Small molecules which mimic autism spectrum disorder
Canned Analysis
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General Information
AccessionDCA00009372
TitleSmall molecules which mimic autism spectrum disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the autism spectrum disorder gene expression signature in the lymphoblastoid cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c25ce467bea600fb85ea
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1038
Cell Typelymphoblastoid cells
DO IDDOID:0060041
Disease Nameautism spectrum disorder
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM736476, GSM736477, GSM736478, GSM736479, GSM736480, GSM736481, GSM736482, GSM736483, GSM736484, GSM736485, GSM736486, GSM736487, GSM736488
Perturbed SamplesGSM736489, GSM736490
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29691
Gene Expression Omnibus
Expression data from patients with global developmental delay and autistic features and normal controls
7
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