A SH3D19 MCF2L SRGAP1 POU5F2 TRPS1 ALMS1 SLC4A4 HLF FOXP2 HUNK TET2 SETBP1 PSCA ZBTB20 KSR1 GSN PLEKHO2 SMAD7 ITGA5 NRP2 RHOB LHFPL2 LAMC1 ADAMTS2 OLFML2A MMP19 CDC42BPA ARHGAP23 RAPH1 KCNMA1 GLI1 LTBP4 PTCH1 PTPRS COL6A2 AKAP12 TGFBR3 B4GALT5 CDS2 ZFP36L1 KLF10 COL1A1 KLF11 PIK3IP1 B4GALT6 PKD1 MAPT AMTN FGFR1 FOXO1 AR BCAS3 EPHB4 COL1A2 LEF1 AXIN2 ABI3BP NAV2 FGF1 NR2F2 TCF7 STIM2 FZD4 RSAD2 NLRC5 IRG1 ACKR1 IFIT3 IFIT1B APOL6 COL3A1 HERC6 IGFBP6 KL ANGPTL4 PABPC4L MAMDC2 ANGPTL2 ZNF704 THBD KLF4 EPAS1 IER3 PLTP THRA PLVAP RAMP2 CDC42EP1 BGN GATA2 PTPRB RAPGEF2 CTGF PDGFRA SPECC1L NR1D2 TMEM176B PPP1R14A DDR2 PLXDC2 ITPRIPL2 NPR3 TCF4 VWF KIAA1462 CREB5 TSPAN18 GLI3 ADAMTS17 STARD9 LHX6 CCND2 SULT1E1 EGFLAM HMCN1 SLC35E4 CELF2 HIC1 ROBO4 FLRT3 KANSL1 SLC29A1 TIMP2 SEC24B MXI1 MXD1 SLCO2A1 TNFRSF19 PDE4B KLF7 ID1 MN1 BLID CREBRF ID2 KLF3 MAP2 HIVEP2 PCDH9 CHSY3 ZNF671 STXBP1 PSD3 HFM1 MFAP4 ITGA11 ZCCHC2 CSF3R PDK4 NALCN CD38 NID1 TEX14 THSD7A LONRF2 SPIN4 RNF19B MX2 CBX5 TOP1 TMEM107 NIPBL IGF1R SEMA3G PCDHB5 PKHD1L1 DGKH RCAN1 CHST15 PROCR IRS1 NAV1 CDON RGS17 BMF ATF7IP HEYL KBTBD3 FLI1 PAG1 RNF148 ADAM19 MMP2 NR1D1 SCN2A SPRY4 THSD7B RAMP3 SCN5A ZFP57 TSPAN11 PRTG CXCL12 TAL1 ITGA6 BACE1 RECK TIMP3 CA12 ARRB1 NEDD4 TARSL2 PRKCA NUP153 DENND2A BOC TTC23 FIP1L1 ASAP1 RIN2 FLT4 HELZ THBS3 KCNJ2 ZNF326 PPP2R2A OBSL1 SYNE1 ENG EML5 PODXL SYNE2 WIPF1 TENM1 TANC1 SSH2 MAP4 AMOTL1 HBP1 MICAL3 DST ADCY4 FLNC ARAP3 PRKCE ROBO2 SP1 ZBED5 GDA ABI3 PER2 ECE1 GANC SETD7 GREB1 SEMA6A FOXP1 KDM6A KMT2A LPP PLD5 RALGAPA2 NF1 RUNX1T1 DPY19L3 SYNJ2 KCNAB1 NOTCH3 FBXO32 CARD10 NOTCH4 LUM TUBGCP5 ZKSCAN8 ABTB1 FBXO11 COL5A1 TNC CBLB ABI2 STAT5B NTN1 PODN SLC25A20 TIAL1 GPC4 TCAF1 PEG10 CNOT4 IP6K1 TIAM2 FGD6 LRIG2 PDZD2 HIVEP1 UBE2E3 MAOB PGAP1 VANGL2 UBN2 FAT4 HEG1 KDM5B JMY MKL2 ADNP2 BICC1 KAT6A TMEM2 RPRD2 KMT2E BAZ2B PIAS2 HECW2 PALLD MAPRE2 FBXL20 PRR14L SLIT2 ARHGEF9 HOXA3 MAMLD1 ADCY9 SFMBT2 SVEP1 DOCK4 CCNJL PPM1E SLIT3 TNS2 HMCN2 RASIP1 COL15A1 ITIH5 PRDM6 SLC4A3 ADAMTS7 TIE1 SESTD1 NDNF GAB1 ARHGAP26 PALD1 LDLRAD3 BPTF PHLPP1 ATP2B4 HMBOX1 HELB SPATA6 TNXB GABRA2 PTGIS LDB2 TBX5 FCHO2 SOGA1 MAPK1IP1L FIGN AKAP6 PALM KCNT2 ELMO1 OPCML WASF3 KAT6B TMED8 PCNX ITGBL1 DUSP3 RNF157 RIC1 MTMR10 PLEKHM3 ACVR2B PTPRG LRRC75B MAML2 AMHR2 FREM1 MFSD4 ILDR2 SNED1 SLC30A10 ZNF333 ADGRA2 FAM65A ANKRD24 KIAA0355 PRELP ZC2HC1A TDRD3 PCDHB15 RPA4 FNDC1 LOC101671862 LOC101676601 LOC106005184 LOC106007139 LOC106004738 LOC106004036 LOC101687369 LOC106003788 LOC101672536 LOC101686140 LOC106007196 LOC101691401 LOC106003721 LOC101691437 LOC101673799 LOC101677652 LOC106003323 LOC101682876 LOC101692993 LOC101687368 ST8SIA2 LOC101679587 LOC101679280 LOC101674563 LOC101678424 LOC101674285 LOC101670318 ASPA LOC101671185 LOC101674734 LOC106003300 QRFPR LOC101673446 LOC101674836 LOC101677075 LOC101672123 LOC101694602 LOC101677359 LOC101677006 LOC106007030 LOC106003357 LOC106007153 LOC101670167 LOC101674053 LOC106005827 LOC106003710 LOC106003969 GRIA4 LOC106006961 