Small molecules which mimic Parkinson's disease
Canned Analysis
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General Information
AccessionDCA00009446
TitleSmall molecules which mimic Parkinson's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Parkinson's disease gene expression signature in the Dorsal motor nucleus of Vagus nerve cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cf3ce467bea600fb8c40
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorbenreadhead
CREEDS IDdz:1080
Cell TypeDorsal motor nucleus of Vagus nerve
DO IDDOID:14330
Disease NameParkinson's disease
Organismhuman
UMLS CUIC0030567
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM488111, GSM488113, GSM488115, GSM488117
Perturbed SamplesGSM488119, GSM488121, GSM488123, GSM488125, GSM488127, GSM488129, GSM488131
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE19587
Gene Expression Omnibus
Parkinson's disease: post-mortem medullary regions
21
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