Small molecules which mimic autism spectrum disorder
Canned Analysis
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General Information
AccessionDCA00009366
TitleSmall molecules which mimic autism spectrum disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the autism spectrum disorder gene expression signature in the nasal olfactory stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c236e467bea600fb85da
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1035
Cell Typenasal olfactory stem cells
DO IDDOID:0060041
Disease Nameautism spectrum disorder
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1551540, GSM1551542, GSM1551544, GSM1551546, GSM1551548
Perturbed SamplesGSM1551539, GSM1551541, GSM1551543, GSM1551545, GSM1551547, GSM1551549
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63524
Gene Expression Omnibus
Identification of transcript dysregulation in patients with Autism Spectrum Disorders
7
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