LOC101694254 LOC101678468 LOC101670706 LOC106006839 LOC101678687 LOC101688511 LOC106007424 LOC106003925 LOC101683862 LOC101676607 LOC101670323 LOC106004016 LOC101687023 LOC101670156 LOC101682617 LOC101677542 LOC106006249 LOC106006404 LOC101680117 LOC101676070 LOC106003658 LOC101680667 LOC101685187 LOC101671838 LOC101689686 LOC106004603 LOC101683557 LOC101671341 LOC106003901 LOC106005706 LOC106004627 LOC106006359 LOC101682805 LOC101684722 LOC101682907 LOC101674428 LOC106007169 LOC101683873 Top 500 up genes for SARS-CoV-2 infection Day 21 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 GOT1 TIMM8B MAPK3 PSMD8 RPL12 ACADM SWI5 NGDN TPM3 TMEM97 RBX1 SCCPDH CRYL1 LAP3 STOML2 SARS ACSL3 RNF41 IFNG CTNNB1 ALG5 ACAA1 FBL PSMD4 TUBA4A ITM2A NEDD8 CD8B PES1 PRKAR2A MBL2 PPIA GRB2 DHTKD1 GNMT RABEPK BPNT1 NPY ENY2 FECH ENO1 TBCB PCP4L1 PERP ARL3 RPS11 RPL27 IGSF6 TSPAN6 HSPB8 SLC25A4 RPL39 RPL19 ABCA1 AIF1 TSPAN3 USF1 EMC10 LRRC25 SRSF9 ACLY LPL GLRX MGST1 POMP KCTD3 DDIT4 FUCA2 CAPNS1 SHMT1 NDUFS4 TP53I3 SNAPIN GAPDH CLTA SNX3 IDH1 PRELID1 PSMB7 NAP1L2 PHOSPHO1 MARS HINT2 ITGA2B PSMA3 PGLYRP2 GZMA RETN FABP3 PSAT1 ALAS2 SLC4A1 S100G FGG MCOLN2 F9 SOCS1 GSG1L PSME2 CNN2 AKR1A1 PSMB10 BAG1 SDHB ELOVL5 PEBP1 HMGCS1 TXN ATP6V0E1 GLTP RPL3 SFTPC VIMP SNRPD2 ACAT2 EIF3K RPN1 PSMB6 ARL6IP4 MRPL20 PSMB5 PFDN6 SLC12A2 QDPR ATP5H NDUFB3 SRP14 PSMB4 STUB1 NDUFA2 LAMTOR1 RAN KRTCAP2 MPC2 ERRFI1 RPL36AL HCK TPRG1L NOP10 EMC2 CHCHD1 DBI OAT PGRMC1 NDUFB10 TMED2 CD9 TMEM147 DAD1 LST1 FGB FBXO40 TENM2 PROC GPR157 TMEM258 NDUFS2 NR2C2AP ATRAID DEPDC7 MRPL34 UBE2M MRPL46 PSMA4 ASNSD1 MSRB2 CIB1 NDUFAB1 ILF2 PSMB3 ICT1 ORMDL2 SDHAF2 EMG1 DCTN3 YIPF3 DKC1 ETHE1 MRPL32 PSMA7 RUVBL1 FGF13 TUBB6 ERH CERS2 GNL2 HSPE1 NDUFA9 PDHB MAD2L2 CDK4 CPN1 HSD17B11 INSIG1 RRAGC PGM1 MSMO1 RNF25 SQLE CEMIP TRIAP1 PPM1K DGAT2 DLST AARS SFXN3 DCPS ABAT MED29 DCTD AMFR STARD4 CKAP4 WSB2 GJB2 LIPH MLF2 PJA1 FAM210B MOB3C CBR3 OPTN EIF4A1 NDUFB4 TAF10 SERP1 CALM2 RASSF4 SLC9C2 LANCL2 SEC14L2 BHLHE22 MLIP LGSN CCDC62 NEU2 SFTA2 PRDX2 PGK1 PSMC4 TERF2IP ALG1 GLRX3 PSMD9 SNRPD3 COQ9 SEC13 EXOSC1 RANGRF NAGK PRMT1 YARS XBP1 IFNGR2 SC5D GRSF1 USP5 FARSB HTATIP2 HMBS TMEM199 IFT20 TOMM22 PSMC3 FUNDC2 TMEM183A TMX2 MCFD2 ALAD CMTM7 ACAT1 CNPY2 LTB4R GGCT PIGH MRPL52 ST3GAL5 NIP7 KCNS3 SMIM13 THOC7 FBXO10 RPS19BP1 FAM174B DDX39A UROD CTPS1 WDR74 ERCC1 ATP6V1G2 ABHD17C FDFT1 MCCC1 GCLC KEAP1 RAB27A MPHOSPH6 TSPAN15 CSMD1 FIS1 PHF23 EVA1A DHPS MRPS7 EMC6 CTBS MTHFD1 PSMG1 TUBB1 ACSM5 HSD17B13 HAX1 IL11RA PDAP1 RRP36 ZC3HC1 LSM4 HNRNPAB STARD5 PRDX6 TUSC2 ECHS1 TIMM17A HIBADH DYNLRB1 RMI2 ANAPC16 ALDH7A1 SDHC ATP5B ZC3H10 SLC25A38 NSDHL PLEKHB1 DNLZ ANAPC15 THAP11 MFSD2A NDUFB8 KLHL4 SSX2IP PBDC1 KIAA1191 ECH1 DCAF11 ATP5G1 PFKP RPF2 ARL4A HIGD1A CENPQ PAIP2B EIF6 GCDH PCCB ECI2 ATP5F1 MPI DUSP14 PITHD1 MFAP3L KCNK1 DNAJC12 PIGM SNRNP35 SMIM19 METTL1 PTPMT1 CD3EAP NSUN2 RHAG MRPS28 ATP5O TIMM22 HEMGN EPB42 CR1L DXO EMC8 PSPH NOB1 TMEM106C FAM47E COQ7 DTD1 GALT SNRPN RNF180 YRDC