Small molecules which reverse Osteolysis
Canned Analysis
FAIR Metrics
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General Information
AccessionDCA00009491
TitleSmall molecules which reverse Osteolysis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Osteolysis gene expression signature in the Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b8fae467bea600fb8150
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:128
Cell TypeLeukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)
Disease NameOsteolysis
Organismhuman
UMLS CUIC0029435
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM11437, GSM11438, GSM11439, GSM11440, GSM11441, GSM11442, GSM11443, GSM11444, GSM11445, GSM11446, GSM11447, GSM11448, GSM11449, GSM11450, GSM11451, GSM11452, GSM11453, GSM11454, GSM11455, GSM11456, GSM11457, GSM11458, GSM11459, GSM11460, GSM11461, GSM11
Perturbed SamplesGSM11473, GSM11474, GSM11475, GSM11476, GSM11477, GSM11478, GSM11479, GSM11480, GSM11481, GSM11482, GSM11483, GSM11484, GSM11485, GSM11486, GSM11487, GSM11488, GSM11489, GSM11490, GSM11491, GSM11492, GSM11493, GSM11494, GSM11495, GSM11496, GSM11497, GSM11
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE755
Gene Expression Omnibus
Multiple myeloma and bone lesions
7
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