Small molecules which mimic myotonic dystrophy type 1
Canned Analysis
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General Information
AccessionDCA00009394
TitleSmall molecules which mimic myotonic dystrophy type 1
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the myotonic dystrophy type 1 gene expression signature in the embryonic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c75ee467bea600fb8862
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1049
Cell Typeembryonic stem cells
DO IDDOID:11722
Disease Namemyotonic dystrophy type 1
Organismhuman
UMLS CUIC0027126
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM172874, GSM172875, GSM172876
Perturbed SamplesGSM172880, GSM172881, GSM172882
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7179
Gene Expression Omnibus
Comparison of gene expression data between wild-type and DM1-affected undifferentiated hES cells.
14
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