MRPL49 XRCC6BP1 E2F5 NUGGC SMN2 AKTIP ZFYVE19 RGS9 CUTC QTRTD1 CAPN6 DYNC1I1 SAYSD1 POLR3GL NUDT19 KEL TATDN1 DPYSL4 NPRL2 LOC101683191 LOC101691795 LOC101684595 LOC101675829 LOC101688650 LOC101677848 LOC101680253 LOC101672824 LOC106003381 LOC101691605 LOC101692727 LOC101676649 LOC101692890 LOC101685103 LOC101679966 LOC101678900 LOC101681864 LOC101692996 LOC106004433 LOC101671415 LOC101681454 LOC106005634 LOC106004464 LOC101683501 LOC101676319 LOC106003335 LOC101692051 LOC101676720 LOC106005839 LOC101687847 LOC106006622 LOC101685120 LOC101676849 LOC101682597 LOC101672021 LOC101690488 LOC101684324 LOC101691921 LOC101681532 LOC101693652 LOC101692778 LOC106003364 LOC101680692 LOC101677792 LOC101693300 LOC101672135 LOC101691243 AADACL3 LOC106003500 LOC106003515 LOC101691518 LOC106004276 LOC101670046 LOC106004057 HYKK LOC101671789 LOC101675684 LOC101688994 LOC106006555 LOC106006661 LOC101670834 LOC101672967 LOC101681178 LOC101682402 LOC106003852 LOC106004200 LOC106003700 LOC106006274 LOC101693904 LOC101691097 LOC101688436 LOC101685926 LOC101687332 LOC106005226 DET1 LOC101679407 LOC106005484 LOC101688776 LOC106003404 HARBI1 LOC101691223 LOC106005742 LOC106007008 LOC101675009 LOC101674359 LOC106007378 LOC101671397 LOC101692164 LOC101692773 LOC101689659 LOC101679175 LOC106006132 Top 500 down genes for SARS-CoV-2 infection Day 21 in ferret right cranial lung from GSE160824 Adult female and aged male ferrets were infected with SARS-CoV-2, and 3 tissues were collected on 4 different days post-infection. Uninfected ferret tissues were used as control. Refer to the title & metadata provided for this submission for the timepoint and tissue associated with this data. Data is associated with this publication: Francis ME et al. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets. bioRxiv 2021 Jan 12. PMID: 33469587 CUBN RNF133 CD34 APLNR ASAP2 DAAM1 MAST4 EP300 MYRFL XPNPEP2 ETV1 EPS15 PMEPA1 ENPEP FN1 PLOD2 NR3C2 PDE4D TMEM176A ISYNA1 FBN1 PCSK6 GSK3B UBQLN2 LNPEP GPHN ATXN2 KLF12 CPT1A MED14 RASEF NBEA SH3D19 SRGAP1 POU5F2 COBLL1 FOXP2 NFIB PEAK1 HUNK TET2 SATB1 UTRN SORBS2 NFIA ZBTB20 ARID5B GSN GPD1 EZH2 LAMC1 ADAMTS2 OLFML2A MMP19 SNX8 RAPH1 KCNMA1 GLI1 SGCD PTCH1 TGFBR3 ZFP36L1 KLF11 B4GALT6 TRAK1 MAPT CSNK1G1 BCAS3 MYO19 WIF1 COL1A2 BNC2 LEF1 ABI3BP NAV2 FGF1 TCF7 PNN ZFPM2 TCF7L2 BTRC RERE TAB3 MNT CHL1 XRCC3 COL3A1 ANGPTL4 ANGPTL2 C1QTNF3 PLTP TMCC3 BGN PDGFRA SPECC1L CPNE7 TMEM176B PPP1R14A DDR2 PLXDC2 FSTL1 VWF PCOLCE NRP1 NOVA1 CREB5 TSPAN18 GLI3 ADAMTS17 STARD9 CCND2 EGFLAM HMCN1 ZSCAN9 NATD1 CELF2 MSH4 KANSL1 TIMP2 ITGB3BP VAV3 RXFP1 TNFRSF19 KLF7 MN1 BLID SETD2 MBD5 MAP2 HIVEP2 REL MFAP4 PKD2L1 ITGA11 ZCCHC2 ETV6 ROR2 WISP2 NID1 FNBP4 TEX14 GLG1 NIPBL PAQR8 IGF1R RRH PLSCR4 IRS1 NAV1 CDON BMF ATF7IP BACH2 RNF148 DNM1 ADAM19 MMP2 GPR21 NR1D1 CSMD2 FAM169B RAMP3 C1QTNF1 TSPAN11 PRTG CXCL12 GPR52 CATSPERB MTSS1 SUPT20H ITIH4 UBE2H CSTF3 TNKS BACE1 TIMP3 NEDD4 PRKCA DENND2A GEMIN8 BOC ZC3H11A FAM193B FIP1L1 RIN2 FLT4 HELZ THBS3 