Small molecules which mimic osteoporosis
Canned Analysis
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General Information
AccessionDCA00009564
TitleSmall molecules which mimic osteoporosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the osteoporosis gene expression signature in the Blood monocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c0d8e467bea600fb853a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:163
Cell TypeBlood monocyte
DO IDDOID:11476
Disease Nameosteoporosis
Organismhuman
UMLS CUIC0029456
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM39877, GSM39878, GSM39879, GSM39880, GSM39881, GSM39882, GSM39883, GSM39884, GSM39885, GSM39886
Perturbed SamplesGSM40049, GSM40052, GSM40202, GSM40204, GSM40208, GSM40223, GSM40232, GSM40245, GSM40247
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2208
Gene Expression Omnibus
Bone mineral density and circulating monocytes
7
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