Small molecules which reverse bipolar disorder
Canned Analysis
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General Information
AccessionDCA00009433
TitleSmall molecules which reverse bipolar disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the bipolar disorder gene expression signature in the frontal cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bc79e467bea600fb830c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:107
Cell Typefrontal cortex
DO IDDOID:3312
Disease Namebipolar disorder
Organismhuman
UMLS CUIC0005586
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM123212, GSM123213, GSM123214, GSM123215, GSM123216, GSM123217, GSM123218, GSM123219, GSM123220, GSM123221, GSM123222, GSM123223, GSM123224, GSM123225, GSM123226, GSM123227, GSM123228, GSM123229, GSM123230, GSM123231, GSM123232, GSM123233, GSM123234, GS
Perturbed SamplesGSM123182, GSM123183, GSM123184, GSM123185, GSM123186, GSM123187, GSM123188, GSM123189, GSM123190, GSM123191, GSM123192, GSM123193, GSM123194, GSM123195, GSM123196, GSM123197, GSM123198, GSM123199, GSM123200, GSM123201, GSM123202, GSM123203, GSM123204, GS
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5388
Gene Expression Omnibus
Bipolar disorder: dorsolateral prefrontal cortex
7
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