Small molecules which mimic scleroderma
Canned Analysis
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General Information
AccessionDCA00009534
TitleSmall molecules which mimic scleroderma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the scleroderma gene expression signature in the Fibroblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c2dce467bea600fb862a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:155
Cell TypeFibroblast
DO IDDOID:419
Disease Namescleroderma
Organismhuman
UMLS CUIC0011644
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM29911, GSM29915, GSM29918
Perturbed SamplesGSM29923, GSM29928, GSM29933
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1724
Gene Expression Omnibus
Idiopathic and scleroderma-associated pulmonary fibrosis derived fibroblasts response to TGFbeta
7
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