Small molecules which reverse Senescence
Canned Analysis
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General Information
AccessionDCA00009563
TitleSmall molecules which reverse Senescence
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Senescence gene expression signature in the CNS - Brain - Hippocampus (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c0c9e467bea600fb8534
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:161
Cell TypeCNS - Brain - Hippocampus (MMHCC)
Disease NameSenescence
Organismrat
UMLS CUIC0001792
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM13323, GSM13324, GSM13325, GSM13326, GSM13327, GSM13328, GSM13329, GSM13330, GSM13331
Perturbed SamplesGSM13303, GSM13304, GSM13305, GSM13306, GSM13307, GSM13308, GSM13309, GSM13310, GSM13311, GSM13312
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE854
Gene Expression Omnibus
Hippocampal aging and cognitive impairment
7
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