REC8 ZNF326 USP3 OBSL1 SCNN1D MEF2D EML5 UNKL ATP6V0A1 MICAL3 PDGFRB FLNC ANKRD17 WASL DGKG ROBO2 SP1 ZBED5 PER2 USP9X SETD7 SEMA6A KDM6A NCOA2 KMT2A ELK1 LPP KMT2C DNAH8 RALGAPA2 NF1 RUNX1T1 SETD5 XKR9 SPRED2 BCL2L11 NOTCH3 EPG5 TEX29 FBXO32 FGD4 TUBGCP5 ZNF800 CAMK2A GIT2 COL5A1 RFX3 SLCO1C1 TNC CBLB GATA6 NTN1 LATS2 ANTXR1 SYNJ1 TIAL1 NEMP1 GPC4 SCAF4 FOXJ2 CNOT4 ARHGAP17 INO80 FGD6 KDM5C LRIG2 PDZD2 HIVEP1 DZIP3 UBN2 TMEM131 KIAA0319 KDM5B JMY MKL2 ZCCHC14 TSHZ1 USP6NL PDE10A EPHA3 ASXL2 BICC1 PDPR TNRC6A GPATCH8 RPRD2 KMT2E BAZ2B PHF21A FAM166A SOS1 PIAS2 CDK14 CPEB3 CPEB4 FBXL20 LRRC37A TTC28 SLIT2 ARHGEF9 HAL AMT ZFC3H1 EPM2AIP1 INO80D HOXA3 ADCY9 SFMBT2 FOXJ3 SVEP1 PPM1E RPS6KA6 LAYN FMOD ACACB SLIT3 MAMSTR HMCN2 COL15A1 ITIH5 ADAMTS7 SFXN4 SESTD1 ERP27 NDNF GAB1 SRRM1 BPTF FAM222B PROSER1 GPR146 HMBOX1 RNF38 HELB SPATA6 TNXB MAU2 GABRA2 MSS51 FITM1 NPAT FAM120C ELMO1 TSHZ3 KAT6B ATXN7 COL6A5 SPTBN4 ICK RIC1 PLEKHM3 KCNAB3 ATXN7L1 ACVR2B RFFL STXBP4 PHEX SCFD2 MAML2 AMHR2 FREM1 SNED1 PHF8 CBFA2T3 C1QTNF7 ZCCHC11 CATSPER2 ANKRD24 RAD51B VGLL4 PRELP ZC2HC1A GRIA3 CCKBR FAM175A C7 RPA4 DUSP22 MUSTN1 FNDC1 ERMARD LOC106005184 LOC106003800 LOC106005762 LOC106004738 LOC106004539 LOC106004036 LOC101684740 LOC106004647 LOC101687369 LOC106006924 LOC101686272 LOC106004710 LOC101687626 LOC101689141 LOC106003433 LOC101678282 LOC106004537 LOC101679208 LOC101683630 LOC101672536 LOC101688539 LOC106007196 LOC106005041 LOC101681919 LOC106003721 LOC101677143 LOC101685008 LOC101691437 LOC101676209 LOC101673601 LOC106006314 LOC106005591 LOC106006942 LOC101677498 LOC101684616 LOC101693847 LOC101686003 LOC101694604 LOC106003323 LOC101682876 LOC106005444 LOC106004536 LOC106006006 LOC101687368 LOC106004099 LOC106007124 LOC101680703 LOC106006213 LOC101674285 ASPA LOC101671185 LOC106003787 LOC101688444 LOC101674836 LOC101677075 LOC101677359 LOC101677006 LOC101676231 LOC106007030 LOC106003903 LOC106003357 LOC106007153 LOC106003975 LOC106007161 LOC101674053 LOC101681950 LOC106007155 LOC101690546 LOC106003710 LOC101675110 LOC106004182 LOC101683901 GRIA4 LOC106006961 LOC101671345 LOC106006514 LOC101670731 LOC101670706 LOC101678687 LOC106006846 LOC106007424 LOC106007110 LOC106004641 LOC101680667 LOC106006359 LOC106003950 LOC101673740 LOC106006598 LOC101693899 LOC101690950 LOC106003649 LOC106006787 LOC106003755 LOC101683481 LOC101681091 LOC106004625 LOC106005938 LOC106004545 LOC101693456 LOC101693458 RNASE13 LOC101678268 LOC101676673 ASB11 LOC101684869 LOC106006441 LOC106003655 LOC106005464 LOC101688340 LOC101686564 LOC101679006 LOC101683078 LOC101680314 LOC101670362 LOC106005431 LOC101685231 LOC101675172 LOC106004840 LOC101679902 LOC101691924 LOC106004355 LOC106006490 LOC101685723 LOC106004223 LOC101684326 LOC106004973 LOC106004317 LOC101678916 LOC106006494 LOC106005948 LOC106005925 Up-regulated in COVID-19 patients We found this list of genes by using DESeq2 to analyze the metadata from GSE171110. MYH9 MAOA SLC36A1 TRIM55 UHRF1 UTS2R GDF15 ANPEP