Small molecules which mimic liver cirrhosis
Canned Analysis
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General Information
AccessionDCA00009330
TitleSmall molecules which mimic liver cirrhosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the liver cirrhosis gene expression signature in the Cirrhotic Livers and Normal Kidneys from the same patients cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1be0ce467bea600fb83d6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:1012
Cell TypeCirrhotic Livers and Normal Kidneys from the same patients
DO IDDOID:5082
Disease Nameliver cirrhosis
Organismhuman
UMLS CUIC0023890
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1232077, GSM1232078, GSM1232079, GSM1232080, GSM1232081, GSM1232082, GSM1232083, GSM1232084, GSM1232085
Perturbed SamplesGSM1232086, GSM1232087, GSM1232088, GSM1232089, GSM1232090, GSM1232091, GSM1232092, GSM1232093
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50892
Gene Expression Omnibus
Expression data from kidney biopsies of liver disease patients
7
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