Small molecules which mimic Infantile neuronal ceroid lipofuscinosis
Canned Analysis
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General Information
AccessionDCA00009506
TitleSmall molecules which mimic Infantile neuronal ceroid lipofuscinosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Infantile neuronal ceroid lipofuscinosis gene expression signature in the Brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c53fe467bea600fb8752
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:141
Cell TypeBrain
Disease NameInfantile neuronal ceroid lipofuscinosis
Organismmouse
UMLS CUIC0268281
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM154346, GSM154347, GSM154348, GSM154349, GSM154350, GSM154351, GSM154352, GSM154353, GSM154354
Perturbed SamplesGSM154337, GSM154338, GSM154339, GSM154340, GSM154341, GSM154342, GSM154343, GSM154344, GSM154345
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6678
Gene Expression Omnibus
Palmitoyl protein thioesterase-1 knockout mice hofma-affy-mouse-370000
7
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