Small molecules which reverse prostate cancer
Canned Analysis
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General Information
AccessionDCA00009501
TitleSmall molecules which reverse prostate cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the prostate cancer gene expression signature in the Normal prostate epithelial cells and Primary epithelial cell culture (Gleason 6 score tumor) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c464e467bea600fb86e4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:638
Cell TypeNormal prostate epithelial cells and Primary epithelial cell culture (Gleason 6 score tumor)
DO IDDOID:10283
Disease Nameprostate cancer
Organismhuman
UMLS CUIC0376358
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM88407, GSM88408
Perturbed SamplesGSM88353, GSM88397, GSM88401, GSM88402
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3868
Gene Expression Omnibus
Primary epithelial cell cultures from prostate tumors
21
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