GMIP TAAR1 CHPF STX3 PTCRA TBC1D3P5 SLC26A6 DPEP1 MYO1D RNF24 SIRPD ACE2 IFITM3 TLR4 SLC16A8 EP300 ANXA3 IFITM1 SLC22A18 PKM SCN2B MIPOL1 FABP2 ST14 FURIN ADAM9 ZBTB7B CENPF JAK2 GOLGA2 SIRPA CIT ERG F5 PSG6 UBTD1 MAPK14 TMEM54 SERPINE1 FLT1 CRISP3 TCN2 HEPH OAS1 SULT1B1 AOC1 PTX3 GRIPAP1 CTSD FN1 PLOD2 ADAM17 PRSS50 TRIM25 WASF1 BRCA1 MTARC1 ARHGEF11 POR PCSK6 MGAM OASL CCL25 AGTRAP STOM SIL1 TBKBP1 YWHAH FERMT3 IL17RA VSIG4 FRMD3 GUCY2C RPH3A FAM72B UAP1 SPI1 GGH PLEC IL10 MX1 MYD88 NEU1 HPN TLN1 CABLES1 FGFR4 ARHGAP18 WDR34 FZD5 EXOSC4 STXBP2 PSMC3IP BCL2A1 CAV1 DDAH2 SERPING1 MYO10 CEACAM6 PCP4L1 TFF3 MUC21 SDC1 ARFGEF3 AK4 NT5DC2 LMNTD1 SRGAP1 FBXL13 ASS1 BEND7 TENT5C CEBPD KLF5 IFI27 EXT1 MCTP2 OMG S100P RTEL1P1 METTL7B PPL SHOC1 APOBEC3A PTGFR CEP295NL EPCAM GADD45A ANKRD33B SLPI MTND5P32 TRIM7 TACSTD2 LCN2 ABCA1 TMIGD3 TPST1 IGLC2 DDX10P1 DHRS9 SLCO2B1 NACC1 C1QC IL4R TOR1B PGD GRINA ALOX5 EMILIN2 LRP10 QSOX1 SHKBP1 ITGB5 PRAM1 PLOD1 SLC16A3 EHBP1L1 NDST1 MARCO ITGAM PDIA4 GRN HK3 SLC6A6 FBXO6 ABHD2 SLC38A10 GALNS ZYX SLC11A1 IGKV1-9 PLK1 CLTCL1 IGHV3-21 IGKV1D-8 TIMP1 FLVCR2 EXO1 PYCR1 DHCR24 IGKV2-24 MYBL2 TOP2A IGHA2 TICRR IGLV2-8 KIAA1958 IGKC IGHV3-33 ZWINT CDCA8 IGHV4-61 VSIG10L CCNA2 IGHA1 CLSPN TK1 TROAP IGKV6-21 IGHV4-55 ALDH1L2 EZH2 C3AR1 SAP30 IGLV9-49 IGHV4-34 NAIP IGHV3-22 LMNB1 CCNB2 MACC1 TUBG1 SMARCD3 PLBD1 SQOR IGHV3-15 IGKV2D-28 CEBPA IGHV3-66 FKBP9 IGHV2-5 IGLV2-5 IGHV4-39 GTSE1 CDKN3 UBE2C IGHV3-73 IGKV2-40 KNL1 IGHG4 AURKB IGHG2 KCNE1 E2F2 IGHV3-13 IGKV1D-37 IGHV1-2 NEK2 SHCBP1 IGHG1 IGKV3-20 MGST1 LDLR NOL3 KIF18B IGKV1-6 NUF2 IFI44 RNASE2 FLT3 DEPDC1B IGKV2D-29 EAF2 CDCA5 HMMR IGHV3-30 MCEMP1 IGKV4-1 IGFBP2 IGLV2-18 RBBP8 IGHV3-7 SPAG5 TMEM38A FAM72D ELL2 FAM72A IGHV6-1 ARHGAP29 LHFPL2 IGHJ2 GALNT2 IGKV1-17 ITGA7 ERLIN1 RAB13 ACVRL1 FKBP5 LILRB5 BUB1B TNFRSF17 OTOF MCM2 IGHV3-43 WFDC1 IGHJ5 KIF2C CDC25A KIF14 IGLV3-10 MZB1 IGKV2D-30 IGKV2D-40 NUDT16 OLAH ASPM IGKV1D-16 RNASE1 SERPINB10 TDRD9 MS4A4A AURKA TIMP4 DLGAP5 ESPL1 IGKV3D-20 IGLV1-40 BUB1 IGHJ4 IGKV1-12 ZBTB32 IGLV2-11 IGLV1-44 MAFG KIAA0895L RRM2 IGHV1-24 SLC1A3 CDK1 SIGLEC11 SMAD1 FABP5P7 CLEC1B PAQR4 CDC6 E2F1 BIRC5 IGHV4-28 ORC1 C1QB POLQ CES1 KIFC1 IGLV4-60 IGKV1-39 IGLV7-46 KIF4A NIBAN2 IGHJ6 CD163 IGHV4-59 DHFRP1 IGHV3-49 EPSTI1 IGKV1-27 IGHV3-64 SAPCD2 SH2D4A ITGA1 IGHV3-69-1 FCRL5 SIGLEC16 HGF IGKV3-15 CARD6 IGLV4-69 LAMC1 TP53I3 MCM10 IGLV7-43 DOCK1 RGS16 IGLC3 KIF15 TRPM2 SMTN IGKV5-2 IGHV5-51 PPARG FAM72C ASGR2 IGHV3-72 SLCO4A1 MYDGF GAPDH ADAMTS2 PRR11 IGHV3-48 CDCA2 IGKV1-33 C2 IGHV4-4 EPHB2 GRB10 PDIA5 GLDC IGLV1-47 IGHV3-74 PRRT4 IGLV1-36 IGLV2-28 KIF11 IGLJ3 IGHV3-20 IGHV2-70D IGHV2-26 ACVR1B HDLBP IGHV2-70 IGLV3-25 ECHDC3 IGKV3-7 IGKV3-11 NME1 BRCA2 IGKV2D-24 IGKV2-28 IGHV1-69 TPX2 ALOX15B STIL CCNB1 IGLL5 IGKV2-30 PADI2 MERTK ANLN IGHV1-46 NCAPH FER1L4 OLFML2A FAM20C OPLAH DEPP1 IGHGP GLDN IGHV3-23 CEP55 MMP19 IGLV2-23 IGKV1D-39 IGKV2-29 CDCA3 TEX2 BATF2 IGLV3-16 CDC20 KIF23 IGLV3-19 IGLV10-54 PKMYT1 SKA1 IGHG3 IGHV1-18 