Small molecules which reverse cystic fibrosis
Canned Analysis
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General Information
AccessionDCA00009393
TitleSmall molecules which reverse cystic fibrosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the cystic fibrosis gene expression signature in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c759e467bea600fb8860
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1048
Cell Typeliver
DO IDDOID:1485
Disease Namecystic fibrosis
Organismmouse
UMLS CUIC0010674
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM823870, GSM823871, GSM823872, GSM823873
Perturbed SamplesGSM823874, GSM823875, GSM823876, GSM823877
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE33319
Gene Expression Omnibus
Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice.
7
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