Small molecules which reverse Barrett's esophagus
Canned Analysis
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General Information
AccessionDCA00009569
TitleSmall molecules which reverse Barrett's esophagus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Barrett's esophagus gene expression signature in the Esophagus epithelium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ce99e467bea600fb8bfa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:643
Cell TypeEsophagus epithelium
DO IDDOID:9206
Disease NameBarrett's esophagus
Organismhuman
UMLS CUIC0004763
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM23385, GSM23386, GSM23387, GSM23388, GSM23389, GSM23390, GSM23391, GSM23392
Perturbed SamplesGSM23395, GSM23396, GSM23397, GSM23398, GSM23399, GSM23400, GSM23401, GSM23402
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1420
Gene Expression Omnibus
Barrett's metaplasia progression to adenocarcinoma
19
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