Small molecules which reverse autism spectrum disorder
Canned Analysis
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General Information
AccessionDCA00009369
TitleSmall molecules which reverse autism spectrum disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the autism spectrum disorder gene expression signature in the dental pulp cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cbf1e467bea600fb8aaa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1036
Cell Typedental pulp cells
DO IDDOID:0060041
Disease Nameautism spectrum disorder
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1530118, GSM1530119, GSM1530120, GSM1530121, GSM1530122, GSM1530123, GSM1530162, GSM1530163, GSM1530164
Perturbed SamplesGSM1530165, GSM1530166, GSM1530167
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE62632
Gene Expression Omnibus
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
14
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