Small molecules which reverse MELAS syndrome
Canned Analysis
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General Information
AccessionDCA00009333
TitleSmall molecules which reverse MELAS syndrome
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the MELAS syndrome gene expression signature in the Muscle - Striated (Skeletal) (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bc89e467bea600fb8314
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:102
Cell TypeMuscle - Striated (Skeletal) (MMHCC)
DO IDDOID:3687
Disease NameMELAS syndrome
Organismhuman
UMLS CUIC0162671
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM24652, GSM24653, GSM24654
Perturbed SamplesGSM24655, GSM24656, GSM24657, GSM24658
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1462
Gene Expression Omnibus
Mitochondrial encephalomyopathies associated with mitochondrial DNA mutations
7
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