Small molecules which reverse Parkinson's disease
Canned Analysis
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General Information
AccessionDCA00009449
TitleSmall molecules which reverse Parkinson's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Parkinson's disease gene expression signature in the PD medullas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bcade467bea600fb8328
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatoralanstern
CREEDS IDdz:496
Cell TypePD medullas
DO IDDOID:14330
Disease NameParkinson's disease
Organismhuman
UMLS CUIC0030567
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM488111, GSM488112, GSM488113, GSM488114, GSM488115, GSM488116, GSM488117, GSM488118, GSM488131, GSM488132
Perturbed SamplesGSM488119, GSM488120, GSM488121, GSM488122, GSM488123, GSM488124, GSM488125, GSM488126, GSM488127, GSM488128, GSM488129, GSM488130
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19587
Gene Expression Omnibus
Parkinson's disease: post-mortem medullary regions
21
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