Small molecules which mimic ulcerative colitis
Canned Analysis
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General Information
AccessionDCA00009610
TitleSmall molecules which mimic ulcerative colitis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the ulcerative colitis gene expression signature in the PBMC (peripheral blood mononuclear cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c119e467bea600fb855a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:762
Cell TypePBMC (peripheral blood mononuclear cells)
DO IDDOID:8577
Disease Nameulcerative colitis
Organismhuman
UMLS CUIC0375359
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM76115, GSM76116, GSM76117, GSM76118, GSM76119, GSM76120, GSM76121, GSM76122, GSM76123, GSM76124, GSM76125, GSM76126, GSM76127, GSM76128, GSM76129, GSM76130, GSM76131, GSM76132, GSM76133, GSM76134, GSM76135, GSM76136, GSM76137, GSM76138, GSM76139, GSM76
Perturbed SamplesGSM76030, GSM76031, GSM76032, GSM76033, GSM76034, GSM76035, GSM76036, GSM76037, GSM76038, GSM76039, GSM76040, GSM76041, GSM76042, GSM76043, GSM76044, GSM76045, GSM76046, GSM76047, GSM76048, GSM76049, GSM76050, GSM76051, GSM76052, GSM76053, GSM76054, GSM76
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3365
Gene Expression Omnibus
Ulcerative colitis and Crohn's disease comparison: peripheral blood mononuclear cells
19
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