AMPH UNC13B HJURP TRIP13 CENPU CENPW IGLV3-1 TTK IGHJ3 IGKV1-5 IGLV2-14 IGHV1-69D GPER1 SYN2 IGLV1-51 HP IGKV3D-15 JCHAIN CDC42BPA SPATS2L ARHGAP23 MKI67 SH3PXD2B LDHA NTSR1 IGKV1D-33 IGHV3-11 SORT1 CDC45 IGLV6-57 ALDH4A1 TRIM71 KIF20A IGKV3D-11 DTL KCNMA1 ARNTL2 TBC1D2 IGLV3-21 IGHV3-53 SPTLC2 ICAM5 SCD CD163L1 IGKV1-16 RNASE3 MAP3K6 NCAPG AC006946.1 TYMS GLI1 G0S2 CST7 TCN1 CAMP B4GALT2 B4GALT5 CDKN1A TUFT1 NOTCH1 GADD45G APLP1 IL18RAP SLC2A3 CILP2 MMP1 MANF VPS9D1 SLC2A5 TRAM2 DSCC1 GADD45B BATF AQP10 RPL11P3 ELANE B3GNT9 CTSG FAM20A CCNE1 OSM FOXM1 LTF ITGA2B RHOV CGN ITGB4 USP32 COL17A1 PLEKHH3 TONSL LAMB3 CNKSR1 MROH6 CARD14 SERINC2 KRT80 SLC7A5 WLS SPARCL1 WNT11 SORCS2 CLU PAX3 FRAT1 ALPL MMP8 WNT5B JAG1 CNGB1 IRF4 CD63 TBC1D8 UPP1 INSL3 PRC1 MAP2K6 TMEM88 TRIOBP SLC24A3 TFE3 BCL3 DHX34 TECPR2 GLT1D1 FAM157A PCNX1 NBEAL2 CEBPB AP5B1 TNK2 CREBBP HELZ2 C10ORF105 GLIS2 PHC2 CUX1 RBM47 OGFR SBNO2 RAB43 TNRC18 CENPN ARHGAP11A CDC25C E2F8 CENPA CCNA1 IRF7 MXD3 MTFR2 RAD54L ESCO2 EME1 FANCI ZBP1 TCF19 DUSP13 CHEK1 RAD51 GINS2 CKAP2L TNFSF14 CHAF1B IQGAP3 PARPBP FAM83D LILRB4 SKA3 SPC24 GPR84 CLEC5A OIP5 CHIT1 LANCL3 ERCC6L NUSAP1 FCGR1A PBK CENPI CCDC88B AUNIP SPC25 MELK CENPM DEPDC1 CCNF HMGB2 NDC80 INCENP IGF2BP3 CENPE NEIL3 RAD51AP1 FCER1G BVES RETN XIRP2 CYP1A1 BEX1 S100A9 MYBPC3 PLIN4 DOC2B PSAT1 CDT1 POLE2 SIGLEC1 CXCL3 CD274 GINS1 COL24A1 FBXO39 IL1R2 GPR141 IL1RN CHAF1A USP18 CMPK2 KIF18A CCNE2 FSTL4 SPACA7 OSCAR CLEC4E DHFR MAB21L3 SUCNR1 NAV3 TMEM52B TIMELESS CD177 CLEC4D TNFAIP6 ACOXL NRN1 CPNE5 KL SOCS3 ADAR PARP9 SAMD9L ADM NFIL3 LRRC4 SLC7A11 SELP TARM1 FAP INHBA BASP1 FOSL1 TRIM6 ARG1 C5AR1 PLAU GCKR PDE2A ITGA8 CHST8 PCOLCE2 SPAG4 GSG1L CD59 CAV2 CLIC4 LY6E EPAS1 TXN SPARC EGFL7 JUNB JUN SLC34A2 FABP5 DRAM1 FBXO16 ITM2C MYH10 DDR2 PLXDC2 PTGR1 CHST1 ESAM CA4 PIM3 JDP2 PDPN ALOX5AP MYLK FNDC3B FSTL1 VWF GYG1 LRG1 GNS VCL OIT3 SLC8A2 KDM6B CREB5 KIFC3 SAMSN1 ZC3H12A RGMA TGFB1I1 MPZ FAM209B IL27 SLC22A14 HSPA6 CCM2L BPI TRIML2 LY6G6E SAMD14 PADI4 OLFM4 GP6 CR1 SIGLEC9 S100A12 PRR16 OR2B6 PGLYRP1 LONRF3 ADAMTS3 NATD1 LOXHD1 TLR9 NTNG2 DCC SAMD15 GJA4 TG HMGN5 TP53I11 MUC1 CITED4 TOR4A IRF2BPL CSRNP1 BAMBI CHAC1 CDC42EP3 PFKFB3 LHX1 UBE2S ALAS1 HMGB3 MND1 MSRB2 HSP90B1 EPDR1 PRDX4 PTTG1 FLOT2 PHLDA3 TIMP2 MGLL FGF13 GMNN LAMB1 SEC11C SSC4D SDF2L1 MXD1 TTC7B E2F7 CADPS2 GP1BB DQX1 C1ORF226 KCND1 COL7A1 XKR4 HYAL1 PRR15 GAS2L1 PIR ITPKC MAP2 MMP9 DIAPH3 GALNT18 VEGFC DHRS13 IL1R1 B3GNT8 ITPRIP SHROOM4 ANKRD9 TNNT1 RBP5 SLC6A9 NNMT BEAN1 FEN1 JSRP1 S100A8 TNNT3 TLR2 GJD3 ZCCHC2 SMOX SELL POU2AF1 TREML1 LY6G6D SLC22A1 FAM92B DERL3 NALCN OLR1 CRACR2B GP9 TMEM40 SLC1A4 CD38 NFE2 HSPB9 CYP1B1 COL9A3 CDKN2C ST8SIA5 PCSK9 CEACAM8 VNN1 IFI6 DPY19L2P3 SLC51A TMEM132D PAQR6 CRISPLD2 NOXRED1 ORM1 MCM4 FAM111B TRHDE LMNB2 APOBEC3B CHAC2 SP100 DDX60L PPP1R3D CKAP4 PSTPIP2 SMIM10 UBN1 LIPH MEIS2 CORO2A SLC22A4 CETP EMP1 P2RY1 PKHD1L1 ORC6 CEACAM1 ETV7 GPT2 CHST15 BAZ1A CTNNAL1 RRAGD MDK RHBDF2 PLSCR4 VNN2 PXK IL18R1 PIK3AP1 