Small molecules which reverse NASH
Canned Analysis
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General Information
AccessionDCA00009603
TitleSmall molecules which reverse NASH
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the NASH gene expression signature in the Liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c977e467bea600fb8972
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:185
Cell TypeLiver
Disease NameNASH
Organismhuman
UMLS CUIC0400966
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM435828, GSM435833, GSM610718, GSM610737, GSM610738
Perturbed SamplesGSM435821, GSM435822, GSM435823, GSM435824, GSM435825, GSM435826, GSM435827, GSM610690, GSM610691, GSM610695, GSM610696, GSM610717
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24807
Gene Expression Omnibus
Increased hemoglobin expression in NASH livers
7
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