Small molecules which reverse autism spectrum disorder
Canned Analysis
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General Information
AccessionDCA00009377
TitleSmall molecules which reverse autism spectrum disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the autism spectrum disorder gene expression signature in the frontal cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c771e467bea600fb886c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1040
Cell Typefrontal cortex
DO IDDOID:0060041
Disease Nameautism spectrum disorder
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM706428, GSM706429, GSM706430, GSM706431, GSM706432, GSM706433, GSM706434, GSM706435, GSM706436, GSM706437, GSM706438, GSM706439, GSM706440, GSM706441, GSM706442, GSM706443
Perturbed SamplesGSM706412, GSM706413, GSM706414, GSM706415, GSM706416, GSM706417, GSM706418, GSM706419, GSM706420, GSM706421, GSM706422, GSM706423, GSM706424, GSM706425, GSM706426, GSM706427
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE28521
Gene Expression Omnibus
Transcriptomic Analysis of Autism Brain Reveals Convergent Molecular Pathology [array data]
21
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