Small molecules which reverse muscular dystrophy
Canned Analysis
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General Information
AccessionDCA00009539
TitleSmall molecules which reverse muscular dystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the muscular dystrophy gene expression signature in the Muscle - Striated (Skeletal) - Diaphragm (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c2c0e467bea600fb861c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:158
Cell TypeMuscle - Striated (Skeletal) - Diaphragm (MMHCC)
DO IDDOID:9884
Disease Namemuscular dystrophy
Organismmouse
UMLS CUIC0026850
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM73331, GSM73332, GSM73333, GSM73334
Perturbed SamplesGSM73335, GSM73336, GSM73337, GSM73338
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3252
Gene Expression Omnibus
Alpha2-laminin deficient dy/dy model of muscular dystrophy: diaphragm
12
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