Small molecules which mimic dilated cardiomyopathy
Canned Analysis
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General Information
AccessionDCA00009464
TitleSmall molecules which mimic dilated cardiomyopathy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the dilated cardiomyopathy gene expression signature in the Myocardial tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bb9ce467bea600fb829e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:115
Cell TypeMyocardial tissue
DO IDDOID:12930
Disease Namedilated cardiomyopathy
Organismhuman
UMLS CUIC0007193
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM244338, GSM245340, GSM245343, GSM245878, GSM245879, GSM245890, GSM245891, GSM245892, GSM246118
Perturbed SamplesGSM245880, GSM245881, GSM245886, GSM245888, GSM245889, GSM245965, GSM245966, GSM245967, GSM245968, GSM245969, GSM245970, GSM245973
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE9800
Gene Expression Omnibus
Expression signature of cardiac muscle as a potential diagnostic or prognostic tool for dilated cardiomyopathy
7
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