CFLAR GTPBP2 SERPINA1 PYGL LILRA3 CTSA MSRB1 DYSF DEFA4 RAB31 MTX1 AZU1 MYL9 PRTN3 SERPINB1 MPO CALB1 HPDL DENND3 TRIB1 NEK6 AIM2 UPB1 AANAT GPR17 FCGR1B PLA2G4F DNM1 ZBTB47 LSMEM2 ITGB3 CD70 SHOX IGHM ADAM19 TUBB3 MMP2 SPOCD1 CALD1 PLSCR1 CHRNA2 ADAMTS9 NR2E1 KIAA1614 GPRC5D AMPD1 LMAN1L HBE1 PLXNB3 SCN5A UGT3A2 ITGA9 FANCA STAB1 TP73 LRFN1 PYGM SH3TC2 SEMA3B ALPK3 ZDHHC19 RASGRP4 HLA-H HPD STAB2 CCSER1 DDN KLHL14 CACNA1E PRUNE2 CSNK1A1L FCAR LPO HOXB13 PRKCD USB1 UBE2J1 FUT7 APOBR SIGLEC5 LILRA6 LILRA5 FGR SCO2 AQP9 DOK3 HLX IGF1 PRL UCHL1 CASP5 DOT1L ASIC4 MAP4K4 TERT XBP1 TIMP3 CA12 IFNGR2 EGF TXNDC5 GBA TOM1 SH3GLB1 APMAP FKBP11 CD82 PHGDH WIPI1 ESYT3 IRAK3 LRRK1 COX6B2 DMC1 KCNJ15 BST1 LTB4R MANSC1 SLC25A10 GAB2 STBD1 ASAP1 XRCC2 NOS1AP FFAR2 ZFHX2 SLC12A8 KCNJ2 RBP4 DNAJB11 SPATS2 DLL4 RAP1GAP TRIP6 CCDC17 PPP1R3B STOX2 ABCB6 NLGN3 LRP3 FA2H ATP9A FDXR CYP19A1 ACSL1 RGL4 BCL6 CARD17 NEXN PROK2 ALPK1 ANKRD22 CACNA1A ATP7B CYSTM1 KCNH7 JAK3 CCDC71L HSPB6 SLC26A8 FLOT1 RRP12 SSH1 ADCY4 MFN2 SLC9A1 ABLIM3 GAS6 NES TXNDC11 SPHK1 AGFG1 PLIN3 TRIM9 NLRC4 GP1BA LRPAP1 BFSP2 TRPV5 HDAC4 BMX GAS7 ECE1 TGFA SCNN1B LRRN1 CEL DGKI CDKN2A PARD3 OR52W1 ATP2C2 RALGAPA2 PTPRF EPB41L4B CAMKK2 INHBB SRPK1 GCNT1 SLC16A14 BHLHA15 GABRR2 SERPINE3 SATB2 MSRB3 GTF2IP13 ARHGAP6 TMEM119 ARSB COL10A1 LRWD1 NQO2 CIP2A PCLAF BIK AP3B2 WDFY3 TLR5 LRRC59 PEAK3 SPATC1 ADAMTSL4 MAP1A ADGRE2 MKNK1 TFPI HK2 SCN9A ABCB9 FGD4 RSC1A1 FFAR1 SEMA4A TNFRSF13B FCGR1CP HRH2 LTBP1 LEP PCYT1B GTPBP1 FFAR3 ABCA13 PEAR1 SLCO4C1 ABCC6P2 F12 ALOX12 AKR1C1 SLC2A14 RRBP1 SGO1 UGCG CREB3L1 DNMT3B ALDH1A2 HCAR1 GALNT14 TWIST2 MET MTF1 RECQL4 POC1A HSD3B7 MT1G SPSB1 CSGALNACT2 LHFPL6 TEAD3 ASPH EHD2 GINS4 BMP8B MTMR3 RHOBTB1 ZNF319 DLC1 FSTL3 ADM2 AIF1L MAOB GMPPB MYL6B PIF1 NBPF14 LGALSL PFKFB2 FAT2 CPE ZNF608 PINLYP CMYA5 SBF2 QPCT ANKRD28 DNAH17 FBXL19 PDE3A KCNK5 EFCAB12 ZNF787 WDR62 DDIAS SVIL LIMK2 GRAMD1A UNC5A KREMEN1 PPP4R1L PHF21A PLPP3 CLPB NOCT AL353625.1 TTLL7 PRRG4 CDK14 H2AC11 H4C9 H2AC6 H2BC13 H2BC11 H1-2 H2AC7 H3C8 H4C11 H2BC4 H2AC8 H3C4 H2BC6 H2BC8 H4C4 H2BC18 H2AC17 RIPOR3 H3C12 H2BC7 H1-4 MED12L AL136295.5 AL669918.1 CPEB4 SIPA1L2 AC068580.4 AC009779.4 MGAM2 SGO2 AL162615.1 KMT2D AC080023.2 PHKA1 ATP11A EIF4G3 MFSD14C LRRFIP1P1 H2BC5 H2BC12 H2AC15 H1-0 ST3GAL2 AL109918.1 PIMREG EMILIN1 ACOX2 C1RL PRKCB STRIP2 ANO10 PDLIM7 SLC9A8 REXO5 KCNK7 DOCK4 KLHL2 SCN1B CCDC162P MAN1A1 PLK4 KIF1B SH2B2 COL23A1 TSPAN9 PRDM6 SCUBE1 ZC3H3 TMEM92 ARHGAP42 ENTPD7 PRR26 KIF24 AATK ZNF215 P2RX1 ANKRD2 IGLC1 CHD7 CADM1 PGS1 ARID3A WNK4 BNIP5 TNFAIP8L3 SPSB4 GPR27 VSTM2L C4ORF48 MEIS3 SLC44A1 GPRIN1 IFI27L1 SYNC DZIP1L EFCAB2 FIGN PHTF1 BTBD19 SIX5 KCNT2 RAB42 CCR10 MMRN1 RAPGEF5 KCNN3 PLXNC1 TMED8 C11ORF87 ZNF438 RNF208 DENND1A CHRNB2 JCAD HTRA3 KLF14 ACSS3 TCTEX1D1 SHROOM2 H3C15 CMTM1 ST20-MTHFS SLX4 XKR3 PROB1 MAP1LC3B2 CHKB-CPT1B CCDC150 PLEKHM3 PRICKLE4 HOMER3 DENND2C CDH7 NUGGC ARHGAP28 HNRNPUL2-BSCL2 MEF2B CKLF-CMTM1 TMEM240 RNF103-CHMP3 XK RSPH9 NSUN7 TCEAL9 CKMT1B