Small molecules which reverse abdominal aortic aneurysm
Canned Analysis
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General Information
AccessionDCA00009329
TitleSmall molecules which reverse abdominal aortic aneurysm
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the abdominal aortic aneurysm gene expression signature in the Aorta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1be17e467bea600fb83dc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:1011
Cell TypeAorta
DO IDDOID:7693
Disease Nameabdominal aortic aneurysm
Organismhuman
UMLS CUIC0162871
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1150703, GSM1150704, GSM1150705, GSM1150706, GSM1150707, GSM1150708, GSM1150709, GSM1150710
Perturbed SamplesGSM1150689, GSM1150690, GSM1150691, GSM1150692, GSM1150693, GSM1150694, GSM1150695, GSM1150696, GSM1150697, GSM1150698, GSM1150699, GSM1150700, GSM1150701, GSM1150702
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47472
Gene Expression Omnibus
Differential gene expression in the proximal neck of human abdominal aortic aneurysm
7
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