Small molecules which mimic Werdnig-Hoffmann disease
Canned Analysis
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General Information
AccessionDCA00009486
TitleSmall molecules which mimic Werdnig-Hoffmann disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Werdnig-Hoffmann disease gene expression signature in the CNS - Spinal Cord (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cc51e467bea600fb8ad8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:126
Cell TypeCNS - Spinal Cord (MMHCC)
DO IDDOID:13137
Disease NameWerdnig-Hoffmann disease
Organismmouse
UMLS CUIC0043116
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM67523, GSM67524, GSM67525
Perturbed SamplesGSM67526, GSM67529, GSM67530
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3075
Gene Expression Omnibus
Neuromuscular degeneration mutant spinal cord response to neural stem cell transplantation
12
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