NMNAT2 LY75-CD302 KCTD14 CLEC18A FAM151B NECAB1 FAM47E-STBD1 HIP1 ELOVL3 SMTNL1 RAB19 CLDN9 PLPPR3 DACH1 TCTEX1D4 DNAH10 KLHL30 LINGO3 KBTBD12 KCNG2 INSC ST6GALNAC3 INSC ST6GALNAC3 EFR3B ATP2A1 IGKJ5 SYTL4 SLIT1 MAN2A2 NSG2 SYT5 ADGRG3 TEDC2 HASPIN KCNE1B C4ORF17 CYREN FKBP9P1 NMRAL2P OPRL1 INAVA DAAM2 H2AX CEBPE ROPN1L RNF175 CMTM5 LY6G6F CCDC36 DEFA1 CEND1 ANO2 B9D1 TAS1R3 ZNF429 DYRK3 SLC37A3 NLRP12 CNIH2 CEACAM4 CNGA4 CAPN13 REM2 PLIN5 LHX4 FAM3C2 IGLVI-70 AC141272.1 IGHV1-3 MTX1P1 IGLJ2 NSFP1 NHLH1 GPR42 OR2B2 LLCFC1 H3C3 ANKRD34B LY6G6C TPTEP2-CSNK1E FAM124A VWA7 H2AJ PNPLA1 SEPTIN5 MPIG6B H2BC9 MINDY1 H2BC21 H4C5 DRC7 TSHR MLNR ARMC12 AC007207.1 IGHV1-67 AC114744.1 CTBP2P8 IGHV3-41 IGLV1-50 AC135068.2 NRADDP AC091959.3 OLFM5P AL671986.1 IGLC7 AC018755.3 AC116353.5 IGHV3-71 IGHV1-58 ZNF969P CCDC140 FAM27B Z95152.1 AL121758.1 SDR42E1P5 IGLV5-48 AL031432.2 IGLC6 CCNG1P1 IGHJ1 IGLV8-61 CRACD H4C8 MTCO2P33 IGLV3-22 IGKV1OR2-108 AC005255.1 IGHV5-10-1 IGHV3OR15-7 C5ORF67 IGKV3OR2-268 RLN3 AC104837.2 CA15P1 CC2D2B AC068631.3 IGHV3OR16-12 AC108463.1 KRT8P43 AC233755.1 IGHV3OR16-8 AC239798.1 ODCP IGHJ3P CHORDC1P4 ASS1P1 AC090114.3 AC116353.6 AC009286.3 HSPE1P18 CFAP77 IGHV1OR15-9 AC135068.9 AC136616.2 AL109809.1 IGHV1OR15-4 RPL9P33 IGHV3-38 AC247036.3 LIPM AC010886.1 PLAAT2 AGGF1P8 PPP1R2P1 CLRN1 AC009570.2 IGHV3OR16-13 IGHV1OR16-1 IGLJ1 PDLIM1P4 AC018755.2 SMIM34A HK2P1 AC104451.1 IGHV3-42 AC099489.2 ZDHHC4P1 EIF1AXP1 MFSD13A AC100756.2 AC000041.1 OR2W6P IGLV4-3 RPS29P14 AC103810.9 AC217785.1 IGLV3-9 AC084871.1 AC134981.1 ATP5PDP4 AC026877.1 ARID3BP1 AC008763.3 ERFE AC018638.8 AC139494.1 AC006059.2 AC009927.1 AL163636.2 PPP1R2P6 AC068946.2 CNBD1 H3P13 AC114878.2 CU151838.2 IGHV1-14 IGHEP2 OXCT2 KRT8P26 AC247036.4 H2AC19 AL022722.1 HNRNPA3P6 LARP1P1 LINC01347 AL133517.1 AC104561.2 AC093512.2 IGHV3OR16-9 AC103563.5 AC007325.1 IGHV1OR16-4 FO082796.1 NAP1L4P1 AC138811.2 AC011498.4 C5ORF47 IGHV1OR15-2 LILRP1 IGHV1-12 AC131392.2 BNIP3P26 AC245884.2 IGHV7-4-1 HROB MIXL1 AC073135.6 AC010627.1 CDK2AP2P2 AC022384.1 HAUS1P1 H2BC17 KIAA0319L AC099489.1 SPATA20P1 ATP8A2P2 IGHV3-63 AL662899.3 CT75 DUXAP7 IGHV3-64D IGHV3-47 CICP19 CDC20P1 AL031777.1 AC112777.1 AL353803.3 AC139495.1 IGHV3-76 DNM1P34 RBMS1P1 AC006042.2 AC134879.2 IGHV1-45 NAIPP1 IGLV5-45 IGHV3-36 NLRP9P1 AC114781.1 RAC1P2 AC244226.1 AD000671.2 MACIR AC000095.1 RAB43P1 H2BS1 IGHV3-52 IGHV7-81 IGLV5-37 AC020636.2 H3C14 RPL22P24 USP41 DOCK8-AS1 RPL17P10 AL157938.1 AL365273.2 AL683842.1 AC098934.1 KRT18P34 SEPTIN4 AL354877.1 PPIAP29 H2AC13 AL035456.1 AC138827.1 ADGRF5P1 AL049634.1 MMP27 IGHV3-60 REXO1L1P NAIPP3 AL645568.2 AC012569.1 XIAPP3 IGKV6D-21 AC139495.2 YBX2P1 IGHV3-35 H2AC18 CALHM5 AC097065.1 HMGB1P9 RPL30P7 CPNE6 IGHV3-19 AC244260.1 NOS2P3 MTCO1P11 IGLV3-27 GLULP5 DUX4L50 AC233755.2 IGHV1-68 H2AC20 AC010878.1 RPL7P51 AC069431.2 ZNF887P AC243913.10 AC234301.3 DPRXP2 H2BC20P NOTCH2NLA IGHV1-17 H2BC15 AC091304.3 H1-12P LIN7A AC008984.5 SUMO2P19 RPL7P18 IGHV1OR21-1 IQCF3 TPI1P2