Small molecules which reverse myotonic dystrophy type 1
Canned Analysis
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General Information
AccessionDCA00009405
TitleSmall molecules which reverse myotonic dystrophy type 1
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the myotonic dystrophy type 1 gene expression signature in the mesodermal precursor cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c5a2e467bea600fb8784
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1053
Cell Typemesodermal precursor cells
DO IDDOID:11722
Disease Namemyotonic dystrophy type 1
Organismhuman
UMLS CUIC0027126
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM172856, GSM172857, GSM172858
Perturbed SamplesGSM172859, GSM172860, GSM172861
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7177
Gene Expression Omnibus
Comparison of gene expression data between wild-type and DM1-affected Mesodermal Precursors Cells (MPC)
14
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