Small molecules which mimic amyotrophic lateral sclerosis
Canned Analysis
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General Information
AccessionDCA00009322
TitleSmall molecules which mimic amyotrophic lateral sclerosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the amyotrophic lateral sclerosis gene expression signature in the Spinal cord grey matter - sporadic ALS cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c03fe467bea600fb84ee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:1006
Cell TypeSpinal cord grey matter - sporadic ALS
DO IDDOID:332
Disease Nameamyotrophic lateral sclerosis
Organismhuman
UMLS CUIC0002736
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM6826, GSM6829, GSM6830, GSM6831
Perturbed SamplesGSM6827, GSM6828, GSM6834, GSM6835, GSM6836
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE833
Gene Expression Omnibus
Amyotrophic lateral sclerosis (Lou Gehrig's Disease)
14
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